Digital Commons Network^™

Ca2+ Diffusion Through Endoplasmic Reticulum Supports Elevated Intraterminal Ca2+ Levels Needed To Sustain Synaptic Release From Rods In Darkness., Minghui Chen, Matthew J. Van Hook, Wallace B. Thoreson

Journal Articles: Ophthalmology

UNLABELLED: In addition to vesicle release at synaptic ribbons, rod photoreceptors are capable of substantial slow release at non-ribbon release sites triggered by Ca(2+)-induced Ca(2+) release (CICR) from intracellular stores. To maintain CICR as rods remain depolarized in darkness, we hypothesized that Ca(2+) released into the cytoplasm from terminal endoplasmic reticulum (ER) can be replenished continuously by ions diffusing within the ER from the soma. We measured [Ca(2+)] changes in cytoplasm and ER of rods from Ambystoma tigrinum retina using various dyes. ER [Ca(2+)] changes were measured by loading ER with fluo-5N and then washing dye from the cytoplasm with …

Characterizing Demographicparameters Across Environmental Gradients: A Case Study With Ontario Moose, Garrett M. Street, Tal Avgar, Arthur R. Rodgers, John M. Fryxell

Wildland Resources Faculty Publications

Population-level demographic characteristics as estimated by standard logistic growth models (i.e., carrying capacity and intrinsic growth rate) should vary with changes in habitat quality and availability of resources. However, few published studies have tested this hypothesis by comparing population growth rates across broad bioclimatic gradients, and fewer still the carrying capacities of those populations. We used time series data on moose (Alces alces) population densities based on aerial census and hunter harvest data for 34 management units across Ontario to estimate local carrying capacities and intrinsic growth rates. These population parameters were then regressed against associated habitat covariates for each …

Abq Free Press, August 12, 2015, Abq Free Press

ABQ Free Press

No abstract provided.

Nanoparticle Interaction At Cellular And Subcellular Levels As Analyzed By Electron Microscopy For Biomedical Application, Thikra Mustafa

Theses and Dissertations

Nanotechnology is a multidisciplinary field of science. The merger of nanotechnology and biotechnology has led to the introduction of a new field of science called bionanotechnology. Bionanotechnology employs extremely small, engineered materials to perform tasks within biological systems. This new technology has benefits in many different sectors, including cancer fighting, disease detection, and medical imaging. The application of nanotechnology in biology and medicine offers exciting new possibilities. A nanoparticle (NP) --an extremely small, two- or three -dimensional object having a size ranging from 1-100nm--is the type of nanomaterial utilized in bionanotechnology applications. Gold nanoparticles (AuNPs) and iron oxide nanoparticles (IONPs) …

Senyawa Steroid Dari Kulit Batang Dysoxylum Alliaceum Dan Aktivitasnya Terhadap Sel Kanker Payudara Mcf-7, Ois Nurcahyanti, Euis Julaeha, Tri Mayanti

Chimica et Natura Acta

Dysoxylum merupakan salah satu genus yang memiliki metabolit sekunder dan aktivitas yang beragam, salah satu aktivitas yang menarik adalah mampu bertindak sebagai agen P-gp pada sel kanker payudara MCF-7. Kulit batang D.alliaceum dimaserasi berturut–turut dengan n-heksana, etil asetat dan metanol. Ekstrak n-heksan dipisahkan dan dimurnikan dengan berbagai teknik kromatografi dipandu dengan analisis kromatografi lapis tipis diperoleh dua senyawa stigmast-5-en-3β-ol (1), stigmasterol (2). Struktur kimia senyawa tersebut telah ditetapkan berdasarkan intrepretasi data-data spektroskopi dan dibandingkan dengan data spektra dari penelitian sebelumnya. Semua isolat senyawa dievaluasi aktivitas sitotoksiknya terhadap sel kanker payudara MCF-7. Senyawa 1 dan 2 dirujuk dari literatur menunjukkan aktivitas …

From The Commons To The Spartan Floor: Enhancing Digital Literacy Through Technology-Integrated Spaces, Christina Mune, Sharon Thompson

Re-think it: Libraries for a New Age

While Learning and Research Commons have become, well, common, in university libraries, San Jose State University’s Library has sought to move beyond the Commons or even makerspaces to create a technology-integrated learning environment within the library that addresses the digital literacy needs of our students while providing the comfortable, collaborative areas they seek. An entire floor of the library has been dedicated to this effort and christened the “Spartan Floor” (in honor of our school mascot). The Spartan Floor is made up of four components:

• Integrated technologies, including mediascapes, a touchscreen table, an interactive whiteboard, and digital signage.

• Student Computing …

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Inviting Children Into Project Work., Carolyn P. Edwards, Kay Springate

Department of Child, Youth, and Family Studies: Faculty Publications

This brief article describes the approach to long-term projects used with young children in the city-run preschools of Reggio Emilia, Italy. In particular, it explains how the learning environment and the guidance of the teacher invite them into a project, then help them sustain and conclude it.

From Dandelion Seed To Cottage Garden: The Transformation Of User Experience In The Msu Libraries, Christine Tobias

Re-think it: Libraries for a New Age

The user experience movement is gaining momentum in public and academic libraries. While it is not a new phenomenon, its adoption and adaptation into a library’s organizational culture can bring unexpected challenges. In June 2014, the MSU Libraries created a User Experience (UX) unit in the Public Services division and in a short time, has established a solid and reputable team of UX practitioners. This success, however, was not achieved overnight.

The transformation of user experience at the MSU Libraries began as a solo effort of one librarian who understood the importance of assessment practices in library services. Through planting …

Role Of Cdc37 In The Structural Proofreading Of Erbb Receptor Tyrosine Kinases, Wenjun Liu

Open Access Dissertations

Folding and maturation of most protein kinases require chaperone assistance. In higher eukaryotes, CDC37 is the predominant cochaperone that facilitates the transfer of kinase clients to Hsp90. Kinase recognition is thought to occur through the N-terminal domain, which has, thus far, eluded structure determination. Client processing requires phosphorylation of the N-terminal tail at Ser13 by the protein kinase, CK2 (casein kinase 2). How phosphorylation alters the molecular properties of CDC37 is not understood. We show that phosphorylation at Ser13 induces a large shift towards a more compact structure, based on ANS fluorescence, while modestly increasing the secondary structure. Moreover, this …

Urban Art And Uneven Development: The Geography Of “Artwashing” In Miami And Philadelphia, Mackenzie Sheldon

Open Access Theses

This thesis explores the intersections of art and urban redevelopment by evaluating the strategic uses of urban art forms in distressed neighborhoods of Philadelphia and Miami. Specifically, this thesis takes to task the trend of “artwashing” in which developers appropriate and aestheticize markers of urban decay in order to market real estate to consumers seeking an industrial chic backdrop. While most discussions of artwashing center on the upgrading of austere industrial buildings, I believe the term should also be applied to the appropriation of urban art forms for neighborhood rebranding purposes. In recent years, the commissioning of street art has …

Host Promiscuity In Symbiont Associations Can Influence Exotic Legume Establishment And Colonization Of Novel Ranges, Metha M. Klock, Luke G. Barrett, Peter H. Thrall, Kyle E. Harms

Faculty Publications, Environmental Studies

Aim
Invasive Acacia species have negatively impacted natural areas in multiple regions around the globe. Almost 400 Acacia species have been introduced outside their native ranges in Australia; approximately 6% have become invasive, 12% are naturalized, and 82% have no record of naturalization or invasion. This variation in invasiveness provides a comparative framework in which to examine mechanisms that either promote or constrain establishment and colonization of species in novel regions. Here, we experimentally examine the role that the legume–rhizobia symbiosis plays in the differential invasiveness of acacias introduced outside their native Australian ranges.
Location
Canberra, Australia.
Methods
We paired …

Scaling Up Teacher Professional Learning: How To Grow Teacher Knowledge While Growing School Networks, Emily J Klein, Reva Jaffe Walter, Meg Riordan

Department of Teaching and Learning Scholarship and Creative Works

This research reports data from case studies of three intermediary organizations facing the challenge of scaling up teacher learning. The turn of the century launched scaling up efforts of all three intermediaries, growing from intimate groups, where founding teachers and staff were key supports for teacher learning, to large multi-state organizations. The authors drew on data from three earlier qualitative studies of professional development at Big Picture Learning, Expeditionary Learning, and the Internationals Network, and reveal some of the benefits and challenges of taking teacher learning to scale.

Sandor Katz On A&S Tv Fermentation Is Culture Bubbling Over, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

The Shared Experiences Of Counselors Who Practice In Natural Environments, Bonnie King

LSU New Orleans Theses and Dissertations

The purpose of this qualitative, phenomenological study was to gain a deep understanding of the shared experiences of therapists who provide counseling in non-traditional, natural environment settings. Eight participants shared their experiences about counseling in nature. The primary research question for this study was: What are the shared experiences of counselors who provide nature-based counseling? A review of the literature of nature-based counseling provided benefits to spending time in nature, descriptions of various types of nature-based counseling, and ethical and legal issues that affect nature-based counselors.

Semi-structured interviews comprised of open-ended questions were used to collect data by phone and …

Chasin’ Tail In Southern Alabama: Delineating Programmed And Stimulus-Driven Grooming In Odocoileus Virginianus, Kyle Heine

LSU New Orleans Theses and Dissertations

This study examined variation in ectoparasite density and grooming behavior of naturally occurring white-tailed deer (Odocoileus virginianus) in southwest Alabama. Stimulus-driven grooming as well as the intraspecific body size and vigilance principles of programmed grooming were tested. During the rut, males had a higher average tick (Ixodidae) density than females and exhibited complete separation of tick parasitism between non-rutting and rutting periods, supporting the vigilance principle. Stimulus-driven grooming was supported, as both fawns and yearlings had significantly higher fly (Hippoboscidae) and combined fly/tick densities than adults, and fawns oral groomed at a significantly higher rate than adults, even …

Stretch-Induced Increase In Cardiac Contractility Is Independent Of Myocyte Ca2+ While Block Of Stretch Channels By Streptomycin Improves Contractility After Is-Chemic Stunning, Samhita Rhodes, Amadou K. S. Camara, Mohammed Aldakkak, James S. Heisner, David F. Stowe

Open Access Publishing Support Funded Articles

Stretching the cardiac left ventricle (LV) enhances contractility but its effect on myoplasmic [Ca²⁺] is controversial. We measured LV pressure (LVP) and [Ca²⁺] as a function of intra-LV stretch in guinea pig intact hearts before and after 15 min global stunning ± perfusion with streptomycin (STM), a stretch-activated channel blocker. LV wall [Ca²⁺] was measured by indo-1 fluorescence and LVP by a saline-filled latex balloon inflated in 50 μL steps to stretch the LV. We implemented a mathematical model to interpret cross-bridge dynamics and myofilament Ca²⁺ responsiveness from the instantaneous relationship between [Ca …

The Predictive Utility Of Emotional Deficits And Callous-Unemotional Traits For Important Antisocial Outcomes In Juvenile Justice-Involved Youth, Laura C. Thornton

LSU New Orleans Theses and Dissertations

The current study investigated the predictive utility of callous-unemotional (CU) traits and emotional facilitation to distress (EFD) for multiple antisocial outcomes in a sample of juvenile justice-involved males. Although CU traits and EFD did not generally interact to predict antisocial outcomes, CU traits were a consistent predictor of total, proactive, and reactive forms of aggression over 18 months. Similarly, CU traits and time interacted to predict total and violent self-reported offending, such that CU traits were positively associated with both outcomes, but this association weakened over the 18 month timeframe. Racial and ethnic differences only emerged for the prediction of …

Microbial Ligand Costimulation Drives Neutrophilic Steroid-Refractory Asthma, Sabelo Hadebe, Frank Kirstein, Kaat Fierens, Kong Chen, Rebecca A. Drummond, Simon Vautier, Sara Sajaniemi, Graeme Murray, David L. Williams, Pierre Redelinghuys, Todd A. Reinhart, Beth A.Fallert Junecko, Jay K. Kolls, Bart N. Lambrecht, Frank Brombacher, Gordon D. Brown, Bernhard Ryffel

ETSU Faculty Works

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Asthma is a heterogeneous disease whose etiology is poorly understood but is likely to involve innate responses to inhaled microbial components that are found in allergens. The influence of these components on pulmonary inflammation has been largely studied in the context of individual agonists, despite knowledge that they can have synergistic effects when used in combination. Here we have explored the effects of LPS and β-glucan, …

Food Insecurity Reported By Children, But Not By Mothers, Is Associated With Lower Quality Of Diet And Shifts In Foods Consumed, Jennifer Bernal, Edward A. Frongillo Jr., Juan A. Rivera

Faculty Publications

Household food security shows little indication of nutrient inadequacy among children, according to reports made by parents. We examined the associations of food insecurity as reported by children and mothers with children’s consumption of energy, macronutrients such as vitamin A, calcium, iron and zinc, and selected foods, and whether these associations differed by child’s gender. This cross-sectional study had non-probabilistic 128 Venezuelan mother–child pairs. We assessed food insecurity and management strategies in children using 10- and nine-item instruments, respectively. Mothers’ report of food insecurity came from a previously validated 12-item instrument. Nutrient intake of children was assessed with a 67-item …

Caring For The Land, Serving People: Creating A Multicultural Forest Service In The Civil Rights Era, Donna Lynn Sinclair

Dissertations and Theses

This qualitative study of representative bureaucracy examines the extension and limitations of liberal democratic rights by connecting environmental and social history with policy, individual decision making, gender, race, and class in American history. It documents major cultural shifts in a homogeneous patriarchal organization, constraints, advancement, and the historical agency of women and minorities. "Creating a Multicultural Forest Service" identifies a relationship between natural and human resources and tells a story of expanding and contracting civil liberties that shifted over time from women and people of color to include the differently-abled and LGBT communities. It includes oral history as a key …

Vitamin D Deficiency And Infertility: A Systematic Review, Susanne Stoddard Sollis

Student Works

Vitamin D regulates calcium and phosphorus homeostasis in the body. In recent years, studies have been conducted examining the role vitamin D plays in reproduction. Vitamin D deficiency is associated with infertility, decreased pregnancy rates, and hormonal changes. Asians appear to have a reverse correlation with pregnancy rates and vitamin D levels. There are some conflicting studies regarding vitamin D levels in relationship to infertility. This paper reviews the most recent literature focusing on the relationship between vitamin D status and infertility. This review evidences vitamin D levels >30 ng/mL result in improved fertility outcomes.

An Insight Into The Role Of Vitamins Other Than Vitamin D On Bone, Robert E. Salazar, Jameela Banu

Health & Biomedical Sciences Faculty Publications

Vitamins are essential micronutrients for normal development. Great emphasis has been placed on vitamin D for bone development and maintenance. However, other vitamins also influence bone health. While some of them are more beneficial to bone and increase bone mass by increasing bone formation, calcium deposition and stimulate osteoblastogenesis, higher concentrations of others have deleterious effects causing fragile bones and increasing the risk of fractures. Knowledge about the effects of these vitamins will help in better maintenance of bone. This review focuses on the information available on vitamins A,B,C,E and K on bone health. Existing information supports vitamin C and …

Creativity: The Critical Element For Mission Success, Luca Maresi, Alessandro Zuccaro Marchi

Small Satellite Conference

Can creativity be the critical element for the success of a Space Mission? Problem solving methodologies, as brainstorming, are familiar for finding solutions to technical problems. The analytical skills to solve problems and the creativity required to invent new products may appear similar, but they are profoundly different. Creativity requires a different mindset than problem solving. In sectors where the engineering process depends on creative thinkers new ways of technology development need to be defined. The objective of the mission Rosetta to land on a comet is well defined. For most of cubesat missions, the problem is posed the other …

Faculty Expectations Toward Their Online Courses: Are They On The Same Screen With Their Students?, John A. Huss, Shannon Eastep

Journal of Inquiry and Action in Education

This action research study explored attitudes and expectations of faculty at a Midwestern university who taught at least one fully online course during 2014. The study focused on instructor perceptions toward and experiences with web-based instruction, particularly in the critical areas of assessment and feedback; course organization; interaction with students; course flexibility; and overall communication. Findings were then compared to student responses from the authors’ previous study. A mixed-methods electronic survey blended a quantitative component in the form of 21 fixed response items with a qualitative element accomplished through two narrative response questions where content analysis was used to compress …

Action Research: Investigating Educators Feelings About Rubrics, Alisson Riggie, Lauren Metzen, Julie Goodrich, Whitney Yorio, Kasey Poloncarz, David Rose, Joshua Walker, Maria Anne Ceprano

Journal of Inquiry and Action in Education

Teacher candidates who worked with small groups of children during a semester long pre-student teaching practicum developed four point rubrics for each of the lesson plans they created on a weekly basis. The scope of this practicum is discussed along with an action research project pertaining to the rubric assessments they utilized. Findings suggest ways this assessment practice might be enhanced in the future.

Growth, Mortality, And Availability Of Eastern Pacific Sailfish, Mark Daniel Fitchett

Open Access Dissertations

The Indo-Pacific sailfish, Istiophorus platypterus, has significant ecological and socioeconomic importance in the tropical eastern Pacific Ocean (EPO). It is caught as bycatch in tuna commercial fisheries, but targeted in economically important catch-and-release recreational fisheries. The sustainability of this valuable resource had not been successfully assessed due to poor fishery landings and effort data with unreliable demographic estimates for sailfish. The goal of this dissertation was to assess lifetime demographics and stock mortality rates of sailfish and to infer ecosystem dynamics that drive availability of sailfish to recreational fisheries. This dissertation developed a new age and growth model for sailfish …

Gsu View, 2015-08-10, Office Of Marketing And Communications

GSU View

Newsletter published by Governors State University 2007-current.

Annual Report, 2014-2015, University Of Arkansas, Fayetteville. College Of Engineering

College of Engineering Annual Report

No abstract provided.

Do Dog Owners Really Make Better Lovers?, Harold Herzog

'Animals and Us' Blog Posts

What does science say about the connection between love, sex and owning a dog?

Fifth Graders Blog With Preservice Teachers To Discuss Literature, Lindsay Yearta, Katie Stover, Rachel Sease

Reading Horizons: A Journal of Literacy and Language Arts

In this study, fifth grade students participated in a pen pal project with pre-service teachers where they blogged for eight weeks about the book, A Long Walk to Water, by Linda Sue Park. Partnerships were established to provide fifth grade students with an authentic audience in an effort to increase engagement in reading and writing. The authors posit that individualized instruction, access to an authentic audience, and the utilization of technology contributed to students' growth as readers, writers, and global citizens.