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2014

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Analysis And Design Of Thermal Management System For Thermoelectric Generators For Nuclear Power Plant Safety, Chih-Chieh Lin Dec 2014

Analysis And Design Of Thermal Management System For Thermoelectric Generators For Nuclear Power Plant Safety, Chih-Chieh Lin

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

This project aims to develop thermoelectric generators (TEG)-based devices for sensing during normal and off-normal conditions in Small Modular Reactors (SMRs). Locations such as reactor core vessels, steam generators, housings of pumps, heat exchangers, and steam pipe housings in primary loop and secondary loop are potential installation sites. The heat is conducted through an adaptor to the TEGs and removed by a heat sink by means of natural convection. The electrical power generated by the TEGs is then used to drive sensors and wireless communications. Additional power can be stored in batteries or in super capacitors for emergency operations. The …

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Expression, Purification, And Characterization Of The Short Isoform Of Adenylosuccinate Lyase, Benjamin Rajan Dec 2014

Expression, Purification, And Characterization Of The Short Isoform Of Adenylosuccinate Lyase, Benjamin Rajan

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Cells require purines for critical biological processes that can be created by the de novo biosynthetic pathway or maintained by the salvage pathways. The de novo pathway in humans requires 6 enzymes, some of which are multifunctional. Adenylosuccinate lyase (ASL) catalyzes step 8 of the de novo pathway converting susuccinylaminoimidazolecarboxamide ribonucleotide (SAICAR) to aminoimidazolecarboxamide ribotide (AICAR). It also catalyzes the second step of the purine nucleotide cycle by converting SAMP to AMP. A short isoform of ASL (sASL) is ubiquitously expressed in all cell types at a lower concentration. This shortened splice variant does not perform catalysis on either of …

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The Versatile Applications Of 6-Alkynyl Fucose And Other Fucose Analogs In Studying Protein Fucosylation, Esam Al-Shareffi Dec 2014

The Versatile Applications Of 6-Alkynyl Fucose And Other Fucose Analogs In Studying Protein Fucosylation, Esam Al-Shareffi

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Glycosylation is the modification of a target molecule with carbohydrate. It is a common and complex co- or post-translational protein modification that is responsible for diverse and essential biological roles including cellular communication, modulation of function, and the provision of specific ligands for carbohydrate-binding proteins. Fucosylation is a specific type of glycosylation that results from the transfer of fucose, a unique monosaccharide with the L-configuration, to its target proteins or glycans through the action of fucosyltransferases. Thirteen fucosyltransferases have been identified, including protein O-fucosyltransferases 1 and 2 (POFUT1 and POFUT2), responsible for addition of fucose to the hydroxyl group of …

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Development Of A Line-Scanned Dual-Axis Confocal Microscope For Video-Rate Diagnostic Imaging, Danni Wang Dec 2014

Development Of A Line-Scanned Dual-Axis Confocal Microscope For Video-Rate Diagnostic Imaging, Danni Wang

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

The prevalence of oral cancer has been increasing at an alarming rate in recent years. Due to a limited understanding of the cause and progression of this disease, patient prognosis remain poor, and the mortality and morbidity of the disease remain significant. The need to diagnose cancerous regions early is key to patient survival. However, the high cost and invasive nature of standard pathological analysis motivates the search for an alternative real-time imaging technology that provides accurate non-invasive early diagnosis of the disease. The goal of this thesis is to develop a line-scanned dual-axis confocal (LS-DAC) microscope for high-resolution, high-contrast, …

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Transition Metal Borates As Cathode Materials For Rechargeable Batteries, Shou-Hang Bo Dec 2014

Transition Metal Borates As Cathode Materials For Rechargeable Batteries, Shou-Hang Bo

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

High-capacity rechargeable batteries play a central role in a variety of emerging technologies, including mobile electronics, plug-in and hybrid electric vehicles, and grid-scale storage. All of these technologies will greatly benefit from the design and discovery of next-generation cathode materials that can deliver substantially higher energy densities at reduced cost. Transition metal borates are promising cathode candidates for battery applications, since the mass/charge ratio (m/z) of borate group (BO33-) is the lowest among all common polyanion groups. A variety of borate based compounds were therefore explored as potential Li-ion and Mg-ion battery cathodes in this dissertation Comprehensive studies were carried …

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The Influence Of Drought On The Ecological And Evolutionary Genomics Of Fungal Pathogenesis In An Annual Plant, Brassica Rapa, Niamh Breda O'Hara Dec 2014

The Influence Of Drought On The Ecological And Evolutionary Genomics Of Fungal Pathogenesis In An Annual Plant, Brassica Rapa, Niamh Breda O'Hara

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

There is growing evidence that populations are evolving rapidly in response to climate change. However, the potential cost associated with adapting, and the genetic basis of both rapid evolution and costs of adaptation remain largely unexplored. With climate change, drought is increasing in frequency and severity, widely affecting plant yield and fitness in agricultural and natural populations. For my dissertation, I integrated multiple approaches (field, greenhouse, lab and bioinformatic) to explore the ecological and evolutionary effects of drought on an agriculturally important plant-pathogen system: the annual herbaceous plant Brassica rapa (field mustard), and its fungal pathogen Alternaria brassicae. In a …

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Distributed Estimation In The Presence Of Correlation, Zhiyuan Weng Dec 2014

Distributed Estimation In The Presence Of Correlation, Zhiyuan Weng

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

We study the problem of distributed estimation, where a group of nodes are required to cooperate with each other to estimate some parameter of interest from noisy measurements without a fusion center. Distributed estimation algorithms are useful in several areas, including wireless sensor networks, where robustness, scalability, flexibility, and low power consumption are desirable. In this dissertation, we mainly focus on the cases where the node measurements are correlated. First, we consider the problem of fusing multiple estimates from different nodes. Cases of both known and unknown correlation are investigated. A Bayesian approach and a convex optimization approach are proposed. …

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The Effects Of Cpg And Upa Dinucleotides On The Attenuation Of Poliovirus By Codon Pair Deoptimization, Malka Arabov Dec 2014

The Effects Of Cpg And Upa Dinucleotides On The Attenuation Of Poliovirus By Codon Pair Deoptimization, Malka Arabov

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Codon pair bias, the preferential pairing of certain codons over others, has been observed in all species analyzed ranging from bacteria to mammals. Previous research has shown that artificial coupling of underrepresented codon pairs (codon pair deoptimization) in viral genomes (such as poliovirus and influenza virus) reduces gene function and leads to virus death or attenuation. Although the reason for this phenomenon is unclear, increasing underrepresented codon pairs in an RNA viral coding region consequently increases the frequency of CpG and UpA dinucleotides. These dinucleotides are suppressed in a variety of species and may be responsible for attenuation by codon …

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The Adenovirus L4-22k Protein Serves As The Master Regulator To Coordinate Late Gene Expression And Viral Dna Packaging, Diana Guimet Dec 2014

The Adenovirus L4-22k Protein Serves As The Master Regulator To Coordinate Late Gene Expression And Viral Dna Packaging, Diana Guimet

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

The adenovirus L4-22K protein is multifunctional and critical for different aspects of viral infection. Following DNA replication, increasing amounts of the L4-22K protein are observed prior to the appearance of other late viral proteins. We found that L4-22K controls viral gene expression at the post-transcriptional level and regulates the accumulation of the L4-33K protein, another critical viral regulator, at the level of alternative pre-mRNA splicing. This initiates an activation cascade of late viral proteins, while early genes are being turned off. To gain a better understanding of the mechanism of action of L4-22K, we sought to map the critical elements …

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Questionable Form: An Inquiry Into The Relationship Between Philosophy And Literature, Amir Rauf Alduha Jaima Dec 2014

Questionable Form: An Inquiry Into The Relationship Between Philosophy And Literature, Amir Rauf Alduha Jaima

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Through a comparative reading of philosophical and literary texts, I examine the distinction between the projects and practices of philosophy and literature. I argue that, like philosophy, novels make arguments and explicitly engage the range of philosophical questions; and like literature, essential elements of philosophy include aesthetic considerations. Moreover, the presumed distinction between philosophy and literature does a disservice to both. If we overlook the literary qualities of philosophy, we risk relegating to the margins important contributions to traditional philosophical problems; and if we overlook the philosophical qualities of literature, we risk passing over some of the most profound elements …

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Attachment's Role In Social Support And Mentoring: An Investigation Among Collegiate Women, Alberto Herrera-Alcazar Dec 2014

Attachment's Role In Social Support And Mentoring: An Investigation Among Collegiate Women, Alberto Herrera-Alcazar

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Recent years have seen a concerted effort to increase the number of women pursuing Science, Technology, Engineering and Mathematics (STEM) fields. Although one approach to retention of undergraduates in STEM fields has been formal mentoring programs, other channels, such as naturally occurring mentor relationships, have served to retain students in science and other disciplines as well. The current project investigated the interplay between attachment representations of close relationships, social support and mentor relationships. The first aim was to examine the relationship between attachment and general facets of social support. The second aim was to assess benefits of mentor relationships on …

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Shape-Based Analysis, Krishna Chaitanya Gurijala Dec 2014

Shape-Based Analysis, Krishna Chaitanya Gurijala

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Shape analysis plays a critical role in many fields, especially in medical analysis. There has been substantial research performed for shape analysis in manifolds. On the contrary, shape-based analysis has not received much attention for volumetric data. It is not feasible to directly extend the successful manifold shape analysis methods, such as heat diffusion, to volumes due to the huge computational cost. The work presented herein seeks to address this problem by presenting two approaches for shape analysis in volumes that not only capture the shape information efficiently but also reduce the computational time drastically. The first approach is a …

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Understanding Online Fashion Networks, Kota Yamaguchi Dec 2014

Understanding Online Fashion Networks, Kota Yamaguchi

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Emergence of online social networks has transformed how people interact with digital media. Any user is a consumer and a publisher of media content, such as texts, images, or videos, in the online community. In such an environment, it is crucial to develop technology to help people by organizing and utilizing plethora of media content to meet the community demands. To this goal, this dissertation studies and tries to establish computational approaches to understand networked content, using large-scale data from a real-world online fashion network, Chictopia. This study focuses on two major challenges of fashion networks: understanding of visual content, …

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University Of Dayton Magazine, Winter 2014-15, University Of Dayton Magazine Dec 2014

University Of Dayton Magazine, Winter 2014-15, University Of Dayton Magazine

University of Dayton Alumni Publications

This issue includes information about work UD students are doing in Africa, stories long told on campus, and the death penalty.

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October To December 2014 Dec 2014

October To December 2014

All Summaries

No abstract provided.

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The Impact Sex Trafficking Education Has On Reported Cases, Ivette Cervantes Dec 2014

The Impact Sex Trafficking Education Has On Reported Cases, Ivette Cervantes

2014 Fall Honors Capstone Projects - Archive

The purpose of this research study was to determine whether educating the public on the issue of sex trafficking has an impact on cases being reported. Several non-profit organizations located across Texas were interviewed. The organizations' mission is to provide services to sex trafficking victims and raise public awareness. Interviews were conducted with organizations located in Dallas, Fort Worth, Austin, and Houston. A major finding is that failure to properly identify victims is a core issue. Public awareness has increased. The public is aware that sex trafficking is a current issue, but their awareness does not impact cases being reported. …

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Numerical And Experimental Investigation Of Variable Transportation Cooling For Reusable Thermal Protection Systems, Stefano Gulli Dec 2014

Numerical And Experimental Investigation Of Variable Transportation Cooling For Reusable Thermal Protection Systems, Stefano Gulli

Mechanical and Aerospace Engineering Dissertations - Archive

This research work is focused on the numerical and experimental investigation of the transpiration cooling technique for reusable thermal protection systems. The transpiration cooling has been considered because of its higher cooling effectiveness, with respect to other active cooling techniques, in terms of minimum amount of coolant to be used and minimum interference to the external flow. An innovative approach based on the coupling of the hypersonic boundary layer with the thermal response of porous materials is used to numerically study the thermal management potential of the transpiration cooling technique. The new concept of the variable transpiration is introduced by …

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An Ic Design For Wireless Batteryless Multi-Sensing Platform For Biomedical Applications, Young-Sik Seo Dec 2014

An Ic Design For Wireless Batteryless Multi-Sensing Platform For Biomedical Applications, Young-Sik Seo

Electrical Engineering Dissertations - Archive

This work proposed an integrated circuit (IC) design that provides the required functionality for a wireless, batteryless implant. For biomedical applications, the physiological signals can be detected if the parameter of interest can be converted to a change in electrical parameters such as capacitance, resistance or an amperometric signal. The implantable transponder is suitable for sensors that generate one of the aforementioned analog signals. In the proposed universal platform, a voltage-controlled oscillator (VCO) was used to detect variations of voltage or current. Similarly, a relaxation oscillator (RO) was used to detect changes in capacitance or resistance. Thus, the VCO and …

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Installments, University Of Texas At Arlington Library Dec 2014

Installments, University Of Texas At Arlington Library

Installments

A marketing periodical installed on the back of bathroom stall doors.

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Temperature-Dependence Of Stress-Related Phenomena, Rahmat Saptono Dec 2014

Temperature-Dependence Of Stress-Related Phenomena, Rahmat Saptono

Material Science and Engineering Dissertations - Archive

Efforts have been made to develop a simple but physically sound model. The model was specifically proposed to capture, explain, and estimate the temperature sensitivity and strengthening mechanism phenomena in small volume material with particular reference to the roles grain boundary and surface. Model-inspired phenomenology approach was applied to reveal the key mechanisms and find directions for a more complete constitutive model. The model was developed in the limited space where diffusion is insignificant. It was assumed that the plastic flow was predominantly governed by the thermally-activated process of dislocation glide overcoming barriers. Simple mathematical functions were formulated and evaluated …

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Experimental And Numerical Study Of Phase Transition Of Lifepo₄ Material In Lithium Ion Batteries, Md Noor E Alam Siddique Dec 2014

Experimental And Numerical Study Of Phase Transition Of Lifepo₄ Material In Lithium Ion Batteries, Md Noor E Alam Siddique

Material Science and Engineering Dissertations - Archive

Phase transition behavior of LiFePO4 material has been studied in this work. During electrochemical charge/discharge processes, LiFePO4 transforms into FePO4 and this electrochemically driven phase transition of the two-phase system results in a potential plateau in a battery discharge curve. Besides, battery performance, especially under high rates, depends critically on this two-phase transition. However, this phase transition mechanism in the LiFePO4 crystal structure has yet not been understood in details. Developing better understanding is essential for designing high performing, safe and stable batteries.Currently available phase transition models for LiFePO4, such as the classical `core-shrinking model' and recently the `domino cascade …

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A Qualitative Analysis Of Mentoring Experiences And Perceptions Of Female Students Enrolled In A Doctoral Program In Education At A Midwestern University, Sherrill Rayford Dec 2014

A Qualitative Analysis Of Mentoring Experiences And Perceptions Of Female Students Enrolled In A Doctoral Program In Education At A Midwestern University, Sherrill Rayford

Dissertations

This qualitative study analyzed mentoring experiences and perceptions of females enrolled in a doctorate program of education, including a Principal Investigator-led peer mentoring group. The snowball technique generated 20 participants who were interviewed for a two-part study to share mentoring experiences by responding to Research Question One: What are the mentoring experiences of a sample of female students enrolled in an Educational leadership doctoral program at a Midwestern University? The conceptual framework explored experiences and perceptions of women at the doctoral level, mentoring support systems, and barriers to doctoral completion. Additional interviews were sought from faculty named as providing mentoring …

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Classroom Amplification: The Necessity Of Sound-Amplification In The Classroom, Kalley Ellis Dec 2014

Classroom Amplification: The Necessity Of Sound-Amplification In The Classroom, Kalley Ellis

Undergraduate Honors Capstone Projects

In a classroom, the optimal signal-to-noise ratio, as is recommended by the American Nation Standards Institute (ANSI), is 35 dBA, with the reverberation reaching a maximum of 0.6s (Lewis, 2008); yet, in classrooms today, the typical signal-to-noise ratio ranges from 40-73 dBA (Lewis, 2008). With at least 75% of the school day being spent in listening activities (e.g. reading, instructions, lecture, etc.), this noise level in the classroom has great impact on what a child hears and, thus, learns (Blazer, 2008). Unfortunately, with each new year, classroom sizes are increasing and creating an even more detrimental noise level and signal-to-noise …

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Reforming The Performance Of Masculinity: Stephen Crane's Critiques Of Riis's And Roosevelt's Civic Militarism, Cambri Mcdonald Spear Dec 2014

Reforming The Performance Of Masculinity: Stephen Crane's Critiques Of Riis's And Roosevelt's Civic Militarism, Cambri Mcdonald Spear

Undergraduate Honors Capstone Projects

The Progressive Era (1890-1920) marks a unique period of social change in American history not only because of reformists' muckraking attacks against political machines and other corrupt social practices, but also because gender permeated every aspect of reform. The doctrine of separate spheres, which had been such a mainstay of Industrial Revolution-era America, was blurring rapidly, as many reformists, like suffragists, pressed for greater gender equality. However, an extremely fascinating characteristic of this period that is often overlooked is the inevitable way in which the performance of gender became essential for reformists to be successful.

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Targeted Drug Delivery System For Kidney And/Or Liver Failure Patients Using Human Serum Albumin, Sean Bedingfield Dec 2014

Targeted Drug Delivery System For Kidney And/Or Liver Failure Patients Using Human Serum Albumin, Sean Bedingfield

Undergraduate Honors Capstone Projects

Compromised liver and/or kidney function reduces the acceptable dosage of a variety of medications that can be administered to patients. These patients still have a need for drugs such as nonsteroidal anti-inflammatory drugs (NSAIDs), antivirals, and antibiotics. The project goal is to provide a drug delivery system to accommodate these reduced dosage limits with added therapeutic benefits to address symptoms of liver or kidney failure. Localized drug delivery allows for a smaller, concentrated dose rather than inundating the patient's system with the drug of interest. Human serum albumin (HSA) is a researched candidate for drug delivery with therapeutic properties. HSA …

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The Effect Of Functional Fixation In Problem Solving Among Preschool, Second Grade, And Ninth Grade Children, Michael Kenneth Nehring Dec 2014

The Effect Of Functional Fixation In Problem Solving Among Preschool, Second Grade, And Ninth Grade Children, Michael Kenneth Nehring

Dissertations

Functional fixedness is a cognitive function whereby an individual becomes fixated on a given function of an object, which prevents the individual from using the object in an alternative fashion to solve a problem (Duncker, 1935/1945). The current study analyzed the effect of functional fixedness on 36 children from three different age groups, preschool, second grade, and ninth grade. The children were presented with a problem solving activity based on a problem used by German and Defeyter (2000), in which they concluded that young children are immune to the effects of functional fixedness. Research conducted by Chrysikou (2006) indicated using …

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Aminooxy Reagents In Nanomedicine And Bioanalysis., Stephanie Mattingly Dec 2014

Aminooxy Reagents In Nanomedicine And Bioanalysis., Stephanie Mattingly

Electronic Theses and Dissertations

The development of nanomaterials as medical diagnostic and therapeutic agents is a rapidly expanding field. A brief search of the literature revealed that roughly half of all articles related to nanoparticle-based drug delivery were published after the onset of this thesis research, over the past 4 years. A few nano-based formulations have entered into clinical use, including liposomal drug formulations, protein-linked drugs, and nanoparticle-based MRI contrast agents. The chemistry that enables conjugation of a functional cargo, whether a drug, a targeting element, or a radionucleotide, to a nanocarrier is thus a critical component for development. Oximation is one of the …

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Triggered Release Of Small Molecules From Solid Supports Using Heat Or An Applied Magnetic Field., Ralph Jacob Knipp Dec 2014

Triggered Release Of Small Molecules From Solid Supports Using Heat Or An Applied Magnetic Field., Ralph Jacob Knipp

Electronic Theses and Dissertations

The reaction of an aminooxy moiety (RONH2) with an aldehyde or ketone carbonyl, an oximation reaction, results in the formation of robust oxime ether linkages. Oximation is a form of click chemistry and is chemoselective, occurs in a variety of solvents including water, and produces high yields with little to no purification. We were inspired to exploit the advantages of oximation reactions by attaching aminooxy-functionalized molecules to solid supports, thus allowing us to employ aminooxy chemistry in ways that cannot be achieved using solution phase. Chapter 1 provides a review of aminooxy chemistry, its advantages over similar reactions and its …

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Fabrication Of A Thin Silver Nanowire Composite Film And Investigation Of A Patterning Technique., Richard S. Korte 1991- Dec 2014

Fabrication Of A Thin Silver Nanowire Composite Film And Investigation Of A Patterning Technique., Richard S. Korte 1991-

Electronic Theses and Dissertations

Electrically conductive polymers encompass an exciting field of research for applications in dye-sensitized solar cells (DSSC’s). DSSC’s possess several advantages over other types of solar cells. They offer the potential for high quantum efficiency, solar conversion efficiency approaching that of traditional silicon panels, rapid charge transfer kinetics for photo-excited electrons, mechanical flexibility, and cost efficient manufacturing processes. However, key drawbacks to their large scale production and performance lifetime lie in their reliance on costly indium tin oxide (ITO), fluorinated tin oxide (FTO), and platinum for electrode materials, and the mechanical fragility inherent to a liquid electrolyte layer component. Much of …

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The National Science Foundation's Coupling, Energetics And Dynamics Of Atmospheric Regions (Cedar) Student Community, Leda Sox, Timothy Duly, Barbara Emery Dec 2014

The National Science Foundation's Coupling, Energetics And Dynamics Of Atmospheric Regions (Cedar) Student Community, Leda Sox, Timothy Duly, Barbara Emery

Physics Student Research

The National Science Foundation sponsors Coupling, Energetics, and Dynamics of Atmospheric Regions (CEDAR) Workshops, which have been held every summer, for the past 27 years. CEDAR Workshops are on the order of a week long and at various locations that are close to university campuses where CEDAR type scientific research is done. Although there is no formal student group within the CEDAR community, the workshops are very student-focused. Roughly half the Workshop participants are students. There are two Student Representatives on the CEDAR Science Steering Committee (CSSC), the group of scientists who organize the CEDAR Workshops. Each Student Representative is …

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