Digital Commons Network^™

Ketone Body Metabolism Preserves Hepatic Function During Adaptation To Birth And In Overnutrition, David Graham Cotter

Arts & Sciences Graduate Student Theses and Dissertations

Mammalian ketone body metabolism partially oxidizes hepatic acyl-chains to ketone body intermediates, which can serve as alternative fuels in extrahapetic tissues during carbohydrate restricted states. Ketone body production (ketogenesis) occurs primarily in liver, due to hepatocyte-specific expression of the fate committing ketogenic enzyme, mitochondrial 3-hydroxymethylglutaryl-CoA synthase (HMGCS2). In contrast, the fate committing enzyme of ketone body oxidation, mitochondrial Succinyl-CoA:3-oxoacid CoA Transferase (SCOT), is expressed ubiquitously, except in liver. Here I demonstrate novel roles for ketone body metabolism during a classically ketogenic period, the transition to birth, and in a classically `non-ketogenic' state, overnutrition, using novel genetic mouse models, high-resolution measures …

Understanding Escherichia Coli Urinary Tract Infection: A Niche Perspective, Drew Joel Schwartz

Arts & Sciences Graduate Student Theses and Dissertations

Urinary tract infections (UTIs) are among the most common bacterial infections worldwide, costing greater than $2 billion in healthcare costs and lost wages yearly in America alone. The lifetime risk for a woman exceeds 50% with 25-40% of these suffering recurrent infections. Two of the most important risk factors for recurrent UTI are prior UTIs and sexual intercourse. Over 80% of UTIs are caused by uropathogenic Escherichia coli (UPEC), which binds and invades superficial facet cells lining the bladder surface. UPEC expresses extracellular fibers called type 1 pili with a terminal mannose-binding adhesin, FimH, which interacts with mannosylated uroplakin residues …

2015-May-15-Culture And Health Minor To Be Offered Beginning This Fall, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Liver Injury And Fibrosis Induced By Dietary Challenge In The Ossabaw Miniature Swine, Tiebing Liang, Mouhamad Alloosh, Lauren N. Bell, Allison Fullenkamp, Romil Saxena, William G. Van Alstine, Phelan Bybee, Klára Werling, Michael Sturek, Naga Chalasani, Howard C. Masuoka

Department of Comparative Pathobiology Faculty Publications

Background Ossabaw miniature swine when fed a diet high in fructose, saturated fat and cholesterol (NASH diet) develop metabolic syndrome and nonalcoholic steatohepatitis (NASH) characterized by liver injury and fibrosis. This study was conducted to further characterize the development of NASH in this large animal model. Methods Ossabaw swine were fed standard chow (control group; n = 6) or NASH diet (n = 6) for 24 weeks. Blood and liver tissue were collected and liver histology were characterized at 0, 8, 16 and 24 weeks of dietary intervention. Hepatic apoptosis and lipid levels were assessed at week 24. Results The …

Extraction From The Essence Of Pure Power, Michael A. Helms

Graduate School of Art Theses

This thesis examines the intersections of bodybuilding and performance through a masculine lens. Much like theater, the body builder is activated by staging. In an investigation of its history and a sampling of its theories, we can challenge the hyper-masculine identity which is supported through the gym culture and gender constructs. The arena of the gym contains cues contributing to the artworks listed, and the icons of the gym itself are brought into the studio to transform not only the objects, but the actions themselves. The work challenges the ideals surrounding the superhero, godlike persona cultivated through media tropes. These …

Concerns Of Elementary School Leaders And Teachers When Implementing A Common Core Aligned Mathematics Program, Leela J. George

Dissertations - ALL

The purpose of this study is twofold: first, the research is an investigation of the concerns of school leaders and teachers when implementing a Common Core Learning Standards-aligned elementary mathematics curriculum in an age of accountability and reform; second, this research aims to identify the interventions that school leaders employ in response to the concerns of teachers.

This is a mixed methods study using the Concerns-Based Adoption Model (CBAM). Specifically, the Stages of Concern Questionnaire (SoCQ) and the Change Facilitator Stages of Concern Questionnaire (CFSoCQ) were administered three times during the initial year of implementation of a new mathematics program …

Esc, Craig E. Branum

LSU New Orleans Theses and Dissertations

My artwork is about the impact of the digital revolution on every aspect of life, such as relationships, war, and self image. I explore this in the creation of sculptures that represent abstracted globes or video game worlds, digital animations concerning the virtual and simulated, and prints as allegories for embodied post-human experience. The visual themes of my work are bitmapped patterns, early computer graphics, and twenty-sided dice.

Spatial Features Of Labor Markets And Links To The Housing Market, Nuno Abreu Faro E Mota

Dissertations - ALL

This dissertation comprises three papers on spatial features of labor markets and links to the housing market. The first two papers look at how a local parental leave policy and the neighborhood in which one resides can influence women's decision to work. One paper shows that New Jersey's 2009 family leave insurance program induces women to remain employed following childbirth. The other reveals that, for women, having other women with similar aged children to yours among your closest neighbors makes you emulate their work behavior. The final paper analyzes how seasonality in occupational employment via either monthly or business-cycle induced …

Rural Primary Health Care Providers' Response To Intimate Partner Violence And Survivors' Perceptions Of Helpfulness, Annah Bender

Arts & Sciences Graduate Student Theses and Dissertations

Intimate partner violence (IPV) affects the health and mental health of many women in the United States, with some estimates projecting that one in three women will experience physical, sexual, and/or psychological abuse from a current or former partner during their lifetimes (National Intimate Partner and Sexual Violence Survey [NISVS], 2011). The problems many survivors of IPV face as they attempt to secure help and establish a life free from violence are numerous and include housing, legal, employment, medical, and other domains. Such problems are frequently compounded for survivors residing in rural areas of the U.S., where access to social …

Urban Herders: An Archaeological And Isotopic Investigation Into The Roles Of Mobility And Subsistence Specialization In An Iron Age Urban Center In Mali, Abigail Chipps Stone

Arts & Sciences Graduate Student Theses and Dissertations

This dissertation investigates the relationship between mobility and urbanism in an Iron Age West African city. Isotopic and archaeological evidence reveal complex relationships among mobility, sedentism, and the livestock economy of Jenné-jeno, one of the earliest and best known urban systems in sub-Saharan Africa (occupied ca. 250 BC to AD 1400). Drawing on excavations at the ancient city of Jenné-jeno and those conducted at two neighboring sites (Tato à Sanouna and Thièl), and on serial, intra-tooth isotopic analysis (87Sr/86Sr, 13C, 18O) of cattle, sheep, and goat teeth, this analysis shows that multiple populations involved in animal husbandry, from seasonally mobile …

Refugee Health And The Kentucky Global Health Center, Rahel Bosson, Ruth M. Carrico

Journal of Refugee & Global Health

In this University of Louisville Grand Rounds lecture, Drs. Rahel Bosson and Ruth Carrico give an overview of the real struggle of the refugee population and provide an update of the current state of refugee health in Kentucky.

They also provide an overview of the Global Health Initiative at University of Louisville, which includes the follow programs: HIV/AIDs, Refugee Health and Immunization, Vaccine and International Travel and Global Health Research Support.

The talk concludes looking to the future with a comprehensive Global Health Center composed of improving refugee orientation and EMR, healthcare worker education, developing guidelines, and bettering our surveillance …

Sports And Somali Girls: Increasing Participation And Acculturation, Mandy Rose Franz

School of Education and Leadership Student Capstone Theses and Dissertations

The research questions addressed in this project are: What are the current barriers in high schools in a large mid-­‐western city that prevent Somali girls from joining high school sports? Which local programs have been successful in recruiting Somali girls and how has this been accomplished? What are some solutions to overcoming obstacles that are preventing involvement? The motivating factor for this capstone was to provide recommendations to coaches and athletic directors of high schools on how to incorporate more of their Somali female population into their athletic programs. The results of this study suggest that there are specific actions …

Demystifying Open Access Workshop, Rose Fortier, Heather G. James, Martha G. Jermé, Patricia Berge, Rosemary Del Toro

Library Events and Research Institutes

Among the avenues for sharing research and scholarship, open access journals offer an increasingly viable and important option. However, it can be challenging not only to identify these journals but also to evaluate their quality and reach, as well as to weigh the benefits of publishing in them.

To help demystify this process, Raynor Memorial Libraries offered a workshop on evaluating open access journals. Aimed at faculty, graduate students, and others interested in publishing their academic work, the workshop offered an overview of current open access options for sharing research, criteria to help assess the rigor and reliability of open …

Factors Contributing To Registered Nurse Job Satisfaction In The Nursing Home, Michael Shipley

Seton Hall University Dissertations and Theses (ETDs)

Over the next several years the aging population will increase the number of patients suffering from chronic illness. A sicker aging population, coupled with changes in healthcare reimbursement will require nursing homes to admit sicker patients for shorter lengths of stays. To meet the needs of the increased number of chronic patients and those patients with higher acuities, nursing homes will require more skilled, registered nurses. Registered nurses (RNs) are the linchpin to providing high-quality care in the healthcare environment and especially in nursing homes.

Understanding the factors of RN job satisfaction in the nursing home is important in increasing …

Identification Of Species In Commercially Sold Game Meats Using Dna Barcoding, Charles Quinto, Rebecca Tinoco, Rosalee S. Hellberg

Student Scholar Symposium Abstracts and Posters

Game meats represent a multibillion dollar industry in the United States with high economic incentives associated with species substitution and mislabeling. However, there is currently a lack of information regarding the prevalence of mislabeled game meat on the U.S commercial market. The purpose of this study was to conduct a market survey of whole-cut game products sold within the United States to identify incidences of mislabeling using DNA barcoding. Identified species were also examined for classification as a threatened or endangered species. Fifty-four whole-cut game meat samples were collected from online distributors in the United States and sequenced across the …

Removal Of Pb And H2s From Acs Test Procedure For Meta-Phosphoric Acid, Christopher Atlas, Ron Lacock

Student Scholar Symposium Abstracts and Posters

In the pursuit of green chemistry, adequate substitutes for lead acetate and hydrogen sulfide were investigated for use in the ACS test procedure for stabilizer in meta-phosphoric acid. In the current ACS procedure lead acetate is used to form insoluble lead phosphate. In order to remove lead from the solution lanthanum chloride was investigated with positive results. Hydrogen Sulfide is currently used to precipitate lead by forming insoluble lead sulfide. Several substitutes including oxalic acid and sulfuric acid were investigated. Preliminary testing showed that lanthanum chloride and oxalic acid are sufficient in precipitating phosphate and lead out of the sample …

The Effects Of A Caloric Restrictive Diet On Bone Mineral Density And Bone Strength In Male And Female Rats, Haley Folta

Student Scholar Symposium Abstracts and Posters

The purpose of this study was to determine the existence of sex differences following a 40% caloric restrictive diet and its impact on tibial bone mineral density (BMD) and bone strength between male and female rats. Thirty-two, six-week old Sprague Dawley rats (16 males and 16 females) were randomly divided into an ad libitum fed control group (MC, n=8 and FC, n=8) and a pair fed diet group placed on the 40% caloric restriction (MD, n=8 and FD, n=8) for a 6 week period. The caloric restrictive diet was equivalent to the normal fed diet in vitamin and mineral content …

Assessing Water Quality In The Gulf Of Mexico Using Remote Sensing Data., Alliyah Thomas

Student Scholar Symposium Abstracts and Posters

Hypoxia, or oxygen depletion, is a process that occurs in conjunction with eutrophication. In hypoxic conditions the dissolved oxygen levels in the water column sink to unlivable conditions for the marine organisms causing them to flee or die. Despite efforts of improvement, the annual summer Gulf of Mexico dead zone continues to be a serious threat to aquatic ecosystems. The 2012 smaller than usual dead zone was a false indicator of future improvement. The 2012 dead zone decrease was connected to the drought and inability of large amounts of runoff to flow into the gulf. Water quality analysis was done …

Effect Of Phytosanitary Irradiation On The Quality Of Chandler Pummelo (Citrus Maxima (Burm.) Merr.), Akanksha Jain, J.J. Ornelas-Paz, Karina Rodriguez, Anuradha Prakash

Student Scholar Symposium Abstracts and Posters

In this study, we evaluated the chemical and physiological effect of low-dose gamma irradiation on the post-harvest quality of Chandler Pummelos (Citrus maxima (Burm.) Merr.), an emerging crop of interest in the U.S. Chandler pummelos from a local grower in California were irradiated at target doses of 150 Gy and 1000 Gy. Irradiated and untreated pummelos were stored at 12 °C for 3 weeks and at 20 °C for the 4th week to reflect three weeks of sea shipment at ideal temperature for storage of pummelos and an additional week of retail under ambient conditions. Irradiation reduced hardness of the …

Combining Systems Methodologies To Reduce Allergen-Related Food Recalls, Jill Marie Sweney

Dissertations and Theses

The risk of poor food safety is a major focus for managers in the food manufacturing industry. Despite industry-led and regulatory efforts to improve the overall food safety of US packaged consumer foods, product recalls and market withdrawals are increasing. This is especially true for the most frequent cause for food recall: the undeclared allergen. With industry trends leaning toward adoption of third-party food safety management certifications, a popular food safety code from the Safe Quality Foods Institute is evaluated using Systems Analysis. Three changes to the food safety code are proposed to address three of the top causes for …

Running On Empty: A Comparison Of Marathon And Ultramarathon Race Preparation, K M. Jones, K E. Jones, J A. Smeltz, B T. Jensen, J S. Lynn

International Journal of Exercise Science: Conference Proceedings

Please view abstract in the attached PDF file

Board Of Trustees Minutes Regular Meeting May 13, 2015, Central Washington University

Board of Trustees Meeting Minutes

No abstract provided.

What Carries On: Drafting, Revising, And Attention To Craft In Young Adult Fiction, Briana Mcdonald

Honors Program Theses and Projects

No abstract provided.

Volume 52, Number 39: May 13, 2015, University Of North Dakota

University Letter Archive

No abstract provided.

Nurses' Self-Efficacy For Managing Elder Abuse, Alana Anderson

Nursing Theses and Dissertations

Elder abuse is a serious issue that negatively affects physical and mental health in a significant portion of the older population. Abuse of older adults is not adequately detected or reported. Nurses have frequent contact with older victims of abuse, providing them the opportunity to play a significant role in detecting, reporting, and intervening in such cases. Nurses are reluctant to intervene due to lack of education on elder abuse and lack of self-efficacy in their ability to properly manage elder abuse. This quantitative, descriptive study was designed to determine whether educational content on elder abuse, perceived capability, and self-efficacy …

Five Undergrads Receive Coveted Gilman International Scholarship, Jeanne Sokolowski

UNH Today Archive

No abstract provided.

Recent Studies On Nutrition And Parkinson’S Disease Prevention: A Systematic Review, Ann Gaba

Publications and Research

Introduction: Parkinson’s disease (PD) is a chronic progressive movement disorder, affecting primarily people over sixty years of age. With aging populations, some estimates indicate as many as nine million people will be impacted by this disease by 2030. Thus it is imperative to identify means of prevention, delay of onset, and management of symptoms. Many elements of diet and nutrition have been investigated to accomplish these goals. This review will examine recent studies of potential diet and nutrition factors and PD incidence.

Methods: A PubMed Search was conducted using the keywords “Parkinson, prevention and nutrition”, and “Parkinson, prevention, and diet.” …

Spartan Daily, May 13, 2015, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 144, Issue 42

Potential Of The Desert Locust Schistocerca Gregaria (Orthoptera: Acrididae) As An Unconventional Source Of Dietary And Therapeutic Sterols, Xavier Cheseto, Serge Philibert Kuate, David P. Tchouassi, Mary Ndung'u, Peter E.A. Teal, Baldwyn Torto

All Peer-Reviewed Publications

Insects are increasingly being recognized not only as a source of food to feed the ever growing world population but also as potential sources of new products and therapeutic agents, among which are sterols. In this study, we sought to profile sterols and their derivatives present in the desert locust, Schistocerca gregaria, focusing on those with potential importance as dietary and therapeutic components for humans. Using coupled gas chromatography-mass spectrometry (GC-MS), we analyzed and compared the quantities of sterols in the different sections of the gut and tissues of the locust. In the gut, we identified 34 sterols which showed …

Social Communication Of Predator-Induced Changes In Drosophila Behavior And Germ Line Physiology, Balint Z. Kacsoh, Julianna Bozler, Mani Ramaswami, Giovanni Bosco

Dartmouth Scholarship

Behavioral adaptation to environmental threats and subsequent social transmission of adaptive behavior has evolutionary implications. In Drosophila, exposure to parasitoid wasps leads to a sharp decline in oviposition. We show that exposure to predator elicits both an acute and learned oviposition depression, mediated through the visual system. However, long-term persistence of oviposition depression after predator removal requires neuronal signaling functions, a functional mushroom body, and neurally driven apoptosis of oocytes through effector caspases. Strikingly, wasp-exposed flies (teachers) can transmit egg-retention behavior and trigger ovarian apoptosis in naive, unexposed flies (students). Acquisition and behavioral execution of this socially learned behavior …