Digital Commons Network^™

Constitutively Activated Pi3k Accelerates Tumor Initiation And Modifies Histopathology Of Breast Cancer, M. R. Sheen, J. D. Marotti, M. J. Allegrezza, M. Rutkowski, J. R. Conejo-Garcia, S. Fiering

Dartmouth Scholarship

The gene encoding phosphatidylinositol 3-kinase catalytic subunit α-isoform (PIK3CA, p110α) is frequently activated by mutation in human cancers. Based on detection in some breast cancer precursors, PIK3CA mutations have been proposed to have a role in tumor initiation. To investigate this hypothesis, we generated a novel mouse model with a Cre-recombinase regulated allele of p110α (myristoylated-p110α, myr-p110α) along with p53fl/fl deletion and KrasG12D also regulated by Cre-recombinase. After instillation of adenovirus-expressing Cre-recombinase into mammary ducts, we found that myr-p110α accelerated breast tumor initiation in a copy number-dependent manner. Breast tumors induced by p53fl/fl;KrasG12D with no or one copy of myr-p110α …

"Hul Topol" - Fall Of The Moon A Narrative Of Etiologies From The Bunaq Of Lamaknen, Antoinette Schapper

Wacana, Journal of the Humanities of Indonesia

This article makes a contribution to the documentation of the genre of oral literature known as zapal amongst the Bunaq, a Papuan-speaking group of central Timor. I present an annotated and translated version of the elaborate zapal entitled Hul Topol or Fall of the Moon. Hul Topol is a lengthy, multi-event story which gives etiologies spanning the realms of subsistence, cultural practice and natural order including animal behaviour and appearance.

Dairi Storytelling And Stories In The Batak Reader Of Herman Neubronner Van Der Tuuk, Clara Brakel Papenhuyzen

Wacana, Journal of the Humanities of Indonesia

In this article I first discuss how texts of Dairi stories collected in the nineteenth century by Herman Neubronner van der Tuuk relate to storytelling, and question whether the development of written versions of stories necessarily endangers the practice of storytelling. Then I investigate how written versions of Dairi stories in Van der Tuuk's Batak Reader relate to each other and to the printed text, based on texts in manuscripts collected by Van der Tuuk. In conclusion I discuss the possible aim of Van der Tuuk's Batak Reader, focussing on the Dairi section, which has not been dealt with in …

Student Life E-Newsletter October 31, 2016, Seattle University School Of Law Student Life

Student Life E-Newsletters

No abstract provided.

Flat Puppets On An Empty Screen, Stories In The Round; Imagining Space In "Wayang Kulit" And The Worlds Beyond, Bernard Arps

Wacana, Journal of the Humanities of Indonesia

The puppets are flat, the screen against which they are placed and moved is white and devoid of scenery. In what kinds of space do the stories of the classical shadow-play of Java, Bali, Lombok, and the Malay world unfold despite this double flatness? How do performers use not only puppets and screen but also music and language to bring space into being? What must spectators know and do to make sense of these storytelling techniques? As a contribution to the narratological study of the multimodal making of storyworlds, I demonstrate that wayang kulit caters for different degrees of interpretive …

The Art Of Storytelling In Old Javanese Prose As Illustrated By The Story Of Ekalawya, Willem Van Der Molen

Wacana, Journal of the Humanities of Indonesia

Scholarly attention for Old Javanese literature so far has mainly focused on poetry. The apparently simple nature of narrative prose texts, while making them excellent sources for linguistic and lexicographic research, at the same time denies them any literary value. In this article an impression is given of the art of storytelling in one Old Javanese prose story, taken from the Adiparwa of around A.D. 1000. Quite unexpectedly, a sophisticated tradition unfolds in which a rich variety of devices enables the storyteller to create a meaningful world of words.

Tatlong Kuwento Ni Lola Basyang. Ballet Manila. Aliw Theater, Manila. August 21, 2015. Choreography By Osias Barroso, Lisa Macuja-Elizalde, And Tony Fabella. Based On Stories Written By Severino Reyes., Maria Gabriela P. Martin

Perspectives in the Arts and Humanities Asia

Excerpt: Since its establishment in 1995, Ballet Manila has distinguished itself as a company by adopting local and popular elements in Philippine culture. Its founder and artistic director Lisa Macuja, in fact, has been touted by local media as the “ballerina ng bayan” in recognition of her bid to make ballet more accessible to a wider mass audience. The company’s restaging of Tatlong Kuwento ni Lola Basyang, which opened its twentieth season, was a valiant effort at popularizing ballet. The production adapts three children’s books, written by Christine Bellen and illustrated by Frances Alcaraz, that retell three Lola Basyang stories.

Maria Christine Muyco And Panay Bukidnon Represented By Lucia Caballero. Sibod: Ideology And Expressivity In Binanog Dance, Music, And Folkways Of The Panay Bukidnon. Quezon City: Ateneo De Manila University Press. 2016. 243 Pages., Genevieve L. Asenjo

Perspectives in the Arts and Humanities Asia

Excerpt: Among the Panay Bukidnon, the word sibod means “an experience of flow, . . . a state of having achieved mastery in different levels of structural and creative interplay” (xii). It is simultaneously noun, adjective, and most especially verb. In Sibod: Ideology and Expressivity in Binanog Dance, Music, and Folkways of the Panay Bukidnon, Maria Christine Muyco, an Ilonggo music composer and ethnomusicologist at the University of the Philippines (UP) Diliman, offers us a framework for understanding the performing arts of a community of epic chanters and storytellers, musicians and dancers of binanog (hawk-eagle dance), embroiderers, and farmers living …

Table Of Contents

Professional Agricultural Workers Journal

No abstract provided.

Sustainable Farm Practice: Study Of Total And Soluble Phosphorus In A Poultry Farm Equipped With Heavy Use Area Protection Pads, Dover, Delaware, Gulnihal Ozbay, Raju Khatiwada, Lathadevi K. Chintapenta, Eunice F. Handy, Stacy L. Smith

Professional Agricultural Workers Journal

Poultry litter contains high concentrations of water-soluble phosphorus and is readily transported in the farm run-off. This research aims to study the efficiency of heavy use area protection (HUAP) pads in decreasing litter spillage and phosphorous run-off at a Delaware poultry facility. Soil and water samples were analyzed for pH, total phosphorous, orthophosphate, and Mehlich III phosphorous throughout 2012. It has been hypothesized that the efficiency of HUAP pads would be reduced over time. Mehlich III phosphorus ranged from 22.82-200 mg/kg at site I, and 48.17 – 1179.6 mg/kg at site II, which were greater than the optimal soil concentrations. …

National Food Safety: Training, Education, Extension, Outreach, And Technical Assistance Program And The National Curriculum Stand For Food Protection Professionals, Gerald Wojtala

Professional Agricultural Workers Journal

No abstract provided.

Grazing With Goats Changed The Woodland Plant-Species Composition During Summer, Rishi Khatri, Uma Karki, Jerry Bettis, Yubaraj Karki

Professional Agricultural Workers Journal

Abstract

Woodland grazing is a common practice in the Southeast; however, information is limited on its effects on the woodland plant-species composition. The study objective was to determine the effect of summer grazing on woodland plant-species composition. Before- and after-grazing observations were taken at the ground, mid, and high levels in three plots (1-acre each) along the pre-established transects. Kiko wethers (29, 6-8 months old, 26.8±0.67 kg body weight) were allowed to graze the plots after before-grazing observations were taken. After-grazing observations were taken immediately after the goats were moved out from the plots. Grazing showed a significant effect on …

Pyk2 Activates The Nlrp3 Inflammasome By Directly Phosphorylating Asc And Contributes To Inflammasome-Dependent Peritonitis, I-Che Chung, Chun-Nan Ouyang, Sheng-Ning Yuan, Hsin-Pai P. Li, Jeng-Ting Chen, Hui-Ru Shieh, Yu-Jen Chen, David M. Ojcius, Ching-Liang Chu, Jau-Song Yu, Yu-Sun Chang, Lih-Chyang Chen

All Dugoni School of Dentistry Faculty Articles

The inflammasome adaptor protein, ASC, contributes to both innate immune responses and inflammatory diseases via self-oligomerization, which leads to the activation of the protease, caspase-1. Here, we report that the cytosolic tyrosine kinases, FAK and Pyk2, are differentially involved in NLRP3 and AIM2 inflammasome activation. The inhibition of FAK and Pyk2 with RNA interference or chemical inhibitors dramatically abolished ASC oligomerization, caspase-1 activation, and IL-1β secretion in response to NLRP3 or AIM2 stimulation. Pyk2 is phosphorylated by the kinase Syk and relocalizes to the ASC specks upon NLRP3 inflammasome activation. Pyk2, but not FAK, could directly phosphorylate ASC at Tyr146, …

Nutrition And Dietetic Students' Vitamin And Mineral Knowledge And Concurrent Learning And Retention Strategies, Katie Nicole Brown, Jenna Ellis, Dana Ogan, Heidi Wengreen

Nutrition, Dietetics, and Food Sciences Faculty Publications

Background: The functions, food sources, deficiency symptoms, and toxicity symptoms are important for dietetic professionals to know and apply to community, food service, and clinical settings. Purpose: To assess nutrition and dietetic students' knowledge of vitamins and minerals and identify students' strategies for learning and retaining vitamin and mineral information. Methodology: Students from three universities in the western United States were invited to participate in cross-sectional study. Participants completed a brief questionnaire that included multiple choice and short answer questions to assess their knowledge of a representative list of 8 vitamins and minerals. The questionnaire also included free-response questions about …

Human Rights, Religious Freedom, And Peace, David Little

BYU Law Review

No abstract provided.

The Rider (2016-10-31), Jesus Sanchez

The Rider Archives

Vol.2 No.10

A Comprehensive Review Of The 2016 Asha Code Of Ethics, Robin L. Edge Ph.D., Ccc-Slp, Bess Sirmon-Taylor Ph.D., Ccc-Slp, Raul F. Prezas Ph.D., Ccc-Slp

Journal of Human Services: Training, Research, and Practice

The American Speech-Language-Hearing Association (ASHA) initially implemented a Code of Ethics in 1952, and has periodically revisited the content of the document with revisions to reflect the expanding scope of practice within speech-language pathology and audiology and to clarify certain concepts. Code revision is a cyclical mandated task of the ASHA Board of Ethics conducted to assure accuracy, currency, and completeness of this most important document (Solomon-Rice & O’Rourke, 2016). The current version of the Code of Ethics (2016) was modified from the previous version (2010r), with an updated preamble, definitions of related vocabulary, and re-organized language in the principles. …

Women In The Shadows : Gender, Puppets, And The Power Of Tradition In Bali, Jennifer Goodlander

Ohio University Press Open Access Books

Wayang kulit, or shadow puppetry, connects a mythic past to the present through public ritual performance and is one of most important performance traditions in Bali. The dalang, or puppeteer, is revered in Balinese society as a teacher and spiritual leader. Recently, women have begun to study and perform in this traditionally male role, an innovation that has triggered resistance and controversy.
In Women in the Shadows, Jennifer Goodlander draws on her own experience training as a dalang as well as interviews with early women dalang and leading artists to upend the usual assessments of such gender role shifts. She …

Moens'written Transmission Of Dalang Lore, Victoria M. Clara Van Groenendael

Wacana, Journal of the Humanities of Indonesia

Much of the storytelling in Java is the profession of the puppeteers (dalang; also spelled dhalang) who perform and direct shadow theatre plays (wayang). They improvise their stories in the context which their performance requires. Unless commissioned to do so by a patron, it is very unusual for a dalang to sit down and actually write out a story (lakon). In the early decades of the twentieth century in the area of Yogyakarta, a kind of storytelling mini-industry arose at the instigation of some western scholarly patrons and laymen interested in Javanese popular culture. One such patron was Ir. J.L. …

The Pig Story "Tiboi Sakkoko"; Storytelling Of Kinship, Memories Of The Past, And Rights To Plots Of Ancestral Land In Mentawai, Juniator Tulius

Wacana, Journal of the Humanities of Indonesia

This paper examines some significant elements of the pig story (tiboi sakkoko). This tale contains crucial information about the collective identity, ancestors and historical events affecting particular Mentawai kin-groups. As families do not preserve their culture and traditions in written form, storytellers of kin-groups have narrated the pig story from generation to generation so as to preserve it carefully. In the course of time, storytellers establish particular ways of telling their stories so as to remember the content and plot of the stories easily. Through the pig story, members of kin groups also recollect their ancestral place of origin and …

Some Notes On The "Pantun" Storytelling Of The Baduy Minority Group Its Written And Audiovisual Documentation, Wim Van Zanten

Wacana, Journal of the Humanities of Indonesia

Baduy pantun stories are part of the larger Sundanese oral tradition of pantun storytelling in west Java. The stories recount the deeds of the nobility of such old Sundanese kingdoms as Pajajaran and Galuh. Although the Baduy still recite the pantun stories in their rituals, in the larger cities to the east of the Baduy village Kan k s pantun recitation almost disappeared. On the basis of short periods of fieldwork in and around Kan k s village between 1976 and 2014, in this essay I shall discuss Baduy pantun storytelling. I shall summarize earlier major publications and analyse some …

Why Do They (Still) Sing Stories? Singing Narratives In Tanjung Bunga (Eastern Flores, Lamaholot, Indonesia), Dana Rappoport

Wacana, Journal of the Humanities of Indonesia

In eastern Flores, on the Tanjung Bunga peninsula (among Western Lamaholot speakers), several times a year, ritual narratives (opak) are performed on a square dancing area, where all the clans of the same ceremonial land meet. Three types of narrative are sung, according to three kinds of rituals. The article explains the context, content and performance details of these stories, performed all night long. Why do the various clans continue to sing all these narrative? What values do these long poems have for people who sing them? Until now, studies on this subject have been remarkably few, and not even …

Images Of God In Toba Batak Storytelling, Johann Angerler

Wacana, Journal of the Humanities of Indonesia

This paper examines the ways in which God the Creator, the High God, is described in Toba Batak folk-tales. The sources for this investigation are stories recorded in pre-colonial (around 1850), colonial and post-colonial times (up to 2014). In different stories the High God can appear under various names, forms and gender, and resides in various places never inhabited by humans. Unlike a Deus otiosus, the Toba Batak High God is not "inactive" after creation, but continues to be involved in the life of mankind through local or supra-local manifestations. Although he rules the realm of death, he is nevertheless …

Contribution Of Epithelial Hypoxia Signaling To Pulmonary Fibrosis: Role Of Fak1 And Galectin-1 As Driver Molecules, Jaymin J. Kathiriya

USF Tampa Graduate Theses and Dissertations

Idiopathic Pulmonary Fibrosis (IPF) is a deadly disease of unknown origin, which causes 80,000 deaths every year in the US and Europe combined. Unknown etiology and late diagnosis, combined with limited treatment options, contribute to a dismal survival rate of 3-5 years post diagnosis. Although molecular mechanisms underlying IPF pathogenesis and progression have been studied for over two decades, lack of in vivo models that recapitulate chronic, progressive, and irreversible nature of IPF have contributed to limited therapeutic success in clinical trials. Currently, only two drugs, Pirfenidone and Nintedanib, are approved for IPF treatment in the US, with their efficacy …

Regulation Of Microvascular Flow And Metabolism: An Overview, Michelle A. Keske, Renee M. Dwyer, Ryan D. Russell, Sarah J. Blackwood, Aascha A. Brown, Donghua Hu, Dino Premilovac, Stephen M. Richards, Stephen Rattigan

Health & Human Performance Faculty Publications

Skeletal muscle is an important site for insulin to regulate blood glucose levels. It is estimated that skeletal muscle is responsible for ~80% of insulin-mediated glucose disposal in the post-prandial period. The classical action of insulin to increase muscle glucose uptake involves insulin binding to insulin receptors on myocytes to stimulate glucose transporter 4 (GLUT 4) translocation to the cell surface membrane, enhancing glucose uptake. However, an additional role of insulin that is often under-appreciated is its action to increase muscle perfusion thereby improving insulin and glucose delivery to myocytes. Either of these responses (myocyte and/or vascular) may be impaired …

Professor Shelley Hamill To Be Honored Nov. 12 With State Award, Winthrop University

Winthrop News 2016

• It was noted that Professor Shelley Hamill has served the alliance in multiple leadership roles, including as president and member of several committees.
• At Winthrop, she teaches various courses in health and health education at the graduate and undergraduate level in the Department of Physical Education, Sport and Human Performance. Her areas of specialty include pedagogy and human sexuality.

Haploinsufficiency Of The Myc Regulator Mtbp Extends Survival And Delays Tumor Development In Aging Mice., Brian C. Grieb, Kelli Boyd, Ramkrishna Mitra, Christine M. Eischen

Department of Cancer Biology Faculty Papers

Alterations of specific genes can modulate aging. Myc, a transcription factor that regulates the expression of many genes involved in critical cellular functions was shown to have a role in controlling longevity. Decreased expression of Myc inhibited many of the deleterious effects of aging and increased lifespan in mice. Without altering Myc expression, reduced levels of Mtbp, a recently identified regulator of Myc, limit Myc transcriptional activity and proliferation, while increased levels promote Myc-mediated effects. To determine the contribution of Mtbp to the effects of Myc on aging, we studied a large cohort of Mtbp heterozygous mice and littermate matched …

Developing Audio-Visual Media Of Fables And Folktales For English Speaking Activity In Junior High School Classroom, Zahrah Zakiya Ahda

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

This study aims at developing a simple audio-visual media of folktales and fables as media for speaking activity in Junior High School. The research adopts R&D design. The media is in the form of Flash media. There are two self-made digital stories and two narrated stories from folktales and fables in Asia. Each story is followed up by questions. Three classes were used as the participant in the tryout. For instruments, a checklist was used by the experts and English teachers; another checklist was used by the students. The result showed that the product is well accepted and liked by …

The Service Learning Ipe Model: Implementation And Results From Qualitative Studies, Daniel Estrada, Phd, Mba, Mhs, Amara Estrada, Dvm, Erik Black, Phd, Nichole Stetten, Mph, Linda Behar-Horenstein, Phd, Amy Blue, Phd

JCIPE Conference

This workshop will discuss the challenges, opportunities and lessons learned around the implementation and execution of the interprofessional education (IPE) program at the University of Florida. Qualitative research will be presented identifying themes from participating health profession programs confirming the important value of IPE initiatives in health profession education.

The continued evolution from acute episodic care to chronic long term care in the United States is forcing health care providers to work in a more collaborative manner. The IOM has called for changes in health profession education, specifically highlighting the need of IPE in health profession curriculum. IPE programs in …

Mimycx: A Tool For Interprofessional Education, Ruth E. Nemire, Pharmd,Edd, John Damici, Rahul Noria, Pharmd

JCIPE Conference

Objectives:

Evaluate the tool Mimycx for use in advancing interprofessional education and practice.

Analyze the kind of learning that can be offered through the use of online interactive tools.

Workshop:

This workshop provides time for attendees to interact with the developers of Mimycx, an interactive educational tool, for interprofessional education. In order to adopt new technologies faculty need to have opportunities for hands on experience. Mimycx is a massive multiplayer online tool for students to interact with one another in environments that promote team work, creative thinking and problem solving. The interactions, and activity of the learner are recorded for …