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2014-May-09-2014 Alumni Awards, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Not All Seca Proteins Are Created Equal: A Study Of The Seca1 And Seca2 Proteins Of Mycobacterium Tuberculosis., Nadia G. D'Lima

Doctoral Dissertations

In bacteria, most secreted proteins are exported through the SecYEG translocon by the SecA ATPase motor via the general Sec pathway. The identification of an additional SecA protein, particularly in Gram-positive pathogens, has raised important questions about the role of SecA2 both in protein export and establishment of virulence. In Mycobacterium tuberculosis, the causative agent of Tuberculosis (TB), the accessory SecA2 protein possesses ATPase activity that is required for bacterial survival in host macrophages, highlighting its importance in virulence. This study probes the biochemical differences between the two SecA proteins in order to gain insight into how they interact with …

Computational Methods In Metabolomics, Mai Hamdalla

Doctoral Dissertations

Diverse health challenges such as rising incidence of metabolic disease, rapid aging, and increasing antibiotic resistance are facing current humanity. Most diseases involve many genes in complex interactions, as well as environmental influences that are often not well understood. High-throughput advances in genome sequencing, transcript measurement, and protein measurement have been developed to address these challenges. A number of disease biomarkers have been identified as a result of an increased understanding of cellular functions. The observation of such systems-level cellular behavior has naturally extended to the metabolite level, leading to the study of metabolomics. Measurement of the metabolites in a …

Implications Of Species-As-Individuals: Kinds, Essentialism, Induction, De-Extinction, Mark Lowe

Doctoral Dissertations

The individuality thesis, or “species-as-individuals” (SAI), is the dominant view in philosophy of biology. Biological species are not natural kinds, but individuals. This dissertation defends SAI against recent proposals to reconceptualize species as natural kinds. I argue that, despite criticisms, the preponderance of considerations still weighs in favor of SAI. I then defend another consensus view in philosophy of biology, that species have no essential intrinsic qualitative properties (species anti-essentialism), against recent attempts to revive essentialism, and show how SAI is better suited than the view that species are natural kinds to defeat essentialism. I next develop an account of …

Exploring The Factors That Influence And Motivate Female Students To Enroll And Persist In Collegiate Stem Degree Programs: A Mixed Methods Study, Rosemary L. Edzie

Department of Educational Administration: Dissertations, Theses, and Student Research

Nationally, the need for an increase in interest, enrollment, and degrees awarded from science, technology, engineering and mathematics (STEM) degree programs continues to suffer. While students are enrolling in collegiate STEM degree programs, it is not occurring at a rate that meets the workforce demand. In addition to the concern that there is not a sufficient amount of collegiate STEM majors, there is a concern over too few females enrolling and persisting in collegiate STEM degree programs.

This mixed methods sequential exploratory research study considered the factors that influence and motivate undergraduate female students to enroll and persist in collegiate …

Determining Forage Intake Of Nursing Calves Grazing Native Sandhills Rangeland, Jennifer A. Walker

Department of Animal Science: Dissertations, Theses, and Student Research

Effective management of grazing lands is important for longevity and productivity. Accurate calculations of stocking rates per animal unit will aid in long term sustainability. Calculating stocking rates for cattle can prove challenging for cows and nursing calves. Limited research has been conducted to determine forage intake of the nursing calf pre-weaning. The objective of Trial 1 was to determine nursing calf forage intake over time until weaning. Trial 1 used 8 crossbred cow-calf pairs in experiment 1 and 12 pairs in experiment 2. Pairs were separated into two groups rotating between grazing upland range or housed in individual pens …

Chemical Profiling And Biological Activity Of Two Tunicate-Associated Marine Bacteria, Lyubina Yankova

Honors Scholar Theses

Marine natural products have recently been an increasingly abundant source of novel antibiotics. Given that there is an increasing resistance to current drug therapies, finding new sources such as marine natural products is essential. Tunicate-associated marine bacteria can be a significant source of antibacterial compounds. Two tunicates of the species Eudistoma were collected from Portobelo National Park on the Salmedina Reef of Panama in the Caribbean Sea. Bacteria associated with the tunicate were isolated, cultured, extracted, and fractionated. Fractions were tested against an array of clinically relevant bacterial pathogens in the BioMAP assay. Two fractions MB0086E and MB0088E demonstrated activity …

The Echo: May 9, 2014, Taylor University

2013-2014 (Volume 101)

Open doors, open to threats – Out loud at Last – Top five news events of the week – Correction – Online teasers – Dodging dark financial days – Building the Breuninger bayou – In The Loop – Around The World – Missing girls, missing rescue – Hilarious Headlines – “Hey Brandkamp, why are YOU wearing that shirt?” DC Recipe of the week – Echograms #TaylorU -- #TaylorU’s Top Tweets – A very tangled web – A semester of Adoration – The illuminating sounds of Lucius – The sexual pluralist revolution: reasons to be skeptical – Blurred lines – Weekly …

Correlates Of Gang Involvement And Health-Related Factors Among African American Females With A Detention History, Dexter R. Voisin

Faculty Scholarship

Background: Prior studies have assessed relationships between gang membership and health-related factors. However, the existing literature has largely failed to consider how individual and broader social contextual factors might be related to such gang involvement among African American females. Thus, the aim of the present study was to identify empirically driven correlates of gang involvement and then better understand the relationship between gang membership and health-related behaviors for African American females, after controlling for covariates of gang involvement. Methods: Data were collected from a convenience sample of detained African American adolescents females, between the ages of 13-17, currently incarcerated in …

Social And Environmental Risk Factors For Anemia And Malnutrition Among Adolescent Girls In Mumbai, India, Dylan E. Graetz

Master's Theses

No abstract provided.

Envisioning The Apocalypse: (Dis)Order, Progress, And Brazil’S Canudos War, 1896-1897, Gray Fielding Kidd

Masters Theses, 2010-2019

This thesis uses the Canudos War (1896-7) as an analytical lens for unpacking issues of class, race, and gender in late nineteenth century Brazil. Brazil’s perhaps bloodiest civil war between millenarian backlanders and the state and federal military sheds light on elite urban social preoccupations during a critical formative period of republican rule. I analyze travelogues, newspaper reports, political cartoons, and other period documents. I do so in order to engage with elite urban Brazilians’ readings of, and prescriptions for, Order and Progress as articulated through questions of gender, class, and race. Throughout this project, I argue that urban sympathetic …

The Effects Of Having Teachers Implement Teacher Child Interaction Training On Language And Communication Development, Chelsea Ann Rainear

Masters Theses, 2010-2019

Prevention and intervention programs for language and communication skills are important, and should be implemented early to gain the maximum benefits. There is evidence that verbal modeling and adult verbal imitation of children may enhance these skills. Teacher training programs have been shown to be effective in modifying students’ behaviors. Speech and language are also forms of behavior, thus the same principles should apply to coaching teachers how to modify verbal behavior to improve their communication skills. McIntosh, Rizza, and Bliss (2000) discussed a need for empirically supported treatments in schools and a need for treatment manuals in order to …

How Do We Conceptualize Depression?: A Mixed Methods Study, Mariafé Taeví Panizo

Masters Theses, 2010-2019

Despite being extensively discussed, the concepts of mental disorder in general and depression in particular remain unclear and no consensual definitions are yet established. Empirical research on how professionals and laypeople think about depression also points to tensions and lack of consensus. However, there still remains much work to be done in order to more effectively and clearly elucidate how depression is conceptualized. Specifically, there has not been an in-depth analysis of the beliefs, values, and justification that guide practitioners in their everyday work regarding mental disorders in general and depression in particular. The purpose of the current mixed methods …

Towards Construct Validity: Investigating The Structure Of The Mental Toughness In Sport Questionnaire (Mtsq-32), Kelly Jane Foelber

Masters Theses, 2010-2019

In effort to gather construct validity evidence for a new measure of mental toughness, the Mental Toughness in Sport Questionnaire (MTSQ-32), confirmatory factor analyses were performed to examine the plausibility of competing theoretical models. This was done in accordance with Benson's (1998) strong program of construct validity. Four primary models were tested: a unidimensional model, a five-factor model based upon social-cognitive personality theory, a five-factor model based upon the commonly identified attributes of mental toughness, and a 10-factor multidimensional model combining the two five-factor models. Further models were tested that expanded upon the four former by including a reverse coding …

Auditory Masking In Spontaneously Hypertensive Rat: An Examination Of The Continuum Of Impulsivity, John Joseph O'Malley

Masters Theses, 2010-2019

Signal detection theory can measure impulsive behavior. To further examine this paradigm, the researcher attempted to replicate previous findings with more experimental control and examine impulsive behaviors in a putative model of Attention Deficit/Hyperactivity Disorder, the Spontaneously Hypertensive Rat. Four strains of rats attempted to discriminate between the presence and absences of a 3 kHz tone within a 5-6 kHz masker; however, only one rat reached stabilization. To aid in training and reduce difficulty of the task, the researcher presented the rat wit forced-choice trials. Although the additional training increased their variability of correct responses, rats were unable to reach …

Investigating The Discrepancies Between Student Perceptions And Faculty Expectations Of Graduate-Level Statistics Preparation, Devon Hopkins Whetstone

Masters Theses, 2010-2019

This study investigated the discrepancies between students’ perceived preparation for graduate-level study in statistics and faculty expected levels of preparation for incoming graduate students. Two 25-item surveys on a 6 point Likert scale were developed and administered to a faculty sample and a student sample for comparison. Overall results showed that students’ perceived level of preparation were equal to faculty expected levels of preparation with respect to statistical knowledge. That is, both groups endorsed the middle of the scale indicating that students generally felt somewhat prepared for graduate-level statistics and faculty generally expected students to feel somewhat prepared for their …

The Effects Of Chronic, Partial Sleep Deprivation On Risk-Taking Behavior In Rats, Ashley Marie Shemery

Masters Theses, 2010-2019

The effects of sleep deprivation on risk-taking behavior have been minimally investigated, observing only the effects of total sleep deprivation in human models. Additionally, the research has shown mixed results. In a chronically sleep deprived society where many people (e.g. military, medical doctors) require rapid decision making to ensure the safety and welfare of others, it is of interest to investigate the effects of chronic partial sleep deprivation on risk-taking behavior in a rodent model. The current study examined the effects of 5 days of partial sleep deprivation on risk-taking behavior in Wistar Han rats as measured by the Rodent …

Back To Nature: The Impact Of Nature Relatedness On Empathy And Narcissism In The Millennial Generation, Anne Loyer Metz

Educational Specialist, 2009-2019

Social science research suggests that the current generation of college students is quite different from previous cohorts of undergraduates. In particular, researchers have discovered that college students, known as “Millennials,” demonstrate lower levels of empathy, higher levels of narcissism, increased use of technology, and decreased time spent outdoors. As counselors working with Millennials, large scale dispositional changes may impact the overall functioning of these individuals. This quantitative study of 140 undergraduates explores the relationship between the constructs of empathy, narcissism, and nature-relatedness among the Millennial generation. Data analysis suggests that there is a statistically significant relationship between nature relatedness and …

Those Who Laugh, Last: Exploring The Use Of Humor As A Vehicle Of Healing Through Personal Reflection, Theory, And Practice, Eleanor Barham Whitehurst

Educational Specialist, 2009-2019

The premise of this paper is to examine the healing and therapeutic nature of humor in the counseling relationship. Discussion will focus on the cognitive, emotional, and physical benefits of humor, as well as the methods and techniques used to implement humor and laughter into therapeutic practice. The best practices, benefits, and recommendations for using humor in the therapeutic relationship are reviewed, emphasizing type of humor and assessing client for appropriate use. Application of humor in times of grief and loss is explored, offering insight to the resilience that can be found in the human spirit. Humor is studied as …

Inhibitory Control And Classroom Behavior In Kindergarten Children, Samantha Anne Tynan

Dissertations, 2014-2019

This study examined the association between direct measures of behavioral inhibition (inhibition of prepotent response, motor inhibition, and delayed gratification) and the classroom behavior of kindergarten children. Participants included 5-6 years old kindergarten students (N=64), 35 boys and 29 girls, at two public elementary schools. Behavioral inhibition was assessed with the Night and Day test, Yes or No test, Draw-A-Line-Slowly task and a measure of Delayed Gratification. Classroom behavior was measured using the Teacher-Child Rating Scale 2.1 (T-CRS 2.1). The results showed no significant gender differences in performance on behavioral inhibition tasks or teacher ratings of classroom behavior. Positive correlations …

Understanding The Gendered Self: Implications From Ei Theory, Ei Self, And The Bevi, Christen Pendleton

Dissertations, 2014-2019

The current study focuses on theory, data and analyses from the Forum BEVI Project (www.ibavi.org/content/featured-projects/), a national learning assessment initiative, with a particular emphasis on the “Gender Traditionalism” scale from the Beliefs, Events and Values Inventory (BEVI). Because Gender Traditionalism is central to Equilintegration Theory (EI Theory), the EI Self and the Beliefs Events and Values Inventory (BEVI), issues of definition, measurement and theory are considered with respect to this model, framework and method along with an examination of data and analyses from the BEVI, which are relevant to a deeper understanding of this construct. Results suggest that the EI …

Using Pedagogical And Rhetorical Strategies To Examine The Medical Ethics Of Human Egg Donation, Emiline Grace Buhler

Masters Theses, 2010-2019

Oocyte retrieval, more commonly referred to as human egg donation, is an outpatient surgical procedure commonly used to obtain reproductive cells for fertility treatments. Before retrieval, donors have to complete physical and mental health screenings, and are responsible for self-injecting a three-week series of intramuscular hormones. The known side effects of human egg donation include: ovarian hyper-stimulation syndrome (OHSS), acute ovarian trauma, infection, and, in extreme cases, infertility. There are currently no empirically-validated studies regarding presence or prevalence of long-term side effects. Further, because of its unique bio-commerce framework, there are currently no federal regulations for this procedure. Increasingly, ethicists, …

Interleukin-3-Deficient Mice Have Increased Resistance To Blood-Stage Malaria, Sarah Rebekah Auclair

Masters Theses, 2010-2019

The contribution of interleukin-3 (IL-3), a hematopoietic growth factor and immunoregulatory cytokine, to resistance to blood-stage malaria was investigated by infecting IL-3-deficient (knockout [KO]) mice with Plasmodium berghei NK65. The results show that endogenous IL-3 significantly alters the susceptibility of BALB/c mice to P. berghei NK65 infection as reflected by measures of survival, anemia, parasitemia, and splenomegaly. Male IL-3 KO mice, but not female mice, were more resistant to infection than wild-type (WT) mice, as evidenced by lower peak parasitemia and prolonged survival. Both male and female IL-3 KO mice had increased splenomegaly and were more anemic than corresponding WT …

The Role Of Ephrin-B3 On Midbrain Topography And Auditory Function, William Andrew Noftz

Masters Theses, 2010-2019

Eph-ephrins are a family of molecular guidance proteins that provide cell-cell interactions necessary for topographic mapping and pattern formation in the developing nervous system. Studies in our laboratory have shown in mouse the transient expression of certain Eph-ephrin members in the developing inferior colliculus (IC) prior to hearing onset. Ephrin-B3 expression, while absent in the central nucleus (CNIC), is highly expressed in extramodular domains of the lateral cortex (LCIC) as well as the mesencephalic midline. We utilize multiple-labeling approaches in control and ephrin-B3 mutants to explore the development of converging CNIC and LCIC afferent patterns. Tract-tracing studies describe the relative …

The Stress Response To An Acute Heavy Resistance Exercise Protocol, Adam J. Sterczala

Master's Theses

Exercise has been shown to induce significant stress and a subsequent inflammatory response characterized by changes in circulating leukocyte populations and inflammatory cytokines and has been well documented following aerobic exercise. Research in regards to the effects of resistance exercise on the stress induced inflammatory response is less prevalent and has shown divergent results, likely due to differences in the exercise protocols used, the time points measured and the subjects involved. Therefore, the purpose of this investigation was to analyze the stress response to an acute heavy resistance exercise protocol (AHREP) in resistance-trained men. Specifically, we examined effects on circulating …

Biocompatible Fluorescent Hydrogel Fiber For Glucose Monitoring, Srilaya Mopidevi

Master's Theses

Diabetes mellitus is one of the leading incurable diseases which may lead to severe health complications due to elevated blood glucose levels. This is mainly caused due to lack of insulin secretion by pancreas (Type I) or when the cells in the body become resistant to insulin (Type II). The key for diabetes treatment is regular monitoring and maintenance of blood glucose levels in the body. We present herein an optical glucose biosensor for glucose monitoring, where a fluorescent enzymatic hydrogel is incorporated with fluorescein, polyethylene glycol and glucose oxidase. Glucose oxidase catalyzes oxidation of glucose to gluconic acid that …

Infants May Be Sensitive To Asynchronous Audiovisual Speech, Kathleen E. Shaw

Master's Theses

No abstract provided.

Anatomically Realistic Structural Modeling Of The Cardiac Purkinje Network: A Basis For Studying Contributions Of The Conduction System To Ventricular Arrhythmias, Benjamin Liu

Theses

A cardiac arrhythmia is a potentially-lethal event in which the normally orderly electrical activity in the heart is disrupted -- it becomes disorganized and compromises effective contraction. To better understand arrhythmia dynamics to develop potential therapies and treatments, experimental, computational, and mathematical tools are required. Simulations of cardiac tissue provide valuable insight into the dynamics of life-threatening cardiac arrhythmias, and though much work has been done in this area, the role of the Purkinje network during ventricular arrhythmias has largely been ignored. The function of the Purkinje network is crucial to normal heart rhythm, so its inclusion into cardiac structural …

State V. Vaughn Respondent's Brief Dckt. 41599

Not Reported

No abstract provided.

Rights In The Balance: Rights Consciousness, Rights Claiming And Work/Life Balance Policies In The U.S., Sarah Hampson

Doctoral Dissertations

This dissertation traces the process by which individual women come to form their consciousness of work/life balance law and policies that are available to them. Engaging primarily with Law and Society literature on legal consciousness formation, I employ a “process-based” approach, in order to conceptually disentangle the various threads that comprise the sources of legal consciousness formation. I analyze three dimensions that matter to the construction of legal consciousness: the institutional, the ideological, and the instrumental. In doing so, I seek to detect the connection between the individual and the social in the formation of legal consciousness. I use interpretive …