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Research News Newsletter, Fall 2016, Research News Newsletter, Stony Brook University.

Research News

Quarterly newsletter from the Office of the Vice President for Research

College Of Health Sciences Newsletter, September 2016, Irvin B. Harrell (Editor)

Ellmer College of Health Sciences Newsletters

September 2016 issue of Old Dominion University's College of Health Sciences Newsletter.

Wealth And Poverty | Week Current Issues In Global Health, Sept. 28, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Or Traffic: Summary, Children's Mercy Kansas City

Patient Safety Critically Appraised Topics

No abstract provided.

Impact Of Flood On Rural Population And Strategies For Mitigation: A Case Study Of Darbhanga District, Bihar State, India, Vikash Kumar, Suk Yin Caroline Cheng, Ajit Kumar Singh

Contemporary Rural Social Work Journal

Floods are one of the most disastrous acts of nature and impact human life in multiple ways. Damages by floods in rural areas are more severe compared to urban counterparts due to poverty, limited infrastructures and access to resources and health care services. The Province of Bihar in India, with a population of 104.1 million, has 76 per cent of the population living under recurring threat of floods. In 2008, Bihar experienced severe floods in the northern region that affected more than 2.3 million people; and in 2013, they affected more than 5.9 million in 3768 villages across 20 rural …

Impact Of A Telehealth Program That Delivers Remote Consultation And Longitudinal Mentorship To Community Hiv Providers, Brian R. Wood, Kenton T. Unruh, Natalia Martinez-Paz, Mary Annese, Christian B. Ramers, Robert D. Harrington, Shireesha Dhanireddy, Lisa Kimmerly, John D. Scott, David H. Spach

Project ECHO Bibliography

Background. To increase human immunodeficiency virus (HIV) care capacity in our region, we designed a distance mentorship and consultation program based on the Project ECHO (Extension for Community Healthcare Outcomes) model, which uses real-time interactive video to regularly connect community providers with a multidisciplinary team of academic specialists. This analysis will (1) describe key components of our program, (2) report types of clinical problems for which providers requested remote consultation over the first 3.5 years of the program, and (3) evaluate changes in participants' self-assessed HIV care confidence and knowledge over the study period. Methods. We prospectively tracked types of …

Soci 270.01: Introduction To Development Sociology, Teresa R. Sobieszczyk

University of Montana Course Syllabi, 2016-2020

No abstract provided.

Exploring Determinants Of Handwashing With Soap In Indonesia: A Quantitative Analysis, Mitsuaki Hirai, Jay P. Graham, Kay Mattson, Andrea Kelsey, Supriya Mukherji, Aidan Cronin

Environmental and Occupational Health Faculty Publications

Handwashing with soap is recognized as a cost-effective intervention to reduce morbidity and mortality associated with enteric and respiratory infections. This study analyzes rural Indonesian households’ hygiene behaviors and attitudes to examine how motivations for handwashing, locations of handwashing space in the household, and handwashing moments are associated with handwashing with soap as potential determinants of the behavior. The analysis was conducted using results from a UNICEF cross-sectional study of 1700 households in six districts across three provinces of Indonesia. A composite measure of handwashing with soap was developed that included self-reported handwashing, a handwashing demonstration, and observed handwashing materials …

Gene Duplication And Divergence Produce Divergent Mhc Genotypes Without Disassortative Mating, Donald C. Dearborn, Andrea B. Gager, Andrew G. Mcarthur, Morgan E. Gilmour, Elena Mandzhukova, Robert A. Mauck

All Faculty Scholarship

Genes of the major histocompatibility complex (MHC) exhibit heterozygote advantage in immune defence, which in turn can select for MHC-disassortative mate choice. However, many species lack this expected pattern of MHC-disassortative mating. A possible explanation lies in evolutionary processes following gene duplication: if two duplicated MHC genes become functionally diverged from each other, offspring will inherit diverse multilocus genotypes even under random mating. We used locus-specific primers for high-throughput sequencing of two expressed MHC Class II B genes in Leach's storm-petrels, Oceanodroma leucorhoa, and found that exon 2 alleles fall into two gene-specific monophyletic clades. We tested for disassortative vs. …

High Correlation Of Middle East Respiratory Syndrome Spread With Google Search And Twitter Trends In Korea, Soo-Yong Shin, Dong-Woo Seo, Jisun An, Haewoon Kwak, Sung-Han Kim, Jin Gwack, Min-Woo Jo

Research Collection School Of Computing and Information Systems

The Middle East respiratory syndrome coronavirus (MERS-CoV) was exported to Korea in 2015, resulting in a threat to neighboring nations. We evaluated the possibility of using a digital surveillance system based on web searches and social media data to monitor this MERS outbreak. We collected the number of daily laboratory-confirmed MERS cases and quarantined cases from May 11, 2015 to June 26, 2015 using the Korean government MERS portal. The daily trends observed via Google search and Twitter during the same time period were also ascertained using Google Trends and Topsy. Correlations among the data were then examined using Spearman …

Survival Of High-Risk Pediatric Neuroblastoma Patients In A Developing Country, Joseph C. Easton, Sergio Gomez, Peter H. Asdahl, J. Michael Conner, Alcira B. Flynn, Claudia Ruiz, Rohit P. Ojha

Faculty Publications

Little information is available about survival of high‐risk pediatric neuroblastoma patients in developing countries. We aimed to assess survival among high‐risk pediatric neuroblastoma patients in La Plata, Argentina. Individuals eligible for our cohort were aged4 yr at diagnosis, 54% were male, and 62% had adrenal neuroblastoma. We observed 18 deaths, and the median survival time of our study population was 1.7 yr. The five‐yr overall survival probability was 24% (95% CL: 10%, 41%). In contrast, five‐yr survival of high‐risk neuroblastoma patients ranges between 23% and 76% in developed countries. Survival among high‐risk neuroblastoma patients is generally poor regardless of geographic …

Burden Of Diabetes Mellitus And Role Of Telemedicine In Its Management: Narrative Review, Gulshan Bano, Savera Aziz Ali, Minaz Mawani, Sumera Aziz Ali

Section of Diabetes, Endocrinology and Metabolism

Objective: The purpose of this review is to summarize the findings regarding the prevalence and risk factors of Diabetes Mellitusin developed and developing world and to review the management options for Diabetes Mellitus especially the role of telemedicine.

Methodology: Extensive literature review was carried by retrieving articles from various databases like Pub med, Google scholar, Science direct, Scopus and Archives of Medicine. Relevant articles were retrieved from different databases by using text words and phrases like ‘Diabetes Mellitus’, ‘Management’, ‘risk factors’, ‘prevalence of Diabetes’, ‘telemedicine’, ‘e- health’. Types of studies were descriptive studies, systematic reviews and various reports. …

Rrh Library Newsletter, September 2016, Libraries At Rochester Regional Health

Rochester Regional Health authored publications and proceedings

Newsletter sections include: Culture of Safety; Dangers of Sitting; Used Book Sale

Database Spotlight: Nursing Fall 2016, The University Of Alabama In Huntsville

Database Spotlight

No abstract provided.

The Macroecology Of Infectious Diseases: A New Perspective On Global-Scale Drivers Of Pathogen Distributions And Impacts, Patrick R. Stephens, Sonia Altizer, Katherine F. Smith, A. Alonso Aguirre, James H. Brown, Sarah A. Budischak, James E. Byers, Tad A. Dallas, T. Jonathan Davies, John M. Drake, Vanessa O. Ezenwa, Maxwell J. Farrell, John L. Gittleman, Barbara A. Han, Shan Huang, Rebecca A. Hutchinson, Pieter Johnson, Charles L. Nunn, David Onstad, Andrew Park, Gonzalo M. Vazquez-Prokopec, John P. Schmidt, Robert Poulin

Faculty Publications

© 2016 John Wiley & Sons Ltd/CNRS. Identifying drivers of infectious disease patterns and impacts at the broadest scales of organisation is one of the most crucial challenges for modern science, yet answers to many fundamental questions remain elusive. These include what factors commonly facilitate transmission of pathogens to novel host species, what drives variation in immune investment among host species, and more generally what drives global patterns of parasite diversity and distribution? Here we consider how the perspectives and tools of macroecology, a field that investigates patterns and processes at broad spatial, temporal and taxonomic scales, are expanding scientific …

The End Of The Wormwars?, David Tovey, Julia H. Littell, Jeremy M. Grimshaw

Graduate School of Social Work and Social Research Faculty Research and Scholarship

No abstract provided.

Experimental Infection Of Conventional Nursing Pigs And Their Dams With Porcine Deltacoronavirus, Sarah Vitosh-Sillman, John Dustin Loy, Bruce W. Brodersen, Clayton L. Kelling, Alan R. Doster, Christina L. Topliff, Eric A. Nelson, Jianfa Bai, Erin Schirtzinger, Elizabeth Poulsen, Barbara Meadors, Joseph Anderson, Benjamin Hause, Gary Anderson, Richard Hesse

School of Veterinary and Biomedical Sciences: Faculty Publications

Porcine deltacoronavirus (PDCoV) is a newly identified virus that has been detected in swine herds of North America associated with enteric disease. The aim of this study was to demonstrate the pathogenicity, course of infection, virus kinetics, and aerosol transmission of PDCoV using 87 conventional piglets and their 9 dams, including aerosol and contact controls to emulate field conditions. Piglets 2–4 days of age and their dams were administered an oronasal PDCoV inoculum with a quantitative real-time reverse transcription (qRT)-PCR quantification cycle (Cq) value of 22 that was generated from a field sample having 100% nucleotide identity to USA/Illinois121/2014 determined …

Genetic Amplification: Quantitative Polymerase Chain Reaction And Its Problems And Uses, Drew Mcwilliams

Honors Projects

Quantitative polymerase chain reaction (qPCR), also called real-time PCR, has become a cornerstone of DNA analysis, enabling detection of minute amounts of nucleic acids (Whittwer et. al, 1997). In 1983, Kary Mullis developed a new method of genetic amplification—the polymerase chain reaction [PCR] (Bartlett & Stirling, 2003). A little over 20 years later, PCR now is a common and often crucial technique used in medical and biological research laboratories for a variety of applications. Some of these applications include DNA cloning for sequencing, DNA-based phylogeny, the diagnosis of hereditary diseases, the identification of genetic fingerprints (used in forensic sciences and …

Identification Of Nonalcoholic Fatty Liver Disease In Patients With Hepatitis C: Using Evidence Based Guidelines To Improve Diagnosis And Transition Of Care From Specialty Care Provider To Primary Care Provider, Debra B. Bayus

Doctoral Projects

Chronic liver disease is a process that involves progressive destruction and regeneration of the liver causing fibrosis, cirrhosis and hepatocellular carcinoma, and early death. Persons with chronic liver disease treated for hepatitis C with abnormal radiological imaging consistent with increased fat content in the liver (hepatic steatosis) should be evaluated for nonalcoholic fatty liver disease (NAFLD). However, individuals treated at a community hepatitis C treatment clinic are currently not being evaluated for NAFLD. In addition, if NAFLD is diagnosed, management of these co-occurring conditions is required to delay disease progression. Factors contributing to gaps in NAFLD care include: poor communication, …

Psci 337.01: Model United Nations, Nicholas Potratz

University of Montana Course Syllabi

No abstract provided.

Gbld 194.04: Reimagining Global Health - Biosocial Perspectives, Gilbert Quintero

University of Montana Course Syllabi

No abstract provided.

Predictive Model For Blood Product Use In Coronary Artery Bypass Grafting, Hasanat Sharif, Hamza Zaheer Ansari, Awais Ashfaq, Wasiq Faraz Rawasia, Gulshan Bano, Shiraz Hashmi

Section of Cardiothoracic Surgery

Objective: To build a clinical predictive model to determine the need for transfusing blood and its products in coronary artery bypass grafting (CABG) procedures in South East Asian population.STUDY Design: Analytical study.PLACE AND DURATION OF STUDY: Section of Cardiothoracic Surgery, Aga Khan University Hospital, Karachi, from January 2006 to October 2014.METHODOLOGY: Information on pre-, intra- and postoperative variables were collected for all adult patients who underwent on-pump CABG. The patients grouped into those who received blood and its components, and those who did not. Aunivariate as well as multivariate logistic model was built to determine the predictors of transfusion.Results: A …

Population-Based Legal Analysis: Bridging The Interdisciplinary Chasm Through Public Health In Law, Wendy E. Parmet

Journal of Legal Education

No abstract provided.

Bibliography To Current Knowledge Of Studies Of Pathogens In Colombian Mammals, Viviana Gonzalez-Astudillo, Héctor E. Ramírez-Chaves, Joerg Henning, Thomas R. Gillespie

MANTER: Journal of Parasite Biodiversity

Mammals provide an important ecological habitat or niche space to microbial diversity, protistans (or protozoans) and metazoan parasites that can have profound effects on both human and animal health. Thus, understanding the status of mammalian species as hosts for pathogens holds relevance, especially during this time of anthropogenic environmental change. Despite the great diversity in the mammal fauna of Colombia, data in the literature on the occurrence of parasites and pathogens in these mammals are scarce and widely scattered. In order to understand the state of the knowledge of pathogens carried by wild mammals in Colombia, a systematic review of …

A Pilot Study Of Sheep Disease Surveillance In Western Australia, Roy Butler

Conference papers and presentations

A pilot study of sheep disease surveillance was conducted in 2014-2015 on four farms in the eastern wheatbelt of Western Australia. The participants observed their sheep, sufficiently closely to notice disease, at least every second day. Most of the disease syndrome reports related to fewer than five sheep, demonstrating that farmers noticed problems in individual sheep, and not only in groups of sheep. Of a total of 66 disease syndrome observations reported over 12 months, the three most frequently occurring syndromes were found dead + sudden death (combined), skin lesions, and lameness.

Prevalence And Risk Factors Of Gram-Negative Bacilli Causing Blood Stream Infection In Patients With Malignancy, Fawzia E. Al-Otaibi, Elham E. Bukhari, Mona Badr, Abdulkarim A. Alrabiaa

Saudi Medical Journal

Objectives: To evaluate the epidemiology, risk factors, and antibiotic resistance of Gram negative bacteria (GNB) in patients with hematologic or solid organ malignancies. Methods: This is a retrospective study of 61 episodes of GNB bacteremia occurring in 56 patients with malignancy admitted to the Oncology Units in King Khalid University Hospital, Riyadh. Kingdom of Saudi Arabia during the period from January 2013 to October 2015. Data were retrieved from the computerized database of the microbiology laboratory and the patient’s medical records. Results: Hematological malignancies accounted for 30 (54%) and solid tumors accounted for 26 (46%). The most common hematological malignancies …

Greater New Haven Community Index 2016, Mark Abraham, Mary Buchanan

Reports

No abstract provided.

Evidence-Based Homoeopathy: A Case Of Corneal Abscess, Sandeep Sathye

Indian Journal of Research in Homoeopathy

Corneal abscess is a circumscribed collection of pus within the layers of cornea. It is usually endogenous in origin and commonly found near the limbal blood vessels close to corneal margin. Treatment in modern medicine is use of local and systemic antibiotics. Homoeopathy has mentioned medicines for corneal abscess. A case reported was a female of 68 years of age suffering from symptoms of redness, dull pain, and foreign body sensation in the right eye and was diagnosed as corneal abscess. The homoeopathic medicine Hepar sulphuris 200C was prescribed on the basis of pathology. Abscess was reduced considerably within 5 …

Antiretroviral Therapy For The Prevention Of Hiv-1 Transmission., Myron S. Cohen, Ying Q. Chen, Marybeth Mccauley, Theresa Gamble, Mina C. Hosseinipour, Nagalingeswaran Kumarasamy, James G. Hakim, Johnstone Kumwenda, Beatriz Grinsztejn, Jose H.S. Pilotto, Sheela V. Godbole, Suwat Chariyalertsak, Breno R. Santos, Kenneth H. Mayer, Irving F. Hoffman, Susan H. Eshleman, Estelle Piwowar-Manning, Leslie Cottle, Xinyi C. Zhang, Joseph Makhema, Lisa A. Mills, Ravindre Panchia, Sharlaa Faesen, Joseph Eron, Joel Gallant, Diane Havlir, Susan Swindells, Vanessa Elharrar, David Burns, Taha E. Taha, Karin Nielsen-Saines, David D. Celentano, Max Essex, Sarah E. Hudelson, Andrew D. Redd, Thomas R. Fleming

Journal Articles: Internal Medicine

BACKGROUND: An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052 trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked infections caused by human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. ART was then offered to all patients with HIV-1 infection (index participants). The study included more than 5 years of follow-up to assess the durability of such therapy for the prevention of HIV-1 transmission.

METHODS: We randomly assigned 1763 index participants to receive either early or delayed ART. In the early-ART group, 886 participants started therapy at enrollment (CD4+ count, 350 …

Acute Respiratory Distress Syndrome Complicating Community-Acquired Pneumonia Secondary To Mycobacterium Tuberculosis In A Tertiary Care Center In Saudi Arabia, Ebrahim S. Mahmoud, Salim A. Baharoon, Eiman Alsafi, Hamdan Al-Jahdali

Saudi Medical Journal

Objectives: To discuss our center’s experience with acute respiratory distress syndrome (ARDS) secondary to pulmonary tuberculosis (TB) in a major tertiary referral hospital in the Kingdom of Saudi Arabia. Methods: A retrospective review of medical records of all patients with community-acquired pneumonia secondary to mycobacterium TB infection who were admitted for critical care in a single center of King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia from 2004 to 2013. Results: In our review of 350 patients with community-acquired pneumonia admitted to Intensive Care Unit, 11 cases of TB complicated with ARDS were identified. The mean age of patients …