Digital Commons Network^™

Cloudy With A Chance Of Copepods, Tracey Bentley

UNH Today Archive

No abstract provided.

Natural Variation In Fish Transcriptomes: Comparative Analysis Of The Fathead Minnow (Pimephales Promelas) And Zebrafish (Danio Rerio)., Rong-Lin Wang, David C. Bencic, Natália Garcia-Reyero, Edward J. Perkins, Daniel L. Villeneuve, Gerald T. Ankley, Adam D. Biales

IGBB Publications

Fathead minnow and zebrafish are among the most intensively studied fish species in environmental toxicogenomics. To aid the assessment and interpretation of subtle transcriptomic effects from treatment conditions of interest, better characterization and understanding are needed for natural variation in gene expression among fish individuals from lab cultures. Leveraging the transcriptomics data from a number of our toxicogenomics studies conducted over the years, we conducted a meta-analysis of nearly 600 microarrays generated from the ovary tissue of untreated, reproductively mature fathead minnow and zebrafish samples. As expected, there was considerable batch-to-batch transcriptomic variation; this "batch-effect" appeared to differentially impact subsets …

Dancing Through Life: Allosteric Transitions And Structural Analysis Of Hsp70 And Hsp110 Chaperone Proteins, Gabrielle Stetz, Gennady M. Verkhivker

Student Scholar Symposium Abstracts and Posters

The molecular chaperone protein Hsp70 is centrally involved in cellular homeostasis by assisting in the folding and degradation of protein substrates. Hsp70 is joined by co-chaperones, such as Hsp110, which contribute to specialized tasks of the Hsp70 complex. Imbalances of this heat shock protein system are believed to be involved with the deregulation of cancer pathways and other human diseases. Better understanding of how these heat shock proteins work at the molecular level, which has been investigated using molecular docking tools, will give more clues about biological function. Simulating the formation and function of Hsp70 based chaperone complexes could provide …

Deconstructing Chaos: The Role Of Pitch Hierarchy In Music Perception, Gabrielle Stetz

Student Scholar Symposium Abstracts and Posters

During the early twentieth century, art music composers pushed Western tonality to the limits and eventually abandoned tonality altogether, creating a system that treated every pitch equally. This atonal system broke down all keys and harmonic progressions that are cornerstones of Western musical pitch hierarchy. Through an extensive review of current literature, this research aims to show that the concept of hierarchy, present in tonal but not atonal music, is central to music perception. This presentation will explore the role hierarchy in music perception through several means: examining the physical nature of sound on a mathematical basis, determining innate structures …

Engineered Plga Nanoparticles For Delivery Of Sirna In Mcf-7 Breast Cancer Cells, Sydney Pong, Samit Shah, Vivek Gupta

Student Scholar Symposium Abstracts and Posters

Small interfering RNAs have been an emerging medical treatment for molecular based diseases as they are capable of gene-specific knockdown. Appropriate and efficient delivery remains one of the biggest challenges in the development of siRNA as an anti-cancer treatment. Nanoparticles containing siRNA were characterized and the efficacy of various peptides in the transfection of the nanoparticles were tested. A gene silencing assay was developed in order to determine the effect of siRNA therapeutics on gene functionality in breast cancer cells.

How The Presence Of Plastic In The North Pacific Gyre Affects The Growth Of Thalassiosira Through Remote Sensing And Laboratory Replication, Jordynn Brennan, Hesham El-Askary

Student Scholar Symposium Abstracts and Posters

Through the use of remote sensing, we are able to determine the approximate location of the garbage patch in the North Pacific Gyre. Though remote sensing does not penetrate the surface of the ocean, monthly satellite images can be analyzed to determine the rate of growth or rate of decrease of certain parameters, such as atmospheric gases, phytoplankton, and dissolved organic matter. Over the past decade, data from the Goddard Earth Sciences Data and Information Services Center (Giovanni program) has shown a significant increase in dissolved organic matter and chlorophyll a content in the area of the North Pacific Garbage …

Assessment Of The Effects Of Caffeine, Gallic Acid, And Epigallocatechin-3-Gallate On Cell Inhibition, Pim-3 And E. Cadherin Protein Levels In Two Lines Of Pancreatic Cancer Cells, Lena Haddad, Melissa Rowland-Goldsmith

Student Scholar Symposium Abstracts and Posters

According to the American Cancer Society, pancreatic cancer is currently the fourth leading cause of cancer related deaths in the United States. In addition to being an exceptionally aggressive form of cancer, it is particularly difficult to treat because it is usually diagnosed in late stages after the onset of metastasis (1). Consequently, the current treatments used, including chemotherapy and radiation, have been rendered ineffective (2). As a result, focus has been placed on using dietary alternatives which are known to possess chemopreventive properties (3). Previous studies have indicated that Gallic acid (an important phytochemical in pomegranates) and Epigallocatechin-3-Gallate (the …

Distribution, Growth, And Impact Of The Coral-Excavating Sponge, Cliona Delitrix, On The Stony Coral Communities Offshore Southeast Florida, Ari Halperin

HCNSO Student Theses and Dissertations

Bioerosion is a major process that affects the carbonate balance on coral reefs, and excavating sponges from the genus Cliona are some of the most important bioeroders on Caribbean reefs. The orange boring sponge, Cliona delitrix, is an abundant excavating sponge offshore southeast Florida that frequently colonizes dead portions of live stony corals, killing live coral tissue as it grows. With the recent decline in coral cover attributed to combined environmental and anthropogenic stressors, the increasing abundance of excavating sponges poses yet another threat to the persistence of Caribbean coral reefs.

In the first part of this study, I …

Daily Eastern News: December 10, 2014, Eastern Illinois University

December

No abstract provided.

Developing A Wireless Sensor Network Programming Language Application Guide Using Memsic Devices And Labview, Xiao Xie

Master of Technology Management Plan II Graduate Projects

The principal objective of this project is to develop a wireless sensor network (WSN) programming language application guide for junior and senior undergraduate students in College of Technology, Architecture and Applied Engineering in Bowling Green State University. Memsic device, MoteWorks and LabVIEW software are used to conduct experiments in developing WSN applications after both software and hardware platform are verified to be usable with experimental and statistical analysis. The guide is divided into six chapters including both theoretical knowledge and practical experiments in WSN area. Programs, both in nesC language and LabVIEW are improved from previous work, tested to run …

Wsu Board Of Trustees Meeting Minutes, December 11-12, 2014

Board of Trustees Minutes

Minutes from the Wright State University Board of Trustees Meeting held on December 11-12, 2014.

Bio Without Borders, Tracey Bentley

UNH Today Archive

No abstract provided.

Toxicity And Cosmesis Outcomes For Single Fraction Intra-Operative Electron Radiotherapy (Ioert) For Breast Cancer, Monica Hanna, Robert Ash, Wesley Babaran, Michele M. Carpenter, Afshin Forouzannia, Jay K. Harness, Brian Kaltenecker, Snehith Maddula, Venita Williams, Lawrence Wagman

Student Scholar Symposium Abstracts and Posters

Background: Adjuvant radiation therapy is proven to reduce local recurrence in patients with early stage breast cancer. To reduce toxicity, improve geographic accuracy, and reduce treatment time, IOERT can be utilized as an alternative to external beam radiation therapy. The study’s objective was to determine the short term toxicity and cosmesis profile of single fraction IOERT given as definitive treatment in a community setting. Materials and Methods: From Mar 2012 to Jul 2014, 84 patients (3 bilateral), ages 45-91 y.o. with stage 0-II were treated with IOERT (Mobetron, IntraOp Medical, Sunnyvale, CA). A single 21 Gy fraction was administered to …

The Non-Lethal Effects Of Climate Change On The Territoriality Of Lottia Gigantea, Tracey Gunanto, Christina Chavez, Jessica Martinez, William G. Wright

Student Scholar Symposium Abstracts and Posters

The intertidal zone has been described as ground zero for global warming. Here, the owl limpet, Lottia gigantea, adapted to the cool ocean temperatures, must withstand a few hours of baking sun during day-time low tides. This hardship is predicted to increase in frequency and severity in the future as the globe warms. Our research hypothesized that heat events compromise territorial behavior of L. gigantea. All observations and experiments were performed at Inspiration Point near Newport Beach, California. We measured the natural radiant temperature of tagged limpets during day-time low tides using a field-calibrated infrared “thermogun”. We also …

The Current Volume 25 : Issue 15, Nova Southeastern University

Student Newspapers

No abstract provided.

Molecular Insights Into Prostate Field Cancerization: Telomere Length, Egr-­‐1 Expression, And Regulation Of Mic-­‐1, Pdgf-­‐A, And Fas, Emily Frisch, Kristin Gabriel, Marco Bisoffi

Student Scholar Symposium Abstracts and Posters

The diagnosis of prostate cancer (adenocarcinoma) relies on screening for elevated prostate-specific antigen (PSA) in blood samples and on digital rectal examination (DRE). With high PSA levels and/or abnormal DRE, physicians recommend a biopsy, which often misses the location of the adenocarcinoma and results in false negatives. Previous studies have shown expression of the key transcription factor early growth response 1 (EGR-1), the pro-survival factor macrophage inhibitor cytokine 1 (MIC-1), and the growth stimulatory platelet derived growth factor A (PDGF-A) to be up-regulated in histologically normal tissues 1 centimeter adjacent to prostate adenocarcinomas. We hypothesize that tumors emerge from “field …

Post Obama: Discrimination Toward African Americans Remains A Major Problem In America, Mackenzie Carl

Student Scholar Symposium Abstracts and Posters

This paper explores the issue of racial views within the United States, particularly after the election and reelection of Barack Obama in 2008 and 2012. The goal of this project is to determine if racial tension and resentment has either increased or decreased due to the election of a black President as well as determining if party identification is a predictor of racial resentment. By delving into the scholarly literature as well as looking into the public’s opinion, it is revealed that racial tension and resentment has actually increased within America, especially within the white population. Different forms of racism …

Sting, Carry And Stock: How Corpse Availability Can Regulate De-Centralized Task Allocation In A Ponerine Ant Colony, Thomas Schmickl, Istvan Karsai

ETSU Faculty Works

We develop a model to produce plausible patterns of task partitioning in the ponerine ant Ectatomma ruidum based on the availability of living prey and prey corpses. The model is based on the organizational capabilities of a "common stomach" through which the colony utilizes the availability of a natural (food) substance as a major communication channel to regulate the income and expenditure of the very same substance. This communication channel has also a central role in regulating task partitioning of collective hunting behavior in a supply&demand-driven manner. Our model shows that task partitioning of the collective hunting behavior in E. …

The Role Of Mate Preference And Personality On Reproductive Performance In An Ex-Situ Conservation Breeding Program For The Giant Panda (Ailuropoda Melanoleuca), Meghan S. Martin

Dissertations and Theses

Successful captive-breeding and re-introduction programs must have the ability to breed a surplus of genetically suitable animals for release into the wild. Unfortunately, many individuals in captive breeding programs often do not reproduce even when they are apparently healthy and presented with genetically appropriate mates. Mate choice can affect multiple parameters of reproductive sperformance, including mating success, offspring production, survival, and fecundity. We investigated the role of mate preference and personality on the reproductive performance of male and female giant pandas (Ailuropoda melanoleuca) as measured by intromission success and litter production. We conducted these studies on giant pandas at the …

How Do Administrators Of New York City Early Intervention Programs Conceptualize And Implement Family-Centered Care?, Jennifer M. Longley

Seton Hall University Dissertations and Theses (ETDs)

Family-centered care, the mandated delivery approach outlined under the Individuals with Disabilities Education Act, Part C, is considered best practice in providing services to families with children under three with special needs. It has been shown to benefit children and families through numerous positive outcomes. Yet, family-centered care is not implemented in all programs universally, and significant variation exists in how programs deliver family-centered services, to the detriment of families. Much of that variation can be attributed to programmatic leadership, as administrators establish the philosophy, policies, practices, and organizational climate of an agency.

This project intended to build on the …

Prostate Field Cancerization -- Thinking Outside The Tumor, Dor Shoshan, Marco Bisoffi

Student Scholar Symposium Abstracts and Posters

Prostate field cancerization (or field effect) is characterized by the presence of molecular alterations in histologically normal tissues adjacent to adenocarcinomas. Accordingly, our research indicates deregulated expression of several proteins that define this type of molecular pathology. The scope of the present study was to determine the expression of the key transcription factor and potential marker of field cancerization early growth response 1 (EGR-1) in human prostate tissues derived from prostatectomies and biopsy cores.

EGR-1 was detected by immunofluorescence using a polyclonal anti-human EGR-1 and Alexa Fluor 488-conjugated secondary antibodies. EGR-1 expression was quantitated by determining the pixel count per …

Effects Of Training Datasets On Both The Extreme Learning Machine And Support Vector Machine For Target Audience Identification On Twitter, Siaw Ling Lo, David Cornforth, Raymond Chiong

Research Collection School Of Computing and Information Systems

The ability to identify or predict a target audience from the increasingly crowded social space will provide a company some competitive advantage over other companies. In this paper, we analyze various training datasets, which include Twitter contents of an account owner and its list of followers, using features generated in different ways for two machine learning approaches - the Extreme Learning Machine (ELM) and Support Vector Machine (SVM). Various configurations of the ELM and SVM have been evaluated. The results indicate that training datasets using features generated from the owner tweets achieve the best performance, relative to other feature sets. …

Informing Systems, Interventions, And Innovations, William Francis Murphy Jr.

USF Tampa Graduate Theses and Dissertations

The goal of this dissertation is to not only explain the informing system discipline, but to explore cases from the perspective of the basic tenants of informing systems. The first essay explains what informing science is, the need for a transdiscipline, the channels of the Informing Science Institute informing system, and describes the clients of the ISI. The first essay ends with an analysis of the authors, institutions, and countries of origin for every ISI paper published between 1998 and 2009, as well as reporting interviews with the Editor-In-Chiefs of each ISI journal. The second essay investigates a case study …

Online Learning On Incremental Distance Metric For Person Re-Identification, Yuke Sun, Hong Liu, Qianru Sun

Research Collection School Of Computing and Information Systems

Person re-identification is to match persons appearing across non-overlapping cameras. The matching is challenging due to visual ambiguities and disparities of human bodies. Most previous distance metrics are learned by off-line and supervised approaches. However, they are not practical in real-world applications in which online data comes in without any label. In this paper, a novel online learning approach on incremental distance metric, OL-IDM, is proposed. The approach firstly modifies Self-Organizing Incremental Neural Network (SOINN) using Mahalanobis distance metric to cluster incoming data into neural nodes. Such metric maximizes the likelihood of a true image pair matches with a smaller …

The Role Of Trace Elements (Zinc, Copper, Magnesium And Calcium) In Pregnant Women With Preeclampsia In Third Trimester And Fetal Cord Blood After Delivery, Basima Sh. Alghazali, Alaa Mohammed Sadiq

Muthanna Medical Journal

Trace element such as zinc and copper display antioxidant activity and act as peroxynitratescavenger while others such as magnesium and calcium essential micronutrients. The aim of thisstudy to determine the status of these elements in preeclamptic pregnant women and to find anyrelationship between changes in serum level of zinc, copper, magnesium and calcium inpreeclamptic women and healthy women and to assess the relation to severity of the disease in AlNajef city. The patients included in this study were divided into two groups control group who are normotensive (50) and study group who are preeclampsia (50 patients, 31 mild preeclampsia and …

From The Gas, Congratulations, Publications, And Presentations, Teresa S. Welsh

SLIS Connecting

Meet the new SLIS GAs, and all about what our alum, students, and faculty have been doing.

Structural And Hydrological Controls On The Development Of A River Cave In Marble (Tapagem Cave - Se Brazil), William Sallun Filho, Bruna Medeiros Cordeiro, Ivo Karmann

International Journal of Speleology

Tapagem Cave (or Devil’s Cave) is a river cave developed in the dolomite marble karst of the Serra do André Lopes (State of São Paulo, southeastern Brazil). Although this region is a plateau with significant variation in elevation and a humid subtropical climate, the cave is an anomalous feature in the André Lopes karst because there are few other caves. The marble, which is in a synclinal structure with subjacent phyllites, is a karst aquifer perched above the regional base level (Ribeira River) and has little allogenic recharge. The cave developed on a secondary anticline on the northwest flank of …

First Opinion: Baby They Were Born To Run, Helene Halstead

First Opinions, Second Reactions

No abstract provided.

Speleoclimate Dynamics In Santana Cave (Petar, São Paulo State, Brazil): General Characterization And Implications For Tourist Management, Heros Augusto Santos Lobo, Paulo Cesar Boggiani, José Alexandre De Jesus Perinotto

International Journal of Speleology

Show caves provide tourists with the opportunity to have close contact with natural underground spaces. However, visitation to these places also creates a need for management measures, mainly the definition of tourist carrying capacity. The present work describes the results of climate monitoring and atmospheric profiling performed in Santana Cave (Alto Ribeira State and Tourist Park – PETAR, Brazil) between 2008 and 2011. Based on the results, distinct preliminary zones with different levels of thermal variation were identified, which classify Santana Cave as a warm trap. Two critical points along the tourist route (Cristo and Encontro Halls) were identified where …

Characterization Of Corneal Biomechanics Using Customized Atomic Force Microscopy Techniques, Janice Maxine Dias

Open Access Dissertations

Corneal biomechanics has become an increasingly important field within ophthalmology. Striving to establish a relationship between corneal physiological structure and function, corneal biomechanics is an objective, quantitative measure that aids in the development and improvement of diagnostic and therapeutic methods for corneal-related diseases. The goal of this project was to advance the technology of Atomic Force Microscopy (AFM) as a suitable characterization technique within the field of corneal biomechanics. The studies of this project include the development of AFM instrumentation, experimental techniques, and models to measure the elastic, viscoelastic, and poroelastic properties of the cornea in situ. Such developed instrumentation, …