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Systemic Corruption In An Advanced Welfare State: Lessons From The Québec Charbonneau Inquiry, Denis Saint-Martin

Osgoode Legal Studies Research Paper Series

The Quiet Revolution in the 1960s propelled the province of Québec onto the path of greater social justice and better government. But as the evidence exposed at the Charbonneau inquiry makes clear, this did not make systemic corruption disappear from the construction sector. Rather, it adapted to its new institutional environment and was significantly shaped by the incentives structure it provided. The patterns of corruption emerging from the Charbonneau inquiry bear the imprint of the so-called “Québec model” inherited from the Quiet Revolution in at least three ways: (i) in the economic nationalism that made public policies partial towards French-speaking …

Regulating Water And War In Iraq: A Dangerous Dark Side Of New Governance, Tracey Leigh Dowdeswell, Patricia Hania

Osgoode Legal Studies Research Paper Series

In the legal scholarship, the 'new governance' mode of governance advances an administrative arrangement where decision-making is shared amongst a range of actors, both public and private. The flexible, responsive, and collaborative governance orientation is intended to counter the ill effects of a coercive, top-down, state-centric, command- and-control approach to governance. Critics contend the new governance framework can displace the interests of local communities, disempower individuals, and dislodge basic human rights. The U.S. military has adopted such an adaptive approach in its own governance structure, which in this article is referred to as: the new governance "mentality." This mentality of …

“Contagious Co-Motion”: Student Voices On Being Change Agents, Vicki L. Reitenauer, Tetiana Korzun, Kimberly Lane, Melinda Joy Roberts

Women, Gender, and Sexuality Studies Faculty Publications and Presentations

Designed in response to students’ requests for a capstone where they could form their own individual partnerships in the communities of their choosing, Effective Change Agent offers a structure for community-based learning that allows for high levels of student choice-making and agency. In this article, the authors describe the course; connect it to literature on grassroots change-making, integrative learning, and service-learning; and, through the inclusion of student authors, allow the sharing of insights in the students’ own voices.

Transit And Economic Resilience, Arthur C. Nelson, Matt Miller, Joanna P. Ganning, Philip Stoker, Jenny H. Liu, Reid Ewing

Urban Studies and Planning Faculty Publications and Presentations

Do fixed-guideway transit systems facilitate resilience with metropolitan areas? There is little literature making this connection theoretically and none testing it empirically. This paper helps close this gap in both respects. In evaluating metropolitan areas with light rail transit systems the authors find evidence that transit corridors on the whole performed better than control corridors during the recovery period of two recessions: that of the early 2000s and the so-called Great Recession. In particular, during the Great Recession transit corridors outperformed control corridors among many economic sectors. Outcomes were more impressive during recoveries from both the recession of the early …

Three Hundred Nos: An Empirical Analysis Of The First 300+ Denials Of Institution For Inter Partes And Covered Business Method Patent Reviews Prior To In Re Cuozzo Speed Technologies, Llc, 14 J. Marshall Rev. Intell. Prop. L. 112 (2015), Jarrad Wood, Jonathan Stroud

UIC Review of Intellectual Property Law

Tasked in 2011 with creating powerful new patent review trial regimes, the U.S. Patent and Trademark Office—through the efforts of their freshly empowered quasi-judicial body, the Patent Trial and Appeal Board—set to creating a fast-paced trial with limited discovery and concentrated efficiency. For two years, the proceedings have proved potent, holding unpatentable many of the claims that reached decisions on the merits. Yet a small subsection of petitions never make it past the starting gate, resulting in wasted time and effort on the parts of petitioners—and likely sighs of relief from the rights-holders. The AIA exempted institution decisions from appellate …

Some Speculation About Mirror Neurons And Copyright, 14 J. Marshall Rev. Intell. Prop. L. 410 (2015), Stephen Mcjohn

UIC Review of Intellectual Property Law

Copyright plays a central role in regulating cultural transmission. Authors are given exclusive rights to copy, adapt, distribute, perform and display their works. These rights have limits, most notable fair use and the non-protection of ideas. In setting the bounds of those limits, courts implicitly follow some basic folk psychology. This paper would explore how neuroscience can be used to illuminate and challenge those background assumptions. Copyright law implicitly assumes that literal copying is not necessary for cultural transmission. If there are many ways to express the same idea, then transmission of an idea will not be restricted by prohibiting …

Psychological Perspectives On The Lives Of Transgender Individuals: A Review Of The Literature, Kaitlyn N. Fritz

Honors Capstones

Transgender people as a whole suffer from social invisibility, as the general public is often misinformed about them. Because of the misinformation and ignorance surrounding public opinion of transgender people, it is difficult to conduct psychological studies involving this population. The purpose for this review is to shed some light on how the lives of transgender peoples actually are. The main areas that will be addressed in this review include tracking how transgenderism has been viewed from a clinical psychology perspective in the current and past editions of the Diagnostic and Statistical Manual, how transgender people face transphobia and are …

Livd: Issue 15.1: "Oh, Sherrie", Portland State University. School Of Art + Design

LIVD

Layout, imagery, and editing: Meredith James

Issue 15.1 includes contributions responding to the following prompt: Sherrie Levine. Contributors respond to the various ways Levine’s work has influenced our concept of art, design, self, and issues still central to the lives of women. Topically, the authors vary in their responses, some more direct – as in Nicole Dyar’s social criticism on the appropriation and replication of women’s identities (can an authentic woman exist in contemporary digital culture?) – while others remain more loosely / conceptually related. Sarah McCoy rectifies a noticeable gap in graphic design history, that of early colonial women …

Bulletin: General Catalog Issue 2015-2016, Portland State University

Bulletin & Curriculum Change Documents

Volume 1 is available via the Download option, Volume 2 is available in the Additional Files below

Curriculum Change 2015-2016, Portland State University

Bulletin & Curriculum Change Documents

No abstract provided.

The Relationship Between The Effects Of Rape, Posttraumatic Stress Disorder, Complex Trauma, And Post-Attack Victim-Perpetrator Interaction In Female College Students, Stephanie Christine Bell

Electronic Theses and Dissertations

The purpose of this study was to assess for effects of rape that are specific to women attending college and for relationships between the effects of rape, Posttraumatic Stress Disorder, previous trauma, complex trauma, and post-attack victim-perpetrator interaction to fill gaps in the literature around these issues. The survey was distributed to all female undergraduates at the main campus of a large, public university in the south (N ≈ 8,400). The sample consisted of 463 women (response rate = 5.5%). The majority of participants were between the ages of 18-22, Caucasian, lived off-campus, and with roommates. Participants received an e-mail …

China's Obligation To Conduct Transboundary Environmental Impact Assessment (Teia) In Utilizing Its Shared Water Resources, Nadia Sanchez Castillo, Yongmin Bian

Natural Resources Journal

New water development projects in China threaten the environment of international rivers. Chinese law, however, does not require developers to assess the effects of proposed projects on the environment outside China’s borders. Nevertheless, examples of transboundary cooperation and international agreements provide a basic legal foundation that allows China to implement transboundary environmental impact assessments (TEIA) as a standard practice. This article explores China’s customary law obligation to conduct TEIA by examining relevant treaties and instances of joint action. The article finds that a basic legal structure is already in place to support carrying out environmental impact assessments in a transboundary …

Pocket Monsters And Pirate Treasure: Fantasy And Social Platforms In The 21st Century, Jacob Waalk

Electronic Theses and Dissertations

POCKET MONSTERS AND PIRATE TREASURE: FANTASY AND SOCIAL PLATFORMS IN THE 21ST CENTURY is an anthropology project examining media, fantasy, ideology, and social groups in order to build a better foundation for the ways in which economic and social changes influence social networking, popular media, and values by using the anime-manga subculture as an example. The thesis draws from three major theorists: Thomas LaMarre, Anne Allison, and Ian Condry as well as major anthropological theorists such as Pierre Bourdieu. As an ethnography, the project was split into two sections: one consisting of interviews with eight anime-manga subculture participants drawn primarily …

The Effects Of Clinorotation In The Host Plant, Medicago Truncatula, And Its Microbial Symbionts, Ariel Dauzart

Electronic Theses and Dissertations

The aim of this research was to understand mutualistic relationships between plants and endophytic microbes under the influence of an altered gravity vector. Understanding the outcome of the plant-microbe symbiosis in altered gravity is vital to developing life support systems for long distance space travel and colonization of other planets. This research utilized the model tripartite relationship among Medicago truncatula–Sinorhizobium meliloti–Rhizophagus irregularis. Plants were inoculated with rhizobial bacteria (S. meliloti), arbuscular mycorrhizal fungi (R. irregularis), both microbes, or none (microbial control), and placed on a rotating clinostat for 28 d. Vertical and horizontal static controls were also performed. Plant development …

Progress Toward The Total Synthesis Of The Natural Product Herbicide Ascaulitoxin Aglycone, Jeffery Brian Morgan

Electronic Theses and Dissertations

Ascaulitoxin aglycone is a structurally unique bis-amino acid isolated from the fungal species Ascochyta caulina, with herbicidal activity against Chenopodium album. Ascaulitoxin aglycone's potent herbicidal activity coupled with an unknown but novel mechanism of action makes it a perfect candidate for further study in the pursuit of new natural product herbicides. This dissertation research will illustrate three synthetic strategies towards the total synthesis of ascaulitoxin aglycone from chiral pool building blocks. Strategy 1 invokes the use of the Henry reaction as a key step for the construction of the central C4-C5 cis-aminohydroxy group, which was moderately successful, but abandoned in …

A Stepping Stone Toward Companion Animal Protection Through Compensation, Zachary Paterick, Timothy Paterick, Sandy Sanbar

Animal Law Review

Despite the fact that many Americans view their companion animals as part of the family, the law treats companion animals as personal property. The courts have viewed companion animals as property for over 200 years, however, this precedent no longer adequately accounts for the important role companion animals play in modern day lives, and no longer appropriately compensates for the true value the animal has to the owner. A modified investment approach, stemming from wrongful death precedent, provides both a qualitative and quantitative approach to adequately measure the compan-ionship value these animals have to humans. While courts have entertained various …

Diagnostic Performance Of Breast Mri In The Evaluation Of Contralateral Breast In Patients With Diagnosed Breast Cancer, Shaista Afzal Saeed, Imrana Masroor, Madiha Beg, Romana Idress

Department of Radiology

AIMS: The purpose of our study was to evaluate the diagnostic performance of breast magnetic resonance imaging (MRI) in the evaluation of contralateral breast in patients with diagnosed breast cancer. A secondary objective was to determine accuracy of breast MRI in diagnosing multi-focal and multicentric lesions in the ipsilateral breast.MATERIALS AND Methods: Using a non-probability convenience sampling technique, patients with histopathologically diagnosed breast cancer with MRI of breast performed to exclude additional lesions were included. MRI findings were correlated with histopathology. In addition, follow-up imaging with mammography and ultrasound was also assessed for establishing stability of negative findings and for …

Optimization And Structural Characterization Of Dimethyl Trisulfide (Dmts) Oxidation Product, Laura Dirks, Brian Peterson, Benjamin Walter

The Journal of Undergraduate Research

Cyanide poisoning is a public concern, and there are many shortfalls in current cyanide treatments. Dimethyl trisulfide (DMTS) is a cyanide antidote candidate that overcomes these shortfalls. Currently, there are limited published reports related to the analysis of DMTS. Therefore, an analytical method to detect and analyze DMTS from a biological matrix is vital for it to become available as a therapeutic agent against cyanide poisoning. The motivation of this project is to develop an HPLC-MS/MS method for analysis of DMTS and its degradation products; however, DMTS is difficult to ionize, a requirement for MS analysis, due to its nonpolar …

Culturally Responsive Teaching In A War-Affected Area: Lesley University In Israel – 1979-2014, Vivien Marcow-Speiser, Samuel Schwartz

Journal of Pedagogy, Pluralism, and Practice

The article begins by assessing the theoretical issues raised in the literature regarding teaching in another culture and, in particular, teaching in a conflict zone. It then goes on to describe the specific conditions under which Lesley University’s program operated in Israel. A large portion of the article outlines the teaching and community outreach activities of Lesley University in Israel since 1979, and how they met the challenges of culturally-responsive teaching in a war-affected area, focusing on its work training therapists, educators and community activists, organizing conferences and launching community outreach programs. The article discusses issues such as preparing faculty …

Exploring Femoroacetabular Impingement: An Examination Of The Evolution Of The Disease And Implications For The Development Of Osteoarthritis, Raghav Badrinath

Yale Medicine Thesis Digital Library

EXPLORING FEMOROACETABULAR IMPINGEMENT AND ITS IMPLICATIONS FOR THE DEVELOPMENT OF OSTEOARTHRITIS. Raghav Badrinath, Daniel R. Cooperman. Section of Pediatric Orthopedics, Department of Orthopedics and Rehabilitation, Yale University, School of Medicine, New Haven, CT

Femoroacetabular impingement (FAI) has been recently elucidated as an explanation for cases of hip osteoarthritis (OA) that were previously categorized as "idiopathic". We examine three questions related to FAI - the antiquity of the cam deformity, the role of overcoverage in hip osteoarthritis and the mechanism of impingement with acetabular retroversion.

To examine the antiquity of the cam deformity, we performed proximal femoral measurements on 175 femora …

Autophagy Over The Lifespan: Using Fetal, Stem Cell, And Adult Retinal Pigment Epithelium (Rpe) Cultures To Model Amd Pathogenesis, Katherine Jean Davis

Yale Medicine Thesis Digital Library

Purpose: Dysfunctional autophagy in the retinal pigment epithelium (RPE) has been implicated as a therapeutic target in age-related macular degeneration (AMD). To explore how RPE autophagy changes over the lifespan and in response to phagocytosis of photoreceptor outer segments (POS), we compared stem cell-derived RPE (hESC-RPE, iPS-RPE), human fetal RPE (hfRPE), the ARPE-19 cell line, and adult RPE (ad-RPE).

Methods: RPE was cultured from 16-week human fetuses and cadaveric eyes. Stem cell- derived RPE was prepared from human embryonic stem cells (hESC-RPE) and induced pluripotent stem cells (iPS-RPE). LC3 conversion (immunoblotting) and changes in autophagy-related gene expression (qRT2-PCR) were used …

The Heterotaxy Candidate Gene, Tmem195, Regulates Nuclear Localization Of Beta-Catenin, Anna Ruth Duncan

Yale Medicine Thesis Digital Library

Congenital heart disease (CHD) affects 1 in every 130 newborns and is the leading cause of infant mortality (2). Heterotaxy (Htx), a disorder of left-right (LR) development, commonly leads to CHD. Despite aggressive surgical management, patients with Htx have poor survival rates and severe morbidity due to their complex CHD. Many of the genetic causes of Htx remain undefined, however, a recent genetic analysis of Htx patients identified a single mutant allele in the novel candidate gene, TMEM195 (3). TMEM195 is an alkylglyercol monooxygenase that cleaves ether lipids, but neither its molecular target nor its role in development has been …

Tartrate-Resistant Acid Phosphatase: Prognosis In Colorectal Cancer And The M1/M2 Distinction., Chi-Joan How

Yale Medicine Thesis Digital Library

Recent research has indicated that separate populations of macrophages are

associated with differing outcomes in cancer survival. In our study, we examine

macrophage expression of tartrate resistant acid phosphatase (TRAP) and its effect on

survival in colon cancer. Immunohistochemical analysis on colorectal adenocarcinomas

confirmed macrophage expression of TRAP. Co-localization of TRAP with CD68, a pan

macrophage marker, revealed that TRAP is present in some but not all subpopulations of

macrophages. Further co-localization of TRAP with CD163, an M2 marker, revealed that

TRAP is expressed by both M2 and non-M2 macrophages. TRAP expression was then

measured using the AQUA method of …

Novel Mechanisms Of Trophoblast Responses To Antiphospholipid Antibodies And Therapeutics In Obstetric Antiphospholipid Syndrome, Stefan Mathias Gysler

Yale Medicine Thesis Digital Library

Obstetric antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by circulating antiphospholipid antibodies (aPL) and an increased risk of recurrent pregnancy loss and preeclampsia. Current treatments, such as low molecular weight heparin (LMWH) may maintain pregnancy but do not reduce the risk of these late gestational complications. aPL trigger placental inflammation by activating trophoblast Toll-like receptor 4 (TLR4), leading to cytokine production. Since some microRNAs (miRs) regulate TLR responses, this study sought to determine the functional role of aPL-induced miR expression in regulating trophoblast inflammation. Since vitamin D deficiency is common in APS patients, the effect of vitamin D …

Neuropsychological Testing Impairment In Acute Hiv And The Effects Of Immediate Antiretroviral Therapy, Idil Kore

Yale Medicine Thesis Digital Library

Acute HIV infection (AHI) is accompanied by central nervous system infection and immune activation. We investigated baseline predictors of neuropsychological (NP) performance in Thai participants with AHI and the effect of antiretroviral therapy (ART) on domains of functioning known to be affected by HIV.

36 participants with AHI (89% male, median age of 28 years, median time since HIV exposure of 19 days) were evaluated at baseline and 3 and 6 months after ART. Performance on the Grooved Pegboard test (GP), Color Trails 1 & 2 (CT1, CT2), and Trails Making Test A (TM) were standardized to 251 age and …

Evaluating Targeted And Immunomodulatory Therapies For Melanoma In A Genetically Engineered Mouse Melanoma Model, Billy Lockhart

Yale Medicine Thesis Digital Library

Melanoma therapy has changed rapidly due to the emergence of new therapies: MAPK-pathway targeted drugs and immunomodulatory agents. Given the relative success of these new individual drugs, this work set out to evaluate and develop effective melanoma treatments using combination therapies in a preclinical mouse melanoma models. Therapies tested include BRAF kinase inhibition in combination with: immune checkpoint inhibitors anti-CTLA4, anti-PDL1, and with the topical TLR7/8 agonist imiquimod. Drugs efficacies were tested in established melanomas in a conditional inducible mouse melanoma model based on activation of Braf and beta catenin and loss of Pten. 
BRAF inhibition in combination with anti-CTLA-4/anti-PD-L1 …

Correlates Of Cocaine Use In Pregnancy, Regina Marie Melendez

Yale Medicine Thesis Digital Library

Background: Cocaine is the third most commonly used illicit substance in pregnancy. Few studies exist to specifically look for correlates of cocaine use in pregnancy.

Objective: To identify correlates of frequency of cocaine use in pregnancy

Methods: We analyzed retrospective data from 50 postpartum women with a history of cocaine use or dependence who participated in a treatment trial for postpartum cocaine use. Study variables included severity of baseline cocaine use, age of onset of use, comorbid mental illness, poly-substance use, trauma and social support history. Data were analyzed using GLMM Negative Binomial Regression.

Results: The strongest correlate of cocaine …

Symptoms Of Depression Are Linked To Subsequent Recurrent Chest Pain In Patients Admitted To An Emergency Department Chest Pain Unit., Summer Paradise

Yale Medicine Thesis Digital Library

SYMPTOMS OF DEPRESSION ARE LINKED TO SUBSEQUENT RECURRENT CHEST PAIN IN PATIENTS ADMITTED TO AN EMERGENCY DEPARTMENT CHEST PAIN UNIT. Summer A. Paradise, Matt Naftilan, James Dziura, Aini Jelani, Morgan Soffler and Basmah Safdar. Department of Emergency Medicine, Yale University, School of Medicine, New Haven, CT.

Prior studies suggest a high prevalence of depression in patients with chest pain, but few US studies have examined depression and recurrent chest pain in the emergency room setting. This study sought to compare symptoms of depression, socio-demographic features, and clinical features between low-moderate-risk emergency room (ER) chest pain center (CPC) patients with and …

A 35-Year Analysis Of Gender Trends In Radiology Authorship, Crystal Piper

Yale Medicine Thesis Digital Library

Purpose: To describe trends in authorship among female radiologists, compared to their overall representation in radiology, and to investigate the tendency of female first authors to publish with female last authors.

Material and Methods: We collected and analyzed data on gender of first and last authors for all original research and guest editorial articles from three main radiology journals - Radiology, American Journal of Roentgenology (AJR), and Academic Radiology. We restricted our analysis to authors with M.D. (medical doctorate) degrees from academic institutions within the United States. Manuscript data were collected for years 1978, 1998, 2008, and 2013. We obtained …

Tissue Engineering The Neural Retina With Human Embryonic Stem Cells: Exploring The Role Of The Retinal Pigment Epithelium, Yu Cheng Peter Zhao

Yale Medicine Thesis Digital Library

In order to restore vision in the late stages of retinal degeneration, it is necessary to address loss of cells from both the retinal pigment epithelium (RPE) and the neural retina. As a step towards generating neural retinal tissue for translational studies, we evaluated a biodegradable polymer scaffold as a three-dimensional vehicle for the directed differentiation of H9 human embryonic stem cells (H9-hESC) into neural retina. Polymer scaffolds were electrospun from 14% w/v polycaprolactone (PCL), approximated the thickness of native neural retina, and consisted of loose, randomly oriented fibers of subcellular diameter. H9-hESC were seeded to PCL scaffolds, cultured in …