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09-04-2014 Parent's Day Activities Planned September 13 At Swosu, Southwestern Oklahoma State University

THE BARK ARCHIVE 2014

A wide variety of Parent's Day activities are planned for Saturday, September 13, at Southwestern Oklahoma State University in Weatherford.

Transcriptional Profiles Of Bovine In Vivo Pre-Implantation Development, Zongliang Jiang, Jiangwen Sun, Hong Dong, Oscar Luo, Xinbao Zheng, Craig Obergfell, Yong Tang, Jinbo Bi, Rachel O'Neill, Yijun Ruan, Jingbo Chen, Xiuchun Tian

Faculty Publications

© 2014 Jiang et al.; licensee BioMed Central Ltd. Background: During mammalian pre-implantation embryonic development dramatic and orchestrated changes occur in gene transcription. The identification of the complete changes has not been possible until the development of the Next Generation Sequencing Technology.Results: Here we report comprehensive transcriptome dynamics of single matured bovine oocytes and pre-implantation embryos developed in vivo. Surprisingly, more than half of the estimated 22,000 bovine genes, 11,488 to 12,729 involved in more than 100 pathways, is expressed in oocytes and early embryos. Despite the similarity in the total numbers of genes expressed across stages, the nature of …

A Troublesome Inheritance': Nicholas Wade’S Botched Interpretation Of Human Genetics, History, And Evolution, Agustin Fuentes

Human Biology Open Access Pre-Prints

Review of A Troublesome Inheritance: Genes, Race and Human History, by Nicholas Wade. New York: Penguin Press, 2013. x + 278 pp. 978-1-5942-0446-3 (hardcover). US $27.95.

Sequence-Based Antigenic Change Prediction By A Sparse Learning Method Incorporating Co-Evolutionary Information., Jialiang Yang, Tong Zhang, Xiu-Feng Wan

CVM Publications

Rapid identification of influenza antigenic variants will be critical in selecting optimal vaccine candidates and thus a key to developing an effective vaccination program. Recent studies suggest that multiple simultaneous mutations at antigenic sites accumulatively enhance antigenic drift of influenza A viruses. However, pre-existing methods on antigenic variant identification are based on analyses from individual sites. Because the impacts of these co-evolved sites on influenza antigenicity may not be additive, it will be critical to quantify the impact of not only those single mutations but also multiple simultaneous mutations or co-evolved sites. Here, we developed and applied a computational method, …

Thermal Niche Evolution And Geographical Range Expansion In A Species Complex Of Western Mediterranean Diving Beetles., Amparo Hidalgo-Galiana, David Sánchez-Fernández, David T. Bilton, Alexandra Cieslak, Ignacio Ribera

School of Biological and Marine Sciences

BACKGROUND: Species thermal requirements are one of the principal determinants of their ecology and biogeography, although our understanding of the interplay between these factors is limited by the paucity of integrative empirical studies. Here we use empirically collected thermal tolerance data in combination with molecular phylogenetics/phylogeography and ecological niche modelling to study the evolution of a clade of three western Mediterranean diving beetles, the Agabus brunneus complex. RESULTS: The preferred mitochondrial DNA topology recovered A. ramblae (North Africa, east Iberia and Balearic islands) as paraphyletic, with A. brunneus (widespread in the southwestern Mediterranean) and A. rufulus (Corsica and Sardinia) nested …

Histone Methyltransferase Mmset/Nsd2 Alters Ezh2 Binding And Reprograms The Myeloma Epigenome Through Global And Focal Changes In H3k36 And H3k27 Methylation, Relja Popovic, Eva Martinez-Garcia, Eugenia G. Giannopoulou, Quanwei Zhang, Qingyang Zhang, Teresa Ezponda, Mrinal Y. Shah, Yupeng Zheng, Christine M. Will, Eliza C. Small, Youjia Hua, Marinka Bulic, Yanwen Jiang, Matteo Carrara, Raffaele A. Calogero, William L. Kath, Neil L. Kelleher, Ji-Ping Wang, Olivier Elemento, Jonathan D. Licht

Publications and Research

Overexpression of the histone methyltransferase MMSET in t(4;14)+ multiple myeloma patients is believed to be the driving factor in the pathogenesis of this subtype of myeloma. MMSET catalyzes dimethylation of lysine 36 on histone H3 (H3K36me2), and its overexpression causes a global increase in H3K36me2, redistributing this mark in a broad, elevated level across the genome. Here, we demonstrate that an increased level of MMSET also induces a global reduction of lysine 27 trimethylation on histone H3 (H3K27me3). Despite the net decrease in H3K27 methylation, specific genomic loci exhibit enhanced recruitment of the EZH2 histone methyltransferase and become hypermethylated on …

The Montclarion, September 04, 2014, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

Biofeedback Relaxation Techniques In Addressing Cortex-Hypothalamus Control Loop For Motivation Of Obesity Avoidance, Liljana Bozinovska, Ahmed Majekodunmi

Professional Agricultural Workers Journal

This research explores how the achievement motivation pathway in the cortex influences hypothalamic activity, which could influence appetite control and obesity avoidance. The objective was to examine the sympathetic/parasympathetic feedback loop, and the influence of various biofeedback relaxation techniques on lowering heart rate (HR) and electrodermal activity (EDA). The methodology used was a standard biofeedback mechanism with visual representation of the measured physiological parameters. The feedforward part of the said feedback loop is controlled by hypothalamus while the feedback part is evaluated by the cortex. The participants were young adults and the sample size was ten. The results revealed that …

Fermented Food: Putting The Power Of Good Health Back Into The Hands Of The People, Marsha L. Thadison

Professional Agricultural Workers Journal

Editors’ Note: At the December 2013 Professional Agricultural Workers Conference, several women were invited to share, information about their unique businesses. One such presenter was Marsha L. Thadison, owner of Yesterday’s Kitchen 4 Today, a company that focuses on promoting functional foods. Thadison shared that food is produce and consumed differently from previous generations. Today's food, she argued, involves many more agricultural inputs that aid in food preservation, extension of shelf life, and promotion of animal health. She espoused the benefits of fermented food.

Skin Cancer Risk Perception And Sunscreen Use In Adolescent Female Soccer Athletes, Cheryl L. Butera Phd, Msn, Aprn, Fnp-Bc, Np-C, Phn

Dissertations

Over 3.5 million cases of skin cancer are diagnosed annually in the United States. In adolescent females ages 15-19, melanoma is the second most common form of cancer. The greatest risk factor for skin cancer is ultraviolet rays from the sun. Research has shown that sunscreen use is protective of all skin cancers, especially melanoma. The purpose of this study was to obtain perceptions about risk of skin cancer and sunscreen use among 13- to 18-year-old adolescent female club soccer athletes as a basis for effective interventions to improve sunscreen use in this population. The Health Belief Model was employed …

The Significance Of Dynamical Architecture For Adaptive Responses To Mechanical Loads During Rhythmic Behavior, Kendrick M. M. Shaw, David N. Lyttle, Jeffrey P. Gill, Miranda J. Cullins, Jeffrey M. Mcmanus, Hui Lu, Peter J. Thomas, Hillel J. Chiel

Faculty Scholarship

Many behaviors require reliably generating sequences of motor activity while adapting the activity to incoming sensory information. This process has often been conceptually explained as either fully dependent on sensory input (a chain reflex) or fully independent of sensory input (an idealized central pattern generator, or CPG), although the consensus of the field is that most neural pattern generators lie somewhere between these two extremes. Many mathematical models of neural pattern generators use limit cycles to generate the sequence of behaviors, but other models, such as a heteroclinic channel (an attracting chain of saddle points), have been suggested. To explore …

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Moth Project to Attract ‘Second-Shift Pollinators’ on Campus

The Inkwell, Armstrong State University

The Inkwell

No abstract provided.

Full Issue

Colby Magazine

Colby Magazine vol. 103, no. 1 (Summer 2014): full issue

Obituaries

Colby Magazine

No abstract provided.

Class Notes

Colby Magazine

No abstract provided.

Media

Colby Magazine

The Kid: The Immortal Life of Ted Williams, by Ben Bradlee Jr. '70

The Hotel on Place Vendome, by Tilar Mazzeo (English)

The Long Struggle Against Malaria in Tropical Africa, by James L.A. Webb Jr. (History)

Freeing the Hook, by Peter Harris (English)

The L Word, by Margaret McFadden (American Studies)

The Conquest of the Russian Arctic, by Paul R. Josephson (History)

Fort Halifax: Winslow's Historic Outpost, by Daniel Tortora (History)

More Dam Trouble, by Earl H. Smith (College historian)

Parallel Universe, by Arthur Levering '76

Graduate to a Great Job, by David DeLong '73

Travis J. Carter (Psychology)

Jennifer …

Shorter Takes (Short Form)

Colby Magazine

On Wescott's Death- and Exemplary Life

Church Forest Study Lands NSF Grant

The True Meaning of the Super Bowl

To Your Health, By the Numbers

Under New Management

Peanut Butter in Cereal?
Amila Emso, Turkey
Byoungwook Jang, Korea
Kimara Nzamubona, Congo
Miia-Liisa Termonen, Finland
Ricah Kunde, Germany
Guga Gogia, Georgia

"I went up to him and I said, 'You are a very discreet man.'"

William D. Adams Gallery? Surprise!

Warm and Fuzzy? Maybe This Last Time

Sunny Day for Shining Stars

Colby Bench Makes Final Four

Work Hard, Present Well

Arendell, Marlais, and Reich Retire from Teaching Faculty

In The Kitchen With Andy King '99, Gerry Boyle

Colby Magazine

Colby's academics helped baker Andy King '99 master his craft.

Nsf Bets Big On David Angelini, Gerry Boyle

Colby Magazine

Something has been bugging Colby geneticist David Angelini.

How, Angelini wonders, can a single species (in this case the soapberry bug) produce two distinctly different forms, one with long wings and one with short, that are not linked to sex? What is the genetic mechanism that causes the wings to develop differently?

"Why does it not overshoot the long form? he asked. "Why doesn't it undershoot the short form? Why doesn't it end up somewhere in the middle? That's an open question."

And a question that the National Science Foundation wants him to answer.

David Greene Is Called To Action, Ruth Jacobs

Colby Magazine

Not long after the Board of Trustees named David A. Greene Colby's 20th president, in September 2013, word spread that Greene wanted to increase the number of applicants- by a lot. Doubling applications, which he suggested, would be a dramatic shift for a college that typically sees single-digit growth in applications.

The University of Chicago, where Greene recently served as executive vice president, has tripled its number of applicants since Greene's (and President Robert Zimmer's) arrival in 2006, resulting in a more diverse student body by key measures- socioeconomic, racial, ethnic, and geographic. It has also soared in the rankings, …

Evaluation Of Natural Plant Powders With Potential Use In Antimicrobial Packaging Applications, Yujie Cheng, Changfeng Ge, Jeffrey Lodge, Ksv Santhanam, Lixing Lu

Journal of Applied Packaging Research

This study investigates the antimicrobial effects of vanillin, turmeric and curcumin in the forms of Dimethyl Sulfoxide (DMSO) solution as well as polymer packaging. Five types of common pathogens and food spoilage bacteria were used in this study: Staphylococcus aureus and Listeria monocytogenes representing gram-positive bacteria; Shigella sonnei, Salmonella typhimurium as well as E.coli O157:H7 representing gram- negative bacteria. Turmeric is chosen as the antimicrobial agent to be incorporated into packaging materials. In order to study the antimicrobial effect as packaging application, two types of the polymer based turmeric products were produced. They are LDPE based turmeric pellets produced by …

Genetic Evidence For Multiple Sources Of The Non-Native Fish Cichlasoma Urophtalmus (Günther; Mayan Cichlids) In Southern Florida, Elizabeth Harrison, Joel C. Trexler, Timothy M. Collins, Ella Vazquez-Domínguez, Ulises Razo-Mendivil, Wilfredo A. Matamoros, Christian Barrientos

Student Publications

The number and diversity of source populations may influence the genetic diversity of newly introduced populations and affect the likelihood of their establishment and spread. We used the cytochrome b mitochondrial gene and nuclear microsatellite loci to identify the sources of a successful invader in southern Florida, USA, Cichlasoma urophthalmus (Mayan cichlid). Our cytochrome b data supported an introduction from Guatemala, while our microsatellite data suggested movement of Mayan Cichlids from the upper Yucatán Peninsula to Guatemala and introductions from Guatemala and Belize to Florida. The mismatch between mitochondrial and nuclear genomes suggests admixture of a female lineage from Guatemala, …

Weekly News Digest 09/03/2014, Jenna Ray

Weekly Bulletin Archive

In this issue:

● The New Standards Open Performing Arts Series

● Campus To Welcome Nobel Laureate Dr. Peter Agre

●Morris Awarded College Success Grant for AlertPLUS

● Kuchenreuther Featured in the Minneapolis Star Tribune

Outstanding Educational Performance Awards: Highlighting High-Achieving Arkansas Schools, 2014, Charlene A. Reid, Gary W. Ritter

Arkansas Education Reports

In this report, we are presenting a list of the top 25 schools in each area. In some cases, these "top 25 lists" will contain more than 25 schools as some schools' GPA scores will be identical. This is not a new phenomenon, as we also exceeded 25 schools in previous reports when using the percent proficient and advanced metric as an indicator for student achievement; however, there are fewer ties using the more precise GPA measure.

After we present our overall snapshot of high-performing schools, we will release subsequent reports every few weeks focusing on different subsets of schools. …

Biological Activities Of Fusarochromanone: A Potent Anti-Cancer Agent, Elahe Mahdavian, Phillip Palyok, Steven Adelmund, Tara Williams-Hart, Brian D. Furmanski, Yoon-Jee Kim, Ying Gu, Mansoureh Barzegar, Yang Wu, Kaustubh N. Bhinge, Gopi K. Kolluru, Quincy A. Quick, Yong-Yu Liu, Christopher G. Kevil, Brian A. Salvatore, Shile Huang, John L. Clifford

Biology Faculty Research

Background

Fusarochromanone (FC101) is a small molecule fungal metabolite with a host of interesting biological functions, including very potent anti-angiogenic and direct anti-cancer activity.

Results

Herein, we report that FC101 exhibits very potent in-vitro growth inhibitory effects (IC₅₀ ranging from 10nM-2.5 μM) against HaCat (pre-malignant skin), P9-WT (malignant skin), MCF-7 (low malignant breast), MDA-231 (malignant breast), SV-HUC (premalignant bladder), UM-UC14 (malignant bladder), and PC3 (malignant prostate) in a time-course and dose-dependent manner, with the UM-UC14 cells being the most sensitive. FC101 induces apoptosis and an increase in proportion of cells in the sub-G1 phase in both HaCat and P9-WT …

September 3, 2014 General Faculty Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

President's Convocation (2014 Program), Illinois Wesleyan University

President’s Convocation

No abstract provided.

A Homogenizing Process Of Selection Has Maintained An 'Ultra-Slow' Acetylation Nat2 Variant In Humans, Blandine Patillon, Pierre Luisi, Estella S. Poloni, Sotiria Boukouvala, Pierre Darlu, E. Genin, Audrey Sabbagh

Human Biology Open Access Pre-Prints

N-acetyltransferase 2 (NAT2) is an important enzyme involved in the metabolism of a wide spectrum of naturally occurring xenobiotics, including therapeutic drugs and common environmental carcinogens. Extensive polymorphism in NAT2 gives rise to a wide interindividual variation in acetylation capacity which influences individual susceptibility to various drug-induced adverse reactions and cancers. Striking patterns of geographic differentiation have been described for the main slow acetylation variants of the NAT2 gene, suggesting the action of natural selection at this locus. In the present study, we took advantage of the whole-genome sequence data available from the 1000 Genomes project to investigate the …

Characterization Of Functional Domains Of Cul3, An E3 Ubiquitin Ligase, Using Chimeric Analysis, Jennifer Anne Mitchell

Dissertations and Theses

Modification of cellular proteins with molecules of ubiquitin is an important process that regulates the activity of cellular proteins. Cullin RING ligases (CRLs) are multi-subunit complexes that act in concert with E2 enzymes to attach molecules of ubiquitin to protein substrates. There are seven CRLs in mammalian cells (Cul1, Cul2, Cul3, Cul4A, Cul4B, Cul5, and Cul7) that are highly homologous in sequence and structure. CRLs possess a highly conserved C- terminal domain that interacts with E2 enzymes, and a more variable N- terminal domain which recruits substrates through distinct substrate adapter molecules. Despite the structural similarity, these CRLs recognize distinct …