Digital Commons Network^™

The Role Of The Oxidative Stress Product Carboxyethylpyrrole In Innate Immunity, Ali M. Saeed

Open Access Dissertations

Oxidative-stress is key in the pathogenesis of several diseases and the general aging process. Molecular targets of oxidative stress include nucleic acids, proteins, and lipids. It has previously been established that a particular lipid peroxidation product, carboxyethylpyrrole (CEP), accumulates in melanoma, autistic brain tissue, atherosclerotic plaques, sites undergoing wound healing, and in the retinas of AMD patients. The role of CEP is best characterized in AMD and in addition to the retina, elevated levels of CEP and autoantibodies against CEP are found in the sera of AMD patients (versus age-matched controls). Our previous studies have demonstrated CEP as a potential …

An Investigation Into The Survival Of Submerged Prehistoric Cultural Resources In Florida Bay, Everglades National Park, Leah Grace Colombo

Open Access Theses

Submerged prehistoric archaeological material exists on the continental shelf in Florida. Florida Bay is a shallow marine body of water located between the Florida Peninsula and the Florida Keys. Previously, no attempts have been made to locate such material in Florida Bay, Everglades National Park. This National Park Service funded study was initiated to develop a method to quantify submerged prehistoric cultural resources that may be harmed by world sea level rise and regional anthropogenic changes. No technology now exists to remotely sense prehistoric archaeological material, thus this investigation involved first the development of a predictive model. This included an …

Competitive Replacement Of Invasive Congeners May Relax Impact On Native Species: Interactions Among Zebra, Quagga, And Native Unionid Mussels, Lyubov E. Burlakova, Brianne L. Tulumello, Alexander Y. Karatayev, Robert A. Krebs, Donald W. Schloesser, Wendy L. Paterson, Traci A. Griffith, Mariah W. Scott, Todd Crail, David T. Zanatta

Biological, Geological, and Environmental Faculty Publications

Determining when and where the ecological impacts of invasive species will be most detrimental and whether the effects of multiple invaders will be superadditive, or subadditive, is critical for developing global management priorities to protect native species in advance of future invasions. Over the past century, the decline of freshwater bivalves of the family Unionidae has been greatly accelerated by the invasion of Dreissena. The purpose of this study was to evaluate the current infestation rates of unionids by zebra (Dreissena polymorpha) and quagga (D. rostriformis bugensis) mussels in the lower Great Lakes region 25 …

Pseudomonas Syringae Type Iii Effectors: Targets And Roles In Plant Immunity, Tania Y. Toruño

Center for Plant Science Innovation: Faculty Publications

Pseudomonas syringae is a Gram-negative bacterial pathogen that infects many crops. A central virulence strategy P. syringae uses to successfully infect plants is the injection of type III effector proteins (T3Es) into plant cells through a type IIII protein secretion system (T3SS). The T3SS is a molecular syringe found in many Gram-negative bacterial pathogens of plants and animals that transport T3Es from the bacterial cytosol into eukaryotic cells. T3Es disrupt host processes in the plant immune system required to restrict pathogen ingress. The plant innate immune system is divided in two branches, pathogen-associated molecular patterns (PAMP)-triggered immunity (PTI) and effector-triggered …

December 9, 2014 Finance & Facilities (F&F) Committee Meeting, Evp For Administration

Finance and Facilities Committee

Documents related to the December 9, 2014 Board of Regents' Finance and Facilities Committee Meeting. (Agenda, Minutes, eBook, Notice)

Assessment Of Macroinvertebrate Communities And Heavy Metal Contamination Along The Intracoastal Waterway In Fort Lauderdale, Florida, Robert Bernhard

HCNSO Student Theses and Dissertations

Sediments from four areas adjacent to marinas and a background site in the Intracoastal Waterway were assessed for macroinvertebrate composition and heavy metal contamination. Sediment core samples were collected in 2004 and 2005 for analyses of macroinvertebrate composition and sediment grain size. Additional sediment samples were collected in 2005 for chemical analyses of metals (Al, As, Cd, Cr, Cu, Fe, Pb, Hg, Ni and Zn). MANOVA and dendograms using Bray-Curtis similarity matrices grouped the sites into two clusters: the 3 sites closest to the New River formed one group, and the two end sites formed the other. The sites nearest …

Electrochemical Synthesis Of Nanostructured Noble Metal Films For Biosensing, Jay Kishan Bhattarai

Dissertations

Nanostructures of noble metals (Au and Ag) are of interest because of their important intrinsic properties. Noble metals by themselves are conductive, physically robust, chemically inert, and strongly bind to thiols. However, when the nanostructures are formed, they in addition possess high surface area and unique optical properties tunable by adjusting the shape and size. All of these properties make nanostructures of noble metals suitable candidates to be used as a transducer for biosensing. Individual nanostructures might be easier to prepare but difficult to handle to be used as a transducer. Therefore, we prepared and analyzed nanostructured films/coating of noble …

Daily Eastern News: December 09, 2014, Eastern Illinois University

December

No abstract provided.

White-Nose Syndrome Initiates A Cascade Of Physiologic Disturbances In The Hibernating Bat Host, Michelle L. Verant, Carol U. Meteyer, John R. Speakman

KIP Articles

The physiological effects of white-nose syndrome (WNS) in hibernating bats and ultimate causes of mortality from infection with Pseudogymnoascus (formerly Geomyces) destructans are not fully understood. Increased frequency of arousal from torpor described among hibernating bats with late-stage WNS is thought to accelerate depletion of fat reserves, but the physiological mechanisms that lead to these alterations in hibernation behavior have not been elucidated. We used the doubly labeled water (DLW) method and clinical chemistry to evaluate energy use, body composition changes, and blood chemistry perturbations in hibernating little brown bats (Myotis lucifugus) experimentally infected with P. destructans to better understand …

Flyer News, Vol. 62, No. 13 (Dec. 9, 2014), University Of Dayton

Flyer News

Student-run newspaper of the University of Dayton.

Not Just A Theory--The Utility Of Mathematical Models In Evolutionary Biology, Maria R. Servedio, Yaniv Brandvain, Sumit Dhole, Courtney L. Fitzpatrick, Emma E. Goldberg, Caitlin A. Stern, Jeremy Van Cleve, D. Justin Yeh

Biology Faculty Publications

Progress in science often begins with verbal hypotheses meant to explain why certain biological phenomena exist. An important purpose of mathematical models in evolutionary research, as in many other fields, is to act as “proof-of-concept” tests of the logic in verbal explanations, paralleling the way in which empirical data are used to test hypotheses. Because not all subfields of biology use mathematics for this purpose, misunderstandings of the function of proof-of-concept modeling are common. In the hope of facilitating communication, we discuss the role of proof-of-concept modeling in evolutionary biology.

Methods And Compositions For Improving Bioavailability Of Epigallocatechin Gallate (Egcg), Roland Douglas Shytle, Jun Tan, Adam Smith, Brian Giunta, Cyndy Davis Sanberg

USF Patents

Compositions and methods of increasing the bioavailability of catechins are presented. Compositions for increasing the bioavailability of catechins include compositions where the catechin is added to a solution of ethanol and water; compositions where the catechin is encapsulated within a nanoparticle; and compositions in which a nanoparticle complex is formed between the catechin and the nanoparticle. Each of these compositions was shown to increase bioavailability of EGCG and is useful in treating diseases such as Alzheimer's and HIV-associated dementia.

Effective Treatment Of Ovarian Cancer Using Triciribine And Related Compounds, Jin Q. Cheng

USF Patents

The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat ovarian cancer by one or a combination of (i) administering triciribine only to patients which according to a diagnostic test described below, exhibit enhanced sensitivity to the drug; (ii) use of a described dosage level that minimizes the toxicity of the drug but yet still exhibits efficacy; or (iii) use of a described dosage regimen that minimizes the toxicity of the drug. The invention further encompasses a number of miRNAs, which are altered in human ovarian cancer, with the most significantly deregulated …

Methods And Materials For Increasing Potency Of Cells (Con 1), Kiminobu Sugaya, Angel Alvarez

UCF Patents

Disclosed herein are methods and materials for producing a more developmentally potent cell from a less developmentally potent cell. Specifically exemplified herein are methods that comprise introducing an expressible dedifferentiating polynucleotide sequence into a less developmentally potent cell, wherein the transfected less developmentally potent cell becomes a more developmentally potent cell capable of differentiating to a less developmentally potent cell of its lineage of origin or a different lineage.

The Sun Star Vol 34 No 14 (December 9th, 2014), N/A N/A

Sun Star

No abstract provided.

Recruitment Patterns Of The Fouling Community On Eelgrass In Long Island Sound, Diana Lancaster

Master's Theses

The seagrass Zostera marina (eelgrass) is typically found in shallow protected areas of portions of eastern Long Island Sound (LIS). Although the species and its associated ecosystem have been well studied in many places, work in LIS has been limited. A field study was conducted to assess the fouling communities associated with eelgrass beds around Pine Island, in eastern LIS. Samples were collected from four sites between July and October, 2011. A total of 15 species of fouling organisms were found on eelgrass leaves throughout the study period. Recruitment patterns varied spatially and temporally. Differences in the composition of fouling …

Getting Down To The Fundamentals Of Hydrogen Bonding: Anharmonic Vibrational Frequencies Of (Hf)2 And (H2o)2 From Ab Initio Electronic Structure Computations, J. Coleman Howard, Jessica L. Gray, Amanda J. Hardwick, Linh T. Nguyen, Gregory S. Tschumper

Chemistry Faculty Research & Creative Works

This work presents a systematic investigation into the basis set convergence of harmonic vibrational frequencies of (H₂O)₂ and (HF)₂ computed with second-order Møller-Plesset perturbation theory (MP2) and the coupled-cluster singles and doubles method with perturbative connected triples, CCSD(T), while employing correlation-consistent basis sets as large as aug-cc-pV6Z. The harmonic vibrational frequencies presented here are expected to lie within a few cm^-1 of the complete basis set (CBS) limit. For these important hydrogen-bonding prototype systems, a basis set of at least quadruple-ζ quality augmented with diffuse functions is required to obtain harmonic vibrational frequencies within 10 …

Jackson V. State Appellant's Brief Dckt. 42116

Not Reported

No abstract provided.

Nanopulse Generators: Their Design And Application To Cancer Therapy Studies, Daniel P. Wernig

Senior Honors Theses

Effective nanopulse generators have become critical in recent decades concerning the study of subcellular affects in response to nanosecond pulsed electric fields. It has been observed that nanosecond duration electric pulses can target intracellular organelles, ultimately leading to cell apoptosis, suggesting the possibility of a new, minimally invasive, low risk cancer therapy methodology. The standard topology for developing a medical nanopulser is the Blumlein “transmission line” approach. This approach relies on the nearly infinitesimal, yet finite amount of time required for an electromagnetic field to propagate down a short transmission line. Prior to design, requirements and constraints must be defined …

Tightening The Reins On Single-Sex Classes In Public Schools, Joanna L. Grossman

Hofstra Law Faculty Scholarship

The Department of Education’s Office for Civil Rights (OCR) just issued a much-needed clarification of its prior guidance on the legality of single-sex classes within public schools. A clarification of a guidance of a law may seem like the epitome of bureaucratic mumbo jumbo, but, in this case, the clarification was needed to halt a runaway train—single-sex classes being implemented in public schools around the country in clear violation of existing law and designed in ways more likely to create gender inequality than eradicate it.

Subtropical Atlantic Climate Variability Record In Speleothems From The Bahamas, Monica Arienzo

Open Access Dissertations

The last 100,000 years of climate consist of numerous abrupt millennial scale climate variations. Of interest to this study are Heinrich stadials which are extreme cold events in the North Atlantic. While a comprehensive picture of climate across Heinrich events is emerging for the North Atlantic, very few studies have been conducted in the subtropical western Atlantic, which may be important for the global propagation of these events. This study is the first study to determine paleoclimate of the Bahamas across Heinrich stadials. Cave deposits, in particular stalagmites, offer the opportunity to obtain high resolution records of past climate. Typically, …

Person To Person In Germany, Andrea Pakula

2014-15 Field Notes

While still in the midst of their study abroad experiences, students at Linfield College write reflective essays. Their essays address issues of cultural similarity and difference, compare lifestyles, mores, norms, and habits between their host countries and home, and examine changes in perceptions about their host countries and the United States. In this essay, Andrea Pakula describes her observations during her study abroad program at Nürtingen-Geislingen University in Nürtingen, Germany.

Climate Change And Stream Temperature Projections In The Columbia River Basin: Habitat Implications Of Spatial Variation In Hydrologic Drivers, Darren L. Ficklin, B. L. Barnhart, J. H. Knouft, Iris T. Stewart-Frey, Edwin P. Maurer, Sally L. Letsinger, G. W. Whittaker

Civil, Environmental and Sustainable Engineering

Water temperature is a primary physical factor regulating the persistence and distribution of aquatic taxa. Considering projected increases in air temperature and changes in precipitation in the coming century, accurate assessment of suitable thermal habitats in freshwater systems is critical for predicting aquatic species' responses to changes in climate and for guiding adaptation strategies. We use a hydrologic model coupled with a stream temperature model and downscaled general circulation model outputs to explore the spatially and temporally varying changes in stream temperature for the late 21st century at the subbasin and ecological province scale for the Columbia River basin (CRB). …

12-08-2014 Swosu Students To Graduate In December, Southwestern Oklahoma State University

THE BARK ARCHIVE 2014

Approximately 313 students from Southwestern Oklahoma State University at Weatherford will complete requirements for either associate’s, bachelor’s, master’s or doctoral degrees after the current Fall 2014 semester.

The Objectification Of Professional Female Athletes In Print Advertisements And The Consumers' Response, Angela L. Wallin

Sport Management Undergraduate

Abstract

As female athletes gain more recognition in the sports world, researchers continuously debate on whether the reason behind this is due to their athletic performance or their hyper sexualized appearance in media outlets such as print advertisements (Fink, Cunningham, & Kensicki, 2004). This raises the question on how consumers interpret advertisements that contain female athletes promoting both sport and non-sport products. Since this research is the first examine how consumers view and react to the use of professional female athletes in advertisements, this research further develops the literature of women’s role in both the advertising and sport world. Both …

A Microstructural Constitutive Framework For Injured Ligament, Christina J. Stender, Evan Rust, Raquel J. Brown, Trevor J. Lujan

Biomedical Research Institute Student Presentations

No abstract provided.

The Statesman, V. 58, I. 15, Stony Brook University

Stony Brook Statesman-Sucolian

v. 58, i. 15

Current, December 08, 2014, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

Quality Change And Thermal Inactivation Of Escherichia Coli O157:H7 In Non-Intact Beef And Veal Patties By Double Pan-Broiling, Kawang Li

Mahurin Honors College Capstone Experience/Thesis Projects

Escherichia coli O157:H7 (ECOH) may translocate from meat surfaces to internal tissues during grinding processes. This study evaluated the inactivation of ECOH in ground beef and veal by cooking to various internal temperatures (55°C, 62.5°C, 71.1°C, and 76°C). Grounded beef/veal were inoculated with 6 log ECOH and prepared into patties, stored aerobically (4°C, 4 -days) before double-pan-broiling to the internal temperatures mentioned above with a three-minute rest. Samples’ color were monitored, which changed significantly during storage and cooking. Pathogen concentration was measured by plating the homogenized sample on TSA and McConkey agar. The pathogen population was below detectable limit when …

Reaction Rates Of Amino Acids With Derivatives Of The Anticancer Drug Cisplatin, Celia Jess Whelan

Mahurin Honors College Capstone Experience/Thesis Projects

We are studying reactions of cisplatin derivatives, which differ in both size and shape, with various amino acids. When reaction with DNA occurs, apoptosis is observed, ideally leading to termination of the cancer. Due to the affinity of cisplatin for sulfur-containing amino acids, reaction with proteins may occur prior to access to the DNA, producing a large array of products, which could potentially be toxic to the human body. Both the size and shape of the platinum complexes often affect the reactions with protein targets more so than with DNA targets. By performing reactions of specific amino acids targets with …