Digital Commons Network^™

Quotable: Fran Ligler '72, Fran Ligler '72

Furman Magazine

No abstract provided.

Class Notes, Furman University

Furman Magazine

No abstract provided.

Coping With A New "Yellow Peril": Japanese Immigration, The Gentleman's Agreement, And The Coming Of World War Ii, Paul Finkelman

West Virginia Law Review

No abstract provided.

Influence And Characterization Of Microbial Contaminants Associated With The Fda Bam Method Used To Detect Listeria Monocytogenes From Romaine Lettuce, Christopher E. Bach

Open Access Theses

Over the past few decades in the US, fresh produce commodities have become increasingly prevalent vehicles for the attribution of foodborne illness. Recent outbreaks of the bacterial foodborne pathogen Listeria monocytogenes linked to fresh produce highlight this immediate issue facing food safety. The most widely used method to screen L. monocytogenes from food matrices in the US is the Bacteriological Analytical Manual (BAM) developed by the Food and Drug Administration (FDA). Detection of this pathogen from all foods is primarily accomplished by using four FDA approved Listeria selective media: Oxford (OXA), modified Oxford (MOX), Lithium chloride-phenylethanol-moxalactam fortified with esculin and …

Baylisascaris Spp. In Non-Raccoon Procyonid Hosts And Assessment Of Potential Risk Of Human Exposure, Max Carlin Parkanzky

Open Access Theses

Baylisascaris procyonis (Bp) is a large roundworm of the common raccoon (Procyon lotor) which serves as the definitive host. Bp is an important cause of clinical larva migrans, including severe neurological disease, across numerous taxa including humans. Other procyonids, as well as occasionally dogs, can act as definitive hosts for this or other Baylisascaris spp. Many of these animals are becoming more common as household pets, posing a risk to people who come in contact with these animals. We have investigated whether patent Baylisascaris spp. infection exists in captive non-raccoon procyonids and if humans who contact these animals …

Discrete Epidemic Models With Arbitrarily Distributed Disease Stages, Nancy Hernandez Ceron

Open Access Dissertations

The use of discrete-time models (or discrete models) in the field of mathematical epidemiology has been limited while continuous-time models (or continuous models) are often times preferred, particularly because disease dynamics do occur continuously in time and more mathematical tools are available for model analysis. How- ever, discrete models are not only more tractable and easier to understand, but also more directly related to data, particularly when the disease stage distributions are arbitrarily distributed (e.g., when the data cannot be fitted by distributions from a parametric family). Under these circumstances continuous models usually lead to complex system of integral equations. …

Investigating Synergy: Mathematical Models For The Coupled Dynamics Of Hiv And Hsv-2 And Other Endemic Diseases, Christina M Alvey

Open Access Dissertations

This dissertation presents epidemiological models that investigate synergy: synergy between HIV and HSV-2 or between humans and mosquitoes in a malaria study. Each of the three coupled disease models addresses different epidemiological questions with regard to gender or disease structure in the context of sexually-transmitted diseases (STDs), while the malaria model focuses on age-structure of the human population. ^ Mounting evidence indicates that HSV-2 infection may increase susceptibility to HIV infection and that co-infection may increase infectiousness. Accordingly, antiviral treatment of people with HSV-2 may mitigate the incidence of HIV in populations where both pathogens occur. To better understand the …

Modeling Person-To-Person Contaminant Transport In Enclosed Environments, Chun Chen

Open Access Dissertations

It is essential to predict person-to-person contaminant transport in enclosed environments to improve air distribution design and reduce the infection risk from airborne infectious diseases. This study aims to improve and accelerate the simulation of person-to-person contaminant transport in enclosed environments. ^ This investigation first conducted experimental measurements of person-to-person contaminant transport in an office mockup and the first-class cabin of a functional MD-82 aircraft. The experimental data of steady-state airflow, temperature, and gas contaminant concentration fields obtained in the office were used to validate the steady-state computational fluid dynamics (CFD) models. In the aircraft cabin, the transient particle concentrations …

Macrophage Cox-2 As A Target For Imaging And Therapy Of Inflammatory Diseases Using Theranostic Nanoemulsions, Sravan Kumar Patel

Electronic Theses and Dissertations

Personalized medicine can be an approach to address the unsatisfactory treatment outcomes in inflammatory conditions such as cancer, arthritis, and cardiovascular diseases. A common feature of chronic diseases is the infiltration of pro-inflammatory macrophages at the disease loci. Infiltrating macrophages have been previously utilized for disease diagnosis. These features suggest that macrophages can be broadly applicable targets for simultaneous therapy and diagnosis. Cyclooxygenase-2 (COX-2), an enzyme involved in the biosynthesis of a lipid inflammatory mediator, prostaglandin E2 (PGE2), is over expressed in macrophages infiltrating the pathological site. Inhibition of PGE2 leads to reduced inflammation, pain and macrophage infiltration. To utilize …

Sociodemographic And Behavioral Correlates Of Anogenital Warts And Human Papillomavirus-Related Knowledge Among Men Who Have Sex With Men And Transwomen In Lima, Peru, Brandon Brown, Emmi Monsour, Jeffrey D. Klausner, Jerome T. Galea

Social Work Faculty Publications

Background Human papilloma virus (HPV) is the most common sexually transmitted infection (STI) globally, with a high burden of anogenital warts (AGW) among men who have sex with men (MSM) and transwomen (TW).

Methods Six-hundred HIV negative MSM and TW (300 with AGW, 300 without) were recruited for a prospective cohort study to examine HPV outcomes and HPV vaccine knowledge. Participants completed a self-administered online questionnaire. Logistic regression was used to assess the association between sociodemographic and behavioral characteristics with HPV vaccine knowledge.

Results The average participant age was 25.5 years. Most (67%) were single and 41.2% self-reported STI symptoms. …

The Children’S Health Project: Creation Of A Community Model For Increasing Vaccination Rates In Children, Brooke E. Long

Honors Projects

No abstract provided.

Growing A Healthy Future, Spring 2015

Institute of Agriculture and Natural Resources: Institute Publications

Combating obesity; Unique virus research; Building the campus; Women in Agriculture; Marketing ups and downs ;1roadband Reaching Out; Weathering a new major; Birds of different feathers; Growing communities; Farm bill expertise; Giving back

Sexual Health Risk Behaviors Among Older Men Who Have Sex With Men: Implications For Interventions, Franco Dispenza, Brian J. Dew, Alexander K. Tatum, Edison C. M. Wolf

Adultspan Journal

No abstract provided.

Medication-Assisted Treatment For Pregnant Women: A Systematic Review Of The Evidence And Implications For Social Work Practice, Amber M. Holbrook, Viba H. Nguyen

Social Work (Graduate) Faculty Publications

Evidence-based practice with pregnant clients who are opioiddependent can be especially challenging because pregnant women are rarely included in clinical trials. The paper synthesizes systematic reviews on the outcomes of medication-assisted treatment for opioid dependent pregnant women and compares the effectiveness of methadone and buprenorphine. We explore evidence on maternal and neonatal outcomes, the safety of breastfeeding, and discuss the implications for social work practice. Searches were conducted in 6 databases. Ten reviews met the inclusion criteria. Results suggest medication-assisted treatment with either methadone or buprenorphine are equally effective in reducing maternal substance use, although methadone may offer slightly higher …

Development Of A T7 Phage Display Library To Detect Sarcoidosis And Tuberculosis By A Panel Of Novel Antigens, Harvinder Talwar, Rita Rosati, Jia Li, Dana Kissner, Samiran Ghosh, Félix Fernández-Madrid, Lobelia Samavati

Public Health Sciences Articles

Sarcoidosis is a granulomatous inflammatory disease, diagnosed through tissue biopsy of involved organs in the absence of other causes such as tuberculosis (TB). No specific serologic test is available to diagnose and differentiate sarcoidosis from TB. Using a high throughput method, we developed a T7 phage display cDNA library derived from mRNA isolated from bronchoalveolar lavage (BAL) cells and leukocytes of sarcoidosis patients. This complex cDNA library was biopanned to obtain 1152 potential sarcoidosis antigens and a microarray was constructed to immunoscreen two different sets of sera from healthy controls and sarcoidosis. Meta-analysis identified 259 discriminating sarcoidosis antigens, and multivariate …

A Comparison Of The Genetic Diversity Of The Class Ii Major Histocompatibility Complex In Ex Situ And In Situ Populations Of African Penguins (Spheniscus Demersus), Emily Willmer

Undergraduate Honors Thesis Projects

As an endangered species, the African penguin (Spheniscus demersus) is at risk of becoming extinct in the wild due to destruction of their coastal habitat and reduction in food availability. The development of a genetically diverse and healthy captive population is important in helping to conserve the species. The goal of this project was to determine the genetic diversity of the class II major histocompatibility complex (MHC) of a wild population of African penguins and compare it to the diversity of the captive population at Mystic Aquarium in Mystic, Connecticut that has previously been studied. We found that …

Nsu Sharks Rx - Spring 2015, College Of Pharmacy

NSU Sharks Rx

No abstract provided.

Yale Medicine : Alumni Bulletin Of The School Of Medicine, Spring 2015, Yale University. School Of Medicine

Yale Medicine Magazine - alumni bulletin and magazine

This is the Spring 2015 issue of Yale Medicine: alumni bulletin of the School of Medicine, v. 49, no. 2. Prepared in cooperation with the alumni and development offices at the School of Medicine. Earlier volumes are called Yale School of Medicine alumni bulletins, dating from v.1 (1953) through v.13 (1965).

Times Of Polio: The 1956 Epidemic In Buenos Aires, Amy Dipierro , '15

Senior Theses, Projects, and Awards

In 1956, Buenos Aires experienced one of the worst polio epidemics ever recorded in the city. The epidemic grabbed local headlines and inspired international aid campaigns, shaped and was shaped by public health policies and changed the course of countless patients' lives. By flipping through the pages of popular newspapers and film reels, this thesis tries to recreate the collective experience of polio in this time and place; by peeking into patient records, it asks whether historians can also recreate the individual experiences of polio sufferers through the eyes of their caretakers, too. Along the way, this story explores the …

Columns Spring 2015, Southern Adventist University

Alumni Newsletter

Features the article " Beyond Books". Student research projects reflect academic excellence on campus, a major component of the Southern Experience.

The Sociological Eye 2015, Loyola Marymount University, Sociology Department

The Sociological Eye Student Journal

Faculty Advisor: Dr. Nadia Kim & Dr. Rebecca Sager

Co-Editors: Elizabeth Ashton Harris & Monica Zamora

Nursing And Midwifery Links [April 2015 Issue], At The University Of Technology Sydney In Australia. Who Collaborating Centers For Nursing And Midwifery Development. Global Network. Secretariat

Nursing and Midwifery Links (LINKS)

The document attached to this record is the first Global Network Links Magazine produced by the newly elected [at time of publication] Secretariat of the Global Network of WHO Collaborating Centres for Nursing and Midwifery at the University of Technology Sydney in Australia. It highlights the ongoing work of Network members.

Promoting Adult Pertussis Vaccination In The Workplace, Jennifer Bainum, Karlen Beth Luthy, Renea L. Beckstrand, Janelle L. B. Macintosh, Lacey M. Eden

Student Works

Vaccines are an important disease prevention strategy among individuals of all age groups. Despite the success of vaccinations in preventing communicable diseases, adults, in particular, often have sub-optimal vaccination rates. Consequently, some vaccine-preventable diseases, such as pertussis, are still on the rise in the United States despite the availability of the Tdap vaccine. As most adults can be found in the workplace, occupational health and environmental health nurses (OHEHNs) are in a unique role to encourage employers to promote adequate Tdap vaccination among their employees. As specific resources regarding Tdap vaccination are lacking, the Pertussis Prevention Toolkit was developed to …

Full Page Ads

Against the Grain

No abstract provided.

Hydatid Cyst Of Thoracic Spine: A Rare Cause Of Paraplegia, Rahul Soangra, Mool Chand Soangra

Physical Therapy Faculty Articles and Research

Primary spinal hydatid cysts are uncommon and extradural involvement is rare. We report an unusual case of Paraplegia due to hydatid disease of primary site of infection extra spinal muscles in thoracic region from T5 to T8 level extending into a daughter cyst at T9 level, is main cause of acute Paraplegia. Magnetic resonance imaging (MRI) showed an extradural round cystic lesion in the spinal canal filling the posterior and left postero-lateral expect at T9 level, markedly compressing the cord. The cyst was removed after laminectomy and opening of the dural sac, with excision of extraspinal mass in left paravertebral …

Aggregatibacter Actinomycetemcomitans Cytolethal Distending Toxin Activates The Nlrp3 Inflammasome In Human Macrophages Leading To The Release Of Pro-Inflammatory Cytokines, Bruce J. Shenker, David M. Ojcius, Lisa P. Walker, Ali Zekavat, Monika Damek Scuron, Kathleen Boesze-Battaglia

All Dugoni School of Dentistry Faculty Articles

The cytolethal distending toxin (Cdt) is produced from a number of bacteria capable of causing infection and inflammatory disease. Our previous studies with Actinobacillus actinomycetemcomitans Cdt demonstrate not only that the active toxin subunit functions as a phosphatidylinositol-3,4,5-triphosphate (PIP3) phosphatase but also that macrophages exposed to the toxin were stimulated to produce proinflammatory cytokines. We now demonstrate that the Cdt-induced proinflammatory response involves the activation of the NLRP3 inflammasome. Specific inhibitors and short hairpin RNA (shRNA) were employed to demonstrate requirements for NLRP3 and ASC as well as caspase-1. Furthermore, Cdt-mediated inflammasome activation is dependent upon upstream signals, including reactive …

The U.S. Food Safety Modernization Act: Implications In Transnational Governance Of Food Safety, Food System Sustainability, And The Tension With Free Trade, Neal Fortin

Duke Environmental Law & Policy Forum

No abstract provided.

Immunization Policies For Employees Of Childcare Facilities Within The North Central Health District Of Georgia, Paula Kamara, Brad Lian, Jimmie H. Smith, Judy Mcchargue

Journal of the Georgia Public Health Association

Background: Since the early 1980s, vaccinations have generally been required for children in licensed daycare and school settings. In these settings, vaccinations have reduced disease rates. Adults occupy these settings as well, and ensuring they are vaccinated should also reduce the potential for disease and disease transmission. Yet, there are few vaccination requirements for adults employed at daycare facilities, although such requirements have been recommended (CDC Adult immunization schedule, 2015; ACIP General Recommendations, 2011). The objective of this study was to examine current vaccination policies among childcare facilities within Georgia’s North Central Health District (District 5-2) and the climate for …

Ursinus Magazine, Spring 2015, Wendy Greenberg, Kathryn Campbell, Ellen Labrecque, Jennifer Meininger Wolfe, Terry Winegar, Rachel Jessica Daniel, Jacqueline Yost Limongelli

Ursinus Magazine, 1995–Present

Setting a high standard: Presidential search is underway • Pfahler rocks • New website launches • Lost & found • Professor of the year • 2015 externships • Office space: Jimena Talavera 2012 • 2014 Homecoming • Mullen named Maxwell Football Club's Collegiate Coach of the Year • Rebecca E. Kohn named Associate Dean • A boost for UC Bikeshare • Reaching out, warming up • Battling Ebola • Wordsmith • Berman Museum: Museum Studies • The ties that bind • Greek life remains strong on campus • Wings to go • One goal: That's all it takes • Class …

Sexually Transmitted Disease Education And Effects On Condom Use In College Students, Patricia Alvarez

Doctoral Projects

In the United States, nearly 50% of the sexually transmitted diseases (STDs) reported each year occur in adolescents and young adults ages 15-24. An IRB approved, exploratory mix method research study was conducted in a California Community College to investigate participants' opinions on STD education tools, effectiveness, and to rank preferred instructional methods used in 51h-12'h grades. One hundred and thirteen students participated and reported use of variety of educational tools with the lecture technique selected by almost 80% surveyed. Demonstration of condom application had highest percent ranked as number one for the preferred educational tool; yet had the least …