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Design And Optimization Of A De Novo Protein Charge Separation Dyad, Andrew C. Mutter

Dissertations, Theses, and Capstone Projects

The ever-increasing demand for cheap, plentiful energy to fuel the needs of a growing population requires research into alternative clean energy. Solar irradiation has the potential to power the planet many times over; the challenge is efficient capture and conversion of this energy source. Nature has already solved this problem with photosynthesis, which harvests solar irradiation converting it to stored chemical energy and is the source of the energy for life. The goal of my dissertation is to use de novo designed protein to mimic the charge separation system in photosynthesis. A stable protein scaffold will be designed and used …

Kafka's German-Jewish Reception As Mirror Of Modernity, Abraham Ariel Rubin

Dissertations, Theses, and Capstone Projects

This study explores the diverse and contradictory ways German-Jewish intellectuals identify what they commonly refer to as Kafka's "Jewish essence." Focusing on the commentaries of Margarete Susman, Hans-Joachim Schoeps, Gershom Scholem, and Max Brod, I claim that Kafka's German-Jewish reception reflects a broader historical dilemma that grew out of the Jewish encounter with modernity: Are Judaism and Jewishness best defined through religious, cultural, national, or ethnic categories? It is precisely this ambiguity that forms the historical backdrop to Kafka's Jewish interpretations. Situating the early phases of Kafka's posthumous reception within the broader context of interwar German-Jewish culture, my dissertation examines …

Facial Affect Recognition And Social Functioning In Individuals At Risk For Schizophrenia Spectrum Disorders, Marta Ewa Statucka

Dissertations, Theses, and Capstone Projects

Facial affect recognition (FAR) is impaired in schizophrenia patients and to a lesser extent in individuals at familial/genetic, clinical, and psychometric risk for psychosis. Reduced FAR reaction time and negative bias are present in patients; however, their role is less clear in at-risk samples. Impaired social functioning, a hallmark of schizophrenia, is also impaired in at-risk individuals and is associated with FAR impairment. Given FAR deficits in schizophrenia, the current study aimed to elucidate the nature of FAR and social functioning impairments among individuals at high psychometric risk for psychosis and to examine whether FAR acts as a mediator in …

Redefining Diaspora Consciousness: Musical Practices Of Moroccan Jews In Brooklyn, Samuel Reuben Thomas

Dissertations, Theses, and Capstone Projects

This dissertation examines the role of musical practices in the synagogue life of Maroka'im (Moroccan Jews) in Brooklyn, New York. Living in an urban setting known for its diverse and robust Jewish life, community members utilize several different types of musical expression to emblematize three distinct diasporic ethnic identities: Jewish (of ancient Israel), Sephardi (Spanish), and Maroka'i (Moroccan). Based upon ethnographic fieldwork carried out between 2008 and 2013, this study demonstrates how Maroka'im in Brooklyn use musical expressions to evoke more than one sense of diaspora consciousness--Jewish, Sephardi, and Maroka'i--to foster what I term a layered diaspora consciousness.

To illustrate …

Fabrication And Characterization Of Sol-Gel Based Nanoparticles For Drug Delivery, Reeta Yadav

Dissertations, Theses, and Capstone Projects

Nanogels are cross linked polymeric sol-gel based nanoparticles that offer an interior network for incorporation and protection of biomolecules, exhibiting unique advantages for polymer based delivery systems. We have successfully synthesized stable sol-gel nanoparticles by means of [a] silicification reactions using cationic peptides like polylysine as gelating agents, and [b] lyophilization of sol-gels. Macromolecules such as Hemoglobin and Glucose Oxidase and small molecules such as Sodium Nitroprusside (SNP) and antibiotics were encapsulated within the nanogels. We have used transmission electron microscopy, dynamic light scattering, zeta potential analysis, and spectroscopy to perform a physicochemical characterization of the nanogels resulting from the …

Psychic Collapse And Traumatic Defense: How The Mind Mediates Trauma Living In The Body, Patricia Kim Yoon

Dissertations, Theses, and Capstone Projects

The aim of this exploratory study was to link psychoanalytic theories of trauma and its impact on the mind with psychobiological research of how trauma lives in the body. The study has expanded on prior research (Cramer, 2003) to evidence that defense mechanisms do in fact moderate the relationship between stress and physiological response, and that there are likely individual differences in physiological response to traumatic stress. This study goes further to identify the psychological concomitants of these individual differences within an adult population exposed to potentially traumatic events (PTEs), and their proclivity for using different defense mechanisms. Defense use …

Synthesis Of Biologically Important C-Glycosides From Simple C-Glycosyl Alkenes, Ahmad Sabri Altiti

Dissertations, Theses, and Capstone Projects

C-Glycosides are carbohydrate analogues in which the glycosidic oxygen is replaced with a methylene substituent. Because of their stability under acidic hydrolysis or enzymatic cleavage, they are widely used as mimetics of their parent O-glycosides in medicinal chemistry. This thesis describes the development of new synthetic methods for C-glycosides, which center on the use of readily available, simple C-allyl glycosides as precursors. C- glycosides of three structurally distinct and pharmacologically interesting carbohydrates, the immunostimulatory glycolipid C-KRN700, the insulin mimetic glycoinositol β-galactosamine-(1→4)-3-O-methyl-D-chiro-inositiol (INS-2), and α-mannose-(1→6)-D-myo-inositiol, a subunit of the cell wall in Mycobacterium tuberculosis, will be used as test cases for …

A Critical Review Of The Role Of Local Excision In The Treatment Of Early (T1 And T2) Rectal Tumors, Thomas A. Heafner, Sean C. Glasgow

Open Access Publications

The optimal treatment of early (T1 and T2) rectal adenocarcinomas remains controversial. Local excision and radical resection with total mesorectal excision are the two surgical techniques for excising early rectal cancer. Each has their respective benefits, with local excision allowing for decreased operative morbidity and mortality while radical resection provides an oncologically complete treatment through lymphadenectomy. Local excision can be accomplished via transanal endoscopic microsurgery or transanal excision. There is no significant difference in the recurrence rates (21% vs. 33%) or overall survival (80% vs. 66%) between the two local excision modalities; however, transanal endoscopic microsurgery does allow for a …

Double Take: The Law Of Embezzled Lives, Lawrence M. Friedman, Joanna L. Grossman

Hofstra Law Faculty Scholarship

An essay is presented on laws that govern the identity of a person. The case of Notre Dame football player Manti Te'o, who became a victim of an Internet hoax through her girlfriend, Lennay Kekua. It also outlines the laws that deal with double lives and role-playing in law and society and how the government responds to it to protect the people's identity.

Fact Book 2014, Planning, Research, And Policy Analysis

Fact Book (1988-2019)

Fact Book 2014 for Illinois State University

Enrollment Report, Fall 2014, Planning, Research, And Policy Analysis

Enrollment Reports (2004-2019)

Enrollment Report for Fall 2014 for Illinois State University

Sorption Of Cr(Iii) And Cr(Vi) To High And Low Pressure Synthetic Nano-Magnetite (Fe3o4)Particles, Jason Parsons, Jeffrey Hernandez, Christina M. Gonzalez, J. L. Gardea-Torresdey

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

The binding of Cr(III) and Cr(VI) to synthetic nano-magnetie particles synthesized under open vessel conditions and a microwave assisted hydrothermal synthesis techniques was investigated. Batch studies showed that the binding of both the Cr(III) and Cr(VI) bound to the nano-materials in a pH dependent manner. The Cr(III) maximized at binding at pH 4 and 100% binding. Similarly, the Cr(VI) ions showed a maximum binding of 100% at pH 4. The data from the time dependency studies showed for the most part the majority of the binding occurred within the first 5 minutes of contact with the nanomaterial and remained constant …

The Ecology Of Infancy And Early Childhood In Rural Senegal; A Five Year Old Can Boot But Not Foot, An Exploration Of Where Biology Meets Culture, Heather Mills

Independent Study Project (ISP) Collection

This research project explores the life stages of infancy and early childhood in the village of Ndiane in the Thies region of Senegal. I will discuss how biology meets culture to influence children, parenting styles, and expectations of the life stage. How does ecology, the interaction of physical, biological and cultural landscapes, characterize childhood and the intertwined belief systems that influence parenting? The information was gathered using a combination of participant observation and free list interviews.

“I Pray You Enough”: Exploring Rural Early Childhood Development Through The Narratives Of Caregivers., Bethany G. Hart

Independent Study Project (ISP) Collection

Childhood, including the antenatal period, is a time of invaluable physical and mental development – the effects of which last a lifetime. These experiences are shaped by a host of external factors (such as nutrition or mental stimulation) that are heavily affected by socioeconomic status. A study by the United Nations International Childrens Emergency Fund (UNICEF) found that South African children in rural areas are more physically and cognitively delayed than their less-rural peers (2007). Thus, the purpose of this study was to gain insight into the rearing and development of young children (5 years and under) in a rural …

The Sociology Of The Home An Autoethnography That Explores House Building In Rural Sandanezwe, Oliver Hayward

Independent Study Project (ISP) Collection

This project took me to Sandanezwe, KwaZulu-Natal, a rural village outside of Pietermaritzburg, South Africa, where a community member, Mpume Khanyezi, had originally asked me to design and build a new home for her family. I intended to engage in a heuristic inquiry so that I could complete a daily practice of letting go of my own opinions and immersing myself in the community in order to better act as a scribe for the mother and analyze the community objectively. I attempted to gather qualitative data through interviews, active participation, direct observations with village members and building parties. Ultimately, my …

A Crude Awakening: The Relationship Between Petroleum Exploration And Environmental Conservation In Western Uganda, Kristina Ericson

Independent Study Project (ISP) Collection

In this study the researcher aims to explore the emerging oil and natural gas processes in the Republic of Uganda and the potential impacts that such exploration will generate upon Uganda’s biodiversity and local livelihoods. The researcher will approach this topic through extensive research on emerging and current legal frameworks pertaining to Uganda’s natural environment, and through practicum-based research via leading non-profit organizations in Uganda.

During the research process the researcher worked as a Student Research Intern with International Alert. International Alert is an international Non-Governmental Organization (NGO) that works to promote peace building and conflict resolution in over thirty …

Women’S Involvement In Unrwa Family Planning Services: A Study Of Palestinian Refugees In Jordan, Madelyn B. Goodman

Independent Study Project (ISP) Collection

Jordan’s total fertility rate has remained stagnant at 3.5 births per woman since the early 2000s (Malkawi, 2013). Palestinian refugees make up 20% of the population of Jordan, significantly contributing to this fertility rate (Jordan: UNRWA, 2014). The purpose of this study was to investigate the perceived level of voice Palestinian women have in family planning counseling at UNRWA clinics and how this perception influenced the success of the counseling. The research was built on the hypothesis that a low level of patient input and consultation during family planning counseling appointments at UNRWA clinics contributed to the stagnated fertility rate. …

Surgeon Practices And Attitudes Toward The Control Of Surgical-Site Infections In Jordan, Sara Ali Mater

Independent Study Project (ISP) Collection

The purpose of this study was to determine the attitudes and practices of Jordanian surgeons on the control of surgical-site infections, evaluated by the Center of Disease Control’s guidelines toward the prevention of surgical-site infections, in addition to gaining respondents opinions on infection control in Jordan. This study was conducted through the distribution of 75 questionnaires given to surgeons at five hospitals in Jordan. Additional insight on SSI infection control was gained through interviews with two cardiac surgeons and three infection control directors. The results of the survey were compared with the Center for Disease Control’s guide to surgical-site infection …

Mcnair Scholars Research Journal Vii, St. Mary's University

McNair Scholars Research Journal

This is the seventh journal for the McNair Scholars Program at St. Mary's University.

"The Ronald E. McNair Postbaccalaureate Achievement Program is a federally funded TRIO program that was designed to honor Dr. McNair by supporting and encouraging first generation, low-income students from groups traditionally underrepresented in graduate education to pursue and earn doctoral degrees. St. Mary’s University McNair Scholars Program has now received its second award, enabling the program to serve another cohort of deserving undergraduates. St. Mary’s program is unique in that it includes students from Humanities & Social Sciences, the Bill Greehey School of Business and the …

Still Seeking Justice: The Marshall Inquiry Narratives

UBC Law Review

No abstract provided.

Ursinus Magazine, Fall 2014, Wendy Greenberg, Kathryn Campbell, Ellen Labrecque, Jennifer Meininger Wolfe, Terry Winegar, Colin Fong

Ursinus Magazine, 1995–Present

Life and work as a calling • A community reflects • A voice for excellence • Man on a mission • An impact far beyond the gateway • On call at the National Aquarium • To Uganda with love • The gentleman judge • Treating the whole person • Class notes • Weddings • Births • Deaths • In memoriam • Events • Field notes: Fielding theories on baseball, big salaries and opportunistic behavior

Epigenetics And Social Context: Implications For Disparity In Cardiovascular Disease, Karen L. Saban, Herbert L. Matthews, Holli A. Devon, Linda W. Janusek

Nursing: School of Nursing Faculty Publications and Other Works

BACKGROUND:

Although it is well established that African Americans (AA) experience greater social stressors than non-Hispanic Whites (NHW), the extent to which early life adversity and cumulative social stressors such as perceived discrimination, neighborhood violence, subjective social status, and socioeconomic status contribute to disparity in coronary heart disease (CHD) and stroke between AA and NHW are not well understood.

PURPOSE:

The purpose of this paper is to propose a conceptual model based upon McEwen’s Allostatic Load Model suggesting how the relationships among social context, early life adversity, psychological stress, inflammation, adaptation, and epigenetic signature may contribute to the development of …

Fluid-Induced Propulsion Of Rigid Particles In Wormlike Micellar Solutions, David A. Gagnon, Nathan C. Keim, Xiaoning Shen, Paulo E. Arratia

Physics

In the absence of inertia, a reciprocal swimmer achieves no net motion in a viscous Newtonian fluid. Here, using tracking methods and birefringence imaging, we investigate the ability of a reciprocally actuated particle to translate through a complex fluid that possesses a network. A geometrically polar particle, a rod with a bead on one end, is reciprocally rotated using magnetic fields. The particle is immersed in a wormlike micellar (WLM) solution that is known to be susceptible to the formation of shear bands and other localized structures due to shear-induced remodeling of its microstructure. Results show that the nonlinearities present …

Application Of Satellite Data To Model Storm Runoff Into Rosamond Dry Lake, Mridul Oli

LMU Theses and Dissertations

Antelope Valley is situated in Southern California and is bounded by the Tehachapi and the San Gabriel Mountains. It stretches over 2,200 mi2 and encompasses Rosamond Dry Lake and the 1,200 mi2 watershed draining into it. The cities of Lancaster and Palmdale are the two major urban centers that lie in the watershed draining into Rosamond Dry Lake. The lake lies within the vicinity of the Edwards Air Force Base and provides an important site for aviation research and test operations in addition to ecosystem services. Hence, it is necessary to balance the need to remove water from the lake …

The Normal Review, A Literary And Arts Publication, Fall 2014, The Normal Review

The Normal Review

No abstract provided.

Non-Price Competition In “Substitute" Drugs: The Ftc's Blind Spot, Gregory Dolin

All Faculty Scholarship

As the recent case of United States v. Lundbeck illustrates, the Federal Trade Commission’s lack of knowledge in medical and pharmacological sciences affects its evaluation of transactions between medical and pharmaceutical companies that involve transfers of rights to manufacture or sell drugs, causing the agency to object to such transactions without solid basis for doing so. This article argues that in order to properly define a pharmaceutical market, one must not just consider the condition that competing drugs are meant to treat, but also take into account whether there are “off-label” drugs that are used to treat a relevant condition, …

Envision, Fall 2014, Andrews University

Envision

No abstract provided.

The Effects Of Simulated Spermophilus Franklinii Burrowing On Prairie Soil Invertebrate Communities, Nicholas G. Brown

All Student Theses and Dissertations

Burrowing of subterranean mammals can have ecological effects on overlying vegetation, invertebrate communities, and surrounding soil characteristics. Franklin’s ground squirrel (Spermophilus franklinii) is a declining, tunneling mammal species previously found throughout Central Illinois. Preference for natural tallgrass prairie habitat with loose soil marks Illinois as the southern extreme of their range. Through urbanization and agricultural practices this species’ population numbers have declined dramatically in southern and central Illinois. This study looks at the effects simulated Franklin’s ground squirrel burrows have on soil invertebrate composition, abundance, and diversity by comparing effects of the presence/exclusion of burrows, animals, and their …

Amphibian Conservation In Urban Areas, Emma Trewhitt

Department of Environmental Studies: Undergraduate Student Theses

The topic of amphibian decline has become a primary concern partially due to increased urbanization causing habitat loss and fragmentation (Fahrig, 2003). Focusing on this, a project was outlined with the main goal to enhance the conservation and ensure sustainable biodiversity of native amphibians within a substantially urbanized habitat. Currently, there are several storm water retention ponds, and aesthetic ponds around the parking lot and within the Omaha Henry Doorly Zoo. Utilization of these ponds by amphibian species will be examined through frog call surveys and visual occurrences. From the results of these surveys, we are better able to understand …

Nondiscrimination In Insurance: The Next Chapter, Mary L. Heen

Law Faculty Publications

Modern federal civil rights legislation prohibits race and gender discrimination in many important sectors of the American economy, including employment, education, public accommodations, housing, and credit. No comparable comprehensive federal civil rights legislation bans race and gender discrimination in the business of insurance-a business at the core of legal and social organization, culture, and finance. Why not?