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2015

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Hedgehog Signaling In Cancer, Jun Long Aug 2015

Hedgehog Signaling In Cancer, Jun Long

Open Access Dissertations

Two major biological questions regarding Hedgehog (HH) signaling were investigated in this dissertation. The first important question is the role of lipid modification in HH ligand function, while the second one is epigenetic regulation in HH-driven cancer. In the second chapter, identification of lipid modifications in HH ligands from different contexts and pertinent functional studies were performed to elaborate the role of lipids in regulating the biological properties of HH. This is the first description of heterogeneous fatty acylation in a fully processed form of HH ligand, and shows that such a profile of lipidation is dynamic in different cellular …

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Nutrient Dynamics In The Coral-Algal Symbiosis: Developing Insight From Biogeochemical Techniques, Quinn B. Devlin Aug 2015

Nutrient Dynamics In The Coral-Algal Symbiosis: Developing Insight From Biogeochemical Techniques, Quinn B. Devlin

Open Access Dissertations

This work addresses the threats of nitrogen loading to coral reefs and encompasses many unanswered questions on the topic of dissolved inorganic (DIN) utilization by Scleractinian corals and their endosymbiotic algae. Experimental efforts were made to understand the conditions under which NO3- or NH4+ leads to declines in calcification and identify other physiological changes in the coral-algal symbiosis which may accompany such growth declines. The synergistic influences of NH4+ and CO2 were investigated in order to gain insight on the potential influences of elevated DIN on corals in a high CO2 world. The study of NO3- and NH4+ uptake and …

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Summer 2015 Commencement - The University Of Texas Of The Permian Basin, The University Of Texas Permian Basin Aug 2015

Summer 2015 Commencement - The University Of Texas Of The Permian Basin, The University Of Texas Permian Basin

UTPB Commencement Programs

Summer 2015 Commencement - August 7, 2015

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Comparison Of Ch∙∙O, Sh∙∙O, Chalcogen, And Tetrel Bonds Formed By Neutral And Cationic Sulfur-Containing Compounds, Steve Scheiner Aug 2015

Comparison Of Ch∙∙O, Sh∙∙O, Chalcogen, And Tetrel Bonds Formed By Neutral And Cationic Sulfur-Containing Compounds, Steve Scheiner

Chemistry and Biochemistry Faculty Publications

The ability of neutral and charged S-compounds to form different sorts of noncovalent bonds is examined by ab initio calculations. Neutrals are represented by CH3SH and fluoro substituted FSCH3; cations are (CH3)3S+, CH3SH2+, and FHSCH3+. Each is paired with N-methylacetamide (NMA) whose O atom serves as common electron donor. Charged species engage in much stronger noncovalent bonds than do the neutral molecules, by as much as an order of magnitude. The strongest noncovalent bond for any system is a O∙∙SF chalcogen bond wherein the O lies directly opposite a S-F covalent bond, amounting to as much as 39 kcal/mol. Second …

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Antileukemic Efficacy Of Continuous Vs Discontinuous Dexamethasone In Murine Models Of Acute Lymphoblastic Leukemia, L B. Ramsey, L J. Janke, M A. Payton, X Cai, S W. Paugh, S E. Karol, Landry K. Kamdem, C Cheng, R T. Williams, S Jeha, C H. Pui, W E. Evans, M V. Relling Aug 2015

Antileukemic Efficacy Of Continuous Vs Discontinuous Dexamethasone In Murine Models Of Acute Lymphoblastic Leukemia, L B. Ramsey, L J. Janke, M A. Payton, X Cai, S W. Paugh, S E. Karol, Landry K. Kamdem, C Cheng, R T. Williams, S Jeha, C H. Pui, W E. Evans, M V. Relling

Faculty Research ​and Publications

Osteonecrosis is one of the most common, serious, toxicities resulting from the treatment of acute lymphoblastic leukemia. In recent years, pediatric acute lymphoblastic leukemia clinical trials have used discontinuous rather than continuous dosing of dexamethasone in an effort to reduce the incidence of osteonecrosis. However, it is not known whether discontinuous dosing would compromise antileukemic efficacy of glucocorticoids. Therefore, we tested the efficacy of discontinuous dexamethasone against continuous dexamethasone in murine models bearing human acute lymphoblastic leukemia xenografts (n = 8 patient samples) or murine BCR-ABL+ acute lymphoblastic leukemia. Plasma dexamethasone concentrations (7.9 to 212 nM) were similar to those …

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Summer Commencement: August 7, 2015, University Of North Dakota Aug 2015

Summer Commencement: August 7, 2015, University Of North Dakota

UND Commencement Programs

UND Summer Commencement program from August 7, 2015.

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2015-August-07-Avery Shell, University Marketing And Communications, East Tennessee State University Aug 2015

2015-August-07-Avery Shell, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

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2015-August-07-Avery Shell, University Marketing And Communications, East Tennessee State University Aug 2015

2015-August-07-Avery Shell, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

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Pervasive And Strong Effects Of Plants On Soil Chemistry: A Meta-Analysis Of Individual Plant ‘Zinke’ Effects, Bonnie G. Waring, Leonor Álvarez-Cansino, Kathryn E. Barry, Kristen K. Becklund, Sarah Dale, Maria G. Gei, Adrienne B. Keller, Omar R. Lopez, Lars Markesteijn, Scott A. Mangan, Charlotte E. Riggs, Maria Elizabeth Rodríguez-Ronderos, R. Max Segnitz, Stefan A. Schnitzer, Jennifer S. Powers Aug 2015

Pervasive And Strong Effects Of Plants On Soil Chemistry: A Meta-Analysis Of Individual Plant ‘Zinke’ Effects, Bonnie G. Waring, Leonor Álvarez-Cansino, Kathryn E. Barry, Kristen K. Becklund, Sarah Dale, Maria G. Gei, Adrienne B. Keller, Omar R. Lopez, Lars Markesteijn, Scott A. Mangan, Charlotte E. Riggs, Maria Elizabeth Rodríguez-Ronderos, R. Max Segnitz, Stefan A. Schnitzer, Jennifer S. Powers

Biological Sciences Faculty Research and Publications

Plant species leave a chemical signature in the soils below them, generating fine-scale spatial variation that drives ecological processes. Since the publication of a seminal paper on plant-mediated soil heterogeneity by Paul Zinke in 1962, a robust literature has developed examining effects of individual plants on their local environments (individual plant effects). Here, we synthesize this work using meta-analysis to show that plant effects are strong and pervasive across ecosystems on six continents. Overall, soil properties beneath individual plants differ from those of neighbours by an average of 41%. Although the magnitudes of individual plant effects exhibit weak relationships with …

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Evidence For The Involvement Of Sphingosine-1-Phosphate In The Homing And Engraftment Of Hematopoietic Stem Cells To Bone Marrow, Mateusz Adamiak, Sylwia Borkowska, Marcin Wysoczynski, Malwina Suszynska, Magda Kucia, Gregg Rokosh, Ahmed Abdel-Latif, Janina Ratajczak, Mariusz Z. Ratajczak Aug 2015

Evidence For The Involvement Of Sphingosine-1-Phosphate In The Homing And Engraftment Of Hematopoietic Stem Cells To Bone Marrow, Mateusz Adamiak, Sylwia Borkowska, Marcin Wysoczynski, Malwina Suszynska, Magda Kucia, Gregg Rokosh, Ahmed Abdel-Latif, Janina Ratajczak, Mariusz Z. Ratajczak

Internal Medicine Faculty Publications

The α-chemokine stromal-derived factor 1 (SDF-1), which binds to the CXCR4 receptor, directs migration and homing of CXCR4+ hematopoietic stem/progenitor cells (HSPCs) to bone marrow (BM) stem cell niches. Nevertheless, it is also known that CXCR4-/- fetal liver-derived hematopoietic stem cells engraft into BM and that blockade of CXCR4 by its antagonist AMD3100 does not prevent engraftment of HSPCs. Because of this finding of SDF-1-CXCR4-independent BM homing, the unique role of SDF-1 in HSPC homing has recently been challenged. While SDF-1 is the only chemokine that chemoattracts HSPCs, other chemoattractants for these cells have recently been described, including …

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Learning Takes Flight In Excell In Stem Program, Kassidy Taylor Aug 2015

Learning Takes Flight In Excell In Stem Program, Kassidy Taylor

UNH Today Archive

No abstract provided.

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A Framework For Inferring Unobserved Multistrain Epidemic Subpopulations Using Synchronization Dynamics, Eric Forgoston, Leah B. Shaw, Ira B. Schwartz Aug 2015

A Framework For Inferring Unobserved Multistrain Epidemic Subpopulations Using Synchronization Dynamics, Eric Forgoston, Leah B. Shaw, Ira B. Schwartz

Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works

A new method is proposed to infer unobserved epidemic subpopulations by exploiting the synchronization properties of multistrain epidemic models. A model for dengue fever is driven by simulated data from secondary infective populations. Primary infective populations in the driven system synchronize to the correct values from the driver system. Most hospital cases of dengue are secondary infections, so this method provides a way to deduce unobserved primary infection levels. We derive center manifold equations that relate the driven system to the driver system and thus motivate the use of synchronization to predict unobserved primary infectives. Synchronization stability between primary and …

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Increased Expression Of Fatty Acid Synthase Provides A Survival Advantage To Colorectal Cancer Cells Via Upregulation Of Cellular Respiration, Yekaterina Y. Zaytseva, Jennifer W. Harris, Mihail I. Mitov, Ji Tae Kim, D. Allan Butterfield, Eun Young Lee, Heidi L. Weiss, Tianyan Gao, B. Mark Evers Aug 2015

Increased Expression Of Fatty Acid Synthase Provides A Survival Advantage To Colorectal Cancer Cells Via Upregulation Of Cellular Respiration, Yekaterina Y. Zaytseva, Jennifer W. Harris, Mihail I. Mitov, Ji Tae Kim, D. Allan Butterfield, Eun Young Lee, Heidi L. Weiss, Tianyan Gao, B. Mark Evers

Markey Cancer Center Faculty Publications

Fatty acid synthase (FASN), a lipogenic enzyme, is upregulated in colorectal cancer (CRC). Increased de novo lipid synthesis is thought to be a metabolic adaptation of cancer cells that promotes survival and metastasis; however, the mechanisms for this phenomenon are not fully understood. We show that FASN plays a role in regulation of energy homeostasis by enhancing cellular respiration in CRC. We demonstrate that endogenously synthesized lipids fuel fatty acid oxidation, particularly during metabolic stress, and maintain energy homeostasis. Increased FASN expression is associated with a decrease in activation of energy-sensing pathways and accumulation of lipid droplets in CRC cells …

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Examining The Safety Of Respiratory And Intravenous Inoculation Of Bdellovibrio Bacteriovorus And Micavibrio Aeruginosavorus In A Mouse Model, Kenneth Shatzkes, Richard Chae, Chi Tang, Gregory C. Ramirez, Somdatta Mukherjee, Liana Tsenova, Nancy D. Connell, Daniel E. Kadouri Aug 2015

Examining The Safety Of Respiratory And Intravenous Inoculation Of Bdellovibrio Bacteriovorus And Micavibrio Aeruginosavorus In A Mouse Model, Kenneth Shatzkes, Richard Chae, Chi Tang, Gregory C. Ramirez, Somdatta Mukherjee, Liana Tsenova, Nancy D. Connell, Daniel E. Kadouri

Publications and Research

Bdellovibrio spp. and Micavibrio spp. are Gram-negative predators that feed on other Gram-negative bacteria, making predatory bacteria potential alternatives to antibiotics for treating multi-drug resistant infections. While the ability of predatory bacteria to control bacterial infections in vitro is well documented, the in vivo effect of predators on a living host has yet to be extensively examined. In this study, respiratory and intravenous inoculations were used to determine the effects of predatory bacteria in mice. We found no reduction in mouse viability after intranasal or intravenous inoculation of B. bacteriovorus 109J, HD100 or M. aeruginosavorus. Introducing predators into the respiratory …

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Simulating And Animating The Spatial Dynamics Of Interacting Species Living On A Torus, Boyan Kostadinov Aug 2015

Simulating And Animating The Spatial Dynamics Of Interacting Species Living On A Torus, Boyan Kostadinov

Publications and Research

The goal of this talk is to present a student research project in computational population biology, which aims at creating a computer simulation and animation of the spatial dynamics of interactions between two kinds of species living on a torus-shaped universe. The habitat for spatial interactions is modeled by a 2D lattice with periodic boundary conditions, which wrap the rectangular grid into a torus. The spatial interactions between the species have two components: 1. Population dynamics modeled by the classical Nicholson-Bailey two-parameter family of models for coupled interactions between species, extended to incorporate space and 2. Two-parameter migration dynamics, modeled …

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Identification And Risk Assessment For Worldwide Invasion And Spread Of Tuta Absoluta With A Focus On Sub-Saharan Africa: Implications For Phytosanitary Measures And Management, Henri E.Z. Tonnang, Samira F. Mohamed, Fathiya Khamis, Sunday Ekesi Aug 2015

Identification And Risk Assessment For Worldwide Invasion And Spread Of Tuta Absoluta With A Focus On Sub-Saharan Africa: Implications For Phytosanitary Measures And Management, Henri E.Z. Tonnang, Samira F. Mohamed, Fathiya Khamis, Sunday Ekesi

All Peer-Reviewed Publications

To support management decisions, molecular characterization of data and geo-reference of incidence records of Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) were combined with data on the biology and ecology of the pest to estimate its climatic suitability and potential spread at regional and global scale. A CLIMEX model was developed and used for the global prediction of current and future climate-induced changes in the distributional shifts of T. absoluta. Results revealed that temperature and moisture characterized T. absoluta population growth while the pest ability to survive the cold, hot, wet and dry stress conditions are the primary characteristics defining its range …

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Chemoselective Transfer Hydrogenation Of Nitroarenes Catalyzed By Highly Dispersed, Supported Nickel Nanoparticles, Chengjun Jiang, Zeyu Shang, Xinhua Liang Aug 2015

Chemoselective Transfer Hydrogenation Of Nitroarenes Catalyzed By Highly Dispersed, Supported Nickel Nanoparticles, Chengjun Jiang, Zeyu Shang, Xinhua Liang

Chemical and Biochemical Engineering Faculty Research & Creative Works

A recyclable highly dispersed Ni/SiO2 catalyst was prepared by atomic layer deposition. Chemo selective reduction of nitroarenes was studied using the prepared Ni/SiO2 as the catalyst and hydrazine hydrate as a hydrogen donor. Different kinds of nitroarenes were converted to the corresponding anilines with high yields. The high activity of the catalysts could be a result of the highly dispersed Ni nanoparticles. (Chemical Presented).

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Adopting Agile Practices When Developing Medical Device Software, Martin Mchugh, Fergal Mccaffery, Garret Coady Aug 2015

Adopting Agile Practices When Developing Medical Device Software, Martin Mchugh, Fergal Mccaffery, Garret Coady

Articles

Agile methods are gaining momentum amongst the developers of non-safety critical software. They offer the ability to improve development time, increase quality and reduce development costs. Despite this, the rate of adoption of agile methods within safety critical domains remains low. On face value agile methods appear to be contradictory to regulatory requirements. However while they may appear contradictory, they align on key values such as the development of the highest quality software. To demonstrate that agile methods could in fact be adopted when developing regulatory compliant software they were implemented on a medical device software development project. This implementation …

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Integrating Human Culture, Community, And Sense Of Place Into An Existing High School Environmental Studies Curriculum, Kathy Allen Kline Aug 2015

Integrating Human Culture, Community, And Sense Of Place Into An Existing High School Environmental Studies Curriculum, Kathy Allen Kline

School of Education and Leadership Student Capstone Theses and Dissertations

This capstone addresses challenges faced by a first year high school teacher on an interdisciplinary team integrating social studies into an environmental studies curriculum. After exploring literature in biodiversity, biocultural diversity, and place-based education, the author determines that the existing curriculum can be enhanced to make stronger connections between people and the places already being studied, including the local community. To that end, this paper presents a sub-unit, developed using the Understanding by Design ® model, that seeks to integrate human culture, community, and sense of place into an environmental studies curriculum. The sub-unit includes six weeks of lessons to …

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Electrochemical Characterization Of Protein Adsorption Onto Yngrt-Au And Vlgxe-Au Surfaces, Hanna Trzeciakiewicz, Jose Esteves-Villanueva, Rania Soudy, Kamaljit Kaur, Sanela Martic-Milne Aug 2015

Electrochemical Characterization Of Protein Adsorption Onto Yngrt-Au And Vlgxe-Au Surfaces, Hanna Trzeciakiewicz, Jose Esteves-Villanueva, Rania Soudy, Kamaljit Kaur, Sanela Martic-Milne

Pharmacy Faculty Articles and Research

The adsorption of the proteins CD13, mucin and bovine serum albumin on VLGXE-Au and YNGRT-Au interfaces was monitored by electrochemical impedance spectroscopy in the presence of [Fe(CN)6]3−/4−. The hydrophobicity of the Au surface was tailored using specific peptides, blocking agents and diluents. The combination of blocking agents (ethanolamine or n-butylamine) and diluents (hexanethiol or 2-mercaptoethanol) was used to prepare various peptide-modified Au surfaces. Protein adsorption onto the peptide-Au surfaces modified with the combination of n-butylamine and hexanethiol produced a dramatic decrease in the charge transfer resistance, Rct, for all three proteins. In contrast, polar peptide-surfaces induced a minimal change in …

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Leading And Managing The 21st Century Research University: Creating, Implementing, And Sustaining Strategic Change, Paul W. Ferguson, Gene E. Hall, Julie D. Hopwood Aug 2015

Leading And Managing The 21st Century Research University: Creating, Implementing, And Sustaining Strategic Change, Paul W. Ferguson, Gene E. Hall, Julie D. Hopwood

International Journal of Leadership and Change

Universities are competing in an environment in which only the most adaptable to sustainable change will prosper. In order to evolve in this challenging time, universities must embrace strategies for transformational change. This paper reviews two case studies that illustrate the universal applicability of theories of Change Science for achieving sustainable change in stressful times of prosperity and austerity. Understanding the phases of the Change Process that include Creating Vision, Implementing Vision, and Sustaining Vision can promote sustainable change directly related to the culture and mission of the institution.

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Paleoepidemiology Of Intestinal Parasites And Lice In Pre-Columbian South America *, Adauto Araujo, Karl J. Reinhard, Daniela Leles, Luciana Sianto, Alena Iniguez, Martin Fugassa, Berrnardo Arriaza, Nancy Orellana, Luiz Fernando Ferreira Aug 2015

Paleoepidemiology Of Intestinal Parasites And Lice In Pre-Columbian South America *, Adauto Araujo, Karl J. Reinhard, Daniela Leles, Luciana Sianto, Alena Iniguez, Martin Fugassa, Berrnardo Arriaza, Nancy Orellana, Luiz Fernando Ferreira

Karl Reinhard Publications

Some human parasites originated in prehominid ancestors in Africa. Nematode species, such as Enterobius vermicularis (pinworm), hookworms and Trichuris trichiura are shared by humans and other close phylogenetic primates (Pan and Gorilla), showing that they infected a common ancestor to this group. When humans migrated from Africa to other continents they carried these parasites wherever climate conditions allowed parasite transmission from host to host. Other parasites, however, were acquired throughout human biological and social evolutive history when new territories were occupied. Paleoparasitology data is a valuable source to recover emergence and disappearance of parasite infections through analysis of archaeological remains. …

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Diet And Parasitism At Dust Devil Cave, Karl J. Reinhard, J Richard Ambler, Magdalene Mcguffie Aug 2015

Diet And Parasitism At Dust Devil Cave, Karl J. Reinhard, J Richard Ambler, Magdalene Mcguffie

Karl Reinhard Publications

Human parasitism has obvious relationships to group size and composition, mobility, subsistence patterns, and rates of culture change. At their best, human endoparasites may be annoying; at their worst, some can cause death. Thus, an overall view of the parasite load of a prehistoric population can yield insights useful in interpreting past lifeways. With these thoughts in mind, we undertook a study of Desha Complex (6800-4800 B .C.) human feces recovered from Dust Devil Cave in southern Utah.

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An Audit Of Records And Information Management Practices And Icts Utilisation Among Smes In Northern Uganda, Constant Okello-Obura Dr., Faridah Muzaki Aug 2015

An Audit Of Records And Information Management Practices And Icts Utilisation Among Smes In Northern Uganda, Constant Okello-Obura Dr., Faridah Muzaki

Library Philosophy and Practice (e-journal)

Good management practices for records and information are now becoming key norms in organisations due to the value attached to records and information. This is because records and information is considered the life blood of business transactions. However, with the advancement in technologies, the business enterprises need to rethink the ways they manage records and information (RIM). This study was carried out in northern Uganda among the SMEs to make an audit of RIM with special focus on the life cycle of RIM and application of ICTs in RIM functions. It also investigated the management of e-mail as valuable records …

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Peptide-Capped Nanoparticles For Catalysis And Assembly, Beverly D. Briggs Aug 2015

Peptide-Capped Nanoparticles For Catalysis And Assembly, Beverly D. Briggs

Open Access Dissertations

Nature possesses methods for the formation and manipulation of inorganic materials with controlled size, shape, and compositions. Biomolecules, such as peptides, are known to be responsible for the generation of such inorganic materials on the nanoscale, where the enhanced properties can be exploited for various applications. Pd nanoparticles, capped with the Pd-specific Pd4 peptide (TSNAVHPTLRHL), were found to be active catalysts for Stille coupling, where the debated mechanism of oxidative addition was explored. Furthermore, the same Pd4-capped nanoparticles were found to be active in Suzuki coupling, another C-C coupling reaction that undergoes catalysis following a similar mechanism. Other considerations with …

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The Role Of Arabidopsis Aminoalcoholphosphotransferase 1 And 2 In Plant Development And Oil Production And Transcriptional Regulation Of Seed Oil Accumulation By Glabra2, Yu Liu Aug 2015

The Role Of Arabidopsis Aminoalcoholphosphotransferase 1 And 2 In Plant Development And Oil Production And Transcriptional Regulation Of Seed Oil Accumulation By Glabra2, Yu Liu

Dissertations

Vegetable oils are important commodities as human foods, animal feeds, renewable industrial feedstocks, and biofuels. Many biochemical and regulation events are involved in seed oil formation, including phospholipids metabolism and transcriptional regulation. In this work, I investigated 1) the role of aminoalcoholphosphotransferases (AAPTs) in phospholipid synthesis and plant development, 2) the effects of AAPTs on seed storage lipid production in Arabidopsis and the emerging oil crop Camelina, and 3) the interaction of the lipid mediator phosphatidic acid (PA) with GLABRA2 (GL2), a negative regulator in seed oil production. AAPTs are the enzymes that produce phosphatidylcholine (PC) and phosphatidylethanolamine (PE). The …

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Proteins Of Bartonella Bacilliformis:Candidates For Vaccine Development, Cesar Henriquez-Camocho, Palmira Ventosilla, Michael F. Minnick, Joaquim Ruiz, Ciro Maguina Aug 2015

Proteins Of Bartonella Bacilliformis:Candidates For Vaccine Development, Cesar Henriquez-Camocho, Palmira Ventosilla, Michael F. Minnick, Joaquim Ruiz, Ciro Maguina

Biological Sciences Faculty Publications

Bartonella bacilliformis is the etiologic agent of Carrion's disease suggest complex adaptations by the bacterium to the human host, with the overall objectives of persistence, maintenance of a reservoir state for vectorial transmission, and immune evasion. These events include a multitude of biochemical and genetic mechanisms involving both bacterial and host proteins. This review focuses on proteins involved in interactions between B. bacilliformis and human host. Some of them (e.g., flagellin, Brps, IalB, FtsZ, Hbp/Pap31, and other outer membrane proteins) are potential protein antigen candidates for a synthetic vaccine.

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A Look Inside The Eye With Professor Rick Cote, Paige Belisle Aug 2015

A Look Inside The Eye With Professor Rick Cote, Paige Belisle

UNH Today Archive

No abstract provided.

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Calmodulin Methyltransferase Is Required For Growth, Muscle Strength, Somatosensory Development And Brain Function, Sitvanit Haziza, Roberta Magnani, Dima Lan, Omer Keinan, Ann Saada, Eli Hershkovitz, Nurit Yanay, Yoram Cohen, Yoram Nevo, Robert L. Houtz, Val C. Sheffield, Hava Golan, Ruti Parvari Aug 2015

Calmodulin Methyltransferase Is Required For Growth, Muscle Strength, Somatosensory Development And Brain Function, Sitvanit Haziza, Roberta Magnani, Dima Lan, Omer Keinan, Ann Saada, Eli Hershkovitz, Nurit Yanay, Yoram Cohen, Yoram Nevo, Robert L. Houtz, Val C. Sheffield, Hava Golan, Ruti Parvari

Horticulture Faculty Publications

Calmodulin lysine methyl transferase (CaM KMT) is ubiquitously expressed and highly conserved from plants to vertebrates. CaM is frequently trimethylated at Lys-115, however, the role of CaM methylation in vertebrates has not been studied. CaM KMT was found to be homozygously deleted in the 2P21 deletion syndrome that includes 4 genes. These patients present with cystinuria, severe intellectual disabilities, hypotonia, mitochondrial disease and facial dysmorphism. Two siblings with deletion of three of the genes included in the 2P21 deletion syndrome presented with cystinuria, hypotonia, a mild/moderate mental retardation and a respiratory chain complex IV deficiency. To be able to attribute …

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The Correlation Between Athletic Intrinsic Motivation And Academic Intrinsic Motivation Of Student Athletes At The Secondary Level, Rebecca Lee Jelenc Aug 2015

The Correlation Between Athletic Intrinsic Motivation And Academic Intrinsic Motivation Of Student Athletes At The Secondary Level, Rebecca Lee Jelenc

School of Education and Leadership Student Capstone Theses and Dissertations

The research question addressed in this project is: Is there a correlation between athletic and academic intrinsic motivation secondary students ? The motivating factor for this capstone was the study of high academic success by highly successful student athletes in high school. This capstone was designed to investigate if intrinsic motivation attributes of athletics are transferred to the academic focus of the athletes. This capstone details related literature on intrinsic motivation in both the athletic and academic setting, the use of the Academic and Sports Motivation Surveys, and results of the surveys. The study of Marionville High School student athlete’s …

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