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2016

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Gwu Alumna’S Quest For Olympics Began With Class Project, Office Of University Communications Nov 2016

Gwu Alumna’S Quest For Olympics Began With Class Project, Office Of University Communications

Gardner-Webb NewsCenter Archive

As an undergraduate and graduate student at Gardner-Webb University, Kristen Hurley (’14) — a new member of the U.S. National Bobsled Team — thrived on accepting academic and athletic challenges. Her determination paid off on the track and field team, where she was a seven-time all-conference performer, and in a class taught by Dr. Ken Baker, chair of the GWU Department of Health, Sport and Physical Education. She convinced Baker to let her do a research project on the selection process for the U.S. National Bobsled Team.

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Logic Models To Predict Continuous Outputs Based On Binary Inputs With An Application To Personalized Cancer Therapy., Theo A Knijnenburg, Gunnar W Klau, Francesco Iorio, Mathew J Garnett, Ultan Mcdermott, Ilya Shmulevich, Lodewyk F A Wessels Nov 2016

Logic Models To Predict Continuous Outputs Based On Binary Inputs With An Application To Personalized Cancer Therapy., Theo A Knijnenburg, Gunnar W Klau, Francesco Iorio, Mathew J Garnett, Ultan Mcdermott, Ilya Shmulevich, Lodewyk F A Wessels

Articles, Abstracts, and Reports

Mining large datasets using machine learning approaches often leads to models that are hard to interpret and not amenable to the generation of hypotheses that can be experimentally tested. We present 'Logic Optimization for Binary Input to Continuous Output' (LOBICO), a computational approach that infers small and easily interpretable logic models of binary input features that explain a continuous output variable. Applying LOBICO to a large cancer cell line panel, we find that logic combinations of multiple mutations are more predictive of drug response than single gene predictors. Importantly, we show that the use of the continuous information leads to …

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2016-November-23-Quillen Etsu Pediatrics, University Marketing And Communications, East Tennessee State University Nov 2016

2016-November-23-Quillen Etsu Pediatrics, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

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Abq Free Press, November 23, 2016, Abq Free Press Nov 2016

Abq Free Press, November 23, 2016, Abq Free Press

ABQ Free Press

No abstract provided.

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Volume 54, Number 15: November 23, 2016, University Of North Dakota Nov 2016

Volume 54, Number 15: November 23, 2016, University Of North Dakota

University Letter Archive

No abstract provided.

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Separation Trauma Nuggets, Warren L. Gleckel Ph.D., Reva M. Fish Ph.D. Nov 2016

Separation Trauma Nuggets, Warren L. Gleckel Ph.D., Reva M. Fish Ph.D.

NYS Child Welfare/Child Protective Services Training Institute

Contains 15 "Nuggets" which include narratives, power point presentations, and quizzes on separation trauma.

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Dopamine Effects Of Stimulant And Non-Stimulant Drugs Used In The Treatment Of Attention Deficit Hyperactivity Disorder, Preeti Chalwadi Nov 2016

Dopamine Effects Of Stimulant And Non-Stimulant Drugs Used In The Treatment Of Attention Deficit Hyperactivity Disorder, Preeti Chalwadi

Theses and Dissertations

Attention deficit hyperactivity disorder (ADHD) is thought to be associated with dysfunction of ascending catecholamine neuronal systems, particularly dopamine (DA) and norepinephrine (NE). Dysfunction of these catecholamine neurons innervating the prefrontal cortex is hypothesized to underlie impaired executive functions. Dysfunction of the DA neurons innervating the striatum is additionally hypothesized to underlie deficits in motivation and reinforcement learning. However, mechanisms of action of therapeutic drugs used for treating ADHD have mainly focused on catecholamines in the prefrontal cortex and have not adequately addressed the role played by DA signaling in the striatum. Stimulants such as Adderall® and Ritalin® are chemically …

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Whalesong 2016-11-23, N/A N/A Nov 2016

Whalesong 2016-11-23, N/A N/A

Whalesong

No abstract provided.

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Reply Brief. Lavigne V. Cajun Deep Foundations, L.L.C., 137 S.Ct. 1328 (2017) (No. 16-464), 2016 Wl 9443770, Eric Schnapper, J. Arthur Smith, Iii, Justin M. Delaune Nov 2016

Reply Brief. Lavigne V. Cajun Deep Foundations, L.L.C., 137 S.Ct. 1328 (2017) (No. 16-464), 2016 Wl 9443770, Eric Schnapper, J. Arthur Smith, Iii, Justin M. Delaune

Court Briefs

QUESTIONS PRESENTED (1) To establish a prima facie case of discriminatory termination, is a plaintiff required to show that he was replaced by someone outside his or her protected group?* (2) Under Title VII of the Civil Rights Act of 1964, a plaintiff prior to:bringing a civil action must first file a charge with the EEOC, usually within 300 days of the action complained of. The Question Presented is: Where a claimant files a timely Title VII charge asserting that employer conduct was the result of a particular unlawful motive, may the claimant after the end of the charge-filing period …

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The Limits Of Regulation: A Case Study Of Virtual And Intangible Harm, Nachshon Goltz Nov 2016

The Limits Of Regulation: A Case Study Of Virtual And Intangible Harm, Nachshon Goltz

PhD Dissertations

This dissertation deals with the limits of regulation through the analysis of virtual and intangible harm and the capacity of regulation to prevent or at least reduce such harm. The case study at hand is the potential harm to childrens imaginative development in virtual worlds. A comparison is drawn from the regulation of online advertising to children in Canada and the US. Based on a review of the literature in chapter 1, it is suggested that there are serious and long-term consequences to an underdeveloped imagination, including pathological phenomenon and lack of imaginative ability. As with other harms to children, …

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The Intestinal Copper Exporter Cua-1 Is Required For Systemic Copper Homeostasis In Caenorhabditis Elegans, Haarin Chun, Anuj Kumar Sharma, Jaekwon Lee, Jefferson Chan, Shang Jia, Byung-Eun Kim Nov 2016

The Intestinal Copper Exporter Cua-1 Is Required For Systemic Copper Homeostasis In Caenorhabditis Elegans, Haarin Chun, Anuj Kumar Sharma, Jaekwon Lee, Jefferson Chan, Shang Jia, Byung-Eun Kim

Department of Biochemistry: Faculty Publications

Copper plays key catalytic and regulatory roles in biochemical processes essential for normal growth, development, and health. Defects in copper metabolism cause Menkes and Wilson’s disease, myeloneuropathy, and cardiovascular disease and are associated with other pathophysiological states. Consequently, it is critical to understand the mechanisms by which organisms control the acquisition, distribution, and utilization of copper. The intestinal enterocyte is a key regulatory point for copper absorption into the body; however, the mechanisms by which intestinal cells transport copper to maintain organismal copper homeostasis are poorly understood. Here, we identify a mechanism by which organismal copper homeostasis is maintained by …

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Geiger V. Elliott Respondent's Brief Dckt. 44265 Nov 2016

Geiger V. Elliott Respondent's Brief Dckt. 44265

Not Reported

No abstract provided.

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The Effects Of Phytohormones And Isoprenoids In Dihydroartemisinin-Induced Dormancy In The Erythrocytic Stages Of Plasmodium Falciparum, Marvin Duvalsaint Duvalsaint Nov 2016

The Effects Of Phytohormones And Isoprenoids In Dihydroartemisinin-Induced Dormancy In The Erythrocytic Stages Of Plasmodium Falciparum, Marvin Duvalsaint Duvalsaint

USF Tampa Graduate Theses and Dissertations

Our ability to control malaria has been challenged by increasing antimalarial resistance. Plasmodium falciparum undergoes dormancy in the blood stages which is hypothesized to be a means by which they are able to survive under drug pressure. This helps select for resistant parasites which grow following removal of drug. The mechanisms behind dormancy and the subsequent recrudescence are not fully understood but translating knowledge from related organisms which undergo a similar phenomenon might shed some light. Higher plants utilize dormancy during the early development stages to survive under unfavorable conditions, increasing fitness of the seedling and ensuring viability when this …

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Why Therapists Bite Their Tongue In Therapy And What To Do About It, Ingibjorg Thors Nov 2016

Why Therapists Bite Their Tongue In Therapy And What To Do About It, Ingibjorg Thors

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Most therapists agree that therapy should be a place where the unspeakable is speakable, and the role of the therapist should be to help the client find a way to change by exploring the patterns of behavior that are no longer working for the client. Being blunt in therapy seems to be one of the key factors needed to promote immediacy, to challenge habitual ways of thinking that are not productive for our clients, and to create a relationship that is different from social and professional relationships. However, many therapists have distorted beliefs about using bluntness in therapy to stimulate …

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Circular Economy And System Thinking Framework In Design; Food System Design, Mehrafza Mirzazad Barijugh Nov 2016

Circular Economy And System Thinking Framework In Design; Food System Design, Mehrafza Mirzazad Barijugh

Theses

The purpose of this thesis is to bring the circular economy framework and system thinking into the process of design thinking. The traditional design process is made up of five steps: 1) Discover a challenge. 2) Interpret the challenge. 3) Create opportunities and ideas. 4) Develop a solution and experiment with it. 5) Evolve the idea. This project is structured upon a methodology generated to apply a circular system framework in design that begins with taking a holistic view of topic. This methodology structured into five phases. The first phase is referring to this approach as moving from Macrocosm to …

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The Use Of Official Statistics In Self-Selection Bias Modeling, L Dalla Valle Nov 2016

The Use Of Official Statistics In Self-Selection Bias Modeling, L Dalla Valle

School of Engineering, Computing and Mathematics

No abstract provided.

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Deposition Methods For Microstructured And Nanostructured Coatings On Metallic Bone Implants: A Review, Bailey Jordan Moore Nov 2016

Deposition Methods For Microstructured And Nanostructured Coatings On Metallic Bone Implants: A Review, Bailey Jordan Moore

Electronic Theses and Dissertations Archive

A review of current deposition processes is presented as they relate to osseointegration of metallic bone implants. The objective is to present a comprehensive review of different deposition processes used to apply microstructured and nanostructured osteoconductive coatings on metallic bone implants. Implant surface topography required for optimal osseointegration is presented. Five of the most widely used osteoconductive coating deposition processes are reviewed in terms of their microstructure and nanostructure, usable thickness and cost, all of which are summarized in tables and charts. Plasma spray techniques offer cost-effective coatings, but exhibits deficiencies with regard to osseointegration such as, high density, amorphous …

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Validity Of Methods In Measuring Resting Energy Expenditure In Pediatric Oncology Patients, Ashley Marie Hobar Nov 2016

Validity Of Methods In Measuring Resting Energy Expenditure In Pediatric Oncology Patients, Ashley Marie Hobar

Electronic Theses and Dissertations Archive

Evaluation of nutrition status is imperative for pediatric oncology patients due to prevalence of malnutrition and its effects. Methods used to evaluate nutrition status over- and underestimate energy needs. The purpose of the project was to determine if the Medgem and WHO predictive equations predict resting energy expenditure (REE) when compared to a traditional indirect calorimeter. Participants, 7-18 years of age, had testing completed on a traditional indirect calorimeter, Medgem, and energy estimation by WHO equation. Post hoc pairwise comparisons revealed all three methods were significantly different from one another (all p<0.0001), suggesting REE be measured by metabolic cart.

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Relationship Among Teacher Absenteeism, Evaluation Scores, And Satisfaction With Teaching At The Elementary School Level, Marilyn Denice Russell Nov 2016

Relationship Among Teacher Absenteeism, Evaluation Scores, And Satisfaction With Teaching At The Elementary School Level, Marilyn Denice Russell

Electronic Theses and Dissertations Archive

Teacher absenteeism is a growing problem in the United States.Teachers miss more days in the educational field than in any other workforce according to Cheng (2013). Educational leaders are beginning to pay close attention to the number of days teachers are missing as they seek waysto improve school effectiveness. Seven elementary schools were surveyed using Bentley and Rempels (1980) Purdue Teacher Opinionnaire to determine what relationships exist between 89 third through fifth gradeteachers in a small southwestern school district in Tennessee. This quantitative study addresses relationships in terms of teachers usage of sick and personal days, the teacher's professional TVAAS …

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The Influence Of Plant- And Animal-Based Diets On Testosterone And Lean Body Mass Is Male Rats, Damien Christopher Moore Nov 2016

The Influence Of Plant- And Animal-Based Diets On Testosterone And Lean Body Mass Is Male Rats, Damien Christopher Moore

Electronic Theses and Dissertations Archive

Background: It is commonly believed but unproven that plant-based diets result in low circulating testosterone, with minimal gains in lean body mass (LBM). Methods: Long-Evans rats (N=28) were assigned to experimental diets with either plant (PD) or animal (AD) protein sources. Animals were further divided into two additional conditions without and with exercise. Animals were fed ad libitum for 3 months and at the end of month three blood was collected for measurement of testosterone and estradiol concentrations. Dual x-ray absorptiometry assessed body composition. Results: Neither blood testosterone concentrations nor LBM differed between rats fed the PD or AD. Conclusion: …

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An Assessment Of College Tuition Increases And Retention, Raymond N. Karasek Iii Nov 2016

An Assessment Of College Tuition Increases And Retention, Raymond N. Karasek Iii

Electronic Theses and Dissertations Archive

This study examines the relationship between tuition increases, retention, and Pell Grant recipients attending college for the first time at 279 four-year public universities in the southeastern and southwestern regions of the United States. The data for this study was gathered from the Integrated Postsecondary Education System (IPEDS) using the tuition, retention, and Pell Grant information collected in the fall of those corresponding academic years. APearson moment correlation and linear regression analysis was used to find significance between the three variables. The study revealed that there was no significant interaction with student retention. However, the study did reveal a correlation …

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Experiential Avoidance, Depression, And Satisfaction With Life: The Moderational Role Of Regulatory Emotional Self-Efficacy, James E. Sweeney Nov 2016

Experiential Avoidance, Depression, And Satisfaction With Life: The Moderational Role Of Regulatory Emotional Self-Efficacy, James E. Sweeney

Electronic Theses and Dissertations Archive

Experiential Avoidance (a process of not accepting internal experiences and rigidly attempting to alter the form, frequency, or intensity of these experiences) has been related to a variety of negative outcomes, including heightened depression and decreased satisfaction with life. Because of this, factors that may buffer or account for the relationship between experiential avoidance and these outcomes should be examined. Regulatory emotional self-efficacy may be one important factor that moderates the relationship between experiential avoidance and outcomes, yet no studies have examined this possibility. The purpose of this study was to examine whether regulatory emotional self-efficacy and experiential avoidance interacted …

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From Markers To Interventions - The Case Of Just-In-Time Stress Intervention, Hillol Sarker Nov 2016

From Markers To Interventions - The Case Of Just-In-Time Stress Intervention, Hillol Sarker

Electronic Theses and Dissertations Archive

Wearable wireless sensors for health monitoring are enabling the design and delivery of just-in-time interventions (JITI). Critical to the success of JITI is to time its delivery so that the user is available to be engaged. This dissertation takes a first step in modeling users' availability by analyzing 2,064 hours of physiological sensor data and 2,717 self-reports collected from 30 participants in a week-long field study. Delay in responding to a prompt is used to objectively measure availability. Presented work compute 99 features and identify 30 as most discriminating to train a machine learning model for predicting availability. Findings suggest …

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A Principal Component Meta-Analysis On Multiple Anthropometric Traits Identifies Novel Loci For Body Shape, Janina S. Ried, Janina Jeff M., Audrey Y. Chu, Jennifer L. Bragg-Gresham, Jennifer E. Huffman, Tarunveer S. Ahluwalia, Gemma Cadby, Niina Eklund, John Blangero Nov 2016

A Principal Component Meta-Analysis On Multiple Anthropometric Traits Identifies Novel Loci For Body Shape, Janina S. Ried, Janina Jeff M., Audrey Y. Chu, Jennifer L. Bragg-Gresham, Jennifer E. Huffman, Tarunveer S. Ahluwalia, Gemma Cadby, Niina Eklund, John Blangero

School of Medicine Publications

Large consortia have revealed hundreds of genetic loci associated with anthropometric traits, one trait at a time. We examined whether genetic variants affect body shape as a composite phenotype that is represented by a combination of anthropometric traits. We developed an approach that calculates averaged PCs (AvPCs) representing body shape derived from six anthropometric traits (body mass index, height, weight, waist and hip circumference, waist-to-hip ratio). The first four AvPCs explain >99% of the variability, are heritable, and associate with cardiometabolic outcomes. We performed genome-wide association analyses for each body shape composite phenotype across 65 studies and meta-analysed summary statistics. …

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Exploring Shame And Guilt In Hiv-Positive Women In Southern India, Mitra L. Lebastchi Nov 2016

Exploring Shame And Guilt In Hiv-Positive Women In Southern India, Mitra L. Lebastchi

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Limited research exists examining shame and guilt among HIV positive populations and across cultural contexts. This study addresses this gap in the literature by considering shame and guilt, and potential associations with mental health symptoms, among a sample of 20 HIV positive women in Southern India. Results indicate that most women experienced high levels of shame and guilt, based on responses to items from an adapted version of the State Shame and Guilt Scale (Marschall, Saftner, & Tangney, 1994). Although correlations were not significant between shame and PTSD or depression, guilt was significantly correlated with both. Future research should focus …

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Mitochondrial Heteroplasmy Contributes To The Dynamic Atovaquone Resistance Response In Plasmodium Falciparum, Sasha Victoria Siegel Nov 2016

Mitochondrial Heteroplasmy Contributes To The Dynamic Atovaquone Resistance Response In Plasmodium Falciparum, Sasha Victoria Siegel

USF Tampa Graduate Theses and Dissertations

Of the considerable challenges researchers face in the control and elimination of malaria, the development of antimalarial drug resistance in parasite populations remains a significant hurdle to progress worldwide. Atovaquone is used in combination with proguanil (Malarone) as an antimalarial treatment in uncomplicated malaria, but is rendered ineffective by the rapid development of atovaquone resistance during treatment. Previous studies have established that de novo mutant parasites confer resistance to atovaquone with a substitution in amino acid 268 in the cytochrome b gene encoded by the parasite mitochondrial genome, yet much is still unknown about how this resistance develops, and whether …

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Tingkat Kecukupan Dan Bioavailabilitas Asupan Zat Besi Pada Ibu Hamil Di Kota Tangerang, Yuni Pradilla Fitri, Dodik Briawan, Ikeu Tanziha, Siti Madanijah Nov 2016

Tingkat Kecukupan Dan Bioavailabilitas Asupan Zat Besi Pada Ibu Hamil Di Kota Tangerang, Yuni Pradilla Fitri, Dodik Briawan, Ikeu Tanziha, Siti Madanijah

Media Kesehatan Masyarakat Indonesia

Anemia merupakan masalah kesehatan masyarakat yang masih umum dijumpai. Sebagian besar anemia pada ibu hamil disebabkan oleh defisiensi zat besi. Penelitian ini secara umum bertujuan menganalisis kecukupan dan bioavailabilitas asupan zat besi pada ibu hamil di Kota Tangerang. Penelitian ini menggunakan desain cross-sectional. Wawancara mengenai konsumsi pangan dilakukan kepada 91 orang ibu hamil pada bulan Februari sampai Juni 2015 menggunakan food frequency questionnaire semi-kuantitatif. Hasil penelitian menunjukkan bahwa 97,8% ibu hamil memiliki tingkat kecukupan zat besi yang berada dalam kategori kurang. Seluruh ibu hamil memiliki bioavailabilitas besi dalam kategori rendah. Terdapat hubungan signifikan antara frekuensi konsumsi nasi (p=0,000), kacang-kacangan (p=0,000), …

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Faktor Risiko Stunting Pada Anak Usia 6-24 Bulan Di Kota Bogor, Erni Rukmana, Dodik Briawan, Ikeu Ekayanti Nov 2016

Faktor Risiko Stunting Pada Anak Usia 6-24 Bulan Di Kota Bogor, Erni Rukmana, Dodik Briawan, Ikeu Ekayanti

Media Kesehatan Masyarakat Indonesia

Pertumbuhan anak merupakan salah satu indikator status gizi dan kesehatan dalam populasi untuk mencerminkan kualitas sumber daya manusia. Stunting yaitu pertumbuhan linier yang terhambat dan merupakan hasil dari ketidakcukupan gizi dalam jangka waktu lama. Penelitian ini bertujuan untuk menganalisis faktor-faktor risiko stunting pada anak usia 6-24 bulan di Kota Bogor. Penelitian ini merupakan desain crossectional dengan subjek 360 anak usia 6-24 bulan di Kota Bogor. Teknik pengumpulan data menggunakan kuesioner yang terdiri dari keadaan sosial ekonomi orang tua, yaitu pendidikan, pekerjaan, dan pendapatan. Berat badan dan panjang badan lahir berdasarkan data yang diambil dari KMS dan buku KIA. Data yang …

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The Relationship Between Chewing Food And Sleeping Disorders Caused By Dental And Oral Diseases To Preschool Children’S Food Intake, Ristya Widi Endah Yani Nov 2016

The Relationship Between Chewing Food And Sleeping Disorders Caused By Dental And Oral Diseases To Preschool Children’S Food Intake, Ristya Widi Endah Yani

Media Kesehatan Masyarakat Indonesia

Food intake is a directly influential factor in determining nutritional status of preschool children. Dental and oral diseases generally cause pain in teeth which make them have difficulty to eat and sleep well. This situation can result in reduced food intake. The research objective was to analyze the relationship between chewing food and sleeping disorders caused by dental and oral diseases to preschool children’s food intake. An analytic observational study with cross sectional design in preschool age children was conducted in District Ambulu, Jember Regency. A hundred and two samples were taken using purposive sampling method. The variables studied were …

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Anak Dan Jajanan Sekolah: Program Pemberdayaan Kesehatan Anak Sekolah Dalam Perspektif Pemerintah Daerah, Anna Triwijayati, Etsa Astridya Setiyati, Yudi Setianingsih, Maria Lucia Luciana Nov 2016

Anak Dan Jajanan Sekolah: Program Pemberdayaan Kesehatan Anak Sekolah Dalam Perspektif Pemerintah Daerah, Anna Triwijayati, Etsa Astridya Setiyati, Yudi Setianingsih, Maria Lucia Luciana

Media Kesehatan Masyarakat Indonesia

Pemberdayaan anak akan konsumsi makanan jajanan di sekolah merupakan upaya untuk memastikan anak mampu mengambil keputusan konsumsi dengan tepat dan terlindung dari bahaya jajanan yang tidak sehat. Upaya tersebut antara lain menjadi tanggungjawab pemerintah pusat dan daerah. Penelitian ini menggunakan metode kualitatif melalui focus group discussion dengan instansi pemerintah, yaitu Balai Besar Pengawas Obat dan Makanan di Surabaya, Dinas Kesehatan Kota dan Kabupaten Malang serta Dinas Perindustrian dan Perdagangan Kota dan Kabupaten Malang. Hasil diskusi menunjukkan bahwa pemerintah mengambil peran mengatur regulasi yang berkaitan dengan sekolah, kantin dan Pedagang Kaki Lima (PKL) terkait dengan jajanan sehat untuk anak. Namun, di …

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