Digital Commons Network^™

The International Glossary On Infertility And Fertility Care, 2025†., Fernando Zegers-Hochschild, Silke Dyer, G David Adamson, Valerie Baker, Kurt Barnhart, Siladitya Bhattacharya, Clare Boothroyd, Georgina Chambers, Jacques De Mouzon, Eman Elgindy, Bart Fauser, Karin Hammarberg, Marcos Horton, Osamu Ishihara, Seung Chik Jwa, Mohamed Khrouf, Markus Kupka, Dolores J. Lamb, Martha Luna, A Gustavo Martinez, Brent Monseur, Peter Nagy, Anja Pinborg, Catherine Racowsky, Laura Rienzi, Peter Schlegel, Lone Schmidt, Lan Ngoc Vuong, Tari Turner, Mónica Hebe Vázquez-Levin, Ibrahim Wada, Dagan Wells, Christine Wyns

Manuscripts, Articles, Book Chapters and Other Papers

STUDY QUESTION: What updates of the International Glossary on Infertility and Fertility Care are required, to reflect contemporary scientific knowledge, social needs, and inclusive definitions, while harmonizing international communication across clinical, research, policy, and public domains?

SUMMARY ANSWER: This 4th edition presents 348 consensus-based terms and definitions, including numerous revisions from the previous edition and 79 newly introduced definitions reflecting advances in reproductive science, technology, and evolving social contexts.

WHAT IS KNOWN ALREADY: Previous glossary editions (2006, 2009, 2017) established internationally recognized definitions related to clinical practice, research, and policy. The 2017 edition comprised 283 terms and, among many others, …

Severe Thiopurine-Induced Myelosuppression In A Pediatric Acute Lymphoblastic Leukemia Patient With The Nudt15 *1/*6 Genotype: A Brief Report., Jillian Fry, Erin C. Boone, Wendy Y. Wang, Shobana John, Lisa A. Lansdon, Midhat S. Farooqi, Byunggil Yoo, Andrea Gaedigk, Keith August, Terrie Flatt, Laura Ramsey

Manuscripts, Articles, Book Chapters and Other Papers

Variants in TPMT and NUDT15 genes that affect thiopurine metabolism can guide personalized dosing to minimize toxicity. Decreased or no appreciable NUDT15 activity demonstrates impaired breakdown of active thiopurine metabolites which can lead to severe adverse events including potentially life-threatening myelosuppression. Recently, the NUDT15*6 allele was re-classified from having uncertain function to no function by the Clinical Pharmacogenetics Implementation Consortium. Here, we present a pediatric patient with a NUDT15*1/*6 genotype who experienced significant thiopurine-induced myelosuppression. The patient is a 4-year-old female with standard risk-average precursor B-cell acute lymphoblastic leukemia treated per AALL1731. Exome sequencing determined TPMT*1/*1 (normal metabolizer) and NUDT15*1/*6 …

Computational Modeling To Evaluate Bipolar Flexible Electrode Designs For Use In Sciatic Nerve Stimulation, Krystyna S. Allman

Master's Theses

Peripheral nerve stimulation is clinically used to manage pain, rehabilitate motor function, and promote nerve regeneration. The sciatic nerve is often studied for stimulation due to its accessibility and clinical relevance. A conventional nerve cuff electrode is the least invasive method for nerve stimulation, but the mismatch of mechanical properties of the electrode with the nerve tissue can cause damage to the nerve and the electrode itself. This study investigated a novel bipolar, gold nanowire-based cuff electrode design and its ability to selectively activate fibers in the rat sciatic nerve at varying interelectrode spacings. In COMSOL, A finite element model …

Thermodynamics Of Binding Between Adeno-Associated Viruses And Heparin In Bulk And At Interfaces Via Isothermal Titration Calorimetry, Elizabeth Adeogun, Jude C. Obijiaku, Ronny Horax, Kayla E. Daugherty, Joshua Sakon, Xianghong Qian, Barbara Knutson, Stephen E. Rankin, Karthik Nayani

Chemical and Materials Engineering Faculty Publications

Adeno-associated viruses (AAVs) have emerged as promising vectors for gene therapy due to their non-pathogenic nature and ability to transduce various cell types efficiently. In recent years, there has been an increasing effort to optimize the production and purification of AAV to support clinical applications; however, challenges exist in affinity ligand design, synthesis, and characterization. Understanding the binding interactions of these viruses with functional molecules is pivotal for the development of affinity-based separation methods of AAVs. Classical methods to measure thermodynamic parameters such as Isothermal Titration Calorimetry (ITC) are challenging to employ in these scenarios, as the concentrations of the …

Ecological Support For Stem International Doctoral Student Success, Emily A. Crider

Journal of Comparative & International Higher Education

International doctoral students enrich U.S. institutions but often encounter challenges that affect belonging and academic success. This qualitative study examined the social, cultural, and institutional challenges faced by international STEM doctoral students and the role of faculty advisor relationships in their adaptation. Guided by ecological systems theory, interviews with eight participants revealed five major challenges: language barriers, cultural differences, building social networks, financial challenges, and navigating institutional processes. Positive faculty mentorship was critical, with effective advisors demonstrating empathy, adaptability, responsiveness, guidance, and trust while supporting professional development, funding, and networking. Microsystem and mesosystem interactions were most influential. Findings emphasize the …

Use Of Function Diagrams In Physiology Education, Thad E. Wilson, Brian A. Jackson, B. Peter Sawaya

Physiology Faculty Publications

Function diagrams focus on physiological concepts rather than associated structures and can serve as elaboration tools and mnemonic aids. A function diagram prototype of the gastrointestinal system was recently described (Wilson TE, Barrett KE. Adv Physiol Educ 45: 264-268, 2021). In this article, a functional diagram of the glomerulus, nephron, urinary system, and bladder is proposed. Colloquially named "Nessie the Nephron" to loosely capture the looping structure and elusive understanding of renal blood flow, glomerular filtration, and epithelial transport for the student, not to mention the nearly mythical countercurrent multiplier. "Navigating the Lochs" references Nessie's possible habitat and more importantly …

Fire–Climate–Vegetation Linkages In A Quaking Aspen Forest During The Late Holocene, R. Justin Derose, Jesse L. Morris

Wildland Resources Faculty Publications

Fire plays an important role in shaping forested ecosystems around the globe. Unlike many other fire-driven forest types, our understanding of pre-settlement fire behavior in quaking aspen (Populus tremuloides) systems is limited. To better understand the frequency and severity of fires in a putatively stable quaking aspen forest, a small, key watershed was selected for sediment coring to reconstruct fire history, vegetation change, and climatic variability. The study aim was to explore the fire–climate–vegetation linkages in an aspen-dominated catchment. For the past ~4000 years this basin has been dominated by quaking aspen but also subalpine fir (Abies …

Thermosiphon Lab Experiment, Ella C. Perry, Zach Barry, Madison K. Felton, Lane A. Hunter

Mechanical Engineering

The Cal Poly Mechanical Engineering Department aims to develop a new lab centered on a thermosiphon solar system. This lab will introduce the operating principles of thermosiphons while integrating concepts from heat transfer, fluid dynamics, and thermodynamics. A thermosiphon functions by heating water using thermal energy. The lab will examine the efficiency of this energy transfer. The final lab will be tailored to enhance student learning while ensuring ease of use for the Mechanical Engineering Department.

Finishing Location Influences The Color Stability Of Steaks From Grass-Finished Bison Bulls, Garrett Weldy, Christina Bakker, Judson Grubbs, Keith Underwood, Carter Kruse, Ana Paula Salim, Surendranath Suman, Amanda Blair

Animal Science Research Report 2026

No abstract provided.

Observing Ph Of Grass-Fed Bison Heifer Gastrointestinal Tracts Postmortem, Ekaterina Lopez-Bondarchuk, Madison Higbee, Kallen Kafka, Ava Graham, Phillip Urso

Animal Science Research Report 2026

No abstract provided.

Hydropower Collegiate Competition 2026, Andres R. Arreola, Sammy D. Taporco, Kathryn E. Tinney, Ahmer S. Dhillon

Mechanical Engineering

The Hydropower Collegiate Competition (HCC) is sponsored by the Department of Energy’s (DOE) Water Power Technologies Office (WPTO) and is meant to offer university students an opportunity to solve complex hydropower challenges, build industry connections, explore career connections, and obtain a greater knowledge of hydropower’s potential in the United States. For this year’s competition, our team investigated a potential in-conduit hydropower site in California. Our work included creating a design package for a crossflow turbine related to our selected site and completing the community connections challenge. We also completed a siting and design report, community connections report, design and siting …

University Of Nebraska At Omaha Division Of Biomechanics And Research Development Annual Report 2023-2025, Uno Biomechanics

Biomechanics Annual Report

This report contains:

A letter from the Director: Dr. Nick Stergiou

Highlights articles

Center for Cardiovascular Research in Biomechanics (CRiB) articles

The Center for Research in Human Movement Variability (MOVCENTR) articles

People of UNO Biomechanics

Student Centered articles

Education Initiative articles

A Phenomenological Study Of The Lived Experiences Of Vicarious Trauma And Emotional And Somatic Resource Replenishment Among K-12 School Principals In Suburban Communities, Rachael A. Garcia

Education Doctoral

This qualitative study, grounded in the job demands-resources (JD-R) theory, explores the lived experiences of K-12 principals in suburban communities as they encounter vicarious trauma (VT). The study aims to fill a gap in the research by examining how these leaders deliberately employ strategies to replenish their emotional and somatic resources and develop resilience. The role of school principals has evolved significantly, now requiring them to provide substantial social-emotional support for both students and staff, which exposes them to others' traumatic experiences. This exposure can lead to vicarious trauma, a deep psychological transformation resulting in emotional exhaustion, compassion fatigue, and …

U.S. Regulation And Litigation Regarding Gmos: A Cautionary Tale Of A Piecemeal Framework, Michael R. Reese, George V. Granade

Northern Illinois University Law Review

Bioengineered crops using genetically modified organisms (GMOs or GM) are big business in the United States. In little more than two decades, GM agriculture constitutes more than 90% of crops such as corn, soy, and canola. The acceptance of GMO foods by consumers, however, has not been as robust—leading to demand for labeling regulations so consumers can identify whether their foods contain GMOs. U.S. law governing GMOs, particularly food labeling, lacks a comprehensive regulatory scheme and is instead highly fragmented. The Food and Drug Administration (FDA) has debated how to label such foods for over a decade, issuing no rules …

Bringing The Museum To The Library: A Collaboration Between A Natural History Museum And An Academic Science Library, Angela D. Price, Jean Bossart

Collaborative Librarianship

A persistent challenge on college campuses is effectively connecting students with the wide array of university resources available to them. At the University of Florida, an opportunity to address this challenge emerged when the Florida Museum of Natural History (FLMNH), a major campus institution with extensive scientific collections, was scheduled for a 15-month closure due to renovations. In response, librarians at the Marston Science Library initiated a collaborative partnership with FLMNH, offering the library as a venue for science-related events and programming. This collaboration enhanced student engagement, added a non-traditional venue for science learning and interaction, and proved mutually beneficial …

Roots And Greens: Discovering The Power Of Indigenous Produce, Abiodun T. Atoloye, Sherif O. Olasoji, Ebunoluwa G. Ibidapo

Nutrition, Dietetics, and Food Sciences Courseware

The curriculum was designed in alignment with the Cognitive Theory of Multimedia Learning (CTML), Empowerment Theory (ET), and Social Cognitive Theory (SCT) frameworks. These frameworks were used to determine the selection and sequencing of learning activities. As reflected in CTML principles, the use of texts, images, infographics, and videos enhances knowledge retention and information comprehension and helps prevent cognitive overload. Through activities, homework, and family engagement, the principles of ET were incorporated into the curriculum to facilitate participants’ perceived control over food-related decisions. Additionally, by applying the principles of SCT, the curriculum incorporates scenario-based questions, opportunities to engage with peers, …

Comparable Endogenous Immune Reconstitution, Car-T Expansion, And Cytokine Profiles With Bendamustine Versus Fludarabine/Cyclophosphamide Lymphodepletion, Matthew Schwede, Sarah Hawley, Zachary Reitz, Faith Kierney, Neil Bailey, Tenzin Tsomo, Laiken Lopez, Terry Gilbertson, Christopher A Carney, Doug Kieper, Kelly Paulson, Krish Patel

All Poster Presentations

No abstract provided.

From Lineage Discovery To Conservation Prioritisation, Zachary G. Macdonald, Joscha Beninde, Julian R. Dupuis, Thomas W. Gillespie, H. Bradley Shaffer, Gregory F. Grether

Entomology Faculty Publications

Accurate inferences of diversification and evolutionary processes depend on knowing how many independently evolving lineages exist within nominally widespread taxa. Uncertainty in lineage number and composition also limits our ability to meaningfully prioritise conservation efforts. Addressing these knowledge gaps requires frameworks that sequentially identify distinct lineages, assess mechanisms that contribute to their divergence, and quantify spatial and environmental determinants of their genomic diversity. With these goals in mind, we apply whole-genome, ecological, and morphological analyses to the American rubyspot damselfly (Hetaerina americana), a widespread and well-studied North American insect that has been long regarded as a single species of least …

Contextual Variability In Under-Diagnosed Cardiometabolic Disease And Cognitive Vulnerability Among Populations At High Risk For Alzheimer's Disease And Related Dementias, Nwanyieze Jiakponnah, Joseph Curran, Tamlyn Watermeyer, Jasmit Shah, Litha Musili, Stanely Onyango, Benard Aliwa, Zul Merali, Karen Blackmon, Chinedu Momoh

Brain and Mind Institute

Underdiagnosis of cardiometabolic risk factors (CMRFs) may represent an unrecognised biological pathway contributing to dementia risk; yet remains poorly characterised in African and African diaspora populations. We quantified the prevalence and determinants of underdiagnosed hypertension and abnormal glycaemia across four cohorts comprising up to 7000 adults aged ≥40 years from Nigeria, Kenya, and The United States: Indianapolis, and North Texas. Underdiagnosis was defined as absence of self-reported diagnosis despite elevated systolic blood pressure ( ≥130 mmHg) or fasting blood glucose ( ≥100 mg/dL). Cohort-stratified analyses examined demographic, socioeconomic, cognitive, Alzheimer’s genetic, and blood-based biomarker correlates. Underdiagnosis was pervasive in African …

Navigating Precarity: Resourcefulness And Interdependence In The Upper Valley Dairy Industry, Benna Mcdermott

Geography Undergraduate Senior Theses

No abstract provided.

Informal Humans? Rights To A Clean Environment In Bangkok’S Informal Settlements, Maisie Pike

Geography Undergraduate Senior Theses

No abstract provided.

Adhesion Index Integrates Cell And Bacterial Responses To Titanium Across Protein Conditioning And Surface Roughness, Sahar Afshari, James D. Boyd, Victoria L. Stanton, Arnold Stromberg, Katherine L. Thompson, David M. Devito, Craig S. Miller, Martha E. Grady

Mechanical Engineering Faculty Publications

Biofilm formation is a primary cause of implant-associated infections in dental and orthopedic devices. Early interactions between bacteria and host cells at the implant surface critically influence subsequent infection or successful integration. Therefore, biocompatibility screening should evaluate both biofilm formation and cell adhesion. Adhesion Index, defined as the ratio of cell adhesion to biofilm adhesion, provides a non-dimensional number to optimize towards that end. In this work, the laser spallation technique is implemented to compare the effects of implant surface characteristics (rough and smooth titanium) and protein coatings (blood plasma and fibronectin) on bacterial biofilm (Streptococcus mutans, Staphylococcus aureus) and …

Comparable Endogenous Immune Reconstitution, Car-T Expansion, And Cytokine Profiles With Bendamustine Versus Fludarabine/Cyclophosphamide Lymphodepletion, Matthew Schwede

All Podium Presentations

No abstract provided.

Impact Of Gum Chewing On Postoperative Ileus Following Open Heart Surgery At Swedish Cherry Hill, Jacinta Smith

All Podium Presentations

No abstract provided.

Xenaforms: Reinforcing Kinematic Stability Through Rigid Connections, Katherine G. Thies

Architectural Engineering

XenaForms combine rigid planes and straight lines with the fluidity of structural origami to create beautiful, organic folded plate structures. Unlike many conventional structures, folded plate systems derive their stability from the interaction between connected panels, creating the appearance of a single continuous sheet of material. The XenaForm uses structural origami and triangulation to create stable points at the apex of two non-colinear triangles. While it is mathematically true that no moment needs to be transferred across the seam between panels in order to have a stable structure, allowing some moment capacity greatly helps during construction. Specifically, these stiff connections …

Alara+: Summit On Radiation And Orthopedic Risks In Fluoroscopic Laboratories: Endorsed By Acc, Acvp, Ase, Hrs, Scai, Sir, Snis, Svin, And Svs, Arash Salavitabar, Amit N. Vora, Dorothea Altschul, J. Fritz Angle, Chelsea Ballinger, Andrew Bojanowski, Anna E. Bortnick, Kyle Bugg, Emily Carpenter, Robert E. Foster, Joanna Ghobrial, Matthew Glogoza, Atul Gupta, James B. Hermiller, A. Kyle Jones, Summer L. Kaplan, Steven J. Kraus, Omar Khalique, Andrea Klein, Nick Morse, Preethi Ramchand, David G. Rizik, Lucy M. Safi, Cheryl C. Schultz, Kamala P. Tamirisa, R. Jay Widmer, Kristi Wilson, Jonathan X. Fang, Arnold Seto, Robert F. Riley

Department of Neurosurgery Faculty Papers

Occupational radiation exposure has a clear association with long-term health effects and has a particular impact on women, trainees, and supporting staff. There is a reliance on limited, traditional radiation protection and nonergonomic equipment, which carries associated orthopedic injury rates with adverse impacts on both individual career trajectories and health systems, and with significant challenges to widespread implementation of enhanced radiation protection devices. During the 2025 Society for Cardiovascular Angiography & Interventions Scientific Sessions in Washington, DC, a multidisciplinary Think Tank summit was convened and included representatives from multiple stakeholders, including other professional societies, advocacy groups, and industry partners. The …

Viruses Causing Panleukopenia In Domestic Cats: A Review Of Feline And Canine Parvoviruses, Simon Colby

University Honors Theses

Parvoviruses remain among the most important viral pathogens in domestic cats today. Despite this, there is much confusion around which parvoviruses can infect cats, and what extent of disease they can cause. One of the two parvoviruses infecting cats, canine parvovirus type-2 (CPV-2), likely evolved from the other parvovirus infecting cats, feline parvovirus (FPV). These viruses differ at only a few places in their genomes, and share the method of cell entry via the transferrin receptor. The disease caused by FPV has been well characterized in cats, but disease caused by CPV-2 is more obscure. Additionally, current testing methods for …

Interrupted By Design: The Impact Of Push Notifications On Stress And Task Performance, Mia Hohmann

University Honors Theses

As digital communication becomes unavoidable at work, notifications have become one of the most common and overlooked sources of interruption. Drawing from current technostress literature, this study investigates how notifications impact acute and perceived stress as well as task speed and accuracy. In an experimental setting, employed university students (N = 35) completed a data-entry task while receiving either no notifications, task-relevant notifications or task-irrelevant notifications to examine how different types of digital interruptions influenced stress and performance. Stress was measured through a pre- and post-task survey and performance was assessed through both speed and accuracy. Although results showed significant …

The Dolor: How A Generation Of Women Quietly Lost Their Children, Alexis Mclean

University Honors Theses

This thesis is an exploration of the phenomenon of increased adoption rates between the years of 1945 and 1973 and attempts to establish a cohesive explanation for and image of the experience of these birth mothers. My research found that adoptions during this time period are generally characterized by the utilization of maternity homes, coercion, and secrecy. The typical birth mother during this time was white and middle class, emblematic of the motivations of their adoptions: to maintain an idealist image of their motherhood and maintain socioeconomic status. Despite this position framed by privilege, these women too often report having …

Developing A High-Resolution Off-Axis Common-Mode Digital Holographic Microscope, Lucy Cook

University Honors Theses

Off-axis digital holographic microscopy (DHM) is a powerful tool for 3D, non-invasive live-cell tracking without moving parts. However, traditional setups face an inherent dilemma: split-path interferometers offer high spatial resolution but poor temporal stability, while more stable common-mode configurations are historically limited to lower numerical aperture (NA) regimes. This thesis bridges that gap by scaling a common-mode DHM architecture into a high-resolution benchtop instrument featuring NA = 0.65 objectives, paired with a high-power 520 nm laser source to combat transmission losses and sustain imaging frame rates across an expanded optical footprint. We map the multi-variable design space required to satisfy …