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The Role Of Ovarian Function In The Progression Of Cachexia In The ApcMin/+ Mouse, Kimbell Louise Hetzler

Theses and Dissertations

Cachexia is a devastating a life-threatening condition that occurs secondary to underlying disease including cancer, AIDS, COPD and comprises severe loss of muscle and fat mass. Muscle mass atrophy and wasting with cachexia is especially dire, as skeletal muscle mass is associated with quality of life, functionality, and ability to respond to chemotherapeutics. While much investigation has been done in the male animal to elucidate the inflammatory pathways and muscle signaling underlying cachexia, very little work has occurred in the female. The overall purpose of this study is to determine if ovarian function can alter cachexia progression in the female …

Supramolecular Coordination Networks Of S- And F-Block Metals Featuring The 1,8-Naphthalimide Tecton, Andrew Paul Leitner

Theses and Dissertations

The reactions of (S)-2-(1,8-naphthalimido)propanoic acid (HLala), and (S)-2-(1,8- naphthalimido)-3-hydroxypropanoic acid (HLser), protonated forms of ligands that contain a carboxylate donor group, an enantiopure chiral center and a 1,8-naphthalimide π...π stacking supramolecular tecton and in the case of HLser an alcohol functional group, with the appropriate alkali metal hydroxide followed by a variety of crystallization methods leads to the formation of crystalline K(Lala)(MeOH) (1), K(Lala)(H2O) (2), Na(Lala)(H2O) (3), KLser (4), CsLser (5) and CsLala (6). Each of these new complexes has a solid state structure based on six-coordinate metals linked into homochiral helical rod SBU central cores. In addition to the …

Invective Drag: Talking Dirty In Catullus, Cicero, Horace, And Ovid, Casey Catherine Moore

Theses and Dissertations

Invective Drag: Talking Dirty in Catullus, Cicero, Horace, and Ovid, studies the relationship between invective texts and masculine self-fashioning. Using gender theory, rhetorical theory, and philology, I examine how invective speech in these authors operates outside the normative social parameters of Roman masculinity.. I examine the invectives of Catullus, Cicero, Horace, and Ovid to argue that in the speaker’s aggressive articulation of masculinity, he often ends up effeminizing or queering himself as he attempts to make his opponents radically other. I show that the hypermasculine speaker of the invective genre utilizes a strategy I term “invective drag,” the adoption of …

Framing Death: Politics, Meaning, And The Strategic Communication Of Organ Donation Messages In South Carolina, Jeremy T. Vanderknyff

Theses and Dissertations

This study applies framing theory within a critical-interpretive anthropological context to understand how organ procurement organizations (OPOs) design messages to promote organ donation registration and how cultural factors including notions of embodiment and structural inequalities influence audiences’ processing of those messages. The first part of the study employs content analysis to deductively identify OPO-produced message frames. The second part of the study uses focus groups across South Carolina to explore audience reactions to different message frames. Themes from donors and non-donors alike reflected a mistrust of the medical establishment, a keen awareness of structural inequality, and complex notions of embodiment …

Global Methylation Of Dna Among Spartina Alterniflora Clones Differing In Age At North Inlet, Sc, Trenton Agrelius

Theses and Dissertations

“Brown marsh” or “sudden marsh dieback” refers to the rapid death of patches varying in size of Spartina alterniflora. In 2000 following a 100-year record drought, approximately 8,000 hectares of S. alterniflora died along the Louisiana coast, which prompted Louisiana Governor Foster to declare a state of emergency. Other cases have been documented at North Inlet, SC as well as various other marshes along the southeastern United States. Currently, there is much dispute regarding the cause of “sudden marsh dieback” but environmental stress is one of the acknowledged constants across sites. We hypothesized an alternative mechanism in which methylation of …

Nd − Pdpa: N Dimensional Probability Density Profile Analysis, Arjang Fahim

Theses and Dissertations

Proteins are often referred as working molecule of a cell, performing many structural, functional and regulatory processes. Revealing the function of proteins still remains a challenging problem. Advancement in genomics sequence projects produces large protein sequence repository, but due to technical difficulty and cost related to structure determination, the number of identified protein structure is far behind. Novel structures identification are particularly important for a number of reasons: they generate models of similar proteins for comparison; identify evolutionary relationships; further contribute to our understanding of protein function and mechanism; and allow for the fold of other family members to be …

Week Of December 14, 2015, New York Medical College

InTouch

• Summer Fellowship Pays Off in the Form of Published Research
• Department of Surgery Hosts Twelfth Annual Louis R.M. Del Guercio, M.D., Distinguished Visiting Professorship and Research Day
• D.P.T. Students Share Their Community Service Projects
• Department of Pediatrics Hosts Fifth Annual Assistant Professor Pediatric Research Symposium
• NYMC Serves Up International Food and Handicrafts
• P2P Committee Recognizes Role Models at NYMC

Searching For Connection: A Heuristic Study Of The Role Of Consciousness In Identifying And Meeting Human Needs Through Expressive Movement, Amy Leow

Creative Arts Therapies Theses

The purpose of this study was to draw initial conclusions regarding the relationships between expressive movement, consciousness, and human needs. Additionally, this study also aimed to illustrate how the process of shifting conscious awareness through expressive movement enables clients of DMT to identify and meet their needs. Data was collected using a heuristic examination of my own experience, as the only participant of this study, engaging in six Authentic Movement sessions over six weeks. Data analysis, using a heuristic methodology, resulted in several conclusions which piece together an initial framework from which to understand how the process of shifting conscious …

Commencement Convocation Program, St. Petersburg Campus, December 13, 2015, University Of South Florida St. Petersburg

USF St. Petersburg Graduations and Commencements

King O'Neal Award: Nora Khatcherian, Taylor Lents, Siarra Rogers; Outstanding Graduate: Rachel Gordon; Regional Chancellor's Award for Civic Leadership: Paul C. Tash

Plague And Perception: The English Interpretation Of Plague In Massachusetts, Sarah Peck

Honors Program Theses and Projects

Evidence suggests that the early economic and political success of the English in Plimoth Colony is due to the introduction of European diseases into coastal Massachusetts during the late sixteenth century. Building upon Alfred Crosby’s 1972 publication The Columbian Exchange, modern environmental historians and cultural historians recognize the important interconnection between parasitism, disease, and historic trends. It is now fairly well recognized in both the science and humanities disciplines that any study of the political and economic development of European settlements and colonization of the Americas correlates with studies and research about the introduction of foreign diseases, as well as …

Mobile Mud Dynamics In The East China Sea Elucidated Using 210pb, 137cs, 7be, And 234th As Tracers, Jinlong Wang, Jinzhou Du, Mark Baskaran, Jing Zhang

Environmental Science and Geology Faculty Research Publications

“Mobile mud” (MM), which has fine grain size distribution (>90% clay + silt, and <5% sand) and high porosity (≥0.50), plays an important role in the biogeochemical cycles in the estuarine areas and the inshore shelf. A suite of MM samples from the coastal area of the East China Sea (ECS) was collected in spring and summer of 2011 to observe their spatial and temporal distribution, grain size, and radionuclides concentrations. The MM thickness ranged from 0.5 to 11 cm (average: 2.2 cm (May) and 3.9 cm (August)). The thick mud layer is mainly distributed along the coast, with an area of 2.2 × 104 km2 in May and 1.5 × 104 km2 in August, with corresponding masses of 8.8 × 108 and 7.8 × 108 t, respectively. The estimated masses of MM are considerably larger than the annual sediment discharge mass of the Changjiang River. The distribution of 137Cs inventories in MM indicates that 137Cs can be effectively utilized as a transport tracer of MM in the river‐dominated estuaries and coastal areas. The higher inventories of 7Be in MM in the river mouth in spring are attributed to higher depositional flux and higher sediment discharge. The ratio of the MM inventory of 234Thex/production in the overlying water column of >2.5 in south inshore indicates that the sediment focusing resulted in the increased mass flux. The residence time of MM is estimated as 3–6 years both by mass balance of MM and 210Pbex in MM.

Fall 2015 Commencement Program, University Of Alabama In Huntsville

Commencement Programs

No abstract provided.

2015 Fall - Commencement Program, Office Of The Registrar, East Tennessee State University

ETSU Commencement Ceremonies and Programs

No abstract provided.

Ua45/6 Commencement Program, Wku Registrar

WKU Administration Documents

Commencement program listing graduates.

Commencement Convocation Program, Usf, Graduate, December 12, 2015, University Of South Florida

USF Graduation and Convocation Programs

Honorary Doctor of Business - Tod Leiwecke

Cyclin D1 Silencing Suppresses Tumorigenicity, Impairs Dna Double Strand Break Repair And Thus Radiosensitizes Androgenindependent Prostate Cancer Cells To Dna Damage., F Marampon, G L Gravina, Xiaoming Ju, A Vetuschi, R Sferra, Mathew C Casimiro, S Pompili, C Festuccia, A Colapietro, E Gaudio, E Di Cesare, V Tombolini, Richard Pestell

Department of Cancer Biology Faculty Papers

Patients with hormone-resistant prostate cancer (PCa) have higher biochemical failure rates following radiation therapy (RT). Cyclin D1 deregulated expression in PCa is associated with a more aggressive disease: however its role in radioresistance has not been determined. Cyclin D1 levels in the androgen-independent PC3 and 22Rv1 PCa cells were stably inhibited by infecting with cyclin D1-shRNA. Tumorigenicity and radiosensitivity were investigated using in vitro and in vivo experimental assays. Cyclin D1 silencing interfered with PCa oncogenic phenotype by inducing growth arrest in the G1 phase of cell cycle and reducing soft agar colony formation, migration, invasion in vitro and tumor …

Illinois State University, One Hundred And Fifty-Sixth Annual Commencement, December 12, 2015, Illinois State University

Commencement Programs

Illinois State University
One Hundred and Fifty-Sixth Annual Commencement
December 12, 2015

The Invasive Coral Oculina Patagonica Has Not Been Recently Introduced To The Mediterranean From The Western Atlantic Speciation And Evolutionary Genetics, Karine Posbic Leydet, Michael E. Hellberg

Faculty Publications

© 2015 Leydet and Hellberg; licensee BioMed Central. Background: Effective policies, management, and scientific research programs depend on the correct identification of invasive species as being either native or introduced. However, many species continue to be misidentified. Oculina patagonica, first recorded in the Mediterranean Sea in 1966, is believed to have been introduced in anthropogenic times and expanding in a west to east direction. However, its present identification and status as a recently introduced species remain to be explored. In this study, we used multi-locus genetic data to test whether O. patagonica in the Mediterranean has been recently introduced from …

Commencement Convocation Exercises - December 2015, Prairie View A&M University

Commencement and Convocation Exercises

No abstract provided.

Listening Strategies For English Language Learner Comprehension, A Teacher Resource Guide, Ana Marie Ruiz Mclafferty

School of Education and Leadership Student Capstone Theses and Dissertations

This capstone examines listening strategies for English Language Learners in grades 3-5 and includes a teacher resource guide to help support students in the listening language domain. There are very few resources for elementary teachers to support students in listening comprehension strategies. The teacher resource guide includes think-aloud, focus questions, journaling and interactive listening strategies. Lesson templates and examples are included.

Isolasi Dan Molecular Docking Senyawa 6,7-Dihidro-17-Hidroksierisotrin Dari Daun Dadap Belendung (Erythrina Poeppigiana) Terhadap Aktivitas Sitotoksik Antikanker Payudara Mcf-7, Richa Mardianingrum, Tati Herlina, Unang Supratman

Chimica et Natura Acta

Erythrina (Leguminose) memiliki jumlah alkaloid paling banyak jika dibandingkan dengan senyawa metabolit sekunder lainnya, sehingga tumbuhan Erythrina dikenal dengan sebutan alkaloid eritrina. Erythrina yang paling banyak tumbuh di Indonesia adalah E. poeppigiana. Tujuan penelitian ini adalah untuk mengungkapkan senyawa aktif antikanker payudara MCF-7 secara in silico yang terdapat di dalam daun E. poeppigiana. Alkaloid dipisahkan dan dimurnikan melalui tahapan ekstraksi, fraksinasi, pemisahanan dan pemurnian yang dipandu dengan uji Dragendorff, senyawa alkaloid yang diperoleh diuji antikanker secara in silico terhadap reseptor EGFR2 yang bekerja pada sel kanker payudara MCF-7 menggunakan program ArgusLab dengan pembanding canertinib dan parameter yang diukur adalah energi …

Pengaruh Konsumsi Yogurt Yang Dibuat Dengan Kultur Dua Bakteri (Sterptococcus Thermophillus Dan Lactobacillus Bulgaricus) Dan Tiga Bakteri (Sterptococcus Thermophillus, Lactobacillus Bulgaricus Dan Lactobacillus Acidophilus) Terhadap Kadar Kolesterol Serum Darah Tikus, Safri Ishmayana, Asep Juanda, O. Suprijana, Sadiah Djajasoepena, Idar Idar, Saadah D. Rachman

Chimica et Natura Acta

Tingginya kadar kolestrol serum darah berhubungan dengan meningkatnya resiko aterosklerosis dan penyakit jantung koroner. Produk susu terfermentasi seperti yogurt dapat menurunkan kadar kolesterol serum darah sehingga dapat meningkatkan resiko kedua penyakit tersebut. Penelitian ini bertujuan untuk mempelajari pengaruh konsumsi yogurt yang dibuat dengan dua dan tiga bakteri terhadap kadar kolesterol serum darah tikus putih. Pada percobaan ini 15 tikus putih jenis Wistar dibagi menjadi empat kelompok, masing-masing kelompok tiga atau empat ekor. Kelompok pertama diberi pakan dan air, kelompok kedua diberi pakan dan susu murni, kelompok ketiga diberi pakan dan yogurt 2 bakteri sedangkan kelompok keempat diberi pakan dan yogurt …

Pemanfaatan Kulit Kacang Tanah (Arachis Hypogaea) Untuk Bioadsorpsi Logam Kalsium Dan Magnesium, Uji Pratomo, Rubianto A. Lubis, Diana Hendrati, Titin Sofyatin, Vidia Afina Nuraini

Chimica et Natura Acta

Masyarakat Indonesia banyak menggunakan air tanah sebagai sumber air untuk keperluan rumah tangga dan industri. Kontaminan air tanah penyebab kesadahan berupa ion-ion divalen Ca2+ dan Mg2+ menimbulkan masalah bagi penggunaan domestik dan industri, seperti terbentuknya kerak pada peralatan dan konsumsi deterjen yang lebih tinggi. Salah satu metode yang efektif untuk melunakkan air sadah adalah adsorpsi menggunakan biosorben. Biosorben yang digunakan pada penelitian ini adalah kulit kacang tanah (Arachis hypogaea L.) yang mengandung berbagai gugus fungsi sehingga efektif mengadsorpsi ion-ion logam Ca2+ dan Mg2+ dalam matriks air sadah. Adsorpsi dengan metode batch dilakukan melalui berbagai variasi berat adsorben, pH, dan waktu …

Sintesis Prekursor Senyawa Beauvericin, Asam (2r)-Asetiloksiisovalerat, Rani Maharani, Taufiqqurahman Taufiqqurahman, Dina Puspitasari

Chimica et Natura Acta

Beauvericin merupakan heksadepsipeptida siklik yang diproduksi oleh berbagai jamur seperti Beauveria bassiana dan Fussarium spp. Penelitian mengenai sintesis senyawa beauvericin telah dilakukan melalui media mikrobiologi, namun sintesis dengan metode sintesis peptida masih belum banyak dilaporkan. Sedikitnya laporan mengenai sintesis senyawa beauvericin disebabkan sulitnya akses terhadap pengadaan material sintesis atau prekursor senyawa yang bersangkutan.Prekursor dari senyawa beauvericin adalah asam amino N-metilfenilalanin dan asam hidroksi isovalerat. Dalam kaitannya dengan sintesis total peptida dalam fase padat yang akan dilakukan, asam hidroksi isovalerat (Hiv) akan sulit ditambahkan ke dalam resin, sehingga senyawa ini harus ditambahkan kedalam resin dalam bentuk depsidipeptida, Fmoc-MePhe-Hiv.Sintesis depsidipeptida ini merupakan …

Potensi Enzim Α-Amilase Dari Bacillus Sp. (Termamyl®) Untuk Pemrosesan Tepung Sorgum, Muhammad Fadhlillah, Soetijoso Soemitro, Toto Subroto

Chimica et Natura Acta

Tepung sorghum merupakan salah satu sumber karbohidrat non gluten yang dapat digunakan sebagai pengganti gandum. Sayangnya, makanan berbahan dasar sorgum seperti roti sorgum memiliki kecenderungan penurunan kualitas tekstur lebih cepat selama penyimpanan. α-Amilase rutin digunakan dalam pembuatan roti gandum sebagai antifirming untuk menghasilkan kualitas yang lebih baik. Pada penelitian ini dilakukan penentuan karakter enzim α-amilase komersial (Termamyl®) serta menentukan potensinya untuk digunakan dalam pemrosesan tepung sorgum. Hasil penelitian menunjukkan bahwa Termamyl® memiliki kemampuan untuk memecah pati mentah. Penelitian lebih lanjut menunjukkan bahwa tepung sorgum yang diberi perlakuan Termamyl® mengubah bentuk granula pati sorgum dan juga mengurangi kandungan amilosa sebesar 27%.

Penapisan Fitokimia Dan Uji Toksisitas Dari Daun Myristica Fatua Houtt, Sofa Fajriah, Megawati Megawati

Chimica et Natura Acta

Myristica fatua merupakan salah satu tumbuhan obat asli Indonesia yang berpotensi untuk dikembangkan. Telah dilakukan penapisan fitokimia dan uji toksisitas menggunakan metode BSLT (Brine Shrimp Lethality Toxicity) terhadap ekstrak metanol, ekstrak aseton dan etanol 70%. Selanjutnya ekstrak metanol difraksinasi untuk memperoleh fraksi n-heksana, etil asetat, dan n-butanol dari daun Myristica fatua Houtt dan dilakukan uji toksisitas lebih lanjut. Hasil penapisan fitokimia menunjukkan bahwa daun M. fatua mengandung senyawa terpenoid, steroid, flavonoid, saponin, dan tanin. Potensi antikanker juga ditunjukkan terhadap ekstrak metanol dan fraksi etil asetat yang mempunyai toksisitas paling tinggi dari fraksi lainnya dengan LC50 masing-masing adalah sebesar 64,57 dan …

The Emotional Effect Of Same Sex Grouping, Katherine Barwacz Heidrick

School of Education and Leadership Student Capstone Theses and Dissertations

The research question addressed in this project was, how do gender roles affect the achievement of school-aged children? It documents one teachers research in her fifth grade classroom by creating a curriculum related challenge that students worked on in mixed gender groups and same gender groups. The author documents the details of the research literature review in order to analyze and validate the study. The action research portion included surveys that students responded to, asking them to reflect over their experience. In conclusion, the author describes both successes and struggles of working with mixed and same gender groups and concludes …

The Effect Of Oil Sands Process-Affected Water And Model Naphthenic Acids On Photosynthesis And Growth In Emiliania Huxleyi And Chlorella Vulgaris., Jessica Beddow, Richard J. Johnson, Tracy Lawson, Mark N. Breckels, Richard J. Webster, Ben E. Smith, Steven J. Rowland, Corinne Whitby

More Faculty of Science and Engineering Research

Naphthenic acids (NAs) are among the most toxic organic pollutants present in oil sands process waters (OSPW) and enter marine and freshwater environments through natural and anthropogenic sources. We investigated the effects of the acid extractable organic (AEO) fraction of OSPW and individual surrogate NAs, on maximum photosynthetic efficiency of photosystem II (PSII) (FV/FM) and cell growth in Emiliania huxleyi and Chlorella vulgaris as representative marine and freshwater phytoplankton. Whilst FV/FM in E. huxleyi and C. vulgaris was not inhibited by AEO, exposure to two surrogate NAs: (4'-n-butylphenyl)-4-butanoic acid (n-BPBA) and (4'-tert-butylphenyl)-4-butanoic acid (tert-BPBA), caused complete inhibition of FV/FM in …

The Effect Of Sleep Deprivation On Cadet Performance And Behavior: A Proposal To Reform The Rotc Program At James Madison University, Josh Wells

James Madison Undergraduate Research Journal (JMURJ)

This paper addresses the problem of sleep deprivation among cadets in the Army ROTC program at James Madison University. Drawing on existing research and Army doctrine, the author examines the necessity of sleep for decision making, the biological consequences of sleep deprivation, and the effects of sleep deprivation on emotional intelligence. The paper also questions large, early-morning Physical Training (PT) sessions and their effectiveness in developing group cohesion. After comparing the research to the practices of the ROTC program, the author proposes a new training method for ROTC cadets to address the problems of sleep deprivation and large group PT.

Thinking And Making: Art And Craft In Library Of Congress Classification, Rochelle Smith

Library Philosophy and Practice (e-journal)

Why are art and craft so widely separated in the Library of Congress Classification (LC) System? All classification systems give insight into worldviews prevalent at the time they were created, and library systems are especially illustrative of the cultures and cultural moments which shaped them. The separation of art and craft in LC, in N and TT respectively, compared to their collocation in LC’s contemporaries, Dewey Decimal Classification and Cutter’s Expansive Classification, suggests divergent views of the arts within librarianship, illuminating American views on the relative definitions of art and craft from the mid-nineteenth through the early twentieth centuries.