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2014

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Say “No” To Nota: Modifying Florida’S Organ Donation Policy Through Government Regulation Of Donor Incentives?, Rachel A. Mattie Jan 2014

Say “No” To Nota: Modifying Florida’S Organ Donation Policy Through Government Regulation Of Donor Incentives?, Rachel A. Mattie

Barry Law Review

No abstract provided.

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Effects Of Keratin Filaments On Erk Signaling During Fas-Induced Death Of Cervical Cancer (Hela) Cells, Amanda Berger Jan 2014

Effects Of Keratin Filaments On Erk Signaling During Fas-Induced Death Of Cervical Cancer (Hela) Cells, Amanda Berger

Honors Theses and Capstones

Survival of cancer cells is influenced by a variety of factors, including physical elements such as keratin filaments. We know HeLa cells containing or lacking keratin 8/18 intermediate filaments (K+ and K- cells, respectively) are more sensitive to the death-inducing effects of Fas agonist compared to the cytokines tumor necrosis factor alpha (TNF-α) or TNF-related apoptosis-inducing ligand. Additionally, K- cells are more sensitive to Fas-induced death than K+ as shown by previous studies using mitochondrial activity and caspase activation assays. In the current study we tested the hypothesis that keratin filaments associate with the mitogen activated protein kinase (MAPK) cascade …

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Effects Of Sodium Hydroxide Pretreatment On Structural Components Of Biomass, Alicia A. Modenbach, Sue E. Nokes Jan 2014

Effects Of Sodium Hydroxide Pretreatment On Structural Components Of Biomass, Alicia A. Modenbach, Sue E. Nokes

Biosystems and Agricultural Engineering Faculty Publications

Pretreatment is a unit operation in the conversion of biomass to valuable products that utilizes various combinations of conditions, including chemicals, heat, pressure, and time, to reduce the recalcitrance of lignocellulose. Many such pretreatments have been developed over the years, as the operating conditions can be adapted so that lignocellulose is modified in ways unique to each pretreatment. By tailoring pretreatment conditions to achieve these modifications, the types of final products produced can be controlled. The purpose of this review is to provide a consolidated source of information for sodium hydroxide effects on lignocellulose. The structural characteristics of lignocellulose and …

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"Other Than Dead": Queering Vampires In Buffy The Vampire Slayer, Interview With The Vampire, And The Gilda Stories, Megan E. Gianniny Jan 2014

"Other Than Dead": Queering Vampires In Buffy The Vampire Slayer, Interview With The Vampire, And The Gilda Stories, Megan E. Gianniny

Scripps Senior Theses

This thesis examines three diverse vampire narratives from around the 1990s, arguing that the liminal figure of the vampire, forever in between life and death, is also then well-positioned to queer norms around gender, sexuality, and relationships. This queering, however, manifests differently in each narrative. My analysis looks at each of these three narratives in turn, while also considering how each text’s placement as mainstream or not mainstream affected the manifestation of the vampires’ queering.

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Cultural Factors In Mental Health Referral Among Asian Americans, Ishani Deo Jan 2014

Cultural Factors In Mental Health Referral Among Asian Americans, Ishani Deo

Scripps Senior Theses

Epidemiological studies have shown that disparities in mental health service utilization still exist among ethnic minority groups in the United States. This study looks specifically at the lay referral system and what factors influence the likelihood of an individual referring a friend to mental health services. Since college student populations have fewer barriers than most to seeking treatment, 60 Asian American and 49 White American college students were sampled for the purposes of this study. They evaluated one of four vignettes in which cultural competency of the potential therapist and type of symptoms being presented were manipulated. Though there was …

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Discourses Of Menstruation: Public And Private Formations Of Female Identity, Emily G. Matteson Jan 2014

Discourses Of Menstruation: Public And Private Formations Of Female Identity, Emily G. Matteson

Scripps Senior Theses

Menstruation is a biological process, but it is also laden with cultrual meanings that produce society's understandings of both the body and "womanhood." The experiences of those who menstruate both reveal and inform the ways that culture mediates the relationships between biology, the body, sex, and gender. This study examines the ways that students at Scripps College, a women's college in Claremont, CA, understand and experience menstruation as part of living in an environment where the majority of students identify as female. Through ethnographic interviews, I demonstrate the ways that students use menstruation to re-envision distinctions between public and private …

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Magical Me: Self-Insertion Fanfiction As Literary Critique, Melody Strmel Jan 2014

Magical Me: Self-Insertion Fanfiction As Literary Critique, Melody Strmel

Scripps Senior Theses

This thesis examines the traditions of textual interaction that impact the forms of reading engaged in with fanfiction. This thesis continues by exploring how self-insertion fanfiction functions as a medium through which authors express their reading of the text primary through the emotional impact of the text through wish fulfillment, and the interaction of their cultural moment and the text. Furthermore, it argues that self-insertion fanfiction is a mode of literary critique in which the author acknowledges the effect of a mediated world on their perception of self and reality. Through this recognition of a constructed self, the author rejects …

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Statutory Royalty Damages Under The Uniform Trade Secrets Act And The Federal Patent Code, Richard F. Dole Jr. Jan 2014

Statutory Royalty Damages Under The Uniform Trade Secrets Act And The Federal Patent Code, Richard F. Dole Jr.

Vanderbilt Journal of Entertainment & Technology Law

Optional statutory royalty damages are provided for by both the version of the Uniform Trade Secrets Act that has been enacted by most of the forty seven adopting states and the federal patent code remedies for infringement of utility patents. Notwithstanding periodic recommendations that the Uniform Act follow the patent code concept of statutory royalty damages, this article takes the position that differences between the Uniform Act and the Patent Code regarding monetary remedies make it reasonable for the Uniform Act statutory royalty provisions to be construed more objectively than their federal counterpart. This will preclude statutory royalty damages acquiring …

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Benthic And Pelagic Pathways Of Methylmercury Bioaccumulation In Estuarine Food Webs Of The Northeast United States, Celia Y. Chen, Mark E. Borsuk, Deenie M. Bugge, Terill Hollweg Jan 2014

Benthic And Pelagic Pathways Of Methylmercury Bioaccumulation In Estuarine Food Webs Of The Northeast United States, Celia Y. Chen, Mark E. Borsuk, Deenie M. Bugge, Terill Hollweg

Dartmouth Scholarship

Methylmercury (MeHg) is a contaminant of global concern that bioaccumulates and bioamagnifies in marine food webs. Lower trophic level fauna are important conduits of MeHg from sediment and water to estuarine and coastal fish harvested for human consumption. However, the sources and pathways of MeHg to these coastal fisheries are poorly known particularly the potential for transfer of MeHg from the sediment to biotic compartments. Across a broad gradient of human land impacts, we analyzed MeHg concentrations in food webs at ten estuarine sites in the Northeast US (from the Hackensack Meadowlands, NJ to the Gulf of Maine). MeHg concentrations …

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Synthetic Triterpenoids Can Protect Against Toxicity Without Reducing The Efficacy Of Treatment With Carboplatin And Paclitaxel In Experimental Lung Cancer, Karen T. Liby Jan 2014

Synthetic Triterpenoids Can Protect Against Toxicity Without Reducing The Efficacy Of Treatment With Carboplatin And Paclitaxel In Experimental Lung Cancer, Karen T. Liby

Dartmouth Scholarship

Synthetic oleanane triterpenoids are multifunctional drugs being developed for the prevention and treatment of a variety of chronic diseases driven by inflammation and oxidative stress. Low nanomolar concentrations of triterpenoids inhibit the induction of inflammatory cytokines, and these drugs are potent activators of the Nrf2 cytoprotective pathway. In contrast, low micromolar concentrations of triterpenoids increased the production of ROS and induced apoptosis in a dose-dependent manner in malignant MCF10 CA1a breast cancer cells. Because cancer cells respond differently to ROS than normal cells, it should be possible to exploit these differences therapeutically. In an experimental model of lung cancer, the …

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Commentary On: "Facilitating Transparency In Spinal Cord Injury Studies Using Data Standards And Ontologies", Diane M. Snow Jan 2014

Commentary On: "Facilitating Transparency In Spinal Cord Injury Studies Using Data Standards And Ontologies", Diane M. Snow

Spinal Cord and Brain Injury Research Center Faculty Publications

No abstract provided.

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Are Major Repeater Patients Addicted To Suicidal Behavior?, Hilario Blasco-Fontecilla, Paula Artieda-Urrutia, Nuria Berenguer-Elias, Juan Manuel Garcia-Vega, Monica Fernandez-Rodriguez, Cesar Rodriguez-Lomas, Isabel Gonzalez-Villalobos, Luis Iruela-Cuadrado, Jose De Leon Jan 2014

Are Major Repeater Patients Addicted To Suicidal Behavior?, Hilario Blasco-Fontecilla, Paula Artieda-Urrutia, Nuria Berenguer-Elias, Juan Manuel Garcia-Vega, Monica Fernandez-Rodriguez, Cesar Rodriguez-Lomas, Isabel Gonzalez-Villalobos, Luis Iruela-Cuadrado, Jose De Leon

Psychiatry Faculty Publications

The literature provides support for the hypothesis that some major repeaters (individuals with >=5 lifetime suicide attempts) are addicted to suicidal behavior (SB). This study explores whether major repeaters are addicted to SB or not using 7 criteria: tolerance (Criterion 1), withdrawal (Criterion 2), loss of control (Criterion 3), problems in quitting/cutting down (Criterion 4), much time spent using (Criterion 5), substantial reduction in activities (Criterion 6), and adverse physiological/physical consequences (Criterion 7). Total dependence on SB was indicated by the presence of 3 or more of the 7 criteria in the last 12 months. This cross-sectional study at Puerta …

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Scientific Overview: 2013 Bbc Plenary Symposium On Tobacco Addiction, Mariella De Biasi, I. Mclaughlin, E. E. Perez, Peter A. Crooks, Linda P. Dwoskin, Michael T. Bardo, P. R. Pentel, Dorothy Hatsukami Jan 2014

Scientific Overview: 2013 Bbc Plenary Symposium On Tobacco Addiction, Mariella De Biasi, I. Mclaughlin, E. E. Perez, Peter A. Crooks, Linda P. Dwoskin, Michael T. Bardo, P. R. Pentel, Dorothy Hatsukami

Psychology Faculty Publications

Nicotine dependence plays a critical role in addiction to tobacco products, and thus contributes to a variety of devastating tobacco-related diseases (SGR 2014). Annual costs associated with smoking in the US are estimated to be between $289 and $333 billion. Effective interventions for nicotine dependence, especially in smokers, are a critical barrier to the eradication of tobacco-related diseases. This overview highlights research presented at the Plenary Symposium of Behavior, Biology and Chemistry: Translational Research in Addiction Conference (BBC), hosted by the UT Health Science Center San Antonio, on March 9–10, 2013. The Plenary Symposium focused on tobacco addiction, and covered …

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Enhancing The Care Navigation Model: Potential Roles For Health Sciences Librarians, Jeffrey T. Huber, Robert M. Shapiro Ii, Heather J. Burke, Aaron Palmer Jan 2014

Enhancing The Care Navigation Model: Potential Roles For Health Sciences Librarians, Jeffrey T. Huber, Robert M. Shapiro Ii, Heather J. Burke, Aaron Palmer

Information Science Faculty Publications

This study analyzed the overlap between roles and activities that health care navigators perform and competencies identified by the Medical Library Association's (MLA's) educational policy statement. Roles and activities that health care navigators perform were gleaned from published literature. Once common roles and activities that health care navigators perform were identified, MLA competencies were mapped against those roles and activities to identify areas of overlap. The greatest extent of correspondence occurred in patient empowerment and support. Further research is warranted to determine the extent to which health sciences librarians might assume responsibility for roles and activities that health care navigators …

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Firesetting, Sexual Abuse And Long-Term Consequences, Lesley Davidson, Hatim A. Omar Jan 2014

Firesetting, Sexual Abuse And Long-Term Consequences, Lesley Davidson, Hatim A. Omar

Pediatrics Faculty Publications

In this chapter we summarize the limited studies on post-pubertal consequences of female childhood sexual abuse that includes both psychological distress and physiological stress. The characteristics of sexual abuse are discussed and determined to play a major role in the degree of trauma experienced and in the later effects. The concept of hormones and how disruptions in various endocrine systems can affect the development of these females are examined, especially during the pubertal period. Outcomes of interest included competence, in terms of cognitive, social, self-esteem, and locus of control, and psychopathology including depression, anxiety, dissociation, and hypersexuality. Direct physical results …

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Self-Reported Juvenile Firesetting, Carrie Howell Bowling, Hatim A. Omar Jan 2014

Self-Reported Juvenile Firesetting, Carrie Howell Bowling, Hatim A. Omar

Pediatrics Faculty Publications

In this chapter we address gaps in existing research by examining the relationship between academic performance and attention problems with juvenile firesetting. Two datasets from the Achenbach System for Empirically Based Assessment (ASEBA) were used. The Factor Analysis Dataset (N = 975) was utilized and results indicated that adolescents who report lower academic performance are more likely to set fires. Additionally, adolescents who report a poor attitude toward school are even more likely to set fires. Logistic regressions were run to determine if attention problems predicted firesetting and the findings indicated that attention problems are predictive of self-reported firesetting. The …

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Adolescent Bereavement, Leslie Robin, Hatim A. Omar Jan 2014

Adolescent Bereavement, Leslie Robin, Hatim A. Omar

Pediatrics Faculty Publications

Depending on cognitive and emotional development, an adolescent may grieve very differently than a child or an adult. While mature enough to understand death's irreversibility, adolescents may not fully comprehend the enduring consequences of a loved one's death. As the desire to separate from their families and forge new intimate relationships with peers assumes increasing priority, adolescents can seem egocentric in their reaction to death, a response which often frustrates and perplexes adults. Because volatile behavior is characteristic of adolescence, health providers struggle to differentiate between normal and complicated bereavement. Here we review the commonly-accepted characteristics of normal and complicated …

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Disability And Women's Health, Stephanie Stockburger, Hatim A. Omar Jan 2014

Disability And Women's Health, Stephanie Stockburger, Hatim A. Omar

Pediatrics Faculty Publications

Children, adolescents, and women with disabilities experience the same sexual development, pubertal changes, concerns, and desire to reproduce as their typically developing counterparts. However, society has tended to stigmatize women with disabilities as "asexual" and ignore this aspect of their health care. These women are less likely to receive gynecological exams, contraception, and evaluation of sexual dysfunction. Unfortunately, having a disability places women at risk for sexual exploitation and abuse as well as sexually transmitted infections. Therefore, reproductive health care for these women is imperative. A number of barriers to receiving reproductive care exist. However, with proper education and knowledge …

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Family Environmental Health And Teen Outcomes, Lesley Davidson, Alissa Briggs, Hatim A. Omar Jan 2014

Family Environmental Health And Teen Outcomes, Lesley Davidson, Alissa Briggs, Hatim A. Omar

Pediatrics Faculty Publications

Understanding the impact of family dynamics on health has become an environmental health priority in the field of adolescent medicine. Family dynamics are much more complex than they were 60 years ago and so are behavioral outcomes. This transformation in the American family has led towards a large array of adolescent living situations. Rural Kentucky is a prime example of an area with a high rate of nontraditional family composition. Poor family dynamics may be associated with increased rates of high risk behaviors among teenagers. Among these behaviors are drug use, sexual activity, and depression. In this study, we evaluated …

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Academic Predictors And Characteristics Of Self-Reported Juvenile Firesetting, Carrie Howell Bowling, Hatim A. Omar Jan 2014

Academic Predictors And Characteristics Of Self-Reported Juvenile Firesetting, Carrie Howell Bowling, Hatim A. Omar

Pediatrics Faculty Publications

The main purpose of this study was to address gaps in existing research by examining the relationship between academic performance and attention problems with juvenile firesetting. Two datasets from the Achenbach System for Empirically Based Assessment (ASEBA) were used. The Factor Analysis Dataset (N = 975) was utilized and results indicated that adolescents who report lower academic performance are more likely to set fires. Additionally, adolescents who report a poor attitude toward school are even more likely to set fires. Logistic regressions were run to determine if attention problems predicted firesetting and the findings indicated that attention problems are predictive …

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An Investigation And Evaluation Of The Proposed Harbour Development In Bantry Bay, Cork, Shane O'Flynn Jan 2014

An Investigation And Evaluation Of The Proposed Harbour Development In Bantry Bay, Cork, Shane O'Flynn

Theses

RPS Group was appointed by Bantry Bay Harbour Commissioners to develop a master plan for a waterfront development in Bantry Bay Inner Harbour. It has been proposed that the inner harbour be dredged to a sufficient water depth to allow the entrance of marine craft. The purpose of the thesis is to evaluate and discuss the decisions regarding the environmental impacts that a harbour development would have on Bantry Bay. This research investigates the feasibility of alternative dredge treatment processes used in the Bantry Bay Inner Harbour Development. This research investigates the possibility of reusing the dredge material on site, …

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Young People’S Mental Health Awareness (Including An Evaluation Of A Mental Health Promoting Pilot Project Developed In Connaught), Pamela Kent Jan 2014

Young People’S Mental Health Awareness (Including An Evaluation Of A Mental Health Promoting Pilot Project Developed In Connaught), Pamela Kent

Theses

Adolescence is a particularly vulnerable life stage during which mental health challenges can occur and “in order to create a positive state of mental health and well-being it is imperative for young people to be able to recognise which aspects of life have a positive and damaging effect on their mental health” (HSE, 2007: 14). Irish research states that “Positive mental health enables young people to live fulfilling lives and promoting the mental health and wellbeing of our young people is a shared responsibility and is everybody’s business” (Department of Education and Skills & Health Service Executive & Department of …

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Do Irish Consumers Understand Financial Risk In Savings And Investment Products In The Irish Financial Services Market?, Alan N. Burrows Jan 2014

Do Irish Consumers Understand Financial Risk In Savings And Investment Products In The Irish Financial Services Market?, Alan N. Burrows

Theses

This thesis focuses on Irish adult consumers and examines whether they understand the financial risk pertaining to the savings and investment products that they purchase in the Irish financial services market. This study is important because there is no up to date data currently available on this topic, specifically and solely related to Ireland and to Irish consumers. The findings of this study are significant because, if consumers lack an understanding of financial risk, it can potentially lead to mistakes in financial decisions which may lead to negative financial repercussions for consumers throughout their life and into retirement. In this …

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Technological Literacy Courses In Pre-Service Teacher Education, Roger Skophammer, Philip A. Reed Jan 2014

Technological Literacy Courses In Pre-Service Teacher Education, Roger Skophammer, Philip A. Reed

STEMPS Faculty Publications

The goal of this study was to determine to what extent technological literacy courses were required in K-12 teacher education. A documents review of the appropriate course catalogs for initial teacher preparation was conducted. The documents review identified general education requirements and options for technological literacy courses, as well as requirements and options for these courses for English, social studies, mathematics, and science education majors. For this study, technological literacy was defined as "the ability to use, manage, assess, and understand technology" (ITEA, 2000/2002/2007, p. 9). This definition of literacy is broader than technology literacy associated with computer use and …

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The Value Of Words: Narrative As Evidence In Policymaking, Dmitry Epstein, Josiah Heidt, Cynthia R. Farina Jan 2014

The Value Of Words: Narrative As Evidence In Policymaking, Dmitry Epstein, Josiah Heidt, Cynthia R. Farina

Cornell Law Faculty Publications

Policymakers today rely primarily on statistical, financial, and other forms of technical data as their basis for decision-making. Yet, there is a potentially underestimated value in substantive reflections of the members of the public who will be affected by a particular piece of regulation. We discuss the value of narratives as input in the policy making process, based on our experience with Regulation Room–a product of an interdisciplinary initiative using innovative web technologies in real-time online experimentation. We describe professional policymakers and professional commenters as a community of practice that has limited shared repertoire with the lay members of the …

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The Rate And Process Of Mangrove Forest Expansion On Above- And Belowground Carbon Relations In Coastal Louisiana, Hai Thanh Pham Jan 2014

The Rate And Process Of Mangrove Forest Expansion On Above- And Belowground Carbon Relations In Coastal Louisiana, Hai Thanh Pham

Dissertations

Global climate change is a major environmental threat to natural and cultural resources in low-lying coastal zones and deltas worldwide. It is expected to have a significant effect on the development of coastal wetlands by changing species range expansion. In fact, recent studies have shown that there has been an increasing mangrove encroachment poleward in the Southern and Northern Hemispheres into temperate saltmarsh zones due to the lack of freeze events. This phenomenon could have a critical impact on the structure and function of tidal wetlands at critical latitudes, especially in carbon sequestration, since mangroves are thought to sequester more …

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Differentiation Of U-937 Monocytes To Macrophage-Like Cells Polarized Into M1 Or M2 Phenotypes According To Their Specific Environment: A Study Of Morphology, Cell Viability, And Cd Markers Of An In Vitro Model Of Human Macrophages, Fatma Husien S. Abdulhadi Jan 2014

Differentiation Of U-937 Monocytes To Macrophage-Like Cells Polarized Into M1 Or M2 Phenotypes According To Their Specific Environment: A Study Of Morphology, Cell Viability, And Cd Markers Of An In Vitro Model Of Human Macrophages, Fatma Husien S. Abdulhadi

Browse all Theses and Dissertations

In this study, the human leukemic monocyte lymphoma cell line U-937 was used as an in vitro model for monitoring monocyte/macrophage differentiation. Phorbol 12- myristate (13) (PMA) was used to activate U-937 cells into macrophage-like cells (M0). After 24 hours of PMA treatment, non- adherent U-937 cells became tightly adherent to the culture plates forming M0 cells. M0 cells were then polarized into the M1 macrophage phenotype by treatment with LPS and IFN-γ for another 24 hours. Each of the cytokines IL-4, IL-13, or IL-10 was applied separately to three M0 cultures for 24 hours to induce the M2 macrophage …

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Challenge Accepted: Self-Enhancement Through The Pursuit Of Difficulty, Julie Anne Steinke Jan 2014

Challenge Accepted: Self-Enhancement Through The Pursuit Of Difficulty, Julie Anne Steinke

Browse all Theses and Dissertations

Individual resilience is popular topic whereby researchers attempt to identify characteristics of individuals who react positively to stress. However, such research uses a reactionary approach, attempting to characterize successful individuals after they experience adversity and does not explain why some individuals proactively seek out challenging circumstances. Pursuing challenge is a new construct that explains why individuals proactively increase stress as a strategic mechanism for developmental purposes. I developed and validated a measurement tool for pursuing challenge in multiple studies. Additionally, I explored relationships between pursuing challenge and similar constructs (e.g., grit, proactive personality, and self-efficacy), as well as the extent …

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Direct Writing Of Polymeric Coatings For Corrosion Control And Tunable Release Of Bioactive Materials, Eben Adarkwa Jan 2014

Direct Writing Of Polymeric Coatings For Corrosion Control And Tunable Release Of Bioactive Materials, Eben Adarkwa

Dissertations

The interface between a medical device and its surrounding tissue can be critical to biocompatibility, performance and therapeutic effectiveness. Careful choice and application of materials at this interface is therefore a key to the success of any medical device. This research employed a novel direct-write inkjet printing technique for polymeric surface modification of bioresorbable AZ31 Mg alloy towards corrosion control and tunable release of bioactive agents. In the first phase of this research, the direct-write inkjet printing technique was successfully used to fabricate thin films of different blends of poly (ester-urethane) urea embedded with taxol coatings on mechanically polished AZ31 …

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Effects Of Nanosilver And Silver Nitrate Exposure On Fathead Minnows (Pimephales Promelas) And Zebrafish (Danio Rerio), Adam D. Hawkins Jan 2014

Effects Of Nanosilver And Silver Nitrate Exposure On Fathead Minnows (Pimephales Promelas) And Zebrafish (Danio Rerio), Adam D. Hawkins

Electronic Theses and Dissertations

Silver nanoparticles (AgNPs) due to their unique antimicrobial properties are among the most widely utilized nanoparticle. Because of the nature of the products that utilize AgNPs, environmental release of AgNPs is inevitable. At greatest risk is the aquatic ecosystem due to known toxicity of the Ag + ion to aquatic organisms. Our goal was to use two fish models, fathead minnows (Pimephales promelas; FHMs) and zebrafish ( Danio rerio; ZFs), to study the effects of AgNPs on gill histopathology, Na+/K+-ATPase immunoreactivity, mucus production, bioaccumulation, particle uptake characterization, gill gene expression, and lethality in varying water parameters in comparison to the …

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