Digital Commons Network^™

Cell-Surface Glycan-Lectin Interactions For Biomedical Applications, Benavente Maria Carolina Rodriguez

Electronic Theses and Dissertations 2010 - 2019

Carbohydrate recognition is one of the most sophisticated recognition processes in biological systems, mediating many important aspects of cell-cell recognition, such as inflammation, cell differentiation, and metastasis. Consequently, lectin-glycan interactions have been intensively studied in order to mimic their actions for potential bioanalytical and biomedical applications. Galectins, a class of ß-galactoside-specific animal lectins, have been strongly implicated in inflammation and cancer. Galectin-3 is involved in carbohydrate-mediated metastatic cell heterotypic and homotypic adhesion via interaction with Thomsen-Friedenreich (TF) antigen on cancer-associated MUC1. However, the precise mechanism by which galectin-3 recognizes TF antigen is poorly understood. Our thermodynamic studies have shown that …

Academic Task Avoidance And Achievement As Predictors Of Peer Status During The Early Primary School Years, Ashley D. Richmond

Electronic Theses and Dissertations 2010 - 2019

Given the diverse and substantial developmental outcomes associated with low peer acceptance, it is important to research its potential predictors. However, the developmental antecedents are not likely restricted to simple, one-lagged links within the same domain. Rather, peer status may stem from a developmental sequence of effects across several domains, particularly across those that develop at the same time and in the same environment as peer status. A developmental cascade model is best used to capture sequential changes over time, across multiple domains, and during sensitive periods of development Academic motivation and achievement likely exemplify predictors that would affect peer …

Channel Assignment In Multi-Radio Networks, Amalya Mihnea

Electronic Theses and Dissertations 2010 - 2019

Channel assignment in multi-radio networks is a topic of great importance because the use of multiple channels and multiple radios reduces interference and increases the network throughput. The goal of our research is to design algorithms that maximize the use of available resources while providing robustness to primary users that could reclaim one or more channels. Our algorithms could be used in ad hoc networks, mesh networks, and sensor networks where nodes are equipped with multiple radios. We design algorithms for channel assignment which provide robustness to primary users without assuming an accurate primary user behavior model. We also compute …

Toward A Fundamental Right To Evade Law? Protecting The Rule Of Unequal Racial And Economic Power In Shelby County And State Farm, Martha T. Mccluskey

Journal Articles

To rationalize its ruling on voting rights, Shelby County, Alabama v. Holder develops a constitutional vision of passivity in the face of institutionalized power to violate the law. This essay compares Shelby County to State Farm Mutual Automobile v. Campbell, a 2003 Supreme Court ruling involving a different subject area, state punitive damage awards. In both, the Court asserts newly articulated judicial power to override other branches, not to protect human rights, but rather to expand institutionalized immunity from those rights. On the surface, the Court’s rejection of state sovereignty in State Farm (protecting multistate corporations from high punitive damages) …

Archaeological And Historical Investigations Of The Robert Newsom Farmstead (23cy497), Callaway County, Missouri, James Adam Halpern

Graduate Theses/Dissertations

Scholarly research on slavery in the U.S. has focused on large commercial plantations in the Old South. Yet a majority of slaveholders and nearly half of the enslaved lived in smaller slaveholding houses and family farms (Burke 2010:4). This study helps redress the dearth of research on small slaveholdings through study of the Robert Newsom Farmstead, or "Celia" Site (23CY497), located in Callaway County, Missouri. The research goal is to model the antebellum spatial organization of the landholding, thereby increasing our understanding of slavery at the Newsom site and on non-plantation slaveholdings generally. This was accomplished through collection and analysis …

Sisters Before The Fall, Heather Lanae Captain

Graduate Theses/Dissertations

This thesis comprises the first fourteen chapters of a fiction entitled "Sisters Before the Fall", which brings to the forefront extreme, yet, real abuses faced by women in the Middle East and the northeastern countries of Africa. Those abuses are the result of social, political, and cultural influences, and include general repression of women and girls, female genital mutilation, marriage of prepubescent girls, and the slave trade. A female American volunteer and a female Hispanic doctor meet these women in a humanitarian compound in western Sudan. As they work together to overcome challenges brought on by war, they realize they …

Factors Affecting Anterior Knee Pain In Post-Aclr Comparing Patellar Tendon And Hamstring Tendon Autografts, Alexandria Annalicia Jauregui-Dusseau

Graduate Theses/Dissertations

Anterior cruciate ligament (ACL) injuries are frequent athletic and non-athletic injuries that impact a person's functional and athletic capability. ACL injuries generally require surgical reconstruction. The most popular graft types include patellar tendon (PT) and hamstring tendon (HT) autografts. PT autografts have been blamed for chronic anterior knee pain (AKP) and extensor mechanism deficits. This study compared the PT and HT autografts and their impact on AKP in subjects who underwent anterior cruciate ligament reconstruction (ACLR). Data were gathered from existing patient data from rehabilitation therapy records. Additional factors were also analyzed to determine the effect on post-ACLR pain. Post-treatment …

Maximum Entropy Modeling Of Indiana Bat (Myotis Sodalis) Maternity Roost Habitat, Joseph Robert Lemen

Graduate Theses/Dissertations

Since 1967, the Indiana bat (Myotis sodalis) has been on the U.S. Endangered Species list due to disruption of hibernating bats in caves, summer habitat degradation, and more recently, the onset of White-nose Syndrome. The purpose of this study is to evaluate landscape variables associated with Indiana bat maternity roost trees in an attempt to better understand what factors play a role in their distribution in north central Missouri. I tracked reproductive female Indiana bats to 20 different primary and secondary roost trees; these are roosts that had multiple bats visit them on multiple occasions. GPS location data for these …

Functional Connection Between Yeast Dynamin And Retromer At The Endosome, Christopher Robert Trousdale

Graduate Theses/Dissertations

Intracellular trafficking from the late endosome to Golgi in cells is termed retrograde transport, essential for recycling of important macromolecules including cell membrane receptors. Retrograde transport is regulated by a family of proteins known as the "Retromer” composed of 5 VPS proteins (Vps5, Vps17, Vps26, Vps29, and Vps35). Retromer acts as the coat proteins for vesicles emerging from late endosomes. Loss of Retromer function has been previously implicated in both Parkinson's and Alzheimer's disease. Vps1, a yeast dynamin-like protein, plays a role in intracellular trafficking. Vps1 has been shown to localize at the endocytic sites to promote pinching off of …

Thermal Damping And Retardation In Karst Conduits, A. J. Luhmann, Matthew D. Covington, J. M. Myre, Matija Perne, S. W. Jones, E. C. Alexander Jr., M. O. Saar

Geosciences Faculty Publications and Presentations

Water temperature is a non-conservative tracer in the environment. Variations in recharge temperature are damped and retarded as water moves through an aquifer due to heat exchange between water and rock. However, within karst aquifers, seasonal and short-term fluctuations in recharge temperature are often transmitted over long distances before they are fully damped. Using analytical solutions and numerical simulations, we develop relationships that describe the effect of flow path properties, flow-through time, recharge characteristics, and water and rock physical properties on the damping and retardation of thermal peaks/troughs in karst conduits. Using these relationships, one can estimate the thermal retardation …

Underreporting Of Wildlife-Vehicle Collisions Does Not Hinder Predictive Models For Large Ungulates, Nathan P. Snow, William F. Porter, David M. Williams

United States Department of Agriculture Wildlife Services: Staff Publications

Conflicts from wildlife–vehicle collisions (WVCs) pose serious challenges for managing and conserving large ungulates throughout the world. However, underreporting of large proportions of WVCs (i.e., two-thirds of WVCs in some cases) creates concern for relying on governmental databases to inform management strategies of WVCs. Our objective was to test the sensitivity of WVC studies to underreporting using 2 species of large ungulates that experience substantial incidences of collisions but exist in different environmental settings: white-tailed deer (Odocoileus virginianus) in agricultural-dominated central Illinois and moose (Alces alces) in forest-dominated western Maine, USA. We estimated baseline relationships between …

Discrepancy Between Parents And Children In Reporting Of Distress And Impairment: Association With Critical Symptoms, Laura Bein, Megan Lynn Petrik, Stephen M. Saunders, James V. Wojcik

Psychology Faculty Research and Publications

Background: We examined discrepant parent–child reports of subjective distress and psychosocial impairment.

Method: Parent–child pairs (N = 112 pairs) completed the Health Dynamics Inventory at intake for outpatient therapy.

Results: Average parent scores were significantly higher than average child scores on distress, impairment, and externalizing symptoms, but not internalizing symptoms. There were significant associations between parent–child discrepancy (i.e. children who reported greater distress or impairment than parents or vice versa) and child endorsement of several notable symptoms (rapid mood swings, panic, nightmares, and suicidal ideation).

Conclusion: Parents tended to report more externalizing symptoms, distress, and impairment than children reported; …

Maternal Functioning Differences Based On Adhd Subtype, Kelsey Ann Weinberger, Denise M. Gardner, Alyson C. Gerdes

Psychology Faculty Research and Publications

Objective: Maternal functioning differences in parenting stress, parental efficacy, and parenting behaviors were examined for mothers of children with ADHD. Method: Participants included 29 mothers of children with ADHD, Predominantly Inattentive Type (ADHD-I) and 38 mothers of children with ADHD, Predominantly Hyperactive-Impulsive or Combined Type (ADHD-HI/C). Results: Findings suggest that mothers of children with ADHD-HI/C reported significantly greater parenting stress and engaged in more negative parenting behaviors than mothers of children with ADHD-I. Conclusion: This study suggests that tailoring behavioral parent training based on ADHD subtype may be particularly helpful for parents of children with ADHD-HI/C.

Seasonal Shifts In Diet And Gut Microbiota Of The American Bison (Bison Bison), Gaddy T. Bergmann, Joseph Craine, Michael S. Robeson, Noah Fierer

United States Department of Agriculture Wildlife Services: Staff Publications

North American bison (Bison bison) are becoming increasingly important to both grassland management and commercial ranching. However, a lack of quantitative data on their diet constrains conservation efforts and the ability to predict bison effects on grasslands. In particular, we know little about the seasonality of the bison diet, the degree to which bison supplement their diet with eudicots, and how changes in diet influence gut microbial communities, all of which play important roles in ungulate performance. To address these knowledge gaps, we quantified seasonal patterns in bison diet and gut microbial community composition for a bison herd in …

Spatiotemporal Dynamics In Identification Of Aircraft–Bird Strikes, Tara J. Conkling, James A. Martin, Jerrold L. Belant, Travis L. Devault

United States Department of Agriculture Wildlife Services: Staff Publications

A primary concern for human–wildlife interactions is the potential impacts resulting from wildlife (primarily birds) collisions with aircraft. The identification of species responsible for collisions with aircraft is necessary so that airport management can develop effective strategies to reduce strikes with those species. Of particular importance in developing such strategies is the identification of regional, seasonal, and temporal patterns in collisions with unidentified bird species that may limit the effectiveness of regional habitat management to reduce bird strikes. The authors analyzed 105,529 U.S. civil aviation strike records from 1990 to 2012 in the FAA’s National Wildlife Strike Database to examine …

‘Feed-Forward: Exploring The Staff And Student Experience Of Technology Facilitated Feedback - Can Technology Support And Engage Staff And Students In Dialogic Feedback?’, R Lowes, E Purnell, Helen Bowstead

School of Law, Humanities and Social Sciences

Aims of project: to explore the use of new feedback processes within four module groups in the Plymouth Business School; to evaluate how two of the institutionally provided learning technologies, Moodle and PebblePad, could support and enhance the online feedback experience for staff/students.Background/context to project: ELC101, ELC201, ELC305 and ELC307 are four English language modules where we seek to develop students’ capacity to self-regulate and develop strategies for autonomous learning, in order to further the development of their English language skills. We have noted over the years that students do not seem to engage with feedback as much as we …

Defining Competence In Obstetric Epidural Anaesthesia For Inexperienced Trainees, E. J. Drake, J. Coghill, J. R. Sneyd

Peninsula Medical School

Background: Cumulative sum (CUSUM) analysis has been used for assessing competence of trainees learning new technical skills. One of its disadvantages is the required definition of acceptable and unacceptable success rates. We therefore monitored the development of competence amongst trainees new to obstetric epidural anaesthesia in a large public hospital. Methods: Obstetric epidural data were collected prospectively between January 1996 and December 2011. Success rates for inexperienced trainees were calculated retrospectively for (1) the whole database, (2) for each consecutive attempt and (3) each trainee's individual overall success rate. Acceptable and unacceptable success rates were defined and CUSUM graphs generated …

Clinical Effectiveness And Cost-Effectiveness Of The Rehabilitation Enablement In Chronic Heart Failure (Reach-Hf) Facilitated Self-Care Rehabilitation Intervention In Heart Failure Patients And Caregivers: Rationale And Protocol For A Multicentre Randomised Controlled Trial, R. S. Taylor, C. Hayward, V. Eyre, J. Austin, R. Davies, P. Doherty, K. Jolly, J. Wingham, R. Van Lingen, C. Abraham, C. Green, F. C. Warren, N. Britten, C. J. Greaves, S. Singh, S. Buckingham, K. Paul, H. Dalal

School of Nursing and Midwifery

Introduction: The Rehabilitation EnAblement in CHronic Heart Failure (REACH-HF) trial is part of a research programme designed to develop and evaluate a health professional facilitated, home-based, self-help rehabilitation intervention to improve self-care and health-related quality of life in people with heart failure and their caregivers. The trial will assess the clinical effectiveness and cost-effectiveness of the REACH-HF intervention in patients with systolic heart failure and impact on the outcomes of their caregivers. Methods and analysis: A parallel two group randomised controlled trial with 1:1 individual allocation to the REACH-HF intervention plus usual care (intervention group) or usual care alone (control …

Interventions To Improve Antimicrobial Prescribing Of Doctors In Training: The Impact (Improving Antimicrobial Prescribing Of Doctors In Training) Realist Review, Geoff Wong, Nicola Brennan, Karen Mattick, Mark Pearson, Simon Briscoe, Chrysanthi Papoutsi

Peninsula Medical School

No abstract provided.

Serotonin Stimulates Secretion Of Exosomes From Microglia Cells, K Glebov, M Löchner, R Jabs, T Lau, O Merkel, P Schloss, C Steinhäuser, J Walter

Peninsula Medical School

Microglia are resident immune cells in the brain and exert important functions in the regulation of inflammatory processes during infection or cellular damage. Upon activation, microglia undergo complex morphological and functional transitions, including increased motility, phagocytosis and cytokine secretion. Recent findings indicate that exosomes, small vesicles that derive from fusion of multivesicular bodies with the plasma membrane, are involved in secretion of certain cytokines. The presence of specific receptors on the surface of microglia suggests communication with neurons by neurotransmitters. Here, we demonstrate expression of serotonin receptors, including 5‐HT2a,b and 5‐HT4 in microglial cells and their functional involvement in the …

Advanced Ligo, Tiffany Summerscales, Ligo Scientific Collaboration

Faculty Publications

No abstract provided.

Sensory Processing And Conducive Study Environments, Katrina Kotta

Undergraduate Theses and Senior Projects

No abstract provided.

Peer Mentorship And Cultural Capital Among High School Students, Crescentia Fatima Thomas

University of the Pacific Theses and Dissertations

Peer mentorship and school connectedness was reviewed here through social capital and cultural capital lenses. The relationship has been interwoven to create an idea of how to shape an environment which can foster cohesiveness among students. Peer mentorship has been indicated as a significant contribution to cross-aged grade levels with the improvement in attendance, behavior, social activities, and school awareness—which are encompassed in the term, school connectedness. In regards to college access and college knowledge, peer mentorship here, assists with the transfer of social capital and cultural capital. Students were able to develop relationships and gain knowledge passed on from …

An Analysis Of Port Service Quality And Customer Satisfaction: The Case Of Korean Container Ports, Gi Tae Yeo, Vinh V. Thai, Sae Yeon Roh

Plymouth Business School

No abstract provided.

Using Campinas- Barcode’S Cultural Competency Model And Roach's Model Of Caring To Enhance Self-Perception Of Cultural Competence And Perceived Knowledge Of Caring Among Physicians, Nurse Practitioners, And Community Nurses., Alicia Bannis

Electronic Theses and Dissertations 2010 - 2019

As the culturally diverse healthcare population in the United States rises, the demand for healthcare providers who are knowledgeable in providing culturally competent care increases. Community health care providers are mandated to make cultural competence a priority in their clinical practice. This mandate challenges healthcare professionals to increase their knowledge of cultural diversity and caring behaviors and provide appropriate health care services to meet the needs of racially and ethnically diverse clients. For this project, an assessment of community healthcare providers’ self-perception of cultural competence and perceived knowledge of caring behaviors was untaken while posing the question: “How does a …

Use Of An Electronic Educational Module To Educate Advanced Practice Nurses On Preventive Care Protocol For Immunocompromised Patients, Simi Jesto Joseph Dr, Audrey Klopp Dr

Manipal Journal of Nursing and Health Sciences

Immunocompromised patients are at increased risk of infections and certain cancers due to the immunosuppressed body as well as the immunosuppressive agents. Despite American national organizations’ specific guidelines for immunocompromised patients, reported vaccination rates and provider compliance on preventive services is low. The aim of this study was to assess knowledge, attitude and clinical practice among Advanced Practice Nurses (APN) in preventive care for immunocompromised patients and educating APNs to improve their knowledge and practice skills using an evidence-based preventive care protocol. Methods: APN members of Illinois Society of Advanced Practice Nurses (ISAPN) organization were surveyed by a needs assessment …

What Remains Of The Intersubjective?: On The Presencing Of Self And Other, Paul Simpson

School of Geography, Earth and Environmental Sciences

No abstract provided.

Coupled Techniques For Arsenic Speciation In Food And Drinking Water: A Review, Bashdar Sadee, M. E. Foulkes, S. J. Hill

School of Geography, Earth and Environmental Sciences

No abstract provided.

An Investigation Into The Effects Of Different Types Of Exercise On The Maintenance Of Approach Motivation Levels, J. A.S. Lowenstein, K. Wright, A. Taylor, N. J. Moberly

Peninsula Medical School

No abstract provided.

Psychometric Evaluation Of The Newcastle Satisfaction With Nursing Scales, Michela Piredda, Ercole Vellone, Giovanni Piras, Roberta Fida, Jos M. Latour, Maria Matarese, Rosaria Alvaro, Marinis Mg De

School of Nursing and Midwifery

No abstract provided.