Digital Commons Network^™

A 35-Year Analysis Of Gender Trends In Radiology Authorship, Crystal Piper

Yale Medicine Thesis Digital Library

Purpose: To describe trends in authorship among female radiologists, compared to their overall representation in radiology, and to investigate the tendency of female first authors to publish with female last authors.

Material and Methods: We collected and analyzed data on gender of first and last authors for all original research and guest editorial articles from three main radiology journals - Radiology, American Journal of Roentgenology (AJR), and Academic Radiology. We restricted our analysis to authors with M.D. (medical doctorate) degrees from academic institutions within the United States. Manuscript data were collected for years 1978, 1998, 2008, and 2013. We obtained …

Tissue Engineering The Neural Retina With Human Embryonic Stem Cells: Exploring The Role Of The Retinal Pigment Epithelium, Yu Cheng Peter Zhao

Yale Medicine Thesis Digital Library

In order to restore vision in the late stages of retinal degeneration, it is necessary to address loss of cells from both the retinal pigment epithelium (RPE) and the neural retina. As a step towards generating neural retinal tissue for translational studies, we evaluated a biodegradable polymer scaffold as a three-dimensional vehicle for the directed differentiation of H9 human embryonic stem cells (H9-hESC) into neural retina. Polymer scaffolds were electrospun from 14% w/v polycaprolactone (PCL), approximated the thickness of native neural retina, and consisted of loose, randomly oriented fibers of subcellular diameter. H9-hESC were seeded to PCL scaffolds, cultured in …

Learning From Experience: A Critical, Collective Process Following International Short-Term Mission Travel, Nancy Vigander Winfrey

Educational Studies Dissertations

This qualitative dissertation seeks to explore the impact of short-term mission (STM) travel on American Christian volunteers, leveraging the small group structure already present in many churches. Using a participatory action research approach, small groups from two different Protestant churches engaged in cycles of dialogue, reflection and action. The group process was framed by Habermas’ concept of communicative space with emphasis on emotional knowing, cognitive reasoning, and creative expression. Data were collected from session recordings, written documents and process field notes. Content and process analyses were guided by transformative and situated learning theories. Findings were unique to each congregational group, …

Gender, Self-Efficacy, And Mathematics Achievement: An Analysis Of Fourth Grade And Eighth Grade Timss Data From The United States, Jennifer Anne Evans

Educational Studies Dissertations

It has been argued by some that boys are inherently better in mathematics than girls (Halpern, 2012; Summers, 2005). However, according to international assessments such as the Trends in Mathematics and Science Study’s (TIMSS) and Program for International Student Assessment (PISA), boys do not always outperform girls in mathematics (Mullis, Martin, Foy, & Arora, 2012; OECD, 2014). As such, something other than biology might better explain variations in mathematics performance. One explanation may be self-efficacy, a label used to describe judgments people make about themselves in terms of whether or not they have the capability of doing something (Bandura, 1995; …

Parents' Expressed Educational Dissent In Middle School Education Systems, Marjorie M. Buckner

Theses and Dissertations--Communication

Hoy and Miskel (2008) and Weick (1976) conceptualize schools as organizational systems of which parents comprise part of the organization. Specifically, parent involvement includes such behaviors as assisting students with homework, participating in policy decisions, and providing feedback (Barge & Loges, 2003). Parent involvement is largely championed in K12 education and particularly in middle schools (e.g., Coalition of Essential Schools, 1993; Texas Education Agency, 1991). In fact, both parents and teachers value building positive parent-teacher relationships (Kalin & Steh, 2010) and may communicate regarding a variety of topics including student academic performance, classroom behavior, preparation, hostile peer interactions, and health …

Examining Peer Perceptions Of Humorous Communication In The College Classroom, David Chanson Davenport

Theses and Dissertations--Communication

The majority of instructional communication literature has historically focused on the positive outcomes of incorporating humor into the classroom. However, despite the clearly documented instructional benefits of humorous communication, the literature tends to focus solely on instructor-enacted humor. However, humor is not a homogenous concept; therefore, it is imperative to examine it from a number of contexts, including student-enacted humor. Although the Instructional Humor Processing Theory (IHPT) has made a number of theoretical advances in exploring humorous communication in the classroom, it still lacks adequate explanatory power, particularly when examining student-enacted humor. Thus, four expansions to IHPT …

Gliopathy Of Demyelinating And Non-Demyelinating Strains Of Mouse Hepatitis Virus, Lawrence Charles Kenyon, Kaushiki Biswas, Kenneth Shindler, Manasi Nabar, Marjorie Stout, Susan T. Hingley, Judith B. Grinspan, Jayasri Das Sarma

PCOM Scholarly Works

Demyelination in the central nervous system induced by neurovirulent strains of Mouse Hepatitis Virus (MHV) is mediated by the viral spike glycoprotein, but it is not clear whether the mechanism of this disease pathology involves direct viral infection of oligodendrocytes. Detailed studies of glial cell tropism of MHV are presented, demonstrating that direct MHV infection of oligodendrocytes differs between demyelinating (RSA59) and non-demyelinating (RSMHV2) viral strains both in vitro and in vivo. Our results indicate that direct injury of mature oligodendrocytes is an important mechanism of virus-induced demyelination. In vivo, RSA59 infection was identified in spinal cord gray and white …

The Relationship Of Hispanic Ethnicity, Drug Use, And Bullying With Suicidal Ideation Among Adolescent Females In The 2013 Youth Risk Behavior Surveillance Survey, Erin Camp

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

BACKGROUND: There is little research on the relationship of Hispanic ethnicity, drug use, and bully victimization with suicidal ideation among adolescent females. This study investigates all components and their association with suicidal ideation using the 2013 Youth Risk Behavior Surveillance Survey (YRBSS).

METHODS: Participants were 6,621 adolescent females who completed a self-administered questionnaire (YRBSS). Students answered a series of questions regarding unintentional injuries and violence and alcohol and other drug use.

RESULTS: Results indicated that there was an association between drug use, bully victimization, and suicidal ideation. Bivariate analyses using chi-square tests showed the relationships between these risk factors and …

A Story Of A Birth And A Funeral: A Rhetorical Analysis Of Windsor And Shelby County, Min Kyung Lee

Journal of Law and Policy

No abstract provided.

Healthy You, Lehigh Valley Health Network

Healthy You

No abstract provided.

Dendritic And Langerhans Cells Respond To Aβ Peptides Differently: Implication For Ad Immunotherapy, Jiang Cheng, Xiaoyang Lin, David Morgan, Marcia Gordon, Xi Chen, Zhen-Hai Wang, Hai-Ning Li, Lan-Jie He, Shu-Feng Zhou, Chuanhai Cao

Molecular Pharmacology & Physiology Faculty Publications

Both wild-type and mutated beta-amyloid (Aβ) peptides can elicit an immune response when delivered subcutaneously. However, only mutated forms of Aβ can sensitize dendritic cells when administered intravenously or intraperitoneally. To understand the role of mutation and delivery routes in creating immune responses, and the function of dendritic cells as therapeutic agents, we used fluorescent-conjugated WT Aβ1-40 (WT40) and artificially mutated Aβ1-40 (22W40) peptides to treat dendritic and Langerhans cells from young and/or old mice at different time points. The cell types were analyzed by flow cytometry and confocal microscopy to identify differences in function and antigen presentation, and Luminex …

Survival And Dispersal Of White-Tailed Deer In The Agricultural Landscape Of East-Central Illinois, Charles W. Anderson, Clayton K. Nielsen, Eric M. Schauber

Publications

White-tailed deer (Odocoileus virginianus) are a keystone species throughout their range in North America. The recent presence of diseases such as chronic wasting disease and bovine tuberculosis in Midwestern North America dictates the examination of influences of those diseases on deer populations, and survival and dispersal rates are important parameters when modeling potential disease spread. We quantified survival and dispersal rates of 105 deer in agriculturally-dominated east-central Illinois during 2005-2009. We used Program MARK to estimate rates of annual survival, seasonal survival, and dispersal for fawn, yearling, and adult age-classes. Male and female seasonal (winter/spring [16 Dec–14 May], summer [15 …

Ranging Behavior Of Marsh Rice Rats In A Southern Illinois Wetland Complex, Scott A. Cooney, Eric M. Schauber, Eric Hellgren

Publications

The marsh rice rat (Oryzomys palustris) inhabits wetlands that are often fragmented and isolated by upland cover types. Persistence of marsh rice rat populations and metapopulations likely depends on their ability to enter and traverse the upland matrix, yet basic information, such as home-range size and landcover use patterns, is lacking. Our goal was to quantify home-range size and habitat selection by marsh rice rats in southern Illinois. Between March and November 2011, we radiocollared 21 male rice rats (8 subadults and 13 adults) that were each located 7 to 24 times each via triangulation and homing. We estimated home-range …

Orchid–Pollinator Interactions And Potential Vulnerability To Biological Invasion, Adam D. Chupp, Loretta L. Battaglia, Eric M. Schauber, Sedonia D. Sipes

Publications

Mutualistic relationships between plants and their pollinators have played a major role in the evolution of biodiversity. While the vulnerability of these relationships to environmental change is a major concern, studies often lack a framework for predicting impacts from emerging threats (e.g. biological invasions). The objective of this study was to determine the reliance of Platanthera ciliaris (orange-fringed orchid) on Papilio palamedes (Palamedes swallowtail butterfly) for pollination and the relative availability of alternative pollinators. Recent declines of P. palamedes larval host plants due to laurel wilt disease (LWD) could endanger P. ciliaris populations that rely heavily on this butterfly for …

A Coding Variant In Tmc8 (Ever2) Is Associated With High Risk Hpv Infection And Head And Neck Cancer Risk, Caihua Liang, Karl T. Kelsey, Michael D. Mcclean, Brock C. Christensen, Carmen J. Marsit

Dartmouth Scholarship

HPV infection is a causal agent in many epithelial cancers, yet our understanding of genetic susceptibility to HPV infection and resultant cancer risk is limited. Epidermodysplasia Verruciformis is a rare condition of extreme susceptibility to cutaneous HPV infection primarily attributable to mutations in TMC6 and TMC8. Genetic variation in the TMC6/TMC8 region has been linked to beta-type HPV infection and squamous cell carcinoma of the skin, cervical cancer, HPV persistence and progression to cervical cancer. Here, we have tested the hypothesis that the common TMC8 SNP rs7208422 is associated with high-risk HPV infection and risk of head and neck …

Influence Of Environmental Exposure On Human Epigenetic Regulation, C. J. Marsit

Dartmouth Scholarship

Environmental toxicants can alter epigenetic regulatory features such as DNA methylation and microRNA expression. As the sensitivity of epigenomic regulatory features may be greatest during the in utero period, when critical windows are narrow, and when epigenomic profiles are being set, this review will highlight research focused on that period. I will focus on work in human populations, where the impact of environmental toxicants in utero, including cigarette smoke and toxic trace metals such as arsenic, mercury and manganese, on genome-wide, gene-specific DNA methylation has been assessed. In particular, arsenic is highlighted, as this metalloid has been the focus …

Altered Neurotransmission Prior To Cognitive Decline In Aβpp/Ps1 Mice, A Model Of Alzheimer's Disease, Kevin N. Hascup, Erin R. Hascup

Articles

Indirect evidence supports altered glutamate signaling with Alzheimer's disease, however, it is not known if glutamate neurotransmission is impacted prior to cognitive decline. We examined cognition and glutamate neurotransmission in 2-4 month AβPP/PS1, an Alzheimer's disease model, and age-matched control mice. There were no differences in learning and memory as assessed by Morris water maze. However, in vivo electrochemical measures of potassium-evoked glutamate release in the CA1, but not the CA3 or dentate, was significantly elevated in AβPP/PS1 mice. These data support changes in the glutamatergic system that precedes cognitive decline in a mouse model of Alzheimer's disease.

2015-2016 Southern Illinois University Bulletin Carbondale Campus (Undergraduate Catalog), Southern Illinois University Carbondale

SIU Bulletins and Course Catalogs Archives

No abstract provided.

2015-2016 Southern Illinois University Bulletin Carbondale Campus (Graduate Catalog), Southern Illinois University Carbondale

SIU Bulletins and Course Catalogs Archives

No abstract provided.

Evaluation Of L-Methionine Bioavailability In Nursery Pigs, Jina Lim

Theses and Dissertations--Animal and Food Sciences

DL-Methionine (Met) has been conventionally used in swine diets with assumption of similar bioefficacy with L-Met. However, because L-Met is the form that is utilized by animals for protein synthesis, L-Met could, theoretically, be more available. Four experiments were conducted to evaluate L-Met bioavailability in nursery pigs with 21-day growth trials. A total of 105,105,112 and 84 crossbred pigs were used in Exp. 1, 2, 3 and 4, respectively. Each experiment had a low Met basal diet and 3 levels of the Met sources (DL-Met and L-Met). In addition to the basal diet, supplementation levels were 0.053%, 0.107% and 0.160% …

A Novel Mechanism To Explain Success Of Invasive Herbaceous Species At The Expense Of Natives In Eastern Hardwood Forests, Frank S. Gilliam

Biological Sciences Faculty Research

Among the more intriguing topics in general ecology courses are the symbiotic relationships (the ‘-isms’ as I sometimes present them – mutualism, commensalism, and parasitism). Of these, mutualism is typically the most appealing to students. The scenario that different species can not only co-exist, but can also provide essential resources/services for one another, resonates well with all but the least interested in the course. Ultimately, however, there is also the palpable degree of dismay when they discover that these relationships arise from mutual exploitation, rather than from some benign force of nature. A flip-side of this, in many ways a …

A Study Of Margin Setting In Pattern Recognition :Algorithm, Performance And Application, Yi Wang

Dissertations

Margin setting is a novel supervised learning algorithm for pattern recognition. In this research, we studied margin setting in terms of its algorithm, performance, and application. The algorithm and performance were studied from a new perspective: margin. Margin measures the associated distance from the data to the classification boundaries. Margin is an important design parameter that has a direct impact on the performances of margin setting. The performance impact of margin was comprehensively analyzed in two aspects. First, given the fact that margin setting generates a spherical decision boundary in pattern recognition, we proposed a novel approach that combines margin …

Scalia’S Short Reply To 125 Years Of Plenary Power, Michael Scaperlanda

Oklahoma Law Review

With its plenary power doctrine, the Supreme Court erred by rejecting the universal in favor of the particular. Liberal immigration theorists, on the other hand, make the opposite error by rejecting the particular in favor of the universal. Drawing on classic international law publicists and the Catholic philosophical tradition, this essay argues that the two concepts—the state’s greater duty toward its own citizens (the particular) and equal dignity and worth of all human beings (the universal)—go hand in hand: complementing each other and giving the state a qualified right to limit immigration along with a qualified duty to admit vulnerable …

Louisiana Agriculture Winter, 2015

Louisiana Agriculture

No abstract provided.

Electrocatalytic Reduction Of Co2 At Au Nanoparticle Electrodes: Effects Of Interfacial Chemistry On Reduction Behavior, Evan Andrews, Sai Katla, Challa Kumar, Matthew Patterson, Phillip Sprunger, And John Flake

Faculty Publications

Nanoscale Au electrocatalysts demonstrate the extraordinary ability to reduce CO2 at low overpotentials with high selectivity to CO. Here, we investigate the role of surface chemistry on CO2 reduction behavior using Au25 and 5 nm Au nanoparticles. Onset potentials for CO2 reduction at Au25 nanoparticles in Nafion binders are shifted anodically by 190 mV while the hydrogen evolution reaction is shifted cathodically by 300 mV relative to Au foil. The net effect of this beneficial separation in onset potentials is relatively high Faradayic efficiencies for CO (90% at 0.8 V versus RHE) at high current densities. Experimental results show Faradayic …

Relaxation-Compensated Difference Spin Diffusion Nmr For Detecting 13C-13C Long-Range Correlations In Proteins And Polysaccharides, Tuo Wang, Jonathan K. Williams, Klaus Schmidt-Rohr, Mei Hong

Faculty Publications

© 2014 Springer Science+Business Media Dordrecht. The measurement of long-range distances remains a challenge in solid-state NMR structure determination of biological macromolecules. In 2D and 3D correlation spectra of uniformly 13C-labeled biomolecules, inter-residue, inter-segmental, and intermolecular 13C-13C cross peaks that provide important long-range distance constraints for three-dimensional structures often overlap with short-range cross peaks that only reflect the covalent structure of the molecule. It is therefore desirable to develop new approaches to obtain spectra containing only long-range cross peaks. Here we show that a relaxation-compensated modification of the commonly used 2D 1H-driven spin diffusion (PDSD) experiment allows the clean detection …

Cellulose-Pectin Spatial Contacts Are Inherent To Never-Dried Arabidopsis Primary Cell Walls: Evidence From Solid-State Nuclear Magnetic Resonance, Tuo Wang, Yong Bum Park, Daniel J. Cosgrove, Mei Hong

Faculty Publications

© 2015 American Society of Plant Biologists. All rights reserved. The structural role of pectins in plant primary cell walls is not yet well understood because of the complex and disordered nature of the cell wall polymers. We recently introduced multidimensional solid-state nuclear magnetic resonance spectroscopy to characterize the spatial proximities of wall polysaccharides. The data showed extensive cross peaks between pectins and cellulose in the primary wall of Arabidopsis (Arabidopsis thaliana), indicating subnanometer contacts between the two polysaccharides. This result was unexpected because stable pectin-cellulose interactions are not predicted by in vitro binding assays and prevailing cell wall models. …

Cell Type-Specific Responses To Salinity - The Epidermal Bladder Cell Transcriptome Of Mesembryanthemum Crystallinum, Dong Ha Oh, Bronwyn J. Barkla, Rosario Vera-Estrella, Omar Pantoja, Sang Yeol Lee, Hans J. Bohnert, Maheshi Dassanayake

Faculty Publications

© 2015 New Phytologist Trust. Mesembryanthemum crystallinum (ice plant) exhibits extreme tolerance to salt. Epidermal bladder cells (EBCs), developing on the surface of aerial tissues and specialized in sodium sequestration and other protective functions, are critical for the plant's stress adaptation. We present the first transcriptome analysis of EBCs isolated from intact plants, to investigate cell type-specific responses during plant salt adaptation. We developed a de novo assembled, nonredundant EBC reference transcriptome. Using RNAseq, we compared the expression patterns of the EBC-specific transcriptome between control and salt-treated plants. The EBC reference transcriptome consists of 37 341 transcript-contigs, of which 7% …

Synthesis, Spectroscopic, And In Vitro Investigations Of 2,6-Diiodo-Bodipys With Pdt And Bioimaging Applications, Jaime H. Gibbs, Zehua Zhou, David Kessel, Frank R. Fronczek, Svetlana Pakhomova, M. Graҫa H. Vicente

Faculty Publications

© 2015 Elsevier B.V. All rights reserved. A series of five mono-styryl and their corresponding symmetric di-styryl-2,6-diiodo-BODIPYs containing indolyl, pyrrolyl, thienyl or tri(ethylene glycol)phenyl groups were synthesized using Knoevenagel condensations. The yields for the condensation reactions were improved up to 40% using microwave irradiation (90 °C for 1 h at 400 W) due to lower decomposition of BODIPYs upon prolonged heating. The spectroscopic, structural (including the X-ray of a di-styryl-2,6-diiodo-BODIPY) and in vitro properties of the BODIPYs were investigated. The extension of π-conjugation through the 3,5-dimethyls of the known phototoxic 2,6-diiodo-BODIPY 1 produced bathochromic shifts in the absorption and emission …

Blueberries Improve Glucose Tolerance Without Altering Body Composition In Obese Postmenopausal Mice, Carrie M. Elks, Jennifer D. Terrebonne, Donald K. Ingram, Jacqueline M. Stephens

Faculty Publications

© 2015 The Obesity Society. Objective Metabolic syndrome (MetS) risk increases significantly during menopause and remains elevated postmenopause. Several botanicals, including blueberries (BB), have been shown to delay MetS progression, but few studies have been conducted in postmenopausal animal models. Here, the effects of BB supplementation on obese postmenopausal mice using a chemically induced menopause model were examined. Methods After induction of menopause, mice were fed a high-fat diet or the same diet supplemented with 4% BB powder for 12 weeks. Body weight and body composition were measured, and mice were subjected to glucose and insulin tolerance tests. Serum triglycerides …