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Wsu Research News, Summer 2015, Office Of Research And Sponsored Programs, Wright State University

WSU Research News

A sixteen page newsletter of the WSU Research News. The WSU Research News was published monthly beginning in June of 1968 and issued by the Office of Research Development. This newsletter was created to provide information to the WSU faculty about the availability of outside funds for research and educational programs, new developments that may affect availability of funds, and general information on research and educational activities at Wright State University.

Implications Of Underlying Pathophysiology Of Osteomyelitis In Diabetics For Nursing Care, Danielle Spencer

Nursing Student Class Projects (Formerly MSN)

Osteomyelitis is an infection of the bone caused by either bacteria, fungi, parasites, viruses or mycobacteria (McCance, et. al., 2014). The infection can enter bone either through an outside source or through the blood from a blood borne infection (McCance, et. al., 2014). The most common bacteria involved with osteomyelitis is Staphylococcus aureus (Hatzenbuehler & Pulling, 2011, p. 1027). Recently, at Dublin Methodist Hospital there has been an increase in the number of osteomyelitis cases in chronic uncontrolled diabetic patients requiring below the knee amputations. Two of the cases specifically were linked to chronic diabetic foot ulcers. Each of these …

Clostridium Difficile, Kristen Johnson

Nursing Student Class Projects (Formerly MSN)

Clostridium difficile (CD) is an infectious disease that has a direct impact on our healthcare resources. “Clostridium difficile, an anaerobic, spore forming, toxin-forming, gram-positive bacillus, has become the leading cause of health care—associated infectious diarrhea (Walters & Zuckerbraun, 2014, p. 329).” I chose this topic because CD is a hypervirulent organism that is not only affecting hospitalized patients but is now emerging as a community acquired infection. Healthcare treatments and costs are on the rise due to persistent and recurrent CD infections. Understanding the pathogenesis, risk factors, diagnostic testing, and management strategies are important in reducing the spread of CD …

Growing South Dakota (Summer 2015), College Of Agriculture &. Biological Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Exciting New Era Underway: New Facilities & New Degree Offerings Coming To Fruition
[Page] 5 USDA Report Touts Agriculture Among Best Fields For College Grads
[Page] 6 Critical Need: Essential Services Of ADRDL Need Support For Modernized Facility
[Page] 8 Quarterly Colloquium: State's Ag Leaders Collaborate
[Page] 9 Profiles In Leadership: Developing A Museum To Enrich And Transform Lives
[Page] 10 Productive Partnerships: Collaboration Between Producers & Researchers Guides Research Farm Efforts
[Page] 12 Coordinated Effort: SDSU's John Ball Serves Dual Role To Benefit South Dakota's Trees
[Page] 14 Progressive Perspective: Dan Oedekoven Reflects On Extension's Evolution
[Page] …

College Of Nursing, Dave Graves, Emily Weber

College of Nursing Magazine

Features

Celebrating Excellence — The College of Nursing honors leaders during 80th anniversary
[Page] 2 — Photo gallery of honorees.
[Page] 6 — A brief look at the college’s history.
[Page] 12 — The first four-year class.
[Page] 14 — The gala’s honorees.
[Page] 23 — Class of 1965 gives back.
[Page] 24 — Alumni profiles.

Department news
[Page] 28- Faculty and professional staff publications.
[Page] 30- Faculty and student awards and honors.
[Page] 31- Deans’ distinguished lecture.
[Page] 32- College honors.

Alumni news
[Page] 32- In memoriam.
[Page] 33- Stacey Tait-Goodale Thank you for making the 80th Gala a …

The College Of Pharmacy, South Dakota State University

Jackrabbits Script and Scope (Formerly called College of Pharmacy and Allied Health Professions Magazine)

[Page] 2 Master of Public Health College of Pharmacy joins forces with other colleges and USD to offer Master of Public Health degree.
[Page] 4 Father of Tamoxifen V. Craig Jordan visits State as Francis Miller Distinguished Lecturer.
[Page] 6 Hometown satisfaction Dedication to hometown and residents earns Travis Anderberg ’04 the 2015 South Dakota Retailer of the Year.
[Page] 10 Excellence Tadd Hellwig named college’s outstanding scholar while Debra Farver chosen college’s teacher of the year.
[Page] 12 Building better mouse models Markl Faculty Scholar Wenfeng An’s research using mouse models lands two National Institutes of Health grants.
[Page] …

Neutropenia In Congenital And Adult Babesiosis, Gary P. Wormser, Patrick Villafuerte, Sheila M. Nolan, Guiqing Wang, Robert G. Lerner, Kirsten L. Saetre, Mazen H. Maria, John A. Branda

NYMC Faculty Publications

OBJECTIVES: Anemia and thrombocytopenia are expected hematologic abnormalities in patients with acute babesiosis, whereas neutropenia (defined as an absolute neutrophil count of ≤1,800 neutrophils/μL for adults and <1,200 neutrophils/μL for infants) is not usually considered a feature of this infection. We studied the frequency with which neutropenia occurs in congenital and adult cases of babesiosis. METHODS: The frequency of neutropenia in cases of congenital babesiosis was determined based on a literature review and on the findings in an unreported case. The frequency of neutropenia in adult patients was assessed based on a review of the medical records of 51 patients who were diagnosed with babesiosis between 2010 and 2013 at two medical centers in the Northeastern United States. RESULTS: Four (80%; 95% confidence interval [CI], 36%-98%) of five infants with congenital babesiosis whose neutrophil count was reported were neutropenic. Among 51 adult cases with babesiosis, 11 (22%; 95% CI, 12%-35%) were neutropenic on clinical presentation, and seven others developed neutropenia over the next 1 to 21 days. Thus, a total of 18 (35%; 95% CI, 24%-49%) of the adult patients with babesiosis had neutropenia. CONCLUSIONS: Neutropenia appears to be a common finding in infants with congenital babesiosis and is also observed not infrequently in adults with this infection.

Benchmarks 2015, July 10, The Rockefeller University

BenchMarks 2015

BenchMarks. Friday, July 10, 2015

The community newsletter of The Rockefeller University

BenchMarks is published monthly and is distributed on the campus of The Rockefeller University. It produced by the Office of Communications and Public Affairs

Doctalk Newsletter May/June 2015, Maine Department Of Corrections

DOCTalk Newsletter

In this issue:

• Snowshoe Chair made at Charleston goes to Washington DC
• Plant a Seed Project in Region 2 - Adult
• Honor Guard Academy

Differences In Health-Related Behaviors And Attitudes Between Urban, Rural, And Isolated Households In Western West Virginia, Michael Newsome Phd, Tim Hazelett, Monika Sawhney Phd, Msw

Economics Faculty Research

This study uses data from a 2013 survey of 275 randomly sampled households across nine counties in western West Virginia to examine the significant differences between the health behaviors and attitudes of rural and isolated populations. The results show that age, education, and income are significant factors in explaining differences in health-related behaviors and attitudes for all urban, rural and isolated respondents. However, after controlling for socio-demographic differences, isolation is found to have only a few significant effects, and some of the effects run counter to stereotypes of isolated populations. Rural respondents are significantly more likely than isolated respondents to …

A Confirmed Case Of Toxic Shock Syndrome Associated With The Use Of A Menstrual Cup, Michael A. Mitchell, Steve Bisch, Shannon Arntfield, Seyed M. Hosseini-Moghaddam

Paediatrics Publications

Menstrual cups have been reported to be an acceptable substitute for tampons. These flexible cups have also been reported to provide a sustainable solution to menstrual management, with modest cost savings and no significant health risk. The present article documents the first case of toxic shock syndrome associated with the use of a menstrual cup in a woman 37 years of age, using a menstrual cup for the first time. Toxic shock syndrome and the literature on menstrual cups is reviewed and a possible mechanism for the development of toxic shock syndrome in the patient is described.

Unm Pathology Pathfinder Summer 2015, Unm Department Of Pathology

Newsletters

No abstract provided.

Predicting Risk Of End-Stage Liver Disease In Antiretroviral-Treated Hiv/Hepatitis C Virus-Coinfected Patients, Vincent Lo Re Iii, Michael J. Kallan, Janet P. Tate, Joseph K. Lim, Matthew Bidwell Goetz, Cynthia L. Gibert, +10 Additional Authors

Medicine Faculty Publications

Background. End-stage liver disease (ESLD) is an important cause of morbidity among HIV/hepatitis C virus (HCV)-coinfected patients. Quantifying the risk of this outcome over time could help determine which coinfected patients should be targeted for risk factor modification and HCV treatment. We evaluated demographic, clinical, and laboratory variables to predict risk of ESLD in HIV/HCV-coinfected patients receiving antiretroviral therapy (ART).

Methods. We conducted a retrospective cohort study among 6,016 HIV/HCV-coinfected patients who received ART within the Veterans Health Administration between 1997 and 2010. The main outcome was incident ESLD, defined by hepatic decompensation, hepatocellular carcinoma, or liver-related death. Cox regression …

Levels Of 8-Oxodg Predict Hepatobiliary Pathology In Opisthorchis Viverrini Endemic Settings In Thailand., Prasert Saichua, Anna Yakovleva, Christine Kamamia, Amar R. Jariwala, Paul J. Brindley, Jeffrey M. Bethony, + 8 More

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Opisthorchis viverrini is distinct among helminth infections as it drives a chronic inflammatory response in the intrahepatic bile duct that progresses from advanced periductal fibrosis (APF) to cholangiocarcinoma (CCA). Extensive research shows that oxidative stress (OS) plays a critical role in the transition from chronic O. viverrini infection to CCA. OS also results in the excision of a modified DNA lesion (8-oxodG) into urine, the levels of which can be detected by immunoassay. Herein, we measured concentrations of urine 8-oxodG by immunoassay from the following four groups in the Khon Kaen Cancer Cohort study: (1) O. viverrini negative individuals, (2) …

Using Whole Genome Analysis To Examine Recombination Across Diverse Sequence Types Of Staphylococcus Aureus, Elizabeth M. Driebe, Jason W. Sahl, Chandler Roe, Jolene R. Bowers, James M. Schupp, Lance B. Price, +11 Additional Authors

Environmental and Occupational Health Faculty Publications

Staphylococcus aureus is an important clinical pathogen worldwide and understanding this organism's phylogeny and, in particular, the role of recombination, is important both to understand the overall spread of virulent lineages and to characterize outbreaks. To further elucidate the phylogeny of S. aureus, 35 diverse strains were sequenced using whole genome sequencing. In addition, 29 publicly available whole genome sequences were included to create a single nucleotide polymorphism (SNP)-based phylogenetic tree encompassing 11 distinct lineages. All strains of a particular sequence type fell into the same clade with clear groupings of the major clonal complexes of CC8, CC5, …

2014-2015 - Graduate Council Annual Report, College Of Graduate And Continuing Studies, East Tennessee State University

Graduate Council Agendas and Minutes

No abstract provided.

"The Four Horseman Of The Late Capitalist Apocalypse": U.S. Comic Books, Ideology, And Trauma In Post-9/11 Society, Kathryn Manis

Art & Art History ETDs

In the contemporary United States apocalypse, dystopia, and catastrophe are commonplace. Indeed, both the increasing presence of fictional apocalypse in art and popular culture and the tone of apocalypticism in U.S. political, environmental, and social rhetorics, have been noted by writers and thinkers from a wide range of fields. Scholars of neoliberalism in particular have traced this popularity to the economic and political realities of late-capitalism and the ideological contradictions embedded in the evolution of capitalism to its current, immersive iteration. What has gone undiscussed, however, is the relationship of this anxious preoccupation to a prevailing, national condition; a condition …

The Role Of Community Pharmacy-Based Vaccination In The Usa: Current Practice And Future Directions, Albert Bach, Jeffery A. Goad

Pharmacy Faculty Articles and Research

Community pharmacy-based provision of immunizations in the USA has become commonplace in the last few decades, with success in increasing rates of immunizations. Community pharmacy-based vaccination services are provided by pharmacists educated in the practice of immunization delivery and provide a convenient and accessible option for receiving immunizations. The pharmacist's role in immunization practice has been described as serving in the roles of educator, facilitator, and immunizer. With a majority of pharmacist-provided vaccinations occurring in the community pharmacy setting, there are many examples of community pharmacists serving in these immunization roles with successful outcomes. Different community pharmacies employ a number …

Ebola, Quarantine, And Flawed Cdc Policy, Robert Gatter

University of Miami Business Law Review

The CDC’s Interim Guidance for Monitoring and Movements of Persons with Potential Ebola Virus Exposure is deeply flawed because it disregards the science of Ebola transmission. It recommends that officials quarantine individuals exposed to the virus but who do not have any symptoms of illness, ignoring the fact that only those with Ebola symptoms can communicate the virus to others. Consequently, any quarantine order based on the Guidelines is surely unconstitutional and illegal under most states’ public health statutes—as exemplified by the State of Maine’s failed petition to quarantine Nurse Kaci Hickox in October 2014. This article examines the Guidance …

Legal, Operational, And Practical Considerations For Hospitals And Health Care Providers In Responding To Communicable Diseases Following The 2014 Ebola Outbreak, Jane Jordan, Greg Measer, Asha Agrawal, James G. Hodge Jr.

University of Miami Business Law Review

This article analyzes some of the potential issues that may arise during epidemics or other public health emergencies. It specifically focuses on legal and operational preparedness experiences at Emory University during the 2014 Ebola crisis. Emory University Hospital was the first health care facility in the U.S. to treat patients diagnosed with Ebola Viral Disease (EVD). Although EVD has particularly frightening symptoms and a high mortality rate, its containment and treatment implicate similar legal, practical, and operational issues as other highly infectious and communicable diseases. These issues include laws related to: isolation and quarantine; travel restrictions; duties to treat highly …

Carnival Cruise Ships In South Carolina: Nuisance And Cruise Control, William H. Yarborough

South Carolina Law Review

No abstract provided.

Schistosomes Of Nepal, Ramesh Devkota

Biology ETDs

Globally, digenetic trematodes called schistosomes (Family Schistosomatidae) have enormous public and veterinary health significance because they cause debilitating and chronic infections collectively called schistosomiasis. Schistosomes have a life cycle featuring a bird or mammal definitive host in which adult worms are found, and freshwater snail intermediate hosts in which larval stages are found and free-swimming cercariae are produced which infect the definitive host. Although schistosomes are known to be common in tropical and subtropical Asia, their presence in Nepal, a small south Asian country situated between India and China, was almost completely unknown at the beginning of this study. Consequently, …

An Insight Into The Sialome Of The Lone Star Tick, Ambylomma Americanum, With A Glimpse On Its Time Dependent Gene Expression, Shahid Karim, José M.C. Ribeiro

Faculty Publications

Hard ticks feed for several days or weeks on their hosts. Blood feeding is assisted by tick saliva, which is injected in the host skin regularly, alternating with blood ingestion. Tick saliva contains hundreds or thousands of different peptides and other bioactive compounds that assist feeding by inhibiting their hosts’ blood clotting, platelet aggregation, vasoconstriction, as well as pain and itching. Immunomodulatory and antimicrobial peptides are also found in tick saliva. Molecular characterization of tick salivary compounds, or its sialome (from the Greek sialos = saliva), helps identification of possible antigens that might confer anti-tick immunity, as well as identifying …

Perceptions And Knowledge Regarding Antimicrobial Stewardship Among Clinicians In Jeddah, Saudi Arabia, Sameer E. Al-Harthi, Lateef M. Khan, Abdel-Moneim M. Osman, Mai A. Alim, Omar I. Saadah, Abdulrehman A. Almohammadi, Faheem M. Khan, Fatemah O. Kamel

Saudi Medical Journal

Objectives: To understand the perceptions, attitude, and prescribing practices of clinicians regarding antimicrobial resistance (AMR). Methods: A multidisciplinary cross-sectional study comprising 447 clinicians of university, public, and private hospitals of Jeddah, Saudi Arabia was carried out from August to October 2014 using a self-administered questionnaire. Results: Interestingly, 33% of the general physicians yielded to patient/parent’s demand for the choice of antimicrobials (AMs) as compared with only 13.2% of the residents, and 4.3% of the specialists. In addition, expensive AMs are more often prescribed by the general physician (70.4%) in comparison with 26.4% residents and 30.4% of the specialists. However, no …

New Approach To Develop Ultra-High Inhibitory Drug Using The Power Function Of The Stoichiometry Of The Targeted Nanomachine Or Biocomplex, Dan Shu, Fengmei Pi, Chi Wang, Peng Zhang, Peixuan Guo

Pharmaceutical Sciences Faculty Publications

AIMS: To find methods for potent drug development by targeting to biocomplex with high copy number.

METHODS: Phi29 DNA packaging motor components with different stoichiometries were used as model to assay virion assembly with Yang Hui's Triangle [Formula: see text], where Z = stoichiometry, M = drugged subunits per biocomplex, p and q are the fraction of drugged and undrugged subunits in the population.

RESULTS: Inhibition efficiency follows a power function. When number of drugged subunits to block the function of the complex K = 1, the uninhibited biocomplex equals q(z), demonstrating the multiplicative effect of stoichiometry on inhibition with …

Oncolog, Volume 60, Number 07, July 2015, Kathryn L. Hale, Bryan Tutt, K. Stuyck

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Emergency Care for Cancer Patients: Medical problems that may seem routine in patients without cancer often mean something different or have a different cause in cancer patients and may be much more serious, requiring urgent treatment. Managing these problems promptly and effectively is a challenge faced by all cancer centers.
• Immunotherapy Trials Offer Hope to Patients with High-Risk or Metastatic Cancer: Although the cure rate for the breast cancer has risen steadily in recent decades, recurrent or metastatic disease remains difficult to control. To fight metastatic breast cancer and forestall the recurrence of high-risk primary disease, researchers at The University …

Airborne Infection In Healthcare Environments: Implications To Hospital Corridor Design, Ehsan Mousavi

Department of Construction Engineering and Management: Dissertations, Theses, and Student Research

Several studies have linked nosocomial transmission airborne diseases to airflow in healthcare settings. Quasi-experimental methods are developed to observe the aerodynamic transport behavior of synthetic respiratory particles in corridors of a hospital. Computational models, validated by experimental results, are then developed to explore the spatial relationships of supply-exhaust air ventilation in patient corridors. The aim of this study is to determine optimal HVAC design strategies to contain and remove airborne contaminants in healthcare environments.

In addition to occupant comfort, hospital HVAC systems are designed to provide ventilation and directional airflow to contain, dilute and remove contaminants including airborne disease. Of …

A Comparative Study Of The Utility Of New Media Technologies And Power Distance In Doctor-Patient Communication In The Philippines And The United States, Bessie Lee Lawton, Meghan Mahoney, Lukas Pelliccio

Communication and Media Faculty Publications

No abstract provided.

Comparison Of Different Modulators That Affect Macrophage Activation In Vitro, Alda Alexa Díaz Pérez

Graduate Theses and Dissertations

Inflammation is known as a mechanism to regulate and control infections as well as promote tissue repair. Macrophages (Mф) are known to be a major cell type in the initiation, sustainability and resolution of inflammation. Moreover, Mф are essential for the remodeling process that is also known as the wound healing response. The objective of this research was to compare five modulators (acetylsalicylic acid (ASA), dexamethasone (DEX), prostaglandin E2 (PGE2), iloprost, and resolvin D1 (RvD1) for their anti-inflammatory effects on macrophages in vitro. Then, Mф phenotype in terms of gene expression and secreted cytokine response was determined. Our study compared …

Child Marriage Legislation In The Asia-Pacific Region, Elisa Scolaro, Aleksandra Blagojevic, Brigitte Fillion, Venkatraman Chandra-Mouli, Lale Say, Joar Svanemyr, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Child marriage is a human rights violation that robs a girl of her childhood, puts her health, growth, and development at risk, disrupts her education, limits her opportunities for empowerment and social development, and increases her risk of exposure to violence and abuse (for a review of the evidence on the negative effects of child marriage on girls and their children, see Parsons et al. 2015, in this issue). While child marriage is not mentioned specifically in the 1989 Convention on the Rights of the Child (CRC), the Convention does contain a provision requiring governments to abolish “traditional practices prejudicial …