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From Conceptual Pluralism To Practical Agreement On Policy: Global Responsibility For Global Health, Audrey Chapman

UCHC Articles - Research

Background

As the human cost of the global economic crisis becomes apparent the ongoing discussions surrounding the post-2015 global development framework continue at a frenzied pace. Given the scale and scope of increased globalization moving forward in a post-Millennium Development Goals era, to protect and realize health equity for all people, has never been more challenging or more important. The unprecedented nature of global interdependence underscores the importance of proposing policy solutions that advance realizing global responsibility for global health.

Discussion

This article argues for advancing global responsibility for global health through the creation of a Global Fund for Health. …

Running And Tumbling With E. Coli In Polymeric Solutions, Alison E. Patteson, Arvind Gopinath, Mark Goulian, Paulo E. Arratia

Physics - All Scholarship

Run-and-tumble motility is widely used by swimming microorganisms including numerous prokaryotic and eukaryotic organisms. Here, we experimentally investigate the run-and-tumble dynamics of the bacterium E. coli in polymeric solutions. We find that even small amounts of polymer in solution can drastically change E. colidynamics: cells tumble less and their velocity increases, leading to an enhancement in cell translational diffusion and a sharp decline in rotational diffusion. We show that suppression of tumbling is due to fluid viscosity while the enhancement in swimming speed is mainly due to fluid elasticity. Visualization of single fluorescently labeled DNA polymers reveals that the …

Student Uses Internship To Study Algae As Renewable Energy, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Routine Vs. Clinically Indicated Peripherally Inserted Intravenous Catheter Changes, Juliet Hahn Bsn, Rn, Zinah Heisel Bsn, Rn, Devin Pond Bsn. Rn

Patient Care Services / Nursing

No abstract provided.

Interrater Variability In Identifying Ventilator Associated Pneumonia Using Six Different Definitions, Ahmad Nusair, Md, Balwinder Singh, Md, Ms., Shifang Ding, Md, Phd., Ognjen Gajic, Md, Guangxi Li, Md

Marshall Journal of Medicine

Objective

There is no widely accepted standard definition for Ventilator Associated Pneumonia (VAP). The reliability of the current definitions in use remains controversial. Our objective was to assess the reliability of six commonly used VAP definitions: The Loose, The Rigorous, The Modified Clinical Pulmonary Infection Score (CPIS), The Canadian Critical Care Trials Group (CCCTG), The International Sepsis Forum Consensus (ISFC) and The Center for Disease Control and Prevention (CDC).

Design

We examined the electronic health records of all the consecutively admitted adult patients at our institution who received invasive mechanical ventilation (IMV) for ≥ 48 hours, from January 2006 through …

2015-10-27-Professor Receives Nih Funds To Research Liver Disease, University Marketing And Communications, East Tennessee State University

Accent [newsletter]

No abstract provided.

Volume 89, Issue 5 (2015)

Obiter Dicta

No abstract provided.

Dendritic Cell Autophagy Contributes To Herpes Simplex Virus-Driven Stromal Keratitis And Immunopathology, Yike Jiang, Xiaotang Yin, Patrick M. Stuart, David A. Leib

Dartmouth Scholarship

Herpetic stromal keratitis (HSK) is a blinding ocular disease that is initiated by HSV-1 and characterized by chronic inflammation in the cornea. Although HSK immunopathology of the cornea is well documented in animal models, events preceding this abnormal inflammatory cascade are poorly understood. In this study, we have examined the activation of pathological CD4T cells in the development of HSK. Dendritic cell autophagy (DC-autophagy) is an important pathway regulating ma- jor histocompatibility complex class II (MHCII)-dependent antigen presentation and proper CD4T cell activation during infectious diseases. Using DC-autophagy-deficient mice, we found that DC-autophagy significantly and specifically contributes to HSK disease …

Public Health Impact Of Strain Specific Immunity To Borrelia Burgdorferi, Camilo E. Khatchikian, Robert B. Nadelman, John Nowakowski, Ira Schwartz, Michael Z. Levy, Dustin Brisson, Gary P. Wormser

NYMC Faculty Publications

BACKGROUND: Lyme disease, caused by Borrelia burgdorferi, is the most common tick-borne infection in the United States. Although humans can be infected by at least 16 different strains of B. burgdorferi, the overwhelming majority of infections are due to only four strains. It was recently demonstrated that patients who are treated for early Lyme disease develop immunity to the specific strain of B. burgdorferi that caused their infection. The aim of this study is to estimate the reduction in cases of Lyme disease in the United States that may occur as a result of type specific immunity. METHODS: The analysis …

Detection And Characterization Of Mineralo-Organic Nanoparticles In Human Kidneys, Tsui-Yin Wong, Cheng-Yeu Wu, Jan Martel, Cheng-Wei Lin, Fu-Yung Hsu, David M. Ojcius, Paul Y. Lin, John Ding-E. Young

All Dugoni School of Dentistry Faculty Articles

Ectopic calcification is associated with various human diseases, including atherosclerosis, cancer, chronic kidney disease, and diabetes mellitus. Although mineral nanoparticles have been detected in calcified blood vessels, the nature and role of these particles in the human body remain unclear. Here we show for the first time that human kidney tissues obtained from end-stage chronic kidney disease or renal cancer patients contain round, multilamellar mineral particles of 50 to 1,500 nm, whereas no particles are observed in healthy controls. The mineral particles are found mainly in the extracellular matrix surrounding the convoluted tubules, collecting ducts and loops of Henle as …

Hirsutella Sinensis Mycelium Attenuates Bleomycin-Induced Pulmonary Inflammation And Fibrosis In Vivo, Tsung-Teng Huang, Hsin-Chih Lai, Yun-Fei Ko, David M. Ojcius, Ying-Wei Lan, Jan Martel, John Ding-E. Young, Kowit-Yu Chong

All Dugoni School of Dentistry Faculty Articles

Hirsutella sinensis mycelium (HSM), the anamorph of Cordyceps sinensis, is a traditional Chinese medicine that has been shown to possess various pharmacological properties. We previously reported that this fungus suppresses interleukin-1β and IL-18 secretion by inhibiting both canonical and non-canonical inflammasomes in human macrophages. However, whether HSM may be used to prevent lung fibrosis and the mechanism underlying this activity remain unclear. Our results show that pretreatment with HSM inhibits TGF-β1–induced expression of fibronectin and α-SMA in lung fibroblasts. HSM also restores superoxide dismutase expression in TGF-β1–treated lung fibroblasts and inhibits reactive oxygen species production in lung epithelial cells. Furthermore, …

Week Of October 26, 2015, New York Medical College

InTouch

• William Campbell, Ph.D., Longtime, Celebrated NYMC Adjunct Professor, Wins Nobel
• Steven A. Wartman, M.D., Ph.D., M.A.C.P., Announced as 2016 NYMC Commencement Speaker
• Dean Miller Reports on LCME Mock Site Visit
• School of Medicine Launches Personal Accolades and Incidents Reporting (PAIR)
• Medical Student Brian Yum Selected Semi-Finalist in Essay Program
• D.P.T. Students Host Successful Race for Rehab
• NYMC Welcomes BOCES New Visions Health Students
• NYMC Sends Support to Liberia
• SHSP Welcomes New Cohort of Dr.P.H. Candidates

Microhabitat And House Use By Dusky-Footed Woodrats (Neotoma Fuscipes) In Northwestern California: Insight From Trapping Data, Ted J. Slowik

Western North American Naturalist

Capture data differed at woodrat houses associated with selected microhabitats in a chaparral-oak woodland site in the foothills of northwestern California. Mean trapping success was significantly higher at houses located under dense tree canopy (and in low scrub cover) compared with houses in high scrub cover (and under less tree canopy), as was trapping success at houses found in non-edge versus edge habitat. Woodrats trapped at houses under dense canopy also were significantly heavier than those captured in high scrub cover; however, mean body masses at edge- and non-edge houses were similar. Broadly, our results mirror existing research but indicate …

Food Habits Of Coyotes, Gray Foxes, And Bobcats In A Coastal Southern California Urban Landscape, Rachel N. Larson, Dana J. Morin, Izabela A. Wierzbowska, Kevin R. Crooks

Western North American Naturalist

Many carnivores are sensitive to habitat fragmentation, and the capacity to shift diets may improve their ability to persist in urban areas. We collected and identified contents of a total of 119 scats from coyotes (Canis latrans), 58 scats from gray foxes (Urocyon cinereoargenteus), and 31 scats from bobcats (Lynx rufus) within habitat fragments ofvarying size in the San Diego area in coastal southern California. Coyote diet was generalist, composed of mostly mammals but also anthropogenic items, fruit and seeds, birds, and invertebrates. Dietary breadth of coyotes was similar in small urban habitat fragments and …

Institutional Factors Influencing African-American Male Involvement In Undergraduate Student Organizations, John Mark Davenport

Theses and Dissertations

Students attending colleges and universities who have purposeful opportunities to interact with peers and faculty about educational matters and who are challenged with consistent encouragement report higher levels of satisfaction with their collegiate experience and have higher persistence rates than students who do not receive these opportunities (Kuh et al., 1991; Pascarella & Terenzini, 1991; Schroeder & Mable, 1994). In higher education, African-American males are neither retained from admission through graduation at a rate comparable to majority students nor African-American women (AASCU, 1988; ACE, 2008; Harper, 2012). In this study I set out to determine which institutional factors influence African-American …

Lack Of Resistance Of Plasmodium Falciparum To Dihydroartemisinin In Uganda Based On Parasitogolgical And Molecular Assays, Roland A. Cooper, Melissa D. Conrad, Quentin D. Watson, Stephanie J. Huezo, Harriet Ninsiima, Patrick Tumwebaze, Samuel L. Nsobya, Philip J. Rosenthal

Collected Faculty Scholarship

• Artemisinin-­‐based combination therapy is now standard treatment for falciparum malaria. However, this regimen is threatened by resistance to artemisinins, manifest as delayed clearance of parasitemia after therapy, in southeast Asia.

• Artemisinin resistance in southeast Asia is associated with increased parasitemias in culture, compared to those in sensi0ve parasites, 72 hours a=er a 6 hour pulse with 700 nM dihydroartemisinin (DHA), and with propeller domain polymorphisms in the Plasmodium falciparum kelch (K13; PF3D7_1343700) gene

• Given that artemether/lumefantrine has been adopted as standard therapy for malaria within the last decade in Uganda, we characterized artemisinin sensiBvity in fresh P. falciparum isolates from …

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Champions Of Healthcare Awards 2015 Program, Pcom Office Of Diversity And Community Relations

Diversity and Inclusion

Invitation and Program for Georgia Campus' 2015 Champions of Healthcare Awards.

Keynote Speaker: Barbara Ross-Lee, DO, FACOFP, New York Institute of Technology Vice President for Health Sciences and Medical Affairs

Awardees: Colleen D. Heer; Jeffrey K. Seiple, MBA, LFD, LE; Srujana Rayalam, BVSc, MVSc, PHD; Shu Zhu, MD, PhD; Mark D. Darrow, MD FACP; Nathan M. Polite, DO; Jennifer L. Gooch, PhD; Brittany Melvin (MS/Biomed ’16); Carly Duncan (PharmD ’16); Thuy Le (DO ‘17); Senator Renee Unterman; Hannah Southerland (PharmD ’19)

The Potential For A Blood Test For Scabies, Larry G. Arlian, Hermann Feldmeier, Majorie S. Morgan

Biological Sciences Faculty Publications

Scabies, caused by the mite S. scabiei that burrows in the skin of humans, is a contagious skin disease that affects millions of people worldwide. It is a significant public health burden in economically disadvantaged populations, and outbreaks are common in nursing homes, daycare facilities, schools and workplaces in developed countries. It causes significant morbidity, and in chronic cases, associated bacterial infections can lead to renal and cardiac diseases. Scabies is very difficult to diagnose by the usual skin scrape test, and a presumptive diagnosis is often made based on clinical signs such as rash and itch that can …

Quaker Campus, October 22, 2015 (Vol. 102, Issue 7), Whittier College

Quaker Campus

No abstract provided.

The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence By Enhancing Resistance To Neutrophil Extracellular Traps, Mark J. Lee, Hong Liu, Bridget M. Barker, Brendan D. Snarr, Fabrice M. Gravelat, Qusai Al Abdallah, Christina Gavino, Shane R. Baistrocchi, Hanna Ostapska, Tianli Xiao, Benjamin Ralph, Norma V. Solis, Melanie Lehoux, Stefanie D. Baptista, Arsa Thammahong

Dartmouth Scholarship

Of the over 250 Aspergillus species, Aspergillus fumigatus accounts for up to 80% of invasive human infections. A. fumigatus produces galactosaminogalactan (GAG), an exopolysaccharide composed of galactose and N-acetyl-galactosamine (GalNAc) that mediates adherence and is required for full virulence. Less pathogenic Aspergillus species were found to produce GAG with a lower GalNAc content than A. fumigatus and expressed minimal amounts of cell wall-bound GAG. Increasing the GalNAc content of GAG of the minimally pathogenic A. nidulans, either through overexpression of the A. nidulans epimerase UgeB or by heterologous expression of the A. fumigatus epimerase …

The Effects Of Guided Imagery On Patients Being Weaned From Mechanical Ventilation, Leeanna Spiva, Patricia L. Hart, Erin Gallagher, Frank Mcvay

Faculty Articles

The study purpose was to assess the effects of guided imagery on sedation levels, sedative and analgesic volume consumption, and physiological responses of patients being weaned from mechanical ventilation. Forty-two patients were selected from two community acute care hospitals. One hospital served as the comparison group and provided routine care (no intervention) while the other hospital provided the guided imagery intervention. The intervention included two sessions, each lasting 60 minutes, offered during morning weaning trials from mechanical ventilation. Measurements were recorded in groups at baseline and 30- and 60-minute intervals and included vital signs and Richmond Agitation-Sedation Scale (RASS) score. …

Spartan Daily, October 21, 2015, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 145, Issue 25

The Anchor, Volume 129.07: October 21, 2015, Hope College

The Anchor: 2015

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.

Gi Bleed With Pancytopenia - A Rare Case Of Aml Subtype Acute Panmyelosis With Mylefibrosis (Apmf), Dhwani Pandya Md, Philip Dunn Do, Stacey Smith Md, Facp

Department of Medicine

No abstract provided.

Loss Of Glycosaminoglycan Receptor Binding After Mosquito Cell Passage Reduces Chikungunya Virus Infectivity, Amber M. Paul, Dhiraj Acharya, John F. Anderson, Faqing Huang, Fengwei Bai

Publications

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that can cause fever and chronic arthritis in humans. CHIKV that is generated in mosquito or mammalian cells differs in glycosylation patterns of viral proteins, which may affect its replication and virulence. Herein, we compare replication, pathogenicity, and receptor binding of CHIKV generated in Vero cells (mammal) or C6/36 cells (mosquito) through a single passage. We demonstrate that mosquito cell derived CHIKV (CHIKVmos) has slower replication than mammalian cell derived CHIKV (CHIKVvero), when tested in both human and murine cell lines. Consistent with this, CHIKVmos infection in both cell lines produce less cytopathic …

Odorant Receptor-Based Discovery Of Natural Repellents Of Human Lice, Julien Pelletier, Pingxi Xu, Kyong-Sup Yoon, John M. Clark, Walter S. Leal

SIUE Faculty Research, Scholarship, and Creative Activity

The body louse, Pediculus humanus humanus, is an obligate blood-feeding ectoparasite and an important insect vector that mediates the transmission of diseases to humans. The analysis of the body louse genome revealed a drastic reduction of the chemosensory gene repertoires when compared to other insects, suggesting specific olfactory adaptations to host specialization and permanent parasitic lifestyle. Here, we present for the first time functional evidence for the role of odorant receptors (ORs) in this insect, with the objective to gain insight into the chemical ecology of this vector. We identified seven putative full-length ORs, in addition to the odorant receptor …

Workplace Safety Concerns Among Co-Workers Of Responder Returning From Ebola-Affected Country, Benjamin P. Chan, Elizabeth R. Daly, Elizabeth A. Talbot

Dartmouth Scholarship

We surveyed public health co-workers regarding attitudes toward a physician who returned to New Hampshire after volunteering in the West African Ebola outbreak. An unexpectedly large (18.0%) proportion of staff expressed discomfort with the Ebola responder returning to work. Employers should take proactive steps to address employee fears and concerns.

My News

My News (2014-2020)

• Garden of the Coastal Plain announces name change to Botanic Garden to reflect plans for growth
• School of Nursing Memorial Garden honors, remembers nursing students
• Herty Center wins critical role in Department of Energy National Project
• Campus Halloween events begin this week
• International Fashion Show Hits the Runway this October

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Georgia Southern University dedicates School of Nursing Memorial Garden
• Georgia Southern conference designed to inspire H.O.P.E. in HIV/AIDS care to rural communities

2015-October-16-Professor Receives Federal Grant To Study Protein To Treat Cirrhosis Johnson City, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.