Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 19951 - 19980 of 818142

Full-Text Articles in Entire DC Network

Understanding Crystallization Behaviors Of Polyethylene-Derived Vitrimers, Sara Valdez Dec 2025

Understanding Crystallization Behaviors Of Polyethylene-Derived Vitrimers, Sara Valdez

Dissertations

Polyolefins (POs), particularly polyethylene (PE) and polypropylene (PP), are among the most widely utilized polymers globally, valued for their low production costs and favorable mechanical properties stemming from their semicrystalline microstructure. However, their extensive use and improper disposal have raised serious environmental and human health concerns. In response, PO-derived covalent adaptable networks (CANs) have emerged, integrating dynamic chemistries to enable recyclability and sustainable end-of-life strategies. While existing literature has largely focused on novel CAN systems, structure–property relationships, and network rearrangement in relation to thermal transitions (e.g., topological freezing temperature), the influence of network formation on crystallinity and crystallization kinetics remains …


Motivators And Work Role Satisfaction Among A Post-Pandemic Multi-Generational Sports And Entertainment Industry Workforce, Christopher J. Kinnan Dec 2025

Motivators And Work Role Satisfaction Among A Post-Pandemic Multi-Generational Sports And Entertainment Industry Workforce, Christopher J. Kinnan

Dissertations

This quantitative causal-comparative study explored intrinsic and extrinsic motivators and work-role satisfaction among a post-pandemic, multigenerational workforce in the North American sports and entertainment industry. Using an adapted version of the Sports Grounds Safety Authority’s (SGSA, 2022) Evaluation of Systematic Stewarding Challenges instrument, the study analyzed data from 560 participants representing safety, security, and service roles across sports and entertainment venues. The research examined generational differences in motivation, satisfaction, and barriers to retention within the framework of Human Capital Theory, Herzberg’s Two-Factor Theory, and Self-Determination Theory.

Principal component and confirmatory factor analyses verified the reliability and validity of the adapted …


An Examination Of African American Male College Students’ Perceptions Of Academic Engagement, Social Capital, And Success As Members Of Black Greek Letter Organizations On Predominantly White Campuses, Jerid P. Woods Dec 2025

An Examination Of African American Male College Students’ Perceptions Of Academic Engagement, Social Capital, And Success As Members Of Black Greek Letter Organizations On Predominantly White Campuses, Jerid P. Woods

Dissertations

This exploratory qualitative study examines the experiences of Black male students at predominantly White institutions (PWIs) through the lens of Yosso's Cultural Capital framework. It explores how membership in Historically Black Greek Letter Organizations (HBGLOs) shapes academic engagement, development of cultural and social capital, and academic success by leveraging cultural wealth.

Data were collected through semi-structured interviews with ten participants from various HBGLOs, and thematic analysis was used to identify key themes and patterns. Findings highlight that HBGLOs act as vital sources of social, cultural, and academic support, fostering a sense of belonging, promoting academic achievement, and creating leadership opportunities. …


Molecular Design And Engineering Of Luminophores For Aggregation Induced Electrogenerated Chemiluminescence, Jesy Alka Motchaalangaram Dec 2025

Molecular Design And Engineering Of Luminophores For Aggregation Induced Electrogenerated Chemiluminescence, Jesy Alka Motchaalangaram

Dissertations

Most conventional luminophores produce intense emissions in solutions but suffer from weak emissions or quenching when aggregated in poor solvents due to intermolecular interactions, such as π-π stacking. This phenomenon is known as aggregation caused by quenching (ACQ), limits their applications in their solid state. In contrast, aggregation induced emission (AIE) is a phenomenon in which luminophores are weak- or non-emissive in solution but emit intensively in their aggregated or solid states. AIE has enabled significant advancements in various real-world applications and has inspired new areas of research. The combination of AIE with electrogenerated chemiluminescence (ECL) has resulted in a …


Across The Pond, Across The Waistline: A Comparative Look At The Childhood Obesity Crisis In The United States And United Kingdom, Samantha N. Eales Dec 2025

Across The Pond, Across The Waistline: A Comparative Look At The Childhood Obesity Crisis In The United States And United Kingdom, Samantha N. Eales

Honors College Theses

Childhood obesity is no longer just a local concern; it’s a global epidemic shaping the health of future generations. This paper compares how two similar nations with drastically different healthcare systems, the United States and the United Kingdom, tackle this growing crisis. Although both countries struggle with fast food culture, sedentary lifestyles, and targeted marketing, their health policy strategies differ dramatically. The U.S. leans on community programs and education, while the U.K. enforces stronger national regulations and advertising restrictions. By examining nutrition, physical activity, and policy, this thesis explores what each country does well and where they fall short. It …


A Novel Maturation Equation For Hepatic Clearance Across Preterm, Term Neonates, Children, And Adults: Application To Paracetamol And Its Metabolite, Yunjiao Wu, Swantje Völler, Sebastiaan C. Goulooze, Karel Allegaert, Catherine M.T. Sherwin, Anne Van Rongen, Daniëlla W. E. Roofthooft, Sinno H.P. Simons, Dick Tibboel, Robert B. Flint, John N. Van Den Anker, Catherijne A.J. Knibbe Dec 2025

A Novel Maturation Equation For Hepatic Clearance Across Preterm, Term Neonates, Children, And Adults: Application To Paracetamol And Its Metabolite, Yunjiao Wu, Swantje Völler, Sebastiaan C. Goulooze, Karel Allegaert, Catherine M.T. Sherwin, Anne Van Rongen, Daniëlla W. E. Roofthooft, Sinno H.P. Simons, Dick Tibboel, Robert B. Flint, John N. Van Den Anker, Catherijne A.J. Knibbe

Pediatrics Faculty Publications

A preterm and term neonate to adult (PTNA) maturation equation was introduced recently to describe the glomerular filtration rate maturation from birth to adulthood for neonates of varying gestational age. This study aims to evaluate the newly developed PTNA equation against common maturation approaches like allometric scaling (AS0.75), the AS0.75 plus postmenstrual age (PMA)-based Emax (AS0.75 + PMA) equation, and the bodyweight dependent exponent equation (BDE) for the maturation of three hepatic pathways of paracetamol (PCM) from preterm and term neonates up to adults. A population pharmacokinetic analysis was conducted with pooled plasma and urine data of PCM, PCM-glucuronide (PCM-GLU), …


Assessing Neurocognitive Functioning Among Adults Ageing With And Without Hiv At The Kenyan Coast: Measurement Issues And Correlates, Patrick Nzivo Mwangala, Carophine Nasambu, Ryan Wagner, Mihaela Duta, Gaia Scerif, Charles Newton, Amina Abubakar Dec 2025

Assessing Neurocognitive Functioning Among Adults Ageing With And Without Hiv At The Kenyan Coast: Measurement Issues And Correlates, Patrick Nzivo Mwangala, Carophine Nasambu, Ryan Wagner, Mihaela Duta, Gaia Scerif, Charles Newton, Amina Abubakar

Institute for Human Development, East Africa

Background: Cognitive impairment is one of the most prevalent complications of HIV infection, with significant medical and functional impacts. However, valid, and reliable assessment tools are lacking for the newly emergent ageing population of people living with HIV (PLWH) in many parts of sub-Saharan Africa (SSA), including Kenya. Without these tools, critical intervention opportunities, e.g., psychoeducation, treatment and additional support, are missed. To bridge this gap in Kenya, we adapted the Oxford Cognitive Screen Plus (OCSPlus), a tablet-based cognitive assessment tool designed for low-literacy settings, with adults ageing with HIV ≥ 50 years and their uninfected peers. This study examines …


Understanding Landowner Perceptions: Enhancing Conservation Easement Adoption In Missouri's Priority Landscapes, Mckenna N. Thompson, Jennah I. Klein, Robin M. Rotman, Sonja A. Wilhelm Stanis, Gus C. Raeker, Michele D. Baumer Dec 2025

Understanding Landowner Perceptions: Enhancing Conservation Easement Adoption In Missouri's Priority Landscapes, Mckenna N. Thompson, Jennah I. Klein, Robin M. Rotman, Sonja A. Wilhelm Stanis, Gus C. Raeker, Michele D. Baumer

Faculty Publications

Conservation of private lands is essential for protecting open space, supporting ecosystems and species, preserving resources, and facilitating outdoor recreation. One tool for private land conservation is a conservation easement – a voluntary legal agreement where a landowner surrenders certain rights to use or develop their property. This study explores landowner perceptions of perpetual conservation easements in areas of high conservation value in Missouri, focusing on landowners without existing easements. Through interviews, four themes emerge containing both motivations and constraints: prior knowledge, land protection, regulations, and finance. Many landowners were unfamiliar with conservation easements or had misconceptions or misunderstandings. The …


Behavioral Strategies And Neural Mechanisms Underlying Short-Range Navigation In Teleost Fish, Adelaide Sibeaux, Theresa Burt De Perera, Thomas Mueller, Ronen Segev Dec 2025

Behavioral Strategies And Neural Mechanisms Underlying Short-Range Navigation In Teleost Fish, Adelaide Sibeaux, Theresa Burt De Perera, Thomas Mueller, Ronen Segev

Department of Biology Faculty Scholarship and Creative Works

Studies of spatial cognition in teleosts have uncovered a remarkable array of behavioral strategies and neural mechanisms. While there is compelling evidence that short-range navigation in teleost fish is connected to the telencephalon, the rostral part of the forebrain, little is known about the telencephalic regions mediating this behavior. On the cellular level, several neuron types have been identified in specific regions of the telencephalon that respond to different aspects of the fish’s individual position within a given space. To comprehensively understand spatial representation in fish, we must bridge behavioral and neurophysiological studies. Here, we review the behavioral strategies used …


Maternal-Infant Mortality In West Michigan: A Comparative Literature Review, Mia Cichowlas, Riley Bourlier Dec 2025

Maternal-Infant Mortality In West Michigan: A Comparative Literature Review, Mia Cichowlas, Riley Bourlier

Honors Projects

This literature review aimed to examine and analyze data to identify causes of disparities in infant mortality rates across West Michigan’s four counties, assess demographic factors influencing infant mortality, and explore cultural practices impacting infant outcomes. A comprehensive review of existing literature, public health data, and community health reports from Allegan, Kent, Muskegon, and Ottawa counties was conducted. Key variables examined included race, maternal age, culture, health literacy, education level, income, insurance coverage, employment status, and marital status. Findings indicate that infant mortality rates vary significantly between counties and are higher among certain racial and socioeconomic groups compared to state …


Mi Cuerpo, Mi Salud: A Brief Sexual Health Pilot Intervention For The Promotion Of Latina Sti Testing, Ariana Cervantes-Borges Dec 2025

Mi Cuerpo, Mi Salud: A Brief Sexual Health Pilot Intervention For The Promotion Of Latina Sti Testing, Ariana Cervantes-Borges

Open Access Theses & Dissertations

Disparate rates of sexually transmitted infection (STI) contraction among Latinas and emerging adults highlight glaring public health issues that warrant brief and digital STI testing interventions to promote service acquisition. Latinas may experience a greater negative impact of STIs compared to men, indicating a need to target this population group. Prior studies have noted STI testing intentions and acquisition in Latina populations to be largely impacted by four components: education, stigma, social support, and self-efficacy. Given recent funding cuts for STI research, a brief and digital intervention may circumvent costs associated with traditional intervention implementation. The current study aimed to …


The Mayfly Newsletter, Donna Giberson Dec 2025

The Mayfly Newsletter, Donna Giberson

The Mayfly Newsletter

The Mayfly Newsletter is the official newsletter of the Permanent Committee of the International Conferences on Ephemeroptera.


Neurogenesis And Functional Recovery Of Murine Retinal Ganglion Cells After Glaucoma Induction Following Treatment With Pnu-282987, Samantha Luzadre Dec 2025

Neurogenesis And Functional Recovery Of Murine Retinal Ganglion Cells After Glaucoma Induction Following Treatment With Pnu-282987, Samantha Luzadre

Masters Theses

Experiments were performed to demonstrate electrical recovery in glaucoma-induced adult mice after neurogenesis of retinal ganglion cells (RGCs). Newly derived RGCs were induced following eye drop treatment with a selective alpha7 nicotinic acetylcholine receptor agonist, PNU-282987. Both sexes of transgenic (RlbpCre-ER (CRE+) and Rosa-tdTomato (tdTomato+)) adult mice were utilized to trace newly generated RGCs originating from Müller glia (MG). Experimental mice were injected with hypertonic saline into the episcleral vein of anesthetized mice to significantly increase intraocular pressure (IOP) and induce glaucoma-like conditions. One month after the injection and after significant death of RGCs occurred, mice …


Predicting Cryptocurrency Prices Using Stochastic Modeling, Reem Hani Al Omari Dec 2025

Predicting Cryptocurrency Prices Using Stochastic Modeling, Reem Hani Al Omari

Theses

Cryptocurrencies are digital currencies that operate independently of central banks and governments. They were designed to overcome the limitations of traditional financial systems through a decentralized, peer-to-peer electronic cash mechanism. Trading in cryptocurrencies offers several advantages, including decentralized and efficient transactions, reduced costs through the elimination of intermediaries, investment opportunities across exchanges, and seamless cross-border remittances. Modeling cryptocurrency prices is therefore essential, not only due to these advantages but also because of the substantial market capitalization of cryptocurrencies, estimated to exceed 900 billion dollars according to CoinMarketCap [6]. The main objective of this thesis is to propose a predictive framework …


Effects Of Exercise Or Diet Or Combined Interventions On Treatment Efficacy Of Chemotherapy For Cancer: A Systematic Review, Cristina Crespo-Garcia, Francesco Bettariga, Dennis R. Taaffe, Carolyn J. Peddle-Mcintyre, John P. Campbell, Emily Jeffery, Anna Maria Markarian, Anita Borsati, Alice Avancini, Sara Pilotto, Daniel A. Galvao, Robert U. Newton Dec 2025

Effects Of Exercise Or Diet Or Combined Interventions On Treatment Efficacy Of Chemotherapy For Cancer: A Systematic Review, Cristina Crespo-Garcia, Francesco Bettariga, Dennis R. Taaffe, Carolyn J. Peddle-Mcintyre, John P. Campbell, Emily Jeffery, Anna Maria Markarian, Anita Borsati, Alice Avancini, Sara Pilotto, Daniel A. Galvao, Robert U. Newton

Research outputs 2022 to 2026

Purpose of Review: While exercise and dietary interventions in patients with cancer undergoing chemotherapy have been demonstrated to be safe and feasible and improve patient-reported outcomes, the effects on treatment efficacy have not been widely examined and remain unclear. This review aimed to examine the effects of exercise, dietary, and combined interventions on tumour response and time-to-event outcomes in patients with cancer undergoing chemotherapy. Recent Findings: A systematic review of intervention studies was conducted based on PRISMA guidelines Databases searched were PubMed, Medline, CINAHL, Embase, and Web of Science. Methodological quality and risk of bias were assessed using the RoB2 …


Impacts Of Dredging And Restoration On Sedimentary Carbon Stocks In Seagrass Meadows Of Pari Island, Indonesia, Yusmiana P. Rahayu, Gary A. Kendrick, Pere Masqué, Wawan Kiswara, Hadiwijaya L. Salim, Ali A. Lubis, Mathew A. Vanderklift Dec 2025

Impacts Of Dredging And Restoration On Sedimentary Carbon Stocks In Seagrass Meadows Of Pari Island, Indonesia, Yusmiana P. Rahayu, Gary A. Kendrick, Pere Masqué, Wawan Kiswara, Hadiwijaya L. Salim, Ali A. Lubis, Mathew A. Vanderklift

Research outputs 2022 to 2026

The effects of dredging and restoration on carbon sequestration in seagrass sediments is not well understood. Our knowledge is derived from few studies conducted in areas affected by dredging or restoration, the majority of which are from temperate regions. There is limited information available for tropical regions, where seagrass sediments can differ greatly in species composition, geomorphology, and hydrodynamic conditions. This study aims to assess the effects of dredging and seagrass restoration on sediment organic carbon concentrations and stocks at Pari Island, Indonesia. The results indicated that sediment organic carbon concentrations (%Corg) were higher in persistent seagrass meadows than in …


Interpretive Prediction Of Hyperuricemia And Gout Patients Via Machine Learning Analysis Of Human Gut Microbiome, Jia Wei Tang, Alfred Chin Yen Tay, Liang Wang Dec 2025

Interpretive Prediction Of Hyperuricemia And Gout Patients Via Machine Learning Analysis Of Human Gut Microbiome, Jia Wei Tang, Alfred Chin Yen Tay, Liang Wang

Research outputs 2022 to 2026

Hyperuricemia (HUA) and gout result from imbalances in uric acid metabolism and are closely associated with the gut microbiota. Advanced analytical methods facilitate the exploration of microbiota complexity. In this study, 16S rRNA sequencing data from stool samples of 233 patients were thoroughly collected. Machine learning (ML) and Shapley Additive exPlanations (SHAP) interpretability algorithms were applied to identify core taxa and predict the metabolic functions. The results revealed that the high-contribution core taxa identified by SHAP in each group, such as Oscillospiraceae_UCG-005 and Rhodococcus provided the basis for ML prediction. Among the five classification models, Random Forest (RF) achieved the …


Sediment Burial Negatively Impacts The Growth Of Seagrass Posidonia Sinuosa, Chanelle Webster, Nicole Said, Natasha Dunham, Simone Strydom, Kathryn Mcmahon Dec 2025

Sediment Burial Negatively Impacts The Growth Of Seagrass Posidonia Sinuosa, Chanelle Webster, Nicole Said, Natasha Dunham, Simone Strydom, Kathryn Mcmahon

Research outputs 2022 to 2026

Burial disturbances affect foundation plant species in marine ecosystems. Deposition of dredge spoil can bury seagrass meadows yet we have limited threshold information to predict the trajectory of impact from burial or possible recovery. To investigate the response to burial by dredge spoil, established seagrass ramets of Posidonia sinuosa were collected from a population in Western Australia and exposed to cutter suction dredge spoil sediment. Plant responses were measured during a burial phase after 2, 4 and 8 weeks to assess the influence of duration to burial depths (0, 1, 4, 8 and 16 cm). Sediments were then removed, and …


Soil Organic Carbon Depth Profiles And Centennial And Millennial Decay Rates In Tidal Marsh, Mangrove And Seagrass Blue Carbon Ecosystems, Nerea Piñeiro-Juncal, Miguel Ángel Mateo, Carmen Leiva-Dueñas, Eduard Serrano, Karina Inostroza, Montserrat Soler, Eugenia T. Apostolaki, Paul Lavery, Carlos M. Duarte, Anna Lafratta, Oscar Serrano Dec 2025

Soil Organic Carbon Depth Profiles And Centennial And Millennial Decay Rates In Tidal Marsh, Mangrove And Seagrass Blue Carbon Ecosystems, Nerea Piñeiro-Juncal, Miguel Ángel Mateo, Carmen Leiva-Dueñas, Eduard Serrano, Karina Inostroza, Montserrat Soler, Eugenia T. Apostolaki, Paul Lavery, Carlos M. Duarte, Anna Lafratta, Oscar Serrano

Research outputs 2022 to 2026

The management of coastal blue carbon ecosystems can contribute to mitigate anthropogenic greenhouse gas emissions. However, limited information on soil organic carbon (OC) decay rates in tidal marsh, mangrove, and seagrass soils hinders their inclusion in climate strategies and carbon-crediting schemes. Here, we analyzed downcore OC trends in 3761 soil cores from blue carbon ecosystems worldwide. A decrease in OC content with soil depth was measured in 63% of the cores, whereas stable and increasing trends were observed in 22% and 15% of the cores, respectively. Based on 85 profiles where OC decay could be modelled, the OC decay rate …


Exploring Fathers’ Child And Family Support During Aboriginal Mothers’ Incarceration, Bon Miu, Paul Leslie Simpson, Tony Butler, Mandy Wilson, Destiny Kynuna, Robert Shaw, Jocelyn Jones Dec 2025

Exploring Fathers’ Child And Family Support During Aboriginal Mothers’ Incarceration, Bon Miu, Paul Leslie Simpson, Tony Butler, Mandy Wilson, Destiny Kynuna, Robert Shaw, Jocelyn Jones

Research outputs 2022 to 2026

Aboriginal women are one of the fastest-growing subgroups among the Australian incarcerated population. Their incarceration affects increasing numbers of children, families, and communities. Few studies have examined the role of fathers when mothers are incarcerated. Using 49 in-depth interviews with Aboriginal mothers in Western Australian prisons, we explore the types of child and family support fathers provide based on the incarcerated mother’s perspective. Four themes were identified: (1) diverse support and involvement by fathers; (2) absence of father’s support due to death or incarceration; (3) parental cooperation and communication; and (4) supports and challenges to maintaining family networks. Overall, fathers …


Pact Is Requisite For Prostate Cancer Cell Proliferation, Dianne J. Beveridge, Andrew J. Woo, Kirsty L. Richardson, Rikki A.M. Brown, Lisa M. Stuart, Manjot Singh, Andrew D. Redfern, Peter J. Leedman Dec 2025

Pact Is Requisite For Prostate Cancer Cell Proliferation, Dianne J. Beveridge, Andrew J. Woo, Kirsty L. Richardson, Rikki A.M. Brown, Lisa M. Stuart, Manjot Singh, Andrew D. Redfern, Peter J. Leedman

Research outputs 2022 to 2026

PACT (encoded by the PRKRA gene) is a double-stranded RNA binding protein with defined antiviral defense and cytoplasmic RNA-induced silencing actions in mammals. We previously described a further role for PACT as a modulator of nuclear receptor (NR)-regulated gene expression. Here, we investigated the role of PACT in prostate cancer (PCa) using a loss-of-function approach. Depletion of PACT in multiple PCa cell lines resulted in a reduction in cell proliferation, but viability was maintained. RNA-sequencing analysis of LNCaP PCa cells ± PACT revealed a depletion of biological processes involved in cell cycle, mitochondrial function, and NR-response pathways in the PACT …


Global Estimates Of Seagrass Blue Carbon Stocks In Biomass And Net Primary Production, Enric Gomis, Simone Strydom, Nicole R. Foster, Diana Montemayor, Miguel A. Mateo, Eduard Serrano, Karina Inostroza, Roisin Mccallum, Anna Lafratta, Chanelle L. Webster, Caitlyn L. O’Dea, Nicole E. Said, Natasha Dunham, Rachele Bernasconi, Axel Werner, Federico Vitelli, Viena Puigcorbé, Alexandra D’Cruz, Cristian Salinas, Kathryn M. Mcmahon, Glenn A. Hyndes, Paul S. Lavery, Albert Pessarodona, Carlose M. Duarte, Oscar Serrano Dec 2025

Global Estimates Of Seagrass Blue Carbon Stocks In Biomass And Net Primary Production, Enric Gomis, Simone Strydom, Nicole R. Foster, Diana Montemayor, Miguel A. Mateo, Eduard Serrano, Karina Inostroza, Roisin Mccallum, Anna Lafratta, Chanelle L. Webster, Caitlyn L. O’Dea, Nicole E. Said, Natasha Dunham, Rachele Bernasconi, Axel Werner, Federico Vitelli, Viena Puigcorbé, Alexandra D’Cruz, Cristian Salinas, Kathryn M. Mcmahon, Glenn A. Hyndes, Paul S. Lavery, Albert Pessarodona, Carlose M. Duarte, Oscar Serrano

Research outputs 2022 to 2026

Seagrass meadows play a key role in the global carbon cycle through storing carbon in their biomass and soils. However, the lack of global assessments of carbon stocks in seagrass biomass and net primary production (NPP) limits our understanding of their role in the carbon cycle. Here, we provide global estimates of biomass carbon stocks and NPP encompassing seagrasses with different life-history strategies, across bioregions and 66 countries. Seagrass meadows show up to 800-fold differences in biomass across different life-history strategies and bioregions (mean ± SE; 1551 ± 40 kg C ha−1), whereas seagrass NPP (5833 ± 557 …


Sertraline To Reduce Recidivism In Impulsive Violent Offenders (Reinvest): A Randomised Double Blind Clinical Trial, Tony Butler, Emaediong I. Akpanekpo, Lee Knight, Kristy Robledo, David Greenberg, Andrew Ellis, Stephen Allnutt, Kay Wilhelm, Alison Jones, Rodney Scott, Bianca Ton, Luke Grant, Philip Mitchell, Ross Tynan, Jocelyn Jones, Dominic Villa, Duncan Chappell, Carolynn Dixon, Alison Churchill, Val Gebski, Tony Keech, Peter W. Schofield Dec 2025

Sertraline To Reduce Recidivism In Impulsive Violent Offenders (Reinvest): A Randomised Double Blind Clinical Trial, Tony Butler, Emaediong I. Akpanekpo, Lee Knight, Kristy Robledo, David Greenberg, Andrew Ellis, Stephen Allnutt, Kay Wilhelm, Alison Jones, Rodney Scott, Bianca Ton, Luke Grant, Philip Mitchell, Ross Tynan, Jocelyn Jones, Dominic Villa, Duncan Chappell, Carolynn Dixon, Alison Churchill, Val Gebski, Tony Keech, Peter W. Schofield

Research outputs 2022 to 2026

Background: Biological studies suggest serotonin modulation via selective serotonin reuptake inhibitors (SSRIs) might reduce impulsive violence, however, robust evidence in offender populations is limited. We aimed to determine whether sertraline reduces violent reoffending compared with placebo in highly impulsive men with recurrent violent offending.

Methods: We conducted a double-blind, placebo-controlled, randomised clinical trial in community settings in New South Wales, Australia. Eligible participants were men aged 18 years or older with ≥2 prior violent convictions and a Barratt Impulsiveness Scale score ≥70. Following a 4-week single-blind active run-in phase with sertraline, participants were randomly assigned (1:1, minimization stratified by key …


Alzheimer’S Disease Biological Pet Staging Using Plasma P217+Tau, Azadeh Feizpour, Vincent Doré, Natasha Krishnadas, Pierrick Bourgeat, James D. Doecke, Ziad S. Saad, Gallen Triana-Baltzer, Simon M. Laws, Rosita Shishegar, Kun Huang, Christopher Fowler, Larry Ward, Colin Masters, Jurgen Fripp, Hartmuth Kolb, Victor Villemagne, Christopher Rowe Dec 2025

Alzheimer’S Disease Biological Pet Staging Using Plasma P217+Tau, Azadeh Feizpour, Vincent Doré, Natasha Krishnadas, Pierrick Bourgeat, James D. Doecke, Ziad S. Saad, Gallen Triana-Baltzer, Simon M. Laws, Rosita Shishegar, Kun Huang, Christopher Fowler, Larry Ward, Colin Masters, Jurgen Fripp, Hartmuth Kolb, Victor Villemagne, Christopher Rowe

Research outputs 2022 to 2026

Background: Plasma phospho-tau biomarkers, such as p217+tau, excel at identifying Alzheimer’s disease (AD) neuropathology. However, their ability to substitute for tau PET to identify AD biological stage is unclear. Methods: Participants included 248 cognitively unimpaired (CU) and 227 cognitively impaired (CI) individuals, with Janssen plasma p217+tau Simoa® assay, 18F-NAV4694 Aβ-PET (A) and 18F-MK6240 tau-PET (T) data. Biological PET stages were defined according to the Revised Criteria for Diagnosis and Staging of Alzheimer’s Disease (2024): Initial (A + T-), Early (A + TMTL +), Intermediate (A + TMOD +), and Advanced (A + THIGH +). The threshold for A+ was 25 …


Language Learner Literature: A Mixed Methods Study, Esmeralda Mora Dec 2025

Language Learner Literature: A Mixed Methods Study, Esmeralda Mora

Dissertations

This dissertation, Language Learner Literature: A Mixed Methods Study, by Esmeralda Mora, Ed.D., of National Louis University, specializing in Curriculum, Advocacy, and Policy, investigated the impact of shifting a Midwest high school world language department from a traditional, grammar-focused model to a proficiency-based approach centered on Language Learner Literature (LLL). Employing a Modified Explanatory Sequential Mixed Methods Design, the study first analyzed longitudinal AAPPL proficiency scores from 1,134 high school students (2020–2025) using T-tests and Multiple Linear Regressions to establish measurable outcomes (the "what"). This quantitative phase demonstrated significant and consistent gains in expressive skills (Writing and Speaking) post-LLL implementation, …


Bone Void Filler Materials For Augmentation In Comminuted Fractures: A Comprehensive Review, S. Sina Mohammadi, Sunjeev S. Phull, B. Sonny Bal, Mark R. Towler Dec 2025

Bone Void Filler Materials For Augmentation In Comminuted Fractures: A Comprehensive Review, S. Sina Mohammadi, Sunjeev S. Phull, B. Sonny Bal, Mark R. Towler

Chemical and Biochemical Engineering Faculty Research & Creative Works

Comminuted fractures, characterized by multiple bone fragments, present significant challenges in orthopedic surgery. Effective treatment often requires augmentation techniques to enhance fixation stability and promote bone regeneration. This review explores the application of bone void filler materials, including autografts, allografts, polymethyl methacrylate (PMMA), and synthetic bone substitutes such as calcium phosphate ceramics and bioactive glass, in managing comminuted fractures. Autografts are the gold standard due to their superior osteogenic potential but are limited by donor site morbidity and availability. Allografts mitigate these issues but face concerns regarding immunogenicity and reduced biological activity. PMMA, widely used for structural augmentation, provides immediate …


Salinity Adaption And Toxicity Of Harmful Algal Blooms In Three Bays Of Great Salt Lake (Usa), W. A. Wurtsbaugh, Malin Olofsson, Gregory L. Boyer, Amy Marcarelli Dec 2025

Salinity Adaption And Toxicity Of Harmful Algal Blooms In Three Bays Of Great Salt Lake (Usa), W. A. Wurtsbaugh, Malin Olofsson, Gregory L. Boyer, Amy Marcarelli

Michigan Tech Publications

Cyanobacterial blooms can be harmful to animals and humans exposed to their toxins; however, their environmental drivers and boundaries still need to be elucidated. Salinity has been demonstrated to be an important driver of community composition that sets boundaries of species migration and survival. The filamentous cyanobacteria Nodularia spumigena forms dense blooms in estuaries around the world, produces the hepatotoxin nodularin, and has been thought to not survive or fix nitrogen (N) in high salinities. From 2005–2009 we studied three bays of Great Salt Lake (USA), two of which are estuaries with salinities ranging from 0 to >90 g L …


Integration Of Oral Health Assessment In Medicare Visits: A Survey Of Primary Care Physicians In Montana And Their Role In Patients Aged 65+, Cheyenne R. Smith Dec 2025

Integration Of Oral Health Assessment In Medicare Visits: A Survey Of Primary Care Physicians In Montana And Their Role In Patients Aged 65+, Cheyenne R. Smith

Dental Hygiene ETDs

The integration of oral health assessments into primary care settings has been strongly advocated to enhance access to care for elderly individuals. Medical and dental professionals recognize the critical connection between oral health and systemic health. Physicians can play a key role in enhancing oral health care by incorporating an oral health assessment into routine general health appointments, such as the Medicare Annual Wellness Visit (AWV). Physicians in Montana were invited to participate in an anonymous study to gather their opinions on conducting oral health assessments in primary care settings, identify barriers to providing these assessments, and evaluate their knowledge …


Diagnostic Accuracy Of Nanopore Sequencing For Detecting Mycobacterium Tuberculosis And Drug-Resistant Strains: A Systematic Review And Meta-Analysis, Timothy Hudson David Culasino Carandang, Dianne Jaula Cunanan, Gail S. Co, John David Pilapil, Juan Ignacio Garcia, Blanca I. Restrepo, Marcel Yotebieng, Jordi B. Torrelles, Kin Israel Notarte Dec 2025

Diagnostic Accuracy Of Nanopore Sequencing For Detecting Mycobacterium Tuberculosis And Drug-Resistant Strains: A Systematic Review And Meta-Analysis, Timothy Hudson David Culasino Carandang, Dianne Jaula Cunanan, Gail S. Co, John David Pilapil, Juan Ignacio Garcia, Blanca I. Restrepo, Marcel Yotebieng, Jordi B. Torrelles, Kin Israel Notarte

Ateneo School of Medicine and Public Health Publications

Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB) infection, remains a significant public health threat. The timeliness, portability, and capacity of nanopore sequencing for diagnostics can aid in early detection and drug susceptibility testing (DST), which is crucial for effective TB control. This study synthesized current evidence on the diagnostic accuracy of the nanopore sequencing technology in detecting MTB and its DST profile. A comprehensive literature search in PubMed, Scopus, MEDLINE, Cochrane, EMBASE, Web of Science, AIM, IMEMR, IMSEAR, LILACS, WPRO, HERDIN Plus, MedRxiv, and BioRxiv was performed. Quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. Pooled …


Twim #261: Overwhelming Microbial Greatness, Jenny Stoval, Briana Lanzarotta, Luke Boseman, Nicole L. Podnecky, Angela Wilson Dec 2025

Twim #261: Overwhelming Microbial Greatness, Jenny Stoval, Briana Lanzarotta, Luke Boseman, Nicole L. Podnecky, Angela Wilson

School of Medical Diagnostics & Translational Sciences Publications

Podcast annotation TWiM #261: Overwhelming Microbial Greatness from the weekly podcast series "This Week in Microbiology" (TWiM), a podcast where experts in microbiology discuss academic papers in their field in an informal way.