Digital Commons Network^™

Customized Medicine And The Limits Of Federal Regulatory Power, Anna B. Laakmann

Vanderbilt Journal of Entertainment & Technology Law

The Food and Drug Administration (FDA) plays a dominant role in setting national policy and standards for the biomedical industry. Yet there are significant statutory constraints on the agency's power. The FDA's main implementing statute, the Federal Food, Drug, and Cosmetic Act (FDCA), bounds the scope of the FDA's regulatory authority. The FDCA cabins FDA power in two important ways: (1) with a few notable exceptions, the FDA lacks power to regulate local activities that are not directly connected to interstate commerce, and (2) the agency may regulate product manufacturers, but not service providers. The FDA has long grappled with …

Mathematical Modeling Of Heart Rate Deflection Point In Relation To Respiratory Compensation And Treadmill Running Performance, Kayla Baker

Electronic Theses and Dissertations

Heart rate deflection point (HRDP), identified as the second breakpoint in the "intensity / heart rate" relationship, is indicative of the anaerobic threshold (AT). This point can be determined via bi-segmental linear regression (2SEG) or through use of the maximal distance model (D-max); however, the relationship between these methods has yet to be investigated 2. Purpose: To compare the use of 2SEG and D-max methods to determine HRDP and to examine the relationship between these values with a metabolic threshold, respiratory compensation point (RCP), as well as running performance [5,000 meter treadmill time trial (5Ktime)]. Methods: Nineteen recreationally active men …

Extracurricular Activities And Substance Use Among Adolescents: A Test Of Social Control And Social Learning Theory, Lynnette Coto

Electronic Theses and Dissertations

The current research examines correlates of adolescent substance use with a focus on extracurricular activities. Given that marijuana is the most widely used illicit drug, and binge drinking can have an early onset the examinations of these two substances were important. Many studies have researched the correlation between substance use and sports, but have not included other extracurricular activities such as academic and fine art clubs. The current research fills this gap in the literature by using the National Longitudinal Study of Adolescent Health (Add Health) and by testing Hirschi's (1969) Social Control Theory and Aker's (1985) Social Learning Theory. …

Anger Maintenance And The Impact Of Shame, Attachment, And Experiential Avoidance, Ahva R. Mozafari

EWU Masters Thesis Collection

Prior to the present study, the relationships between attachment, shame, experiential avoidance, and anger had not been empirically evaluated. This study investigated the influence of shame and attachment style on anger and experiential avoidance. Additionally, this study also explored the differences between those with anxious and avoidant attachment styles and their experiences of anger, as well as their ability to confront emotions. It was hypothesized that the combination of attachment, shame, and experiential avoidance would be predictors of anger. Finally, it was hypothesized that shame experiences would mediate the relationships between attachment and anger as well as attachment and experiential …

Gender Nonconformity, Psychosocial Stressors, And Psychopathology: Looking Beyond Sexual Orientation, Kathryn M. Oost

Graduate Student Theses, Dissertations, & Professional Papers

LGBT individuals experience disproportionately more victimization than their heterosexual and cisgender counterparts. Within these populations, perceived gender nonconformity predicts even higher rates of victimization. The current investigation examined relationships between gender nonconformity, experiences with victimization, and psychopathology among 671 students from the University of Montana, including 64 LGBT-identified individuals, who took part in an online study as part of course requirements. Hierarchical regressions were calculated to examine the relationships between gender expression, victimization, and psychopathology while controlling for sexual orientation, gender identity, and ethnicity. Gender nonconformity was a significant predictor of reported victimization, beyond sexual orientation and ethnicity (ΔR …

Issues Of Ethics Training In Turkish Counselor Education As Associated With Accreditation, Certification, And Licensure, Umut Arslan

Graduate Student Theses, Dissertations, & Professional Papers

The purpose of this study was to investigate qualifications of ethics training in counselor education programs in Turkey associated with accreditation, certification, and licensure. The survey data were collected from 251 Turkish counseling students to examine differences in ethical judgments between freshmen and seniors. This survey was based on the counselor ethical practice and belief survey by Gibson and Pope (1993) regarding Turkish counseling ethical codes and sources of ethics information. I used chi-square analyses to analyze the Turkish data. Statistically significant differences were found between university seniors and freshmen in items that related to dual relationships, multicultural counseling, competency, …

The Effects Of Aging On Multiple Postural Muscle Control And Postural Sway Behavior, Adriana Menezes Degani

Graduate Student Theses, Dissertations, & Professional Papers

Episodes of instability and falls in the elderly represent a major public health concern. The lack of scientific information about the effects of age-related changes on neurophysiological mechanisms of postural control has limited the advance in the field of fall prevention and rehabilitation of balance disorders. The overall goal of this dissertation was to investigate the effects of aging on postural control. Considering the progressive non-homogeneous deterioration of aging physiological systems, a series of five experimental studies, with healthy young and healthy nonfaller older adults performing upright stance tasks, explored three main hypotheses: (1) intermuscular coherence analysis is able to …

Consumer Financial Education And Financial Capability, Jing Jian Xiao, Barbara O'Neill

Human Development and Family Science Faculty Publications

The purpose of this study was to explore potential effects of financial education on the financial capability of American consumers. Data from the 2012 National Financial Capability Study were used to test the hypothesis that financial education is positively associated with financial capability. Four financial literacy and behaviour variables were used to form a financial capability index. Multivariate linear regression results showed that, after controlling for demographic and financial variables, respondents who ever received financial education had higher scores in all financial capability indicators (objective financial literacy, subjective financial literacy, desirable financial behaviour, perceived financial capability and the financial capability …

The Young And The Restless: Socializing Trumps Sleep, Fear Of Missing Out, And Technological Distractions In First-Year College Students, Sue K. Adams, Desirée N. Williford, Annemarie Vaccaro, Tiffani S. Kisler, Alyssa Francis, Barbara M. Newman

Human Development and Family Science Faculty Publications

College students are a sleep-deprived population, with first-year students facing a number of specific challenges to sleep. As students transition into and through the first year of college, sleep may be sacrificed for a variety of reasons. Semi-structured interviews were conducted with fifteen first-year students, exploring factors that impacted sleep during the first semester of college. Study participants identified three unique but related themes that impacted their sleep: socializing trumps sleep; fear of missing out; and social/technological distractions. Implications are provided for balancing social, academic and biological demands in emerging adulthood.

Outcome Measures For Mild Balance And Cognitive Decline In A Pre-Old Adult: A Case Report, Melissa Chan, Shari Rone-Adams

Internet Journal of Allied Health Sciences and Practice

Background and Purpose. Early detection and treatment of age-related decline, particularly balance and cognition, are increasingly being emphasized in current research. However, the majority of research on older adults focuses on participants who are 65 years and older. For individuals who are 60-64 years old, this is an age range where they may or may not be considered an older adult. This poses a problem applying the results of these studies to pre-old adults to accurately diagnose, measure and classify risk in the areas of cognition and balance. Case Description. The patient is a 61-year-old woman with a clinical diagnosis …

Craig S. Keener, Miracles: The Credibility Of The New Testament Account, Volumes 1 And 2, Johannes Grössl

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Book Review: The Quest For Consitutionalism: South Africa Since 1994, Penelope Andrews

Other Publications

No abstract provided.

The Quest For Constitutionalism: South Africa Since 1994, Penelope Andrews

Other Publications

No abstract provided.

Briefing Book: Tort Litigation By The Numbers. Center For Justice And Democracy, Joanne Doroshow, Emily Gottlieb

Other Publications

The Center for Justice & Democracy at New York Law School released its new briefing book, TORT LITIGATION: BY THE NUMBERS. The book highlights the latest information and statistics on tort (personal injury) suits across the country, based largely on recent statistics from the National Center for State Courts (NCSC),[1] the U.S. Department of Justice and other research institutions. Principal authors of the briefing book are Emily Gottlieb, CJ&D’s Deputy Director for Law and Policy, and Joanne Doroshow, CJ&D Executive Director. Said Doroshow, “This briefing book shows that injured Americans hardly ever sue wrongdoers for their injuries, and when they …

Eeoc Win Shows What Trump Era Might Undo, Arthur S. Leonard

Other Publications

No abstract provided.

Who Owns Gene Editing? Patents In The Time Of Crispr, Jacob S. Sherkow

Other Publications

New gene-editing technologies, like CRISPR, promise revolutionary advances in biology and medicine. However, several patent disputes in the USA and UK may have complicated who can use CRISPR. What does this mean for the future of gene editing?

Conviction Nixed, But No Wrongful Imprisonment Suit For Poz Man, Arthur S. Leonard

Other Publications

No abstract provided.

Current Issues In Therapeutic Jurisprudence, David Wexler

Articles & Chapters

No abstract provided.

Variant Discovery And Fine Mapping Of Genetic Loci Associated With Blood Pressure Traits In Hispanics And African Americans., Nora Franceschini, Cara L. Carty, Yingchang Lu, Ran Tao, Yun Ju Sung, Ani Manichaikul, +20 Additional Authors

Clinical Research and Leadership Faculty Publications

Despite the substantial burden of hypertension in US minority populations, few genetic studies of blood pressure have been conducted in Hispanics and African Americans, and it is unclear whether many of the established loci identified in European-descent populations contribute to blood pressure variation in non-European descent populations. Using the Metabochip array, we sought to characterize the genetic architecture of previously identified blood pressure loci, and identify novel cardiometabolic variants related to systolic and diastolic blood pressure in a multi-ethnic US population including Hispanics (n = 19,706) and African Americans (n = 18,744). Several known blood pressure loci replicated in African …

Identification And Use Of Frailty Indicators From Text To Examine Associations With Clinical Outcomes Among Patients With Heart Failure., Yijun Shao, April F Mohanty, Ali Ahmed, Charlene R Weir, Bruce E Bray, Rashmee U Shah, Douglas Redd, Qing Zeng-Treitler

Clinical Research and Leadership Faculty Publications

Frailty is an important health outcomes indicator and valuable for guiding healthcare decisions in older adults, but is rarely collected in a quantitative, systematic fashion in routine healthcare. Using a cohort of 12,000 Veterans with heart failure, we investigated the feasibility of topic modeling to identify frailty topics in clinical notes. Topics were generated through unsupervised learning and then manually reviewed by an expert. A total of 53 frailty topics were identified from 100,000 notes. We further examined associations of frailty with age-, sex-, and Charlson Comorbidity Index-adjusted 1-year hospitalizations and mortality (composite outcome) using logistic regression. Frailty (≤ 4 …

Cultural Influences On The Weight, Diet, And Physical Activity Of Pregnant Immigrant Latinas, Martha Eugenia Dominguez

Walden Dissertations and Doctoral Studies

The problem addressed in this phenomenological study is how culture and acculturation can potentially influence gestational weight during pregnancy, leading to overweight and obesity among immigrant Latinas. To understand the possible influence of culture and acculturation on the diet, exercise, and weight of pregnant immigrant Latinas, the experiences of immigrant Latinas who had undergone a pregnancy in Mexico and were pregnant in California were examined. The ecological model theory was applied as a framework for exploring the participants' experiences regarding nutrition, physical activity, and weight gain. Semistructured interviews with 10 qualified participants were conducted. Data analysis entailed an inductive approach …

U. S. Nursing Students' Perceptions Of Safe Medication Administration, Kathy F. Johnson

Walden Dissertations and Doctoral Studies

Medication errors are a global concern that may affect patients' hospital stays, patients' lives after discharge, treatment costs, and mortality rates. Understanding medication errors among nursing students may help in preventing these errors as nurses are responsible for safe medication administration. The purpose of this descriptive phenomenological study was to examine upper-level nursing students' understanding of and experiences with medication administration and patient safety. Benner's nursing theory of novice to expert and Dreyfus's model of skill acquisition comprised the conceptual framework. Research questions focused on students' perceptions of safe medication administration. Face-to-face interviews were conducted with 7 upper-level nursing students …

An Evidence-Based Educational Intervention To Improve Nursing Staff's Critical Thinking And Decision-Making Skills, Rene Norene Barron-Kagan

Walden Dissertations and Doctoral Studies

An Evidence-Based Educational Intervention to Improve Nursing Staff's Critical Thinking and Decision-Making Skills

by

Rene N. Kagan

MSN, University of New Mexico, 2009

BS, University of Phoenix, 2000

Project Submitted in Partial Fulfillment

of the Requirements for the Degree of

Doctor of Nursing Practice

Walden University

September 2016

Hospitalized patients in acute care settings are at a high risk of developing health complications that can eventually lead to failure to rescue (FTR) situations. The aim of this project was to deliver a structured comprehensive medical-surgical competency plan for acute care nurses to detect deterioration in a patient's condition through the …

Implementation Procedures For Puerto Rico's Environmental Laws, Sara Enid Camerón

Walden Dissertations and Doctoral Studies

In 2004, Puerto Rico's new environmental legislation became part of the penal code with the intention of protecting the island nation's natural resources through criminal prosecution. However, the problem is a dearth of information about the prosecutions of environmental crimes and the law enforcement agent's implementation practices. The purpose of this study was to describe the execution of the law and the few cases prosecuted. Lipsky and Hull and Hjern's theory of implementation were used to help answer the research question: What are the implementation procedures of law enforcement agents on Puerto Rico's environmental crimes law, and what can be …

Perceptions Of Emergency Preparedness Among Immigrant Hispanics Living In Oklahoma City, Oklahoma, Rebekah Doyle

Walden Dissertations and Doctoral Studies

Tornadoes are occurring with increased frequency in Oklahoma. Emergency preparedness planning is essential to decreasing individuals' risks of injury or death from a tornado. Research on immigrant Hispanics' knowledge and perceptions of emergency preparedness is limited. The purpose of this study was to explore the perceptions and lived experiences of immigrant Hispanics who had experienced a tornado or other crisis weather conditions in Oklahoma during spring of 2013. The research questions explored their perceived risk for injury and knowledge of tornado preparedness planning. The health belief model provided the theoretical underpinnings for this qualitative phenomenological study. Semi structured interviews were …

Student Perceptions Of Factors Affecting Retention In A Rural Associate Degree Nursing Program, Jodi Garcia

Walden Dissertations and Doctoral Studies

High nursing student attrition rates at a community college in a southwestern state were noted as a significant problem by nursing faculty and college administration because of a nursing shortage and subsequent health care issues in the surrounding community. The purpose of this project study was to explore the perceptions of nursing graduates regarding the influences that led to or impeded their success in completion of the associate degree nursing program. Additionally, perspectives of the usefulness of remediation sessions provided for students failing a course were investigated. This qualitative case study, guided by transformative learning theory, included a sample of …

Beliefs Among Mothers Of Adolescent Females On Cervical Cancer Vaccination, Aja Rochelle Gardner

Walden Dissertations and Doctoral Studies

Hispanic and African American women are infected with sexually transmitted diseases more often than are Caucasian women. This racial disparity is also seen in the incidence of human papillomavirus (HPV) and cervical cancer. The medical connection between HPV and cervical cancer is often unknown or misunderstood among women. This study addressed the beliefs and subsequent health decisions of minority parents regarding whether to get their daughters vaccinated against HPV. The theoretical framework for this study was Rosenstock's health belief model (HBM). The specific study design used was Husserl and Heidegher's theory on Phenomenology. This qualitative study utilized focus groups containing …

Factors Affecting Body Mass Index Levels In African American Women Living In North Carolina, Padmini Shanti Kirpalani

Walden Dissertations and Doctoral Studies

The prevalence of obesity has doubled over the past 25 years in the United States, particularly in North Carolina. Obesity is influenced by biological, social, and environmental factors; its prevalence has been found to be higher among African American women and other racial ethnic minorities. Guided by the social ecological model, the purpose of this cross sectional study was to examine the relationship of the psycho-social, psycho-behavioral factors, and body mass index levels (BMI) in African American women living in North Carolina versus their Hispanic American and European American counterparts. A logistic regression model using secondary data from the Behavioral …

Strategies To Implement Iso 9001 In A Government Organization In Jamaica, Yvette M. Castell

Walden Dissertations and Doctoral Studies

Managers of government organizations in Jamaica often have difficulty implementing the International Organization for Standardization (ISO) 9001 standard. Jamaica's Minister of Industry, Investment, and Commerce considered ISO 9001 certification as critical for international competitiveness as lacking the standard had the potential to become a barrier to trade. The purpose of this single case study was to explore the strategies that managers of a government organization in Jamaica used to implement ISO 9001 successfully. The conceptual framework was the total quality management concept encompassing Deming's plan-do-check-act cycle. Data collection entailed organizational document reviews and semistructured interviews of 4 managers in an …

Perceptions Of Immunizations As Health Prevention Among Female Mexican Immigrants In Oklahoma, Jennifer Doyle

Walden Dissertations and Doctoral Studies

Research on health prevention behaviors of Mexican immigrant mothers regarding immunizations has been limited. As of 2014, Hispanics or Latinos comprised 9.6% of the population of the state of Oklahoma and were the largest minority group within Oklahoma. This minority population has continued to grow at a rapid rate in Oklahoma. The purpose of this study was to explore the perceptions of immunizations held by Mexican immigrants who are mothers residing in Oklahoma. The aim of this study was to identify their perceived risk of contracting a vaccine-preventable disease if not immunized and knowledge of immunizations as a health prevention …