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The War On Drugs: An Analysis Of The Rhetoric According To Richard Weaver’S Theory Of Ultimate Terms, Cristina Peniche

Masters Theses

The language associated with President Nixon’s ‘war on drugs’ has sparked considerable debate in the political struggle against narcotics' abuse and crime, as well as within scholarly research. There is a language associated with the debate and it reflects the primary considerations of policy makers- economics, criminal behavior, and morality. The present study discusses these qualities as well as the rhetorical ideas of Richard Weaver, specifically his theory of ultimate terms. Then, discussions within research show the discontent that scholars bear towards narcotics'-related language. Specifically, there is concern that the rhetoric may stigmatize certain populations and hinder better outcomes. As …

Characterising Cytotoxicity And Genotoxicity Of Chemotherapeutic Agents (Etoposide And Vincristine) On Tk6, A Human Lymphoblastoid Cell Line, Leanne Edermaniger

The Plymouth Student Scientist

The ability of the chemotherapeutic agents namely etoposide and vincristine to cause cytotoxic and genotoxic damage to the human lymphoblastoid cell line, TK6, was at the centre of this study. Four different cytotoxic assays were tested for their ability to assess the cytotoxicity of the agents as well as two genotoxic assays to examine their ability to induce DNA damage. The TK6 cell line was exposed to increasing doses of the chemotherapeutic agents and cytoxicity assessed by in vitro trypan blue, neutral red uptake, LDH leakage and the glucose oxidase assays. The trypan blue assay was deemed to be the …

Effects Of Storm-Induced Sand Scour On Patella Vulgata Off South-West Britain, Jake Jefford

The Plymouth Student Scientist

This study investigates the impacts of storm-induced sand-scour on common limpets (Patella vulgata) off south-west Britain, focussing particularly on the physical impacts of this process, as well as shore recovery. Unusually polished limpets were found living on a rocky shore (Westcombe Beach, South Devon) following a series of large storms that occurred from December 2013 to mid-February 2014. The extent of the storms was completely unprecedented, and it was one of the most exceptional periods of winter rainfall in Englandin at least 248 years when records began. It was clear that the limpets and surrounding epilithic communities at Westcombe Beach …

Exposure To Predator Kairomones Influences Egg Number And Size In Littorina Littorea, Jessica Raynor, Simon Rundle

The Plymouth Student Scientist

Predator kairomones play an important role in intertidal ecosystems, but knowledge on their potential role in influencing maternal effects is lacking. The aim of this study was to test whether egg production by female Littorina littorea was influenced by short-term exposure to predator kairomones before egg laying. Laboratory populations were exposed to predator cues from the intertidal crab Carcinus maenas for nine days, and egg number, egg size, and survivorship of the offspring were measured and compared with those from reference populations. Snails exposed to predator cues produced significantly more eggs, which were also significantly smaller than those produced from …

Plymouth Undergraduate Research In Mathematics, Tom Heinzl, Tom Mccourt

The Plymouth Student Scientist

Guest editorial from lectures in Physics and Pure Mathematics.

Energy Harvesting In A Diver's Rebreather System, Joseph Ely

The Plymouth Student Scientist

This report investigates the feasibility of energy harvesting using thermoelectric generators in a diver’s rebreather system. The report details research into documented experiments and theory, design and manufacture of an energy harvesting prototype and testing of the prototype to determine its feasibility. The prototype produced a maximum power of 2.5 (mW) which is more than the minimum 50 microwatts of power specified by Avon. It was therefore concluded that energy harvesting within a divers rebreather system is feasibility.

The Efficacy Of Levodopa+Ddc Inhibitor+Entacapone Versus Levodopa+Ddc Inhibitor+Placebo In Parkinson's Disease: An Intervention Review, Jennifer Harrison

The Plymouth Student Scientist

Parkinson's disease (PD) has many possible treatment options. The main therapy uses a drug called levodopa. However after prolonged use, this drug begins to wear off and becomes less effective. Therefore additional drugs are needed to help ensure the patient is comfortable and to aid the relief of symptoms that can often occur. The addition of the COMT inhibitor, entacapone, aims to reduce motor symptoms and smooth out fluctuations that can sometimes be experienced with levodopa therapy. These can include bradykinesia, which is slowness of movement and help to control the resting tremor that is often associated with PD. The …

You Can't Tickle Yourself...Or Can You? The Effect Of A Hypnotic Suggestion On Sensory Attenuation Phenomenon, Shamsideen Yusuf

The Plymouth Student Scientist

The internal motor simulation mechanism is widely believed to generate anticipatory sensory outcomes on the basis of the efferent copy of the motor commands. What is currently unknown is whether the motor prediction mechanism can integrate non-motor inputs such as a hypnotic suggestion in generating sensory predictions. Seventy-two undergraduate students (M=12, F=60) were recruited via Plymouth University participation pool, to undergo a randomised hypnotic suggestion (IV) of either an alien- hand or an alien-foot. The participants were asked to apply tactile stimulation to their left palm (DV) before and after the suggestion and report the tickling sensations. The results revealed …

Bimetallic-Waveguide Coupled Sensors For Tunable Plasmonic Devices, Kunal K. Tiwari

Physics Dissertations - Archive

Surface plasmon resonance (SPR) has been a widely used optical technique for the real time and label free sensing applications in biomedicine, homeland security, food safety, environmental monitoring, etc. Surface plasmons (SPs) being extremely sensitive to the surrounding media, their characteristics can be modulated by tuning their dielectric environment. The unique property of the nematic liquid crystalline materials that their dielectric constant can be tuned by externally applied electric fields formed the basis for development of tunable plasmonic sensor for monitoring changes at metal/dielectric interfaces. Even though sensors with high sensitivity are available, it remains highly desirable to enhance sensor …

Genetic Dissection Of Disease Resistance To The Blue Mold Pathogen, Peronospora Tabacina, In Tobacco, Xia Wu, Dandan Li, Yinguang Bao, David Zaitlin, Robert D. Miller, Shengming Yang

Plant and Soil Sciences Faculty Publications

Tobacco blue mold, caused by the obligately biotrophic oomycete pathogen Peronospora tabacina D.B. Adam, is a major foliar disease that results in significant losses in tobacco-growing areas. Natural resistance to P. tabacina has not been identified in any variety of common tobacco. Complete resistance, conferred by RBM1, was found in N. debneyi and was transferred into cultivated tobacco by crossing. In the present study, we characterized the RBM1-mediated resistance to blue mold in tobacco and show that the hypersensitive response (HR) plays an important role in the host defense reactions. Genetic mapping indicated that the disease resistance …

Data In Support Of Ubsrd: The Ubiquitin Structural Relational Database, Joseph S. Harrison, Tim M. Jacobs, Kevin Houlihan, Koenraad Van Doorslaer, Brian Kuhlman

College of the Pacific Faculty Articles

This article provides information to support the database article titled "UbSRD: The Ubiquitin Structural Relational Database" (Harrison et al., 2015) [1] . The ubiquitin-like homology fold (UBL) represents a large family that encompasses both post-translational modifications, like ubiquitin (UBQ) and SUMO, and functional domains on many biologically important proteins like Parkin, UHRF1 (ubiquitin-like with PDB and RING finger domains-1), and Usp7 (ubiquitin-specific protease-7) (Zhang et al., 2015; Rothbart et al., 2013; Burroughs et al., 2012; Wauer et al., 2015) [2], [3], [4], [5]. The UBL domain can participate in several unique protein-protein interactions (PPI) since protein adducts can be attached …

Nanoparticle Conversion To Biofilms: In Vitro Demonstration Using Serum-Derived Mineralo-Organic Nanoparticles, Tsui-Yin Wong, Hsin-Hsin Peng, Cheng-Yeu Wu, Jan Martel, David M. Ojcius, Fu-Yung Hsu, John Ding-E. Young

All Dugoni School of Dentistry Faculty Articles

Aims: Mineralo-organic nanoparticles (NPs) detected in biological fluids have been described as precursors of physiological and pathological calcifications in the body. Our main objective was to examine the early stages of mineral NP formation in body fluids. Materials & methods: A nanomaterial approach based on atomic force microscopy, dynamic light scattering, electron microscopy and spectroscopy was used. Results: The mineral particles, which contain the serum proteins albumin and fetuin-A, initially precipitate in the form of round amorphous NPs that gradually grow in size, aggregate and coalesce to form crystalline mineral films similar to the structures observed in calcified human arteries. …

Crystallographic Education In The 21st Century, Saulius Gražulis, Amy Alexis Sarjeant, Peter Moeck, Jennifer Stone-Sundberg, Trevor J. Snyder, Werner Kaminsky, Allen G. Oliver, Charlotte L. Stern, Louise N. Dawe, Denis A. Rychkov, Evgeniy A. Losev, Elena V. Boldyreva,, Joseph M. Tanski, Joel Bernstein, Wael M. Rabeh, Katherine A. Kantardjieff

Physics Faculty Publications and Presentations

There are many methods that can be used to incorporate concepts of crystallography into the learning experiences of students, whether they are in elementary school, at university or part of the public at large. It is not always critical that those who teach crystallography have immediate access to diffraction equipment to be able to introduce the concepts of symmetry, packing or molecular structure in an age- and audience-appropriate manner. Crystallography can be used as a tool for teaching general chemistry concepts as well as general research techniques without ever having a student determine a crystal structure. Thus, methods for younger …

Proposal And Report For Grant 109: Introduction To Environmental Science, Samuel Mutiti, Caralyn Zehnder, Kalina Manoylov, Christine Mutiti

ALG Legacy Reports

This proposal and final report are from the first ALG grants finishing between Spring 2015 and Spring 2016. They have been republished in the repository in order to move our first reports over from being hosted on the ALG website.

Patients' Perception Of The Use Of Motivational Interviewing For Childhood Obesity Treatment: A Qualitative Study, Penelope L. Neal Dr.

Electronic Theses and Dissertations

The purpose of this qualitative interpretive descriptive study was to better understand children’s perceptions of the use of motivational interviewing (MI) as a communication style for childhood obesity treatment. Childhood obesity in the United States has reached epidemic proportions and much research effort has been dedicated to reversing this trend. One approach that has demonstrated positive outcomes in the clinical setting is MI. Leading organizations in pediatric healthcare now recommend MI as a communication style to be used for childhood obesity-related behavior change. Although empiric studies have demonstrated improvement in outcomes when this communication style is used with patients and …

Teaching The Spiritual Dimension Of Nursing Care: A Survey Of Associate Degree Nursing Programs In The Southeast United States, Nancy L. Labine

Electronic Theses and Dissertations

Spirituality is a subject which is often neglected in nursing education. The purpose of this study was to determine associate degree nursing faculty’s perception of their ability to teach the spiritual dimension in the delivery of nursing care. The study explored whether faculty have received training related to spiritual care, how and where nursing programs integrate spirituality education into the curriculum, nursing faculty’s understanding of the terms spirituality and spiritual care, and faculty members perception of whether they receive sufficient support and guidance in teaching related to spirituality and spiritual care.

Survey research was used in this study. The participants …

Sophorolipid Production From Lignocellulosic Biomass Feedstocks, Abdul Samad

Theses

The present study investigated the feasibility of production of sophorolipids (SLs) using yeast Candida bombicola grown on hydrolysates derived lignocellulosic feedstock either with or without supplementing oil as extra carbon source. Several researchers have reported using pure sugars and various oil sources for producing SLs which makes them expensive for scale-up and commercial production. In order to make the production process truly sustainable and renewable, we used feedstocks such as sweet sorghum bagasse, corn fiber and corn stover. Without oil supplementation, the cell densities at the end of day-8 was recorded as 9.2, 9.8 and 10.8 g/L for hydrolysate derived …

Uncovering Potential Causes Of Resistance Of Soybean To Scn, Oleksandra Zatserklyana

Theses

It is widely known that Glycine max L. Merr., commonly known as soybean is one of the major agricultural crops in the United States and is an agricultural crop in other countries as well. Yet, the yearly yield of soybean is not as high as can be expected due to Heterodera glycines Ichinole, or soybean cyst nematode (later, SCN). SCN is one of the most destructive pests and pathogens of soybean and the main methods for control have proven to be problematic and time-consuming so far (Koenning 2000; UIPC 2015). Lineages of soybean that are resistant to SCN have been …

Protective Effect Of Gymnema Sylvestre L. Against Advanced Glycation End-Product, Sorbitol Accumulation And Aldose Reductase Activity In Homoeopathic Formulation, Lalit Kishore, Randhir Singh

Indian Journal of Research in Homoeopathy

Background: Oxidative stress ensues due to the imbalance between the production and elimination of reactive oxygen species. Chronic hyperglycemia along with oxidative stress plays major role in aggravation of chronic disorders such as diabetes and its related complications. Objective: This study was designed to evaluate the protective effect of Gymnema sylvestre L. against oxidative stress. Materials and Methods: Potencies of G. Sylvestre were procured from Dr. Willmar Schwabe India Pvt. Ltd. In vitro antioxidative potential of G. sylvestre was evaluated by employing various in vitro antioxidant methods. Results: The total phenol content was found to be 2124, 998 and 546 …

Virtual Screening Of Phytochemicals For Cancer Therapy, Asma Ahmad Al Haddad

Theses

Cancer is one of the leading cause of deaths in the world. Vast majority of contemporary cancer therapies have side effects. Dietary plants and plant-based products have been shown to reduce the severity of the condition with minimal or no side effects. However, the precise molecular interactions that lead to this are largely unknown. In this study, several target proteins in cancer pathways were chosen and a collection of chemical derived from plants, or phytochemicals, were virtually screened in silico using molecular docking techniques. Furthermore, the docking modes were subjected to extended molecular dynamics (MD) simulations. The pharmacokinetic properties of …

Mountain Big Sagebrush (Artemisia Tridentata Ssp Vaseyana) Seed Production, Melissa L. Landeen

Theses and Dissertations

Big sagebrush (Artemisia tridentata Nutt.) is the most widespread and common shrub in the sagebrush biome of western North America. Of the three most common subspecies of big sagebrush (Artemisia tridentata), mountain big sagebrush (ssp. vaseyana; MBS) is the most resilient to disturbance, but still requires favorable climactic conditions and a viable post-fire seedbank for successful unassisted recovery. This study was designed to assess MBS seed production throughout post-fire recovery. We performed 2 pilot studies to develop methods for estimating seed production and plant age. The results of the pilot studies and a space-for-time substitution strategy were used to measure …

Advanced Data Analysis Tools And Multi-Instrument Material Characterization, Bhupinder Singh

Theses and Dissertations

My dissertation focuses on (i) the development of new analysis tools and methodologies for analyzing X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (ToF-SIMS) data, and (ii) the comprehensive characterization of materials (nanodiamonds) using a multi-instrument approach. Chapter 1 contains (i) a discussion of the two techniques I focused on most in my work: XPS and ToF-SIMS, (ii) a discussion of the common chemometrics techniques used to analyze data from these methods, and (iii) the advantages/rationale behind the multi-instrument characterization of materials. Chapter 2 describes various good practices for obtaining reasonable peak fits in XPS, which can also …

Gene Networks Involved In Competitive Root Colonization And Nodulation In The Sinorhizobium Meliloti-Medicago Truncatula Symbiosis, Ryan D. Vanyperen

Theses and Dissertations

The rhizobia-legume symbiosis is the most agriculturally significant source of naturally fixed nitrogen, accounting for almost 25% of all biologically available nitrogen. Rhizobia-legume compatibility restrictions impose limits on symbiotic nitrogen fixation. In many cases, the molecular basis for symbiotic compatibility is not fully understood. The signals required for establishing a symbiotic partnership between nitrogen-fixing bacteria (e.g. Sinorhizobium meliloti) and leguminous plants (e.g. Medicago truncatula) have been partially characterized at the molecular level. The first stage of successful root colonization is competitive occupation of the rhizosphere (which is poorly understood). Here, the bacteria introduce themselves as potential symbiotic partners …

New Orleans Opera Association: An Internship Report, Sarah Mccall

Arts Administration Master's Reports (1984-2016)

As one of the requirements to complete a Master of Arts in Arts Administration, this internship report presents a thorough discussion and analysis of my experience as an intern with the New Orleans Opera Association between May 2015 and August 2015. The focus of the internship was production, and the report reflects this emphasis. In addition, the report presents an overview of the organization, a SWOT analysis, and a discussion of best practices with recommendations for the organization’s improvement.

Electrochemical Formation Of One-Dimensional Metal Nanostructures Across Microgaps Electrodes For Resistive Switching And Optical Sensing Applications., Nidhi Shah

Electronic Theses and Dissertations

This dissertation focuses on the electrochemical formation of one-dimensional (1D) Ag nanostructures (in particular nanowires and nanochains) directly on electrode surfaces or gap of two electrodes. Ag nanowires (NWs) and nanorods (NRs) grow directly on glass/indium tin oxide (ITO) surfaces from electrode-attached Au nanoparticle seeds in the presence of cetyltrimethylammonium bromide (CTAB) at appropriate potentials with a 5-15 % yield and the average length ranging from 100 nm to 3 µm for growth times of 30 to 120 min. This method failed when trying to grow Ag NRs/NWs across 5 µm Au electrode gaps. Interestingly, applying voltage in air leads …

Effects Of Resistance Training And Creatine Monohydrate On Doxorubicin-Induced Muscle Dysfunction, Eric Christopher Bredahl

Dissertations

Doxorubicin (DOX) is a powerful chemotherapy agent that is associated with a number of deleterious side effects, including skeletal muscle dysfunction. The exact mechanisms behind the observed skeletal muscle dysfunction have yet to be fully understood. Nonetheless, the observed myotoxicity is believed to be the result of an increased oxidative stress. Resistance training (RT) has been shown to preserve skeletal muscle function in DOX treated muscles. Conversely, creatine (Cr) has been shown to improve skeletal muscle function. Yet, there has been no investigation into the effect of combined RT and Cr on DOX-induced muscle dysfunction. Thus, the possibility exists that …

Exploring Male Counselors’ Experiences With Vulnerability In The Counseling Relationship, Hannah Edith Davis Kreider

Dissertations

While existing literature clearly indicates that the relationship between counselor and client is important and crucial for therapeutic progress (e.g., Norcross & Wampold, 2011), little research has been done on the experiences of counselors within the therapeutic relationship. Vulnerability has been noted as an important component of growth-fostering relationships (e.g., Jordan, 2008), however research is lacking on how counselors experience vulnerability with their clients. Within the field of counseling, men are underrepresented (Michel, Hall, Hays, & Runyan, 2013) and little research exists exploring their unique experiences as counselors. Additionally, due to gender role socialization, men are likely to struggle with …

School Policy And Practice To Tackle A Public Health Problem: Sudden Cardiac Arrest, Leigh Lynn Mcgown-Kauffman

Dissertations

Sudden cardiac arrest (SCA) is a leading cause of death in the United States. While the medical research has exhaustively documented that immediate response directly impacts survival rates in SCA and that schools could be the best catalyst for creating change by bystanders, there is little to no educational research addressing school policy or practices in regards to cardiac emergencies in schools. The purpose of this dissertation was to identify and describe characteristics of the Colorado schools that offer cardiopulmonary resuscitation (CPR) training and onsite automated external defibrillators (AED). Two research questions were answered, Of respondents, what are the characteristics …

The Meaning Of Physical Activity From The Perspective Of Indonesian Immigrant Youth, Caly Setiawan

Dissertations

The purpose of this phenomenological study was to examine what constitutes the experience of physical activity for Indonesian immigrant youth. Fifteen Indonesian young people aged 13 to 18 participated in the study. Data were collected through two sets of interviews. During the first set of interviews, data were gathered about physical activity experiences and the meanings that the youth ascribed to their participation. A second set of interviews were conducted to collect information about the participants’ strategies for engaging Indonesian immigrants in physical activity. Seven purposefully selected participants were the respondents in these interviews. Data were analyzed using a three …

All Families Are Unique: Experiences Of Lesbian-Parented Families, Rachel Tova Gall

Dissertations

This study explored the experiences of families with lesbian mothers and elementary school-aged children residing in metropolitan areas of the United States. This phenomenology aimed to transcend comparative and binary research to include the voices of sexual minorities and children. Eight whole-family interviews were conducted in alignment with the study’s systemic-constructivist approach. A number of themes emerged from the data that were generally consistent with prior research. Mothers were intentional about the communities in which they surrounded themselves, the process of having children, and having discussions with children about potential discrimination. Participants saw themselves as advocates and were typically out …