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Surveilans Aedes Aegypti Di Daerah Endemis Demam Berdarah Dengue, Sunaryo Sunaryo, Nova Pramestuti

Kesmas

Demam Berdarah Dengue (DBD) perlu mendapat perhatian serius karena masih menjadi masalah kesehatan di Indonesia dan di beberapa daerah masih sering terjadi kejadian luar biasa. Di Jawa Tengah, kasus DBD cenderung meningkat setiap tahunnya terutama pada tahun 2012. Penelitian ini bertujuan menganalisis parameter entomologi dan menggambarkan jenis tempat penampungan air. Penelitian dilakukan di Kabupaten Grobogan, Purbalingga, Kendal dan Kota Semarang pada bulan Juni _ Oktober 2013 dengan desain potong lintang. Survei jentik dilakukan untuk melihat keberadaan tempat penampungan air pada 100 rumah. Masing-masing kabupaten dipilih tiga lokasi desa endemis DBD. Hasil survei digunakan untuk menghitung nilai parameter entomologi. Hasil penelitian …

A Risk Modeling Framework For The Pharmaceutical Industry, Warren Adis

Communications of the IIMA

This conceptual paper seeks to advance a theoretical discussion on risk modeling and how it is used within the context of business process modeling. It discusses developments in risk modeling and then shows how they have been applied to the USA pharmaceutical industry. The pharmaceutical industry is a particularly interesting example in that it is bound on one side by stringent USA government mandates, and on the other by a risk adverse consumer population. A third aspect, the expanding cost structure of drug production and compliance, adds to the complexity of the problem. The discussion of risk in this paper …

Maple Syrup Value Systems And Value Chains - Considering Aboriginal And Non-Aboriginal Perspectives, Brenda Murphy, Annette Chrétien, Grant Morin

Contemporary Studies

Harvested from both intensive sugar maple stands and diverse mixed forest ecosystems across Ontario, maple syrup is an important rural and Aboriginal non-timber forest product that contributes to social, economic and environmental sustainability. This paper presents our ongoing work to map Ontario’s maple syrup value system from two different perspectives, Aboriginal and non-Aboriginal. In the economic sense, analyses of value systems are useful for members to identify the opportunities and challenges they are facing to advance industry growth and innovation. In the social and environmental sense, these analyses provide a window into how different worldviews and belief systems can lead …

The Effect Of Tuning Cold Plasma Composition On Glioblastoma Cell Viability, Xiaoqian Cheng, Jonathan H. Sherman, William Murphy, Edward Ratovitski, Jerome Canady, Michael Keidar

Biochemistry and Molecular Medicine Faculty Publications

Previous research in cold atmospheric plasma (CAP) and cancer cell interaction has repeatedly proven that the cold plasma induced cell death. It is postulated that the reactive oxygen species (ROS) and reactive nitrogen species (RNS) play a major role in the CAP cancer therapy. In this paper, we seek to determine a mechanism of CAP therapy on glioblastoma cells (U87) through an understanding of the composition of the plasma, including treatment time, voltage, flow-rate and plasma-gas composition. In order to determine the threshold of plasma treatment on U87, normal human astrocytes (E6/E7) were used as the comparison cell line. Our …

Developing An Ontario Maple Syrup Sector Profile: A Value Chain Analysis, Grant Morin

Geography and Environmental Studies Major Research Papers

Through a sectorial profile, this study identifies the maple syrup value chain’s key players, processes, activities and inter-intra industry relationships (social capital) providing baseline data on the current status of the industry and an overall picture of the maple syrup value chain for members and new entrants. The study found that a) technological advancements over the years have lead to great efficiencies and eased the labour requirement; b) that strong social connections have great impact on marketing and retail of syrup; c) that innovation is found not only through research and development sectors of large companies but also from a …

Exposure To Fine Particulate Matter During Pregnancy And Risk Of Preterm Birth Among Women In New Jersey, Ohio, And Pennsylvania, 2000–2005, Kristen M. Rappazzo, Julie L. Daniels, Lynne C. Messer, Charles Poole, Danelle T. Lobdell

Community Health Faculty Publications and Presentations

Background: Particulate matter < 2.5 micrometers in aerodynamic diameter (PM2.5) has been variably associated with preterm birth (PTB).

Objective: We classified preterm births into four categories (20–27, 28–31, 32–34, and 35–36 weeks completed gestation) and estimated risk differences (RD) for each category in association with a 1-µg/m3 increase in PM2.5 exposure during each week of gestation.

Methods: We assembled a cohort of singleton pregnancies that completed at least 20 weeks of gestation during 2000-2005 using live birth certificate data from three states (Pennsylvania, Ohio, and New Jersey) (n = 1,940,213; 8% PTB). We estimated mean PM2.5 exposures for each week of gestation from monitor-corrected Community Multi-Scale Air Quality modeling data. RDs were …

The National Medical Association’S Call For Responsibility During The Progressive Era: The Duty Of Black Physicians To Improve Conditions In Black Communities To Combat Tuberculosis Mortality Rates., Elizabeth R. Daniels

Constructing the Past

The National Medical Association (NMA) was founded in 1895 after the American Medical Association denied a group of black physicians membership. Black physicians used this organization as a platform to launch a three-tiered approach to combating the tuberculosis epidemic: debunking popular beliefs of black biological inferiority, proactive education of the black community on proper hygiene and behavior, and lobbying to gain support from social reforms and campaigns by targeting white anxieties and morals.

The NMA identified the causes of high death rates among black populations from tuberculosis as environmental, economic and social conditions. They placed the primary responsibility of changing …

Interaction Effects Between The 5-Httlpr Genotype And Family Environments On Adolescent Alcohol Use And Misuse, Jueun Kim

Theses - ALL

Emerging evidence shows that the 5-HTTLPR genotype interacts with social environments and influences drinking behaviors. However, few studies have examined interaction effects between the 5-HTTLPR genotype and specific aspects of family environments on adolescent drinking. The present study investigated whether the effects of family conflict or parental monitoring on adolescent drinking differed as a function of the 5-HTTLPR genotype cross-sectionally and longitudinally. It was replicated in two independent samples consisting of 175 adolescents in the U.S. and 4,916 adolescents in the U.K. The results of path analyses and multi-group analyses showed that, in the two samples, the 5-HTTLPR low-activity allele …

Investigating The Role Of Social Environmental Stress And Implicit Motives In Predicting Salivary Alpha-Amylase Reactivity To The Social Competence Interview, Jun A. He

Theses - ALL

Salivary alpha-amylase is emerging as a promising proxy for assessing sympathetic-adrenal-medullary (SAM) axis activity. However, it is not known whether a brief semi-structured behavioral assessment, such as the social competence interview (SCI), also elicits alpha-amylase changes. I hypothesized that (1) the SCI would elicit alpha amylase reactivity, (2) social environmental stress (i.e, high levels of exposure to violence during childhood and low perceived community social status) would predict the alpha-amylase response to the interview and (3) that agonistic striving would mediate the relationship between social environmental stress and amylase reactivity. The study sample was comprised of healthy young adults aged …

Landscape Factors That Affect Acid-Base Chemistry Of Adirondack Long-Term Monitoring (Altm) Lakes, Zheng Dong

Theses - ALL

The Adirondack region has been affected by acid deposition for multiple decades. Atmospheric deposition of sulfur and nitrogen has decreased since the 1970s because of the 1970 and 1990 Clean Air Act Amendments (CAAA) as well as the NOX Budget Program. Previous studies have related the long-term changes in Adirondack lake water chemistry to decreases in atmospheric deposition and emission controls. However, relatively limited research has been conducted on the spatial patterns and the role of different landscape factors on the recovery of lake water chemistry in the Adirondacks. The objective of this study was to investigate the relations of …

Structure, Paleolimnology And Basin History Of The East Kivu Graben, Lake Kivu, Rwanda From Offshore Seismic Reflection Data, Douglas Alan Wood

Theses - ALL

Lake Kivu, located at the topographic high point of the western branch of Africa's Great Rift Valley, is regularly subjected to large-magnitude seismic events, violent volcanic discharges, and possible limnic eruptions which pose substantial geohazards to the ~two million Congolese and Rwandan people living around its basin. Although most of the western branch of Africa's Great Rift Valley is amagmatic, Lake Kivu is bordered to the north and south by two volcanic provinces. Subaqueous springs, charged by the active Virunga Magmatic Complex at the north end of the lake, currently inject gas into the deep- hypolimnion, where it remains in …

Cripping The Memoir: Unraveling The Discourse Around Disabled Athletes' Identities, Jessica Kerley

Theses - ALL

This thesis rhetorically examines the discourse surrounding disability and body capabilities. I employ feminist theory, queer theory, disability, theory and performance theory as I analyze the memoirs and media surrounding two disabled elite athletes, Sarah Reinertsen and Mark Zupan. I examine the construction of identity for these athletes and what the language use surrounding these athletes means to the current status of disability discourse. These memoirs have the potential to reach a large lay audience, and therefore, the opportunity to educate and challenge assumptions. My analysis leads me to conclude that the limitations of memoir and societal pressures allow for …

Hurricane Activity And The Large-Scale Pattern Of Spread Of An Invasive Plant Species, Ganesh P. Bhattarai, James T. Cronin

Faculty Publications

Disturbances are a primary facilitator of the growth and spread of invasive species. However, the effects of large-scale disturbances, such as hurricanes and tropical storms, on the broad geographic patterns of invasive species growth and spread have not been investigated. We used historical aerial imagery to determine the growth rate of invasive Phragmites australis patches in wetlands along the Atlantic and Gulf Coasts of the United States. These were relatively undisturbed wetlands where P. australis had room for unrestricted growth. Over the past several decades, invasive P. australis stands expanded in size by 6-35% per year. Based on tropical storm …

Garden Of Eden: Software Packages For The Generation And Rendering Of Visually Realistic Trees And Forests, William B. Jackson

Computer Science Technical Reports

Garden of Eden is an exercise in procedural generation of lifelike worlds. It randomly generates a forest scene of realistically shaped and proportioned asymmetric trees on top of a simple topographical map. This map is then rendered in an HTML5 3D canvas, with support for user navigation. The end result of this project is a sort of game, though without any goal, narrative, or creative purpose. It is simply a static rendering of a natural environment, open for exploration, closed to manipulation, exploring how users find visual pleasure and meaning in virtual environments. The passive interaction of the user is …

May 30, 2014 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Electrochemical Control Of Bacterial Persister Cells, Tagbo Herman Roland Niepa

Dissertations - ALL

The emergence of antibiotic-resistant bacteria has presented an increasing challenge to infection control. Conventional methods of antibacterial treatment involving high dose of antibiotics or surgical intervention have proven insufficient for eradicating persistent infections, such as those associated with medical implants. It is well recognized that bacterial populations commonly contain a small percentage of phenotypic variants, known as persister cells, which are metabolically inactive and extremely tolerant to antibiotics. When the antibiotic treatment is stopped, surviving persister cells can regenerate the bacterial population with a similar percentage of persister cells. Thus, persistence presents a great challenge to curing chronic infections.

In …

Laboring Lesbians At Gas Stations: Pumping The "Good Life", Amy Jo Tweedy

Dissertations - ALL

This dissertation project is an interdisciplinary exploration of laboring lesbian bodies within the context of U.S. gas stations. I begin with an investigation of the history of gas stations in connection with the oil industry and the company for which they work. In addition, I examine how institutions of class, gender and sexuality are imprinted onto laboring lesbian bodies within the workplace. I suggest that the work within U.S. gas stations is now primarily feminized labor as is typical of the service economy. I also highlight the ways in which sexuality matters in the workplace through an analysis of the …

The Effects Of Cold Adaptation On The Growth And Development Of The Neandertal Cranial Base, Sarah Caldwell

Theses and Dissertations

Neandertals and modern humans possess very different craniofacial shapes. Some recent work has attributed these contrasting shapes specifically to differences in brain development, which are extrapolated to mean differences in cognitive function. However, this may not necessarily be the case. In this paper, it is suggested that a size increase in the cranial base and rapid cranial growth are due not to cognitive differences, but environmental factors, specifically Neandertal adaptation to cold. Adaptation to cold would not only explain the more rapid growth of the Neandertal cranium, but also elongation of the cranial base via elongation of the nasopharynx for …

The Relationships Between Stress, Social Support, Maternal Self-Efficacy, Maternal Depression, Maternal Reports Of Child Demandingness And Maternal Reports Of Child Social And Emotional Quality Of Life In A Sample Of Overweight And Obese Women Two Years Post Childbirth, Elizabeth Banks Feldhousen

Dissertations - ALL

Emotional problems in the postpartum period affect both mothers and children. This is particularly salient for mothers who are overweight or obese, who have been shown to be more at risk for adverse postpartum outcomes than mothers who were of a normal weight before pregnancy. The current study examined the relationships between maternal stress, maternal depression, social support, maternal self-efficacy, maternal perceptions of child demandingness, and child social and emotional quality of life (as the outcome variable) in the two years after a second childbirth among a sample of overweight and obese women. The subjects of this analysis were the …

Protist Facilitated Transport In An Artificial Soil Micromodel, Rebecca L. Rubinstein

Master's Theses

The soil microhabitat contains a complex network of microbial, biochemical, and physical interactions, all of which have very important implications for remediation technologies as well as agriculture. As a result, observing and quantifying this environment has been of recurring interest to scientists and engineers, but by nature many of these processes are difficult if not impossible to observe in situ. To that end, we have developed techniques utilizing soil-structured microfluidic devices for direct observation of soil microbial processes. Specifically, natural soil protists were observed moving through fabricated artificial soil networks, and their impact on the spatial and temporal distribution …

Potential Impacts To Resident Populations, Susitna-Watana Hydroelectric Project, Megan Ross

Geography and the Environment: Graduate Student Capstones

In 2014, the Alaska Energy Authority is preparing to construct a hydropower dam on Alaska's Susitna River, known as the Susitna-Watana Hydroelectric Project. Changes to water levels, sediment content, and flow rates are likely to affect the river itself and the salmon that are sustained by the Susitna ecosystem. The potential geomorphological and biological impacts of the dam as they could affect activity in the local communities are studied using currently available data. GIS tools are applied to identify areas of reservoir fill, risk of erosion, and endangerment of salmon habitat; then compare these impact areas to areas used by …

Pd2/Paf1 Depletion In Pancreatic Acinar Cells Promotes Acinar-To-Ductal Metaplasia., Parama Dey, Satyanarayana Rachagani, Arokia P. Vaz, Moorthy P. Ponnusamy, Surinder K. Batra

Journal Articles: Biochemistry & Molecular Biology

Pancreatic differentiation 2 (PD2), a PAF (RNA Polymerase II Associated Factor) complex subunit, is overexpressed in pancreatic cancer cells and has demonstrated potential oncogenic property. Here, we report that PD2/Paf1 expression was restricted to acinar cells in the normal murine pancreas, but its expression increased in the ductal cells of KrasG12D/Pdx1Cre (KC) mouse model of pancreatic cancer with increasing age, showing highest expression in neoplastic ductal cells of 50 weeks old mice. PD2/Paf1 was specifically expressed in amylase and CK19 double positive metaplastic ducts, representing intermediate structures during pancreatic acinar-to-ductal metaplasia (ADM). Similar PD2/Paf1 expression was observed in murine pancreas …

Starved For Information: The Conflict Between Mobilizing Hunger Strikes And Distracting Media Frames, Alicia Wright

Theses - ALL

This study considers the newspaper coverage of Irom Sharmila's on-going, 13-year hunger strike in India to question how information from the media plays a role in generation of social movement conflict. With specific attention paid to the cultural context and method of protest, the study applies theories of conflict, social movement planning, and framing to examine whether the hunger strike elicits coverage that includes salient frames generated by the movement. Such coverage could signify a potential shift in the protest paradigm applied to English-language newspapers in India. Through a quantitative content analysis, articles pertaining to Irom Sharmila's hunger strike against …

20 Weeks, 13 Hours, 140 Characters: The Abortion Controversy In The Texas State Senate And Online, Elyse Nicole Janish

Theses - ALL

The abortion controversy in America has long been characterized by problematic discourse in which neither prolife nor prochoice groups make headway in persuading the other side. This thesis examines the discourse of the abortion controversy as it played out in and around the Texas State Senate on June 25th, 2013, during a filibuster of a restrictive abortion bill known as Senate Bill 5 (SB5), by Senator Wendy Davis (D-Fort Worth). The analysis focuses on three sets of data: first, the testimonies authored by citizen protestors and animated by Senator Davis; second, the question-and-answer period between Senator Davis and Republican Senator …

An Epidemiology Of Big Data, John Mark Young

Dissertations - ALL

Federal legislation designed to transform the U.S. healthcare system and the emergence of mobile technology are among the common drivers that have contributed to a data explosion, with industry analysts and stakeholders proclaiming this decade the big data decade in healthcare (Horowitz, 2012). But a precise definition of big data is hazy (Dumbill, 2013). Instead, the healthcare industry mainly relies on metaphors, buzzwords, and slogans that fail to provide information about big data's content, value, or purposes for existence (Burns, 2011). Bollier and Firestone (2010) even suggests "big data does not really exist in healthcare" (p. 29). While federal policymakers …

Seasonal And Sex Differences In The Effects Of Melatonin On Brain Arginine Vasotocin In Green Treefrogs (Hyla Cinerea): Relationship To Melatonin Receptor 1a, Christina Marie Howard

Dissertations and Theses

Critical life history events such as breeding, migration and hibernation must take place in the correct environmental context to minimize deleterious consequences on survival and reproductive fitness. Neuroendocrine mechanisms synchronizing internal physiological states with extrinsic environmental cues are vital to timing life history events appropriately. Secretion of the pineal hormone melatonin is sensitive to light and temperature cues, which provides a physiological indicator of time of day and time of year for organisms. Melatonin influences seasonal reproduction in a variety of vertebrates, likely by altering the synthesis and/or release of reproductive neuropeptides in the brain. The neuropeptides arginine vasotocin and …

The Effect Of Maternal Separation And Postnatal Oxytocin Administration On Social Recognition In Adolescent Female Mice, Nathaniel Richard Thomas

Dissertations - ALL

A vast body of literature indicates that exposing rodents to maternal separation during infancy results in long - term developmental changes in physiological, behavioral, and psychological domains. Because several previous studies have indicated that maternal separation may be detrimental to the processing and discrimination of social cues, the primary aim of this dissertation was to determine whether separating female infant mouse pups from their mother, but not siblings, for 3 hrs daily, during the first two weeks of life, influences social recognition during adolescence (Experiment 1). This dissertation also sought to evaluate whether postnatal administration of the oxytocin would influence …

Father Involvement In Low-Income Families: Evidence On Predictors Of Involvement From Two Large Scale Maternal-Child Health Datasets, Mark Dean Thomas

Dissertations - ALL

The literature on father involvement in low-income, racially diverse families has grown in recent years, but is far from complete. Continued research is needed to better understand those factors that support father involvement, which has been identified to be a key contributor to maternal and child wellbeing. This dissertation examines the utility of using existing, large-scale maternal-child health datasets to generate insights into the processes that contribute to father involvement. Two large scale maternal-child health data sets on low-income families were examined to improve our understanding of the nature of father involvement at birth and in infancy/early childhood. Multinomial logistic …

Azd8931, An Equipotent, Reversible Inhibitor Of Signaling By Epidermal Growth Factor Receptor (Egfr), Her2, And Her3: Preclinical Activity In Her2 Non-Amplified Inflammatory Breast Cancer Models., Zhaomei Mu, Teresa Klinowska, Xiaoshen Dong, Emily Foster, Chris Womack, Sandra V Fernandez, Massimo Cristofanilli

Department of Medical Oncology Faculty Papers

INTRODUCTION: Epidermal growth factor receptor (EGFR) overexpression has been associated with prognostic and predictive value in inflammatory breast cancer (IBC). Epidermal growth factor receptor 2 (HER2) overexpression is observed at a higher rate in IBC compared with noninflammatory breast cancer. Current clinically available anti-HER2 therapies are effective only in patients with HER2 amplified breast cancer, including IBC. AZD8931 is a novel small-molecule equipotent inhibitor of EGFR, HER2, and HER3 signaling. In this study, we investigated the antitumor activity of AZD8931 alone or in combination with paclitaxel using preclinical models of EGFR-overexpressed and HER2 non-amplified IBC cells.

METHODS: Two IBC cell …

Patterned Biofilm Formation To Investigate Bacteria-Surface Interactions, Huan Gu

Dissertations - ALL

Bacterial adhesion to surfaces and subsequent formation of microcolonies play important roles in biofilm formation, which is a major cause of chronic infections and persistent biofouling. Despite the significance, mechanistic understanding of biofilm formation is still hindered by the structural heterogeneity in biofilms; and effective control of biofilm formation remains challenging. Biofilm formation is a dynamic process that involves numerous changes in bacterial gene and protein expression. These changes are highly sensitive to environmental factors such as surface chemistry, topography, charge, and hydrophobicity. To better control biofilm morphology and specifically investigate the effects of these factors, a platform was developed …