Digital Commons Network^™

Cytotoxicity Evaluation Of Surface-Coated Drug Nanocrystals, Alexandra R. Seybold

The Journal of Purdue Undergraduate Research

No abstract provided.

Chronic Brain Stimulation Using Micro-Electrocortiographic Devices, Hayden C. Carney, Amelia A. Schendel, Justin Williams

The Journal of Purdue Undergraduate Research

No abstract provided.

Three-Dimensional Quantification Of Angiotensin Ii-Induced Abdominal Aortic Aneurysms Using High-Frequency Ultrasound, Amelia R. Adelsperger

The Journal of Purdue Undergraduate Research

No abstract provided.

Designing A Community-Based Water Harvesting System: Understanding Water Use In Endallah, Tanzania, Marisa Henry, Grace Baldwin, Garrett Quathamer

The Journal of Purdue Undergraduate Research

The World Health Organization (WHO) states it is a human right to have access to sufficient, safe water within one kilometer of the home (WHO, 2015b). However, 1.6 billion people experience economic water shortage and struggle to secure water for personal and domestic use (UN-Water & FAO, 2007). In the village of Endallah, Tanzania, seasonal rainfalls, high rates of evaporation, and inadequate water harvesting infrastructure leave many of the approximately 900 households facing economic water shortage. Around 90% of villagers depend on rainfed subsistence farming; however, annual crop yields are not consistent due to sporadic rainfall. The purpose of this …

Volume 39, Issue 1: Full Issue, Manuscripts Staff

Manuscripts

No abstract provided.

Clive Ragborn, Pop Singer, Bonnie Britton

Manuscripts

No abstract provided.

Large-Scale And High-Resolution 3-D Cave Mapping By Terrestrial Laser Scanning: A Case Study Of The Domica Cave, Slovakia, Michal Gallay, Ján Kaňuk, Zdenko Hochmuth, John D. Meneely, Jaroslav Hofierka, Vladimír Sedlák

International Journal of Speleology

Mapping and modelling the complicated geometry of caves is a challenging task that has traditionally been undertaken by tacheometric surveying methods. These methods are excellent for capturing the general shape of a cave system but they are not suitable for high-speed, high-resolution mapping of complex surfaces found in this environment. Terrestrial laser scanning (TLS) technologies can acquire millions of points represented by 3-D coordinates, at very high spatial densities on complex multifaceted surfaces within minutes. In the last few years, advances in measurement speed, reduction in size / cost and increased portability of this technology has revolutionised the collection of …

Quantitative Trait Loci Underlying Seed Sugars Content In “Md96-5722” By “Spencer” Recombinant Inbred Line Population Of Soybean, Masum Akond, David A. Lightfoot, My Abdelmajid Kassem, Khalid Meksem, Shiming Liu, Stella K. Kantartzi, Nacer Bellaloui

Articles

Sucrose, raffinose, and stachyose are important soluble sugars in soybean [Glycine max (L.) Merr.] seeds. Seed sucrose is a desirable trait for taste and flavor. Raffinose and stachyose are undesirable in diets of monogastric animals, acting as anti-nutritional factors that cause flatulence and abdominal discomfort. Therefore, reducing raffinose and stachyose biosynthesis is considered as a key quality trait goal in soy food and feed industries. The objective of this study was to identify genomic regions containing quantitative trait loci (QTL) controlling sucrose, raffinose, and stachyose in a set of 92 F5:7 recombinant inbred lines (RILs) derived from a cross between …

Exploring The Role Of Mkk7 In Excitotoxicity And Cerebral Ischemia: A Novel Pharmacological Strategy Against Brain Injury, A Vercelli, S Biggi, A Sclip, I E. Repetto, S Cimini, F Falleroni, S Tomasi, R Monti, N Tonna, F Morelli, V Grande, M Stravalaci, E Biasini, O Marin, F Bianco, D Di Marino, T Borsello

Publications and Research

Excitotoxicity following cerebral ischemia elicits a molecular cascade, which leads to neuronal death. c-Jun-N-terminal kinase (JNK) has a key role in excitotoxic cell death. We have previously shown that JNK inhibition by a specific cell-permeable peptide significantly reduces infarct size and neuronal death in an in vivo model of cerebral ischemia. However, systemic inhibition of JNK may have detrimental side effects, owing to blockade of its physiological function. Here we designed a new inhibitor peptide (growth arrest and DNA damage-inducible 45β (GADD45β-I)) targeting mitogen-activated protein kinase kinase 7 (MKK7), an upstream activator of JNK, which exclusively mediates JNK's pathological activation. …

Two New Cave-Dwelling Species Of The Millipede Genus Paracortina Wang & Zhang, 1993 From Southern China (Diplopoda, Callipodida, Paracortinidae), Weixin Liu, Mingyi Tian

KIP Articles

Two new species of the millipede genus Paracortina Wang & Zhang, 1993 are described. Both are presumed troglophiles: P. zhangi sp. n. from a cave in Ceheng County, southwestern Guizhou Province and P. yinae sp. n. from a cave in Longlin County, western Guangxi Zhuang Autonomous Region. A distribution map and a key to all 12 Paracortina species are also provided.

High-Throughput Screening Of Patient-Derived Cultures Reveals Potential For Precision Medicine In Glioblastoma, Christine E. Quartararo, Eduard Reznik, Ana C. De Carvalho, Tom Mikkelsen, Brent R. Stockwell

Neurosurgery Articles

Identifying drugs for the treatment of glioblastoma (GBM), a rapidly fatal disease, has been challenging. Most screening efforts have been conducted with immortalized cell lines grown with fetal bovine serum, which have little relevance to the genomic features found in GBM patients. Patient-derived neurosphere cultures, while being more physiologically relevant, are difficult to screen and therefore are only used to test a few drug candidates after initial screening efforts. Laminin has been used to generate two-dimensional cell lines from patient tumors, preserving the genomic signature and alleviating some screening hurdles. We present here the first side-by-side comparison of inhibitor sensitivity …

How Incorporating Physical Activity And Movement Into The Kindergarten Curriculum Will Help To Keep Students Engaged And Increase Their Academic Success, Katie M. Lockrem

School of Education and Leadership Student Capstone Theses and Dissertations

The research and curriculum writing that was done for this capstone answers the question of how incorporating physical activity and movement into the kindergarten will help to keep students engaged and increase their academic success. The current epidemic of childhood obesity and the push for all students to perform better on standardized tests lead to this capstone question. This capstone explores different ways to incorporate movement into the classroom to help students get the recommended sixty minutes of physical activity a day all while improving learning. It also explores other areas such as nutrition, breakfast in the classroom and different …

Deep Sequencing Of The Mexican Avocado Transcriptome, An Ancient Angiosperm With A High Content Of Fatty Acids, Enrique Ibarra-Laclette, Alfonso Méndez-Bravo, Claudia Anahí Pérez-Torres, Victor A. Albert, Keithanne Mockaitis, Aruna Kilaru, Rodolfo López-Gómez, Jacob Israel Cervantes-Luevano, Luis Herrera-Estrella

ETSU Faculty Works

Background: Avocado (Persea americana) is an economically important tropical fruit considered to be a good source of fatty acids. Despite its importance, the molecular and cellular characterization of biochemical and developmental processes in avocado is limited due to the lack of transcriptome and genomic information.

Results: The transcriptomes of seeds, roots, stems, leaves, aerial buds and flowers were determined using different sequencing platforms. Additionally, the transcriptomes of three different stages of fruit ripening (pre-climacteric, climacteric and post-climacteric) were also analyzed. The analysis of the RNAseqatlas presented here reveals strong differences in gene expression patterns between different organs, …

Bobolink (Dolichonyx Oryzivorus), Stephen G. Martin, Thomas A. Gavin, Rosalind Renfrew, Allan M. Strong, Noah G. Perlut

Environmental Studies Faculty Publications

Bobolink (Dolichonyx oryzivorus)
Order:PASSERIFORMES
Family: ICTERIDAE

Includes the following information: Introduction, Appearance, Systematics, Distribution, Migration and Habitat, Diet and Foraging, Sounds and Vocal Behavior, Behavior, Breeding, Demography and Populations, Conservation and Management, Priorities for Future Research, Acknowledgments, About the Author(s), Multimedia, Tables and Appendices, References

Disguising A Military Object As A Civilian Object: Prohibited Perfidy Or Permissible Ruse Of War?, Kevin Jon Heller

International Law Studies

A number of scholars have claimed that it is inherently perfidious to kill an enemy soldier by disguising a military object as a civilian object. This essay disagrees, noting that conventional and customary IHL deem at least five military practices that involve making a military object appear to be a civilian object permissible ruses of war, not prohibited acts of perfidy: camouflage, ambush, cover, booby-traps, and landmines. The essay thus argues that attackers are free to disguise a military object as a civilian object as long as the civilian object in question does not receive special protection under international humanitarian …

Presenting Evolution In Public Schools; Is It Indisputable?, Paul Andrew Erdman

School of Education and Leadership Student Capstone Theses and Dissertations

The research question addressed is, how do 10 public school teachers present the theory of evolution? The motivation of this capstone was my experience with teachers presenting evolution (all life having evolved from a simple single celled organism) to students as indisputable, and the seemingly lack of discussion about any problems with the theory or unanswered questions. A key influence was an older sibling, a mechanical engineer, who often provides scientific answers for me and provided many resources that challenge the so-called indisputability and possibilities of evolution. This study interviewed 10 public school teachers to identify how they present the …

The Use Of One-To-One Ipad Technology And Its Impact On Students Receiving Special Education Services Work Completion And Grades, Angela Jean Brumbaugh

School of Education and Leadership Student Capstone Theses and Dissertations

The research question addressed in this project was, how does the use of one-to-one iPad technology impact students who receive special education services grades and work completion? It examines and compares the work completion rates and grades of students receiving special education services in the general education setting, both before and after the implementation of the one-to-one iPad initiative. This mixed methods study examines fifteen secondary students’ grades in English, mathematics and social studies the trimester before the iPads introduction and follows the students for the full school year after the introduction to compare their grades and work completion rates. …

Achievement In Mathematics And Self-Concept Among Gifted Female High School Seniors, Leah M. Battin

School of Education and Leadership Student Capstone Theses and Dissertations

The author sought to explore the research question, What is the relationship between mathematics achievement and self-concept of gifted female high school seniors? Review of the literature included discussions of definitions and stereotypes of giftedness, gender differences in math/STEM attitudes and achievement, malleable versus fixed intelligence and ability in math, self-concept, and stereotype threat. The author worked with gifted female high school students at a summer camp for gifted students in South Dakota. Participants were recruited from the group of young women who had finished the camp in 2014. Of 20 young women contacted, five returned letters of consent. A …

X-Ray Structure Of A Mammalian Stearoyl-Coa Desaturase, Yonghong Bai, Jason G. Mccoy, Elena J. Levin, Pablo Sobrado, Kanagalaghatta R. Rajashankar, Brian G. Fox, Ming Zhou

Chemistry Faculty Research & Creative Works

Stearoyl-CoA desaturase (SCD) is conserved in all eukaryotes and introduces the first double bond into saturated fatty acyl-CoAs. Because the monounsaturated products of SCD are key precursors of membrane phospholipids, cholesterol esters and triglycerides, SCD is pivotal in fatty acid metabolism. Humans have two SCD homologues (SCD1 and SCD5), while mice have four (SCD1-SCD4). SCD1-deficient mice do not become obese or diabetic when fed a high-fat diet because of improved lipid metabolic profiles and insulin sensitivity^5,6. Thus, SCD1 is a pharmacological target in the treatment of obesity, diabetes and other metabolic diseases⁷. SCD1 is an integral …

The Murray Ledger And Times, August 13, 2015, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Initial Results Of The First Nsf-Funded Research Experience For Undergraduates On Small Satellite Software, Jeremy Straub, Ronald Marsh, David Whalen

Small Satellite Conference

This paper presents preliminary results from the first year of the first National Science Foundation (NSF) funded research experience for undergraduates (REU) with a focus on small satellite software. It begins with a discussion of prior work on the development of an open-hardware, open-source software CubeSat, the OpenOrbiter project and the Open Prototype for Educational NanoSats design, and how this served as foundational work for the REU. A brief discussion of the evaluation techniques used in this program is presented as are the results (which serve as a point of reference for which to compare those from the REU). Next, …

April Miller Et Al. Vs. Kim Davis (Date Filed August 12, 2015), United States District Court For The Eastern District Of Kentucky

Media Collection

APRIL MILLER, et al., PLAINTIFFS vs. KIM DAVIS, individually and in her official capacity, et al., DEFENDANTS CIVIL ACTION NO. 15-44-DLB UNITED STATES DISTRICT COURT FOR THE EASTERN DISTRICT OF KENTUCKY, NORTHERN DIVISION 2015 U.S. Dist. LEXIS 105822 August 12, 2015, Decided August 12, 2015, Filed.

April Miller Et Al. Vs. Kim Davis (Date Filled August 12, 2015), United States District Court For The Eastern District Of Kentucky

Media Collection

CIVIL ACTION NO. 15-44-DLB APRIL MILLER, et al. PLAINTIFFS vs. MEMORANDUM OPINION AND ORDER KIM DAVIS, individually and in her official capacity, et al. DEFENDANTS

2015 Fall Convocation Program, Office Of Communications & Marketing, Morehead State University.

Communications and Marketing Publications Archive

Fall convocation program held on August 12, 2015.

An Analysis Of Overstory Tree Canopy Cover In Sites Occupied By Native And Introduced Cottontails In The Northeastern United States With Recommendations For Habitat Management For New England Cottontail, Bill Buffum, Thomas J. Mcgreevy Jr., Amy E. Gottfried, Mary E. Sullivan, Thomas P. Husband

Natural Resources Science Faculty Publications

The New England cottontail (Sylvilagus transitionalis) is a high conservation priority in the Northeastern United States and has been listed as a candidate species under the Endangered Species Act. Loss of early successional habitat is the most common explanation for the decline of the species, which is considered to require habitat with dense low vegetation and limited overstory tree canopy. Federal and state wildlife agencies actively encourage landowners to create this habitat type by clearcutting blocks of forest. However, there are recent indications that the species also occupies sites with moderate overstory tree canopy cover. This is important …

Testing Factors Influencing Identification Rates Of Similar Species During Abundance Surveys, Anne Louise Schaefer, Paul Lukacs, Michelle L. Kissling

Wildlife Biology Faculty Publications

Most abundance estimation methods assume that all sampled individuals are identified correctly. In practice, this assumption may be difficult to meet and can bias abundance estimates, especially when morphologically similar species overlap in range. Over the past 2 decades, Kittlitz's Murrelet (Brachyramphus brevirostris) populations appear to have declined across parts of their Alaskan range, where they co-occur with the Marbled Murrelet (B. marmoratus). Recently, the reliability of Kittlitz's Murrelet declines have been questioned due to variability and uncertainty in species identification between the 2 species. We conduced a field experiment to quantify misidentification and partial identification …

Parameter Determination And Experimental Validation Of A Wire Feed Additive Manufacturing Model, Kannan Suresh Kumar, Todd E. Sparks, Frank W. Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Laser metal deposition with wire feed is one of the additive manufacturing methods with great scope and robustness. Process parameters plays an important role in controlling the process and obtaining an ideal manufactured part. Simulations tools are highly essential in determining the ideal parameters and melt pool conditions. The current work is a transient 3D model of wire feed additive manufacturing which realizes the heat transfer and fluid flow behavior of the process with varying laser power and power density. The model was programmed in Python and a 1 KW Gaussian beam fiber laser was used to conduct experiments. The …

Large Wildlife Removal Drives Immune Defence Increases In Rodents, Hillary S. Young, Rodolfo Dirzo, Kristofer M. Helgen, Douglas J. Mccauley, Charles L. Nunn, Paul Snyder, Kari E. Veblen, Serena Zhao, Vanessa O. Ezenwa

Wildland Resources Faculty Publications

1. Anthropogenic disturbances involving land use change, climate disruption, pollution and invasive species have been shown to impact immune function of wild animals. These immune changes have direct impacts on the fitness of impacted animals and, also, potentially indirect effects on other species and on ecological processes, notably involving the spread of infectious disease. Here, we investigate whether the selective loss of large wildlife can also drive changes in immune function of other consumer species.
2. Using a long-standing large-scale exclosure experiment in East Africa, we investigated the effects of selective removal of large wildlife on multiple measures of immune function in …

Dynamic Characteristics Of Biologically Inspired Hair Receptors For Unmanned Aerial Vehicles, Manohar Chidurala

LSU New Orleans Theses and Dissertations

The highly optimized performance of nature’s creations and biological assemblies has inspired the development of their engineered counter parts that can potentially outperform conventional systems. In particular, bat wings are populated with air flow hair receptors which feedback the information about airflow over their surfaces for enhanced stability and maneuverability during their flight. The hairs in the bat wing membrane play a role in the maneuverability tasks, especially during low-speed flight. The developments of artificial hair sensors (AHS) are inspired by biological hair cells in aerodynamic feedback control designs. Current mathematical models for hair receptors are limited by strict simplifying …

"Trifles Of Value": Craft As Communication In Victorian Literature, Amanda C. Larson

Master's Theses and Doctoral Dissertations

This thesis argues that craft functions in the nineteenth century as a form of communication that expresses female identity in Elizabeth Gaskell's Cranford and Margaret Oliphant's Miss Marjoribanks. By looking at the novels through the lens of Talia Schaffer's craft paradigm in connection with Thing theory, it is possible to make connections between the role of craft and identity, which in turn raises questions about craft and female agency. These connections to female agency illuminate tensions between craft and the economy, gender disparity in the arts, and the limitations of class. In order to explore these notions it is …