Digital Commons Network^™

Maternal And Newborn Health, Population Council

Momentum

IN THIS ISSUE: Building the evidence: What works to improve maternal and newborn health | Ending eclampsia: Preventing maternal death by expanding access to lifesaving interventions | Promoting respectful maternal and reproductive health care | Timely treatment for obstetric fistula: Improving maternal health outcomes | Menstrual regulation with medication: Reducing maternal mortality in Bangladesh | Saving lives: Validating indicators of the quality of maternal health care

Stress Reduction Program In A Military Clinic, Hyun-Ju Kang

Doctor of Nursing Practice Projects

Occupation-related stress has been a long-standing concern of the health care industry. Studies indicate that health care workers have higher rates of substance abuse and suicide than other professionals and elevated rates of depression and anxiety linked to job stress. In addition to psychological distress, other outcomes of job stress include burnout, absenteeism, employee intent to leave, reduced patient satisfaction, and diagnosis and treatment errors. Mindfulness interventions, such as practicing yoga on a regular basis, have been found to be effective in reducing work-related stress by multiple researchers. The overall level of stress, anxiety and depression decreased after implementation of …

Protein-Protein Interactions Of Human Mitochondrial Amidoxime-Reducing Component In Mammalian Cells, John Thomas

Electronic Theses and Dissertations

Newly discovered pterin-molybdoenzymes mammalian proteins, mARC1, and mARC2, are though to activate pro-drug, metabolize mutated base pairs, and producing nitric oxide from nitrite. However, the physiological function of the mARC proteins remain unclear. It is hypothesized that identifying partner proteins through protein-protein interactions can provide evidence to their physiological function. This study aimed to further investigate the potential function of mARC proteins through the identification of protein-protein interaction in human cell lysate, utilizing co-immunoprecipitation, crosslinking reagent, and pull-down assays. Several proteins (e.g. mitogen-activated protein kinase 5, phosphatidylinositol 4-phospahte 3-kinase C2 domain-containing subunit beta, ADP/ATP translocase 1, and myotubularin) were identified …

Prospects For Subunit Vaccines: Technology Advances Resulting In Efficacious Antigens Requires Matching Advances In Early Clinical Trial Investment, Siobhan Mcclean

Articles

With the continued march of antimicrobial resistance, a renewed impetus for better vaccines has been heralded. Identification of potent subunit vaccines has been greatly facilitated by recent developments in reverse vaccinology and proteomics strategies. There are a range of antimicrobial resistant bacterial pathogens that could be targeted by potent vaccine antigens identified within the coming years. However, cost is a significant hurdle in progressing lead antigen candidates to clinical trials. In order for novel vaccine technologies to realize their clinical potential, there is a requirement to improve investment and incentives to expedite the development of vaccines that are apparently efficacious …

Retrospective Review Of Task-Shifting Community-Based Programs Supporting Arv Treatment And Retention In Uganda, Sam Kalibala, Jerry Okal, Brady Zieman, Nrupa Jani, Lung Vu, Josephine Birungi, Stephen Okoboi, Jonathan Wangisi, Christine Nabiryo, Joanne Lyavala Okullu, Michael Etukoit, Lydia Buzaalirwa, Augustine Lubanga, Paul Kiyingi, Jonathan Ikapule, Syson Nakyeyune, Stephen Nakibinge, Penninah Lutung, Samuel Waliggo, Joseph Nsamba, Yashien Wamanga, Joseph Kamya, Robina Sentongo, Robert Yiga

HIV and AIDS

The purpose of this study was to examine examples of task-shifting programs in Uganda with the aim of generating data that could inform the development of task-shifting policies, guidelines, and practices. The overall purpose of the study was to contribute to the growing knowledge base about task-shifting by describing the service delivery approaches of three purposively selected major AIDS service organizations (ASOs) in Uganda that have adopted task-shifting. The study showed that in the three ASOs, almost all key tasks in antiretroviral therapy (ART), including determining eligibility, initiating ART, and dispensing antiretrovirals, can be feasibly shifted to lower-level cadres or …

Analyses Of Endothelial Cells And Endothelial Progenitor Cells Released Microvesicles By Using Microbead And Q-Dot Based Nanoparticle Tracking Analysis, Jinju Wang, Yun Zhong, Xiaotang Ma, Xiang Xiao, Chuanfang Cheng, Yusen Chen, Ifeanyi Iwuchukwu, Kenneth J. Gaines, Bin Zhao, Shiming Liu, Jeffrey B. Travers, Ji C. Bihl, Yanfang Chen

Pharmacology and Toxicology Faculty Publications

Accurate analysis of specific microvesicles (MVs) from biofluids is critical and challenging. Here we described novel methods to purify and detect MVs shed from endothelial cells (ECs) and endothelial progenitor cells (EPCs) by combining microbeads with fluorescence quantum dots (Q-dots) coupled nanoparticle tracking analysis (NTA). In the in vitroscreening systems, we demonstrated that 1) anti-CD105 (EC marker) and anti-CD34 (EPC marker) conjugated-microbeads had the highest sensitivity and specificity for isolating respective MVs, which were confirmed with negative controls, CD41 and CD235a; 2) anti-CD144 (EC marker) and anti-KDR (EPC marker) conjugated-Q-dots exhibited the best sensitivity and specificity for their respective …

Csusb Magazine (Fall/Winter 2015-2016), Csusb

CSUSB Magazine

Features

Pride and Pedagogy......Page 6
From CSUSB's beginnings to today, one trait has stood in relief; Great professors devoted to seeing their students succeed.

50 Big Events in CSUSB History......Page 8
Remember with CSUSB many of the people, milestones and major achievements that have shaped the stout character of the university by the hills. What was big when you were here?

Aluminati......Page 12
Fifty of CSUSB's stellar graduates and what they do.

The CSUSB Difference......Page 16
Over 50 years, the profound impact of a new college in inland Southern California is seen in the stories students …

Treatment Options For Skin And Soft Tissue Infections Caused By Methicillin-Resistant Staphylococcus Aureus, Renee Weinberg

The Science Journal of the Lander College of Arts and Sciences

Staphylococcus aureus is a pathogen responsible for common skin infections, such as impetigo, cellulitis, folliculitis, and abscess and it is the most common cause for skin and soft tissue infections (SSTI). Humans are carriers of this microorganism and are responsible for facilitating its spread around the world. Over time it has developed resistance to multiple antibiotics, such as penicillin and methicillin, which has made S. aureus a persistent problem in the healthcare world today. Its methicillin resistance has given it the more commonly known name methicillin-resistant S. aureus (MRSA). MRSA was initially discovered solely in the healthcare environment and thus …

Malignancies Associated With Inflammatory Bowel Diseases, Nicole Gong Jawitz

Yale Medicine Thesis Digital Library

Inflammatory Bowel Diseases (IBD), specifically Crohn’s disease and ulcerative colitis, have been associated with numerous intestinal and extra- intestinal malignancies. Recent studies have suggested use of immunomodulator therapies has increased risks of malignancies, including melanoma, non-epithelial skin cancers, cervical cancer, and bladder and urinary tract cancers. The question regarding how biologic agents, which became a mainstay therapy of IBD in the early 2000s, have influenced malignancy risk among patients with IBD has yet to be definitely answered.

The aims of this study were to characterize prevalence of comorbid malignancies among hospitalized patients with IBD and how it has changed over …

Apopo Annual Report 2016, Apopo

Global CWD Repository

APOPO is a global non-profit organization registered in Belgium that researches, develops and implements detection rat technology for humanitarian purposes. Detection rats, nicknamed HeroRATs, save lives by detecting landmines and tuberculosis. APOPO is headquartered in Tanzania and clears landmines in Mozambique, Angola and Cambodia, and soon in Zimbabwe. APOPO also detects tuberculosis in Tanzania and Mozambique and soon in Ethiopia. APOPO’s research and development center is based in Tanzania.

Evaluation Of Borrelia Burgdorferi Sensu Lato Seroprevalencein The Province Of Bolu, Turkey, Özlem Bucak, Mücahi̇de Esra Koçoğlu, Teki̇n Taş, Firat Zafer Mengeloğlu

Turkish Journal of Medical Sciences

Background/aim: The aim of the present study was to determine the seroprevalence of Borrelia burgdorferi sensu lato in the city center and the province of Bolu, Turkey. Materials and methods: A stratified sampling method was used to determine the study population. A total of 196 blood samples were collected. A questionnaire was completed by each participant in the study. ELISA was performed and positive serologic results were confirmed using western blotting. Data were analyzed statistically using the chi-square test. Results: Seropositivity rates of B. burgdorferi IgM and IgG were determined as 14.8% (29/196) and 13.7% (27/196) respectively by ELISA. A …

Hearing Loss Perception In Adults With Cystic Fibrosis, Bryn Pearce Spejcher

Independent Studies and Capstones

Assess the validation in perception of hearing loss in adults with cystic fibrosis using the Hearing Handicap Inventory for Adults questionnaire, a full audiological examination and affects of aminoglycosides.

Identification And Characterization Of Interactors Of Plasmodium Falciparum Pfpk6, An Atypical Protein Kinase, Andi J. Cummins

Honors Undergraduate Theses

Plasmodium falciparum, the organism that causes the most prevalent and most virulent cases of malaria in humans, poses a major health burden on the developing world, especially in the tropical regions of Sub-Saharan Africa, Southeast Asia, and Latin America. The burden of the disease is intensified by the fact that the parasite has developed widespread resistance to all current antimalarial therapies, such as chloroquine. This drug resistance underscores the need to develop novel therapeutics that target the parasite, but show low toxicity in the human host. Protein kinases, because of their integral roles in cell signaling networks, are considered to …

Tears In Heaven: Religiously And Culturally Sensitive Laws For Preventing The Next Pandemic, Eloisa Rodriguez-Dod, Aileen M. Marty, Elena Marty-Nelson

Faculty Publications

In February 2016, the World Health Organization (WHO) declared a “public health emergency of international concern” due to the increased clusters of microcephaly, Guillain-Barré Syndrome, and other neurological disorders in areas affected by the Zika virus. That declaration came in the wake of the West Africa Ebola crisis. Back to back declarations by WHO of the highest threat level for an international public health emergency underscores how quickly pathogens can now spread and cause devastation across borders. It also highlights the need to implement lessons learned from each pandemic crisis without delay. These crises demonstrate that laws to curtail the …

Graduate Catalog 2016-2017, Southwestern Oklahoma State University

Graduate Catalogs

No abstract provided.

The Trend Of Communicable And Non-Communicable Diseases In East African Community (Eac) Countries: Case Study Of Burundi, Rwanda, And Uganda - 1990 To 2013, Emile Shumbusho

Master of Public Health Program Student Publications

Background: In low and middle-income countries (LMICs), non-communicable diseases (NCDs) are rapidly emerging alongside a well-documented persistence of communicable diseases (CDs) in fragile health care systems. In sub-Saharan Africa, chronic NCDs are expected to overtake CDs as the leading cause of death. The aim of this study was to compare mortality rates due to CDs and NCDs between developed countries, developing countries, Burundi, Rwanda, and Uganda from 1990 to 2013.

Methods: A descriptive study with longitudinal and cross-sectional analyses of mortality rates was conducted using the global burden of disease (GBD) study data. Tableau Public 9.3 software was utilized to …

Alternate Routes Of Administration Among Prescription Opioid Misusers And Associations With Sexual Hiv Transmission Risk Behaviors, Mance E. Buttram, Steven P. Kurtz

CAHSS Faculty Articles

Literature suggests that young adult prescription opioid misusers who are using alternate routes of administration (e.g., snorting, injecting) may be engaging in sexual and non-sexual HIV risk behaviors. This study examines demographics, substance use, sexual risk behavior, and health and social problems associated with alternate routes of administration of prescription opioids among a sample of young adult prescription opioid misusers. Data are drawn from baseline assessments from a behavioral intervention trial. Eligible participants were ages 18–39, and reported recent (past 90 days) heterosexual sex, and recent and regular substance use and attendance at large, recognized local nightclubs. The analyses include …

Identification Of Protein-Protein Interactions Of Amyotrophic Lateral Sclerosis Associated Protein Tdp-43, Hanoor Sharma

Browse all Theses and Dissertations

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by progressive degeneration of upper and lower motor neurons in the brain and spinal cord. Multiple mutations are found in some of the proteins associated with ALS, including superoxide dismutase (SOD1), fused in sarcoma (FUS) and trans-activation response DNA-binding protein (TDP-43). TDP-43 is a DNA and RNA binding protein, well conserved, and ubiquitously expressed in all tissues. TDP-43 resides in the nucleus and sometimes shuttles between nucleus and cytoplasm. Mutations in TDP-43 leads to mislocalization of TDP-43 to the cytosol where it was ubiqutinated and hyperphosphsorylated, ultimately leading to neuronal cell …

Icipe Annual Report 2016, International Centre Of Insect Physiology And Ecology (Icipe)

icipe Annual Reports

No abstract provided.

Vaccines And Autism: Is There A Link?, Irit Hadi

The Science Journal of the Lander College of Arts and Sciences

There has been a worldwide increase in autism cases in the past few decades, but the cause of it is unclear. It has been suggested that vaccines may be contributing to the rise in autism rates. One claim is that the MMR vaccine can cause intestinal inflammation that may lead non-permeable peptides to be transferred to the brain where it will affect neurodevelopment. This may lead to autism with symptoms of developmental regression and gastrointestinal problems. Another major hypothesis that has received much attention is that a mercury-containing compound, thimerosal, found in many vaccines, can have toxic effects on the …

Biofilm Growth Kinetics And Nutrient (N/P) Adsorption In An Urban Lake Using Reclaimed Water: A Quantitative Baseline For Ecological Health Assessment, Tianzhi Wang, Zhenci Wu, Yunkai Li, Mingchao Liang, Zhenhua Wang, Paul Hynds

Articles

Reclaimed wastewater reuse represents an effective method for partial resolution of increasing urban water shortages; however, reclaimed water may be characterized by significant contaminant loading, potentially affecting receiving ecosystem (and potentially human) health. The current study examined biofilm growth and nutrient adsorption in Olympic Lake (Beijing), the largest artificial urban lake in the world supplied exclusively by reclaimed wastewater. Findings indicate that solid particulate, extracellular polymeric substance (EPS) and metal oxide (Al, Fe, Mn) constituent masses adhere to a bacterial growth curve during biofilm formation and growth. Peak values were observed after ≈30 days, arrived at dynamic stability after ≈50days …

Infectious Mononucleosis, Other Infections And Prostate-Specific Antigen Concentration As A Marker Of Prostate Involvement During Infection, Siobhan Sutcliffe, Remington L. Nevin, Ratna Pakpahan, Debra J. Elliott, Marvin E. Langston, Angelo M. De Marzo, Charlotte A. Gaydos, William B. Isaacs, William G. Nelson, Lori J. Sokoll, Patrick C. Walsh, Johnathan M. Zenilman, Steven B. Cersovsky, Elizabeth A. Platz

Chronic Disease Prevention Faculty Publications

No abstract provided.

Uab Magazine - Fall 2016, University Of Alabama At Birmingham

UAB Magazine

No abstract provided.

An Hsus Report: Welfare Issues With The Use Of Hormones And Antibiotics In Animal Agriculture, The Humane Society Of The United States

Agribusiness Collection

No abstract provided.

2016-2017 - College Of Pharmacy Catalog, Office Of The Registrar, East Tennessee State University

Pharmacy Academic Catalogs

No abstract provided.

Using Gatorade® To Control Serum Sodium Levels Of Patients With Hyponatremia, Hannah Elizabeth Degen

Graduate Research Theses & Dissertations

Background: Hyponatremia is a condition in which serum sodium levels are less than 135 mmol/L. It is the most prevalent sodium disorder in hospitalized patients. Currently, the most commonly used treatment for the condition include fluid restriction, carefully monitored hypertonic IV solution and diuretic therapy. In athletes with hyponatremia, low serum sodium levels have been corrected with the administration of an isotonic beverage. Therefore, giving Gatorade® to patients with hyponatremia may be an alternative treatment method to increase serum sodium levels. Objective: The purpose of the study was to examine the effect of oral Gatorade® protocol on serum sodium levels …

University Of Texas At Tyler Course Catalog, 2016 - 2017, University Of Texas At Tyler

Catalogs

No abstract provided.

Effectiveness Of Physical Therapy In An Elderly Man With Lyme Disease: A Case Report, Brittany Johnson

Physical Therapy Scholarly Projects

Background and Purpose. Lyme disease is the most prevalent tick-borne infectious disease in the United States and presents with symptoms that can be treated with physical therapy intervention. The purposes of this case report are to present (1) an example of physical therapy intervention as treatment for a 61 year old male diagnosed with late stage Lyme disease with multiple impairments; (2) to report the patient's functional outcomes; and (3) to provide basis for further research on the effects of physical therapy intervention as it relates to late stage Lyme disease.

Case Description. The 60 year old, male …

The Effectiveness Of Antibiotic Treatment In Lyme Neuroborreliosis, Lane Lindeman

Physician Assistant Scholarly Project Posters

• Lyme disease is caused by human infection with Borrelia burgdorferi, a spirochete transmitted by the Ixodes tick which is indigenous primarily to an increasingly large area of the Northeast and Midwest United States.

• Manifestations of Lyme disease vary greatly, and can result in significant neurologic symptoms associated with complications of neuroborreliosis or neurologic Lyme disease.

• Diagnosis and treatment of Lyme disease and its complications has been a source of debate and confusion for providers and patients alike.

• The purpose of this study was to investigate the effectiveness and efficacy of antibiotic therapy in patients with symptoms …

Cultivate Spring/Summer 2016, Utah State University

Cultivate Magazine

No abstract provided.