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2015

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Preference On Medication Therapy Management (Mtm) Service: Results From Discrete Choice Experiment, Sutthawan Chancheochai, Rungpetch Sakulbumrungsil, Surachat Ngorsurachet Jan 2015

Preference On Medication Therapy Management (Mtm) Service: Results From Discrete Choice Experiment, Sutthawan Chancheochai, Rungpetch Sakulbumrungsil, Surachat Ngorsurachet

The Thai Journal of Pharmaceutical Sciences

Objectives: To assess preference and estimate willingness to pay (WTP) for medication therapy management (MTM) service. Method: A discrete choice experiment (DCE) was conducted in general population. The five relevant MTM service attributes (service sett...

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Development And Validation Of A Stability-Indicating Hplc Method For Determination Of Clorazepate Dipotassium And Its Main Impurities In Bulk Drug And Capsules, Jankana Burana-Osot, Chanokporn Sukonpan, Sooksri Ungboriboonpisal Jan 2015

Development And Validation Of A Stability-Indicating Hplc Method For Determination Of Clorazepate Dipotassium And Its Main Impurities In Bulk Drug And Capsules, Jankana Burana-Osot, Chanokporn Sukonpan, Sooksri Ungboriboonpisal

The Thai Journal of Pharmaceutical Sciences

A simple isocratic stability-indicating HPLC method was developed and validated for the simultaneous determination of clorazepate dipotassium in the presence of its main impurities; nordiazepam and 2-amino-5- chlorobenzophenone, in bulk drug and capsul...

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Cocrystallization Of Artemisinin And Amodiaquine Hydrochloride, Wiriyaporn Sirikun, Jittima Chatchawalsaisin, Narueporn Sutanthavibul Jan 2015

Cocrystallization Of Artemisinin And Amodiaquine Hydrochloride, Wiriyaporn Sirikun, Jittima Chatchawalsaisin, Narueporn Sutanthavibul

The Thai Journal of Pharmaceutical Sciences

Artemisinin (ART) and amodiaquinedihydrochloride dihydrate (AQD) was selected as model host and guest molecules in the study. Cocrystallization of ART and AQD at mole ratio of 1:1 by temperature change technique using ethanol, new structure was found, ...

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Fp-15-05 Median Age At First Marriage, 2013, Krista K. Payne Jan 2015

Fp-15-05 Median Age At First Marriage, 2013, Krista K. Payne

National Center for Family and Marriage Research Family Profiles

No abstract provided.

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Fp-15-15 Assortative Mating: Educational Homogamy In U.S. Marriages, 1964-2014, Esther Lamidi, Susan L. Brown, Wendy D. Manning Jan 2015

Fp-15-15 Assortative Mating: Educational Homogamy In U.S. Marriages, 1964-2014, Esther Lamidi, Susan L. Brown, Wendy D. Manning

National Center for Family and Marriage Research Family Profiles

No abstract provided.

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Subdural Hematoma As A Consequence Of Epidural Anesthesia., Tracy M Bishop Do, Kareem S. Elsayed Ms, Kathleen E. Kane Md Jan 2015

Subdural Hematoma As A Consequence Of Epidural Anesthesia., Tracy M Bishop Do, Kareem S. Elsayed Ms, Kathleen E. Kane Md

Department of Emergency Medicine

Regional spinal and epidural anesthesia are used commonly in operative procedures. While the most frequent complication, postdural puncture headache (PDPH), is a clinically diagnosed positional headache that is usually self-limited, subdural hemorrhage (SDH) is a potentially fatal complication that cannot be missed. We report a case of an otherwise healthy female who presented with persistent positional headache and was ultimately found to have a large subdural hematoma with midline shift requiring surgical evacuation.

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The Higher Worlds Meet The Lower Criticism New Scholarship On Rudolf Steiner, Peter Staudenmaier Jan 2015

The Higher Worlds Meet The Lower Criticism New Scholarship On Rudolf Steiner, Peter Staudenmaier

History Faculty Research and Publications

No abstract provided.

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Drive-By Bridge Damage Inspection, Ahmed Ali Elhattab Jan 2015

Drive-By Bridge Damage Inspection, Ahmed Ali Elhattab

All ETDs from UAB

Bridge structures are subjected to continuous degradation due to environmental effects and increase in traffic loading. Bridge monitoring is a key element of any maintenance strategy as it can provide early signs of structural deterioration. In recent years, the demand towards sensor-based bridge monitoring in lieu of visual inspection, has increased. However, sensor-based monitoring is costly and requires significant maintenance. Recent studies on bridge damage monitoring have focused on the instrumentation of a passing vehicle instead of the bridge. This approach is referred to ‘drive-by’ bridge inspection (Kim and Kawatani, 2009). Using this approach, the bridge itself is not instrumented, …

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Elliptic Equations And Systems With Nonlinear Boundary Conditions, Alzaki Mohmoud Muhammed Fadlallah Jan 2015

Elliptic Equations And Systems With Nonlinear Boundary Conditions, Alzaki Mohmoud Muhammed Fadlallah

All ETDs from UAB

This dissertation presents some results on the solvability of second order elliptic equations with nonlinear boundary conditions at resonance, in which the nonlinear boundary conditions perturbation is not necessarily required to satisfy Landesman- Lazer conditions or the monotonicity assumption. The nonlinearity may be unbounded. The nonlinearity interacts in some sense with the Steklov spectrum. The proofs are based on a priori estimates for possible solutions to a homotopy on suitable trace spaces and topological degree arguments. We will also study solvability of nonlinear second-order elliptic systems of partial differential equations with nonlinear boundary conditions. We study the generalized Steklov-Robin eigensystem …

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Phase Transitions Under Nanoconfining Conditions, Reza Farasat Jan 2015

Phase Transitions Under Nanoconfining Conditions, Reza Farasat

All ETDs from UAB

The objective of this dissertation was to study the effects of nanoconfinement on the thermodynamic and kinetic parameters of phase transitions in selected compounds. The compounds were loaded into silica gel nanopores and filled them partially. A model was developed for estimating the fullness of the nanopores as well as the height of the compound layer deposited on the pore walls. A study of the phase transition in NH4Cl confined to the native silica gel nanopores revealed that the heat of transition increases with the increasing the layer height. Also the transition temperature measured on heating and cooling respectively increases …

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The Effect Of Thioredoxin-Interacting Protein Induced Microrna-200 Family Members On Pancreatic Beta Cells, Stephen Filios Jan 2015

The Effect Of Thioredoxin-Interacting Protein Induced Microrna-200 Family Members On Pancreatic Beta Cells, Stephen Filios

All ETDs from UAB

Pancreatic beta cells secrete insulin to maintain normal blood glucose levels and allow cells of the body to use glucose. However, in diabetes, there is beta cell dysfunction and pancreatic beta cells undergo programmed cell death leading to inadequate insulin production and secretion. Thioredoxin-Interacting Protein (TXNIP) is a ubiquitously expressed protein, 46 kDa in size, which is an arrestin protein family member. Unique to this member of the arrestin family, however, is its ability to bind to, and reduce, thioredoxin. The TXNIP gene is increased in pancreatic islets more than any other gene in response to high levels of glucose. …

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Exercise Adherence Among Pregnant Women: The Roles Of Socioeconomic Status, Attitudes Towards Prenatal Exercise, And Social Support, Lee Anne Flagg Jan 2015

Exercise Adherence Among Pregnant Women: The Roles Of Socioeconomic Status, Attitudes Towards Prenatal Exercise, And Social Support, Lee Anne Flagg

All ETDs from UAB

Drawing on the sociological theories of fundamental causes and social support, it was hypothesized that exercise during pregnancy would be positively associated with both socioeconomic status (SES) and social support for exercise and that the association between SES and exercise levels would be at least partially explained by attitudes towards exercise. It was also hypothesized that there would be a positive interaction between SES and social support for exercise in relation to exercise levels during pregnancy. Cross-sectional observational data was obtained from a survey of pregnant women, predominantly from those accessing prenatal care at Birmingham, AL area obstetric clinics. The …

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Characteristics And Behaviors Based On Introduction To Opioids Among Adults In Buprenorphine/Naloxone Treatment, Angela R. Gallien Jan 2015

Characteristics And Behaviors Based On Introduction To Opioids Among Adults In Buprenorphine/Naloxone Treatment, Angela R. Gallien

All ETDs from UAB

Buprenorphine/naloxone (BNT) is a pharmacological treatment for opioid use disorders and is available by prescription in an office-based setting from physicians with specialized training. The purpose of this study was to identify the characteristics and behaviors among adults on BNT with the intent to identify the linear combination of variables that account for the differences based on the origins of opioid use. Four opioid user groups were identified a priori: recreational users (RU); self-treaters (ST); medical users misusing (MUM); and medical users not misusing (MU). The dependent variables were mental health and mood, pain and medical problems, internal or external …

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Chief Executive Officer Characteristics In Relationship With Patient Experience Scores Of Hospital Value Based Purchasing, Christina Galstian Jan 2015

Chief Executive Officer Characteristics In Relationship With Patient Experience Scores Of Hospital Value Based Purchasing, Christina Galstian

All ETDs from UAB

ABSTRACT Patient experience scores have become important indicators of value in healthcare. This study was the first of its kind to examine CEO gender, tenure, and education in relationship with patient experience scores and all other value based purchasing scores, such as outcome, efficiency, clinical process of care, and total performance scores. This study suggested that hospitals with certain types of CEOs may perform better with respect to patient experiences and other value based purchasing scores. The primary analysis of this study was to examine the impact of hospital CEO characteristics (tenure, education, gender) on patient experience scores. A supplementary …

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Benefit Finding Among Caregivers Of Childhood Cancer Survivors, Molly Gardner Jan 2015

Benefit Finding Among Caregivers Of Childhood Cancer Survivors, Molly Gardner

All ETDs from UAB

With improved survival rates for children diagnosed with cancer brings a focus on the psychological adjustment of both children and caregivers. Benefit finding, defined as positive change in the face of adversity, has been documented among caregivers of children with cancer and other chronic illness conditions. The first manuscript is a comprehensive literature review of studies investigating benefit finding among caregivers of children with chronic illness conditions, including caregiver demographic and psychosocial, and child demographic and medical predictors, as well as outcomes of benefit finding. The second manuscript reports on predictors of benefit finding in a sample of caregivers of …

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The Role Of The Teacher In Family Involvement: A Multiple Case Study, Terri Garrison Jan 2015

The Role Of The Teacher In Family Involvement: A Multiple Case Study, Terri Garrison

All ETDs from UAB

The purpose of this qualitative multiple case study was to explore the teacher's role in family involvement in preschool classrooms. Family involvement has been a relevant topic for early childhood educators for many years (Hoover-Dempsey & Sandler, 1995). When families are involved in their child's school experience, it has added a positive benefit to the child's development (Chavkin, 2005; Swick, 2004; Marcon, 1999). Regardless of this widely held belief, many families face barriers that prevent involvement from occurring (Gallimore & Goldenberg, 2001; Lamb-Parker, Piotrkowski, Baker, Kessler-Sklar, Clark, & Peay, 2001). This multiple case study was designed to answer the following …

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Safety Culture And Patient Harm, Alfonso Gatmaitan Jan 2015

Safety Culture And Patient Harm, Alfonso Gatmaitan

All ETDs from UAB

SAFETY CULTURE AND PATIENT HARM EVENTS: A CONTINGENCY THEORY PERSPECTIVE IN THE CONTEXT OF COMPLEX ADAPTIVE SYSTEMS ALFONSO GATMAITAN ADMINISTRATION-HEALTH SERVICES ABSTRACT This study examines the correlation between a Culture of Patient Safety as measured by hospital staff surveys and actual patient harm attributed to hospital performance. It is generally accepted by health care management leaders that the presence of a strong culture of patient safety has become a critical component in reducing patient harm. However, little empirical evidence within multiple hospitals over time exists to support this belief. Healthcare managers can utilize this evidence in formulating patient safety improvement …

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A Redescription Of The Cretaceous Marine Turtle Ctenochelys Acris Zangerl, 1953 And A Systematic Revision Of The 'Toxochelyid'-Grade Taxa Using Cladistic Analysis, Andrew Douglas Gentry Jan 2015

A Redescription Of The Cretaceous Marine Turtle Ctenochelys Acris Zangerl, 1953 And A Systematic Revision Of The 'Toxochelyid'-Grade Taxa Using Cladistic Analysis, Andrew Douglas Gentry

All ETDs from UAB

Within this thesis are two separate articles, each representing a distinct chapter. The first chapter is a redescription of the ‘toxochelyid’-grade marine turtle Ctenochelys acris Zangerl, 1953. This redescription, based on several nearly complete specimens from the early Campanian Mooreville Chalk of Alabama, reveals multiple previously undescribed autapomorphic characteristics of this species and contributes significantly to our understanding of ‘toxochelyid’ alpha taxonomy. The second chapter is comprised entirely of the results of multiple cladistic analyses of the ‘toxochelyid’-grade taxa that produce a hypothesized phylogenetic system of classification for this clade. 108 characters from the cranium, carapace, plastron, and appendicular skeleton …

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On Fire Or Burnt Out? The Social Psychological Health Of United Methodist Pastors, Philip Gibson Jan 2015

On Fire Or Burnt Out? The Social Psychological Health Of United Methodist Pastors, Philip Gibson

All ETDs from UAB

This study examines the social processes and structures that shape the social psychological health of United Methodist pastors. These individuals play a central role in a religious institution that is in a state of decline in the 21st century United States. In addition, burnout, a state of compromised social psychological health related to work involving relationships, is a salient issue among clergy. Using a qualitative approach based in grounded theory methodology, 31 semi-structured interviews were conducted with current and former United Methodist pastors, including those in a supervisory role within the Church hierarchy. Using grounded theory coding practices, data from …

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Kinomic Profiling And Drug Screening Of Three-Dimensional Glioblastoma Microtumors As A Potential Comparative Model To Orthotopic Xenolines, Ashley Nichole Gilbert Jan 2015

Kinomic Profiling And Drug Screening Of Three-Dimensional Glioblastoma Microtumors As A Potential Comparative Model To Orthotopic Xenolines, Ashley Nichole Gilbert

All ETDs from UAB

Glioblastoma multiforme (GBM), the most common form of primary malignant brain cancer in adults, is a devastating disease for which effective treatment has remained elusive for over 75 years. A likely reason for the minimal progress during this time is the lack of accurate preclinical models to represent the patient in vivo environment, causing a disconnect in drug therapy effectiveness between the laboratory and clinic. Our proposed solution to address this disconnect and the issues of traditional preclinical modeling is to use innovative HuBiogel-based MicroTumors as a three-dimensional (3D) drug screening model for GBM. Six subcutaneous patient-derived xenografts (PDXs) prepared …

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Role Of Macrophages In The Cardiomyopathy Associated With Obesity And Type 2 Diabetes, Mehak Goel Jan 2015

Role Of Macrophages In The Cardiomyopathy Associated With Obesity And Type 2 Diabetes, Mehak Goel

All ETDs from UAB

Obesity is a state of chronic low-grade systemic inflammation that, along with type 2 diabetes (T2D), increases the risk of developing cardiovascular disease (CVD). Despite the wealth of information on the link between macrophages and cytokines in adipose tissue and peripheral insulin resistance, their role in the pathogenesis of diabetic cardiomyopathy and cardiac diastolic dysfunction is unclear. We hypothesized that activated immune cell mediators, in particular monocytes and macrophages, are fundamental drivers of diet-induced obesity and diabetic cardiomyopathy. Herein, firstly, a diet-induced model of diabetic cardiomyopathy was developed in C57BL/6 mice by feeding a high fat diet (HFD, 45% kcal …

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Consequences Of Trps1 Deficiency On Dentinogenesis, Morgan Goss Jan 2015

Consequences Of Trps1 Deficiency On Dentinogenesis, Morgan Goss

All ETDs from UAB

Dentinogenesis is a complex process of dentin formation. It involves differentiation of odontoblasts, the cells that make dentin, and the formation of a unique extracellular matrix, known as dentin. Dentin is ultimately produced through the interaction of collagen fibers, non-collagenous proteins and hydroxyapatite (HA) crystals. Odontoblasts are cranial neural crest (CNC) ectomesenchymal derived cells. Trps1 is a novel transcription factor believed to play an important role in both tooth formation and the mineralization process. TRPS1 gene mutations are known to result in dental and skeletal abnormalities manifested in humans as tricho-rhino-phalangeal syndrome (TRPS) and Ambras syndrome. Trps1 expression varies throughout …

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Unmanned Ground Vehicle Terrain/Road Mobility Foundation And Its Algorithmic Formalization For Wheel Power Management To Improve Leader And Follower Capabilities, Jeremy P. Gray Jan 2015

Unmanned Ground Vehicle Terrain/Road Mobility Foundation And Its Algorithmic Formalization For Wheel Power Management To Improve Leader And Follower Capabilities, Jeremy P. Gray

All ETDs from UAB

The implementation of the autonomy-enabled technologies to improve soldier safety and battlefield distribution for the Ground Distribution fleet, by using semi-autonomous leader and follower capabilities, has begun. The need for tactical and operational mobility and agility is a key element in this process. Their success significantly depends on mobility of the convoy vehicles in terrain and road conditions. Although, existing methods have successfully improved vehicle mobility, those methods have exhausted their potential. There is a need for a new technological paradigm that would lead to a breakthrough in vehicle and convoy mobility research and engineering. Mobility strongly depends on the …

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County-Level Homicide In The United States: An Analysis From A Social Disorganization Perspective, Julien Grayer Jan 2015

County-Level Homicide In The United States: An Analysis From A Social Disorganization Perspective, Julien Grayer

All ETDs from UAB

The United States has the highest rates of homicide among industrialized nations. The analysis of variations in the homicide rate lends itself to interpretation through various theoretical frameworks, one of which is social disorganization. Social disorganization is commonly used as a means to discuss crime in the context of neighborhoods and communities. The argument of social disorganization is that criminal activity is curbed by collective efficacy. That collective efficacy is affected by structural variables such as poverty, residential stability, and heterogeneity. The question then became whether social disorganization could be utilized for county-level analysis. The results showed that social disorganization …

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The Effect Of Applied Stress On Knowledge Retention In A Multiwall Virtual Environment, David Wayne Brown Jan 2015

The Effect Of Applied Stress On Knowledge Retention In A Multiwall Virtual Environment, David Wayne Brown

All ETDs from UAB

While the science of medicine continues to grow as new discoveries in the treatment of disease are made, the education of existing procedures has not evolved with the growth of new technology. The training of doctors and nurses is still, primarily, one of classrooms and presentations. In addition, this training is predominately focused on treating the patient once they have reached the hospital, with limited thought given to out of hospital emergencies. Simulation labs are present at most schools, but these are limited in their ability to deliver identical scenarios across the entire student population due to variances in personnel …

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Lab-On-A-Brane: A Novel Physiologically Relevant Planar Arterial Model To Study Transendothelial Transport, Karim I. Budhwani Jan 2015

Lab-On-A-Brane: A Novel Physiologically Relevant Planar Arterial Model To Study Transendothelial Transport, Karim I. Budhwani

All ETDs from UAB

The tremendous quality of life impact notwithstanding, cardiovascular diseases and Cancer add up to over US$ 700bn each year in financial costs alone. Aging and population growth are expected to further expand the problem space while drug research and development remain expensive. However, preclinical costs can be substantially mitigated by substituting animal models with in vitro devices that accurately model human cardiovascular transport. Here we present a novel physiologically relevant lab-on-a-brane that simulates in vivo pressure, flow, strain, and shear waveforms associated with normal and pathological conditions in large and small blood vessels for studying molecular transport across the endothelial …

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Effects Of Transcranial Direct Current Stimulation (Tdcs) On Symptoms Of Binge Eating Disorder (Bed) And Sub-Threshold Bed, Emilee Elizabeth Burgess Jan 2015

Effects Of Transcranial Direct Current Stimulation (Tdcs) On Symptoms Of Binge Eating Disorder (Bed) And Sub-Threshold Bed, Emilee Elizabeth Burgess

All ETDs from UAB

The present study investigated the efficacy of a single administration of transcranial direct current stimulation (tDCS) to reduce binge eating symptoms, namely food consumption, food cravings, and binge urges, in individuals clinically diagnosed with BED and sub-threshold BED. The study used a within-subjects crossover design whereby each participant received both a real and a sham condition of tDCS in counterbalanced order. Results indicated that tDCS significantly reduced caloric intake of specifically preferred foods during an in-lab eating test, decreased food cravings induced by food photo images, and decreased binge desire on the same day as treatment, compared to sham stimulation. …

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Exploring The Relationship Between Study Abroad And Emotional Intelligence, Michael Joshua Carter Jan 2015

Exploring The Relationship Between Study Abroad And Emotional Intelligence, Michael Joshua Carter

All ETDs from UAB

EXPLORING THE RELATIONSHIP BETWEEN STUDY ABROAD AND EMOTIONAL INTELLIGENCE MICHAEL JOSHUA CARTER EDUCATIONAL LEADERSHIP ABSTRACT Given the increased interest in the academic and behavioral impact of university study abroad programs, the possible relationship between study abroad and emotional intelligence was evaluated. A paper-based survey packet consisting of a researcher-developed demographic questionnaire and the Bar-On EQ-i: 2.0 Emotional Intelligence Quotient Inventory (EQi) was administered to a convenience sample of 144 undergraduate students, ages 19-25, at the University of Alabama at Birmingham. The total sample consisted of two groups: (1) a sample group of undergraduate students who participated in the university study …

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The Adaptive Significance Of Phenotypic Plasticity In The Wild: An Experimental Test Using The Brown Anole Lizard (Anolis Sagrei), Corey Dale Cates Jan 2015

The Adaptive Significance Of Phenotypic Plasticity In The Wild: An Experimental Test Using The Brown Anole Lizard (Anolis Sagrei), Corey Dale Cates

All ETDs from UAB

The conditions that embryos experience during development have substantial effects on offspring phenotypes and fitness. Although plastic responses to developmental environments are widespread, whether they are adaptive is unknown in most cases. Developmental plasticity is often thought to be adaptive in heterogeneous environments, but it can also enhance fitness when environments experienced by embryos provide cues for the conditions they will eventually experience later in life. Under the latter scenario, early embryonic conditions could program an individual’s physiology to appropriately deal with predictable future conditions. This hypothesis has received support in the ecological and medical literature on diverse organisms. However, …

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Intra-Oral Scanning Devices Compared To Traditional Digital Impressions, Terpsithea Christou Jan 2015

Intra-Oral Scanning Devices Compared To Traditional Digital Impressions, Terpsithea Christou

All ETDs from UAB

The aim of this study is to review the state of art concerning 3D optical acquisition techniques and devices currently used in Orthodontics, and determine whether a commercial intra-oral scanner is as accurate as traditional impressions for orthodontic purposes. Materials and Methods: Records of 30 subjects were prospectively acquired and digital models were obtained using an intra-oral scanner, LythosTM by Ormco, and an extra-oral scanner, GOM ATOS Triple Scan II by GOM. Seven parameters indicating linear measurements from predetermined landmarks were measured and analyzed. Paired t tests, plots and bars and Bland and Altman Analysis were used to compare and …

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