Digital Commons Network^™

Controls On Macrotidal Rip Current Circulation And Hazard, Tim Scott, Gerd Masselink, Martin J. Austin, Paul Russell

School of Biological and Marine Sciences

No abstract provided.

Response Of Wave-Dominated And Mixed-Energy Barriers To Storms, Gerd Masselink, Heteren S Van

School of Biological and Marine Sciences

No abstract provided.

Identification Of Genes Required For Soil Survival In Burkholderia Thailandensis By Transposon-Directed Insertion Site Sequencing, Ah Bishop, Pa Rachwal

School of Biological and Marine Sciences

Transposon-directed insertion site sequencing was used to identify genes required by Burkholderia thailandensis to survive in plant/soil microcosms. A total of 1,153 genetic loci fulfilled the criteria as being likely to encode survival characteristics. Of these, 203 (17.6 %) were associated with uptake and transport systems; 463 loci (40.1 %) coded for enzymatic properties, 99 of these (21.4 %) had reduction/oxidation functions; 117 (10.1 %) were gene regulation or sensory loci; 61 (5.3 %) encoded structural proteins found in the cell envelope or with enzymatic activities related to it, distinct from these, 46 (4.0 %) were involved in chemotaxis and …

Catastrophe Models For Cognitive Workload And Fatigue In A Vigilance Dual Task, Stephen J. Guastello, Matthew Malon, Paul Timm, Kelsey Ann Weinberger, Hillary Gorin, Megan Fabisch, Kirsten Poston

Psychology Faculty Research and Publications

Objective: This study investigated two cusp catastrophe models for cognitive workload and fatigue for a vigilance dual task, the role of emotional intelligence and frustration in the performance dynamics, and the dynamics for individuals and teams of two participants.

Background: The effects of workload, fatigue, practice, and time on a specific task can be separated with the two models and an appropriate experimental design. Group dynamics add further complications to the understanding of workload and fatigue effects for teams.

Method: In this experiment, 141 undergraduates responded to target stimuli that appeared on a simulated security camera display at three rates …

Comparing Students' Perceptions Of Online Language Learning To Traditional Learning, Noreen La Piana

Doctoral Dissertations and Projects

This study examined students' perceptions towards online language learning and face-to-face learning. A survey of multiple intelligences (McClelland & Conti, 2008) combined with an Online Learning Readiness Survey (OLRS) survey (Dray, Lowenthal, Miszkiewicz, Ruiz-Primo, & Marczynski, 2011) was distributed to 2,177 community college and university students in order to measure the strength of each of the nine intelligences each student possessed, as well as their perceptions of readiness for online language learning. Student preference for online/hybrid versus traditional language class was also considered. The three research questions involved an investigation of: 1) the differences between students who attended an online/hybrid …

The Social Model's Case For Inclusion: "Motivating Factor" And "But For" Standards Of Proof Under The Americans With Disabilities Act And The Impact Of The Social Model Of Disability On Employees With Disabilities, Lisa Schlesinger

Cardozo Law Review

No abstract provided.

Electro-Deformation Of A Moving Boundary: A Drop Interface And A Lipid Bilayer Membrane, Herve Nganguia

Dissertations

This dissertation focuses on the deformation of a viscous drop and a vesicle immersed in a (leaky) dielectric fluid under an electric field. A number of mathematical tools, both analytical and numerical, are developed for these investigations. The dissertation is divided into three parts. First, a large-deformation model is developed to capture the equilibrium deformation of a viscous spheroidal drop covered with non-diffusing insoluble surfactant under a uniform direct current (DC) electric field. The large- deformation model predicts the dependence of equilibrium spheroidal drop shape on the permittivity ratio, conductivity ratio, surfactant coverage, and the elasticity number. Results from the …

Kinetic Analysis Of Thiol Oxidation To Study The Effects Of Fluorinated Groups On Metal Phthalocyanine Catalysts, Nellone Eze Reid

Dissertations

The oxidation of thiol (RSH) to disulfide (RSSR) is important biologically and industrially. Corrosive and malodorous thiols exist as contaminants in wastewater discharge from mining facilities, pulp and paper mills, tanneries, and oil refineries. The elimination of thiols from petroleum products is necessary for even cleaner fuels. Thiols in gas products can also inhibit catalyst activity for some downstream processes.

Experiments and mechanistic kinetic studies were conducted for the aerobic oxidation of 2-mercaptoethanol (2-ME) and 4-fluorobenzenethiol (4-FBT) catalyzed by cobalt phthalocyanines: H₁₆PcCo, F₁₆PcCo, and F₆₄PcCo, each exhibiting a metal center subject to increasing Lewis …

Computational Methods For The Analysis Of Next Generation Sequencing Data, Wei Wang

Dissertations

Recently, next generation sequencing (NGS) technology has emerged as a powerful approach and dramatically transformed biomedical research in an unprecedented scale. NGS is expected to replace the traditional hybridization-based microarray technology because of its affordable cost and high digital resolution. Although NGS has significantly extended the ability to study the human genome and to better understand the biology of genomes, the new technology has required profound changes to the data analysis. There is a substantial need for computational methods that allow a convenient analysis of these overwhelmingly high-throughput data sets and address an increasing number of compelling biological questions which …

Characterizing Motor Control Signals In The Spinal Cord, Yi Guo

Dissertations

The main goal of this project is to develop a rodent model to study the central command signals generated in the brain and spinal cord for the control of motor function in the forearms. The nature of the central command signal has been debated for many decades with only limited progress. This thesis presents a project that investigated this problem using novel techniques. Rats are instrumented to record the control signals in their spinal cord while they are performing lever press task they are trained in. A haptic interface and wireless neural data amplifier system simultaneously collects dynamic and neural …

Nanocarbon Immobilized Membrane For Separation And Analysis, Madhuleena Bhadra

Dissertations

Membrane processes classically cover a wide range of applications associated with various aspects of separation and purification. Over the last few years, membrane based processes have received much interest due to their compact and modular architecture, low energy consumption and cost effective separation. With the development of diverse nanomaterials which can serve as nanosorbents, or provide specific morphology for selective solute transport, recent years have witnessed the emergence of nanocarbon based membranes that can address some of the limitations of conventional membrane processes and make feasible the next generation of breakthroughs.

The objective of this research is the exploration of …

Salmon Hatcheries As Fish Factories: Forgetting The Lessons Of Leopold, Michael C. Blumm

Seattle Journal of Environmental Law

No abstract provided.

The Legal And Enviromental Implications Of The Washington Shellfish Initiative: Is It Sustainable?, Lindsey Ward

Seattle Journal of Environmental Law

No abstract provided.

2014 Rose-Hulman Institute Of Technology: One Hundred And Thirty-Sixth Commencement, Rose Hulman

Commencement Programs

No abstract provided.

The Murray Ledger And Times, May 31-June 1, 2014, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Optimizing Alginate-Chitosan Microcapsules Using Co-Axial Air Flow Method As 3d Stem Cell Microenvironment, Noel Alfonso

Theses

Microencapsulation of cells is gaining popular interest in the field of biomedical engineering because it provides a more effective 3D scaffold that can mimic the cell microenvironment. The benefits of using microcapsules are biocompatibility, biodegradability, nontoxicity, and formation under mild gelation conditions. In this study, the ability of the alginate microcapsules to control the proliferation and differentiation of mouse OCT4-GFP embryonic stem cells is investigated. Microcapsules are produced by extrusion of alginate into a calcium chloride gelation bath with the aid of a co-axial air flow. It is shown that the size of the spheres is controlled based on needle …

Hydrodynamic Cfd Modeling Of A Pharmaceutical Reactor Vessel Provided With A Retreat-Blade Impeller Under Different Baffling Conditions, Christopher G. Foehner

Theses

In the pharmaceutical industry, glass-lined reactors and vessels are often utilized to carry out a variety of different unit operations. Within these systems, both the vessel and impellers are typically glass-lined in order to provide superior corrosion resistance, prevent product contamination, and enhance cleanability. This approach, in turn, often requires the use of different, and sometimes sub-optimal, baffling conditions, which affect the hydrodynamics of the vessels and the reactor performance.

Computational Fluid Dynamics (CFD) is a computational tool that employs numerical methods and algorithms to discretize and numerically solve partial differential equations (PDEs) representing mass, energy, and momentum conservation equations …

Risk Prediction With Genomic Data, Bharati Jadhav

Theses

Genome wide association study (GWAS) is widely used with various machine learning algorithms to predict disease risk. This thesis investigates this widely used approach of GWAS using Single Nucleotide Polymorphism (SNP) genotype data and a novel approach of disease risk prediction with whole exome sequencing data, namely Whole Exome Wide Association Study (WEWAS). It further applies a discriminating machine learning algorithm, namely a Support Vector Machine (SVM) with different Kernel functions. For this study, only SNPs generated using genotyping technology, which focuses more on common variants, are used initially for disease prediction. Later, the whole exome data generated using Next …

Combustion Of Fine Magnesium Particles, Song Wang

Theses

Recent interest in developing Al-Mg alloys as reactive materials prompted studies of combustion mechanisms for particles of such alloys with different Al/Mg ratios. Reference experiments with pure Al and Mg powders are also desired to better understand and model combustion of the respective alloys. While combustion of pure Al powders has been addressed in many recent studies, combustion of magnesium explored mostly coarse, 50 μm, and larger particles. This effort is focused to characterize and understand combustion dynamics for fine Mg powders. Spherical, micron-sized magnesium particles were introduced in an air-acetylene flame using a custom-made screw feeder. Particles were observed …

Assessment Of A Marine Polysaccharide For Use As Excipient In Pharmaceutical Hot-Melt Extrusion, Qing Ye

Theses

Pharmaceutical Hot Melt Extrusion (HME) is currently investigated by both industry and academia as a method for manufacturing solid oral dosages with improved bioavailability of poorly-water soluble active pharmaceutical ingredients (APIs) and control drug release of water-soluble APIs. Although HME is traditionally utilizing synthetic polymers to produce such dosages, biopolymers constantly gain ground by virtue of renewability, biocompatibility and in some cases biodegradability. In this work, the possibility of using Keltone, a marine polysaccharide derived from brown seaweed, as a polymeric excipient for pharmaceutical HME is explored. Keltone is insoluble in acidic pH and soluble in basic pH, therefore making …

Dispersion And Dissolution Kinetics Of Api Particles In Pharmaceutical Hot Melt Extrusion, Wang Zhan

Theses

Pharmaceutical Hot Melt Extrusion (HME) is essentially a special case of polymer compounding. The elementary steps involved in traditional plastics melt processing are handling of particulates, melting, dispersive and distributive mixing, devolatilization and stripping, and finally pressurization and pumping. However, for pharmaceutical HME, the dissolution of the API (Active Pharmaceutical Ingredient) is an additional and very important elementary step, along with the melting of the polymeric excipient that precedes it, and mixing which accelerates the dissolution process. A major concern in pharmaceutical HME is the thermal degradation of the API. To avoid overexposure of API to heat while ensuring complete …

Evaluation Of Methods To Account For Release From Nanofiber Scaffolds, Jennifer Moy

Theses

Electrospinning is a common technique utilized to form fibers from the micro- to nanometer range. Nanofibers form through electrospinning can be utilized as scaffolds since the fiber structures are similar to the structures within the extracellular matrix. Researchers use additives, such as growth factors, to help facilitate cell proliferation and function. Also, researchers are attempting to use electrospun fibers for drug delivery and as wound dressings since the electrospun fibers have high surface area to volume ratio. In both situations, the release of either the additive or the drug needs to be controlled so that the fibers would release the …

Experimental Determination Of The Mixing Requirements For Solid Suspension In Pharmaceutical Stirred Tank Reactors, Anqi Zhou

Theses

Glass and glass-lined, stirred-tank reactors are of significant importance in the pharmaceutical and related industries. Because of fabrication issues, a retreat blade impeller (RBI) with a low impeller clearance off the tank bottom is commonly used in glass-lined reactors, typically combined with a single baffle (providing only partial baffling conditions) mounted from the top of the reactor. In addition, these reactors are often provided with a torispherical bottom. Other configurations are also used, including full baffling or no baffles at all, hemispherical bottoms, and different impeller types. Despite their common use, some of the most important mixing characteristics of this …

Approach To Flood Mitigation - A Post Sandy Study In New Jersey Meadowlands Area, Banshari Datta

Theses

In the last decade the continuous change in the climate has resulted in an increased frequency of natural catastrophic events and the magnitude of their impact. The immense damage caused by such events brought to light the vulnerabilities of the impacted communities. Coastal communities are alarmingly vulnerable due to flood and storm surge impacts such as those caused by super storm Sandy in 2012. In order to mitigate this risk, the communities need to look beyond the short term recovery measures, and build a sustainable community by implementing long term mitigation measures. The objective of this thesis is to investigate …

Can Retributivism Be Saved?, Chad Flanders

BYU Law Review

Retributive theory has long held pride of place among theories of criminal punishment in both philosophy and in law. It has seemed, at various times, either much more intuitive, or rationally persuasive, or simply more normatively right than other theories. But retributive theory is limited, both in theory and practice, and in many of its versions is best conceived not as a theory of punishment in its own right, but instead as shorthand for a set of constraints on the exercise of punishment. Whether some version of retributive theory is a live possibility in the contemporary world remains very much …

Disincentivizing Elder Abuse Through Disinheritance: Revamping California Probate Code § 259 And Using It As A Model, Travis Hunt

BYU Law Review

No abstract provided.

Law And Resilience: Mapping The Literature, Tracy-Lynn Humby

Seattle Journal of Environmental Law

No abstract provided.

The Not-So-Endless Ocean: How The Cost Of Convenience Is Closing In On Us, Rachel Emens

Seattle Journal of Environmental Law

No abstract provided.

Down Syndrome: An Investigation Into Effective Assessment And Intervention To Increase Overall Communication Abilities, Tricia M. Schutz

Research Papers

No abstract provided.

Evolutionary Operating Systems, Ml Phillips

School of Art, Design and Architecture

No abstract provided.