Digital Commons Network^™

Whom Do You Trust? Doubt And Conspiracy Theories In The 2009 Influenza Pandemic, Shawn C. Smallman Ph.D.

Journal of International and Global Studies

The 2009 pandemic of H1N1 influenza led people around the globe to create narratives about the epidemic defined by the question of trust; these narratives ranged from true conspiracy theories to simply accounts in which mistrust and betrayal formed a motif. In particular, most of these narratives reflected a fear of capitalism and globalization, although in specific regions, other issues—such as religion—played a more central role. These stories were not unique to the H1N1 pandemic but rather have appeared with every contemporary outbreak of infectious disease. This paper will examine conspiracy theories and moral panics related to the H1N1 pandemic …

Ua77/1 Wku Spirit, Wku Alumni Relations

WKU Administration Documents

WKU's alumni magazine. Contents:

• Jimmy Feix 1931-2014
• Ransdell, Gary. Letter from the President
• Thompson Complex – North Wing Razed
• WKU Yearbook Wins Pacemaker Award – Talisman
• Neale Chumbler Named Dean of College of Health & Human Services
• Six Gatton Academy of Mathematics & Science Students Semifinalists in 2014 Siemans Competition
• WKU Among 30 Most Beautiful College Campuses in the South
• Don Dizney Receives Honorary Doctorate for Public Service
• WKU Named to Military Friendly Schools List for 6^th Straight Year
• WKU Listed in Open Doors Report for Study Abroad Participation
• Six WKU Students Honored by Gilman Scholarship Program
• WKU Graduate …

Analyses Of Nutrient And E. Coli Contamination Within The Otter Creek Watershed, Madison County, Ky, Nathaniel C. Crockett

Geosciences Undergraduate Theses

The Otter Creek watershed exhibits dissolved nutrient (ammonium, NH⁴¹⁺; nitrate, NO₃^1-; phosphate, PO₄^3-) and Escherichia coli contamination that compromises its water quality. The watershed covers a substantial portion of Madison County (~168 km²) and consists of Lake Reba, Dreaming Creek, and east and west forks, all of which enter the trunk of Otter Creek before flowing into the Kentucky River. Suspected contaminate sources include leaky sewage system pipes, runoff from pasture land, and septic system leachate. We collected 330 water samples on three occasions during summer 2014 to determine the …

Accuracy Of Highly Sexually Active Gay And Bisexual Men’S Predictions Of Their Daily Likelihood Of Anal Sex And Its Relevance For Intermittent Event-Driven Hiv Pre-Exposure Prophylaxis, Jeffrey T. Parsons, H. Jonathon Rendina, Christian Grov, Ana Ventuneac, Brian Mustanski

Publications and Research

Objective: We sought to examine highly sexually active gay and bisexual men’s accuracy in predicting their sexual behavior for the purposes of informing future research on intermittent, event-driven HIV Pre-Exposure Prophylaxis (PrEP).

Design: For 30 days, 92 HIV-negative men completed a daily survey about their sexual behavior (n = 1,688 days of data) and indicated their likelihood of having anal sex with a casual male partner the following day.

Method: We utilized multilevel modeling to analyze the association between self-reported likelihood of and subsequent engagement in anal sex.

Results: We found a linear association between men’s reported likelihood …

Accounting For Sick Days: A Scalar Approach To Health And Disease At Deir El-Medina, Anne Austin

Educator Preparation & Leadership Faculty Works

No abstract provided.

Investigation Of Dual Stage Acridones As A Potent Malaria Treatment, Stephanie Huezo

Dissertations, Masters Theses, Capstones, and Culminating Projects

The need for potent antimalarials to prevent the emergence of drug resistant Plasmodium falciparum is urgent. Discovery of novel acridone chemotypes have shown promise for a new antimalarial drug treatment. Presently, two acridone chemotypes have intrinsic antimalarial potency against chloroquine sensitive and multidrug resistant parasites. Acridones lacking an N10 side chain are known as chemotype I acridones, whereas, chemotype II acridones are defined as having an alkyl side chain at the same position. The N10 substitution of chemotype II acridones is thought to target heme and inhibit hemozoin formation within the parasite’s digestive vacuole, and is known to provide synergistic …

Ulaanbaatar’S Ger District Issues: Changes And Attitudes, David Engel

Independent Study Project (ISP) Collection

Several of Ulaanbaatar’s current issues are directly related to Ulaanbaatar’s sprawling Ger District. The Ger District is home to approximately 736,000 residents, 61% of Ulaanbaatar’s population (Galimbyek, 2015). The significant growth in Ulaanbaatar is shown by its 52.8% of residents who were born outside of the city, the majority of migrants moving into the Ger District due to a lack of housing. (Chilkhaasuren & Baasankhuu, 2012). The development of Ulaanbaatar has not kept up with the rapid growth leading to inadequate infrastructure in much of the Ger District. In turn, inadequate infrastructure has lead to high pollution levels, negatively affecting …

Wsu Research News, Spring 2015, Office Of Research And Sponsored Programs, Wright State University

WSU Research News

An eighteen page newsletter of the WSU Research News. The WSU Research News was published monthly beginning in June of 1968 and issued by the Office of Research Development. This newsletter was created to provide information to the WSU faculty about the availability of outside funds for research and educational programs, new developments that may affect availability of funds, and general information on research and educational activities at Wright State University.

Is Green Tea The Panacea We’Ve Been Searching For? A Review Of The Scientific Literature On Green Tea And Human Health, Eleanor L. Axson

Senior Honors Projects

There are many claims surrounding the health benefits of consuming green tea, some of which involve its use in the treatment of medical conditions as wide ranging as cancer, diabetes, and neuro-degenerative disorders. The desire for the use of non-toxic and natural drugs to treat various diseases makes any health-benefitting claims about green tea and its components important to investigate for their potential public health benefits. I conducted a critical review of the research literature on green tea and its effects on human health and synthesized the results. There is convincing epidemiological evidence pointing to the health benefits derived from …

Alkaloid-Based Chemical Defenses In The Brazilian Poison Frog Melanophryniscus Simplex Inhibit Mycobacterial Growth, Megan A. Boyk

Senior Honors Projects

This study investigated the antimycobacterial properties of M. simplex alkaloids from geographically isolated populations against two species of mycobacteria, M. smegmatis, a soil-dwelling species, and M. phlei, a saprophytic species (Berney et al. 2014; Egamberdieva 2011). Both of these species are fast-growing, commonly found in the environment, and typically nonpathogenic in healthy animals (Balazova et al. 2014, Berney et al. 2014, Egamberdieva 2011). Both M. smegmatis and M. phlei are commonly used as model strains for the study of antimycobacterial agents (Zhang et al. 2014, Bruce-Micah et al. 2009). Optical density and colony-forming unit assays were used to evaluate …

Utilization Of A Real-Time Pcr Assay For Diagnosis Of Babesia Microti Infection In Clinical Practice, Guiqing Wang, Gary P. Wormser, Jian Zhuge, Patrick Villafuerte, Dawn Ip, Christine Zeren, John T. Fallon

NYMC Faculty Publications

Babesiosis is an emerging tick-borne disease mainly caused Babesia microti, a protozoan that infects erythrocytes. Microscopic examination of blood smears is the current gold standard for detection of Babesia infection, but this diagnostic test has several limitations. We developed and assessed the clinical utilization of a multiplex real-time PCR assay targeting the 18S rRNA gene of B. microti and the human gapdh gene. The limit of detection of this PCR assay was approximately 1-3parasites/μl of blood. The assay showed a diagnostic sensitivity and probable specificity of 100% based on testing 145 retrospective and 185 prospective blood specimens from controls and …

Viral Bimolecular Fluorescence Complementation: A Novel Tool To Study Intracellular Vesicular Trafficking Pathways, Brennan S Dirk, Rajesh Abraham Jacob, Aaron L Johnson, Emily N Pawlak, P Craig Cavanagh, Logan Van Nynatten, S M Mansour Haeryfar, Jimmy D. Dikeakos

Microbiology & Immunology Publications

The Human Immunodeficiency Virus type 1 (HIV-1) accessory protein Nef interacts with a multitude of cellular proteins, manipulating the host membrane trafficking machinery to evade immune surveillance. Nef interactions have been analyzed using various in vitro assays, co-immunoprecipitation studies, and more recently mass spectrometry. However, these methods do not evaluate Nef interactions in the context of viral infection nor do they define the sub-cellular location of these interactions. In this report, we describe a novel bimolecular fluorescence complementation (BiFC) lentiviral expression tool, termed viral BiFC, to study Nef interactions with host cellular proteins in the context of viral infection. Using …

Clinical Challenges In Isolation Care, Elizabeth L. Beam, Shawn G. Gibbs, Angela L. Hewlett, Peter C. Iwen, Suzanne L. Nuss, Philip W. Smith

Journal Articles: College of Nursing

OVERVIEW: In 2014, the authors published the results of a study investigating nurses' use of personal protective equipment (PPE) in the care of a live simulated patient requiring contact and airborne precautions. The 24 participants were video-recorded as they donned and doffed PPE. Variations in practices that had the potential to cause contamination were noted. In this article, the authors comment on those variations, analyzing each element of proper PPE protocols and examining why the behaviors are a safety concern for the nurse and a potential risk for disease transmission in the hospital or other clinical area. The authors note …

Math Colloquium Many-Particle Dynamics Via Differential Inclusions, April 8, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

True Durability: Hiv Virologic Suppression In An Urban Clinic And Implications For Timing Of Intensive Adherence Efforts And Viral Load Monitoring, Debra A. Benator, Angelo Elmi, Manuel D. Rodriguez, Howard B. Gale, Virginia L. Kan, Heather J. Hoffman, Susan Tramazzo, Karen Hall, Angela Mcknight, Leah Squires

Medicine Faculty Publications

Although the majority of HIV-infected patients who begin potent antiretroviral therapy should expect long-term virologic suppression, the realities in practice are less certain. Durability of viral suppression was examined to define the best timing of targeted adherence strategies and intensive viral load monitoring in an urban clinic population with multiple challenges to ART adherence. We examined the risk of viral rebound for patients who achieved two consecutive viral loads lower than the lower limit of quantification (LLOQ) within 390 days. For 791 patients with two viral loads below the LLOQ, viral rebound >LLOQ from the first viral load was 36.9 …

Medicine + Health, Spring 2015, George Washington University, School Of Medicine And Health Sciences, Office Of Communications And Marketing

Medicine + Health Magazine

No abstract provided.

True Durability: Hiv Virologic Suppression In An Urban Clinic And Implications For Timing Of Intensive Adherence Efforts And Viral Load Monitoring., Debra A Benator, Angelo Elmi, Manuel D Rodriguez, Howard B Gale, Virginia L. Kan, Heather J. Hoffman, Susan Tramazzo, Karen Hall, Angela Mcknight, Leah Squires

Medicine Faculty Publications

Although the majority of HIV-infected patients who begin potent antiretroviral therapy should expect long-term virologic suppression, the realities in practice are less certain. Durability of viral suppression was examined to define the best timing of targeted adherence strategies and intensive viral load monitoring in an urban clinic population with multiple challenges to ART adherence. We examined the risk of viral rebound for patients who achieved two consecutive viral loads lower than the lower limit of quantification (LLOQ) within 390 days. For 791 patients with two viral loads below the LLOQ, viral rebound >LLOQ from the first viral load was 36.9 …

The Predictive Value Of Current Haemoglobin Levels For Incident Tuberculosis And/Or Mortality During Long-Term Antiretroviral Therapy In South Africa: A Cohort Study, Andrew D. Kerkhoff, Robin Wood, Frank G. Cobelens, Ankur Gupta-Wright, Linda-Gail Bekker, Stephen D. Lawn

Medicine Faculty Publications

Background

Low haemoglobin concentrations may be predictive of incident tuberculosis (TB) and death in HIV-infected patients receiving antiretroviral therapy (ART), but data are limited and inconsistent. We examined these relationships retrospectively in a long-term South African ART cohort with multiple time-updated haemoglobin measurements.

Methods

Prospectively collected clinical data on patients receiving ART for up to 8 years in a community-based cohort were analysed. Time-updated haemoglobin concentrations, CD4 counts and HIV viral loads were recorded, and TB diagnoses and deaths from all causes were ascertained. Anaemia severity was classified using World Health Organization criteria. TB incidence and mortality rates were calculated …

Managing For Social Change: Improving Labor Department Performance In A Partisan Era, Seth D. Harris

West Virginia Law Review

No abstract provided.

T&C Magazine Issue 08 - Spring 2015, T&C Media

T&C Magazine

Articles include: Best of Both Worlds // Powering Up Against the Odds // Integrated Studies // Otterbein's Mark // Alumni with Cool Careers // Resilience, Leadership, and Generosity // The Islam Misconception // Violet's Tale // In the Studio // Uncommon Knowledge // Where in the World Are You From?

Speech-Conditioned Funding And The First Amendment: New Standard, Old Doctrine, Little Impact, Heather Blakeman

Northwestern Journal of Human Rights

No abstract provided.

Akhuwat Issue No. 97, Aga Khan University

AKHUWAT Newsletters

• Aga Khan University graduates to have a “Multiplier Effect” in civil society
• AKU marks 15th anniversary in East Africa
• Convocations
• Moving Towards a New Learning Agenda AKU Teaching Champions
• First world-class operating rooms inaugurated
• Mr. Shekar Iyer, Chief Operating Officer, AKU-EA
• The Spirit of Volunteerism Working for a cause, not for applause
• Contribution of Dr Muhammad Memon
• Contribution of Dr. Keith Cash
• Presentation of Ten Years Service Awards
• HIMS Journey to Excellence
• Open Day at AKU
• Advance Nurse Practitioner programme of AKUH
• Top 10 Leadership Tips for First-time Managers
• Workshops and Events
• New Private Wing (NPW)
• 26th Annual IHI National …

Overconsumption Of Antibiotics, Haley J. Morrill, L. Laplante

Pharmacy Practice and Clinical Research Faculty Publications

We applaud Thomas Van Boeckel and colleagues¹ for their large analysis of antibiotic consumption in 71 countries. A 36% increase in use of antibiotics worldwide, 76% of which was in Brazil, Russia, India, China, and South Africa, is a concerning finding. In Europe and the USA, practitioners are increasingly aware of the importance of infection control and antimicrobial stewardship. However, 50% of antimicrobials, irrespective of setting, are used inappropriately.^2,3 We agree that most increases in global antibiotic consumption are probably caused by inappropriate use and that coordinated efforts to improve antimicrobial use internationally are desperately needed.

Geographic Variation In The Delivery Of Public Health Services: Understanding Causes And Consequences, Glen P. Mays

Health Management and Policy Presentations

The implementation and reach of evidence-based prevention and public health programs varies widely across the U.S., as does the availability of cross-cutting infrastructure and foundational capabilities required to support these interventions. This talk profiles ongoing research to uncover the causes and consequences of variation in public health delivery. This research points to policy and administrative strategies that can reduce inequities and inefficiencies in public health protections.

Examples Of Engaugements, Judith Longfield

Teaching Academy

The following form lists examples of EnGaugements.

Resurgence Of Measles In The U.S. Despite A Preventable Vaccine And School Entity, Tamara Troutman

Theses and Dissertations

Measles, a vaccine preventable, highly contagious infectious disease was once considered eradicated from the U.S. (Kutty et al., 2014). However measles outbreaks have recently reoccurred in the U.S. even despite the preventable vaccine and school entry laws. As evidenced by research, non-medical exemptions coupled with measles endemics worldwide have contributed to the recent U.S. measles outbreaks (Gustanaduy et al., 2014; Wang, Clymer, Davis Hayes, & Buttenheim, 2014; and World Health Organization, 2015). Even though compulsory vaccination may seem like an answer to decrease non-medical exemptions research has shown it could do more harm than good (Elliman & Bedford, 2013; Doshi …

A Comparison Of Nutrient Intake, Nutrient Adequacy, Diet Quality, And Obesity Prevalence In Low-Income Children (2-18 Yr) Based On Participation In The Supplemental Nutrition Assistance Program: Nhanes 2003-2010, Matthew J. Landry

Honors Capstones

No abstract provided.

Characterization Of A Novel Retrotransposon In New World Monkeys, Sreeja Sanampudi

Honors Capstones

No abstract provided.

Recycling Antibiotics Into Gumbos: A New Combination Strategy To Combat Multi-Drug-Resistant Bacteria, Marsha R. Cole, Jeffery A. Hobden, Isiah M. Warner

Faculty Publications

© 2015 by the authors; licensee MDPI. The emergence of multi-drug-resistant bacteria, coupled with the lack of new antibiotics in development, is fast evolving into a global crisis. New strategies utilizing existing antibacterial agents are urgently needed. We propose one such strategy in which four outmoded β-lactam antibiotics (ampicillin, carbenicillin, cephalothin and oxacillin) and a well-known antiseptic (chlorhexidine di-acetate) were fashioned into a group of uniform materials based on organic salts (GUMBOS) as an alternative to conventional combination drug dosing strategies. The antibacterial activity of precursor ions (e.g., chlorhexidine diacetate and β-lactam antibiotics), GUMBOS and their unreacted mixtures were studied …

High Frequency Of Active Hcv Infection Among Seropositive Cases In West Africa And Evidence For Multiple Transmission Pathways, Jennifer E. Layden, Richard O. Phillips, Shirley Owusu-Ofori, Fred Stephen Sarfo, Stephanie Kliethermes, Nallely Mora, Dorcas Owusu, Kenrad Nelson, Ohene Opare-Sem, Lara Dugas, Amy Luke, David Shoham, Joseph C. Forbi, Yury E. Khudyakov, Richard S. Cooper

Faculty Publications

Background. Sub-Saharan Africa (SSA) has one of the highest global hepatitis C virus (HCV) prevalence estimates. However, reports that suggest high rates of serologic false positives and low levels of viremia have led to uncertainty regarding the burden of active infection in this region. Additionally, little is known about the predominant transmission risk factors in SSA. Methods. We prospectively recalled 363 past blood donors (180 who were rapid screen assay [RSA] positive and 183 who were RSA negative at time of donation) to identify the level of active infection and risk factors for infection at a teaching hospital in Kumasi, …