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2015

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Evaluating Vital Rate Contributions To Greater Sage-Grouse Population Dynamics To Inform Conservation, David K. Dahlgren Nov 2015

Evaluating Vital Rate Contributions To Greater Sage-Grouse Population Dynamics To Inform Conservation, David K. Dahlgren

Wildland Resources Faculty Publications

Species conservation efforts often use short-term studies that fail to identify the vital rates that contribute most to population growth. Although the greater sage-grouse (Centrocercus urophasianus; sage-grouse) is a candidate for protection under the U.S. Endangered Species Act, and is sometimes referred to as an umbrella species in the sagebrush (Artemisia spp.) biome of western North America, the failure of proposed management strategies to focus on key vital rates that may contribute most to achieving population stability remains problematic for sustainable conservation. To address this dilemma, we performed both prospective and retrospective perturbation analyses of a life cycle model based …


Indorsing Infant Immunity: An Argument For Criminalizing Parents' Refusal To Immunize Their Children, Megan Elyse Waterman Nov 2015

Indorsing Infant Immunity: An Argument For Criminalizing Parents' Refusal To Immunize Their Children, Megan Elyse Waterman

Tulsa Law Review

No abstract provided.


Famously Yours...Forever, Otterbein University Theatre And Dance Department Nov 2015

Famously Yours...Forever, Otterbein University Theatre And Dance Department

2015-2016 Season

What if there was a refuge that kept out the darkness and provided companionship with a few kindred souls; a place suspended and exclusive for as long as time goes by?


Faculty Senate Meeting Minutes November 19, 2015, University Of Rhode Island Faculty Senate Nov 2015

Faculty Senate Meeting Minutes November 19, 2015, University Of Rhode Island Faculty Senate

Faculty Senate Meeting Minutes

No abstract provided.


Lipoproteins And Health Outcomes: Cognitive And Physical Function In Older Adults, Marianne Chanti-Ketterl Nov 2015

Lipoproteins And Health Outcomes: Cognitive And Physical Function In Older Adults, Marianne Chanti-Ketterl

USF Tampa Graduate Theses and Dissertations

Cardiovascular health is a major determinant of quality of life and mortality, especially in older adulthood. With the world’s oldest population increasing at expedited rates, challenges from cardiovascular conditions and its implications are spawning. Although it is well known that dyslipidemia may lead to cardiac events, less is known about the effects on cognitive and physical function in older adults. Epidemiological studies show that optimizing current preventive strategies even at older ages may reduce the incidence of cardiovascular comorbidity (e.g. hypertension, stroke) and increase quality of life. Determining the association between lipoproteins and cognitive and functional performance in older adults …


Large Scale Patterns Of Genetic Variation And Differentiation In Sugar Maple From Tropical Central America To Temperate North America, Yalma L. Vargas-Rodriguez, William J. Platt, Lowell E. Urbatsch, David W. Foltz Nov 2015

Large Scale Patterns Of Genetic Variation And Differentiation In Sugar Maple From Tropical Central America To Temperate North America, Yalma L. Vargas-Rodriguez, William J. Platt, Lowell E. Urbatsch, David W. Foltz

Faculty Publications

© 2015 Vargas-Rodriguez et al. Background: Geological events in the latter Cenozoic have influenced the distribution, abundance and genetic structure of tree populations in temperate and tropical North America. The biogeographical history of temperate vegetation that spans large ranges of latitude is complex, involving multiple latitudinal shifts that might have occurred via different migration routes. We determined the regional structuring of genetic variation of sugar maple (Acer saccharum subsp. saccharum) and its only subspecies in tropical America (Acer saccharum subsp. skutchii) using nuclear and chloroplast data. The studied populations span a geographic range from Maine, USA (46°N), to El Progreso, …


Yeast Vacuolar Hops, Regulated By Its Kinase, Exploits Affinities For Acidic Lipids And Rab:Gtp For Membrane Binding And To Catalyze Tethering And Fusion, Amy Orr, William Wickner, Scott F. Rusin, Arminja N. Kettenbach, Michael Zick Nov 2015

Yeast Vacuolar Hops, Regulated By Its Kinase, Exploits Affinities For Acidic Lipids And Rab:Gtp For Membrane Binding And To Catalyze Tethering And Fusion, Amy Orr, William Wickner, Scott F. Rusin, Arminja N. Kettenbach, Michael Zick

Dartmouth Scholarship

Fusion of yeast vacuoles requires the Rab GTPase Ypt7p, four SNAREs (soluble N-ethylmaleimide–sensitive factor attachment protein receptors), the SNARE disassembly chaperones Sec17p/Sec18p, vacuolar lipids, and the Rab-effector complex HOPS (homotypic fusion and vacuole protein sorting). Two HOPS subunits have direct affinity for Ypt7p. Although vacuolar fusion has been reconstituted with purified components, the functional relationships between individual lipids and Ypt7p:GTP have remained unclear. We now report that acidic lipids function with Ypt7p as coreceptors for HOPS, supporting membrane tethering and fusion. After phosphorylation by the vacuolar kinase Yck3p, phospho-HOPS needs both Ypt7p:GTP and acidic lipids to support fusion.


Toward Higher-Order Mass Detection: Influence Of An Adsorbate’S Rotational Inertia And Eccentricity On The Resonant Response Of A Bernoulli-Euler Cantilever Beam, Stephen M. Heinrich, Isabelle Dufour Nov 2015

Toward Higher-Order Mass Detection: Influence Of An Adsorbate’S Rotational Inertia And Eccentricity On The Resonant Response Of A Bernoulli-Euler Cantilever Beam, Stephen M. Heinrich, Isabelle Dufour

Civil and Environmental Engineering Faculty Research and Publications

In this paper a new theoretical model is derived, the results of which permit a detailed examination of how the resonant characteristics of a cantilever are influenced by a particle (adsorbate) attached at an arbitrary position along the beam’s length. Unlike most previous work, the particle need not be small in mass or dimension relative to the beam, and the adsorbate’s geometric characteristics are incorporated into the model via its rotational inertia and eccentricity relative to the beam axis. For the special case in which the adsorbate’s (translational) mass is indeed small, an analytical solution is obtained for the particle-induced …


The Future Of Farming In Capable And Small Hands: The Young Farmer’S Movement In Waterloo Region 1907-1924, Morgan Williams Nov 2015

The Future Of Farming In Capable And Small Hands: The Young Farmer’S Movement In Waterloo Region 1907-1924, Morgan Williams

Laurier Undergraduate Journal of the Arts

No abstract provided.


The Alestle - Vol. 68 No. 12 - 11/19/2015, Southern Illinois University Edwardsville Nov 2015

The Alestle - Vol. 68 No. 12 - 11/19/2015, Southern Illinois University Edwardsville

The Alestle

Vol. 68 No. 12


The Search For A Better Life: One Marine’S Story, Brittany Gaston Nov 2015

The Search For A Better Life: One Marine’S Story, Brittany Gaston

UNH Today Archive

No abstract provided.


The George-Anne, Georgia Southern University Nov 2015

The George-Anne, Georgia Southern University

The George-Anne

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In Vitro And In Vivo Evaluation Of Water-Soluble Iminophosphorane Ruthenium(Ii) Compounds. A Potential Chemotherapeutic Agent For Triple Negative Breast Cancer, Malgorzata Frik, Alberto Martínez, Benelita T. Elie, Oscar Gonzalo, Daniel Ramírez De Mingo, Mercedes Sanaú, Roberto Sánchez-Delgado, Tanmoy Sadhukha, Swayam Prabha, Joe W. Ramos, Isabel Marzo, María Contel Nov 2015

In Vitro And In Vivo Evaluation Of Water-Soluble Iminophosphorane Ruthenium(Ii) Compounds. A Potential Chemotherapeutic Agent For Triple Negative Breast Cancer, Malgorzata Frik, Alberto Martínez, Benelita T. Elie, Oscar Gonzalo, Daniel Ramírez De Mingo, Mercedes Sanaú, Roberto Sánchez-Delgado, Tanmoy Sadhukha, Swayam Prabha, Joe W. Ramos, Isabel Marzo, María Contel

Publications and Research

A series of organometallic ruthenium(II) complexes containing iminophosphorane ligands have been synthesized and characterized. Cationic compounds with chloride as counterion are soluble in water (70–100 mg/mL). Most compounds (especially highly water-soluble 2) are more cytotoxic to a number of human cancer cell lines than cisplatin. Initial mechanistic studies indicate that the cell death type for these compounds is mainly through canonical or caspase-dependent apoptosis, nondependent on p53, and that the compounds do not interact with DNA or inhibit protease cathepsin B. In vivo experiments of 2 on MDA-MB-231 xenografts in NOD.CB17-Prkdc SCID/J mice showed an impressive tumor reduction (shrinkage) of …


Collaborative Care For Depression In Primary Care, Amy J. Schwarzenbart Nov 2015

Collaborative Care For Depression In Primary Care, Amy J. Schwarzenbart

DNP and Student Works

Improvements in symptom recognition and treatment of depression can be improved through collaborative care. Collaboration of both primary care provider and behavioral health providers can help patients with depression obtain high quality and effective treatment in the primary care clinics. The quality improvement practice was to improve the coordination and collaboration of care, access to services, and referral to behavioral health providers.


Vista: November 19, 2015, University Of San Diego Nov 2015

Vista: November 19, 2015, University Of San Diego

USD Vista (1965-)

No abstract provided.


Anticancer Activity Of Some Boronic Acid Arylidene Heterocycles, Joy Kim Nov 2015

Anticancer Activity Of Some Boronic Acid Arylidene Heterocycles, Joy Kim

Honors Theses

This research was done in order to investigate the anticancer activity of boronic acid arylidene heterocycles. Boronic acid, heterocycles, and aryl compounds have all independently exhibited various anti-microbial properties and have shown potential to be used in pharmaceuticals for the treatment of viruses and cancers. Using a one-step protocol developed by Dr. Murray, several different arylheterocyclic compounds were combined with an arylboronic acid to synthesize novel compounds. These were then tested for their anti-cancer activity on glioblastoma brain cancer cells. Although varied in potency, all had some amount of anti-cellular effect on the cancer cells. This is only the start …


A Multiscale Systems Model For Advancement Of A New Line Of Therapy For Osteoporosis, Rena J. Eudy Nov 2015

A Multiscale Systems Model For Advancement Of A New Line Of Therapy For Osteoporosis, Rena J. Eudy

Doctoral Dissertations

The osteocyte is a load-sensing bone cell, which plays a pivotal role in the bone modeling process. This process is highly regulated by feedback control and poorly described by isolated in vivo or in vitro experiments. In silico systems models present a way by which experimental and clinical data can be integrated in a mathematical framework so that physiology, pharmacology and disease progression as it relates to bone health, at the level of cell signaling networks up to the tissue level, can can be better understood. The Multiscale Systems Pharmacology Model presented here began as an endeavor to link biological …


The Parthenon, November 19, 2015, Jocelyn Gibson Nov 2015

The Parthenon, November 19, 2015, Jocelyn Gibson

The Parthenon

The Parthenon, Marshall University’s student newspaper, was published by students Monday through Friday during the regular semester and weekly on Thursdays during the summer. Due to budgetary constraints, beginning with the 2015 Fall semester, the newspaper is only published four days a week. There is no issue on Mondays, physical issues are printed on Tuesdays and Fridays, and online issues only are published on Wednesdays and Thursdays. The editorial staff is responsible for the news and the editorial content.


In Vacuo Fabrication And Electronic Structure Characterization Of Atomic Layer Deposition Thin Films, Michael Schaefer Nov 2015

In Vacuo Fabrication And Electronic Structure Characterization Of Atomic Layer Deposition Thin Films, Michael Schaefer

USF Tampa Graduate Theses and Dissertations

Improvement of novel electronic devices is possible by tailor-designing the electronic structure at device interfaces. Common problems observed at interfaces are related to unwanted band alignment caused by the chemical diversity of interface partners, influencing device performance negatively. One way to address this problem is by introducing ultra-thin interfacial dipole layers, steering the band alignment in a desired direction. The requirements are strict in terms of thickness, conformity and low density of defects, making sophisticated deposition techniques necessary. Atomic layer deposition (ALD) with its Ångstrom-precise thickness control can fulfill those requirements.

The work presented here encompasses the implementation of an …


Characterization Of Two Novel Gene Regulatory Systems In The Zoonotic Bacterium Bartonella Henselae, Nhan Tu Nov 2015

Characterization Of Two Novel Gene Regulatory Systems In The Zoonotic Bacterium Bartonella Henselae, Nhan Tu

USF Tampa Graduate Theses and Dissertations

The genus Bartonella contains Gram-negative arthropod-borne bacteria that are found in many small animal reservoirs and are capable of causing human disease. Bacteria utilize a general stress response system to combat stresses from their surrounding environments. In α-proteobacteria, the general stress response system uses an alternate σ factor as the main regulator and incorporates it with a two-component system into a unique system. Our study identifies the general stress response system in the α-proteobacterium, Bartonella henselae, where the gene synteny is conserved and both the PhyR and alternate σ factor have similar sequence and domain structures with other α-proteobacteria. …


Mass Spectrometry-Based Investigation Of App-Dependent Mechanisms In Neurodegeneration, Dale Chaput Nov 2015

Mass Spectrometry-Based Investigation Of App-Dependent Mechanisms In Neurodegeneration, Dale Chaput

USF Tampa Graduate Theses and Dissertations

Alzheimer’s disease (AD) is the most prevalent form of dementia affecting the elderly, and as the aging population increases the social and economic burden of AD grows substantially. Pathological hallmarks of AD include the accumulation of extracellular amyloid plaques and intracellular neurofibrillary tangles (NFTs), as well as significant neuron loss. Amyloid plaques consist of aggregated amyloid beta (Aβ) peptide, which is generated from the proteolytic processing of amyloid precursor protein (APP) in addition to several other peptides. While the processing of APP has been characterized, its primary physiological function and its involvement in AD pathology are poorly understood. Developing a …


Engaging Overqualified Employees: The Role Of Job And Nonwork Crafting, Soner Dumani Nov 2015

Engaging Overqualified Employees: The Role Of Job And Nonwork Crafting, Soner Dumani

USF Tampa Graduate Theses and Dissertations

The present study examined the relationship between perceived overqualification and work engagement through basic need satisfaction at work and further incorporated job crafting and nonwork crafting to understand the indirect role of need satisfaction. In study 1, a new measure for targeted nonwork crafting was developed and validated. The final scale provided adequate reliability and validity evidence, and predicted life satisfaction and job satisfaction above and beyond the measures of intrinsic motivation and recovery experiences. The main study included a total of 321 full-time employees who had been working in their current job for at least 3 months and represented …


A Comparative Analysis Of Portable X-Ray Fluorescence Spectrometry And Stable Isotopes In Assessing Ancient Coastal Peruvian Diets, Theresa Jane Gilbertson Nov 2015

A Comparative Analysis Of Portable X-Ray Fluorescence Spectrometry And Stable Isotopes In Assessing Ancient Coastal Peruvian Diets, Theresa Jane Gilbertson

USF Tampa Graduate Theses and Dissertations

This dissertation explores a cross-cultural analysis of the dietary signatures of four coastal cultures of prehistoric Peru. A combination of elemental analysis based on portable x-ray fluorescence spectrometry (pXRF), testing trace elements presented in 209 individuals’ skulls representing the Nazca (38), Cañete (33), Lima (40), and Moche (98) valleys and/or cultures of the first millennium AD, is weighed in conjunction with isotope ratio mass spectrometry (IRMS) to analyze human bone collagen and bone apatite derived from a portion of the individuals represented in the Nazca, Cañete, and Lima cranial samples.

Evidence from the results of both tests are weighed using …


The Efficacy Of Child Parent Relationship Therapy When Conducted In An Online Format On Levels Of Parental Acceptance, Brenna Michele Hicks Nov 2015

The Efficacy Of Child Parent Relationship Therapy When Conducted In An Online Format On Levels Of Parental Acceptance, Brenna Michele Hicks

USF Tampa Graduate Theses and Dissertations

Children’s mental health is a topic of concern, not only in the escalating number of children who meet diagnostic criteria for disorders, but also for the practitioners desiring to treat them effectively. Parental involvement in treatment results in more favorable outcomes with longer treatment gains observed, thus reducing mental health issues.

An additional factor in children’s mental health is the effect of levels of parental acceptance toward the child. Parental acceptance is a positive outcome that has been observed in previous studies conducted with Child-Parent Relationship Therapy (CPRT).

There are many reported barriers to seeking treatment for mental health issues, …


Lanthorn, Vol. 50, No. 25, November 19, 2015, Grand Valley State University Nov 2015

Lanthorn, Vol. 50, No. 25, November 19, 2015, Grand Valley State University

Volume 50, July 13, 2015 - June 6, 2016

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.


Problems With Internet And Library Usage For Secondary School Children, Tom Nolan, Mark Humphrys Nov 2015

Problems With Internet And Library Usage For Secondary School Children, Tom Nolan, Mark Humphrys

The ITB Journal

This research consisted of investigating seven hypotheses using the following components: 1. Observation of forty-three secondary school children using the Internet and the library to complete five tasks. 2. An interview was held with all the participants in the study that was audio taped and subsequently transcribed. 3. An on-line form was constructed so that the students could nominate their favourite educational web sites for each class subject. The participants were given five tasks and had to find the answers using two of the most common forms of information retrieval found in Irish schools, the Internet and the school library. …


Pathfinding In Computer Games, Ross Graham, Hugh Mccabe, Stephen Sheridan Nov 2015

Pathfinding In Computer Games, Ross Graham, Hugh Mccabe, Stephen Sheridan

The ITB Journal

One of the greatest challenges in the design of realistic Artificial Intelligence (AI) in computer games is agent movement. Pathfinding strategies are usually employed as the core of any AI movement system. This report will highlight pathfinding algorithms used presently in games and their shortcomings especially when dealing with real-time pathfinding. With the advances being made in other components, such as physics engines, it is AI that is impeding the next generation of computer games. This report will focus on how machine learning techniques such as Artificial Neural Networks and Genetic Algorithms can be used to enhance an agents ability …


Multiculturalism In Secondary Schools – A Linguistic, Socio-Political & Pedagogic Perspective, Maria Kenneally Nov 2015

Multiculturalism In Secondary Schools – A Linguistic, Socio-Political & Pedagogic Perspective, Maria Kenneally

The ITB Journal

As a modern foreign language lecturer I am fascinated by issues of language, culture and identity. To an extent my interest is compounded by the belief that we Irish are bilingual, English and Gaeilge, - a rich language with a strong oral tradition that has been an integral part of Irish identity. In September 1996 I began work as a secondary teacher in an inner city London school with a high proportion of multilingual and multicultural students. My observations and interactions with pupils at Plumstead Manor proved part of a journey of selfanalysis and self-discovery, and fortified my belief that …


The Process And Problems Of Business Start-Ups, Natasha Evers Nov 2015

The Process And Problems Of Business Start-Ups, Natasha Evers

The ITB Journal

“… there is little known about the initial phases of the process (of entrepreneurship). The conception, birth and early development of new ventures are very much an uncharted territory”. (Reynolds and White, 1997:1). This paper sets out to examine the process and problems encountered by new business start-ups. A didactic overview, based on past and current literature in the field, identifies the most common theoretical frameworks frequenting the academic literature and assesses their contribution to explaining and understanding the Process and Problems of New Venture Creation. The founding of a new organisation is not instantaneous and the process is a …


The Johnsonian November 18, 2015, Winthrop University Nov 2015

The Johnsonian November 18, 2015, Winthrop University

The Johnsonian 2010-2019

The Johnsonian is the weekly student newspaper of Winthrop University. It is published during fall and spring semesters with the exception of university holidays and exam periods. We have proudly served the Winthrop and Rock Hill community since 1923.