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Intensive, Regular Sampling And Removal Of Modest Numbers Of Fishes Shows No Measurable Impact On Fish Populations In Three Streams Of North Georgia, Steven L. Powers

Southeastern Fishes Council Proceedings

Recent publications and restrictions on collecting by state fish and game managers indicate a growing concern regarding the impact of field sampling on native fish populations. To evaluate the validity of these concerns, data from five life-history studies conducted in Cherokee County, Georgia were examined to test the hypothesis that regular sampling has a negative impact on fish populations. Number of individuals collected was divided by time collecting to calculate catch per unit effort (CPUE) as an indicator of relative abundance for each species. The collecting sequence (i.e. the number of times a species had previously been sampled) was regressed …

Sulfatase 2 Facilitates Lymphangiogenesis In Breast Cancer By Regulating Vegf-D., Chenfang Zhu, Xiaoliang Qi, Xin Zhou, Xin Nie, Yan Gu

Surgery Faculty Publications

In our previous studies, sulfatase 2 (Sulf2) was found to upregulate vascular endothelial growth factor-D (VEGF-D) expression in breast cancer. As VEGF-D plays an important role in lymphangiogenesis, we hypothesized that Sulf2 facilitates lymphangiogenesis in breast cancer by regulating VEGF-D. To evaluate the functions of Sulf2 on lymphangiogenesis in breast cancer, proliferation, apoptosis, cell cycle, cell mobility and tube-formation of lymphatic endothelial cells (LECs) were measured in vitro. Lymphangiogenesis in nude mouse ears and breast cancer xenografts were examined in vivo. Furthermore, the expression levels of related signaling pathway genes were screened and verified in LECs. We found that Sulf2 …

Ecological Crisis And The Re-Enchantment Of Nature In Jaime Huenún’S Reducciones., Ida Day

Modern Languages Faculty Research

Chilean poet Jaime Huenún’s Reducciones (Reductions; 2012) explores the social and environmental consequences of European colonization since the second half of the nineteenth century, when southern Chile received thousands of German immigrants as part of a state-sponsored colonization plan. Confronted with large stretches of impenetrable native forests, the colonists began a deforestation process in order to prepare the land for agriculture and livestock farming, which left a profound impact on the society, economy, and geography of the region. In less than a century, the region spanning La Araucanía to Chiloé lost at least three million hectares of native forests. The …

Spartan Daily, October 4, 2016, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2016

Volume 147, Issue 14

Tumor Vessel Normalization After Aerobic Exercise Enhances Chemotherapeutic Efficacy., Keri L Schadler, Nicholas J Thomas, Peter Galie, Dong Ha Bhang, Kerry C Roby, Prince Addai, Jacob E Till, Kathleen Sturgeon, Alexander Zaslavsky, Christopher S Chen, Sandra Ryeom

Henry M. Rowan College of Engineering Departmental Research

Targeted therapies aimed at tumor vasculature are utilized in combination with chemotherapy to improve drug delivery and efficacy after tumor vascular normalization. Tumor vessels are highly disorganized with disrupted blood flow impeding drug delivery to cancer cells. Although pharmacologic anti-angiogenic therapy can remodel and normalize tumor vessels, there is a limited window of efficacy and these drugs are associated with severe side effects necessitating alternatives for vascular normalization. Recently, moderate aerobic exercise has been shown to induce vascular normalization in mouse models. Here, we provide a mechanistic explanation for the tumor vascular normalization induced by exercise. Shear stress, the mechanical …

Ua12/2/1 College Heights Herald, Vol. 92, No. 12 [13], Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Ares, Nicole. Glowing Rose – Stephanie Campbell
• Collins, Emma. Search Committee Discusses Candidates
• Kast, Monica. WKU Could Receive Refund After Court Ruling – Budget
• Carlson, Kylie. International Delegates Fundraise for Refugees – International Student Diplomats
• King, Jennifer. Editorial Cartoon re: Register to Vote
• Democracy Deadline: Kentucky Voter Registration is Ending Soon
• Henderson, Andrew. Stars Foretell an Extremely Spooky October – Horoscopes
• Cole, Megan. Purple People – Alzheimer’s Research
• Martin, Madison. No Lost Generation Begins WKU Chapter
• Austin, Emma. Campus Organization Bridges Cultural Gaps – Bridges …

Attenuation Of Na/K-Atpase Mediated Oxidant Amplification With Pnaktide Ameliorates Experimental Uremic Cardiomyopathy, Jiang Liu, Jiang Tian, Muhammad Chaudhry, Nader G. Abraham, Joseph Shapiro

NYMC Faculty Publications

We have previously reported that the sodium potassium adenosine triphosphatase (Na/K-ATPase) can effect the amplification of reactive oxygen species. In this study, we examined whether attenuation of oxidant stress by antagonism of Na/K-ATPase oxidant amplification might ameliorate experimental uremic cardiomyopathy induced by partial nephrectomy (PNx). PNx induced the development of cardiac morphological and biochemical changes consistent with human uremic cardiomyopathy. Both inhibition of Na/K-ATPase oxidant amplification with pNaKtide and induction of heme oxygenase-1 (HO-1) with cobalt protoporphyrin (CoPP) markedly attenuated the development of phenotypical features of uremic cardiomyopathy. In a reversal study, administration of pNaKtide after the induction of uremic …

Attenuation Of Na/K-Atpase Mediated Oxidant Amplification With Pnaktide Ameliorates Experimental Uremic Cardiomyopathy, Jiang Liu, Jiang Tian, Muhammad Chaudhry, Kyle Maxwell, Yanling Yan, Xiaoliang Wang, Preeya T. Shah, Asad A. Khawaja, Rebecca Martin, Tylor J. Robinette, Adee El-Hamdani, Michael W. Dodrill, Komal Sodhi, Christopher A. Drummond, Steven T. Haller, David J. Keenedy, Nader G. Abraham, Zijian Xie, Joseph I. Shapiro Md

Biochemistry and Microbiology

We have previously reported that the sodium potassium adenosine triphosphatase (Na/K-ATPase) can effect the amplification of reactive oxygen species. In this study, we examined whether attenuation of oxidant stress by antagonism of Na/K-ATPase oxidant amplification might ameliorate experimental uremic cardiomyopathy induced by partial nephrectomy (PNx). PNx induced the development of cardiac morphological and biochemical changes consistent with human uremic cardiomyopathy. Both inhibition of Na/K-ATPase oxidant amplification with pNaKtide and induction of heme oxygenase-1 (HO-1) with cobalt protoporphyrin (CoPP) markedly attenuated the development of phenotypical features of uremic cardiomyopathy. In a reversal study, administration of pNaKtide after the induction of uremic …

Defining And Targeting Health Disparities In Chronic Obstructive Pulmonary Disease, Roy A. Pleasants, Isaretta L. Riley, David M. Mannino

Preventive Medicine and Environmental Health Faculty Publications

The global burden of chronic obstructive pulmonary disease (COPD) continues to grow in part due to better outcomes in other major diseases and in part because a substantial portion of the worldwide population continues to be exposed to inhalant toxins. However, a disproportionate burden of COPD occurs in people of low socioeconomic status (SES) due to differences in health behaviors, sociopolitical factors, and social and structural environmental exposures. Tobacco use, occupations with exposure to inhalant toxins, and indoor biomass fuel (BF) exposure are more common in low SES populations. Not only does SES affect the risk of developing COPD and …

Mitochondrial Dna Sequence And Lack Of Response To Anoxia In The Annual Killifish Austrofundulus Limnaeus, Josiah Tad Wagner, Florisela Herrejon Chavez, Jason E. Podrabsky

Center for Life in Extreme Environments Publications

The annual killifish Austrofundulus limnaeus inhabits ephemeral ponds in regions of Venezuela, South America. Permanent populations of A. limnaeus are maintained by production of stress-tolerant embryos that are able to persist in the desiccated sediment. Previous work has demonstrated that A. limnaeus have a remarkable ability to tolerate extended periods of anoxia and desiccating conditions. After considering temperature, A. limnaeus embryos have the highest known tolerance to anoxia when compared to any other vertebrate yet studied. Oxygen is completely essential for the process of oxidative phosphorylation by mitochondria, the intracellular organelle responsible for the majority of adenosine triphosphate production. Thus, …

First Direct Evidence Of Long-Distance Seasonal Movements And Hibernation In A Migratory Bat, Theodore J. Weller, Kevin T. Castle, Felix Liechti

KIP Articles

Understanding of migration in small bats has been constrained by limitations of techniques that were labor-intensive, provided coarse levels of resolution, or were limited to population-level inferences. Knowledge of movements and behaviors of individual bats have been unknowable because of limitations in size of tracking devices and methods to attach them for long periods. We used sutures to attach miniature global positioning system (GPS) tags and data loggers that recorded light levels, activity, and temperature to male hoary bats (Lasiurus cinereus). Results from recovered GPS tags illustrated profound differences among movement patterns by individuals, including one that completed a >1000 …

Beryllium Nitrate Inhibits Fibroblast Migration To Disrupt Epimorphic Regeneration, Adam B. Cook, Ashley W. Seifert

Biology Faculty Publications

Epimorphic regeneration proceeds with or without formation of a blastema, as observed for the limb and skin, respectively. Inhibition of epimorphic regeneration provides a means to interrogate the cellular and molecular mechanisms that regulate it. In this study, we show that exposing amputated limbs to beryllium nitrate disrupts blastema formation and causes severe patterning defects in limb regeneration. In contrast, exposing full-thickness skin wounds to beryllium only causes a delay in skin regeneration. By transplanting full-thickness skin from ubiquitous GFP-expressing axolotls to wild-type hosts, we demonstrate that beryllium inhibits fibroblast migration during limb and skin regeneration in vivo. Moreover, …

Eavesdropping On The Ocean, Robbin Ray

UNH Today Archive

No abstract provided.

Effective Treatment Of Esophageal Adenocarcinoma Using Triciribine And Related Compounds, Jing Q. Cheng

USF Patents

The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat esophogeal adenocarcinoma by one or a combination of (i) administering triciribine only to patients which according to a diagnostic test described below, exhibit enhanced sensitivity to the drug; (ii) use of a described dosage level that minimizes the toxicity of the drug but yet still exhibits efficacy; or (iii) use of a described dosage regimen that minimizes the toxicity of the drug.

Compositions And Methods For Adipocyte Modulation, Niketa A. Patel, Rekha S. Patel, Kirpal S. Bisht

USF Patents

Modified stilbenoids and formulations thereof are provided. The modified stilbenoids can include one or more amino or amino-alkyl substituents. The formulation can be for the treatment or prevention of obesity and the modified stilbenoid present in an effective amount to alleviate or prevent the onset of one or more symptoms of obesity. Methods of making the modified stilbenoids and formulations thereof are provided. Methods are provided for treating a subject with a modified stilbenoid in an effective amount to alleviate or prevent one or more symptoms associated with diabetes, cardiovascular disease, high blood pressure, deep vein thrombosis, osteoarthritis, obstructive sleep …

The Sun Star Vol 36 No 6 ( October 4th, 2016), N/A N/A

Sun Star

No abstract provided.

Applied Photoproperties Of Phenylene Ethynylenes, Patrick L. Donabedian

Nanoscience and Microsystems ETDs

Light-absorbing molecules can be used as powerful tools to perturb and understand biological systems by fluorescence, sensitization, or photochemical reactions. A thorough understanding of the delivery of dyes to specific biochemical targets and the processes that control the fate of excited-state energy is needed to engineer useful technology out of organic photochemistry. This thesis presents four projects investigating different aspects of pathogen destruction and biochemical sensing in a variety of systems, using the properties of p-phenylene ethynylenes (PEs), an especially flexible and well-studied class of conjugated molecules. Of particular relevance, some PEs are found to be effective dyes for amyloid …

Fhf2 Gene Deletion Causes Temperature-Sensitive Cardiac Conduction Failure, David S. Park, Akshay Shekhar, Christopher Marra, Xianming Lin, Carolina Vasquez, Sergio Solinas, Kevin Kelley, Gregory Morley, Mitchell Goldfarb, Glenn I. Fishman

Publications and Research

Fever is a highly conserved systemic response to infection dating back over 600 million years. Although conferring a survival benefit, fever can negatively impact the function of excitable tissues, such as the heart, producing cardiac arrhythmias. Here we show that mice lacking fibroblast growth factor homologous factor 2 (FHF2) have normal cardiac rhythm at baseline, but increasing core body temperature by as little as 3 C causes coved-type STelevations and progressive conduction failure that is fully reversible upon return to normothermia. FHF2-deficient cardiomyocytes generate action potentials upon current injection at 25 C but are unexcitable at 40 C. The absence …

Deferoxamine Preventable Hepatocellular Damage, Following Hemorrhagic Shock, Charles F. Babbs, David W. Griffin

Weldon School of Biomedical Engineering Faculty Working Papers

To examine the role of iron in mediating hepatocellular damage during reperfusion after hemorrhagic shock, we studied five groups of n=4 or 5 dogs, bled to reduce mean arterial pressure to 35 mmHg (± 5mrnHg) for three hours and subsequently treated 20 minutes prior to reinfusion of shed blood with either 0.9% saline, 5 ml/kg; deferoxamine, 50 μg/kg in 0.9% saline; 6% pentastarch solution, 5 ml/kg; deferoxamine covalently bound to 6% pentastarch, 50 μg/kg; or iron loaded deferoxamine in 0.9% saline. Saturation of iron binding capacity increased during hemorrhagic shock and remained high in all but the def eroxamine pentastarch …

Elliott V. Young Respondent's Brief Dckt. 44068

Not Reported

No abstract provided.

The Bg News October 4, 2016, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. October 4, 2016. Volume 96-Issue 14.

The Prospector, October 4, 2016, Utep Student Publications

The Prospector

Headline: "I Could Care Less If My Hair Makes You Uncomfortable": UTEP's Black Student Union Stands With Natural Hair Movement

The George-Anne, Georgia Southern University

The George-Anne

• Opinions
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Brief Amici Curiae Of Professors Of History, Political Science, And Law In Support Of Respondent, Kristin Collins, Catherine E. Stetson, Jessica K. Jacobs

Faculty Scholarship

Sex-based laws premised on archaic presumptions about the proper roles of men and women run afoul of established constitutional principles, especially when they interfere with the parent-child relationship. Amici write to explain the history of the federal government’s use of sex-based classifications in the regulation of citizenship. In its regulation of intergenerational and interspousal citizenship transmission, the federal government has perpetuated outdated gender-based norms concerning proper parental roles, even when those norms have been rejected in other legal and social contexts. In addition, the laws governing derivative citizenship have significantly encumbered the ability of American fathers to transmit citizenship to …

Access To The Safe Harbor: Bioterrorism, Influenza, And The Supreme Court's Interpretation Of The Research Exemption From Patent Infringement, Michael J. Brignati

Journal of Intellectual Property Law

No abstract provided.

Intellectual Property And The Protection Of Industrial Design: Are Sui Generis Protection Measures The Answer To Vocal Opponents And A Reluctant Congress?, Regan E. Keebaugh

Journal of Intellectual Property Law

No abstract provided.

Machinima And Copyright Law, Matthew Brett Freedman

Journal of Intellectual Property Law

No abstract provided.

Is The Monopoly Theory Of Trademarks Robust Or A Bust?, Harold R. Weinberg

Journal of Intellectual Property Law

The monopoly theory of trademarks would antitrustize trademark law by incorporating antitrust legal precedent, economics, policies, reasoning, and terminology. The theory is comprised of six interrelated postulates contained in trademark law and scholarship. The postulates are (1) trademarks are monopolies; (2) trademark monopolies are like illegal antitrust monopolies because both harm competition; (3) trademark law is like antitrust law because both value competition; (4) trademark law is like antitrust law because both apply economic methodology to product markets; (5) an antitrust lens can help one understand trademarks and trademark law; and (6) an antitrust lens can help one decide whether …

A Positive Externalities Approach To Copyright Law: Theory And Application, Jeffrey L. Harrison

Journal of Intellectual Property Law

This Article has two goals. The first is to explain in some detail what copyright law might look like if it reflected economic reasoning. The second is to put to the test the question of whether copyright law is as far out of sync with economic guidelines as cases ranging from White-Smith Music to Eldred suggest. Although this introduction has stressed the economic irrationality of copyright law, could it actually be that within copyright decisions there is an implicit economic sensibility?

The Biotechnology Process Patent Act Of 1995: Providing Unresolved And Unrecognized Dilemmas In U.S. Patent Law, Becca Alley

Journal of Intellectual Property Law

No abstract provided.