Digital Commons Network^™

Component Greenhouse Gas Fluxes And Radiative Balance From Two Deltaic Marshes In Louisiana: Pairing Chamber Techniques And Eddy Covariance, Ken W. Krauss, Guerry O. Holm Jr., Brian C. Perez, David E. Mcwhorter, Nicole Cormier, Rebecca F. Moss, Darren J. Johnson, Scott C. Neubauer, Richard C. Raynie

United States Geological Survey: Staff Publications

Coastal marshes take up atmospheric CO₂ while emitting CO₂, CH₄, and N₂O. This ability to sequester carbon (C) is much greater for wetlands on a per area basis than from most ecosystems, facilitating scientific, political, and economic interest in their value as greenhouse gas sinks. However, the greenhouse gas balance of Gulf of Mexico wetlands is particularly understudied. We describe the net ecosystem exchange (NEE_c) of CO₂ and CH₄ using eddy covariance (EC) in comparison with fluxes of CO₂, CH₄, and N₂O using …

Interpreting And Predicting The Spread Of Invasive Wild Pigs, Nathan P. Snow, Marta A. Jarzyna, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

1. The eruption of invasive wild pigs (IWPs) Sus scrofa throughout the world exemplifies the need to understand the influences of exotic and nonnative species expansions. In particular, the continental USA is precariously threatened by a rapid expansion of IWPs, and a better understanding of the rate and process of spread can inform strategies that will limit the expansion.

2. We developed a spatially and temporally dynamic model to examine three decades (1982– 2012) of IWP expansion, and predict the spread of IWPs throughout the continental USA, relative to where IWPs previously inhabited. We used the model to predict where …

Urolithin A, C And D, But Not Iso-Urolithin A And Urolithin B, Attenuate Triglyceride Accumulation In Human Cultures Of Adipocytes And Hepatocytes, Inhae Kang, Yongeun Kim, Francisco A. Tomás-Barberán, Juan Carlos Espín, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Scope: Urolithins (Uro) are ellagic acid (EA)-derived metabolites produced by gut microbes. There is a growing interest in the biological activities of Uro. Our aim was to evaluate the impacts of Uro on regulating triglyceride (TG) accumulation using cultures of primary human adipocytes and hepatoma Huh7 cells.

Methods and Results: UroA, B, C, D, and iso-UroA, were used to determine the effect of Uro on adipogenesis and lipogenesis. Individual Uro (30 M) were added to human adipogenic stem cells (hASCs) during differentiation. UroA, C and D, but not iso-UroA and UroB, significantly inhibited new fat cell formation by decreasing TG …

Suppression Of Nlrp3 Inflammasome By Γ-Tocotrienol Ameliorates Type 2 Diabetes, Yongeun Kim, Wei Wang, Meshail Okla, Inhae Kang, Regis Moreau, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

The Nod-like receptor 3 (NLRP3) inflammasome is an intracellular sensor that sets off the innate immune system in response to microbial-derived and endogenous metabolic danger signals. We previously reported that γ-tocotrienol (γT3) attenuated adipose tissue inflammation and insulin resistance in diet-induced obesity, but the underlying mechanism remained elusive. Here, we investigated the effects of γT3 on NLRP3 inflammasome activation and attendant consequences on type 2 diabetes. γT3 repressed inflammasome activation, caspase-1 cleavage, and interleukin (IL) 1β secretion in murine macrophages, implicating the inhibition of NLRP3 inflammasome in the anti-inflammatory and antipyroptotic properties of γT3. Furthermore, supplementation of leptin-receptor KO mice …

Disparities In Access To Preventive Health Care Services Among Insured Children In A Cross Sectional Study, Christian King

Department of Nutrition and Health Sciences: Faculty Publications

Children with insurance have better access to care and health outcomes if their parents also have insurance. However, little is known about whether the type of parental insurance matters. This study attempts to determine whether the type of parental insurance affects the access to health care services of children. I used data from the 2009–2013 Medical Expenditure Panel Survey and estimated multivariate logistic regressions (N=26,152). I estimated how family insurance coverage affects the probability that children have a usual source of care, well-child visits in the past year, unmet medical and prescription needs, less than 1 dental visit per year, …

Four Weeks Of High- Versus Low-Load Resistance Training To Failure On The Rate Of Torque Development, Electromechanical Delay, And Contractile Twitch Properties, N.D.M. Jenkins, Terry J. Housh, S.L. Buckner, H.C. Bergstrom, C. M. Smith, Kristen C. Cochrane, E.C. Hill, Amelia A. Miramonti, Richard J. Schmidt, G. O. Johnson, Joel T. Cramer

Department of Nutrition and Health Sciences: Faculty Publications

The purpose of this study was to investigate the effects of 4-weeks of high- versus low-load resistance training to failure on rate of torque development (RTD), electromechanical delay (EMD), and contractile twitch characteristics. Fifteen men (mean±SD; age=21.7±2.4 yrs) were randomly assigned to either a high- (80% 1RM; n=7) or low-load (30% 1RM; n=8) training group and completed elbow flexion resistance training to failure 3 times per week for 4 weeks. The participants were tested at baseline, 2-, and 4-weeks of training. Peak RTD (pRTDV) and RTD at 0-30 (RTD30V), 0-50 (RTD50V), 0-100 (RTD100V), and 0-200 (RTD200V) ms, integrated EMG amplitude …

Soft Drinks Consumption And Child Behaviour Problems: The Role Of Food Insecurity And Sleep Patterns, Christian King

Department of Nutrition and Health Sciences: Faculty Publications

Objective: To examine whether the association between soft drinks consumption and child behaviour problems differs by food security status and sleep patterns in young children.

Design: Cross-sectional observational data from the Fragile Families and Child Wellbeing Study (FFCWS), which collected information on food insecurity, soft drinks consumption, sleep patterns and child behaviour problems. Bivariate and multivariate ordinary least-squares regression analyses predicting child behaviour problems and accounting for socio-economic factors and household characteristics were performed.

Setting: Twenty urban cities in the USA with a population of 200 000 or more.

Subjects: Parental interviews of 2829 children who were about 5 years …

Effect Of Sex On Torque, Recovery, Emg, And Mmg Responses To Fatigue, E.C. Hill, Terry J. Housh, C. M. Smith, Kristen C. Cochrane, N.D.M. Jenkins, Joel T. Cramer, Richard J. Schmidt, G. O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

The purpose of the present investigation was to examine the effect of sex on maximal voluntary isometric contraction (MVIC) torque and the EMG and MMG responses as a result of fatiguing, intermittent, submaximal (65% of MVIC), isometric elbow flexion muscle contractions. Methods: Eighteen men and women performed MVIC trials before (pretest), after (posttest), and 5-min after (5-min recovery) performing 50 intermittent, submaximal isometric muscle contractions. Surface electromyographic (EMG) and mechanomyographic (MMG) signals were simultaneously recorded from the biceps brachii muscle. Results: As a result of the fatiguing workbout torque decreased similarly from pretest to posttest for both the men (24.0%) …

Effects Of Fatiguing Constant Versus Alternating Intensity Intermittent Isometric Muscle Actions On Maximal Torque And Neuromuscular Responses, C. M. Smith, Terry J. Housh, E.C. Hill, Kristen C. Cochrane, N.D.M. Jenkins, Richard J. Schmidt, G. O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Objective: To determine the effects of constant versus alternating applications of torque during fatiguing, intermittent isometric muscle actions of the leg extensors on maximal voluntary isometric contraction (MVIC) torque and neuromuscular responses. Methods: Sixteen subjects performed two protocols, each consisting of 50 intermittent isometric muscle actions of the leg extensors with equal average load at a constant 60% MVIC or alternating 40 then 80% (40/80%) MVIC with a work-to-rest ratio of 6-s on and 2-s off. MVIC torque as well as electromyographic signals from the vastus lateralis (VL), vastus medialis (VM), and rectus femoris (RF) and mechanomyographic signals from the …

Combined Iron Deficiency And Low Aerobic Fitness Doubly Burden Academic Performance Among Women Attending University, Samuel P. Scott, Mary Jane Desouza, Karsten Koehler, Laura E. Murray-Kolb

Department of Nutrition and Health Sciences: Faculty Publications

Background: Academic success is a key determinant of future prospects for students. Cognitive functioning has been related to nutritional and physical factors. Here, we focus on iron status and aerobic fitness in young-adult female students given the high rate of iron deficiency and declines in fitness reported in this population. Objectives: We sought to explore the combined effects of iron status and fitness on academic success and to determine whether these associations are mediated by cognitive performance.

Methods: Women (n = 105) aged 18–35 y were recruited for this cross-sectional study. Data were obtained for iron biomarkers, peak oxygen …

Low Energy Availability In Exercising Men Is Associated With Reduced Leptin And Insulin But Not With Changes In Other Metabolic Hormones, Karsten Koehler, Neele R. Hoerner, Jenna C. Gibbs, Christoph Zinner, Hans Braun, Mary Jane De Souza, Wilhelm Schaenzer

Department of Nutrition and Health Sciences: Faculty Publications

Low energy availability, defined as low caloric intake relative to exercise energy expenditure, has been linked to endocrine alterations frequently observed in chronically energy-deficient exercising women. Our goal was to determine the endocrine effects of low energy availability in exercising men. Six exercising men (V_O2peak : 49.3 ± 2.4 ml · kg⁻¹ · min⁻¹) underwent two conditions of low energy availability (15 kcal · kg⁻¹ fat-free mass [FFM] · day⁻¹) and two energy-balanced conditions (40 kcal · kg⁻¹ FFM · day⁻¹) in randomized order. During one low energy availability and …

A Qualitative Phenomenological Exploration Of Teachers’ Experience With Nutrition Education, Elisha M. Hall, Weiwen Chai, Julie A. Albrecht

Department of Nutrition and Health Sciences: Faculty Publications

Background:

Nutrition education delivered by classroom teachers has become a popular intervention designed to combat childhood obesity. However, few qualitative studies have explored nutrition education with teachers.

Purpose:

The purpose of this study was to explore how elementary teachers describe their experience with nutrition education.

Methods:

A qualitative phenomenological approach was used. Semistructured interviews, observations, and document analysis were conducted with 10 teachers who delivered nutrition education in their classrooms. Inductive coding was used to determine invariant constituents, reduce constituents to categories, and cluster categories into themes. Reliability and validity were accomplished through intercoder agreement, audio recording, triangulation, bracketing, and …

Cranberries And Cancer: An Update Of Preclinical Studies Evaluating The Cancer Inhibitory Potential Of Cranberry And Cranberry Derived Constituents, Katherine M. Weh, Jennifer L. Clarke, Laura A. Kresty

Department of Nutrition and Health Sciences: Faculty Publications

Cranberries are rich in bioactive constituents reported to influence a variety of health benefits, ranging from improved immune function and decreased infections to reduced cardiovascular disease and more recently cancer inhibition. A review of cranberry research targeting cancer revealed positive effects of cranberries or cranberry derived constituents against 17 different cancers utilizing a variety of in vitro techniques, whereas in vivo studies supported the inhibitory action of cranberries toward cancers of the esophagus, stomach, colon, bladder, prostate, glioblastoma and lymphoma. Mechanisms of cranberry-linked cancer inhibition include cellular death induction via apoptosis, necrosis and autophagy; reduction of cellular proliferation; alterations in …

Association Of Individual And Community Factors With C-Reactive Protein And 25-Hydroxyvitamin D: Evidence From The National Health And Nutrition Examination Survey (Nhanes), Weiwen Chai, Jessie X. Fan, Ming Wen

Department of Nutrition and Health Sciences: Faculty Publications

Many individual and community/neighborhood factors may contribute to inflammation and vitamin D deficiency leading to the development of chronic diseases. This study examined the associations of serum Creactive protein (CRP) and 25-hydroxyvitamin D [25(OH)D] levels with individual and community/neighborhood (tract-level or county-level) factors using a nationally representative sample from 2001–2006 National Health and Nutrition Examination Survey (NHANES). Data from the 2001–2006 waves of the continuous NHANES was merged with the 2000 census and other neighborhood data sources constructed using geographic information system. Associations between multilevel factors and biomarker levels were assessed using multilevel random-intercept regression models. 6643 participants aged 19–65 …

Impacts Of High-Protein Oral Nutritional Supplements Among Malnourished Men And Women With Sarcopenia: A Multicenter, Randomized, Double-Blinded, Controlled Trial, Joel T. Cramer, Alfonso J. Cruz-Jentoft, Francesco Landi, Mary Hickson, Mauro Zamboni, Suzette L. Pereira, Deborah S. Hustead, Vikkie A. Mustad

Department of Nutrition and Health Sciences: Faculty Publications

Background: Recent evidence suggests that nutritional interventions may improve muscle outcomes in malnutrition and sarcopenia. Objectives: We evaluated the effects of 2 high-quality oral nutritional supplements (ONS) differing in amount and type of key nutrients in older adult men and women. Design: A multicenter, randomized, double-blinded, controlled clinical trial. Participants: Malnourished and sarcopenic men and women, 65 years and older (n ¼ 330). Intervention: A 24-week intervention period with 2 energy-rich (330 kcal) ONS treatment groups: Control ONS (C_ONS,14 g protein; 147 IU vitamin D₃) versus Experimental ONS (E_ONS, 20 g protein; 499 IU …

Muscle- And Mode-Specific Responses Of The Forearm Flexors To Fatiguing, Concentric Muscle Actions, Ethan C. Hill, Terry J. Housh, Cory M. Smith, Richard Schmidt, Glen O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Background: Electromyographic (EMG) and mechanomyographic (MMG) studies of fatigue have generally utilized maximal isometric or dynamic muscle actions, but sport- and work-related activities involve predominately submaximal movements. Therefore, the purpose of the present investigation was to examine the torque, EMG, and MMG responses as a result of submaximal, concentric, isokinetic, forearm flexion muscle actions. Methods: Twelve men performed concentric peak torque (PT) and isometric PT trials before (pretest) and after (posttest) performing 50 submaximal (65% of concentric PT), concentric, isokinetic (60°·s^-1), forearm flexion muscle actions. Surface EMG and MMG signals were simultaneously recorded from the biceps brachii and …

Relationship Between Concentrations Of Lutein And Stard3 Among Pediatric And Geriatric Human Brain Tissue, Jirayu Tanprasertsuk, Binxing Li, Paul S. Bernstein, Rohini Vishwanathan, Mary Ann Johnson, Leonard Poon, Elizabeth J. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Lutein, a dietary carotenoid, selectively accumulates in human retina and brain. While many epidemiological studies show evidence of a relationship between lutein status and cognitive health, lutein’s selective uptake in human brain tissue and its potential function in early neural development and cognitive health have been poorly evaluated at a molecular level. The objective of this study was to evaluate the cross-sectional relationship between concentrations of brain lutein and StARD3 (identified as its binding protein in retinal tissue) among three age groups: infants (1–4 months, n = 10), older adults (55–86 years, n = 8), and centenarians (98–105 years, n …

Pharmacological And Genetic Modulation Of Rev-Erb Activity And Expression Affects Orexigenic Gene Expression, Ariadna Amador, Yongjun Wang, Subhashis Banerjee, Theodore M. Kameneka, Laura A. Solt, Thomas P. Burris

Department of Nutrition and Health Sciences: Faculty Publications

The nuclear receptors REV-ERBα and REV-ERBβ are transcription factors that play pivotal roles in the regulation of the circadian rhythm and various metabolic processes. The circadian rhythm is an endogenous mechanism, which generates entrainable biological changes that follow a 24-hour period. It regulates a number of physiological processes, including sleep/wakeful cycles and feeding behaviors. We recently demonstrated that REV-ERB-specific small molecules affect sleep and anxiety. The orexinergic system also plays a significant role in mammalian physiology and behavior, including the regulation of sleep and food intake. Importantly, orexin genes are expressed in a circadian manner. Given these overlaps in function …

Modifying M-44s To Reduce Risk Of Activation By Swift Fox, Julie K. Young

United States Department of Agriculture Wildlife Services: Staff Publications

M-44s are spring-powered sodium cyanide ejectors commonly used in the United States to manage livestock depredation by coyotes (Canis latrans). While highly selective for canids, improvements could reduce risk to nontarget canids, especially State-Endangered or -Threatened canids such as the swift fox (Vulpes velox). In 2012–2013, we tested M-44s set at modified heights to determine whether height modifications reduced risk to swift foxes without reducing activation rates by coyotes. We presented captive coyotes housed at the USDA National Wildlife Research Center’s Predator Research Facility, Millville, Utah, USA, with M-44s at various test heights to determine a …

The Migratory Bird And Habitat Research Laboratory And The Accelerated Research Program, Richard A. Coon

United States Geological Survey: Staff Publications

The Patuxent Wildlife Research Center (Patuxent) housed two important programs that were not supervised through the office of the Director of Patuxent during the 1960s and 1970s. Although they received administrative support from Patuxent, they were supervised from the U.S. Fish and Wildlife Service (USFWS) headquarters in Washington, D.C. One, the Migratory Bird Populations Station (MBPS), was established in 1961; the other, the Migratory Bird and Habitat Research Laboratory (MBHRL), was established in 1972 (Perry, 2004). This chapter briefly discusses MBPS and how some of its functions were transferred to MBHRL when this new laboratory was created.

Limited Antigenic Diversity In Contemporary H7 Avian-Origin Influenza A Viruses From North America, Yifei Xu, Elizabeth Bailey, Erica Spackman, Tao Li, Hui Wang, Li-Ping Long, John A. Baroch, Fred L. Cunningham, Xiaoxu Lin, Richard G. Jarman, Thomas J. Deliberto, Xiu-Feng Wan

United States Department of Agriculture Wildlife Services: Staff Publications

Subtype H7 avian–origin influenza A viruses (AIVs) have caused at least 500 confirmed human infections since 2003 and culling of >75 million birds in recent years. Here we antigenically and genetically characterized 93 AIV isolates from North America (85 from migratory waterfowl [1976–2010], 7 from domestic poultry [1971–2012], and 1 from a seal [1980]). The hemagglutinin gene of these H7 viruses are separated from those from Eurasia. Gradual accumulation of nucleotide and amino acid substitutions was observed in the hemagglutinin of H7 AIVs from waterfowl and domestic poultry. Genotype characterization suggested that H7 AIVs in wild birds form diverse and …

Transcriptional Profiling Of Ileocecal Valve Of Holstein Dairy Cows Infected With Mycobacterium Avium Subsp. Paratuberculosis, Randy J. Hempel, J. P. Bannantine, Judith R. Stabel

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Johne’s disease is a chronic infection of the small intestine caused by Mycobacterium avium subspecies paratuberculosis (MAP), an intracellular bacterium. The events of pathogen survival within the host cell(s), chronic inflammation and the progression from asymptomatic subclinical stage to an advanced clinical stage of infection, are poorly understood. This study examines gene expression in the ileocecal valve (ICV) of Holstein dairy cows at different stages of MAP infection. The ICV is known to be a primary site of MAP colonization and pro-vides an ideal location to identify genes that are relevant to the progression of this disease. RNA was prepared …

Differential Response: Misrepresentation Of Cps Investigation And Case Fact Finding, Frank E. Vandervort, Ronald C. Hughes

Articles

Traditionally, a host of necessary case fact-finding responsibilities and activities has been used by public Child Protective Services (CPS) agencies to ensure that they can achieve mandates to protect children from maltreatment as well as to strengthen and preserve the families of atrisk children. The primary CPS case fact-finding activities include risk assessment, investigation (both CPS and forensic), and family assessment. Information collected while engaged in any one of these three activities will often be relevant and important to the others. However, each case fact-finding activity also requires specific inquiry to elicit information that is essential to achieve its distinct …

The Worst Place In The World To Be A Woman?: Women's Conflict Experiences In The Democratic Republic Of The Congo, Megan Bailey 16

Honor Scholar Theses

No abstract provided.

Age-Related Hearing Loss: Inhibition--Excitation Balance In The Rat Inferior Colliculus, Sydney Cason 16

Honor Scholar Theses

Aging is an increasingly important research topic due to the aging populations in the United States and other developed countries. One aspect of aging, age-related hearing loss, is caused by changes in the peripheral and the central auditory systems. The age-related changes in the central auditory system, including the integrating midbrain area inferior colliculus (IC), are not well understood. Studies have revealed that GABA levels in the IC decrease with age. However, no studies have quantified the age-related changes in IC glutamate levels or the relationship between GABA and glutamate levels in the aging IC. This study aimed to elucidate …

The Method Of Madness: A Brief Biography Of Schizophrenia, Riley Hawkins 16

Honor Scholar Theses

No abstract provided.

Joining Forces:Establishing A Cardio-Oncology Program, Caroline Austin-Mattison

Yale School of Nursing Digital Theses

Abstract

Patients have been surviving cancer diagnoses at a steady increasing rate over the past few decades. In spite of the encouraging decline in cancer morbidity, the cardiovascular effect of some chemotherapy medications is concerning. Moreover, even though there is extensive knowledge in regards to the pathophysiology and increased risk of cardiotoxicity, there is a lack of specific guidelines and adequate cardio-oncology programs focused on reducing cardiovascular risks or disease in patients undergoing cancer treatment. The high incidence of both cardiovascular disease (CVD) and cancer warrants the collaboration of oncology and cardiology providers to screen, treat promptly, and thereby provide …

Community Pressure Ulcer Occurrence: Description On Hospital Admission, Lisa Quay Corbett

Yale School of Nursing Digital Theses

Abstract

Purpose: To describe community-dwelling adults admitted to acute care with a present-on-admission (POA) pressure ulcer (PU). Specific aims: 1) Measure 1-year POA-PU prevalence, 2) Determine pre-hospital location of patients with POA-PU, 3) Describe demographics, PU characteristics, risk factors, and post-hospital outcome of community-dwelling adults admitted to hospital with a PU.

Design: Retrospective descriptive study.

Subjects and Setting: The sample included all adults, over age 18, admitted to an 800-bed urban academic medical center in New England over a 1-year period with a POA-PU.

Methods: Subjects were identified from a clinically validated PU registry. Data were extracted electronically from selected …

Design Of An Evidence-Based Mentorship Program For Inpatient Nurse Practitioners, Kimberley Shamara Ennis

Yale School of Nursing Digital Theses

Abstract

Purpose: To examine the literature on mentorship from nursing and other professional disciplines in order to identify and validate key components to guide the development and implementation of a formal mentorship program for nurse practitioners (NPs) practicing in the inpatient setting.

Methods: A comprehensive review of the literature on mentorship was conducted using Cumulative Index to Nursing and Allied Health Literature (CINAHL), PUBMED, OVID, MEDLINE, EMBASE, and Google Scholar. Evidence based material was identified, extracted, and validated by a panel of five experts to determine key components for program development and implementation.

Conclusions: From the evidence reviewed, the components …

A Survey Of Heathcare Simulation In The State Of Oklahoma, Danyel Louise Germain

Yale School of Nursing Digital Theses

Introduction: Simulation is a critical tool that enables healthcare agencies and educational institutions to meet local, state, and national workforce education needs. In order to understand the current use of simulation and available resources at health professions schools in the state of Oklahoma, a comprehensive statewide assessment of simulation resources was conducted.

Methods: Administrators, faculty, and staff at health professions schools participated in an online statewide survey, replicated from the Florida Center for Nursing 2010 Nursing Simulation Resources in Florida survey.

Results: The overall survey response rate was 45.6%. Findings indicate that simulation is used to enhance the educational experiences …