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2015

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Life Balance In Nurse Educators: A Mixed Methods Study, Joan Marie Owens Aug 2015

Life Balance In Nurse Educators: A Mixed Methods Study, Joan Marie Owens

Dissertations

No abstract provided.


Exploring A Culture Of Learning With Technology: An Ethnographic Content Analysis Of The Activity Of Learning With Educational Ipad Apps, Akio Yamanaka Aug 2015

Exploring A Culture Of Learning With Technology: An Ethnographic Content Analysis Of The Activity Of Learning With Educational Ipad Apps, Akio Yamanaka

Dissertations

This study explored the culture of learning with educational iPad apps using

activity theory as a guiding framework. First, the top nine educational apps were tracked

in the Top Charts section of Apple’s App Store for a duration of four months. The nine

sampled apps, selected based on their frequency of appearance, included Toca Hair Salon

2, Stack the States, Endless Alphabet, Mickey Mouse Clubhouse: Wildlife Count Along,

Wild Kratts Creature Power World Adventure, Wallykazam! Letter and Word Magic,

Starfall Learn to Read, Dr. Panda’s Restaurant 2, and Bug Art. The descriptions, version

updates, app content, and customer reviews for …


Candida Albicans Hyphal Mannan Is Structurally Distinct From Yeast Mannan, Francis Kwofie Aug 2015

Candida Albicans Hyphal Mannan Is Structurally Distinct From Yeast Mannan, Francis Kwofie

Electronic Theses and Dissertations

C. albicans is a polymorphic fungal pathogen which has the ability to shift from yeast to hyphae. C. albicans cell wall is composed of glucan, chitin, mannoprotein and mannan. It is not possible, using standard extraction methods, to isolate mannan from C. albicans hyphae. To isolate hyphal mannan, we developed a simplified alkali extraction method. Using this method it was determined that hyphal mannan has a much lower molecular weight, a smaller polymer distribution and altered conformation structure when compared to yeast mannan. The hyphal mannan was found to contain little to no acid-labile portion with only α-Man-PO4 groups …


Use Of The Physical Classroom Environment As A Teaching And Learning Tool Including The Impact Of The Ccssi In Kindergarten Through Third Grade Classrooms In Northeast Tennessee, Charity Hensley-Pipkin Aug 2015

Use Of The Physical Classroom Environment As A Teaching And Learning Tool Including The Impact Of The Ccssi In Kindergarten Through Third Grade Classrooms In Northeast Tennessee, Charity Hensley-Pipkin

Electronic Theses and Dissertations

The specific goal of this study was to determine the use of the physical classroom environment as a teaching and learning tool in an era of the implementation of the Common Core State Standards Initiative (CCSSI). This qualitative multi-case study focused on the learning principles and epistemological beliefs of primary teachers with reference to the physical classroom environment and the teaching process in regard to meeting the expectations set forth by the CCSSI. The researcher sought participation from a city school district in Northeast Tennessee which included a total of 8 participating teachers consisting of 2 each of grades kindergarten, …


Algr Directly Controls Rsma In Pseudomonas Aeruginosa, Tyler Speaks Aug 2015

Algr Directly Controls Rsma In Pseudomonas Aeruginosa, Tyler Speaks

Electronic Theses and Dissertations

Pseudomonas aeruginosa is a bacterial pathogen that can infect any human tissue. The lungs of cystic fibrosis patients become chronically infected with Pseudomonas aeruginosa. Virulence factor gene expression is under elaborate regulatory control that remains poorly characterized. Understanding the regulatory hierarchy involved during infection is essential for identifying novel drug targets. RsmA is a post-transcriptional regulatory protein that controls expression of several virulence factors. Previous studies demonstrated alginate regulatory components AlgU and AlgR as regulators of rsmA expression. The aim of this study was to determine how AlgR controls rsmA expression. Western blot analysis of HA-tagged RsmA confirmed lower …


An Analysis Of The Interaction Of Methylphenidate And Nicotine In Adolescent Rats: Effects On Bdnf, Elizabeth D. Freeman Aug 2015

An Analysis Of The Interaction Of Methylphenidate And Nicotine In Adolescent Rats: Effects On Bdnf, Elizabeth D. Freeman

Electronic Theses and Dissertations

This investigation was an analysis of the interaction of adolescent exposure to methylphenidate (MPH; trade name: Ritalin) on nicotine sensitization and conditioned place preference (CPP) in a rodent model and underlying mechanisms of this effect. Animals were treated IP with 1 mg/kg MPH or saline using a ―school day‖ regimen of five days on, two days off, from postnatal day (P) 28-50. During the final two weeks of MPH treatment, animals were either behaviorally sensitized to nicotine (0.5 mg/kg free base) or saline for 10 days, or conditioned to nicotine or saline using the CPP behavioral paradigm. In addition, three …


Risk And Protective Factors Of Internalized Mental Illness Stigma, Kathleen Klik Aug 2015

Risk And Protective Factors Of Internalized Mental Illness Stigma, Kathleen Klik

Electronic Theses and Dissertations

The internalization of mental illness stigma is associated with an array of negative consequences; however, not all individuals experience the deleterious effects of internalized mental illness stigma. The present dissertation focuses on factors associated with internalized stigma, and will be the first to examine simultaneously both risk (i.e., shame, shame proneness and shame aversion, insight, and centrality and valence) and protective factors (social support and self-compassion) of internalized mental illness stigma. Using two of the most widely used assessments of internalized mental illness stigma (i.e., Self-Stigma of Mental Illness Scale [SSMIS] and the Internalized Mental Illness Scale [ISMI]), risk and …


Correlation Of Periodontal Pathogens In Concurrent Endodontic-Periodontal Diseases, Amela Lačević, Federico Foschi, Lejla Pojskić, Naris Pojskić, Kasim Bajrović, Jacques Izard Aug 2015

Correlation Of Periodontal Pathogens In Concurrent Endodontic-Periodontal Diseases, Amela Lačević, Federico Foschi, Lejla Pojskić, Naris Pojskić, Kasim Bajrović, Jacques Izard

Department of Food Science and Technology: Faculty Publications

Objectives: This study investigated the correlation between Tannerella forsythia, Porphyromonas gingivalis, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans at dual sites in concurrent endodonticperiodontal diseases.

Material and methods: Samples were collected from endodontium and periodontium in cases of concurrent endodontic-periodontal diseases from thirty participants. The sensitivity and specificity of SYBR Green real-time PCR was used to identify the targeted species. Absolute number of targeted genome copies in tested samples were extrapolated from respective calibration curve.

Results: No statistical difference was found in the number of detected endodontic-periodontal pathogens between the endodontium and periodontium. The Pearson test …


Genetic Approaches In Comparative And Evolutionary Physiology, Jay F. Storz, Jaime T. Bridgham, Scott A. Kelly, Theodore Garland Jr. Aug 2015

Genetic Approaches In Comparative And Evolutionary Physiology, Jay F. Storz, Jaime T. Bridgham, Scott A. Kelly, Theodore Garland Jr.

Jay F. Storz Publications

Whole animal physiological performance is highly polygenic and highly plastic, and the same is generally true for the many subordinate traits that underlie performance capacities. Quantitative genetics, therefore, provides an appropriate framework for the analysis of physiological phenotypes and can be used to infer the microevolutionary processes that have shaped patterns of trait variation within and among species. In cases where specific genes are known to contribute to variation in physiological traits, analyses of intraspecific polymorphism and interspecific divergence can reveal molecular mechanisms of functional evolution and can provide insights into the possible adaptive significance of observed sequence changes. In …


Prevalence And Predictors Of Habitual Snoring In A Sample Of Saudi Middle-Aged Adults, Siraj O. Wali, Bahaa A. Abaalkhail Aug 2015

Prevalence And Predictors Of Habitual Snoring In A Sample Of Saudi Middle-Aged Adults, Siraj O. Wali, Bahaa A. Abaalkhail

Saudi Medical Journal

Objectives: To determine the prevalence of habitual snoring among a sample of middle-aged Saudi adults, and its potential predictors. Methods: A cross-sectional study was conducted from March 2013 until June 2013 in randomly selected Saudi Schools in Jeddah, Kingdom of Saudi Arabia. The enrolled subjects were 2682 school employees (aged 30-60 years, 52.1% females) who were randomly selected and interviewed. The questionnaire used for the interview included: the Wisconsin Sleep Questionnaire to assess for snoring, medical history, and socio-demographic data. Anthropometric measurements and blood pressure readings were recorded using standard methods. Results: Forty percent of the 2682 enrolled subjects were …


Neonatal Short-Term Outcomes In Infants With Intrauterine Growth Restriction, Monica G. Hasmasanu, Sorana D. Bolboaca, Melinda I. Baizat, Tudor C. Drugan, Gabriela C. Zaharie Aug 2015

Neonatal Short-Term Outcomes In Infants With Intrauterine Growth Restriction, Monica G. Hasmasanu, Sorana D. Bolboaca, Melinda I. Baizat, Tudor C. Drugan, Gabriela C. Zaharie

Saudi Medical Journal

Objectives: To assess the neonatal outcomes in newborns with intrauterine growth restriction (IUGR) in a Romanian population in a 3 level maternity unit. Methods: A matched case-control design, with one control for each patient was used. The case group comprised neonates with birth weight and birth length below the 10th percentile for the gestational age. Individual matching by gender and age of gestation was used to identify the control group. Both cases and controls were selected from the infants admitted to and discharged from the Neonatal Ward, at the First Gynecology Clinic, of the County Emergency Hospital Cluj-Napoca, Cluj-Napoca, Romania, …


Ultrasonographic Assessment Of Splenic Volume And Its Correlation With Body Parameters In A Jordanian Population, Darwish H. Badran, Heba M. Kalbouneh, Maher T. Al-Hadidi, Amjad T. Shatarat, Emad S. Tarawneh, Azmy M. Hadidy, Waleed S. Mahafza Aug 2015

Ultrasonographic Assessment Of Splenic Volume And Its Correlation With Body Parameters In A Jordanian Population, Darwish H. Badran, Heba M. Kalbouneh, Maher T. Al-Hadidi, Amjad T. Shatarat, Emad S. Tarawneh, Azmy M. Hadidy, Waleed S. Mahafza

Saudi Medical Journal

Objectives: To estimate normal linear dimensions and volume of spleen in Jordanians using ultrasonography, and to correlate splenic volume with age and body parameters: height, weight, body surface area (BSA), and body mass index (BMI). Methods: A prospective pilot study was conducted on 205 volunteers (115 males and 90 females) not known to have any conditions likely to be associated with splenomegaly. The study was performed at the Radiology Department, Jordanian University Hospital, Amman, Jordan, between December 2013 and August 2014. All linear dimensions of spleen were measured, and splenic volume (index) was calculated using the standard prolate ellipsoid formula …


A Novel Missense Mutation In The Tbx5 Gene In A Saudi Infant With Holt-Oram Syndrome, Mohammad M. Al-Qattan, Hussam Abou Al-Shaar Aug 2015

A Novel Missense Mutation In The Tbx5 Gene In A Saudi Infant With Holt-Oram Syndrome, Mohammad M. Al-Qattan, Hussam Abou Al-Shaar

Saudi Medical Journal

We report on a Saudi infant with Holt-Oram syndrome caused by a de novo missense mutation of the TBX5 gene. The mutation (Thr72Lys) is novel and has not been previously reported. The cardiac and limb defects in our patient were both severe, and the infant also had micrognathia and cleft palate. Previously reported cases of the Holt-Oram syndrome caused by missense mutations were reviewed and their phenotypes were compared with the phenotype of our patient.


Development And Validation Of A State-Based Measure Of Emotion Dysregulation: The State Difficulties In Emotion Regulation Scale (S-Ders), Jason M. Lavender, Matthew T. Tull, David Dilillo, Terri Messman-Moore, Kim L. Gratz Aug 2015

Development And Validation Of A State-Based Measure Of Emotion Dysregulation: The State Difficulties In Emotion Regulation Scale (S-Ders), Jason M. Lavender, Matthew T. Tull, David Dilillo, Terri Messman-Moore, Kim L. Gratz

Department of Psychology: Faculty Publications

Existing measures of emotion dysregulation typically assess dispositional tendencies and are therefore not well suited for study designs that require repeated assessments over brief intervals. The aim of this study was to develop and validate a state-based multidimensional measure of emotion dysregulation. Psychometric properties of the State Difficulties in Emotion Regulation Scale (S-DERS) were examined in a large representative community sample of young adult women drawn from four sites (N = 484). Exploratory factor analysis suggested a four-factor solution, with results supporting the internal consistency, construct validity, and predictive validity of the total scale and the four subscales: Nonacceptance (i.e., …


The Distribution Of Dissolved Barium Along The U.S. Geotraces North Atlantic Transect: Impact Of Biogeochemical Processes, Circulation And Phase Association, Karen Renee Grissom Aug 2015

The Distribution Of Dissolved Barium Along The U.S. Geotraces North Atlantic Transect: Impact Of Biogeochemical Processes, Circulation And Phase Association, Karen Renee Grissom

Master's Theses

During the last four decades, since the completion of the GEOSECS program, there has been a growing interest in the biogeochemical cycle of barium (Ba) due to its potential as a proxy for interpreting the geologic record. The typical barium distribution exhibits removal in the upper water column and regeneration at depth, consistent with its classification as a bio-intermediate element and similar to the nutrient-like profiles of silicic acid and alkalinity. To better constrain the uses of Ba, trace element clean samples were collected during the North Atlantic US GEOTRACES cruises.

The cycling of barium in the North Atlantic region …


Latitudinal Variation In Thermal Tolerance And Preference Of Fundulus Notatus And F. Olivaceus: Implications For Temperature Mediated Reproductive Isolation, Laura Kristin Stewart Aug 2015

Latitudinal Variation In Thermal Tolerance And Preference Of Fundulus Notatus And F. Olivaceus: Implications For Temperature Mediated Reproductive Isolation, Laura Kristin Stewart

Master's Theses

Temperature is one of the most pervasive and influential abiotic factors affecting the life histories of fish, regulating a host of physiological processes and influencing behavioral thermoregulation. Fundulus notatus, the blackstripe topminnow, and F. olivaceus, the blackspotted topminnow, are widely distributed species located in drainages along the northern part of Gulf of Mexico (30°N latitude) and as far north as southern Illinois (39°N latitude). However, F. notatus has a much broader range reaching up into the Great Lakes (43°N latitude). Due to their broad geographical range, these populations inhabit a wide range of thermal regimes, thus …


Habitat Selection Of Gulf-Strain Striped Bass, Morone Saxatilis: Relationships To Dynamic Abiotic Environmental Characteristics Within The Biloxi River, Mississippi, Jennifer Lynne Green Aug 2015

Habitat Selection Of Gulf-Strain Striped Bass, Morone Saxatilis: Relationships To Dynamic Abiotic Environmental Characteristics Within The Biloxi River, Mississippi, Jennifer Lynne Green

Master's Theses

The purpose of this project was to provide insights about the short- and long-term patterns of habitat selection of Gulf-strain Striped Bass, Morone saxatilis, based on spatially and seasonally variable abiotic environmental characteristics (water temperature, dissolved oxygen (DO), salinity, specific conductivity, and pH) in the Biloxi River, MS system. Juvenile hatchery-reared and feral adult Gulf-strain Striped Bass were acoustically-tagged and continuously monitored via active and passive telemetry from November 2012 – June 2014. Each month the available abiotic environmental characteristics of 40 random locations within the Biloxi River, along with sub-habitat conditions occupied by acoustically-tagged Gulf-strain Striped Bass, were …


Analyses Of Indices Of Abundance For Important Groundfish Species In The Northern Gulf Of Mexico From 1987-2009, Relative To Shrimp Bycatch; With Age And Growth Of Three Sciaenid Species, Allison Renee Odom Aug 2015

Analyses Of Indices Of Abundance For Important Groundfish Species In The Northern Gulf Of Mexico From 1987-2009, Relative To Shrimp Bycatch; With Age And Growth Of Three Sciaenid Species, Allison Renee Odom

Master's Theses

Bycatch in the shrimp fishery became of particular concern in the 1980s during the peak of shrimp harvest in the northern Gulf of Mexico. Shrimp bycatch is of major importance because the majority of catch in the fishery is not intended target species of commercial shrimp, and most of the additional bycatch is returned to the sea dead or dying, inducing higher rates of mortality. This study was developed to assess the potential ecosystem effects of shrimp harvest on thirty selected species/species groups commonly encountered within the shrimp fishery as bycatch. Delta-lognormal modeling (DLM) was used to determine the relative …


Application Of A New Tree-Ring Based Drought Reconstruction Method At Multiple Forest Sites Across Indiana, U.S.A., Kayla Mechelle Pendergrass Aug 2015

Application Of A New Tree-Ring Based Drought Reconstruction Method At Multiple Forest Sites Across Indiana, U.S.A., Kayla Mechelle Pendergrass

Master's Theses

This thesis research used techniques of dendrochronology to investigate the efficacy of using multiple co-occurring species (MCOS) in a climate reconstruction model compared to a single species (SS) in four old-growth forests in Indiana: Pioneer Mothers Memorial Forest (PM), Donaldson Woods (DW), Hoot Woods (HW), and Lilly Dickey Woods (LD). The objectives of this study were to [1] evaluate the climate response of all chronologies (n = 19; 7 species) to determine the most appropriate climate variable for reconstruction and [2] determine if the MCOS model outperforms the SS model at each individual study site. Model comparison was conducted …


Evaluation Of The Protein Recognition Properties Of Peptide Nucleic Acids, Crystal Cox Serrano Aug 2015

Evaluation Of The Protein Recognition Properties Of Peptide Nucleic Acids, Crystal Cox Serrano

Master's Theses

The objective is to evaluate the ability of aminoacyl-tRNA synthetases (aaRS) to recognize the non-standard nucleic acid, PNA (peptide nucleic acid). PNA has immense potential in biomedical applications due to its increased thermostability and nuclease resistance over natural nucleic acids. PNA represents a superior alternative to natural nucleic acids in many biomedical applications due to its specificity, strong binding, and nuclease resistance. This study is the initial data set that indicates PNA are recognized by translation enzymes.


A Poetic Poioumenon: Coterie And Ekphrasis In David Lehman's "The Breeders' Cup", Anna Beth Rowe Aug 2015

A Poetic Poioumenon: Coterie And Ekphrasis In David Lehman's "The Breeders' Cup", Anna Beth Rowe

Master's Theses

David Lehman’s poem “The Breeders’ Cup” uses cross-generational coterie and ekphrasis to create a poetic poioumenon. When read in terms of art criticism, Lehman’s “The Breeders’ Cup” models creative processes from the past and calls for a rehabilitative ethic in postmodern poetics. Lehman follows the ekphrastic form, which associates a poem with a work of visual art, from his New York School predecessor Frank O’Hara. “The Breeders’ Cup” addresses Édouard Manet’s 1865 painting Olympia through ekphrasis, and the painting of a prostitute becomes a patron saint of parody for postmodern poetics. The poem introduces lust as a metaphor for creative …


Geological Controls On Stratigraphy And Sedimentation Of The Mississippian Marshall Formation, Michigan Basin, U.S.A., Joseph G. Adducci Aug 2015

Geological Controls On Stratigraphy And Sedimentation Of The Mississippian Marshall Formation, Michigan Basin, U.S.A., Joseph G. Adducci

Masters Theses

An understanding of regional orogenic, climatic, and eustatic processes is critical to the interbasinal correlation of Paleozoic strata in eastern North America. Tectonic activity associated with the culmination of Appalachian Orogenic events has been shown to have regional influence on paleostructure and sediment dispersal in the Appalachian foreland basin and adjacent intracratonic Illinois and Michigan basins. The culmination of the Acadian Orogeny at the end of the Devonian represents the beginning of a period of general tectonic quiescence extending throughout the early and middle Mississippian in eastern North America. Early Mississippian strata in the Michigan basin is distinctive and marks …


Breastfeeding With The Bronson Mothers’ Milk Bank, Marykate Bodnar Aug 2015

Breastfeeding With The Bronson Mothers’ Milk Bank, Marykate Bodnar

Masters Theses

Bronson Methodist Hospital in Kalamazoo is home to one of only 15 certified breast milk banks in the United States. Women have shared breast milk for centuries through wet nurses, but this institutionalized and regulated version of sharing is distinct from previous forms. Breastfeeding has become a symbol of successful motherhood; donor milk adds a new dimension to this aspect of idealized motherhood. This study explores how the milk bank works: its organizational structure within a hospital, how donors are selected, and how recipients qualify for donor milk. It is grounded in Feminist and Medical Anthropology literature. Using semi-structured interviews …


Assessing High School Science Students’ Abilities To Use Cross Cutting Literacy Skills And Scientific Argumentative Writing Skills In A Mid-Western School District, Ellen M. Karel Aug 2015

Assessing High School Science Students’ Abilities To Use Cross Cutting Literacy Skills And Scientific Argumentative Writing Skills In A Mid-Western School District, Ellen M. Karel

Masters Theses

This study sought to determine to what extent a centrally focused initiative concentrated on how to teach students to not just write, but how to think, read, and speak about real world problems in a persuasive manner based on multiple sets of data related to science concepts, increased scientific argumentative writing proficiencies among high school students. A secondary area this study attempted to explore was the correlation between the implemented processes in the initiative and high school students’ scientific argumentative writing proficiencies. The study was conducted in a mid-western high school, population 1,088, with a select group of students in …


The Experience Of Social Flow In Vocal Jazz Improvisation, Brittany Neuser Aug 2015

The Experience Of Social Flow In Vocal Jazz Improvisation, Brittany Neuser

Masters Theses

The purpose of this study was to evaluate the feasibility of experimental research procedures and gather initial data in studying the experience of social flow within the context of group music production tasks. Participants completed two different group vocal music production tasks: Performance of a pre-composed song and an improvised performance. The Flow State Scale-2 (FSS-2), a 36-item survey in which a mean score of 45 implies the ultimate flow experience and a score of 9 implies that no flow was experienced during the event in question, was used to assess the level of social flow experienced by the participants …


Biogeochemical Alteration Of Particulate Pyrogenic Organic Carbon (Pyc), Jason Matthew Stuart Aug 2015

Biogeochemical Alteration Of Particulate Pyrogenic Organic Carbon (Pyc), Jason Matthew Stuart

Master's Theses

The resistance of plant derived pyrogenic organic carbon (pyC) to abiotic and biotic means of degradation has led to increased interest in the role of pyC as a potential carbon sink, as well as a strategy for sequestering atmospheric CO2 to mitigate excess carbon emissions. Though much research pertaining to the fundamental properties of pyC degradation have been performed in a controlled lab setting, there has been very little work regarding pyC degradation in a field setting where factors such as precipitation and temperature fluctuate seasonally. This work focuses on various degradation characteristics of two …


Ichthyoplankton Composition In The Loop Current And Sargassum Habitats In The Northern Gulf Of Mexico, Stephanie Morgan Taylor Aug 2015

Ichthyoplankton Composition In The Loop Current And Sargassum Habitats In The Northern Gulf Of Mexico, Stephanie Morgan Taylor

Master's Theses

Ichthyoplankton in the Gulf of Mexico (GOM) aggregate in two different habitats that serve to provide refuge and concentrate prey in an otherwise oligotrophic environment: the Loop Current (LC) a mesoscale oceanographic feature characterized by the transition of environmental conditions of the water mass between the GOM and Caribbean; and Sargassum, a two species assemblage of floating brown algae that is habitat for many larval and juvenile obligate and associated fishes. The objectives of this study were to characterize the density and community composition of ichthyoplankton within these habitats using multivariate analysis. I identified three unique assemblages of ichthyoplankton …


An Ethnography Of Taste: Craft Beer Culture In Hattiesburg, Yingkun Hou Aug 2015

An Ethnography Of Taste: Craft Beer Culture In Hattiesburg, Yingkun Hou

Master's Theses

This thesis studies the craft beer culture in Hattiesburg in order to answer the research question: Is taste what draws people to this culture? Beyond conducting classic participant-observation, I deployed the method of sensory activated participant-observation in my fieldwork. In so doing, this research centers the perspective and the data collected on the senses, especially the taste of craft beer. The purpose of this research is to add to our knowledge of the anthropology of the senses and contribute to the literature on the anthropology of taste.


Naturalists’ Perspectives On The Use Of Mobile Technology During A Nature Hike, Aubin Marishka Radzewicz St. Clair Aug 2015

Naturalists’ Perspectives On The Use Of Mobile Technology During A Nature Hike, Aubin Marishka Radzewicz St. Clair

Master's Theses

Naturalists act as our link between scientific knowledge and the public’s understanding of natural history and conservation efforts. In order for them to succeed, they need access to reference materials as well as up-to-date information (Mankin, Warner, & Anderson, 1999). Incorporating mobile technology (i.e. tablets) into naturalists’ endeavors in natural history and environmental education can be used as supportive and educational tools. My project investigated how newly trained naturalists used tablet technology while leading groups of children on nature hikes. I investigated naturalists’ views on the use of mobile technology as a tool during the hikes. My research was guided …


Elucidating The Molecular Function Of Reprolysin Metalloproteases In Tick-Host-Pathogen Interaction, Jaclyn Bo Williams Aug 2015

Elucidating The Molecular Function Of Reprolysin Metalloproteases In Tick-Host-Pathogen Interaction, Jaclyn Bo Williams

Master's Theses

Ticks are ectoparasites that attach to their host for many days to weeks, feeding to engorgement and continuing their species life cycle. The mechanisms behind the successful feeding and manipulation of host immune responses have been associated with the secretion of their specialized saliva. Tick saliva includes a variety of modulatory molecules that must disrupt and counteract defense mechanisms, including a variety of proteases. Reprolysin Metalloproteases, in the Zn2+ dependent family, is secreted as a proenzyme and is shown to have proteolytic activity, degrading fibrinogen and gelatinase activity, as well as disturbing homeostasis12. Previous work with …