Digital Commons Network^™

Using Computer-Aided Design Software And 3d Printers To Improve Spatial Visualization, Petros Katsioloudis, Millie Jones

STEMPS Faculty Publications

Many articles have been published on the use of 3D printing technology. From prefabricated homes and outdoor structures to human organs, 3D printing technology has found a niche in many fields, but especially education. The education of technology and engineering students has come a long way from traditional instruction using hand drawings. Although drawings may still be a part of a students learning, computer technology has been embraced in this field for several years. With the introduction of AutoCAD technical drawing programs and now 3D printing, learners can use 3D printed models to develop their spatial abilities in technology and …

Unfair And Deceptive Robots, Woodrow Hartzog

Faculty Scholarship

Robots, like household helpers, personal digital assistants, automated cars, and personal drones are or will soon be available to consumers. These robots raise common consumer protection issues, such as fraud, privacy, data security, and risks to health, physical safety and finances. Robots also raise new consumer protection issues, or at least call into question how existing consumer protection regimes might be applied to such emerging technologies. Yet it is unclear which legal regimes should govern these robots and what consumer protection rules for robots should look like.

The thesis of the Article is that the FTC’s grant of authority and …

Media: Mean Distance Association And Its Applications In Nonlinear Gene Set Analysis., Hesen Peng, Junjie Ma, Yun Bai, Jianwei Lu, Tianwei Yu

PCOM Scholarly Works

Probabilistic association discovery aims at identifying the association between random vectors, regardless of number of variables involved or linear/nonlinear functional forms. Recently, applications in high-dimensional data have generated rising interest in probabilistic association discovery. We developed a framework based on functions on the observation graph, named MeDiA (Mean Distance Association). We generalize its property to a group of functions on the observation graph. The group of functions encapsulates major existing methods in association discovery, e.g. mutual information and Brownian Covariance, and can be expanded to more complicated forms. We conducted numerical comparison of the statistical power of related methods under …

A Coxiella-Like Endosymbiont Is A Potential Vitamin Source For The Lone Star Tick, Todd A. Smith, Timothy Driscoll, Joseph J. Gillespie, Rahul Raghavan

Biology Faculty Publications and Presentations

Amblyomma americanum (Lone star tick) is an important disease vector in the United States. It transmits several human pathogens, including the agents of human monocytic ehrlichiosis, tularemia, and southern tick-associated rash illness. Blood-feeding insects (Class Insecta) depend on bacterial endosymbionts to provide vitamins and cofactors that are scarce in blood. It is unclear how this deficiency is compensated in ticks (Class Arachnida) that feed exclusively on mammalian blood. A bacterium related to Coxiella burnetii, the agent of human Q fever, has been observed previously within cells of A. americanum. Eliminating this bacterium (CLEAA, Coxiella-like endosymbiont of A. americanum) with antibiotics …

An Exploration Of The Wheel-Induced Feeding-Suppression, Stephen Benjamin Peckham

Theses and Dissertations (Comprehensive)

Anorexia nervosa is an enigmatic human condition typified by food-restriction that is often accompanied by extensive exercise. This has been modeled in rats in the wheel-induced feeding-suppression (WIFS) model. In this model, animals are given access to a running-wheel, which induces a volitional drop in food-consumption. Short periods of wheel access have induced a feeding-suppression which is effectively reversed by chlorpromazine administration (Adams et al., 2009). Recent attempts at replicating Adams et al.’s (2009) feeding-suppression have, however, been unsuccessful (Peckham et al., 2013). These attempts raised questions as to whether or not the existing methodology is most effective at suppressing …

Characterization Of The Trans-Plasma Membrane Electron Transport System In The Myelin Membrane, Afshan Sohail

Theses and Dissertations (Comprehensive)

Myelination is the key feature of evolution in the nervous system of vertebrates. Myelin is the protrusion of glial cells. More specifically, "oligodendrocytes" in the central nervous system (CNS), and "Schwann" cells in the peripheral nervous system (PNS) form myelin membranes. Myelin remarkably, enhances the propagation of nerve impulses. However, myelin restricts the access of extracellular metabolites to the axons. A pathology called "demyelination" is associated with myelin. The myelin sheath is not only an insulator, but it is itself metabolically active. In this study it is hypothesized that the ratio of NAD(P)⁺/NAD(P)H and the glycolytic pathway of …

The Spirit Of Haudenosaunee Youth: The Transformation Of Identity And Well-Being Through Culture-Based Activism, Bonnie M. Freeman

Theses and Dissertations (Comprehensive)

This dissertation examines the connection between Indigenous knowledge and culture-based action, and how this connection facilitates a sense of identity and well-being for Haudenosaunee youth. This study examines the experience of fourteen Haudenosaunee youth and five parents/adults as they ran for four summers (2005-2008) on a youth-led spiritual journey known as the Unity Run. On this journey youth travelled throughout Haudenosaunee traditional territory (Ontario and Quebec, Canada; and New York State, U.S.A.) and beyond (Virginia, North Carolina, Tennessee) carrying a message of peace, unity and social justice.

The methodology of this research is framed within Haudenosaunee traditional protocols (visiting and …

The Effects Of Lampricide 3-Trifluoromethyl-4-Nitrophenol Toxicity On The Gills Of Larval Sea Lamprey And Non-Target Rainbow Trout And Lake Sturgeon, Lisa A. Sorensen

Theses and Dissertations (Comprehensive)

The pesticide, 3-trifluoromethyl-4-nitrophenol (TFM), is widely used in the Great Lakes to control invasive sea lampreys (Petromyzon marinus) populations, but much about its sub-lethal effects remains unknown. A better understanding of its toxicity is needed to improve TFM effectiveness and to protect non-target organisms from its potential adverse effects. The objectives of this thesis were to test the following two hypotheses: (1) impairment of mitochondrial ATP production by TFM interferes with ATP-dependent ion-uptake by fish, leading to altered electrolyte balance, and (2) perturbations of gill function by TFM are exacerbated in soft, ion poor water (SW; 40 mg …

Influence Of Planning Resources On Gait Control In Parkinson’S Disease, Frederico P. Faria

Theses and Dissertations (Comprehensive)

Movement disturbances in individuals with Parkinson’s disease (PD) have been associated with difficulties to plan complex actions. Performance of simple and complex actions overloads resources for individuals with Parkinson’s disease (PD). However, it is unclear if central resources required to plan gait adjustments while walking exacerbate gait disturbances of patients with PD. More specifically, it is unclear how gait impairments, sensory processing, and the dopaminergic system influence the load on processing resources (e.g. cognitive load) during the planning of step modifications. In order to investigate the relative influence of these factors on cognitive load and its impact on gait control, …

‘Water Is Life’: Exploring The Relationship Between Place Identity, Water And Adaptive Capacity In Fort Resolution, Northwest Territories, Canada, Jennifer A. Fresque-Baxter

Theses and Dissertations (Comprehensive)

Water is recognised as a fundamental human right in Canada’s Northwest Territories (NWT). However, the current and potential effects of climate change coupled with resource development pressures are leading to concerns about maintaining the health and viability of freshwater in the NWT. These intersecting multiple exposures can have far-reaching impacts for NWT residents who rely on water for cultural, spiritual, economic and social purposes. Ongoing changes (e.g., to water quantity, water quality, weather, precipitation and ice dynamics, for example) will increasingly require NWT residents to adapt, seek ways to plan for the future, identify opportunities, and moderate the effects of …

The Christian Farmers Federation Of Ontario: Integrating Christian Principles With The Practicality Of Farming, Suzanne M. Armstrong

Theses and Dissertations (Comprehensive)

This thesis examines the Christian identity and characteristics of the Christian Farmers Federation of Ontario (CFFO), a general farm organization active in the diverse agricultural sector of Ontario, Canada. It highlights the intersection of religion and farming that emerged from interviews and participant observation within this group. The thesis probes what it means for them to be responsible Christian farmers in contemporary agriculture. Christian and secular scholars from three key areas of scholarship—Dutch immigration to Canada, agriculture of the middle or family farming, and Christian stewardship—help to contextualize their responses.

The CFFO was founded as a Dutch neo-Calvinist organization within …

Estimates Of Persistent Inward Current In Human Motor Neurons During Postural Sway, Ryan Foley, Jayne M. Kalmar Dr.

Theses and Dissertations (Comprehensive)

Persistent inward current (PIC) is a membrane property critical for increasing gain of motor neuron output. In humans, most estimates of PIC are made from plantarflexor or dorsiflexor motor units with the participant in a seated position with the knee flexed. This seated and static posture neglects the task-dependent nature of the monoaminergic drive that modulates PIC activation. Seated estimates may drastically underestimate the amount of PIC that occurs in human motor neurons during functional movement. The current study estimated PIC using the conventional paired motor unit technique which uses the difference between reference unit firing frequency at test unit …

Connecting To Others: Studying The Relationship Between Social Exclusion And Imitation, Sarah K. Blyth

Theses and Dissertations (Comprehensive)

Automatic imitation (AI) refers to the subconscious tendency we have to imitate an observed action, even when that action is irrelevant to or interferes with an action we are attempting to execute (Heyes, 2011; Brass et al., 2000). Human beings display a fundamental need to stay meaningfully connected to others, also known as the need to belong. Previous research shows that an experience of rejection can reduce one’s feelings of connectedness to others (Legate et al., 2013), and that behaviours such as non-conscious mimicry (NCM) increase after being excluded as a possible means of re-affiliation (Lakin et al., 2008). It …

Affective Migration: The Role Of Food Preparation And Visceral Experience For Egyptian Migrant Women Settling In The Region Of Waterloo, Mary Neil

Theses and Dissertations (Comprehensive)

This study examining Egyptian migrants settling in Canada is exploratory in nature and is intended to initiate a conversation about the personal experience of transnationalism and the value of the body as an instrument of research. A semi-structured interview approach was designed to prompt the evocation of deep personal thoughts, experiences, and sensations in response to questions surrounding migration to Canada through the shared performative act of cooking and the visceral experience of eating in the private space of the migrant kitchen. Using a grounded theory approach, several adaptive mechanisms were identified such as the creation of manageable daily routines, …

Perceptions Of Determining Factors: A Case Study Of Eviction Risks Of People Who Hoard In Waterloo Region, Emily J. Gibson

Theses and Dissertations (Comprehensive)

Recently distinguished as a distinct disorder in the DSM-V, hoarding remains a behaviour about which we have only a cursory understanding. Hoarding behaviours can lead to a variety of health and safety risks, not only for the person who hoards, but for others who live with them, and their neighbouring community. Many studies make reference to the vulnerability of people who hoard as a result of these health and safety risks However, there has been little written about eviction specifically due to hoarding. This study explores the research question: what factors enable individuals who hoard to maintain their housing when …

The Development And Application Of A Measure To Assess The Interpersonal Qualities Of Self-Talk, Elizabeth L. Price

Theses and Dissertations (Comprehensive)

In three studies, this research describes the development and potential application of a new self-report measure, the Interpersonal Self-Talk Scale (IPSTS). Based on Kiesler’s (1983) Interpersonal Circle: Acts Version, and the Revised Interpersonal Adjective Scales (IAS-R; Wiggins et al., 1988) the IPSTS was designed to measure the distinct interpersonal qualities of self-talk. In Study 1 (N = 316), a principal components analysis of the IPSTS items yielded two underlying dimensions of dominance and affiliation. The preliminary octant subscales displayed good internal consistency reliability and circumplex structure, and the IPSTS was shown to measure a construct that is reasonably …

Purification And Characterization Of Bcsc; An Integral Component Of Bacterial Cellulose Export, Emily D. Wilson Ms

Theses and Dissertations (Comprehensive)

Biofilms are a growing concern in the medical field due to their increased resistance to antibiotics. When found in a biofilm, bacteria can have antibiotic resistance 10-1000 times that of their planktonic counterparts. Therefore, it is important to study the formation of biofilms. Cellulose biofilms are formed by Enterobacteriaceae, such as many Escherichia coli and Salmonella spp. strains. Biofilms provide these species with benefits including antimicrobial protection, development of bacterial communities, promotion of DNA exchange, uptake of nutrients, and, in the case of cellulose biofilms, immune system evasion. Cellulose biofilms are controlled by the Bacterial cellulose synthesis (Bcs) complex located …

Parental Spatial Input During Parent-Child Interactions: A Two-Dimensional Versus A Three-Dimensional Learning Experience, Ariel Ho

Theses and Dissertations (Comprehensive)

Children’s spatial ability is predictive of their future achievement in many academic and occupational domains, including science, technology, engineering, and mathematics (STEM; e.g., Wai at el., 2009). During the early years, experiences such as hearing spatial language (e.g., Ferrara et al., 2011) and engaging in spatial activities with three-dimensional (3D) blocks or puzzles (e.g., Casey et al., 2008) are found to facilitate children’s spatial learning. Other than 3D toys, the use of two-dimensional (2D) touchscreen media (e.g., iPads^®) by young children has been on the rise (e.g., Rideout, 2013). Technology has become part of children’s daily activities and …

Enhancing Canadian Girls’ Resilience Through Girls-Only Programming, Ayesha Umme-Jihad

Theses and Dissertations (Comprehensive)

Canadian girls face a number of complex issues as they transition through girlhood and into adolescence. Despite the barriers they face, girls can be resilient with the development of internal and external assets. Presently, we know that protective factors developed in girls-only programs between the critical ages of 9 and 13 enhance girls’ resilience in the short-term (Alcade, Hayward, Loomis, & Hodgson, 2012). This thesis project operationalizes protective factors as confidence, critical thinking skills, connectedness, and parental relationships. Risk factors are operationalized as adversity within environments, depression, negative behaviours, and substance use. A mixed methods approach is used to investigate …

The Disability Cliff, Samuel R. Bagenstos

Articles

We’re pretty good about caring for our disabled citizens—as long as they’re children. It’s time to put equal thought into their adulthoods.

Children’S Health In A Legal Framework, Clare Huntington, Elizabeth S. Scott

Faculty Scholarship

The interdisciplinary periodical Future of Children has dedicated an issue to children’s health policy. This contribution to the issue maps the legal landscape influencing policy choices. The authors demonstrate that in the U.S. legal system, parents have robust rights, grounded in the Constitution, to make decisions concerning their children’s health and medical treatment. Following from its commitment to parental rights, the system typically assumes the interests of parents and children are aligned, even when that assumption seems questionable. Thus, for example, parents who would limit their children’s access to health care on the basis of the parents’ religious belief have …

Disappearing Legal Black Holes And Converging Domains: Changing Individual Rights Protection In National Security And Foreign Affairs, Andrew Kent

Faculty Scholarship

This Essay attempts to describe what is distinctive about the way the protection of individual rights in the areas of national security and foreign affairs has been occurring in recent decades. Historically, the right to protection under the U.S. Constitution and courts has been sharply limited by categorical distinctions based on geography, war, and, to some extent, citizenship. These categorical rules carved out domains where the courts and Constitution provided protections and those where they did not. The institutional design and operating rules of the national security state tracked these formal, categorical rules about the boundaries of protection. There have …

Dynamic Ocean Management: Defining And Conceptualizing Real-Time Management Of The Ocean, Sara M. Maxwell, Elliot L. Hazen, Rebecca L. Lewison, Danial C. Dunn, Helen Bailey, Steven J. Bograd, Dana K. Briscoe, Sabrina Fossette, Alistair J. Hobday, Meredith Bennett

Biological Sciences Faculty Publications

Most spatial marine management techniques (e.g., marine protected areas) draw stationary boundaries around often mobile marine features, animals, or resource users. While these approaches can work for relatively stationary marine resources, to be most effective marine management must be as fluid in space and time as the resources and users we aim to manage. Instead, a shift towards dynamic ocean management is suggested, defined as management that rapidly changes in space and time in response to changes in the ocean and its users through the integration of near real-time biological, oceanographic, social and/or economic data. Dynamic management can refine the …

Books Reviews & Books Recieved, Moe Moe Nyunt, Benson Goh, R. David Rightmire, Christoph Raedel, Joel Thomas Chopp, Taylor S. Brown, Isaiah Allen, Timothy J. Christian, Benjamin D. Espinoza, Jonathan E. Beck, Brian Shockey, Andrew D. Kinsey, Moe Moe Nyunt, Taylor Zimmerman

The Asbury Journal

No abstract provided.

Casitas: A Location-Dependent Ecological Trap For Juvenile Caribbean Spiny Lobsters, Panulirus Argus, Benjamin C. Gutzler, Mark J. Butler Iv, Donald C. Behringer

Biological Sciences Faculty Publications

Casitas are artificial shelters used by fishers to aggregate Caribbean spiny lobsters (Panulirus argus) for ease of capture. However, casitas may function as an ecological trap for juvenile lobsters if they are attracted to casitas and their growth or mortality is poorer compared with natural shelters. We hypothesized that juvenile lobsters may be at particular risk if attracted to casitas because they are less able than larger individuals to defend themselves, and do not forage far from shelter. We compared the nutritional condition, relative mortality, and activity of lobsters of various sizes in casitas and natural shelters in adult and …

Altered Connexin 43 Expression Underlies Age-Dependent Decrease Of Regulatory T Cell Suppressor Function In Nonobese Diabetic Mice, Michel Kuczma, Cong-Yi Wang, Leszek Ignatowicz, Robert Gourdi, Piotr Kraj

Biological Sciences Faculty Publications

Type 1 diabetes is one of the most extensively studied autoimmune diseases, but the cellular and molecular mechanisms leading to T cell–mediated destruction of insulin-producing β cells are still not well understood. In this study, we show that regulatory T cells (T_regs) in NOD mice undergo age-dependent loss of suppressor functions exacerbated by the decreased ability of activated effector T cells to upregulate Foxp3 and generate T_regs in the peripheral organs. This age-dependent loss is associated with reduced intercellular communication mediated by gap junctions, which is caused by impaired upregulation and decreased expression of connexin 43. Regulatory …

Mutations In The Plasmodium Falciparum Chloroquine Resistance Transporter, Pfcrt, Enlarge The Parasite's Food Vacuole And Alter Drug Sensitivities, Serena Pulcini, Henry M. Staines, Andrew H. Lee, Sarah H. Shafik, Guillaume Bouyer, Catherine M. Moore, Daniel A. Daley, Matthew J. Hoke, Lindsey M. Altenhofen, Heather J. Painter, Jainbing Mu, David J.P. Ferguson, Manuel Llinás, Rowena E. Martin, David A. Fidock, Roland A. Cooper, Sanjeev Krishna

Biological Sciences Faculty Publications

Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, are the major determinant of chloroquine resistance in this lethal human malaria parasite. Here, we describe P. falciparum lines subjected to selection by amantadine or blasticidin that carry PfCRT mutations (C101F or L272F), causing the development of enlarged food vacuoles. These parasites also have increased sensitivity to chloroquine and some other quinoline antimalarials, but exhibit no or minimal change in sensitivity to artemisinins, when compared with parental strains. A transgenic parasite line expressing the L272F variant of PfCRT confirmed this increased chloroquine sensitivity and enlarged food vacuole phenotype. Furthermore, the introduction …

Las Casas Remembered:The 500th Anniversary Of The Struggle For The Human Rights Of The Native Peoples Of America, David M. Traboulay

Publications and Research

At first a part of the colonial system as an encomendero, he later dedicated his life to the struggle for justice and human rights of the indigenous peoples of America. At the grand debate of 1551 between Dr. Sepulveda and Las Casas, Las Casas presented a very modern view of human rights that is one of the useful models of human rights for the contemporary world.

Litigation Isolationism, Pamela K. Bookman

Faculty Scholarship

Over the past two decades, U.S. courts have pursued a studied avoidance of transnational litigation. The resulting litigation isolationism appears to be driven by courts’ desire to promote separation of powers, international comity, and the interests of defendants. This Article demonstrates, however, that this new kind of “avoidance” in fact frequently undermines not only these values but also other significant U.S. interests by continuing to interfere with foreign relations and driving plaintiffs to sue in foreign courts.

This Article offers four contributions: First, it focuses the conversation about transnational litigation on those doctrines designed to avoid it—that is, doctrines that …

Vincentian Heritage 32:2

Vincentian Studies

No abstract provided.