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Full-Text Articles in Entire DC Network
The Effect Of Education On Green Growth And Carbon Emissions, 1990–2022, Soojeong Ahn
The Effect Of Education On Green Growth And Carbon Emissions, 1990–2022, Soojeong Ahn
Electronic Theses & Dissertations (2024 - present)
The question of whether education promotes economic growth has long been a central topic in development research, and education has been linked to economic outcomes through macro-level pathways such as human capital accumulation, productivity growth, and technological diffusion. More recently, this discussion has expanded beyond economic growth to consider whether education contributes to environmentally sustainable development, particularly green growth. Green growth emphasizes the possibility of sustaining economic expansion while reducing environmental pressure (OECD, 2011; UNEP, 2011), and this study therefore examines how education is related to green growth and carbon emissions at the macro level.
At the macro level, existing …
Developments And Applications Of Transport Of Intensity Equation Imaging And Optical Diffraction Tomography In Bioimaging, Shane D. Carney
Developments And Applications Of Transport Of Intensity Equation Imaging And Optical Diffraction Tomography In Bioimaging, Shane D. Carney
Electronic Theses & Dissertations (2024 - present)
Non-invasive imaging schemes are highly sought after methodologies in biology and metrology, where maintaining the physical state of a sample is important. Quantitative phase imaging (QPI) techniques non-invasively reconstruct the relative phase delay imparted onto an optical field due to transmission through a sample. Phase delay is proportional to the thickness and refractive index of the sample, but is lost in the intensity measurement process. Digital holographic microscopy (DHM) and transport of intensity equation (TIE) phase imaging are two high-resolution QPI techniques. DHM is a well-researched, accurate, and widely implemented technique, but can be difficult to implement in labs without …
Politics Of A Silent Pandemic: Antimicrobial Resistance And State Capacity In India And Nigeria, Mia Kelly
Politics Of A Silent Pandemic: Antimicrobial Resistance And State Capacity In India And Nigeria, Mia Kelly
CMC Senior Theses
Antimicrobial Resistance (AMR) has emerged as one of the most pressing yet widely underestimated health threats of the 21st century; this thesis explores the potentially devastating global impact of this “silent pandemic”, exposing how deeply health outcomes depend on political choices, regulatory capacity, and economic constraints. Although the danger of spreading drug-resistant pathogens is now widely acknowledged in both the scientific and political communities, states differ in their abilities to contain the issue, with low- and middle-income countries facing the greatest obstacles to national action plan implementation. This thesis investigates these disparities through a comparison of India and Nigeria, two …
Systematic Literature Review: Elevating Black Voices Through Universal Social-Emotional Learning Interventions, Natasha J. Hogg
Systematic Literature Review: Elevating Black Voices Through Universal Social-Emotional Learning Interventions, Natasha J. Hogg
Electronic Theses & Dissertations (2024 - present)
This systematic literature review examined the outcomes of culturally responsive universal Social-Emotional Learning (SEL) interventions for Black students in K-12 school settings addressing mental health, racial trauma, and racial disparities. Following the PRISMA protocol, a comprehensive search was conducted across PsycINFO, EBSCO, and five academic journals by April 2025. Results yielded 11 peer-reviewed articles with 2,246 Black participants published between 1994 and 2024. Exclusion criteria included sole focus of Tier 2 or 3 interventions, lacking Black student populations, or lacking outcomes aggregated by race. Seven SEL interventions were identified with risk of bias assessed by a secondary reviewer. Thematic analysis …
Bonny And Read: Navigating The Waters Between Truth And Tale, Fiona J. Faccilonga
Bonny And Read: Navigating The Waters Between Truth And Tale, Fiona J. Faccilonga
Electronic Theses & Dissertations (2024 - present)
This thesis examines piracy, cross-dressing, gender fluidity, and ambiguous identity in the lives of Anne Bonny and Mary Read as represented in A General History of the Pyrates by Captain Charles Johnson. This thesis argues that Johnson’s narrative reshapes their piracy through feminine frameworks to align them with patriarchal expectations of womanhood and fixed identity. Specifically, he uses the breast and the belly as sites of gendered truth, attempting to reduce their masculine presentation as mere performance rather than intrinsic identity.
However, despite Johnson’s attempt at narrative authority, Bonny and Read ultimately resist such containment. Through close readings of both …
Bioinformatic Identification And Analysis Of Shared Splicing Errors In Myotonic Dystrophy Type (Dm1) And Fuchs' Endothelial Corneal Dystrophy (Fecd), Carter I. Wilkins
Bioinformatic Identification And Analysis Of Shared Splicing Errors In Myotonic Dystrophy Type (Dm1) And Fuchs' Endothelial Corneal Dystrophy (Fecd), Carter I. Wilkins
Electronic Theses & Dissertations (2024 - present)
Myotonic dystrophy type 1 (DM1) is an autosomal dominant form of muscular dystrophy, and it is the most common form of adult-onset muscular dystrophy. The disease is the result of CTG trinucleotide repeats (TNR) in the 3’UTR of the dystrophia myotonica protein kinase (DMPK) gene. This produces toxic RNA hairpin structures by CUG repeat expansions that sequester proteins–most relevantly muscleblind-like 1 (MBNL)–that regulate alternative RNA splicing. The missplicing of a wide variety of genes results in the symptoms such as myotonia (rigidity of the muscles), atrophy, and cardiac failure.
Fuchs’ Endothelial Corneal Dystrophy (FECD) is characterized by progressive loss and …
Barriers And Corridors: Timber Rattlesnake Habitat Connectivity In New York, Lauren Rose
Barriers And Corridors: Timber Rattlesnake Habitat Connectivity In New York, Lauren Rose
Electronic Theses & Dissertations (2024 - present)
Habitat fragmentation poses a significant threat to species that rely on landscape connectivity for movement in search of food, water, and mates. The timber rattlesnake (Crotalus horridus), listed as a threatened species in New York State, travels an average of 1.5 miles—and up to five miles—from permanent denning sites to reach habitat suitable for gestation, foraging, basking, and overwintering. Ongoing development in the lower Hudson Valley has increasingly fragmented these critical habitats, restricting movement between den populations. This thesis evaluates landscape barriers that contribute to population isolation and identifies opportunities to restore connectivity among timber rattlesnake metapopulations.
Using …
Multifunctional And Adaptive: Tracking How Fibroblasts Respond To Tissue Injury And Facilitate Tissue Remodeling, Joey R. Tavarez
Multifunctional And Adaptive: Tracking How Fibroblasts Respond To Tissue Injury And Facilitate Tissue Remodeling, Joey R. Tavarez
Electronic Theses & Dissertations (2024 - present)
Fibrosis is characterized by an accumulation of proteins in the extracellular matrix (ECM) that results in altered tissue architecture and reduced organ function. In the salivary glands, fibrosis leads to loss of saliva, dysbiosis of the oral microbiome, an increase in oral infections, difficulty in digestion of food and an overall reduction in the quality of life. Understanding the progression of fibrosis and how it affects human health is a crucial step for designing effective therapeutics. Understanding fibroblast function is integral to advancing the field due to the many roles they play in maintaining the ECM. To perform preliminary analysis, …
Constructing The Political “Other”: Affective Polarization And Cross-Ideological Portrayals On Instagram, Amanda M. Novellin
Constructing The Political “Other”: Affective Polarization And Cross-Ideological Portrayals On Instagram, Amanda M. Novellin
Electronic Theses & Dissertations (2024 - present)
Instagram has frequently been characterized by users as a platform that permits the circulation of hostile and adversarial political content due to comparatively limited moderation practices. In January 2025, Meta CEO Mark Zuckerberg announced changes to content moderation policies on Facebook and Instagram, including the removal of third-party fact-checking mechanisms. These platform-level changes further reshaped the political information environment in which online discourse occurs. However, even prior to these policy changes, Instagram had established itself as a prominent space for highly polarized political expression across the ideological spectrum.
This thesis examines how political polarization in the United States is reflected …
Specification Of Validated Groundwater Flow And Transport Models For Historical Perfluorinated Compound Dose Reconstruction, Cindy A. Arthur
Specification Of Validated Groundwater Flow And Transport Models For Historical Perfluorinated Compound Dose Reconstruction, Cindy A. Arthur
Electronic Theses & Dissertations (2024 - present)
Per- and polyfluoroalkyl substance (PFAS) contamination in Hoosick Falls, New York, resulted from historical industrial activities, with groundwater transport identified as the primary pathway impacting the municipal wellfield within the Village of Hoosick Falls, whereas atmospheric deposition remains a potential source of private well contamination. This study employed two complementary methodologies to evaluate historical municipal and private well contamination: (i) groundwater flow and transport modeling of PFOA, PFOS, PFHxS, and PFNA within the village, and (ii) Geographic Information Systems (GIS)–based inverse distance weighting (IDW) interpolation of PFOA concentrations in private wells across the broader Town of Hoosick.
Groundwater modeling results …
Development Of Photolabile Coumarin Linker For Rna Synthesis And Crisprcas9 Applications, Ian Mcclain
Development Of Photolabile Coumarin Linker For Rna Synthesis And Crisprcas9 Applications, Ian Mcclain
Electronic Theses & Dissertations (2024 - present)
The scope of RNA-based therapeutics continues to expand as more siRNA, mRNA, and CRISPR-based treatments are approved for various medical applications. Purification of synthetic RNA drugs is inherently challenging and requires considerable time and resources. New cost-effective and efficient purification strategies will expedite drug development process and will lower the drug costs. In this thesis I describe two generations of photolabile linkers for the non-chromatographic purification of therapeutic RNAs. In addition, the photolabile linker was utilized for regulation CRISPR-Cas9 gene editing. In the first part of the thesis, I describe the first generation of the photolabile coumarin-based linker for non-chromatographic …
Academic Drift In Indonesian Islamic Higher Education: An Empirical Study Of The State Islamic University Of Mataram, Ade Alimah
Electronic Theses & Dissertations (2024 - present)
Many higher education institutions imitate one another to achieve upward movement, a phenomenon known as academic drift. While this trend is widely acknowledged, the existing academic literature primarily focuses on developed nations. This research aims to investigate how academic drift occurs in Indonesian Islamic higher education, particularly through institutional transformations that involve institutes transitioning to universities.
This qualitative study examines academic drift at the State Islamic University of Mataram, Indonesia. To gather extensive data, in-depth interviews were conducted with participants from this university, representatives from two leading public Islamic universities, and senior officials from the Ministry of Religious Affairs.
Our …
Criminalizing Motherhood: Abortion, Obstetric Emergencies, And State Power In Post-1998 El Salvador, Valery M. Reyes
Criminalizing Motherhood: Abortion, Obstetric Emergencies, And State Power In Post-1998 El Salvador, Valery M. Reyes
CMC Senior Theses
This thesis examines how a series of regressive legal reforms in El Salvador–the 1997 Penal Code’s expansion of abortion-related punishments and the 1999 constitutional amendment defining life as beginning at conception–eliminated all exceptions to abortion and transformed a woman’s reproductive body into a site of surveillance. Rather than expanding rights, these reforms rolled back on existing protections by not recognizing obstetric emergencies, miscarriages, or cases of rape as legitimate grounds for abortion. Prosecutors and judges could treat such medical emergencies as convictions for “fetal homicide,” carrying sentences of 30-50 years in prison.
Court documents, reports from non-government organizations …
Loan-Heavy Aid: Consequences On Academic And Early-Career Outcomes, April Zhang
Loan-Heavy Aid: Consequences On Academic And Early-Career Outcomes, April Zhang
CMC Senior Theses
This study examines how the composition of financial aid, specifically the balance between loans and grants, shapes students’ academic performance, major selection, and early career outcomes. Using administrative data from the University of California system (2007-2019) and post-graduation records from UC Irvine, I analyze how loan reliance influences both educational trajectories and labor-market results. The key measure, loanshare, captures the fraction of total aid financed through loans rather than grants. This allows for comparisons among students with similar financial need, expected family contribution, and total aid levels. Results show that students with more loan-heavy aid packages earn significantly lower …
The Communicative Constitution Of Resilience In Graduate-Student Parenthood: Ventriloqual Analysis, Intersectionality, And Sociomaterial Assemblages, Lin Lin
Electronic Theses & Dissertations (2024 - present)
Graduate education is often organized around norms of uninterrupted productivity, flexibility, and professional availability, making graduate study especially challenging for students who are simultaneously raising children. Although prior research has documented the structural barriers faced by graduate student parents (GSPs), less attention has been paid to how resilience is communicatively enacted within the intersection of academic work and family life. This dissertation examines how GSPs communicatively constitute resilience while navigating work-life disruptions. Drawing on Communication Theory of Resilience (CTR) and the communicative constitution of organizations (CCO) perspective, particularly ventriloqual analysis, this study explores how resilience emerges through interactions among human …
Development And Applications Of Fluorescence Microscopy Protocol To Investigate Borrelia Burgdorferi Immune Interactions In The Skin, Rebecca V. Landry
Development And Applications Of Fluorescence Microscopy Protocol To Investigate Borrelia Burgdorferi Immune Interactions In The Skin, Rebecca V. Landry
Electronic Theses & Dissertations (2024 - present)
The skin is an immunological organ that acts as the hosts’ first line of defense against infectious agents. Infectious disease vectors like ticks breach this barrier by feeding on hosts, transmitting pathogens like Borrelia burgdorferi in the process. Uncleared infection with B. burgdorferi causes Lyme disease, the most prevalent vector-borne disease in the United States. Previous research has explained many elements of Lyme disease pathogenesis and immunity including the dissemination of the spirochete, innate immune cells performing phagocytosis, the production of antibodies by the humoral response, and the impact of prophylactic treatment with monoclonal antibodies. A remaining gap in the …
A Moderated Mediation Analysis Of Mental Health Literacy, Personal Stigma, And Gender On Help-Seeking Intentions In College Students, Anna M. Gentile
A Moderated Mediation Analysis Of Mental Health Literacy, Personal Stigma, And Gender On Help-Seeking Intentions In College Students, Anna M. Gentile
Electronic Theses & Dissertations (2024 - present)
Although many college students experience mental health challenges, help-seeking rates remain disproportionately low relative to reported need (Abelson et al., 2022). Identifying factors that facilitate help-seeking is critical for improving access to mental health support in this population. Prior research has identified mental health literacy as a significant predictor of help-seeking behavior and intentions among college students (Gorczynski et al., 2017; Smith & Shochet, 2011), whereas personal stigma, which is defined as a person’s negative attitude towards people with mental health concerns (Griffiths et al., 2006), has been consistently associated with reduced help-seeking (Abelson et al., 2022). Grounded in the …
Combating Antibiotic Resistance With Plasmid-Dependent Phages, Rhiannon T. Mariano
Combating Antibiotic Resistance With Plasmid-Dependent Phages, Rhiannon T. Mariano
Electronic Theses & Dissertations (2024 - present)
The alarming rise of carbapenem-resistant bacteria poses an urgent global health threat, driven in large part by the horizontal spread of carbapenemase-encoding plasmids (Ma et al., 2023). These plasmids are often highly mobile and transmissible, enabling rapid dissemination of resistance genes across diverse bacterial populations. Their mobility is largely mediated by conjugation, a process dependent on the formation of pili, which serve as physical bridges for plasmid transfer between cells (Murray et al. 2022; San Millan and MacLean 2017; Virolle et al. 2020). Beyond their role in gene exchange, these pili also act as entry points for a unique class …
Psychometric Assessment Of The Facilitative Systemic Intervention Skills Rating System– Spanish Version, Sarah J. Crosky
Psychometric Assessment Of The Facilitative Systemic Intervention Skills Rating System– Spanish Version, Sarah J. Crosky
Electronic Theses & Dissertations (2024 - present)
Despite the growing understanding of therapist factors in client outcomes, there remains limited understanding of the skills that distinguish effective family therapists. The aim of the present study was to assess the interrater reliabilities and factorial structure of a Spanish version of the Facilitative Systemic Intervention Skills (FSIS; Jones et al., 2023a), an observational rating system for evaluating the skillfulness of family therapists in delivering systemic interventions. The FSIS includes eight empirically and theoretically informed systemic therapy skills (Inclusiveness, Empathy for Relational Difficulties, Responsiveness to Safety Concerns, Collaborative Stance, Conceptualizing Family Problems Systemically, Responsiveness to Disparate Goals, Focus on Family …
Victimized And Criminalized: The Intertwined Narratives Of Trauma And Offending, Caitlin Maria Udas
Victimized And Criminalized: The Intertwined Narratives Of Trauma And Offending, Caitlin Maria Udas
Electronic Theses & Dissertations (2024 - present)
How do pathways between childhood victimization, drug use, and offending behavior vary for recordholders of different races and genders? Prior literature and theory indicates that there are distinct processes that can link childhood victimization to drug use and other offending behavior. These processes are rooted at least partially in experiences of racism/discrimination, placement relative to sociocultural power structures, and norms established over one’s childhood through peer and familial influences. However, less is known about how these differ by race, gender, and the intersection thereof. This dissertation examines the intersectional differences in narrative pathways that link childhood victimization, drug use, and …
The Economics Of The U.S. Student Loan Market And The Case For The Education Development Financial Institution, Ian Akers
CMC Senior Theses
The United States student loan market is shaped by a variety of market failures–credit constraints, positive externalities, behavioral frictions including myopia, debt aversion, and misperception–that together justify government intervention in the market. Yet the design of federal intervention is just as important as its existence. This thesis details the economic theory underpinning the market for student loans, evaluates three historical federal student loan programs (the Perkins Loan Program, the Federal Family Education Loan Program, and the Federal Direct Loan Program) through the lens of that theory. The thesis then proposes a novel institutional model as a targeted response to the …
Revenge Of The Interceptors? The Dod, Congress, And The Return Of Space-Based Missile Defense During Trump 45, Chad Mcelroy
Revenge Of The Interceptors? The Dod, Congress, And The Return Of Space-Based Missile Defense During Trump 45, Chad Mcelroy
CMC Senior Theses
The initiation of the Golden Dome for America program has brought space-based missile defense (SBMD) to the forefront of American national security policy and rekindled debates that had laid dormant since the administration of President Ronald Reagan. How, forty-two years after President Reagan first proposed the Strategic Defense Initiative, did SBMD return as a national priority? In lieu of public information about the ongoing Golden Dome initiative, this thesis explores the first Trump administration, otherwise known as Trump 45, in order to analyze the development of SBMD proposals by its proponents in Congress and the Department of Defense. I used …
Goods, Practices, Excellence, And The Law: Steps To An Internal Theory Of Value, Rowan Gray
Goods, Practices, Excellence, And The Law: Steps To An Internal Theory Of Value, Rowan Gray
CMC Senior Theses
Practices are the coherent and complex social activities we spend much of our lives engaging in. This category encompasses everything from figure skating to wine-tasting to friend relationships. We gain immense value from participating in practices, and philosophers have articulated a number of accounts for where the value emerges from and how we can best experience it. Many of these theories are ‘externalist’, because they posit that value is incidental to practices and emerges from outside of them.
In contrast, this thesis will argue that the value in practices is internal to each practice. The value comes from each practice’s …
Psr Impacts Chromatin Condensation During Spermatogenesis In Nasonia Vitripennis, Jacqueline R. Solomon
Psr Impacts Chromatin Condensation During Spermatogenesis In Nasonia Vitripennis, Jacqueline R. Solomon
CMC Senior Theses
Paternal Sex Ratio (PSR) is a supernumerary, selfish B chromosome found in the jewel wasp (Nasonia vitripennis). PSR is transmitted strictly paternally to progeny, and when present, it causes paternal genome elimination (PGE) just after fertilization. Due to the haplo-diploid reproduction of N. vitripennis, this PGE event results in all-male broods of progeny, ~90% of which carry and transmit PSR. Thus, PGE is beneficial for PSR’s transmission. A previous study showed that PSR induces PGE by expressing a gene called haploidizer during spermatogenesis. Although how haploidizer functions in PGE is unknown, this finding suggests two basic models: that (i) the …
Exploration Of The Use Of Radiocarbon Time-Series Records As Indicators Of Upwelling Areas, Rena Reshmi Mukherjee
Exploration Of The Use Of Radiocarbon Time-Series Records As Indicators Of Upwelling Areas, Rena Reshmi Mukherjee
CMC Senior Theses
The Earth’s oceans buffer climate change, regulate weather patterns, sustain global food security, and support biomedical research. Ocean currents redistribute heat and nutrients while promoting genetic diversity, which can serve as a source of novel compounds for biomedical research. Understanding ocean circulation is essential for maintaining these ecosystem services as the climate continues to change. Upwelling, a form of vertical water movement that transports nutrient-rich deep water to the surface, plays a key role in marine productivity and carbon cycling. However, global upwelling patterns remain incompletely mapped. Radiocarbon (14C), a radioactive isotope of carbon, provides a useful tracer of ocean …
Mapping Ubiquitin-Cavitand Binding Interactions Using Ccpnmr Analysis, Mia J. Rhee
Mapping Ubiquitin-Cavitand Binding Interactions Using Ccpnmr Analysis, Mia J. Rhee
CMC Senior Theses
Ubiquitin is a highly conserved 76-residue protein central to proteasomal degradation, DNA repair, and immune regulation. Its dysfunction underlies neurodegenerative diseases and cancer, so it is important to understand how synthetic molecules recognize ubiquitin’s surface at residue level as it has implications for biosensor design and therapeutic targeting. This study performs a quantitative analysis of ubiquitin-cavitand binding interacting using four 1H-15N HSQC NMR titration spectra collected across increasing tetracarboxylate cavitand concentrations (apo, 1:15, 1:2, and 1:3 cavitand:ubiquitin). Using CCPNMR AnalysisAssign, all 73 non-proline backbone amide resonances were assigned against published BMRB reference shifts.The chemical shift perturbations (CSPs) were calculated at …
Modulating Oran Nitrate-Reducing Bacteria To Enhance Nitric Oxide Bioavailability As A Therapeutic Target For Atherosclerosis, Donovan C. Davidson
Modulating Oran Nitrate-Reducing Bacteria To Enhance Nitric Oxide Bioavailability As A Therapeutic Target For Atherosclerosis, Donovan C. Davidson
CMC Senior Theses
Atherosclerosis remains the primary driver of global cardiovascular disease, yet clinical interventions are largely restricted to high-cost, invasive procedures only after it has reached a critical stage. Recent research has identified a connection between the oral microbiome and vascular health via the enterosalivary nitrate-nitrite-nitic oxide (NO) pathway. Oral nitrate-reducing bacteria (ONRB) drive the synthesization of NO by reducing dietary nitrate into nitrite, which is then converted into bioavailable NO. NO is a potent vasodilator that maintains endothelial health by suppressing inflammation through inhibiting the expression of adhesion molecules VCAM-1 and ICAM-1. However, this pathway is easily compromised by dysbiotic oral …
Not Biological, But Built: Structural And Metabolic Pathways Driving Black Maternal Health Disparities In The United States, Alexandra I. Umegboh
Not Biological, But Built: Structural And Metabolic Pathways Driving Black Maternal Health Disparities In The United States, Alexandra I. Umegboh
CMC Senior Theses
Black infants in the United States are more than twice as likely to die before their first birthday than white infants, a disparity often attributed to genetics, behavior, or individual health choices. However, this idea is challenged by a key contradiction: African immigrant women consistently experience better birth outcomes than U.S.-born Black women despite being similarly racialized. This thesis investigates the origins of this reproductive advantage and the factors contributing to its decline over time. By drawing on epidemiological data, metabolic health research, and literature on African diasporic healing traditions, it argues that the “healthy immigrant effect” is not biological, …
Too Much Of A Good Thing? Generic Entry, Drug Prices, And The Innovation Tradeoff, Kiara Jacob
Too Much Of A Good Thing? Generic Entry, Drug Prices, And The Innovation Tradeoff, Kiara Jacob
CMC Senior Theses
This paper examines how the number of generic competitors affects generic drug prices and whether generic markets exhibit a competition threshold beyond which additional entry produces little further price reduction. Using monthly NADAC price data and FDA Orange Book manufacturer records, I construct a molecule-month panel of 17 molecules across four therapeutic classes from 2013 to 2023, restricted to generic price observations. Fixed-effects regressions show that generic competition is associated with substantial price declines: each additional generic manufacturer is associated with a 7.2 log-point reduction in average acquisition price. The main threshold specification shows that prices are approximately 49 percent …
Intermittent High-Fat, High-Sugar Access During Adolescence Drives Binge-Restriction Feeding And Reduced Weight Gain In A Food Unpredictability Model, Calvin G. Miller
Intermittent High-Fat, High-Sugar Access During Adolescence Drives Binge-Restriction Feeding And Reduced Weight Gain In A Food Unpredictability Model, Calvin G. Miller
CMC Senior Theses
Food insecurity affects nearly 48 million Americans and 318 million people worldwide, with very low food security disrupting normal eating habits through “feast-or-famine” episodes characterized by cycles of food overconsumption followed by restriction. This dietary pattern alters dopamine signaling within the mesocorticolimbic system — brain circuitry intimately linked to reward processing. This system includes the ventral tegmental area (VTA) and prefrontal cortex (PFC). Overstimulation can be promoted through sporadic high-fat, high-sugar diet (HFHSD) exposure, promoting dopamine neuron architecture alterations and binge-eating behavior. Adolescence represents a vulnerable window, as mesocorticolimbic dopamine projections undergo maturation during this period. Though evidence links food …