Digital Commons Network^™

A Multiple Endpoint Analysis Of The Effects Of Chronic Exposure To Sediment Contaminated With Deepwater Horizon Oil On Juvenile Southern Flounder And Their Associated Microbiomes, Nancy J. Brown-Peterson, Michelle Krasnec, Ryan Takeshita, Caitlin N. Ryan, Kimberly J. Griffitt, Claire Lay, Gregory D. Mayer, Keith M. Bayha, William E. Hawkins, Jeffrey Morris, Robert J. Griffitt

Faculty Publications

Exposure to oiled sediments can negatively impact the health of fish species. Here, we examine the effects of chronic exposure of juvenile southern flounder, Paralichthys lethostigma, to a sediment-oil mixture. Oil:sediment mixtures are persistent over time and can become bioavailable following sediment perturbation or resuspension. Juvenile flounder were exposed for 32 days under controlled laboratory conditions to five concentrations of naturally weathered Macondo MC252 oil mixed into uncontaminated, field-collected sediments. The percent composition of individual polycyclic aromatic hydrocarbons (PAHs) of the weathered oil did not change after mixing with the sediment. Spiked exposure sediments contained 0.04–395 mg/kg tPAH50 (sum of …

Ecotoxicological Risk And Exposure: A Comparison Of Western Burrowing Owls Nesting In Agricultural And Non-Agricultural Areas In The Morley Nelson Snake River Birds Of Prey National Conservation Area, Matthew Stuber

Boise State University Theses and Dissertations

In some portions of their range, western burrowing owls (Athene cunicularia hypugaea) nest in higher densities near irrigated agricultural areas when compared to non-agricultural, arid habitat. Previous research suggests that owls may associate with agricultural areas because of more reliable and abundant prey, particularly invertebrates. One potential cost of this association, however, is an increased risk of exposure of owls to pesticides that are applied to agricultural fields. I investigated the exposure to and possible effects on burrowing owls of organophosphate, organochlorine, and carbamate pesticides in the Morley Nelson Snake River Birds of Prey National Conservation Area (NCA) …

Recreation Disturbance To A Shrub-Steppe Raptor: Biological Consequences, Behavioral Mechanisms, And Management Implications, Robert J. Spaul

Boise State University Theses and Dissertations

With rapid increases in outdoor recreation, and mounting evidence of impacts to wildlife, public land managers and biologists need better information on the nature of this potential disturbance. Outdoor recreation may impact wildlife negatively via human disturbance or habitat degradation. Golden eagles (Aquila chrysaetos) in shrub-steppe habitats face several current and emerging threats, including increased non-motorized and motorized (off-highway vehicle, OHV) recreation. We tested the hypothesis that recreation affects eagle breeding biology by monitoring eagle behavior and reproduction in response to recreation volume and activity types, and landscape features associated with recreation. We also investigated the probability that …

Saliva Cotinine As A Measure Of Abstinence In A Lottery-Based Contingency Management Treatment For Smoking Cessation, Catherine M. Gayman

Dissertations

Contingency management decreases smoking by delivering monetary incentives contingent upon objective verification of abstinence. The present study investigated the effectiveness of monitoring saliva cotinine twice weekly in a contingency-management treatment for cigarette smoking using a cash prize-based payment system. Participants were randomly assigned to either a contingent reinforcement group or a non-contingent reinforcement group. The study began with five consecutive Baseline days during which participants smoked as usual, and was followed by four consecutive Shaping days, during which participants were asked to gradually decrease smoking. During the subsequent three-week Abstinence phase, participants submitted saliva cotinine and breath carbon monoxide samples …

15 Years On Sirna Delivery: Beyond The State-Of-The-Art On Inorganic Nanoparticles For Rnai Therapeutics, Joao Conde, Furong Tian, Alfredo Ambrosone, Yulán Hernandez, Mark Mccully, Catherine C. .Berry, Pedro Baptista, Claudia Tortiglione, Jesus M. De La Fuented

Articles

RNAi has always captivated scientists due to its tremendous power to modulate the phenotype of living organisms. This natural and powerful biological mechanism can now be harnessed to downregulate specific gene expression in diseased cells, opening up endless opportunities. Since most of the conventional siRNA delivery methods are limited by a narrow therapeutic index and significant side and off-target effects, we are now in the dawn of a new age in gene therapy driven by nanotechnology vehicles for RNAi therapeutics. Here, we outlook the “do's and dont's” of the inorganic RNAi nanomaterials developed in the last 15 years and the …

Two Cryptic Species Within Astragalus Cusickii Delimited Using Molecular Phylogenetic Techniques, Jay Christopher Zimmers

Boise State University Theses and Dissertations

Understanding the source of phenotypic variability is a challenge in the biological sciences. Variation in phenotypes is the result of variation in the genetics and environment the organism experiences, but elucidating the relative contribution of these two parameters can pose problems, especially in the field of systematics. Systematists are challenged to classify biological diversity into groups that share common ancestry. Phenotypic variation can be useful to demonstrate common ancestry, but only when the primary contributor to the variation is under strong genetic control, and thus heritable. Cusick’s milkvetch (Astragalus cusickii) is a perennial forb endemic to the intermountain …

A Less-Biased Analysis Of Metalloproteins Reveals Novel Zinc Coordination Geometries, Sen Yao, Robert M. Flight, Eric C. Rouchka, Hunter N. B. Moseley

Molecular and Cellular Biochemistry Faculty Publications

Zinc metalloproteins are involved in many biological processes and play crucial biochemical roles across all domains of life. Local structure around the zinc ion, especially the coordination geometry (CG), is dictated by the protein sequence and is often directly related to the function of the protein. Current methodologies in characterizing zinc metalloproteins' CG consider only previously reported CG models based mainly on nonbiological chemical context. Exceptions to these canonical CG models are either misclassified or discarded as "outliers." Thus, we developed a less-biased method that directly handles potential exceptions without pre-assuming any CG model. Our study shows that numerous exceptions …

Uni Scholarworks Readership Snapshot, August 2015, Bepress

Library Documents & Reports (entire collection)

No abstract provided.

An Analysis Of The Differential Methylation And Expression Of Imprinted Genes In M. M. Musculus, M. M. Domesticus, And Their Hybrids, Anna P. Rice

All NMU Master's Theses

Epigenetics has been found to have an effect on many aspects of biology. Epigenetics refers to modifications of the double-stranded DNA molecule, which do not change the nucleotide sequence but do affect gene expression. DNA methylation is a type of epigenetic modification. Genomic imprinting is a pattern of gene expression that is primarily achieved through DNA methylation, and it results in the expression of only one allele at a particular locus. In this study, I analyzed the methylation patterns of five imprinted genes in the hybrids of two different lab strains of the house mouse subspecies, M. m. musculus and …

Fifty Psychological And Psychiatric Terms To Avoid: A List Of Inaccurate, Misleading, Misused, Ambiguous, And Logically Confused Words And Phrases, Scott O. Lilienfeld, Katheryn C. Sauvigne, Steven J. Lynn, Robin L. Cautin, Robert D. Latzman, Irwin D. Waldman

Psychology Faculty Scholarship

The goal of this article is to promote clear thinking and clear writing among students and teachers of psychological science by curbing terminological misinformation and confusion. To this end, we present a provisional list of 50 commonly used terms in psychology, psychiatry, and allied fields that should be avoided, or at most used sparingly and with explicit caveats. We provide corrective information for students, instructors, and researchers regarding these terms, which we organize for expository purposes into five categories: inaccurate or misleading terms, frequently misused terms, ambiguous terms, oxymorons, and pleonasms. For each term, we (a) explain why it is …

Political Skill Moderates The Success Of Psychopaths At The Workplace, N. Schütte, G. Blickle, R. Frieder, F. Schnitzler, J. Heupel

Management Faculty Publications

On one hand, psychopaths tend to be callous, emotionally deficient, aggressive,
self promoting, impulsive, and pursuant of unmitigated agency regardless of the extent to which it comes at the expense of others. On the other hand, by all accounts, psychopaths tend to be charming, seductive, self-confident, composed, risk-seeking, and adept at impression management (Babiak & Hare, 2006; Paulhus & Williams, 2002). Therefore, the purpose of this study was to reconcile these contrasting positions by examining whether (non-violent) psychopaths truly can be “successful” in the workplace. Drawing on socioanalytic theory (Hogan, 1983), we hypothesized that psychopaths in possession of political skill …

Blended Learning And Bottlenecks In The California State University System: An Empirical Look At The Importance Of Demographic And Performance Analytics, Maureen Augusta Guarcello

Dissertations

In Fall 2014 over 460,000 students enrolled in the 23-campus California State University system; unfortunately, more than 20,000 qualified applicants were denied admission due to capacity and budgetary constraints. In response to continued overcrowding, the Chancellor's Office and Board of Trustees are investigating "bottlenecks," defined as anything limiting students' ability to graduate in a timely manner. Blended learning, a pedagogy combining face-to-face and computer-mediated instruction, presents a potential solution to alleviate overcrowding and bottleneck problems.

In an effort to investigate the extent to which student demographics and performance analytics explain student success outcomes in a popular blended learning psychology course, …

Community Interventions In Kenya Providing Care And Support For Orphaned Girls In High School And College Aged 14-24, Joy Eunice Wambui Mindo

Doctor of Ministry

This is a project manual that looks into the growing problem of orphans in Africa. There is great need to establish community interventions that provide care and support for orphaned girls. Orphan female adolescents experience reduced education opportunities and adaptive coping strategies when they have no home in which to receive nurture and support. They are therefore very vulnerable to early marriages, teenage pregnancies, sexual exploitation and human trafficking. Such women between the ages of fourteen and twenty-four are usually in high school and college, making life long decisions that would affect their future. They go through physical body and …

Pharmacodynamic Assays To Facilitate Preclinical And Clinical Development Of Pre-Mrna Splicing Modulatory Drug Candidates, Yihui Shi, Amanda S. Joyner, William Shadrick, Gustavo Palacios, Chandraiah Lagisetti, Philip M. Potter, Lidia C. Sambucetti, Stefan Stamm, Thomas R. Webb

Molecular and Cellular Biochemistry Faculty Publications

The spliceosome has recently emerged as a new target for cancer chemotherapy and novel antitumor spliceosome targeted agents are under development. Here, we describe two types of novel pharmacodynamic assays that facilitate drug discovery and development of this intriguing class of innovative therapeutics; the first assay is useful for preclinical optimization of small-molecule agents that target the SF3B1 spliceosomal protein in animals, the second assay is an ex vivo validated, gel-based assay for the measurement of drug exposure in human leukocytes. The first assay utilizes a highly specific bioluminescent splicing reporter, based on the skipping of exons 4-11 of a …

Habitat Use By Spruce Grouse In A Fragmented System, Laurel A. Hill

All NMU Master's Theses

The spruce grouse is a boreal obligate species that has been protected in Michigan since 1915 (Ammann 1963). Despite protection, the status of spruce grouse is uncertain in Michigan and other parts of the Midwest, and there have been few attempts at large-scale surveys or monitoring (Williamson et al. 2008). I studied a population of spruce grouse near the southern edge of their range on the Yellow Dog Plains in Marquette County, Michigan.

I investigated fecal pellet counts as a possible method to assess spruce grouse presence and habitat use. My results validated the use of fecal pellet occurrence as …

Caffeine Use Within The Safety Sensitive Industry, Cory Austin Mullins

Theses and Dissertations

This study is an in-depth look at caffeine use and its effect on individuals who work within a safety and security sensitive job industry. The focus of this paper is on the current use of caffeine in our society as well as the overuse/abuse of the drug and the causes behind it. This paper will highlight the negative impacts caffeine has on the human body and its cognitive thinking skills but does not neglect the positive impacts as well. Caffeine in energy drinks and similar products is used in an attempt to retain one’s alertness and focus, with little regard …

Assessment Of Behavior, Home Range, Population Size, And Intermixing Among The Atlantic Bottlenose Dolphin, Tursiops Truncatus, In New Jersey, Colleen Marie Talty

Theses, Dissertations and Culminating Projects

Bottlenose dolphins (Tursiops truncatus) are known to exhibit a range of different social structures and habitat use profiles. To investigate the structure of the population off Cape May, NJ, photo identification techniques were employed. Between April 2013 and November 2014, 209 survey days with 989 individual sightings were observed from a platform of opportunity, the whale watching vessel the American Star. The primary goals of this study were to assess the population size in this area; determine whether or not the inshore ecotype were mixing with the offshore ecotype; determine home range size for dolphins sighted multiple times; and to …

A Visual Analysis Of Articulated Motion Complexity Based On Optical Flow And Spatial-Temporal Features, Beau Michael Christ

School of Computing: Dissertations, Theses, and Student Research

The understanding of motion is an important problem in computer vision with applications including crowd-flow analysis, video surveillance, and estimating three-dimensional structure. A less-explored problem is the visual characterization and quantification of motion complexity. An important motion class that is prevalent in living beings is articulated motion (segments connected by joints). At present, no known standardized measure for quantifying the complexity of articulated motion exists. Such a measure could facilitate advanced motion analysis with applications including video indexing, motion comparison, and advanced biological study of visual signals in organisms.

This dissertation presents an in-depth study of the development of several …

Cultural Dimensions: A Comparative Analysis Of Aviation Students In China And The U.S., Julius Keller, Yu Wang, Jacqueline Cooney, Anthony Erstad, Chientsung Lu

International Journal of Aviation, Aeronautics, and Aerospace

Research has shown cultural dimensions can provide insight into effective management within diverse work and school environments. (Sandal & Manzey, 2009). In this study, researchers distributed a research questionnaire based on Hofstede’s original four cultural dimensions: power distance, masculinity vs femininity, uncertainty avoidance and individualism vs collectivism. Participants were recruited from two collegiate aviation programs, one in China and the other in the United States.

Independent t-tests were used to compare mean cultural dimensions scores for the groups. Study findings suggested significant differences between the two groups for the cultural dimensions: power distance, masculinity vs femininity and individualism vs …

Evaluation Of An Abbreviated Parent-Child Interaction Therapy Intervention In A Pediatric Primary Care Setting, Colleen C. Cullinan

Dissertations

Pediatric primary care providers encounter a substantial number of behavioral health concerns during routine visits. These providers are in a unique position to screen for and identify psychosocial difficulties, offer anticipatory guidance, and provide brief mental health interventions to families. Unfortunately, many pediatricians face barriers in screening for behavioral problems and providing appropriate interventions, particularly regarding externalizing behavior problems. Providing integrated behavioral health services in the primary care setting can reduce barriers to treatment, the stigma associated with mental health settings, and the cost of services (Berkout & Gross, 2013). There is increasing interest in adapting parent training programs for …

Novel Stretchable Printed Wearable Sensor For Monitoring Body Movement, Temperature And Electrocardiogram, Along With The Readout Circuit, Ali Eshkeiti

Dissertations

Conformal and stretchable wearable sensors provide vital real time information about individual’s health conditions. In this work, Traditional printing methods are used for fabrication of stretchable and wearable sensors which can be mounted on the human skin for the purpose of health tracking. In addition, screen printing technology was utilized to develop printed and flexible electronic circuit board which can be used as a readout circuit along with fabricated wearable sensors. The dissertation is organized and pursued in three projects.

In the first project, screen printing was used to fabricate multi-layer PCBs using printed deposited materials on three distinct substrates. …

Assessing The Interpersonal Effectiveness Of The Dear-Man Skill Using A Social Psychology Paradigm, Matthew T. Jameson

Dissertations

For more than 50 years, social psychology has investigated persuasion techniques intended to facilitate influencing the behavior of others. This body of research has identified a variety of effective techniques and principles (see Cialdini, 2007). Over roughly the same period, clinical psychologists developed interventions targeting assertiveness, the ability to influence others in socially appropriate ways (see Long, Long, & Whitson, 2009) and the related construct “interpersonal effectiveness,” the ability to influence others without harming relationships or self-respect (Linehan, 2015, pp. 231-237). A literature review conducted by the author was unable to identify linkages between these two related areas of inquiry. …

Investigations Of Filarial Nematode Motility, Response To Drug Treatment, And Pathology, Charles Nutting

Dissertations

More than a billion people live at risk of chronic diseases caused by parasitic filarial nematodes. These diseases: lymphatic filariasis, onchocerciasis, and loaisis cause significant morbidity, degrading the health, quality of life, and economic productivity of those who suffer from them. Though treatable, there is no cure to rid those infected of adult parasites. The parasites can modulate the immune system and live for 10-15 years. Testing of compounds against filarial nematodes is complicated due to a lack of an objective platform on which to analyze in vitro treatments. There is no published, immunocompetent laboratory model for lymphatic filariasis. This …

Ultrafast Charge Carrier Dynamics In Bare And Surface-Modified Semiconductor Nanoparticles, Jameel Abdul-Hadi Hasan

Dissertations

Charge-carrier relaxation dynamics in semiconductor nanoparticles has been in the forefront of research for last three decades both for their fundamental nature as well as for applications in light-harvesting, luminescent labels, light-emitting diodes and nonlinear optics. Significant research has focused on II-VI semiconductors with emphasis on CdS and CdSe that are toxic. On the other hand, ZnO and TiO2 semiconductor nanoparticles are less toxic and have enormous applications in photo-catalysis, water splitting, solar cells and optical sensors. However, the investigations of charge-carrier dynamics in these semiconductor nanomaterials compared to II-VI semiconductor quantum dots are quite limited. The knowledge of charge-carrier …

Behavior Analysis Program To Improve Habits Of Physical Activity, Eating, And Sleeping, Ivan Noe Martinez Salazar

Dissertations

An Internet-based five-week duration program to improve “health habits” using behavior analysis principles and eHealth technology was developed and evaluated. The “health habits” include recurring behaviors that impact health status such as eating, sleeping, and physical activity.

Ten adult participants were recruited online from Mexico. A multiple baseline design was used and participants were randomly assigned into two different groups (i.e., ABBAA and AABBA groups). Participants received online training using videos describing the characteristics of the program and its components. Each participant recorded selected health behaviors using a Microsoft Excel® tool designed specifically for this program’s goal achievements. Participants reported …

Single-Gender Educational Environments Serving African American Males: A Strategy For Closing The Achievement Gap, Angela P. Green

Education Doctoral

Student achievement data reveal that a disproportionate number of African American males are failing in school, placed in special-education classes, suspended or expelled from school, or incarcerated. Males of color factor substantially in the analysis of the achievement gap and its impact on economic and social development. The purpose of this quantitative study was to investigate whether single-gender environments had a significant impact on the academic performance of African American males in a public, urban middle school. The application of several theories guided this work: The African American male theory, ecological systems theory, critical race theory, and oppositional culture theory. …

Teacher Attitudes Toward Collaboration In An Independent Elementary School To Improve Instructional Practice, Stephanie A. Royal

Education Doctoral

Research has confirmed that teachers who work collaboratively have the opportunity to exchange ideas and instructional methods to enhance their performance in the classroom. Using this as a guiding premise, the purpose of this study was to better understand teacher attitudes toward collaboration in an independent school setting. The study examined the complexities of collaboration in an effort to make a connection between collaboration among teachers and teacher learning. The study sought to identify the conditions that support opportunities for collaboration employing the definition and framework for a professional learning community. The setting for the study was a K-8 independent …

Lived Experiences Of Belonging To Multiple Nationalities, Annette Susanne Peters

Dissertations

No abstract provided.

Scarnas Regulate Splicing And Vertebrate Heart Development., Prakash Patil, Nataliya Kibiryeva, Tamayo Uechi, Jennifer A. Marshall, James E. O'Brien, Michael Artman, Naoya Kenmochi, Douglas C. Bittel

Manuscripts, Articles, Book Chapters and Other Papers

Alternative splicing (AS) plays an important role in regulating mammalian heart development, but a link between misregulated splicing and congenital heart defects (CHDs) has not been shown. We reported that more than 50% of genes associated with heart development were alternatively spliced in the right ventricle (RV) of infants with tetralogy of Fallot (TOF). Moreover, there was a significant decrease in the level of 12 small cajal body-specific RNAs (scaRNAs) that direct the biochemical modification of specific nucleotides in spliceosomal RNAs. We sought to determine if scaRNA levels influence patterns of AS and heart development. We used primary cells derived …

Soil Erosion In Humid Regions: A Review, Daniel J. Holz, Karl W.J. Williard, Pamela J. Edwards, Jon E. Schoonover

Journal of Contemporary Water Research and Education

Soil erosion has significant implications for land productivity and surface water quality, as sediment is the leading water pollutant worldwide. Here, erosion processes are defined. The dominant factors influencing soil erosion in humid areas are reviewed, with an emphasis on the roles of precipitation, soil moisture, soil porosity, slope steepness and length, vegetation, and soil organisms. Erosion dynamics in forested watersheds are the focus with some examples from agricultural watersheds included as well. Lastly, best management practices for controlling surface erosion are discussed.