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2015

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Design Of High Speed Computer Networks Aimed At Reducing Energy Consumption And Carbon Emission At Georgia Southern University, Danda Rawat, Mujibur Khan, Spencer Harp Jul 2015

Design Of High Speed Computer Networks Aimed At Reducing Energy Consumption And Carbon Emission At Georgia Southern University, Danda Rawat, Mujibur Khan, Spencer Harp

Sustainability Showcase (2014-2022)

Design of High Speed Computer Networks Aimed at Reducing Energy Consumption and Carbon Emission at Georgia Southern University

Danda B. Rawat, PhD ($31,065.40)

The main focus of this research was to design OpenFlow based networks that will result in high-speed computer networks and dramatic reductions of energy consumption and carbon emission. An experimental OpenFlow based network was established and tested in the CWiNs lab of Georgia Southern University with the specific purpose of demonstrating the significant energy savings and reduction in carbon waste that can be achieved while providing reliable and fast networking services at Georgia Southern University.


Oxidized And Reduced [2fe-2s] Clusters From An Iron(I) Synthon, Megan E. Reesbeck, Meghan M. Rodriguez, William W. Brennessel, Brandon Q. Mercado, David Vinyard, Patrick L. Holland Jul 2015

Oxidized And Reduced [2fe-2s] Clusters From An Iron(I) Synthon, Megan E. Reesbeck, Meghan M. Rodriguez, William W. Brennessel, Brandon Q. Mercado, David Vinyard, Patrick L. Holland

Faculty Publications

© 2015 SBIC. Abstract Synthetic [2Fe-2S] clusters are often used to elucidate ligand effects on the reduction potentials and spectroscopy of natural electron-transfer sites, which can have anionic Cys ligands or neutral His ligands. Current synthetic routes to [2Fe-2S] clusters are limited in their feasibility with a range of supporting ligands. Here, we report a new synthetic route to synthetic [2Fe-2S] clusters, through oxidation of an iron(I) source with elemental sulfur. This method yields a neutral diketiminate-supported [2Fe-2S] cluster in the diiron(III)-oxidized form. The oxidized [2Fe-2S] cluster can be reduced to a mixed valent iron(II)-iron(III) compound. Both the diferric and …


A Novel Glp1 Receptor Interacting Protein Atp6ap2 Regulates Insulin Secretion In Pancreatic Beta Cells, Feihan F. Dai Jul 2015

A Novel Glp1 Receptor Interacting Protein Atp6ap2 Regulates Insulin Secretion In Pancreatic Beta Cells, Feihan F. Dai

Faculty Publications

GLP1 activates its receptor, GLP1R, to enhance insulin secretion. The activation and transduction of GLP1R requires complex interactions with a host of accessory proteins, most of which remain largely unknown. In this study, we used membrane-based split ubiquitin yeast two-hybrid assays to identify novel GLP1R interactors in both mouse and human islets. Among these, ATP6ap2 (ATPase H-transporting lysosomal accessory protein 2) was identified in both mouse and human islet screens. ATP6ap2 was shown to be abundant in islets including both alpha and beta cells. When GLP1R and ATP6ap2 were co-expressed in beta cells, GLP1R was shown to directly interact with …


Bronchoscopie En Milieu Hospitalier : Évaluation Des Expositions Aux Bioaérosols, Jacques Lavoie, Geneviève Marchand, Yves Cloutier, Yves Beaudet, Stéphane Hallé, Sylvie Nadeau, Gilbert Pichette, Caroline Duchaine Jul 2015

Bronchoscopie En Milieu Hospitalier : Évaluation Des Expositions Aux Bioaérosols, Jacques Lavoie, Geneviève Marchand, Yves Cloutier, Yves Beaudet, Stéphane Hallé, Sylvie Nadeau, Gilbert Pichette, Caroline Duchaine

Rapports de recherche scientifique

Lors des examens de bronchoscopie en milieu hospitalier, des aérosols provenant de la bouche et du nez du patient peuvent se retrouver en suspension dans l’air ambiant. Les aérosols produits peuvent contenir des microorganismes pathogènes, tels des mycobactéries, des bactéries, des virus et même des moisissures. Ces microorganismes peuvent également être aérosolisés lors du nettoyage des bronchoscopes effectué après l’examen. Selon la nature de ces microorganismes ou bioaérosols, ils peuvent persister assez longtemps dans l’air et potentiellement causer des infections chez les travailleurs exposés. L’objectif principal de cette recherche est de mesurer les concentrations des particules totales et biologiques lors …


Urban Evolution: The Role Of Water, Sujay S. Kaushal, William H. Mcdowell, Wilfred M. Wollheim, Tamara A. Newcomer Johnson, Paul M. Mayer, Kenneth T. Belt, Michael J. Pennino Jul 2015

Urban Evolution: The Role Of Water, Sujay S. Kaushal, William H. Mcdowell, Wilfred M. Wollheim, Tamara A. Newcomer Johnson, Paul M. Mayer, Kenneth T. Belt, Michael J. Pennino

Faculty Publications

The structure, function, and services of urban ecosystems evolve over time scales from seconds to centuries as Earth’s population grows, infrastructure ages, and sociopolitical values alter them. In order to systematically study changes over time, the concept of “urban evolution” was proposed. It allows urban planning, management, and restoration to move beyond reactive management to predictive management based on past observations of consistent patterns. Here, we define and review a glossary of core concepts for studying urban evolution, which includes the mechanisms of urban selective pressure and urban adaptation. Urban selective pressure is an environmental or societal driver contributing to …


Students Learn About Marine Science Careers At Ole Miss Rov Camp, Christina Steube Jul 2015

Students Learn About Marine Science Careers At Ole Miss Rov Camp, Christina Steube

University of Mississippi News

No abstract provided.


Bjc Today Jul 2015

Bjc Today

BJC Today

No abstract provided.


Tight Junction Cldn2 Gene Is A Direct Target Of The Vitamin D Receptor, Yong-Guo Zhang, Shaoping Wu, Rong Lu, David Zhou, Jingsong Zhou, Geert Carmeliet, Elaine Petrof, Erika C. Claud, Jun Sun Jul 2015

Tight Junction Cldn2 Gene Is A Direct Target Of The Vitamin D Receptor, Yong-Guo Zhang, Shaoping Wu, Rong Lu, David Zhou, Jingsong Zhou, Geert Carmeliet, Elaine Petrof, Erika C. Claud, Jun Sun

Faculty and Staff Publications

The breakdown of the intestinal barrier is a common manifestation of many diseases. Recent evidence suggests that vitamin D and its receptor VDR may regulate intestinal barrier function. Claudin-2 is a tight junction protein that mediates paracellular water transport in intestinal epithelia, rendering them "leaky". Using whole body VDR(-/-) mice, intestinal epithelial VDR conditional knockout (VDR(ΔIEC)) mice, and cultured human intestinal epithelial cells, we demonstrate here that the CLDN2 gene is a direct target of the transcription factor VDR. The Caudal-Related Homeobox (Cdx) protein family is a group of the transcription factor proteins which bind to DNA to regulate the …


A Quantitative Perspective On Surface Marker Selection For The Isolation Of Functional Tumor Cells, Calvin F. Cahall, Jacob L. Lilly, Edward A. Hirschowitz, Brad J. Berron Jul 2015

A Quantitative Perspective On Surface Marker Selection For The Isolation Of Functional Tumor Cells, Calvin F. Cahall, Jacob L. Lilly, Edward A. Hirschowitz, Brad J. Berron

Chemical and Materials Engineering Faculty Publications

Much effort has gone into developing fluid biopsies of patient peripheral blood for the monitoring of metastatic cancers. One common approach is to isolate and analyze tumor cells in the peripheral blood. Widespread clinical implementation of this approach has been hindered by the current choice of targeting epithelial markers known to be highly variable in primary tumor sites. Here, we review current antigen-based tumor cell isolation strategies and offer biological context for commonly studied cancer surface markers. Expression levels of the most common markers are quantitated for three breast cancer and two non-small cell lung cancer (NSCLC) lineage models. These …


Targeted Dna Damage At Individual Telomeres Disrupts Their Integrity And Triggers Cell Death, Luxi Sun, Rong Tan, Jianquan Xu, Justin Laface, Ying Gao, Yanchun Xiao, Myriam Attar, Carola Neumann, Guo-Min Li, Bing Su, Yang Liu, Satoshi Nakajima, Arthur S. Levine, Li Lan Jul 2015

Targeted Dna Damage At Individual Telomeres Disrupts Their Integrity And Triggers Cell Death, Luxi Sun, Rong Tan, Jianquan Xu, Justin Laface, Ying Gao, Yanchun Xiao, Myriam Attar, Carola Neumann, Guo-Min Li, Bing Su, Yang Liu, Satoshi Nakajima, Arthur S. Levine, Li Lan

Markey Cancer Center Faculty Publications

Cellular DNA is organized into chromosomes and capped by a unique nucleoprotein structure, the telomere. Both oxidative stress and telomere shortening/dysfunction cause aging-related degenerative pathologies and increase cancer risk. However, a direct connection between oxidative damage to telomeric DNA, comprising <1% of the genome, and telomere dysfunction has not been established. By fusing the KillerRed chromophore with the telomere repeat binding factor 1, TRF1, we developed a novel approach to generate localized damage to telomere DNA and to monitor the real time damage response at the single telomere level. We found that DNA damage at long telomeres in U2OS cells is not repaired efficiently compared to DNA damage in non-telomeric regions of the same length in heterochromatin. Telomeric DNA damage shortens the average length of telomeres and leads to cell senescence in HeLa cells and cell death in HeLa, U2OS and IMR90 cells, when DNA damage at non-telomeric regions is undetectable. Telomere-specific damage induces chromosomal aberrations, including chromatid telomere loss and telomere associations, distinct from the damage induced by ionizing irradiation. Taken together, our results demonstrate that oxidative damage induces telomere dysfunction and underline the importance of maintaining telomere integrity upon oxidative damage.


Addressing Therapeutic Options For Ebola Virus Infection In Current And Future Outbreaks, Azizul Haque, Didier Hober, Joel Blondiaux Jul 2015

Addressing Therapeutic Options For Ebola Virus Infection In Current And Future Outbreaks, Azizul Haque, Didier Hober, Joel Blondiaux

Dartmouth Scholarship

Ebola virus can cause severe hemorrhagic disease with high fatality rates. Currently, no specific therapeutic agent or vaccine has been approved for treatment and prevention of Ebola virus infection of humans. Although the number of Ebola cases has fallen in the last few weeks, multiple outbreaks of Ebola virus infection and the likelihood of future exposure highlight the need for development and rapid evaluation of pre- and postexposure treatments. Here, we briefly review the existing and future options for anti-Ebola therapy, based on the data coming from rare clinical reports, studies on animals, and results from in vitro models. We …


Nanofiber Based Carbon Capture Technology To Reduce The Co2 Emissions In Georgia Southern University Campus, Mujibur Khan, Spencer Harp Jul 2015

Nanofiber Based Carbon Capture Technology To Reduce The Co2 Emissions In Georgia Southern University Campus, Mujibur Khan, Spencer Harp

Sustainability Showcase (2014-2022)

Nanofiber Based Carbon Capture Technology to Reduce the CO2 Emissions in Georgia Southern University Campus

PI: Dr. Mujibur Rahman Khan Co-PI: Spencer Harp

A transformative idea of nano fibers based on CO2 capturing filter technology to reduce the CO2 emission from the Machine Shops, Dining Commons, and Georgia Southern University Vehicles.


My News Jul 2015

My News

My News (2014-2020)

  • Georgia Southern Professor Garners National Attention for Recent Book
  • Active­Duty Military Invited to Attend Georgia Southern Museum at No Charge
  • Georgia Southern's Black Gold
  • Sun Belt Media Day Signals the Start of Georgia Southern Football 2015­2016


The Role Of Motivation In Second Language Acquisition: The Critical Constructs Of L2 Motivation, Nicholas Cross Jul 2015

The Role Of Motivation In Second Language Acquisition: The Critical Constructs Of L2 Motivation, Nicholas Cross

Electronic Theses and Dissertations Archive

L2 motivation, as it has been defined in Robert Gardner's composite construct of the integrative motive, has been determined to be essential in the acquisition of a second language. Though some modern researchers have reconceptualized the construct, they have nonetheless reaffirmed its critical components through their own studies. This study explored the phenomenological orientation of the perception of the importance of L2 motivation as understood my 20 ESL teachers with at least three years of teaching experience through four questions: 1. How important to student language learning success (proficiency) do experienced ESL teachers consider motivation to be? 2. What are …


Amikacin Concentrations Predictive Of Ototoxicity In Multidrug-Resistant Tuberculosis Patients, Chawangwa Modongo, Jotam G. Pasipanodya, Nicola M. Zetola, Scott M. Williams Jul 2015

Amikacin Concentrations Predictive Of Ototoxicity In Multidrug-Resistant Tuberculosis Patients, Chawangwa Modongo, Jotam G. Pasipanodya, Nicola M. Zetola, Scott M. Williams

Dartmouth Scholarship

Aminoglycosides, such as amikacin, are used to treat multidrug-resistant tuberculosis. However, ototoxicity is a common problem and is monitored using peak and trough amikacin concentrations based on World Health Organization recommendations. Our objective was to identify clinical factors predictive of ototoxicity using an agnostic machine learning method. We used classification and regression tree (CART) analyses to identify clinical factors, including amikacin concentration t

hresholds that pre- dicted audiometry-confirmed ototoxicity among 28 multidrug-resistant pulmonary tuberculosis patients in Botswana. Amika- cin concentrations were measured for all patients. The quantitative relationship between predictive factors and the probability of ototoxicity were then identified using …


Week Of July 27, 2015, New York Medical College Jul 2015

Alliance For The Wild Rockies And Native Ecosystems Council V. Krueger, 950 F. Supp. 2d 1196 (D. Mont. 2013), Nicholas R. Vandenbos Jul 2015

Alliance For The Wild Rockies And Native Ecosystems Council V. Krueger, 950 F. Supp. 2d 1196 (D. Mont. 2013), Nicholas R. Vandenbos

Public Land & Resources Law Review

No abstract provided.


Using The New Equal Protection To Challenge Federal Control Over Tribal Lands, Alex T. Skibine Jul 2015

Using The New Equal Protection To Challenge Federal Control Over Tribal Lands, Alex T. Skibine

Public Land & Resources Law Review

No abstract provided.


Medical School Watercooler Newsletter - July 26, 2015, Lindsey Lyle Jul 2015

Medical School Watercooler Newsletter - July 26, 2015, Lindsey Lyle

Watercooler Newsletter

This is the July 26, 2015 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

USA Welcomes Dr. Maximilian Pyko

Dr. Barrington Receives Grant Award from American Lung Association

SouthMed Prep Scholars Present Research at USA

Tobacco Cessation - Staying on Track


57th Annual Rocky Mountain Conference On Magnetic Resonance Jul 2015

57th Annual Rocky Mountain Conference On Magnetic Resonance

Rocky Mountain Conference on Magnetic Resonance

Final program, abstracts, and information about the 57th annual meeting of the Rocky Mountain Conference on Magnetic Resonance, co-endorsed by the Colorado Section of the American Chemical Society and the Society for Applied Spectroscopy. Held in Snowbird, Utah, July 26-31, 2015.


The Impact Of Marital Quality And Parent-Child Relationships On Peer Relationships At School: A Brazilian Study, Brandon P. Eddy Jul 2015

The Impact Of Marital Quality And Parent-Child Relationships On Peer Relationships At School: A Brazilian Study, Brandon P. Eddy

College of Education and Human Sciences: Dissertations, Theses, and Student Research

The purpose of this thesis was to investigate the impact that marital quality and parent-child relationships have on peer relationships at school in a Brazilian population. Despite the fact that Brazil is the fifth most populated country in the world, it is very underrepresented in the literature and little information is known about how marital quality and the parent-child bond impact children socially. Sixty-five mothers and their children participated in this study. Marital quality was assessed using the Portuguese version of the Revised Dyadic Adjustment Scale. The parent-child relationship was assessed using the Parental Bonding Instrument and peer relationships at …


Cryptic Speciation In The Acari: A Function Of Species Lifestyles Or Our Ability To Separate Species?, Anna Skoracka, Sara Magalhães, Brian G. Rector, Lechosław Kuczyński Jul 2015

Cryptic Speciation In The Acari: A Function Of Species Lifestyles Or Our Ability To Separate Species?, Anna Skoracka, Sara Magalhães, Brian G. Rector, Lechosław Kuczyński

Harold W. Manter Laboratory of Parasitology: Library Materials

There are approximately 55,000 described Acari species, accounting for almost half of all known Arachnida species, but total estimated Acari diversity is reckoned to be far greater. One important source of currently hidden Acari diversity is cryptic speciation, which poses challenges to taxonomists documenting biodiversity assessment as well as to researchers in medicine and agriculture. In this review, we revisit the subject of biodiversity in the Acari and investigate what is currently known about cryptic species within this group. Based on a thorough literature search, we show that the probability of occurrence of cryptic species is mainly related to the …


The Role Of Element Type And Crossed Relation In Restructuring Difficulty, Zhonglu Zhang, Ke Yang, Christopher M. Warren, Guang Zhao, Peng Li, Yi Lei, Hong Li Jul 2015

The Role Of Element Type And Crossed Relation In Restructuring Difficulty, Zhonglu Zhang, Ke Yang, Christopher M. Warren, Guang Zhao, Peng Li, Yi Lei, Hong Li

Psychology Faculty Publications

Chunk decomposition is an aspect of problem solving that involves decomposing a pattern into its component parts in order to regroup them into a new pattern. Previous work suggests that the primary source of difficulty in chunk decomposition is whether a problem’s solution requires removing a part that is a meaningful perceptual pattern (termed a chunk) or not (a non-chunk). However, the role of spatial overlap (crossed relation or not) has been ignored in this line of research. Here, we dissociated the role of element type and crossed relation in chunk decomposition problems by employing a Chinese character transformation task. …


Protective Properties Of Functionalised Tetrazine On An Aerospace Aluminium Alloy (Aa 2024-T3), Swarna Jaiswal, P.C. Rajath Varma, Brendan Duffy, Felicia Mutuma, Patrick Mchale Jul 2015

Protective Properties Of Functionalised Tetrazine On An Aerospace Aluminium Alloy (Aa 2024-T3), Swarna Jaiswal, P.C. Rajath Varma, Brendan Duffy, Felicia Mutuma, Patrick Mchale

Articles

Environmental health concerns over conventional chromium based surface treatments on aluminium substrates are well known. Current research efforts have concentrated on developing protective technologies for multiple applications. Such properties would enable manufacturers to address both corrosion and bacterial threats in areas such as fuel tanks and delivery systems.

The present study explores the anticorrosion properties of 1,2-dihydro 1, 2, 4, 5 tetrazine-3, 6-dicarboxylic acid (H2DCTZ) on a copper rich aerospace aluminium alloy (AA 2024-T3). Furthermore the antimicrobial activity of the tetrazine is evaluated against Gram-positive and Gram-negative bacteria, both capable of inducing corrosion. The protective action of the …


Occurrence Of An Herbicide-Resistant Plant Trait In Agricultural Field Margins, Karla L. Gag, David J. Gibson, Bryan G. Young, Julie M. Young, Joseph L. Matthews, Stephen C. Weller, Robert G. Wilson Jul 2015

Occurrence Of An Herbicide-Resistant Plant Trait In Agricultural Field Margins, Karla L. Gag, David J. Gibson, Bryan G. Young, Julie M. Young, Joseph L. Matthews, Stephen C. Weller, Robert G. Wilson

Department of Agronomy and Horticulture: Faculty Publications

Agricultural environments allow study of evolutionary change in plants. An example of evolution within agroecological systems is the selection for resistance to the herbicide glyphosate within the weed, Conyza canadensis. Changes in survivorship and reproduction associated with the development of glyphosate resistance (GR) may impact fitness and influence the frequency of occurrence of the GR trait. We hypothesized that site characteristics and history would affect the occurrence of GR C. canadensis in field margins. We surveyed GR occurrence in field margins and asked whether there were correlations between GR occurrence and location, crop rotation, GR crop trait rotation, crop type, …


Diagnostic Imaging Of Cervical Intraepithelial Neoplasia Based On Hematoxylin And Eosin Fluorescence, Mario R. Castellanos, Anita Szerszen, Stephen Gundry, Edyta C. Pirog, Mitchell Maiman, Sritha Rajupet, John Paul Gomez, Adi Davidov, Priya Ranjan Debata, Probal Banerjee, Jimmie E. Fata Jul 2015

Diagnostic Imaging Of Cervical Intraepithelial Neoplasia Based On Hematoxylin And Eosin Fluorescence, Mario R. Castellanos, Anita Szerszen, Stephen Gundry, Edyta C. Pirog, Mitchell Maiman, Sritha Rajupet, John Paul Gomez, Adi Davidov, Priya Ranjan Debata, Probal Banerjee, Jimmie E. Fata

Publications and Research

Background Pathological classification of cervical intraepithelial neoplasia (CIN) is problematic as it relies on subjective criteria. We developed an imaging method that uses spectroscopy to assess the fluorescent intensity of cervical biopsies derived directly from hematoxylin and eosin (H&E) stained tissues. Methods Archived H&E slides were identified containing normal cervical tissue, CIN I, and CIN III cases, from a Community Hospital and an Academic Medical Center. Cases were obtained by consensus review of at least 2 senior pathologists. Images from H&E slides were captured first with bright field illumination and then with fluorescent illumination. We used a Zeiss Axio Observer …


To Speak The Word Of God With Our Hands For Those Who Hear With Their Eyes, Miriam Nancy Lopez Jul 2015

To Speak The Word Of God With Our Hands For Those Who Hear With Their Eyes, Miriam Nancy Lopez

LMU Theses and Dissertations

Deaf people often have been outsiders in a hearing Church. Ninety-five percent of Deaf people are born to hearing parents. This is a Community that is doubly marginalized for they are Latino/as and Deaf. Therefore, I will present the needs of Deaf Latino/a Catholics in order for the Church to recognize them as a Community of faith. First, I present how language impacts the development of culture and identity. Second, how this community of Deaf Latino/as is trying to make sense of their identity as they are being raised in the United States. Finally, I present a plan to bridge …


Hazardous Biological Activities In Outer Space, Philip Mcgarrigle Jul 2015

Hazardous Biological Activities In Outer Space, Philip Mcgarrigle

Akron Law Review

The purpose of this article is to focus on space acts that may be classified as ultrahazardous (specifically microbiological research) and to discuss how these activities are or will be affected by current or future legal regulations. Legal standards from both a United States and an international perspective will be discussed.


A Summary Of Issues Involving Marine Mammals And Highly Migratory Species, John Warren Kindt Jul 2015

A Summary Of Issues Involving Marine Mammals And Highly Migratory Species, John Warren Kindt

Akron Law Review

The conservation and protection of marine mammals is one of many serious problems relating to exploitation of the living resources of the ocean. While other problems, for example the management of fish stocks and the protection of anadromous, catadromous, and highly migratory species, receive a great deal of attention in the Convention on the Law of the Sea (LOS Convention), negotiated by the Third U.N. Conference on the Law of the Sea (UNCLOS III), the problem of marine mammals is addressed directly in only two provisions. Certainly, varying political and economic interests impede negotiation of a comprehensive international protective regime; …


Slis Connecting, Volume 4, Issue 1, Stacy Creel, Teresa Welsh Jul 2015

Slis Connecting, Volume 4, Issue 1, Stacy Creel, Teresa Welsh

SLIS Connecting

Entire issue of SLIS Connecting, Volume 4, Issue 1