Digital Commons Network^™

Plasma Membrane Restricted Rhogef Activity Is Sufficient For Rhoa-Mediated Actin Polymerization, Taofei Yin, Yi I. Wu

UCHC Articles - Research

The small GTPase RhoA is involved in cell morphology and migration. RhoA activity is tightly regulated in time and space and depends on guanine exchange factors (GEFs). However, the kinetics and subcellular localization of GEF activity towards RhoA are poorly defined. To study the mechanism underlying the spatiotemporal control of RhoA activity by GEFs, we performed single cell imaging with an improved FRET sensor reporting on the nucleotide loading state of RhoA. By employing the FRET sensor we show that a plasma membrane located RhoGEF, p63RhoGEF, can rapidly activate RhoA through endogenous GPCRs and that localized RhoA activity at the …

Assessment Of Mental Health Literacy Using A Multifaceted Measure Among A Chinese Rural Population, Yu Yu, Zi-Wei Liu, Mi Hu, Xi-Guang Liu, Hui-Ming Liu, Joyce Yang, Liang Zhou, Shui-Yuan Xiao

Psychology

Objectives: The present study aims to assess mental health literacy (MHL) using a standardised multifaceted 20-item instrument called Mental Health Knowledge Questionnaire (MHKQ) developed by the Chinese Ministry of Health, among a rural Chinese population.

Setting: Four villages in Liuyang county of Hunan province, China.

Participants: This was a cross-sectional study. A multistage cluster-sampling method was adopted, leading to a final sampling frame of 2377 residents aged 18–60 years from four villages of Liuyang county. Included in the study were residents aged 18–60 years living in their village for at least half a year; excluded were those not living in …

The Statistics Of Sensitivity Analyses, Alexander R. Luedtke, Ivan Diaz, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

Suppose one wishes to estimate a causal parameter given a sample of observations. This requires making unidentifiable assumptions about an underlying causal mechanism. Sensitivity analyses help investigators understand what impact violations of these assumptions could have on the causal conclusions drawn from a study, though themselves rely on untestable (but hopefully more interpretable) assumptions. Díaz and van der Laan (2013) advocate the use of a sequence (or continuum) of interpretable untestable assumptions of increasing plausibility for the sensitivity analysis so that experts can have informed opinions about which are true. In this work, we argue that using appropriate statistical procedures …

Cerium Oxide Nanoparticle Treatment Ameliorates Peritonitis-Induced Diaphragm Dysfunction, Shinichi Asano, Ravikumar Arvapalli, Nandini D. Manne, Mani Maheshwari, Bing Ma, Kevin M. Rice, Vellaisamy Selvaraj, Eric Blough

MIIR Faculty Research

The severe inflammation observed during sepsis is thought to cause diaphragm dysfunction, which is associated with poor patient prognosis. Cerium oxide (CeO₂) nanoparticles have been posited to exhibit anti-inflammatory and antioxidative activities suggesting that these particles may be of potential use for the treatment of inflammatory disorders. To investigate this possibility, Sprague Dawley rats were randomly assigned to the following groups: sham control, CeO₂ nanoparticle treatment only (0.5 mg/kg iv), sepsis, and sepsis+CeO₂ nanoparticles. Sepsis was induced by the introduction of cecal material (600 mg/kg) directly into the peritoneal cavity. Nanoparticle treatment decreased sepsis-associated impairments in …

Cseas Weekly Bulletin (October 5, 2015), Center For Southeast Asian Studies

CSEAS Bulletin

No abstract provided.

October 5, 2015, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Ada News - 10/05/2015, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Grand Valley Forum, Volume 040, Number 06, October 05, 2015, Grand Valley State University

2015-2016, Volume 40

Grand Valley Forum is Grand Valley State's faculty and staff newsletter, published from 1976 to the present.

Mary Blair, Emma Brooks

Communication Design: Design Pioneers

Mary Blair was one of the few women who played an important role in the history of animation. In the 1950’s, she was in a field dominated by men, but one man in particular saw great promise and potential in Blair’s whimsical and unique style, Walt Disney. Blair work on three Disney classics, Cinderella, Alice in Wonderland, and Peter Pan. She maintained a professional relationship with Walt Disney after she left to pursue freelance endeavors. Blair worked with him again for one last time with the It’s a Small World attraction at Disneyland. Mary Blair’s illustrations created fantasy environments that …

Updates In Academic Affairs - 10/05/15, Office Of The Provost And Vice President Of Academic Affairs

Updates in Academic Affairs

• University Libraries Dean Finalists to Present Public Talks on Campus
• Exploratory Advisors Help Students Zero in on a Program of Study
• Provost to Hold Forum for Non-Bargaining Unit Staff Members
• Fridays with Friends Mixers Scheduled through May

Support For The Inclusion Of Personal Value Preferences In Decision Support Systems, Donald L. Ariail, Janine Elyse Aronson, Richard Aukerman, Amine Khayati

Faculty Articles

We consider the important issue of including personal value preferences in decision support systems (DSS). Various personal differences have been shown to affect the acceptance, use, and effectiveness of DSS. Decision-making models offer a theoretical basis for the inclusion of various personal differences (including personal value preferences) in decision-making. Research in the field of psychology has long recognized the importance of values in both motivation and choice behavior. Other research has also found personal values to be relevant in decision-making. We posit that since personal values are important in the decision-making process, they should also be important in the support …

Commonwealth Times 2015-10-05

Commonwealth Times, 1969-

No abstract provided.

The Statesman, V. 59, I. 6, Stony Brook University

Stony Brook Statesman-Sucolian

v. 59;i. 6

The Tiger Vol. 109 Issue 39 2015-10-05, Clemson University

Tiger Newspapers 2015

No abstract provided.

Current, October 05, 2015, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

Scanlan Presents Inequality Underdevelopment And Global Food Riots, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Columbia Chronicle (10/05/2015)

Columbia Chronicle

Student newspaper from October 5, 2015, 2015 entitled The Columbia Chronicle. This issue is 40 pages and is listed as Volume 51, Issue 5. Cover story: "College addresses enrollment decline" Editor-in-Chief: Kyra Senese

Colonization Of Lutzomyia Verrucarum And Lutzomyia Longipalpis Sand Flies (Diptera: Psychodidae) By Bartonella Bacilliformis, The Etiologic Agent Of Carrion's Disease, James M. Battisti, Phillip G. Lawyer, Michael F. Minnick

Biological Sciences Faculty Publications

Bartonella bacilliformis is a pathogenic bacterium transmitted to humans presumably by bites of phlebotomine sand flies, infection with which results in a bi-phasic syndrome termed Carrion's disease. After constructing a low-passage GFP-labeled strain of B. bacilliformis, we artificially infected Lutzomyia verrucarum and L. longipalpis populations, and subsequently monitored colonization of sand flies by fluorescence microscopy. Initially, colonization of the two fly species was indistinguishable, with bacteria exhibiting a high degree of motility, yet still confined to the abdominal midgut. After 48h, B. bacilliformis transitioned from bacillus-shape to a non-motile, small coccoid form and appeared to be digested along with …

Green Building Action Plan, Jerry Brown Gov.

Long Range Campus Planning Archive

No abstract provided.

Castellano Presents Cultural Practice Of Therapeutic Jurisprudence In Felony Mental Health Courts, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

What's Happening: October 5, 2015, Maine Medical Center

What's Happening

No abstract provided.

Medicare's Post-Acute Care Payment: An Updated Review Of The Issues And Policy Proposals, Sally Coberly

National Health Policy Forum

Medicare spending on post-acute care provided by home health agencies, skilled nursing facilities, inpatient rehabilitation facilities, and long-term care hospitals accounted for about 10 percent of total program outlays in 2013. The Medicare Payment Advisory Commission and others have noted several long-standing problems with the payment systems for post-acute care and have suggested refinements to Medicare's post-acute care payment systems that are intended to encourage the delivery of appropriate care in the right setting for a patient's condition. The Patient Protection and Affordable Care Act of 2010 contained several provisions that affect the Medicare program's post-acute care payment systems, as …

The New Hampshire, Vol. 105 [106], No. 09 (Oct. 5, 2015), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 105, but it is the 106th volume in the series.

The Utah Statesman, October 5, 2015, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

The Rider (2015-10-05), Jesus Sanchez

The Rider Archives

Vol.1 No.6

Uab Study Finds Possible Frontline Therapy For Older Patients With Hodgkin Lymphoma, Staff

Browse All News

No abstract provided.

Diagnostic Options And Challenges For Dengue And Chikungunya Viruses., Stacey K. Mardekian, Amity L. Roberts, Phd, D(Abmm)

Department of Medical Genetics Faculty Papers

Dengue virus (DENV) and Chikungunya virus (CHIKV) are arboviruses that share the same Aedes mosquito vectors and thus overlap in their endemic areas. These two viruses also cause similar clinical presentations, especially in the initial stages of infection, with neither virus possessing any specific distinguishing clinical features. Because the outcomes and management strategies for these two viruses are vastly different, early and accurate diagnosis is imperative. Diagnosis is also important for surveillance, outbreak control, and research related to vaccine and drug development. Available diagnostic tests are aimed at detection of the virus, its antigenic components, or the host immune antibody …

College Voice Vol. 99 No. 2, Connecticut College

2015-2016

No abstract provided.

2015-16 Sidore Lecture Series Explores Implications Of Sequencing Human Genomes, Katie Umans

Media Relations

No abstract provided.

Testing The Concurrent Validity Of A Naturalistic Upper Extremity Reaching Task, Sydney Y. Schaefer, C. R. Hennge

Kinesiology and Health Science Faculty Publications

Point-to-point reaching has been widely used to study upper extremity motor control. We have been developing a naturalistic reaching task that adds tool manipulation and object transport to this established paradigm. The purpose of this study was to determine the concurrent validity of a naturalistic reaching task in a sample of healthy adults.This task was compared to the criterion measure of standard point-to-point reaching. Twenty-eight adults performed unconstrained out-and-back movements in three different directions relative to constant start location along midline using their nondominant arm. In the naturalistic task, participants manipulated a tool to transport objects sequentially between physical targets …