Digital Commons Network^™

The Cost Of Poverty: The Perpetuating Cycle Of Concentrated Poverty In New Jersey Cities • A Comprehensive Budgetary Analysis Of Four Urban New Jersey Municipalities, John S. Watson Institute For Public Policy Of Thomas Edison State University, New Jersey Urban Mayors Association, The Anti-Poverty Network Of New Jersey, Fund For New Jersey

Urban Mayors Policy Center

This report examines the problem of concentrated poverty in the State of New Jersey. Both the individual and the long-term economic consequences of concentrated poverty are well- documented in social science research. The report adds to that knowledge by examining the practical, budgetary consequences faced by urban centers that are characterized by high poverty levels. The report focuses on four cities, which are represented in the New Jersey Urban Mayors Association (NJUMA) — Bridgeton, Passaic, Perth Amboy, and Trenton. While these regions vary considerably, they all share one important fact: their poverty rates are double or triple the New Jersey …

College Of Pharmacy Annual Report For Fy2016, Uri College Of Pharmacy

College of Pharmacy Reports

Annual report for the College of Pharmacy of the University of Rhode Island for the year 2015-2016.

Includes information and statistics for the academic programs, research work and developments by faculty and students, community engagement and donations.

Bisphenol A Sulfonation Is Impaired In Metabolic And Liver Disease, Emine B. Yalcin, Supriya R. Kulkarni, Angela L. Slitt, Roberta King

Biomedical and Pharmaceutical Sciences Faculty Publications

Background: Bisphenol A (BPA) is a widely used industrial chemical and suspected endocrine disruptor to which humans are ubiquitously exposed. The liver metabolizes and facilitates BPA excretion through glucuronidation and sulfonation. The sulfotransferase enzymes contributing to BPA sulfonation (detected in human and rodents) is poorly understood.

Objectives: To determine the impact of metabolic and liver disease on BPA sulfonation in human and mouse livers.

Methods: The capacity for BPA sulfonation was determined in human liver samples that were categorized into different stages of metabolic and liver disease (including obesity, diabetes, steatosis, and cirrhosis) and in livers from ob/ob mice.

Results: …

Effects Of A Standardized Phenolic-Enriched Maple Syrup Extract On Β-Amyloid Aggregation, Neuroinflammation In Microglial And Neuronal Cells, And Β-Amyloid Induced Neurotoxicity In Caenorhabditis Elegans, Hang Ma, Nicholas A. Dasilva, Weixi Liu, Pragati P. Nahar, Zhengxi Wei, Yongqiang Liu, Priscilla T. Pham, Rebecca Crews, Dhiraj A. Vattem, Angela L. Slitt, Zahir A. Shaikh, Navindra P. Seeram

Biomedical and Pharmaceutical Sciences Faculty Publications

Published data supports the neuroprotective effects of several phenolic-containing natural products, including certain fruit, berries, spices, nuts, green tea, and olive oil. However, limited data are available for phenolic-containing plant-derived natural sweeteners including maple syrup. Herein, we investigated the neuroprotective effects of a chemically standardized phenolic-enriched maple syrup extract (MSX) using a combination of biophysical, in vitro, and in vivo studies. Based on biophysical data (Thioflavin T assay, transmission electron microscopy, circular dichroism, dynamic light scattering, and zeta potential), MSX reduced amyloid β₁₋₄₂ peptide (Aβ₁₋₄₂) fibrillation in a concentration-dependent manner (50–500 μg/mL) with similar effects as the …

Correlates Of Quality Of Life In Overweight Or Obese Breast Cancer Survivors At Enrollment Into A Weight Loss Trial, Bilge Pakiz, Patricia A. Ganz, Rebecca L. Sedjo, Shirley W. Flatt, Wendy Demark-Wahnefried, Jingxia Liu, Kathleen Y. Wolin, Cheryl L. Rock

Biostatistics Faculty Publications

No abstract provided.

Estimates Of Mental Health Problems In A Vulnerable Population Within A Primary Care Setting, Darrell L. Hudson, Kimberly A. Kaphingst, Merriah A. Croston, Melvin S. Blanchard, Melody S. Goodman

Health Disparities Faculty Publications

No abstract provided.

Cardiac Autonomic Control In Patients With Metabolic Syndrome, Jonathan Mitchell

Electronic Theses and Dissertations

Metabolic syndrome (MetS) encompasses metabolic abnormalities that substantially increase risk for chronic illnesses. MetS and stress are closely related; the pathophysiology of MetS involves dysregulated stress response in both the physiological and psychological domains. In an effort to further clarify the relationship between metabolic abnormalities and autonomic dysregulation, we used ambulatory impedance cardiography to examine indicators of cardiac autonomic control (CAC) in a sample of 50 adult primary care patients with and without MetS. Indices of sympathetic and parasympathetic influences on cardiovascular functioning were assessed in the context of psychological stressors and compared across experimental groups and examined in relation …

Attitudes And Experiences With Older Adults: A Case For Service Learning For Undergraduates, Hardeep Obhi, Erin Woodhead

Faculty Publications

The current study examined whether relationship quality with older adults currently and in childhood, as well as experience with older adults, was associated with biases toward older adults and interest in working with older adults as a possible career area. The authors sampled undergraduate students (N = 753, M = 18.97 years, SD = 2.11 years) from a Northern California university. In hierarchical regression analyses, higher perceived quality of relationships with older adult family members, higher perceived social support, and lower perceived conflict from relationships with older adults was significantly associated with positive attitudes toward older adults. Interest in …

Effect Of Diallyl Trisulfide On Hedgehog Signaling In Pancreatic Cancer Cells, Michael Puccinelli

Open Access Theses

With an increasing global cancer burden, new methods of cancer prevention are desired to improve overall survival. In particular, pancreatic cancer (PC) is in desperate need of new strategies to improve the dismal 8% overall 5-year survival rate. Studies have shown aberrant activation of the Hedgehog pathway to be associated with very poor prognosis in multiple cancer types, including pancreatic. Prevention strategies utilizing dietary agents have been shown to regulate multiple cancer hallmark pathways, but little is known regarding their effect on Hedgehog. Here we observed diallyl trisulfide (DATS), an anti-cancer agent found in garlic, reduced colony formation and inhibited …

University Of South Alabama College Of Medicine Annual Report For 2016-2017, College Of Medicine

COM Annual Reports

This Annual Report of the College of Medicine catalogues accomplishments of our faculty, students, residents, fellows and staff in teaching, research, scholarly and community service during the 2016-2017 academic year.

Wolbachia And Sex, Ian J. Aper, Katie Weglarz, Carol Von Dohlen

Biology Posters

Insects with complex life cycles provide an ideal system for investigating the relationship between sex-skewing bacterial symbionts and the secondary loss of sexual reproduction. This research utilized the insect family Adelgidae, a group notorious for having peculiar and complex life cycles. In this family, some species have lost their sexual generation entirely, trapping them in asexual reproduction. Additionally, these insects are known to harbor multiple symbionts, both obligate and facultative. The array of facultative symbionts that have been detected includes the infamous sex-skewing symbiont Wolbachia. This symbiont is known to induce male killing, cytoplasmic incompatibility, and parthenogenesis in insects. Additionally, …

The Identification And Characterization Of Bacterial Endosymbionts In The Planthopper Family, Issidae (Sternorrhyncha:Fulgoroidea), Lina Ghabayen

Biology Posters

Many insects live on nutrient-poor diets; to compensate, they have evolved obligate associations with microorganisms that are transmitted directly between generations. The bacterial associates of some Hemiptera insects have been identified and understood, but several remain unknown. Our objective is to identify the diversity of bacterial endosymbionts in Issidae using modern microscopy and molecular methods, and compare their identities to known symbionts from related insects. To do so, we will extract DNA from insect samples, amplify bacterial symbiont 16S genes, sub-clone PCR products, sequence the products, and determine their phylogenetic relationships to other insect symbionts and free-living bacteria. Our study …

Make Everyday Count And Always Believe In Yourself, Marissa Kee

Biology Posters

No abstract provided.

My Stem Experience, Catari Curley

Biology Posters

No abstract provided.

Annual Report, Fiscal Year 2015-2016, Tennessee. Department Of Human Services

Annual Reports

This annual report highlights the accomplishments of the Department of Human Services for the fiscal year.

Breaking Down Barriers: The Intersection Of Medicine And Faith, Kaitlyn Lindgren, Ashley Kethcart

Honors Program: Student Scholarship & Creative Works

While medicine and faith are often presented as contradictory concepts, the two play complementary roles in people's health. Christian prayer and Buddhist meditation practices have an impact on health, as well as alternative forms of medicine. These influences can work in tandem to increase the mental and physical health of all people and also demonstrate that science and faith need not always be in opposition.

Prevalence And Related Factors Of Psoriasis And Seborrheic Dermatitis: A Community Based Study, Yalçin Baş, Havva Yildiz Seçki̇n, Göknur Kalkan, Zennure Takci, Riza Çitil, Yalçin Önder, Şafak Şahi̇n, Ayşe Kevser Demi̇r

Turkish Journal of Medical Sciences

No abstract provided.

Serological Prevalence Of Human Parvovirus B19 In Diseases Or Disordersrelated To Different Human Body Systems, Osman Aktaş, Hakan Aydin, Hakan Uslu

Turkish Journal of Medical Sciences

Background/aim: Human parvovirus B19 is a pathogen that affects different parts of the body. We planned this study because of the lack of data on B19 seroprevalence based on different body-system diseases. Materials and methods: The prevalence of parvovirus B19 antibodies was investigated retrospectively in 1239 patients by review of medical records from 2009-2012, according to their diseases classified under general titles in compliance with the International Classification of Diseases (ICD-10). Parvovirus B19-specific antibodies were detected by quantitative enzyme immunoassays. Results: The positivity rate was 27.8% for only IgG, 8.5% for only IgM, and 2.6% for both IgG and IgM. …

The Effect Of Enteral Immunonutrition In Upper Gastrointestinalsurgery For Cancer: A Prospective Study, Seli̇m Yi̇ği̇t Yildiz, Murat Burç Yazicioğlu, Çağri Ti̇ryaki̇, Ali̇ Çi̇ftçi̇, Zehra Boyacioğlu, Mehmet Özyildiz, Murat Coşkun, Özkan Subaşi

Turkish Journal of Medical Sciences

Background/aim: Enteral feeding and immunonutrition (ImN) have been shown to be associated with a number of favorable effects in patients undergoing cancer surgery. In this prospective study, we aimed to assess the perioperative use of enteral immunonutrition in patients undergoing radical gastrointestinal surgery for malignancy. Materials and methods: Forty-one patients with malignancy were included in this study and were randomized into one of the two following nutritional strategies: enteral only (EN) or enteral with enteral immunonutrition (ENIN). These regimens were followed for 7 days perioperatively by all patients. Nutritional parameters and postoperative morbidity, mortality, and length of hospital stay (LHS) …

Glycemic Index Values Of Monofloral Turkish Honeys And The Effect Oftheir Consumption On Glucose Metabolism*, Ali̇ Ti̇muçi̇n Atayoğlu, Meltem Soylu, Si̇bel Si̇li̇ci̇, Neri̇man İnanç

Turkish Journal of Medical Sciences

Background/aim: Clinical trials have shown that low glycemic index (GI) nutrition reduces mean blood glucose concentrations and insulin secretions. The aim of the present study was to determine the GI values of various monofloral (citrus, milk-vetch, chestnut, thyme, lime, pine) honeys of Turkey, and the effect of their consumption on glucose metabolism. Materials and methods: Processing data from 20 healthy volunteers, GI values were determined from the glycemia values by using the incremental area method. Serum insulin and C-peptide levels were also measured before and 120 min after the test. Results: The GI values of citrus, thyme, lime, chestnut, pine, …

Evaluation Of Maternal Serum Folate, Vitamin B12, And Homocysteine Levels Andfactor V Leiden, Factor Ii G.20210g>A, And Mthfr Variations In Prenatallydiagnosed Neural Tube Defects, Hati̇p Aydin, Resul Arisoy, Ali̇ Karaman, Emre Erdoğdu, Arda Çeti̇nkaya, Bi̇lgen Bi̇lge Geçki̇nli̇, Hasan Şi̇mşek, Oya Demi̇rci̇

Turkish Journal of Medical Sciences

Background/aim: Neural tube defects (NTDs) are common congenital malformations that develop as a result of interactions between several genes and environmental factors. Many factors have been investigated in order to understand the etiology of NTDs, and many studies have identified folate intake as a common contributing factor. The exact etiology of the disease is still unknown. Materials and methods: In this study, we compared serum folate, vitamin B12, and homocysteine levels, along with common thrombophilia-related genetic variations, including factor V Leiden, factor II g.20210G>A, MTHFR c.677C>T, and MTHFR c.1298A>C, in 35 pregnant women with fetal NTDs and …

Nail Changes In Patients With Inflammatory Bowel Diseases, Özlem Eki̇z, Ebru Çeli̇k, İlknur Balta, Bi̇lge Bülbül Şen, Emi̇ne Nur Ri̇fai̇oğlu, Mehmet Demi̇r, Fuat Eki̇z, Ömer Başar, Osman Yüksel

Turkish Journal of Medical Sciences

Background/aim: Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. To our knowledge, no studies to date pertain to the profile of nail changes in IBD, except for onychomycosis. We aimed to study the frequency and pattern of nail changes among patients with IBD and evaluate their potential relationships with several parameters in IBD. Materials and methods: The study included 73 patients with IBD and 51 healthy control subjects. Nails of both groups were examined for changes with regard to color, striations, texture, curvature of nail plates, dystrophy of nail plates, and pigmentation. …

Traditional Practices Of Konya Women During Pregnancy, Birth, The Postpartumperiod, And Newborn Care, Berri̇n Okka, Yasemi̇n Durduran, Nesli̇han Değerli̇ Kodaz

Turkish Journal of Medical Sciences

Background/aim: The purpose of the present study was to identify traditional practices and the extent to which they are practiced by mothers during pregnancy, birth, the postpartum period, and newborn care. Materials and methods: This study was conducted in the city center of Konya (Turkey). Data were collected through questionnaires completed by volunteers. The research sample comprised 450 mothers, all of whom had given birth to at least one live baby. The forms were completed during face-to-face interviews. Results: Some traditional pregnancy practices were followed by 70.7% of the participants. Of the women who performed these practices, 57.4% consciously chose …

Comparison Between The Protective Effects Of Vitamin K And Vitamin A On The Modulation Of Hypervitaminosis D3 Short-Term Toxicity In Adult Albino Rats, Said Said Elshama, Hosam-Eldin Hussein Osman, Ayman El-Meghawry El-Kenawy, Hamdi Mohamed Youseef

Turkish Journal of Medical Sciences

Background/aim: Vitamin D3 has increased risk of toxicity due to its common use in multivitamin preparations. Vitamin K and vitamin A play an important role in vitamin D action. The goal of the current study was to compare the protective effects of vitamin K and vitamin A on the modulation of hypervitaminosis D3 toxicity in rats by assessing serum calcium, renal function tests, cardiac enzymes, and related histopathological changes. Materials and methods: Eighty adult albino rats were divided into four groups; each group consisted of 20 rats. The first group received water; the second received a toxic dose of vitamin …

The Protective Effect Of Capparis Ovata In Acute Hepatotoxicity Induced By Paracetamol, Nurcan Doğan, Mustafa Akçam, Tuğba Koca, Duygu Kumbul Doğuç, Meltem Özgöçmen

Turkish Journal of Medical Sciences

Background/aim: To investigate the efficiency of Capparis ovata as a protective agent against acute paracetamol toxicity of the liver. Materials and methods: A total of 36 Wistar albino rats were divided into 4 groups: 1) paracetamol, 2) Capparis ovata + paracetamol, 3) Capparis ovata, and 4) control. Groups 2 and 3 were given Capparis ovata and Groups 1 and 4 distilled water for 8 days. On day 8, 3000 mg kg-1 paracetamol was administered orally to Groups 1 and 2. Samples were taken on day 9. AST, ALT, total bilirubin, direct bilirubin, GGT, and ALP levels were assessed. Lipid peroxidation …

Celiac Disease In Children With Chronic Constipation, Murat Çakir, Seçi̇l Cezaroğlu, Ümi̇t Çobanoğlu

Turkish Journal of Medical Sciences

Background/aim: Chronic constipation (CC) and celiac disease (CD) are the most common conditions encountered in pediatric gastroenterology. The association of these two disorders has not been evaluated properly. We analyzed the prevalence and outcome of CD in children with CC. Materials and methods: The study included children with CC (n = 313) and healthy children (n = 990). Serum IgA and IgA antitissue transglutaminase antibodies (IgA-tTG) were studied in all subjects. Intestinal biopsy and HLA-DQ2/DQ8 typing was performed in subjects with elevated IgA-tTG. Results: Serology was positive in 8 children (2.5%) with CC and 6 children (0.6%) from the control …

The Antioxidant And Antimutagenic Activities Of Ankaferd Blood Stopper,A Natural Hemostatic Agent Used In Dentistry, Aysel Uğur, Nurdan Saraç, Di̇lek Aynur Çankal, Murat Özle

Turkish Journal of Medical Sciences

Background/aim: This study investigated the antioxidant and antimutagenic properties of Ankaferd blood stopper (ABS), a plant-based topical hemostatic agent used in Turkey to treat external hemorrhages and bleeding during dental surgery. While previous studies have examined the antimicrobial, antiinflammatory, and anticarcinogenic properties of ABS, to our knowledge, this is the first study to report on the antioxidant and antimutagenic activities of this drug. Materials and methods: Antioxidant activity was evaluated using DPPH radical-scavenging and β-carotene-linoleic acid tests. Antimutagenic activity was assessed using the Ames Salmonella/microsome mutagenicity test with the bacterial mutant strains Salmonella typhimurium TA98 and TA100. Results: Although ABS …

Depression, Anxiety, And Their Relation With Clinical Parametersand Androgen Levels In Hirsute Women, Leyla Irak, Hali̇se Çinar Yavuz, Berçem Ayçi̇çek Doğan, Türkan Mete, Di̇lek Berker, Serdar Güler

Turkish Journal of Medical Sciences

Background/aim: The purpose of this study was to assess the prevalence of anxiety and depression among patients with hirsutism and to evaluate the relationships of anxiety and depression with clinical parameters and androgen levels. Materials and methods: One hundred and seven women with hirsutism were enrolled in the study. All participants completed standardized questionnaires to assess depression (Beck Depression Inventory (BDI)) and anxiety (Beck Anxiety Inventory (BAI)). The Ferriman-Gallwey (FG) scores, body mass indexes (BMIs), homeostatic model assessments of insulin resistance (HOMA-IR), and serum androgen levels of all patients were obtained. Results: Seventy-four of the 107 patients (69.15%) had BDI …

2016 Interior Least Tern And Piping Plover Monitoring, Research, Management, And Outreach Report For The Lower Platte River, Nebraska, Mary Bomberger Brown, Lauren R. Dinan

School of Natural Resources: Faculty Publications

This document reports on our monitoring, research, management, and outreach activities during the past 12 months (2015 – 2016). We prepared it to inform our partners, cooperating agencies, funding sources, and other interested parties of our activities and to provide a preliminary summary of our results.

The data, data analyses, results, summaries, and interpretations found in this document are not final and should be considered as such when being cited or referred to in documents, reports, proposals, or presentations. Please contact us before using any of this material and for additional information that may be available.

In an effort to …

American Agribusiness & Biotechnology: A New Era Of Farming, Nicole M. Ryan

Honors Undergraduate Theses

In the past fifty years there has been an incredible amount of change made to the agrarian system of the United States. New discoveries in the realm of biotechnology led to the adoption of genetically modified organisms (GMOs) in agriculture, and transformed the industry. Due to regulatory policies set during the nineteen-eighties this technology was able to benefit from widespread commercialization.

Today, we see the effects of this approach and are entering into a highly volatile political climate in regard to GMOs. This paper aims to provide an analysis of the regulatory system in place and the discrepancies that exist …