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Gene Expression Microarray Data From Human Microvascular Endothelial Cells Supplemented With A Low Concentration Of Niacin, Nica M. Borradaile, Jennifer M. Hughes-Large

Physiology and Pharmacology Publications

The systemic lipid modifying drug, niacin, can directly improve human microvascular endothelial cell angiogenic function under lipotoxic conditions, possibly through activation of niacin receptors [1]. Here we provide accompanying data collected using Affymetrix GeneChip microarrays to identify changes in gene expression in human microvascular endothelial cells treated with 10 μM niacin. Statistical analyses of robust multi-array average (RMA) values revealed that only 16 genes exhibited greater than 1.3-fold differential expression. Of these 16, only 5 were identified protein coding genes, while 3 of the remaining 11 genes appeared to be small nuclear/nucleolar RNAs. Altered expression of EFCAB4B, …

Structural And Evolutionary Analyses Show Unique Stabilization Strategies In The Type Iv Pili Of Clostridium Difficile, Kurt H. Piepenbrink, Grace A. Maldarelli, Claudia F. Martinez De La Pena, Tanis C. Dingle, George L. Mulvey, Amanda Lee, Erik Von Rosenvinge, Glen D. Armstrong, Michael S. Donnenberg, Eric J. Sundberg

Food for Health: Publications

Type IV pili are produced by many pathogenic Gram-negative bacteria and are important for processes as diverse as twitching motility, biofilm formation, cellular adhesion and horizontal gene transfer. However, many Gram-positive species, including C. difficile, also produce Type IV pili. Here, we identify the major subunit of the Type IV pili of C. difficile, PilA1, and describe multiple three-dimensional structures of PilA1, demonstrating the diversity found in three strains of C. difficile. We also model the incorporation of both PilA1 and a minor pilin, PilJ, into the pilus fiber. Although PilA1 contains no cysteine residues, and therefore cannot form the …

Fixing Published Research Mistakes Not Easy; Fixing The Publishing System May Be Harder, Alicia Rohan

Browse All News

No abstract provided.

Estimates Of The Quality Of Complementary Feeding Amongvietnamese Infants Aged 6-23months Varied By Howcommercial Baby Cereals Were Classified In 24-H Recalls, Nguyen T. Tuan, Mellissa Withers, Edward A. Frongillo Jr., Nemat Hajeebhoy

Faculty Publications

The World Health Organization's (WHO) standardized questionnaire for assessing infant and young child feeding practices does not include commercial baby cereals (CBC), which are derived from several food groups and are fortified with micronutrients. We examined how different scenarios for classifying CBC affect estimates of the quality of complementary feeding in children ages 6−23 months in Vietnam in 2014 (n = 4811). In addition to the WHO standardized 24‐h recall questionnaire for infant and young child feeding, we asked mothers about the consumption of CBC. The five resulting scenarios were S1 – omitted CBC; S2 – CBC classified as grains; …

Volume 53, Number 25: February 03, 2016, University Of North Dakota

University Letter Archive

No abstract provided.

Chronic Treatment With A Carbon Monoxide Releasing Molecule Reverses Dietary Induced Obesity In Mice, Peter Hosick, Abdulhadi A. Alamodi, Michael W. Hankins, David E. Stec

Department of Exercise Science and Physical Education Scholarship and Creative Works

ABSTRACT: Chronic, low level treatment with a carbon monoxide releasing molecule (CO-RM), CORM-A1, has been shown to prevent the development of obesity in response to a high fat diet. The objective of this study was to test the hypothesis that chronic, low level treatment with this CO-RM can reverse established obesity via a mechanism independent of food intake. Dietary induced obese mice were treated with CORM-A1, the inactive compound iCORM-A1, or saline every 48 hours for 30 weeks while maintained on a high fat (60%) diet. Chronic treatment with CORM-A1 resulted in a 33% decrease from initial body weight over …

Blockade Of Astrocytic Calcineurin/Nfat Signaling Helps To Normalize Hippocampal Synaptic Function And Plasticity In A Rat Model Of Traumatic Brain Injury, Jennifer L. Furman, Pradoldej Sompol, Susan D. Kraner, Melanie M. Pleiss, Esther J. Putman, Jacob Dunkerson, Hafiz Mohmmad Abdul, Kelly N. Roberts, Stephen William Scheff, Christopher M. Norris

Pharmacology and Nutritional Sciences Faculty Publications

Increasing evidence suggests that the calcineurin (CN)-dependent transcription factor NFAT (Nuclear Factor of Activated T cells) mediates deleterious effects of astrocytes in progressive neurodegenerative conditions. However, the impact of astrocytic CN/NFAT signaling on neural function/recovery after acute injury has not been investigated extensively. Using a controlled cortical impact (CCI) procedure in rats, we show that traumatic brain injury is associated with an increase in the activities of NFATs 1 and 4 in the hippocampus at 7 d after injury. NFAT4, but not NFAT1, exhibited extensive labeling in astrocytes and was found throughout the axon/dendrite layers of CA1 and the dentate …

Pdip46 (Dna Polymerase Delta Interacting Protein 46) Is An Activating Factor For Human Dna Polymerase Delta, Xiaoxiao Wang, Sufang Zhang, Rong Zheng, Fu Yue, Szu Hua Sharon Lin, Amal Rahmeh, Ernest Y C Lee, Zhongtao Zhang, Marietta Y W T Lee

NYMC Faculty Publications

PDIP46 (SKAR, POLDIP3) was discovered through its interaction with the p50 subunit of human DNA polymerase δ (Pol δ). Its functions in DNA replication are unknown. PDIP46 associates with Pol δ in cell extracts both by immunochemical and protein separation methods, as well as by ChIP analyses. PDIP46 also interacts with PCNA via multiple copies of a novel PCNA binding motif, the APIMs (AlkB homologue-2 PCNA-Interacting Motif). Sites for both p50 and PCNA binding were mapped to the N-terminal region containing the APIMs. Functional assays for the effects of PDIP46 on Pol δ activity on singly primed ssM13 DNA templates …

The Malleability Of University Students' Beliefs, Values, And Attitudes In The Classroom Setting, Glory Emmanuel

Psychology ETDs

Beliefs, values, and attitudes (BVAs) are central to a persons identity and worldview but can be refined and influenced through the individual's surrounding environment and experience. The academic setting is one environment that impacts BVAs. This study examined if university students' BVAs are influenced over a semester by students' attributes, their professor, and the classroom context by testing three main hypotheses: 1) students demonstrate BVA change over time while professors' BVAs remain relatively stable over time; 2) students' attributes influence BVA change; and 3) students, especially those who have a positive experience in the class, assimilate to their professor's BVAs. …

Independent - Feb., 2, 2016, Rut Ortiz

The Independent (1988-present)

No abstract provided.

The Current Volume 26 : Issue 18, Nova Southeastern University

Student Newspapers

No abstract provided.

Genome Assembly And Geospatial Phylogenomics Of The Bed Bug Cimex Lectularius, Jeffrey A. Rosenfeld, Darryl Reeves, Mercer R. Brugler, Apurva Narechania, Sabrina Simon, Russell Durrett, Jonathan Foox, Kevin Shianna, Michael C. Schatz, Jorge Gandara, Ebrahim Afshinnekoo, Ernest T. Lam, Alex R. Hastie, Saki Chan, Han Cao, Michael Saghbini, Alex Kentsis, Paul J. Planet, Vladyslav Kholodovych, Michael Tessler, Richard Baker, Rob Desalle, Louis N. Sorkin, Sergios-Orestis Kolokotronis, Mark E. Siddall, George Amato, Christopher E. Mason

Publications and Research

The common bed bug (Cimex lectularius) has been a persistent pest of humans for thousands of years, yet the genetic basis of the bed bug’s basic biology and adaptation to dense human environments is largely unknown. Here we report the assembly, annotation and phylogenetic mapping of the 697.9-Mb Cimex lectularius genome, with an N50 of 971 kb, using both long and short read technologies. A RNA-seq time course across all five developmental stages and male and female adults generated 36,985 coding and noncoding gene models. The most pronounced change in gene expression during the life cycle occurs after feeding on …

Effects Of Exercise On Food-Related Cognition, Tyshae Davis, Michael J. Larson

Journal of Undergraduate Research

Since the Yerkes-Dodson theory was initially put forward (as early as 1906), multiple theorists have suggested an inverted-U relationship between physiological arousal and cognitive performance. Literature on this topic, however, is mixed, with some studies showing evidence supporting the inverted-U relationship and others showing a more linear relationship. Exercise and food-related cognition is one area where the inverted-U hypothesis could be applied. Some studies have shown that high-intensity exercise induces an acute, but temporary suppression to hunger and energy intake compared to low-intensity exercise (King, Tremblay, & Blundell, 1997) and that high-intensity exercise favors negative energy balance to a greater …

Impact Of Meal Frequency On Appetite And Blood Markers Of Health In Obese Women Utilizing An Equi-Hypocaloric Diet During A Behavioral Weight Loss Intervention, Michelle Kulovitz

Health, Exercise, and Sports Sciences ETDs

Background: Obesity prevalence is a global pandemic and a public health concern. Beneficial weight loss strategies are needed for obesity management. Increased daily meal frequency (MF) is often associated with improvements in blood-markers of health and appetite control during weight loss; however, this has not been confirmed using portion-controlled meal products to reduce underreporting error. Objective: The purpose of this study was to determine if increased MF can be a beneficial treatment strategy for weight loss in obese women by determining the changes of total ghrelin, blood glucose, insulin, lipid concentrations, and sensations of hunger and satiety due to an …

Outcomes Of Cardiopulmonary Resuscitation And Estimation Of Healthcare Costs In Potential ‘Do Not Resuscitate’ Cases, Akhwand S. Ahmad, Sayed Mudasser, Muhammad N. Abdoun, Hafiz Nh

Sultan Qaboos University Medical Journal

Objectives: Cardiopulmonary resuscitation (CPR) is a life-saving procedure which may fail if applied unselectively. ‘Do not resuscitate’ (DNR) policies can help avoid futile life-saving attempts among terminally-ill patients. This study aimed to assess CPR outcomes and estimate healthcare costs in potential DNR cases. Methods: This retrospective study was carried out between March and June 2014 and included 50 adult cardiac arrest patients who had undergone CPR at Sultan Qaboos Hospital in Salalah, Oman. Medical records were reviewed and treating teams were consulted to determine DNR eligibility. The outcomes, clinical risk categories and associated healthcare costs of the DNR candidates were …

Modeling Food Security, Energy, And Climate And Cultural Impacts Of A Process: The Case Study Of Shea Butter In Sub-Saharan Africa, Colleen Claire Naughton

USF Tampa Graduate Theses and Dissertations

Millions of people in the world, particularly women and people in sub-Saharan Africa, suffer from hunger and poverty. Three of the major 2015-2030 United Nation’s Sustainable Development Goals (SDGs) aim to eliminate hunger through food security and sustainable agriculture, eradicate poverty, and achieve gender equality through women’s empowerment. Shea trees and their associated fruit and butter can play a major role in each of these three SDGs for women and their families throughout sub-Saharan Africa. Shea trees are located over a wide expanse stretching more than 5,000 kilometers across over eighteen countries in sub-Saharan Africa. These trees produce fruit that …

"A Certain Kind Of Light": Adjunct Professor Keith Wakefield Produces Award-Winning Film, Samuel Fry

Andrews Agenda: Campus News

No abstract provided.

Complete Volume (46)

Speaker & Gavel

Complete digitized volume (volume 46) of Speaker & Gavel.

Superman And Wonder Woman: French Champions For Hiv/Aids Prevention Of Failed Aids Campaign?, Stephen M. Croucher, Terry L. Rentner

Speaker & Gavel

In 2004, the French government sponsored an AIDS/HIV prevention campaign; AIDES.ORG using photos of AIDS infected Superman and Wonder Woman to persuade adolescents to adopt preventative behaviors. This article asserts campaign organizers cancelled the campaign because it failed to provide audience efficacy and incorrectly manipulated fear in its campaign messages. Moreover, this article compares the AIDES.ORG campaign to other AIDS/HIV campaigns and argues effective health communication campaigns must provide efficacy to facilitate adoption of desired preventative behaviors. The Social Norms Approach is offered as an alternative method for developing effective health communication campaigns.

Lanthorn, Vol. 50, No. 38, February 1, 2016, Grand Valley State University

Volume 50, July 13, 2015 - June 6, 2016

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Keynoter, February/March 2016, Boise State University Association Of Office Professionals

Boise State University Association of Office Professionals - Keynoter

President’s Message

AOP Purpose

February Brown Bag

IAEOP Conference

January Brown Bag Recap

Book Club: Michael Weitz

Holiday Auction

10 Ways You Can “Connect, Join, Thrive

Rene’ Delaney—Higher Educational National Council Chair/NAEOP

Membership

PSP Standards

List & Calendar of Events

Calendar

Possible Orthologs Of Trpa And Trpb Genes Between E. Coli (B1260 And B1261) And M. Ruber (Mrub_1512 And Mrub_1511), John J. Stenger, Dr. Lori Scott

Meiothermus ruber Genome Analysis Project

Mrub_1512 encodes the enzyme tryptophan A (DNA coordinates 1544300..1545091), which is the 6th step of the Tryptophan Biosynthesis pathway (KEGG map number 00400). It catalyzes the conversion of Chorismate to L-Tryptophan. The E. coli K12 MG1655 ortholog is predicted to be b1260, which has the gene identifier trpA. We predict that Mrub_1512 (DNA coordinates 1544300..1545091) is a alpha subunit of the Tryptophan Synthase (KEGG map number 00400). Mrub_1511 encodes the enzyme tryptophan B (DNA coordinates 1543083..1544303), which is the 7th step of the Tryptophan Biosynthesis pathway (KEGG map number 00400). It catalyzes the conversion of Chorismate to L-Tryptophan. The E. …

Come And “Take” It: Whooping Cranes, Texas Water Rights, Endangered Species Act Liability, And Reconciling Ecological Scientific Testimony Within The Context Of Proximate Causation, Brett A. Miller

Student Scholarship

Tension between science and the law is a pervading feature of Endangered Species Act (ESA) jurisprudence. Incorporating the scientific discipline of ecology within the legal landscape presents distinct challenges, particularly in comparison with more traditional laboratory sciences. Within the realm of Endangered Species Act liability, the intricacies of nature exacerbate already complicated links of causation, challenging the ability to prove violations of the “take” prohibition. Because uncertainties permeate scientists’ ability to understand complex ecosystem processes, courts should rely on the overarching practicality of common law principles when reviewing ecological testimony.

When evaluating claims that allege violations of the “take” prohibition, …

Forging Links Between Food Chain Labor Activists And Academics, Laura-Anne Minkoff-Zern, Jennifer Gaddis, Nathan Mcclintock, Joann Lo, Felipe Tendick-Matesanz, Amy K. Coplen, Anelyse M. Weiler

Food Studies - All Scholarship

Interest in food movements has been growing dramatically, but until recently there has been limited engagement with the challenges facing workers across the food system. Of the studies that do exist, there is little focus on the processes and relationships that lead to solutions. This article explores ways that community-engaged teaching and research partnerships can help to build meaningful justice with food workers. The text builds on a special roundtable session held at the Annual Meeting of the American Association of Geographers in Chicago in April 2015, which involved a range of academic scholars and community-based activists. We present these …

The Baysider : February 2016, Bayside Neighborhood Association

The Baysider

The Baysider (1999 - 2018) a community newspaper, published by the Bayside Neighborhood Association. Bayside is an inner-city Portland neighborhood flanked by Parkside, Back Cove, Downtown (a.k.a. Intown), and the East End. Feature articles focused on Bayside, though also included many city themes.

Los Baños Times, Vol. 36, No. 2, College Of Development Communication, University Of The Philippines Los Baños

Los Baños Times

No abstract provided.

Cpaf Updates Vol. 17 Issue No. 2, Francisca O. Tan, Stella Concepcion R. Britanico, Cristeta A. Foronda

CPAf Updates

In this issue:

• Dr. Cardenas in new CPAf Dean, 1
• CPAf holds its 18th anniversary celebration, 2
• CPAf co-sponsors memorial lecture for Jesse M. Robredo, 3
• Deputy Ombudsman Mosquera talks on fighting corruption, 3
• CISC and IGRD welcome new staff, 4

Geography Newsletter, Department Of Geography

Geography Newsletter

Contents:
Head’s Column [Page] 2
Dr. Lin Visits China [Page] 3
Field Research in Portugal [Page] 3
Return to Romania [Page] 4
Excursion to Cuba [Page] 4
Students Visit Jerry Wilson’s Eco-Friendly Solar House [Page] 5
GIS at St. Francis Indian School [Page] 5
Great Plains- Rocky Mountain Division Meeting [Page] 6
Kearney Field Excursion [Page] 6
Gamma Theta Upsilon (GTU): Delta Zeta (DZ) [Page] 6
Geography Awareness Week (GAW) Speaker [Page] 7
SDGA Promotes GAW [Page] 7
Cole Krehbiel Wins Prestigious Award [Page] 8
Delora Bennett: Employee of the Month [Page] 8
Graduate Student and Alumnae Add Depth to …

Isu Today - February 28, 2016 - Sherard Clinkscales, Indiana State University, Communications And Marketing

University Announcements - ISU Today

No abstract provided.

Chronic Consumption Of A Western Diet Induces Robust Glial Activation In Aging Mice And In A Mouse Model Of Alzheimer’S Disease, Leah C. Graham, Jeffrey M. Harder, Ileana Soto Reyes, Wilhelmine N. De Vries, Simon W. M. John, Gareth R. Howell

College of Science & Mathematics Departmental Research

Studies have assessed individual components of a western diet, but no study has assessed the long-term, cumulative effects of a western diet on aging and Alzheimer’s disease (AD). Therefore, we have formulated the first western-style diet that mimics the fat, carbohydrate, protein, vitamin and mineral levels of western diets. This diet was fed to aging C57BL/6J (B6) mice to identify phenotypes that may increase susceptibility to AD, and to APP/PS1 mice, a mouse model of AD, to determine the effects of the diet in AD. Astrocytosis and microglia/monocyte activation were dramatically increased in response to diet and was further increased …