Digital Commons Network^™

The Scarlet - Volume Xcv, No. 8 (November 13, 2015), Scarlet Staff

The Scarlet (Student Newspaper) (2011-present)

The November 13, 2015 edition of The Scarlet (est. 1939), Clark University's student-run newspaper. The Scarlet is intellectually and editorially independent of the University.

Volume Cxxxiii, Number 9, November 13, 2015, Lawrence University

The Lawrentian

No abstract provided.

Victoria And Rick Mendoza, Csusb

South Colton Oral History Project Collection

No abstract provided.

Science Undergraduate Research Conference 2015 Booklet, Dublin Institute Of Technology, Institute Of Technology, Tallaght, Institute Of Technology, Blanchardstown

Group Reports

Dublin Institute of Technology (DIT), IT Tallaght and IT Blanchardstown hosted the Science Undergraduate Research Conference (SURC 2015) on 13th November 2015 in DIT's Grangegorman Campus. 25 students from DIT, IT Tallaght and IT Blanchardstown who completed an undergraduate research project in a Scientific discipline in the academic year 2014-15 presented at this conference.

The aims of the conference were to:

1. Provide current students with an opportunity to gain an understanding of the work which has been undertaken by recent graduates, and the career opportunities that exist for graduates in Scientific disciplines.
2. Provide recent graduates with an opportunity to gain …

Conserved Molecular Underpinnings And Characterization Of A Role For Caveolin-1 In The Tumor Microenvironment Of Mature T-Cell Lymphomas, Tyler A. Herek, Timothy D. Shew, Heather N. Spurgin, Christine E. Cutucache

Biology Faculty Publications

Neoplasms of extra-thymic T-cell origin represent a rare and difficult population characterized by poor clinical outcome, aggressive presentation, and poorly defined molecular characteristics. Much work has been done to gain greater insights into distinguishing features among malignant subtypes, but there also exists a need to identify unifying characteristics to assist in rapid diagnosis and subsequent potential treatment. Herein, we investigated gene expression data of five different mature T-cell lymphoma subtypes (n = 187) and found 21 genes to be up- and down-regulated across all malignancies in comparison to healthy CD4+ and CD8+ T-cell controls (n = 52). From these results, …

Species Specific Microcalcification In Reef Building Caribbean Corals In Ocean Acidification Conditions, Ashley M. Dungan

HCNSO Student Theses and Dissertations

Coral reefs are one of the most economically important ecosystems on the planet. Despite their great contribution to the world economy, anthropogenic influence via carbon dioxide emissions is leading to unprecedented changes with concerns about subsequent negative impacts on reefs. Surface ocean pH has dropped 0.1 units in the past century; in spite of this rapid shift in oceanic chemistry, it is unclear if individual species or life stages of Caribbean stony corals will be more sensitive to ocean acidification (OA). Examined is the relationship between CO₂-induced seawater acidification, net calcification, photosynthesis, and respiration in three model Caribbean …

Biotechnology Trailblazer: Hayat Sindi (Vol. 3 Issue 1), Global Leadership Dialogues

Global Leadership Dialogues

Hayat Sindi is cofounder of Diagnostics For All, a Massachusetts nonprofit that designs low-cost diagnostic devices to improve health services in developing countries. She is also president of the i2: Institute for Imagination and Ingenuity, an organization that seeks to engage scientists, technologists, and engineers in entrepreneurship and social innovation. She earned a degree in pharmacology from King’s College in London and became the first woman from the Arabian Gulf to earn a PhD in biotechnology, which she completed at Cambridge University. She has combined her knowledge of biotechnology and pharmacology to aid in the invention of low-cost, portable, and …

Curriculum Minutes 11/13/2015, Curriculum Committee

Curriculum Committee Minutes

In these minutes: Approval of Courses; and Continued General Education Discussion

A Forward Genetic Screen Reveals Novel Independent Regulators Of Ulbp1, An Activating Ligand For Natural Killer Cells, Benjamin G Gowen, Bryan Chim, Caleb D. Marceau, Trever T Greene, Patrick Burr, Jeanmarie R. Gonzalez, Charles Hesser, Peter A. Dietzen, Teal Russell, Alexandre Iannello, Laurent Coscoy, Charles L. Sentman

Dartmouth Scholarship

Recognition and elimination of tumor cells by the immune system is crucial for limiting tumor growth. Natural killer (NK) cells become activated when the receptor NKG2D is engaged by ligands that are frequently upregulated in primary tumors and on cancer cell lines. However, the molecular mechanisms driving NKG2D ligand expression on tumor cells are not well defined. Using a forward genetic screen in a tumor-derived human cell line, we identified several novel factors supporting expression of the NKG2D ligand ULBP1. Our results show stepwise contributions of independent pathways working at multiple stages of ULBP1 biogenesis. Deeper investigation of selected hits …

Circulation Analysis Two Ways: In-House & Oclc Collection Evaluation, H. Caroline Hassler

Faculty and Staff

The University of Alaska Southeast Egan Library has been analyzing circulation data for several years using reports from the Sirsi-Dynix ILS and freely available online tag cloud generating tools. Librarians use these tools to produce lists of most highly circulating items and subjects. These lists are used to guide collection development. In 2015, the library purchased a subscription to OCLC’s Collection Evaluation tool. The library does not use any other OCLC Worldshare Management Services. The library uploaded circulation data into OCLC Collection Evaluation and created reports available in that system. This poster session will compare the type of reports generated …

Intrinsic Challenges In Ancient Microbiome Reconstruction Using 16s Rrna Gene Amplification, Kirsten Ziesemer, Allison Mann, Krithivasan Sankaranarayanan, Hannes Schroeder, Andrew T. Ozga, Bernd W. Brandt, Egija Zaura, Andrea Waters-Rist, Menno Hoogland, Domingo C. Salazar-Garcia, Mark Aldenderfer, Camilla Speller, Jessica Hendy, Darlene A. Weston, Sandy J. Macdonald, Gavin H. Thomas, Matthew J. Collins, Cecil M. Lewis Jr., Corinne Hofman, Christina Warinner

Biology Faculty Articles

To date, characterization of ancient oral (dental calculus) and gut (coprolite) microbiota has been primarily accomplished through a metataxonomic approach involving targeted amplification of one or more variable regions in the 16S rRNA gene. Specifically, the V3 region (E. coli341–534) of this gene has been suggested as an excellent candidate for ancient DNA amplification and microbial community reconstruction. However, in practice this metataxonomic approach often produces highly skewed taxonomic frequency data. In this study, we use non-targeted (shotgun metagenomics) sequencing methods to better understand skewed microbial profiles observed in four ancient dental calculus specimens previously analyzed by amplicon …

The Genome Russia Project: Closing The Largest Remaining Omission On The World Genome Map, T. K. Oleksyk, Vladimir Brukhin, Stephen J. O'Brien

Biology Faculty Articles

We are witnessing the great era of genome exploration of the world, as genetic variation in people is being detailed across multiple varied world populations in an effort unprecedented since the first human genome sequence appeared in 2001. However, these efforts have yet to produce a comprehensive mapping of humankind, because important regions of modern human civilization remain unexplored. The Genome Russia Project promises to fill one of the largest gaps, the expansive regions across the Russian Federation, informing not just medical genomics of the territories, but also the migration settlements of historic and pre-historic Eurasian peoples.

Mice Deficient In Endothelial Α5 Integrin Are Profoundly Resistant To Experimental Ischemic Stroke, Jill Roberts, Leon De Hoog, Gregory J. Bix

Sanders-Brown Center on Aging Faculty Publications

Stroke is a disease in dire need of better therapies. We have previously shown that a fragment of the extracellular matrix proteoglycan, perlecan, has beneficial effects following cerebral ischemia via the α5β1 integrin receptor. We now report that endothelial cell selective α5 integrin deficient mice (α5 KO) are profoundly resistant to ischemic infarct after transient middle cerebral artery occlusion. Specifically, α5 KOs had little to no infarct 2–3 days post-stroke, whereas controls had an increase in mean infarct volume over the same time period as expected. Functional outcome is also improved in the α5 KOs compared with controls. Importantly, no …

Evidence Of Field-Evolved Resistance To Bifenthrin In Western Corn Rootworm (Diabrotica Virgifera Virgifera Leconte) Populations In Western Nebraska And Kansas, Adriano E. Pereira, Haichuan Wang, Sarah N. Zukoff, Lance Meinke, B. Wade French, Blair Siegfried

Department of Entomology: Faculty Publications

Pyrethroid insecticides have been used to control larvae or adults of the western corn rootworm (WCR), Diabrotica virgifera virgifera LeConte, a key pest of field corn in the United States. In response to reports of reduced efficacy of pyrethroids in WCR management programs in southwestern areas of Nebraska and Kansas the present research was designed to establish a baseline of susceptibility to the pyrethroid insecticide, bifenthrin, using susceptible laboratory populations and to compare this baseline with susceptibility of field populations. Concentration-response bioassays were performed to estimate the baseline susceptibility. From the baseline data, a diagnostic concentration (LC99) was determined and …

2015 Northeastern Illinois University Sixth Annual Faculty Research Symposium - Program, Symposium Steering Committee

Faculty Research and Creative Activities Symposium 2010-2017

No abstract provided.

The Wooster Voice (Wooster, Oh), 2015-11-13, Wooster Voice Editors

The Voice: 2012-Present

The Story of the Week in this issue of the Voice is "Dr. Sarah Bolton to be Wooster's next president," reporting on her move from positions at Williams College. Other news articles include "Controversial posters removed" due to Title IX violations and triggering content, "Brush Hall focus groups curently in progress" to outline the uses of the new space, and "Students participate in a fast to show solidarity with Mizzou," due to racial harrasment of the University of Missouri's president. In Features, the Voice looks at Senior I.S.'s devoted to female reproduction, a living wage on campus, and a playground …

Dignitary And Speaker Biographies, Virginia Coastal Policy Center, William & Mary Law School

2015, Show Me the Money: The Economic Realities of Responding to Coastal Change and Adaptation in Virginia

No abstract provided.

Knowledge, Attitudes And Practices (Kap) On Rift Valley Fever Among Pastoralist Communities Of Ijara District, North Eastern Kenya, Ismail H. Abdi, Hippolyte D. Affognon, Anthony K. Wanjoya, Washington Onyango-Ouma, Rosemary Sang

All Peer-Reviewed Publications

Outbreaks of Rift Valley fever (RVF), a mosquito-borne viral zoonosis, have previously been associated with unusually heavy rainfall and extensive flooding. The disease is a serious public health problem in Africa and the Middle East, and is a potential global health threat. In Kenya, outbreaks of the disease have disproportionately affected impoverished pastoralist communities. This study sought to assess the knowledge, attitudes and practices (KAP) regarding RVF among the pastoralists of North Eastern Kenya, and to establish the determinants of KAP on RVF. A cross-sectional study involving 392 pastoralists living in Ijara district (Masalani and Ijara wards) was carried out …

Recombinant Dna Modification Of Gibberellin Metabolism Alters Growth Rate And Biomass Allocation In Populus, Haiwei Lu, Venkatesh Viswanath, Cathleen Ma, Elizabeth Etherington, Palitha Dharmawardhana, Olga Shevchenko, Steven H. Strauss, David W. Pearce, Stewart B. Rood, Victor Busov

Michigan Tech Publications, Part 1

Overexpression of genes that modify gibberellin (GA) metabolism and signaling have been previously shown to produce trees with improved biomass production but highly disturbed development. To examine if more subtle types of genetic modification of GA could improve growth rate and modify tree architecture, we transformed a model poplar genotype (Populus tremula × P. alba) with eight genes, including two cisgenes (intact copies of native genes), four intragenes (modified copies of native genes), and two transgenes (from sexually incompatible species), and studied their effects under greenhouse and field conditions. In the greenhouse, four out of the eight tested genes produced …

The Comparative Impact Of Different Patient-Centered Medical Home Domains On Satisfaction Among Individuals Living With Type Ii Diabetes, Jon Mills, Allyson Hall, Rebecca Tanner, Jeffrey Harman, David L. Wood, Charles Lorbeer

Patient Experience Journal

Chronic illnesses like type 2 diabetes are costly and difficult to treat. Patient-centered medical homes (PCMH) have the potential to improve patient satisfaction in this population. However, which domains have the most impact on patient satisfaction has not been established. The aim of this study was to assess the relative strength of association between seven PCMH domains and two measures of satisfaction. Cross-sectional data were used in this observational study collected from a random sample of adults aged 18-89 with type 2 diabetes (n=1301) seen at 4 PCMHs. The Ambulatory Care Experiences Survey instrument was used to assess all measures. …

Combining Faculty, Instructional Design, And Library Services To Provide Students A Framework For Information Evaluation, Linda Leake, Samantha Mcclellan

Kentucky Convergence Conference

The creation of the course-embedded Critical Thinking & information Evaluation Module series resulted from the need for undergraduate students to start their academic careers with a framework for evaluating information. Pulling from the Paul-Elder Critical Thinking Framework and focusing abstract information literacy concepts on the commonly-used resources of Wikipedia, Google, and scholarly journal articles, the presenters will delve into module creation to implementation of these modules and discuss the logistics of this process to guide other faculty-librarian-instruction designer collaborations.

Chanticleer | November 12, 2015, Jacksonville State University

Chanticleer

No abstract provided.

Faculty Senate Minutes Nov 12, 2015, Missouri University Of Science And Technology Faculty Senate

Minutes & Agendas

No abstract provided.

The Setonian, November 12, 2015, Seton Hall University

2015

No abstract provided.

Otter Realm, November 12, 2015, California State University, Monterey Bay

The Otter Realm

Dia de los Muertos -- CFA votes yes on strike authorization -- Making cents of your tuition dollar: What you pay at CSUMB -- Dissecting the life of a Biology student -- Startup Hackathon Monterey Bay kicks off Nov. 20 -- Nyob Zoo Xyoo Tshiab: Hmong community celebrates New Years -- Tap into your taste buds: Beer guide Key ingredients -- More gender neutral bathrooms needed on campus -- Letter from AS President: Ema Richardson -- Job search: Are startups for you? -- Shooting to kill? -- Understanding the police procedure: Dave Shaw, Administrative Commander for the Salinas Police Department …

Individual-Level Variation And Higher-Level Interpretations Of Space Use In Wide-Ranging Species: An Albatross Case Study Of Sampling Effects, Sarah Gutowsky, Marty Leonard, Melinda Conners, Scott A. Shaffer, Ian Jonsen

Faculty Publications, Biological Sciences

Marine ecologists and managers need to know the spatial extent of at-sea areas most frequented by the groups of wildlife they study or manage. Defining group-specific ranges and distributions (i.e., space use at the level of species, population, age-class, etc.) can help to identify the source or severity of common or distinct threats among different at-risk groups. In biologging studies, this is accomplished by estimating the space use of a group based on a sample of tracked individuals. A major assumption of these studies is consistency in individual movements among members of a group. The implications of scaling up individual-level …

Effectiveness Of Stevia Rebaudiana Whole Leaf Extract Against The Various Morphological Forms Of Borrelia Burgdorferi In Vitro, Priyanka Annabel Sugantham Theophilus, Maria J. Victoria, Kayla Socarras, Katherine R. Filush, Khusali Gupta, David F. Luecke, Eva Sapi

Biology and Environmental Science Faculty Publications

Lyme disease is a tick-borne multisystemic disease caused by Borrelia burgdorferi. Administering antibiotics is the primary treat-ment for this disease; however, relapse often occurs when antibiotic treatment is discontinued. The reason for relapse remains un-known, but recent studies suggested the possibilities of the presence of antibiotic resistant Borreliapersister cells and biofilms.In this study, we evaluated the effectiveness of whole leaf Stevia extract against B. burgdorferispirochetes, persisters, and bio-film forms in vitro. The susceptibility of the different forms was evaluated by various quantitative techniques in addition to differ-ent microscopy methods. The effectiveness of Stevia was compared to doxycycline, cefoperazone, daptomycin, and …

November Agenda, Wku Graduate Council

Graduate School

Meeting agenda.

Issues In Modern Genomics, Sarah O'Leary-Driscoll

Considerations in Ethics

Breaking News or Science Fiction?

• CRISPR technology, a way to use bacterial proteins to make precise, targeted changes to the DNA of living cells, is under development by multiple scientists.
• The subsequent release of the process and data surrounding it has scientists around the world proclaim that a “new era” of in Molecular Biology has begun.

Effect Of Genetic Background On The Dystrophic Phenotype In Mdx Mice., William D Coley, Laurent Bogdanik, Maria Candida Vila, Qing Yu, Terence A Partridge, Kanneboyina Nagaraju, +12 Additional Authors

Genomics and Precision Medicine Faculty Publications

Genetic background significantly affects phenotype in multiple mouse models of human diseases, including muscular dystrophy. This phenotypic variability is partly attributed to genetic modifiers that regulate the disease process. Studies have demonstrated that introduction of the γ-sarcoglycan null allele onto the DBA/2J background confers a more severe muscular dystrophy phenotype than the original strain, demonstrating the presence of genetic modifier loci in the DBA/2J background. To characterize the phenotype of dystrophin deficiency on the DBA/2J background, we created and phenotyped DBA/2J-congenic Dmdmdx mice (D2-mdx) and compared them to the original, C57BL/10ScSn-Dmdmdx (B10-mdx) model. These strains were compared to their respective …