Digital Commons Network^™

Metabolomics Enables Precision Medicine: “A White Paper, Community Perspective”, Richard D. Beger, Warwick B. Dunn, Michael A. Schmidt, Steven S. Cross, Jennifer A. Kirwan, Marta S. Cascante, Lorraine Brennan, David S. Wishart, Matej Orešič, Thomas Hankemeier, David Broadhurst, Andrew N. Lane, Karsten Suhre, Gabi Kastenmüller, Susan J. Sumner, Ines Thiele, Oliver E. Fiehn, Rima Kaddurah- Daouk

Research outputs 2014 to 2021

Introduction:Background to metabolomics:

Metabolomics is the comprehensive study of the metabolome, the repertoire of biochemicals (or small molecules) present in cells, tissues, and body fluids. The study of metabolism at the global or “-omics” level is a rapidly growing field that has the potential to have a profound impact upon medical practice. At the center of metabolomics, is the concept that a person’s metabolic state provides a close representation of that individual’s overall health status. This metabolic state reflects what has been encoded by the genome, and modified by diet, environmental factors, and the gut microbiome. The metabolic profile provides …

Re-Conceptualising Graduate Employability: The Importance Of Pre-Professional Identity, Denise Jackson

Research outputs 2014 to 2021

Despite efforts to broaden the concept of graduate employability, there remains an overarching focus on developing industry-relevant employability skills. The skills-based approach is, however, too narrow and does not fully capture the complexity of graduate work-readiness. This paper argues for the redefining of graduate employability by embracing pre-professional identity (PPI) formation. PPI relates to an understanding of and connection with the skills, qualities, conduct, culture and ideology of a student's intended profession. The ‘communities of practice’ model is drawn upon to demonstrate how PPI can be developed during university years. Here, a student makes sense of his/her intended profession through …

Permanent Slides For Morphological Studies Of Small Crustaceans: Serban's Method And Its Variation Applied On Bathynellacea (Malacostraca), Giulia Perina, Ana I. Camacho

Research outputs 2014 to 2021

Morphological studies of small invertebrates often involve the preparation of slides to observe minute body parts under a compound microscope. Preparation should facilitate observation, through traditional optical microscopy, of small surface structures on different planes, like pores, spines and setae. Various methods and techniques, using different mounting media that specialists have adopted to observe and preserve small crustaceans, have their advantages and disadvantages.Within the order Bathynellacea, specimens in the family Bathynellidae are particularly challenging due to their small size (0.5 to 2.25 mm body length) and very delicate exoskeleton, which tends to be completely digested when using common clearing mounting …

The Influence Of The Sex Of And Prior Relationship Between The Perpetrator And Victim On Perceptions Of Stalking: A Qualitative Analysis, Jeff Bath, Adrian J. Scott

Research outputs 2014 to 2021

The sex of and prior relationship between the perpetrator and victim have been shown to influence perceptions of stalking. To explore the ways in which shared assumptions around these factors interact to shape perceptions of stalking, this study analyses the deliberations of mock juries as they attempt to reach a unanimous verdict on a hypothetical stalking case summary. Twelve mock juries comprising between five and six ‘jurors’ (n = 64) were presented with one of three versions of a case summary (stranger, acquaintance, and ex-partner) describing a man stalking a woman or a woman stalking a man. Thematic analysis shows …

Carbon Uptake And Water Use In Woodlands And Forests In Southern Australia During An Extreme Heat Wave Event In The "Angry Summer" Of 2012/2013, Eva Van Gorsel, Sebastian Wolf, James Cleverly, Peter Isaac, Vanessa Haverd, Caecilia M. Ewenz, Stefan Arndt, Jason Beringer, Victor R. De Dios, Bradley John Evans, Anne Griebel, Lindsay B. Hutley, Trevor F. Keenan, Natascha Kljun, Craig Macfarlane, Wayne S. Meyer, Ian Mchugh, E. G. Pendall, Suzanne M. Prober, Richard P. Silberstein

Research outputs 2014 to 2021

As a result of climate change warmer temperatures are projected through the 21st century and are already increasing above modelled predictions. Apart from increases in the mean, warm/hot temperature extremes are expected to become more prevalent in the future, along with an increase in the frequency of droughts. It is crucial to better understand the response of terrestrial ecosystems to such temperature extremes for predicting land-surface feedbacks in a changing climate. While land-surface feedbacks in drought conditions and during heat waves have been reported from Europe and the US, direct observations of the impact of such extremes on the carbon …

Models For Community Based Day Care For Older People: A Narrative Review, Caroline Bulsara, Christopher Etherton-Beer, Rosemary Saunders

Research outputs 2014 to 2021

Objectives:

Older Australians are choosing to live within the community and there are a number of initiatives to enable this sector of the population to do so for longer. In an effort to ensure that they remain both physically and psychologically engaged, one initiative has been to provide community based day care (CBDC).

Method:

A narrative review was undertaken through searching MEDLINE, CINAHL Plus, Scopus and AgeInfo using keywords related to facility related, target group related and purpose/program of CBDC services.

Results:

Results indicated that there is a much research investigating different approaches but little consensus regarding the optimal delivery …

Motor Subtype As A Predictor Of Future Working Memory Performance In Idiopathic Parkinson's Disease, Andrew R. Johnson, Romola S. Bucks, Robert T. Kane, Meghan G. Thomas, Natalie Gasson, Andrea M. Loftus

Research outputs 2014 to 2021

Parkinson’s disease is a progressive neurodegenerative disorder associated with reduced spatial and verbal working memory ability. There are two established motor subtypes of PD, tremor dominant (TD) and postural instability and gait difficulty (PIGD). This study used structural equation modelling to explore the longitudinal relationship between the two subtypes and working memory assessed at a 2-year follow-up. The study comprised 84 males and 30 females (N = 114), aged between 39 and 85 (M = 64.82, SD = 9.23) with confirmed PD. There was no significant relationship between motor subtype at Time 1 and working memory at Time 2. Postural …

Designing Journalism Capstone Units That Demonstrate Student Skills, Trevor Cullen

Research outputs 2014 to 2021

There are considerable differences in the structure, content, and delivery of tertiary journalism degrees in Australia as identified in a 2014 Office for Learning and Teaching (OLT) Innovation and Development Project report on graduate qualities and journalism curriculum renewal. To address this situation, the author argues for journalism capstone units, designed by both journalism educators and news editors, to include a series of agreed criteria and standards to guide journalism educators, and for journalism students to demonstrate not only a broad knowledge base together with research and communication skills but also entrepreneurial skills to help them adapt to new media …

Towards A Participatory Netnography: Collaborating With Children In Virtual Worlds Research, Ashley Donkin, Donell Holloway, Lelia Green

Research outputs 2014 to 2021

The new sociology of childhood has encouraged social researchers to incorporate children in as much of the research process as possible. However, whilst some success has been achieved within traditional ethnographic studies, netnography has been slow to make this a reality. This article discusses the previous online research into children’s virtual worlds, which has rarely incorporated young children into the data collection or research analysis processes. The opportunity for researchers to use participatory approaches to collaborating with their child participants and collecting online data is limited due to ethical constraints. The ethical challenges of conducting netnography are compounded by a …

Headline Grabs For Music: The Development Of An Ipad Score Generator, Cat Hope, Stuart James, Aaron Wyatt

Research outputs 2014 to 2021

This paper-demonstration provides an overview of an generative music score adapted for the iPad by the Decibel new music ensemble. The original score `Loaded (NSFW)’ (2015) is by Western Australian composer Laura Jane Lowther, and is scored for ensemble and electronics, commissioned for a performance in April 2015 at the Perth Institute of Contemporary Arts. It engages and develops the Decibel Score Player application, a score reader and generator for the iPad as a tool for displaying an interactive score that requires performers to react to news headlines through musical means. The paper will introduce the concept for the player, …

The Possibilities Of A Line: Marking The Glissando In Music, Cat Hope, Michael Terren

Research outputs 2014 to 2021

The glissando as it is deployed in Western art music notation carries with it a number of challenges to the hegemony of traditional harmony, rhythm, and notation. The glissando embodies the smooth line, unlike the striated pitch-time space of traditional Western music, which aligns the glissando to many philosophical concepts, as well as mathematical, scientific, and architectural disciplines. Select works by Iannis Xenakis, James Tenney and Giacinto Scelsi are discussed for their development of glissandi as integral formal components, especially around the glissando’s tendency to encourage stasis. Compositional attempts to combine the nature of glissandi with drone in the author’s …

Type 3 Diabetes With Links To Nafld And Other Chronic Diseases In The Western World, Ian J. Martins

Research outputs 2014 to 2021

In the year 2015 it is now estimated that 30% of the Western World will now progress to non alcoholic fatty liver disease (NAFLD) and by the year 2050 if NAFLD remains untreated in the Western world the prevalence of the disease may rise to 40% of the global population. Type 3 diabetes and circadian rhythm disturbances may be involved in the induction of NAFLD that may promote insulin resistance and various chronic diseases such as cardiovascular disease, pancreatic disease, kidney disease and neurodegenerative disease. Multiple risk factors that induce Type 3 diabetes and NAFLD include stress, magnesium deficiency, bacterial …

Controlled Access To Cloud Resources For Mitigating Economic Denial Of Sustainability (Edos) Attacks, Zubair A. Baig, Sadiq M. Sait, Farid Binbeshr

Research outputs 2014 to 2021

Cloud computing is a paradigm that provides scalable IT resources as a service over the Internet. Vulnerabilities in the cloud infrastructure have been readily exploited by the adversary class. Therefore, providing the desired level of assurance to all stakeholders through safeguarding data (sensitive or otherwise) which is stored in the cloud, is of utmost importance. In addition, protecting the cloud from adversarial attacks of diverse types and intents, cannot be understated. Economic Denial of Sustainability (EDoS) attack is considered as one of the concerns that has stalled many organizations from migrating their operations and/or data to the cloud. This is …

Stick Or Switch: A Selection Heuristic Predicts When People Take The Perspective Of Others Or Communicate Egocentrically, Shane Rogers, Nicholas Fay

Research outputs 2014 to 2021

This paper examines a cognitive mechanism that drives perspective-taking and egocentrism in interpersonal communication. Using a conceptual referential communication task, in which participants describe a range of abstract geometric shapes, Experiment 1 shows that perspective-taking and egocentric communication are frequent communication strategies. Experiment 2 tests a selection heuristic account of perspective-taking and egocentric communication. It uses participants' shape description ratings to predict their communication strategy. Participants' communication strategy was predicted by how informative they perceived the different shape descriptions to be. When participants' personal shape description was perceived to be more informative than their addressee's shape description, there was a …

Women Business Owners’ Start-Up Motivations And Network Content, Jalleh Sharafizad, Alan Coetzer

Research outputs 2014 to 2021

Purpose

The purpose of this paper is to examine how women small business owners’ (SBOs) business start-up motivations influence their network content.

Design/methodology/approach

Semi-structured interviews were conducted with 28 women SBOs who were recruited through purposeful sampling methods. Interview data on their start-up motivations were used to categorise them into three types: classic, forced and work-family. The interviews explored the network contents of the three categories of participants.

Findings

There were many similarities between network contents of classic and forced SBOs, as both groups had started their business for financial reasons rather than family reasons. All the participants’ networks contained …

Protocol For Care After Lymphoma (Caly) Trial: A Phase Ii Pilot Randomised Controlled Trial Of A Lymphoma Nurse-Led Model Of Survivorship Care, Karen Taylor, David Joske, Max Bulsara, Caroline Bulsara, Leanne Monterosso

Research outputs 2014 to 2021

Introduction:

Lymphoma is the sixth most common cancer diagnosed in Australia and internationally. Owing to the aggressive nature of the disease and intensity of treatment, survivors face long-term effects that impact on quality of life. Current models of follow-up post-treatment fail to address these complex issues. Given that 74% of patients with lymphoma cancer now survive 5 years beyond diagnosis and treatment, it is important to address this gap in care.

Aim:

To determine self-reported informational and practical needs, anxiety, depression, stress, coping and empowerment at baseline, 3 and 6 months.

Methods and analysis:

A pilot randomised controlled trial will …

Focus On The Journey, Not The Destination: Digital Games And Students With Disability, Susan Main, John O'Rourke, Julia Morris, Helen Dunjey

Research outputs 2014 to 2021

The way in which technologies support students with disability has been widely explored in recent times. Much of this research has focused on computer programs specifically designed to teach social and academic skills to students with disability. In the research reported in this paper we examined how students with disability could use technology designed for the general market. The impetus for the study was the principle of normalisation, which espouses that people with disability should have the opportunity to share in experiences of their same-aged peers. In previous research we demonstrated the benefits of using the commercially available hand-held games …

A Randomized Controlled Trial Of Very Early Rehabilitation In Speech After Stroke, Erin Godecke, Elizabeth Armstrong, Tapan Rai, Sandy Middleton, Natalie Ciccone, Anne Whitworth, Miranda Rose, Audrey Holland, Fiona Ellery, Graeme Hankey, Dominique Cadilhac, Julie Bernhardt

Research outputs 2014 to 2021

Rationale:

The efficacy of rehabilitation therapy for aphasia caused by stroke is uncertain.

Aims and hypothesis:

The Very Early Rehabilitation of Speech (VERSE) trial aims to determine if intensive prescribed aphasia therapy (VERSE) is more effective and cost saving than non-prescribed, intensive (usual care-plus) and non-intensive usual care (UC) therapy when started within 15 days of stroke onset and continued daily over four weeks. We hypothesize that aphasia therapy when started very early after stroke and delivered daily could enhance recovery of communication compared with UC.

Sample size estimates:

A total of 246 participants (82 per arm) will provide 80% …

A Review Of Current Neuromorphic Approaches For Vision, Auditory, And Olfactory Sensors, Anup Vanarse, Adam Osseiran, Alexander Rassau

Research outputs 2014 to 2021

Conventional vision, auditory, and olfactory sensors generate large volumes of redundant data and as a result tend to consume excessive power. To address these shortcomings, neuromorphic sensors have been developed. These sensors mimic the neuro-biological architecture of sensory organs using aVLSI (analog Very Large Scale Integration) and generate asynchronous spiking output that represents sensing information in ways that are similar to neural signals. This allows for much lower power consumption due to an ability to extract useful sensory information from sparse captured data. The foundation for research in neuromorphic sensors was laid more than two decades ago, but recent developments …

Rhizomatic Approaches To Screen-Based Music Notation, Lindsay R. Vickery

Research outputs 2014 to 2021

The rhizome concept explored by Deleuze and Guatarri has had an important influence on formal thinking in music and new media. This paper explores the development of rhizomatic musical scores that are arranged cartographically with nodal points allowing for alternate pathways to be traversed. The challenges of pre-digital exemplars of rhizomatic structure are discussed. It follows the development of concepts and technology used in the creation of five works by the author Ubahn c. 1985: the Rosenberg Variations [2012], The Last Years [2012], Sacrificial Zones [2014], detritus [2015] and trash vortex [2015]. this paper discusses the potential for the evolution …

Tectonic: A Networked, Generative And Interactive, Conducting Environment For Ipad, Lindsay R. Vickery Dr, Stuart James

Research outputs 2014 to 2021

This paper describes the concept, implementation and context of Tectonic: Rodinia for four realtime composer-conductoors and ensemble. In this work, an addition to the reqertoire of the Decibel Scoreplayer, iPads art networked together using the bonjour protocol to manage connectivity over the network. Unlike previous Scoreplayer works, Rodinia combines "conductor view" control interfaces, "performer view" notation interfaces and an "audience view" overview interface, separately identified by manual connection and yet mutually interactive. Notation is communicated to an ensemble via scores independently generated in realtime in each "performer view" and amalgamated schematically in the :audience view" interface. Interaction in the work …

Compliance, Palatability And Feasibility Of Paleolithic And Australian Guide To Healthy Eastin Diets In Healtthy Women: A 4-Week Dietary Intervention, Angela Genoni, Johnny Lo, Philippa Lyons-Wall, Amanda Devine

Research outputs 2014 to 2021

(1) Background/Objectives:

The Paleolithic diet has been receiving media coverage in Australia and claims to improve overall health. The diet removes grains and dairy, whilst encouraging consumption of fruits, vegetables, meat, eggs and nuts. Our aim was to compare the diet to the Australian Guide to Healthy Eating (AGHE) in terms of compliance, palatability and feasibility;

(2) Subjects/Methods:

39 healthy women (age 47 ± 13 years, BMI 27 ± 4 kg/m²) were randomised to an ad-libitum Paleolithic (n = 22) or AGHE diet (n = 17) for 4-weeks. A food checklist was completed daily, with mean discretionary consumption …

Examining Student Ict Ownership, Use And Preferences Towards Electronically Delivered Learning Resources In Nakhon Phanom University And Sakon Nakhon Rajabhat University, Yuwanuch Gulatee, Vijittra Vonganusith, Jeremy E. Pagram, Martin G. Cooper

Research outputs 2014 to 2021

The objectives of this research were 1) to find students’ ownership of technology devices, ownership, soft-ware facility, and preferences, 2) to find out what devices instructors use in the classroom, 3) to find out how the students use the online learning that the university provided for them, and 4) to examine students’ software skills. The questionnaire and the interview instruments were designed to clarify participants’ attitudes, and used a Likert scale. Surveys and qualitative research design were developed using Qualtrics software, which is an online research survey tool that can be used for a whole range of data gathering purposes …

A Multi-Point 2d Interface: Audio-Rate Signals For Controlling Complex Multi-Parametric Sound Synthesis, Stuart James

Research outputs 2014 to 2021

This paper documents a method of controlling complex sound synthesis processes such as granular synthesis, additive synthesis, timbre morphology, swarm-based spatialisation, spectral spatialisation, and timbre spatialisation via a multi-parametric 2D interface. This paper evaluates the use of audio-rate control signals for sound synthesis, and discussing approaches to de-interleaving, synchronization, and mapping. The paper also outlines a number of ways of extending the expressivity of such a control interface by coupling this with another 2D multi-parametric nodes interface and audio-rate 2D table lookup. The paper proceeds to review methods of navigating multi-parameter sets via interpolation and transformation. Some case studies are …

Disentangling The Complexity Of Groundwater Dependent Social-Ecological Systems, Olivier Barreteau, Yvan Caballero, Serena H. Hamilton, Anthony J. Jakeman, Jean-Daniel Rinaudo

Research outputs 2014 to 2021

Groundwater resources are part of larger social-ecological systems. In this chapter, we review the various dimensions of these complex systems in order to uncover the diversity of elements at stake in the evolution of an aquifer and the loci for possible actions to control its dynamics. Two case studies illustrate how the state of an aquifer is embedded in a web of biophysical and sociopolitical processes. We propose here a holistic view through an IGM-scape that describes the various possible pathways of evolution for a groundwater related social-ecological system. Then we describe the elements of this IGM-scape starting with physical …

Integrated Groundwater Management: An Overview Of Concepts And Challenges, Anthony J. Jakeman, Olivier Barreteau, Randall G. Hunt, Jean-Daniel Rinaudo, Andrew Ross, Muhammad Arshad, Serena H. Hamilton

Research outputs 2014 to 2021

Managing water is a grand challenge problem and has become one of humanity’s foremost priorities. Surface water resources are typically societally managed and relatively well understood; groundwater resources, however, are often hidden and more difficult to conceptualize. Replenishment rates of groundwater cannot match past and current rates of depletion in many parts of the world. In addition, declining quality of the remaining groundwater commonly cannot support all agricultural, industrial and urban demands and ecosystem functioning, especially in the developed world. In the developing world, it can fail to even meet essential human needs. The issue is: how do we manage …

Skill Mastery And The Formation Of Graduate Identity In Bachelor Graduates: Evidence From Australia, Denise Jackson

Research outputs 2014 to 2021

Mastery of certain generic skills and the successful formation of pre-professional identity are widely considered to influence graduate work-readiness and job attainment. Given their links with enhanced productivity, performance and innovation, skill development and graduate identity appear critical amidst ongoing global stagnation in advanced economies. This paper focuses on the success of higher education in developing generic skills and graduate identity using national data (n = 80,891) for 51 providers. It investigates the influence of certain demographics, study and degree characteristics on these important areas of undergraduate curricula. Furthermore, it gauges recent graduate perceptions on the importance of skill development …

Sparse Adaptive Local Machine Learning Algorithms For Sensing And Analytics, Jack Cannon

Maseeh Summer Undergraduate Research Experience

The goal of digital image processing is to capture, transmit, and display images as efficiently as possible. Such tasks are computationally intensive because an image is digitally represented by large amounts of data. It is possible to render an image by reconstructing it with a subset of the most relevant data. One such procedure used to accomplish this task is commonly referred to as sparse coding. For our purpose, we use images of handwritten digits that are presented to an artificial neural network. The network implements Rozell's locally competitive algorithm (LCA) to generate a sparse code. This sparse code is …

Life Of Christ, Steelman Library

Syllabus Repository

No abstract provided.

Biblical Hermeneutics, Kenneth J. Archer Dr.

Syllabus Repository

No abstract provided.