Digital Commons Network^™

Propiedad Intelectual Y Acceso A Medicamentos: El Caso De Lopinavir/Ritonavir En Guatemala, Luis Pablo Méndez-Alburez, Alejandro Cerón

Anthropology: Faculty Scholarship

No abstract provided.

Salvation By Statute: Magna Carta, Legislation, And The King’S Soul, Thomas J. Mcsweeney

William & Mary Bill of Rights Journal

No abstract provided.

Design Of A Clinical Competency Committee To Maximize Formative Feedback., Anthony A. Donato, Richard Alweis, Suzanne Wenderoth

Reading Hospital Internal Medicine Residency

BACKGROUND: As the next phase in the roll-out of Next Accreditation System, US residency programs are to develop Clinical Competency Committees (CCCs) to formally implement outcome-based medical education objectives in the resident assessment process. However, any changes to an assessment system must consider balancing formative and summative tensions, flexibility and standardization tensions, fairness and transparency to learners, and administrative burden for faculty.

OBJECTIVES/METHODS: In this article, one program discusses the approach one internal medicine residency took to create a developmental model CCC. In this model, a learner's mentor presents the argument for competence to the CCC, while a second reviewer …

Rental Home Sweet Home: The Disparate Impact Solution For Renters Evicted From Residential Foreclosures, David Lurie

Northwestern University Law Review

At the end of the last decade, a drastic spike in residential foreclosures brought unprecedented attention to the damage that mass foreclosure often brings to primarily low-income, minority–majority communities. Much of this attention—in both the media and in the legal arena—has been devoted to homeowners disadvantaged by predatory loans and other unsavory practices. However, a recent body of scholarship has shown that the brunt of mass foreclosure often falls on renters, who often have little or no procedural protection from speedy and unexpected eviction from their homes, regardless of lease status or tenure. This Note argues that the Supreme Court’s …

Is There Moral Hazard In The Heavily Indebted Poor Countries (Hipc) Initiative Debt Relief Process?, Joshua C. Hall, Serkan Karadas, Minh Tam T. Schlosky

Economics Faculty Working Papers Series

The Heavily Indebted Poor Countries (HIPC) Initiative and the Multilateral Debt Relief Initiative (MDRI) were created by the IMF and World Bank to help low-income countries reduce their debt burden and to facilitate reaching the Millennium Development Goals. After entering the decision point of the HIPC Initiative stage, countries receive interim aid while following a strategic path to improve their macroeconomic stability via structural reforms. Many countries reached the completion point of the HIPC Initiative stage within a few years, receiving a substantial amount of debt re- lief. Other countries remained in the interim period for almost a decade. We …

The Interaction Of Mercury And Methylmercury With Reduced Sulfur: Implications For The Transformation Of Mercury And Methylmercury In The Environment, Nashaat M. Mazrui

Doctoral Dissertations

Archival abstract submitted

Passive Radio Frequency Identification (Rfid) And Museum Collections, Owen Kinser

Master's Projects and Capstones

Keeping a collection organized and accounted for is a never-ending struggle for museums of every type. New to museums and the collections management field, Radio Frequency Identification is a growing technology that museums can implement to keep track of the location, status, condition, and movement of their objects. Objects are labeled with RFID “tags” which enable them to communicate custom information to a reader and ultimately a database. This implementation would save time, money, and stress among collections staff members. Using the Perot Museum of Nature and Science in Dallas, Texas, as my subject museum, I propose implementing a pilot …

Access Is Meaningful (Aim): Working With Community Health Centers To Improve Access To Care., Tammy Toscos Phd, Maria D. Carpenter Rn, Bsn, Kislaya Kunjan Ms, Mba, Iman Mohammadi Ms, Amy Miller, Brad N. Doebbeling Md, Ms, Huanmei Wu Phd

Health Services and Informatics Research

Presented in 9th Annual Conference on the Science of Dissemination and Implementation

Background:

We are partnering with community health centers (CHCs) and their patients to redesign systems to deliver timely care to underserved populations in Indiana. Our Delphi study was designed to address two questions: 1) what solutions (e.g. organizational factors, processes, procedures) serve as facilitators to accessing care?; and 2) what organizational strategies might work to implement solutions in CHC environments?

Methods:

We used a modified Delphi method, bringing experts together in one room for a face-to-face meeting to prioritize solutions for reducing access barriers and strategies to implement …

Breaking Barriers: Saudi Women In Non Traditional Careers, Suad Dukhaykh

Student Scholarship

Women occupy only 15.8 percent of the private and public positions occupied by Saudi nationals, according to statistics from the Central Department of Statistics and Information 2015. The Saudi government has highlighted the need to support women's higher education and combat sociopolitical barriers to their employment. Despite facing substantial challenges to entering the labor market, females have made gains in Saudi society; these include higher literacy rates, greater employment, and moderate rates of entry into both positions of leadership and nontraditional careers. Qualitative research was based on semi-structured interviews with 30 women, 18 of whom had nontraditional careers and 12 …

Towards Clinical Photoacoustic Imaging: Developing Next-Generation Endoscopy Systems And Exploring New Contrast Agents, Chiye Li

McKelvey School of Engineering Graduate Student Theses & Dissertations

Photoacoustic imaging holds great clinical promise because it achieves high-resolution tomographic imaging at depths. Moreover, its strong spectroscopic imaging capability provides a wealth of molecular and functional information based on. Still, despite recent advances, existing photoacoustic systems cannot be readily applied in the clinical environment. This dissertation aims to push the frontier of clinical photoacoustic imaging from both technological and applicational perspectives.

The first part of this dissertation describes the development of photoacoustic endoscopy (PAE) systems for imaging human Barrett's esophagus and studying preterm birth. We have developed optical resolution-PAE, which significantly improved lateral resolutions, laparoscopic-PAE, which can guide minimally-invasive …

Discovery And Characterization Of A Novel Class Of Metabolic Regulators In The Malaria Parasite Plasmodium Falciparum, Ann Marie Guggisberg

Arts & Sciences Graduate Student Theses and Dissertations

The malaria parasite, Plasmodium falciparum, infects hundreds of millions of people per year and causes hundreds of thousands of deaths. Within the host red blood cell, the parasite relies on glycolysis for energy and synthesis of essential biomolecules. One such anabolic fate of glucose is the synthesis of isoprenoids, a broad and essential class of compounds that participate in a variety of cellular functions. In the face of ever-evolving drug resistance, new inhibitors and better understanding of parasite metabolism are required. The antibiotic fosmidomycin (FSM) targets the methylerythritol phosphate pathway for isoprenoid synthesis and is a well-validated inhibitor of P. …

Novel Regulation Of The Nonsense-Mediated Rna Decay Pathway, Andrew Keith Nickless

Arts & Sciences Graduate Student Theses and Dissertations

The nonsense mediated RNA decay (NMD) pathway maintains the integrity of cellular RNAs and controls gene expression. NMD is essential for vertebrate development and defects in NMD are associated with a variety of neurodevelopmental disorders and cancers. NMD activity is tightly regulated and is altered in response to environmental and developmental signals. To better study this dynamic pathway and to identify clinically relevant regulators of its activity, we developed a dual-color bioluminescent NMD reporter that rapidly and accurately quantifies NMD activity in mammalian cells. Using this reporter, we performed a chemical screen for small-molecule modulators of NMD activity and identified …

Neural Dynamics Tracking Subjective Cognitive Effort, John Andrew Westbrook

Arts & Sciences Graduate Student Theses and Dissertations

What patterns of brain activity reflect engagement with highly demanding cognitive tasks? How do these patterns relate to subjective, phenomenal effort? Answering these questions is critical to understanding what causes some people to experience cognitive tasks as more effortful than others. Subjective experience, in turn, is vital, with trait tendencies to exert effort having been linked to career and academic success. High subjective effort, as in schizophrenia and depression, can thus be extremely problematic. And yet, poor operational definitions have constrained research into basic questions about what neural dynamics track subjective effort. Here, a powerful, new behavioral economic operationalization is …

Ongoing And Visually-Evoked Cortical Activity Measured Across Multiple Spatial Scales, Nathaniel Caleb Wright

Arts & Sciences Graduate Student Theses and Dissertations

The visual cortex is a densely-interconnected network of neurons, which receives sensory input from the early visual pathway, and represents information about the visual world in the resulting spatiotemporal activity patterns. These patterns are mediated by cortical interactions that span multiple spatial scales (i.e., neuron-neuron, neuron-population, and population-population). Such interactions are a fundamental property of cortical function, and capture the contribution of the cortex to sensory coding. Yet these interactions are only beginning to be understood, in part because of the challenge of recording ongoing and visually-evoked activity across multiple spatial scales in individual studies. In this thesis, we present …

The Human Arf Tumor Suppressor Regulates Drosha Nucleolar Localization And Rrna Processing Activity, Sree Chandana Sridhar Yaddanapudi

Arts & Sciences Graduate Student Theses and Dissertations

Ribosomes are vital to the survival of a cell, as they are directly responsible for the synthesis of proteins, which perform critical cellular functions. As such, majority of the energy reserves in a proliferating cell are expended towards synthesis of ribosomes. Cancer cells, with their enhanced proliferation rates, tend to upregulate ribosome biogenesis in order to meet the demand for increased protein synthesis necessary to sustain rapid proliferation. Many of the oncogenes and tumor suppressors known to be deregulated in cancers are capable of positively and negatively regulating ribosome biogenesis, respectively. The ARF tumor suppressor strongly suppresses ribosome biogenesis, particularly …

Essays In Entrepreneurship And Household Finance, Yoosef Ghahreman

Arts & Sciences Graduate Student Theses and Dissertations

My dissertation is focused on the relationship between financial and business decisions of households. The first essay examines how founders of new businesses changed their portfolios in the aftermath of the 2007-2008 financial crisis. Using the Survey of Consumer Finances 2007-2009 panel data, I find evidence that those who became entrepreneurs (entrants) reduced financial portfolio risk compared to those who remained paid employees. I identify a movement away from stockholdings as a result of entry, and provide support for a response to the background risk arising from privately held businesses. Business ownership was also associated with changes in the real …

Pleasure In The Past: Queer Nostalgia In The Gay American Century, Elisabeth Windle

Arts & Sciences Graduate Student Theses and Dissertations

In this dissertation, I recover nostalgia—unpopular, too frequently dismissed, and presumptively conservative—as a generative emotional position from which to read queer texts. My archive assembles a group of post-Stonewall texts—literature, film, television, and advertising—that marshal the pre-Stonewall literary past to support reflection on the pressing issues of recent gay life: same-sex marriage, the myth of the down low, effemiphobia and anti-feminism, and HIV/AIDS. Shuttling critically between modernist literary history and contemporary culture, I propose nostalgia as a useful affective mode for negotiating our relationship to queer history. Against both the pervasive narrative of gay progress circulating in mainstream culture and …

Health-Related Quality Of Life In Older Coastal Residents After Multiple Disasters, Katie E. Cherry, Laura Sampson, Sandro Galea, Loren D. Marks, Kayla H. Boudoin, Pamela F. Nezat, Katie E. Stanko

Faculty Publications

Objective: Exposure to multiple disasters, both natural and technological, is associated with extreme stress and long-term consequences for older adults that are not well understood. In this article, we address age differences in health-related quality of life in older disaster survivors exposed to the 2005 Hurricanes Katrina and Rita and the 2010 BP Deepwater Horizon oil spill and the role played by social engagement in influencing these differences.

Methods: Participants were noncoastal residents, current coastal residents, and current coastal fishers who were economically affected by the BP oil spill. Social engagement was estimated on the basis of disruptions in charitable …

Kinder Ready: Exploring The Role Of Technology In Promoting School Readiness Among Low-Income Parents In A Clinic-Based Setting, Brenda Lu

Master's Projects and Capstones

The Stanford Pediatric Advocacy Program advocates to improve the health status of children in Silicon Valley and the surrounding community. This summer, I worked on a project called Kinder Ready, with the goal of evaluating the feasibility of technology use in promoting school readiness in children ages zero to five. We used a variety of qualitative research methods, including focus groups, one-on-one interviews, and surveys to collect feedback from the community on what their children need to transition into schools. Our local participatory research approach has paved the way for many new partnerships with local organizations, while strengthening existing ones. …

Falls Program On An Acute Psychiatric Unit, Joseph Hunter Rose

Master's Projects and Capstones

In the metropolitan hospital’s acute psychiatric unit there has been an increase in falls incidence as well as need for evaluation of the effectiveness of Schmid Fall Risk Assessment tool in its ability to properly identify those at risk. In the last fiscal year there were 45 falls among 28 patients on the acute psychiatric unit.Falls are harmful to the patients and can cause prolonged hospital stays with non-reimbursable costs to the hospital. Falls amongst psychiatric patients is an even greater challenge to address due to the nature of the mental health disease process. This project addresses general costs of …

Bullying Experiences And Resilience In Lgbtq Youth, Melinda Mccormick

Dissertations

Many young LGBTQ people are experiencing bullying which can lead to increased risk of suicide, drug abuse, and depression, as well as an increased risk of out-of-home placements in either foster care or homeless shelters. As a result of this, LGBTQ young adults are often framed as being at risk. Although this has been helpful in the past in order to raise awareness of the challenges experienced by LGBTQ young people, there is also evidence that they show resilience in response to those challenges. In order to advance the social work value of being strengths-based, this research looked for examples …

Virile, Yet Feminine: Sport, Gender, And Representation In Fascist Italy, Andrea Dlugos

Historical Perspectives: Santa Clara University Undergraduate Journal of History, Series II

No abstract provided.

The Development, Impact, And Long-Term Significance Of Wartime Propaganda On The Doughboys In World War I: Personal Appeal Vs.Moral Imperative, Maggie Woods

Historical Perspectives: Santa Clara University Undergraduate Journal of History, Series II

No abstract provided.

Protecting The Dead Or Protecting The Living? Above Ground Interment In Georgian (1714-1830) And Victorian Britain (1837-1901), Maxine Devincenzi

Historical Perspectives: Santa Clara University Undergraduate Journal of History, Series II

No abstract provided.

Creators, Destroyers, And A Judge: Infanticide And Puerperal Insanity In Victorian English Courts, Christina Forst

Historical Perspectives: Santa Clara University Undergraduate Journal of History, Series II

No abstract provided.

Historical Perspectives Vol. 17 2012

Historical Perspectives: Santa Clara University Undergraduate Journal of History, Series II

No abstract provided.

Biblical Foundations For Nutrition And An Abundant Life, Elizabeth Snyder, M.A.

The Journal of Biblical Foundations of Faith and Learning

The purpose of this paper is to look at what the Bible says about the significance of nutrition, its effect on health, and the benefits of a Christian-worldview on nutritional wellbeing. With the help of the Holy Spirit, nutrition teachers need to connect the science with the Biblical foundation God has given us in His word. While it is crucial to remember that salvation is through Christ alone, it is wise to recognize the connection between diet and frontal lobe function, where analytical, moral decisions are made. Studying and understanding what the Bible says about the original diet, clean vs. …

The Biblical Foundation For Social Workers As “Shepherds” Who Care For God’S Flock, Lorri Merchant, M.S.W.

The Journal of Biblical Foundations of Faith and Learning

The purpose of this paper is to reveal biblical foundations of caring for people in the context of professional social work practice. To accomplish this, the paper first identifies principles of caring as articulated in the accounts of shepherds and shepherding found in the Bible. Shepherding and the “Good Shepherd” discourse provide the biblical foundation for understanding what it means to care for others. Second, the core values of the social work profession are examined alongside the biblical principles, as they provide a professional foundation for the care social workers provide their clients. Third, overall biblical principles are compared with …

Building Biblically Founded Faith And Values Through A Campus-Wide Healthy Lifestyle Project, Holly Gadd, Ph.D., Lillian Tryon, D.N.P.

The Journal of Biblical Foundations of Faith and Learning

Essential to Seventh-day Adventist education is the development and strengthening of a biblically founded faith as a result of the student’s program of study and extracurricular activities. Much of Jesus’ ministry involved teaching. The goal of His teaching was to clearly reveal God’s love to a fallen world (John 17:6, 23 New International Version). At the end of His ministry, Jesus commissioned His followers to “preach the gospel” (Mark 16:15) and to “make disciples of all nations” (Matthew 28:19). As Seventh-day Adventist educators, we are commissioned by God to help our students reach not just career goals, but goals set …

Gideon’S Fleece: A Biblical Narrative Providing A Framework For Discussion Of Issues In The Relationship Between Scientific Inquiry And Divine Revelation, Brent Hamstra, Ph.D.

The Journal of Biblical Foundations of Faith and Learning

The story of Gideon’s attempt to determine God’s will by placing a fleece on the ground overnight and observing its moisture content relative to the surrounding ground, given in Judges 6:36-40, provides a framework for the discussion of several issues related to scientific inquiry and its relationship to divine activity and revelation. Issues noted in this paper include proper experimental design and execution, the manner in which God interacts with nature, human expectations of God’s interactions with nature, the roles of general and special revelation in knowing God’s past, present, and future activity, and the contrast between faith based on …