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2014

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Fresh Pursuit: A Survey Of Law Among States With Large Land Based Tribes, Erin E. White Dec 2014

Fresh Pursuit: A Survey Of Law Among States With Large Land Based Tribes, Erin E. White

American Indian Law Journal

No abstract provided.


Beyond Blood Quantum: The Legal And Political Implications Of Expanding Tribal Enrollment, Tommy Miller Dec 2014

Beyond Blood Quantum: The Legal And Political Implications Of Expanding Tribal Enrollment, Tommy Miller

American Indian Law Journal

No abstract provided.


Aicpa Code Of Professional Conduct Effective December 15, 2014, Unless Early Implemented. Updated For All Official Releases Through December 15, 2014, American Institute Of Certified Public Accountants (Aicpa) Dec 2014

Aicpa Code Of Professional Conduct Effective December 15, 2014, Unless Early Implemented. Updated For All Official Releases Through December 15, 2014, American Institute Of Certified Public Accountants (Aicpa)

AICPA Professional Standards

No abstract provided.


Periodontal Microorganisms, Obesity, Chronic Inflammation, And Type 1 Diabetes, Georges Joseph Nahhas Dec 2014

Periodontal Microorganisms, Obesity, Chronic Inflammation, And Type 1 Diabetes, Georges Joseph Nahhas

Theses and Dissertations

Periodontal disease is a low-grade chronic inflammation in the tissues surrounding the teeth caused by multiple, mostly gram-negative pathogens. It is associated with diabetes, obesity, and chronic inflammation. The specific roles that periodontal microorganism play in these conditions are not well-studied. Hereby, we explored how periodontal bacteria from sub gingival plaque clustered in youth with and without type 1 diabetes, and how such patterns related to body-mass-index percentile (BMI percentile), C-reactive protein (CRP) and adiponectin. Cross-sectional data were collected from 105 youth with type 1 diabetes and 71 without diabetes. Participants were between 12 and 19 years of age receiving …


Exploration Of Implicit Bias On Multidisciplinary Team Members When Referring African American Students For Special Education Services, Twana Romona Fletcher Dec 2014

Exploration Of Implicit Bias On Multidisciplinary Team Members When Referring African American Students For Special Education Services, Twana Romona Fletcher

Theses and Dissertations

The disproportionality or overrepresentation of African American students in special education is a longstanding problem that continues to be prevalent today. There are numerous reasons why this phenomenon continues to persist including but not limited to implicit bias among multidisciplinary team members (MDT). One function of the MDT is to decide if a student needs to be referred for special education services. Therefore, the purpose of this study was to examine the decision making processes of the MDT members to determine if implicit bias impacted their decision to refer an African American student for special education services. This qualitative study …


Determining The Change Styles Preferences Of Principals In South Carolina's Secondary Schools With A Background In The Fine Arts, Sterling Bernard Harris Dec 2014

Determining The Change Styles Preferences Of Principals In South Carolina's Secondary Schools With A Background In The Fine Arts, Sterling Bernard Harris

Theses and Dissertations

Very little research has been published regarding the change style preferences and leadership styles of secondary principals in South Carolina who have a common background. The purpose of this mixed methods study was to identify the preferred change style preference of principals in South Carolina that have an arts background and the change style preferences of principals without an arts background. This study would also determine if these styles were the same or different. Quantitative data were gathered from online administration of the Change Style Indicator (CSI), the South Carolina Department of Education, and the South Carolina Association of School …


Impacts Of Adolescents' Emotional And Behavioral Concerns And Social Skills On Parenting Stress, Marissa Miller Dec 2014

Impacts Of Adolescents' Emotional And Behavioral Concerns And Social Skills On Parenting Stress, Marissa Miller

Theses and Dissertations

Minimal literature has examined predictors of parenting stress for parents of adolescents and what may contribute to the impact of these predictors, particularly those regarding adolescent behavior. The current study sought to evaluate whether adolescents’ internalizing and externalizing behaviors significantly predicted parenting stress and whether adolescent social skills moderated the relationship. Covariates of gender, age, ethnicity, and socioeconomic status were entered first into a multiple regression moderation model and followed by internalizing and externalizing behaviors, social skills, and interaction terms, respectively. The overall model explained 19 percent of the variance in parenting stress. While internalizing behaviors significantly predicted parenting stress, …


Life Satisfaction And Academic Performance In Early Adolescents: Evidence For Reciprocal Relationships, Zi Jia Ng Dec 2014

Life Satisfaction And Academic Performance In Early Adolescents: Evidence For Reciprocal Relationships, Zi Jia Ng

Theses and Dissertations

Student well-being remains a relatively neglected topic despite its intimate link to positive school outcomes. As academic achievement is the yardstick of student success and school accountability, school-based mental health research and practice have focused primarily on the assessment and treatment of learning and behavioral problems. This shortterm longitudinal study sought to establish the role of student subjective well-being in academic achievement. Based on the engine model of well-being (Jayawickreme, Forgeard, & Seligman, 2012), the study focused on life satisfaction as a process variable and academic performance as an outcome variable. Using two waves (five months apart) of data, the …


The Roles Of Gsk-3ss And Apc In Cytoplasmic Dynein Regulation, Feng Gao Dec 2014

The Roles Of Gsk-3ss And Apc In Cytoplasmic Dynein Regulation, Feng Gao

Theses and Dissertations

Dynein is a microtubule minus-end directed molecular motor, participating in a broad range of cellular functions, such as organelle transport, cell migration and mitosis. Dynein dysfunction is linked to many diseases including ALS, schizophrenia, Alzheimer’s disease, Parkinson’s disease and cancer. The mechanism of dynein regulation is largely unknown. We have provided evidence that glycogen synthase kinase 3β (GSK-3β) directly regulates dynein in both neurons and non-neuronal cells. GSK-3β interacts with and phosphorylates dynein in vitro. Dynein phosphorylation by GSK-3β reduces its interaction with Ndel1, a regulator contributing to dynein force generation. Dynein motility is stimulated both by pharmacological GSK-3β inhibitors …


Mcp-1 In Colorectal Cancer: Benefits Of Exercise, Jamie Lee Mcclellan Dec 2014

Mcp-1 In Colorectal Cancer: Benefits Of Exercise, Jamie Lee Mcclellan

Theses and Dissertations

The etiology of colon cancer is a complex phenomenon that involves both genetic and environmental factors. However, only about 20% have a familial basis with the largest fraction being attributed to environmental causes that can lead to chronic inflammation. Tumors associated macrophages drive the pro-inflammatory response in the tumor micro-environment and are associated with poor prognosis in certain cancers. Monocyte chemoattractant protein 1 (MCP-1) is thought to be the most important chemokine for recruitment of macrophages to the tumor microenvironment. In chapter 1, we examined the timing and magnitude of the intestinal inflammatory cytokine response in relation to tumorigenesis in …


The Geologic Implications Of The Factors That Affected Relative Sea-Level Positions In South Carolina During The Pleistocene And The Associated Preserved High-Stand Deposits, William Richardson Doar Iii Dec 2014

The Geologic Implications Of The Factors That Affected Relative Sea-Level Positions In South Carolina During The Pleistocene And The Associated Preserved High-Stand Deposits, William Richardson Doar Iii

Theses and Dissertations

This work utilizes the current understanding of South Carolina geology to provide a stratigraphic review of the late-Pliocene and Pleistocene marine deposits. Almost two centuries of recorded geological study includes geomorphic and stratigraphic units that were described, proposed, revised, abandoned, and revived. Along with the history of the age assignments, changes in geological time scales, and the changes in the understanding of geological concepts, this review is necessary because two concurrent and conflicting stratigraphies exist for late-Pliocene and Pleistocene marine sediments that record multiple sea-level transgressions that were more often destructive than constructive. The result, when tested against existing geological …


Toward The Combinatorial Development Of Hydrophobic-Tagged Antifolate-Directed Degradation Of Human Thymidylate Synthase, Daniel J. Menasco Dec 2014

Toward The Combinatorial Development Of Hydrophobic-Tagged Antifolate-Directed Degradation Of Human Thymidylate Synthase, Daniel J. Menasco

Theses and Dissertations

Direct post-translational control over a protein of interest (POI) can be exploited by manipulating the cells protein quality-control systems responsible for either intracellular turnover through ubiquitination (POI half-life) or repairing and degrading misfolded proteins.1 In an effort to target and degrade a high value POI we selected the enzyme human thymidylate synthase (TS) for post-translational degradation through ligand-directed ubiquitination and hydrophobic tagging. Thymidylate synthase catalyzes the reductive methylation of 2’-deoxyuridine monophosphate (dUMP) to 2’-deoxythymidine monophosphate (dTMP). As the de novo source of dTMP the regulation of intracellular TS is strictly controlled by ubiquitinindependent proteasomal degradation mediated by an internal TS-degron …


Design And Development Of A Novel Class Of Cell Cycle Cdk Inhibitors Targeting The Cyclin Binding Groove Utilizing The Replace Strategy, Padmavathy Nandha Premnath Dec 2014

Design And Development Of A Novel Class Of Cell Cycle Cdk Inhibitors Targeting The Cyclin Binding Groove Utilizing The Replace Strategy, Padmavathy Nandha Premnath

Theses and Dissertations

Inhibition of CDK2 activity in G1 and S phases of the cell cycle can promote selective apoptosis of cancer cells through the E2F1 pathway. Currently available CDK inhibitors target the ATP binding pocket and result in lack of specificity for the cell cycle vs. the transcriptional CDKs. It has been shown that a peptide HAKRRLIF derived from the tumor suppressor p21 binds to the cyclin binding groove (CBG) and selectively inhibits cell cycle CDKs (CDK2/Cyclin A, CDK2/Cyclin E and CDK4/Cyclin D). The CBG is unique to cell cycle CDKs hence targeting this site avoids the inhibition of transcriptional CDKs can …


Defining And Supporting Organizational Readiness In The Interactive Systems Framework For Dissemination And Implementaion, Jonathan Peter Scaccia Dec 2014

Defining And Supporting Organizational Readiness In The Interactive Systems Framework For Dissemination And Implementaion, Jonathan Peter Scaccia

Theses and Dissertations

Introduction. In the implementation literature, organizational readiness is associated with an increased likelihood of achieving innovation outcomes. Organizational readiness consists of organizational capacity (general and innovation-specific) and organization motivation. Organizations who wish to get results from their innovations have an interest in making sure that certain factors and subcomponents are in place. However, having awareness that certain capacities and factors that influence motivation are linked to improved innovation outcomes does not necessarily help organizations to get “more ready.” There is a need for organizations to know if and how they can effectively put these factors and subcomponents into place. This …


Analysis Of Hurricane Preparedness Levels And Evacuation Intent For South Carolina Coastal Residents, Wesley Chad Seigler Dec 2014

Analysis Of Hurricane Preparedness Levels And Evacuation Intent For South Carolina Coastal Residents, Wesley Chad Seigler

Theses and Dissertations

Many communities across the nation, especially those in coastal areas, are experiencing extensive growth and expansion. This growth and the associated need for additional infrastructure, goods and services, and basic human needs often place people and the things they value in harm’s way due to the threat of a natural disaster. In order to properly prepare and mitigate disaster impacts, individuals and communities must view disasters as events that will likely occur at least once during their lifetime rather than simply outside possibilities. Residents of coastal communities must prepare for potential impacts from hurricanes and resulting storm surges and must …


Early Screening And Identification Of Preschool Children Affected By Serious Emotional Disorders, Cathy Renee Robey-Williams Dec 2014

Early Screening And Identification Of Preschool Children Affected By Serious Emotional Disorders, Cathy Renee Robey-Williams

Theses and Dissertations

Mental illness has surpassed physical health problems as the leading cause for morbidity and mortality in American children. National prevalence of serious emotional disorders in the 0-5 age group has ranged from 9.5% to 14.2%. Of the 15 million children affected by mental illness, less than 20- 25% receive any treatment. Nationwide, early screening, identification, and treatment of preschoolers with emotional or behavioral disorders have become a critical priority in order to reduce the increasing burden of healthcare costs for mental illness and psychiatric care. The purpose of this study was to test the feasibility of a screening process for …


Leadership Perspectives On International Education For Public School Students In South Carolina: Two Case Studies, Frederick Eugene Brown Dec 2014

Leadership Perspectives On International Education For Public School Students In South Carolina: Two Case Studies, Frederick Eugene Brown

Theses and Dissertations

This study explores how two rural public school districts in South Carolina conceptualize and implement an international education, according to the perspectives of administrators and teachers. This comparative case study of two public school districts spans the districts’ elementary, middle, high and career center schools and seeks to understand how the presence of a major multinational corporation influences school internationalization. The data on their perspectives on internationalization were drawn from interviews. I interviewed the school principal and teachers involved in internationalizing the curriculum, policy and practice in each of the ten schools. In addition to school level personnel, I interviewed …


Low Reynolds Number Turbulence: Mechanisms And Applications, Wei Zhao Dec 2014

Low Reynolds Number Turbulence: Mechanisms And Applications, Wei Zhao

Theses and Dissertations

Turbulence, as one of "the most important unsolved classical problem in physics" (R. Feynman, 1932), has been investigated for more than 130 years. Conventionally, turbulence is believed to be a phenomenon of high Reynolds numbers (Re). However, we find that turbulence can also be achieved at low Re by proper external forcing, either in macroflows or in microflows. In macroflows, the characteristics of high Re turbulence can be achieved in confined flows, when the bulk flow Re is around 400, by external forcing at its optimal frequency (Wang 2003; Wang 2006). Interestingly, the optimal narrow band of frequency is fixed …


Gestational Weight Gain, Pregnancy Outcomes, And Use Of Perinatal Health Services, Lujing Zhan Dec 2014

Gestational Weight Gain, Pregnancy Outcomes, And Use Of Perinatal Health Services, Lujing Zhan

Theses and Dissertations

This dissertation consists of three studies that were undertaken to better understand 1) the role of gestational weight gain (GWG) during early pregnancy on subsequent blood pressure changes and the risk of pregnancy-induced hypertension (PIH), 2) the causal effect of GWG in both early and mid-late pregnancy on the subtypes of preterm births, and 3) the impact of personal capital on the use of perinatal health services (i.e., prenatal care use and preconception care counseling). The first two studies were based on the data from the 1988 National Maternal and Infant Health Survey and the third study employed the data …


Applications Of Advanced Imaging Methods: Macro-Scale Studies Of Woven Composites And Micro-Scale Measurements On Heated Ic Packages, Siming Guo Dec 2014

Applications Of Advanced Imaging Methods: Macro-Scale Studies Of Woven Composites And Micro-Scale Measurements On Heated Ic Packages, Siming Guo

Theses and Dissertations

As a representative advanced imaging technique, the digital image correlation (DIC) method has been well established and widely used for deformation measurements in experimental mechanics. This methodology, both 2D and 3D, provides qualitative and quantitative information regarding the specimen’s non-uniform deformation response. Its full-field capabilities and non-contacting approach are especially advantageous when applied to heterogeneous material systems such as fiber-reinforced composites and integrated chip (IC) packages. To increase understanding of damage evolution in advanced composite material systems, a series of large deflection bending-compression experiments and model predictions have been performed for a woven glass-epoxy composite material system. Stereo digital image …


Diversity, Genetics, And Health Benefits Of Sorghum Grain, Davina Rhodes Dec 2014

Diversity, Genetics, And Health Benefits Of Sorghum Grain, Davina Rhodes

Theses and Dissertations

Staple cereal crops provide the majority of nutrients to the world's population, and thus, can significantly impact human nutrition and health. Phenotypic and genetic diversity within a crop can be useful for biofortification and crop improvement, but quantitative phenotyping is needed to identify varieties with high or low concentrations of a nutrient of interest, and to identify alleles responsible for quantitative trait variation of the nutrient. Sorghum [Sorghum bicolor (L.) Moench] is a diverse and widely adapted cereal crop that provides food for more than 500 million people in sub-Saharan Africa and Asia, and is becoming increasingly popular in specialty …


Going Up The Country: A Comparison Of Elite Ceramic Consumption Patterns In Charleston And The Carolina Frontier, Rebecca E. Shepherd Dec 2014

Going Up The Country: A Comparison Of Elite Ceramic Consumption Patterns In Charleston And The Carolina Frontier, Rebecca E. Shepherd

Theses and Dissertations

The 18th century colonial world is characterized by a dramatic increase in the consumption of goods identified as the “consumer revolution.” During this period fashionable material culture and the social performances associated with their use became universally recognized symbols of group membership. This thesis uses archaeological evidence to explore variation in the degree of participation in the consumer revolution between urban and rural settings in late eighteenth-century South Carolina. The data used for this research will be taken from excavated ceramic assemblages of two domestic archaeological sites, both of which were homes owned consecutively by the wealthy Brewton and Motte …


A Phenomenological Study Of Student Engagement In United States History Classrooms, Emily Louvette Manigault Dec 2014

A Phenomenological Study Of Student Engagement In United States History Classrooms, Emily Louvette Manigault

Theses and Dissertations

The purpose of this phenomenological study is to explore the relationship between student engagement and the perception of academic achievement (learning) by teachers and students in an urban high school social studies course. Over the past several years, educational leaders and researchers have tried to find a cause for a number of issues in public education, including low academic achievement, increasing student drop-out rates and the decline of positive perceptions of schools in general. As a result, there has been increasing research done on the level of engagement that students experience during their schooling. Much of the research has focused …


The Influence Of Organizational Climate On The Use And Quality Of Evidence-Based Practices In School Mental Health, Katherine Knies Dec 2014

The Influence Of Organizational Climate On The Use And Quality Of Evidence-Based Practices In School Mental Health, Katherine Knies

Theses and Dissertations

Organizational climate is defined as the reflection of workers’ perceptions of, and emotional responses to, the characteristics of their work environment (Glisson & James, 2002). While previous research explored the importance of organization climate for the adoption of evidence-based practices (EBPs) in mental health settings, there is a dearth of organizational climate focused research in school mental health settings (SMH). The current study examines the influence of organizational climate on two separate dependent variables: the extent to which EBPs were used and the quality of clinician delivery for the evidence-based practices used in a quality improvement intervention for SMH practitioners. …


Experimental And Theoretical Studies Of Native And Engineered Vascular Tissue Mechanics, Boran Zhou Dec 2014

Experimental And Theoretical Studies Of Native And Engineered Vascular Tissue Mechanics, Boran Zhou

Theses and Dissertations

Background: Implantation of vascular grafts provides a means to restore blood flow in compromised regions of the circulatory system, and thus is used to treat a wide range of cardiovascular diseases. Despite significant advancements in autologous grafting strategies as well as the engineering of synthetic alternatives, mechanical, structural, and compositional incongruities between the graft and the host artery remain as contributing factors to graft failure. The typical failure modality manifests as proximal anastomotic intimal hyperplasia, which places restrictions on the host vessel size currently treated with grafting strategies (> 5 mm internal diameter). In order to improve long-term clinical outcomes, …


Bio-Active Degradable Micellar Hydrogels For Osteogenic Differentiation Of Mesenchymal Stem Cells, Seyedsina Moeinzadeh Dec 2014

Bio-Active Degradable Micellar Hydrogels For Osteogenic Differentiation Of Mesenchymal Stem Cells, Seyedsina Moeinzadeh

Theses and Dissertations

A feasible approach to the restoration of injured bone tissue is the use of tissue engineering strategies to deliver mesenchymal stem cells (MSCs) to the site of regenration in degradable, in-situ gelling, bio-active hydrogels. Although inert Polyethylene glycol (PEG) hydrogels provide flexibility in controlling the cell microenvironment, their use for in vivo applications in tissue regeneration is limited by their persistence (nondegradability) in the site of regeneration. In an attempt to produce inert hydrolytically degradable matrices for encapsulation of MSCs, hydrogels based on star PEG macromonomers chain-extended with short hydroxy acid (HA) segments (SPEXA) were synthesized and characterized with respect …


Compositional Traits In Sorghum Bicolor Characterized By Transcriptome, Ionome And Genome-Wide Association Analysis, Nadia Shakoor Dec 2014

Compositional Traits In Sorghum Bicolor Characterized By Transcriptome, Ionome And Genome-Wide Association Analysis, Nadia Shakoor

Theses and Dissertations

To address the challenge of global mineral malnutrition, current biofortification research in crop plants aims to improve mineral concentration and micronutrient bioavailablity via genetic and traditional breeding methods. Many staple food crops are also used as biofuels, and the chemical and mineral composition of these energy crops directly affect biomass quality and subsequent energy output. Identification of genes and QTL that impact mineral and compositional traits in the grain and biomass of major cereals, including sorghum, is fundamental to developing breeding and selection methods aimed at increasing bioavailable minerals and improving biofuel suitability and seed nutritional quality. A combinatorial strategy …


Theoretical Investigation Of The Catalytic, Liquid-Phase Hydrodeoxygenation Of Organic Acids And Esters, Sina Behtash Dec 2014

Theoretical Investigation Of The Catalytic, Liquid-Phase Hydrodeoxygenation Of Organic Acids And Esters, Sina Behtash

Theses and Dissertations

With worldwide fossil fuel resources dwindling and greenhouse gas emissions rising, it is urgent to find renewable liquid fuel alternatives from e.g. biomass to meet the world’s growing energy demand. Lipid feedstocks and pyrolysis oils from woody biomass can be utilized for the production of second-generation biofuels via a catalytic hydrodeoxygenation (HDO) process. The conversion of fatty acids and esters plays an important role in the activity and selectivity of these processes. Understanding the HDO reaction mechanism of organic acids and esters on metal surfaces is a prerequisite for the rational design of new HDO catalysts specifically designed for upgrading …


Essays On Battle Clusters In Internal Armed Conflicts And Insurgencies: Concept, Causes And Consequences, Chifeng Liu Dec 2014

Essays On Battle Clusters In Internal Armed Conflicts And Insurgencies: Concept, Causes And Consequences, Chifeng Liu

Theses and Dissertations

With the purpose to re-conceptualize the intensity of internal armed conflicts, I argue that the characteristics such as location, scale and duration of “major battlefields,” i.e. the spatio-temporal clusters of combat events are important in the evaluation of impact of modern civil wars and insurgencies. I start with elaborating and constructing a new concept of conflict magnitude with battle clusters using up-to-date geo-referenced data and spatial statistic methods. In the second article, I first explain the location and duration of major battlefields. The findings indicate that an area with multiple non-state armed groups (NSAGs) is more likely to become main …


Perception Of Police In Public Housing Communities, Taylor Brickley Dec 2014

Perception Of Police In Public Housing Communities, Taylor Brickley

Theses and Dissertations

Research on the relationship between police and citizens consistently finds that attitudes toward police (ATP) are least positive among black citizens in areas of concentrated disadvantage. While much of the research in this area focuses specifically on ATP among young black males in low-income communities because they have the most contact with police, there has been relatively little research that has included older and/or female residents. Additionally, research has yet to examine ATP in racial and economic enclaves that may have different social and environmental characteristics than the surrounding community. This study utilizes in-depth interviews with 60 residents of two …