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Articles 16021 - 16050 of 25966
Full-Text Articles in Entire DC Network
Cwu Curriculum Committee Minutes - 01/09/14, Janet Shields
Cwu Curriculum Committee Minutes - 01/09/14, Janet Shields
All Faculty Committee Minutes
These are the official Central Washington University Curriculum Committee minutes for the 01/09/14 meeting.
Lanthorn, Vol. 48, No. 32, January 9, 2014, Grand Valley State University
Lanthorn, Vol. 48, No. 32, January 9, 2014, Grand Valley State University
Volume 48, July 1, 2013 - June 2, 2014
Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.
Corrected Financial Data For Direction Package Advisory Board, Direction Package Advisory Board
Corrected Financial Data For Direction Package Advisory Board, Direction Package Advisory Board
Direction Package
No abstract provided.
Curriculum Subcommittee Agenda, January 9, 2014, Utah State University
Curriculum Subcommittee Agenda, January 9, 2014, Utah State University
Educational Policies Committee
School of Veterinary Medicine
- New Course
- Credit Hour Change
School of Applied Sciences, Technology and Education
- New Course
Department of Agricultural Systems Technology and Education
- New Course
- Prerequisite Change
- Title Change, Prerequisite Change, Course Description Change
- Title Change, Course Description Change
Department of Art and Design
- Dual List Change
Department of Economic and Finance
- Title Change
Department of Management
- New Course
- Title Change
- Title Change, Prerequisite Change
Department of Management Information Systems
- Title Change, Course Description Change
- Prerequisite Change
- Prerequisite Change, Course Description Change
Department of Psychology
- New Course
College of Engineering
- University Studies Request
Department of Languages, Philosophy and …
Educational Policies Committee Agenda, January 9, 2014, Utah State University
Educational Policies Committee Agenda, January 9, 2014, Utah State University
Educational Policies Committee
- Subcommittee Reports
- Curriculum Subcommittee
- Course Approvals
- Academic Standards Subcommittee
- General Education Subcommittee
Educational Policies Committee Minutes, January 9, 2014, Utah State University
Educational Policies Committee Minutes, January 9, 2014, Utah State University
Educational Policies Committee
- Approval of the minutes from Dec 5 2013
- Subcommittee Reports
- Curriculum Subcommittee
- Academic Standards Subcommittee
- General Education Subcommittee
Prognosis Of Differentiated Thyroid Cancer In Relation To Serum Thyrotropin And Thyroglobulin Antibody Status At Time Of Diagnosis, Donald S. A. Mcleod, David S. Cooper, Paul W. Ladenson, Kenneth B. Ain, James D. Brierley, Henry G. Fein, Bryan R. Haugen, Jacqueline Jonklaas, James Magner, Douglas S. Ross, Monica C. Skarulis, David L. Steward, Harry R. Maxon, Steven I. Sherman
Prognosis Of Differentiated Thyroid Cancer In Relation To Serum Thyrotropin And Thyroglobulin Antibody Status At Time Of Diagnosis, Donald S. A. Mcleod, David S. Cooper, Paul W. Ladenson, Kenneth B. Ain, James D. Brierley, Henry G. Fein, Bryan R. Haugen, Jacqueline Jonklaas, James Magner, Douglas S. Ross, Monica C. Skarulis, David L. Steward, Harry R. Maxon, Steven I. Sherman
Internal Medicine Faculty Publications
BACKGROUND: Serum thyrotropin (TSH) concentration and thyroid autoimmunity may be of prognostic importance in differentiated thyroid cancer (DTC). Preoperative serum TSH level has been associated with higher DTC stage in cross-sectional studies; data are contradictory on the significance of thyroid autoimmunity at the time of diagnosis.
OBJECTIVE: We sought to assess whether preoperative serum TSH and perioperative antithyroglobulin antibodies (TgAb) were associated with thyroid cancer stage and outcome in DTC patients followed by the National Thyroid Cancer Treatment Cooperative Study, a large multicenter thyroid cancer registry.
METHODS: Patients registered after 1996 with available preoperative serum TSH (n=617; the TSH cohort) …
Targeted Cytotoxic Therapy Kills Persisting Hiv Infected Cells During Art, Paul W. Denton, Julie M. Long, Stephen W. Wietgrefe, Craig Sykes, Rae Ann Spagnuolo, Olivia D. Snyder, Katherine Perkey, Nancie M. Archin, Shailesh K. Choudhary, Kuo Yang, Michael G. Hudgens, Ira Pastan, Ashley T. Haase, Angela D. Kashuba, Edward A. Berger, David M. Margolis, J. Victor Garcia
Targeted Cytotoxic Therapy Kills Persisting Hiv Infected Cells During Art, Paul W. Denton, Julie M. Long, Stephen W. Wietgrefe, Craig Sykes, Rae Ann Spagnuolo, Olivia D. Snyder, Katherine Perkey, Nancie M. Archin, Shailesh K. Choudhary, Kuo Yang, Michael G. Hudgens, Ira Pastan, Ashley T. Haase, Angela D. Kashuba, Edward A. Berger, David M. Margolis, J. Victor Garcia
Biology Faculty Publications
Antiretroviral therapy (ART) can reduce HIV levels in plasma to undetectable levels, but rather little is known about the effects of ART outside of the peripheral blood regarding persistent virus production in tissue reservoirs. Understanding the dynamics of ART-induced reductions in viral RNA (vRNA) levels throughout the body is important for the development of strategies to eradicate infectious HIV from patients. Essential to a successful eradication therapy is a component capable of killing persisting HIV infected cells during ART. Therefore, we determined the in vivo efficacy of a targeted cytotoxic therapy to kill infected cells that persist despite long-term ART. …
Revisting The Jordan, Minnesota Cases, Ross E. Cheit, Andrea Matthews
Revisting The Jordan, Minnesota Cases, Ross E. Cheit, Andrea Matthews
Roger Williams University Law Review
No abstract provided.
It's Not A Fad: Incorporating Mobile Devices Into The Classroom, Makiba Foster, Jaleh Fazelian, Ron Cytron
It's Not A Fad: Incorporating Mobile Devices Into The Classroom, Makiba Foster, Jaleh Fazelian, Ron Cytron
WashU Libraries Presentations
According to a 2013 survey, about 40% of college students have used tablets for coursework and two-thirds have used a smartphone. Students also report that they would like to use their mobile devices more often in their courses. This session will provide the opportunity to learn about strategies for incorporating the use of mobile devices in the classroom, including WU-texter, an application developed and implemented by Ron in a computer science course.
Changing Microspatial Patterns Of Sulfate-Reducing Microorganisms (Srm) During Cycling Of Marine Stromatolite Mats, Alexandru I. Petrisor, Sandra Szyjka, Tomohiro Kawaguchi, Pieter T. Visscher, Robert Sean Norman, Alan W. Decho
Changing Microspatial Patterns Of Sulfate-Reducing Microorganisms (Srm) During Cycling Of Marine Stromatolite Mats, Alexandru I. Petrisor, Sandra Szyjka, Tomohiro Kawaguchi, Pieter T. Visscher, Robert Sean Norman, Alan W. Decho
Faculty Publications
Microspatial arrangements of sulfate-reducing microorganisms (SRM) in surface microbial mats (~1.5 mm) forming open marine stromatolites were investigated. Previous research revealed three different mat types associated with these stromatolites, each with a unique petrographic signature. Here we focused on comparing “non-lithifying” (Type-1) and “lithifying” (Type-2) mats. Our results revealed three major trends: (1) Molecular typing using the dsrA probe revealed a shift in the SRM community composition between Type-1 and Type-2 mats. Fluorescence in-situ hybridization (FISH) coupled to confocal scanning-laser microscopy (CSLM)-based image analyses, and 35SO42−-silver foil patterns showed that SRM were present in surfaces of …
"I Don't Know If That Was The Right Thing To Do": Cross-Disciplinary/Cross-Institutional Faculty Respond To L2 Writing, Lindsey Ives, Elizabeth Leahy, Anni Leming, Tom Pierce, Michael Schwartz
"I Don't Know If That Was The Right Thing To Do": Cross-Disciplinary/Cross-Institutional Faculty Respond To L2 Writing, Lindsey Ives, Elizabeth Leahy, Anni Leming, Tom Pierce, Michael Schwartz
Publications
This chapter investigates faculty expectations for student writing, specifically L2 writers of English, across disciplines at a flagship university and an urban community college in the southwest. Drawing from a faculty survey and follow-up interviews with faculty from various disciplines, the authors argue that study participants tend to hold multilingual writers to a monolingual standard, but that they are conflicted and/or ambivalent about this practice. The survey and interview data show, first, that markers of nonnative speaker status or any features that depart from Standard American Academic English often discourage and even preclude engagement with higher order concerns like ideas …
Trip/Nopo E3 Ubiquitin Ligase Promotes Ubiquitylation Of Dna Polymerase Η, Heather A. Wallace, Julie A. Merkle, Michael C. Yu, Taloa G. Berg, Ethan Lee, Giovanni Bosco, Laura A. Lee
Trip/Nopo E3 Ubiquitin Ligase Promotes Ubiquitylation Of Dna Polymerase Η, Heather A. Wallace, Julie A. Merkle, Michael C. Yu, Taloa G. Berg, Ethan Lee, Giovanni Bosco, Laura A. Lee
Dartmouth Scholarship
We previously identified a Drosophila maternal effect-lethal mutant named ‘no poles’ (nopo). Embryos from nopo females undergo mitotic arrest with barrel-shaped, acentrosomal spindles during the rapid cycles of syncytial embryogenesis because of activation of a Chk2-mediated DNA checkpoint. NOPO is the Drosophila homolog of human TNF receptor associated factor (TRAF)-interacting protein (TRIP), which has been implicated in TNF signaling. NOPO and TRIP contain RING domains closely resembling those of known E3 ubiquitin ligases. We herein sought to elucidate the mechanism by which TRIP/NOPO promotes genomic stability by performing a yeast two-hybrid screen to identify potential substrates/interactors. We identified members of …
Intellectual Property, The Free Movement Of Goods And Trade Restraint In The European Union, Jarrod Tudor
Intellectual Property, The Free Movement Of Goods And Trade Restraint In The European Union, Jarrod Tudor
The Journal of Business, Entrepreneurship & the Law
The European Union (“EU”) is the most significant trade partner of the United States. Trading in goods protected by intellectual property rights remains a challenge for American business entities as they are forced to sift through a myriad of law consisting of the federal intellectual property law of the EU and the intellectual property law of the member states. The European Court of Justice (“ECJ” or “the Court”) has been faced with dozens of complex cases arising out of conflicts between the national law of the member states and the Articles of the Treaty on the Functioning of the European …
Quantification Of Transhumeral Prosthetic Socket Residual Limb Interface Movement Using Motion Capture And A Slip Detection Sensor, Matthew Wernke
Quantification Of Transhumeral Prosthetic Socket Residual Limb Interface Movement Using Motion Capture And A Slip Detection Sensor, Matthew Wernke
USF Tampa Graduate Theses and Dissertations
Current literature focusing on the prosthetic socket is limited by measurement techniques and modeling assumptions, leading to a limited understanding of the forces and motions occurring between the residual limb and prosthesis and how they can be used to influence socket design and fitting. Prosthetic socket fitting and prescription would benefit from an elegant method for comparing socket designs. This dissertation focuses on the development and implementation of a 3D motion capture model and a Slip Detection Sensor to quantify rotations and translations at the prosthetic socket-residual limb interface. The 3D motion capture model defines the residual limb bone position …
Warming, Soil Moisture, And Loss Of Snow Increase Bromus Tectorum’S Population Growth Rate, Aldo Compagnoni, Peter B. Adler
Warming, Soil Moisture, And Loss Of Snow Increase Bromus Tectorum’S Population Growth Rate, Aldo Compagnoni, Peter B. Adler
Green Canyon Environmental Research Area, Logan Utah
Climate change threatens to exacerbate the impacts of invasive species. In temperate ecosystems, direct effects of warming may be compounded by dramatic reductions in winter snow cover. Cheatgrass (Bromus tectorum) is arguably the most destructive biological invader in basins of the North American Intermountain West, and warming could increase its performance through direct effects on demographic rates or through indirect effects mediated by loss of snow. We conducted a two-year experimental manipulation of temperature and snow pack to test whether 1) warming increases cheatgrass population growth rate and 2) reduced snow cover contributes to cheatgrass’ positive response to …
The Covert World Of Fish Biofluorescence: A Phylogenetically Widespread And Phenotypically Variable Phenomenon, John S. Sparks, Robert C. Schelly, W. Leo Smith, Matthew P. Davis, Dan Tchernov, Vincent A. Pieribone, David F. Gruber
The Covert World Of Fish Biofluorescence: A Phylogenetically Widespread And Phenotypically Variable Phenomenon, John S. Sparks, Robert C. Schelly, W. Leo Smith, Matthew P. Davis, Dan Tchernov, Vincent A. Pieribone, David F. Gruber
Publications and Research
The discovery of fluorescent proteins has revolutionized experimental biology. Whereas the majority of fluorescent proteins have been identified from cnidarians, recently several fluorescent proteins have been isolated across the animal tree of life. Here we show that biofluorescence is not only phylogenetically widespread, but is also phenotypically variable across both cartilaginous and bony fishes, highlighting its evolutionary history and the possibility for discovery of numerous novel fluorescent proteins. Fish biofluorescence is especially common and morphologically variable in cryptically patterned coral-reef lineages. We identified 16 orders, 50 families, 105 genera, and more than 180 species of biofluorescent fishes. We have also …
Post Disturbance Coral Populations: Patterns In Live Cover And Colony Size Classes From Transect Studies In Two Oceans, Claire A. Dolphin
Post Disturbance Coral Populations: Patterns In Live Cover And Colony Size Classes From Transect Studies In Two Oceans, Claire A. Dolphin
HCNSO Student Theses and Dissertations
This study analyzes data acquired in French Polynesia in the Pacific and The Bahamas (Atlantic), both oceans affected by recent, well documented and sequential disturbances. For the purposes of this study, a disturbance is defined as a perturbation of environmental, physical or biological conditions that causes a distinct change in the ecosystem. After several decades of coral bleaching events, biological change, and anthropogenic impacts, rapid assessments of the coral community were accomplished by collecting photo-transects across the reefs to extract size structure of the corals, percent live tissue cover and perform a faunal evaluation. Cluster analyses and spatial autocorrelation tests …
Diffuse Brain Injury Induces Acute Post-Traumatic Sleep, Rachel K. Rowe, Martin Striz, Adam D. Bachstetter, Linda J. Van Eldik, Kevin D. Donohue, Bruce F. O'Hara, Jonathan Lifshitz
Diffuse Brain Injury Induces Acute Post-Traumatic Sleep, Rachel K. Rowe, Martin Striz, Adam D. Bachstetter, Linda J. Van Eldik, Kevin D. Donohue, Bruce F. O'Hara, Jonathan Lifshitz
Biology Faculty Publications
Objective
Clinical observations report excessive sleepiness immediately following traumatic brain injury (TBI); however, there is a lack of experimental evidence to support or refute the benefit of sleep following a brain injury. The aim of this study is to investigate acute post-traumatic sleep.
Methods
Sham, mild or moderate diffuse TBI was induced by midline fluid percussion injury (mFPI) in male C57BL/6J mice at 9:00 or 21:00 to evaluate injury-induced sleep behavior at sleep and wake onset, respectively. Sleep profiles were measured post-injury using a non-invasive, piezoelectric cage system. In separate cohorts of mice, inflammatory cytokines in the neocortex were quantified …
Volume 51, Number 21: January 08, 2014, University Of North Dakota
Volume 51, Number 21: January 08, 2014, University Of North Dakota
University Letter Archive
No abstract provided.
Milk Consumption And Cardiovascular Risk Factors In Older Chinese: The Guangzhou Biobank Cohort Study, Yangbo Sun, Chaoqiang Jiang, Kar Keung Cheng, Weisen Zhang, Gabriel M. Leung, Tai Hing Lam, Mary Schooling
Milk Consumption And Cardiovascular Risk Factors In Older Chinese: The Guangzhou Biobank Cohort Study, Yangbo Sun, Chaoqiang Jiang, Kar Keung Cheng, Weisen Zhang, Gabriel M. Leung, Tai Hing Lam, Mary Schooling
Publications and Research
Background
Dairy products consumption is increasingly common globally. Most of the evidence concerning dairy products comes from observational studies in western populations which are inevitably open to confounding. To triangulate the evidence concerning dairy products, we examined the associations of whole cow’s milk consumption with cardiovascular risk factors in a non-Western setting with a different pattern of milk consumption and cardiovascular diseases from Western populations.
Methods
We used multivariable censored linear or logistic regression to examine cross-sectionally the adjusted associations of whole cow’s milk consumption (none (n = 14892), 1–3/week (n = 2689) and 3+/week (n = 2754)) with cardiovascular …
Steady Increment Of Immature Platelet Fraction Is Suppressed By Irradiation In Single-Donor Platelet Components During Storage, Hong Hong, Wenbin Xiao, Robert W. Maitta
Steady Increment Of Immature Platelet Fraction Is Suppressed By Irradiation In Single-Donor Platelet Components During Storage, Hong Hong, Wenbin Xiao, Robert W. Maitta
Faculty Scholarship
Circulating immature platelet fraction (IPF) reflects real-time thrombopoiesis and correlates with platelet recovery from thrombocytopenic presentations. To understand the dynamics of IPF in platelet transfusions, we quantified the %-IPF in single-donor platelet components (SDP) during prolonged storage. %-IPF significantly increased from baseline by day 5 post-donation. Absolute IPF counts (A-IPC) had similar significant increments. However, gamma-irradiation suppressed the increments of %-IPF and A-IPC by >50%. Ultrastructural analysis of SDP units at day 10 showed well preserved morphology of immature platelets. Our findings suggest that IPF might actively expand ex-vivo and may have a longer shelf life than their mature counterparts. …
Physical Weight Loading Induces Expression Of Tryptophan Hydroxylase 2 In The Brain Stem., Joon W. Shim, Todd R. Dodge, Max A. Hammond, Joseph M. Wallace, Feng C. Zhou, Hiroki Yokota
Physical Weight Loading Induces Expression Of Tryptophan Hydroxylase 2 In The Brain Stem., Joon W. Shim, Todd R. Dodge, Max A. Hammond, Joseph M. Wallace, Feng C. Zhou, Hiroki Yokota
Weldon School of Biomedical Engineering Faculty Publications
Sustaining brain serotonin is essential in mental health. Physical activities can attenuate mental problems by enhancing serotonin signaling. However, such activity is not always possible in disabled individuals or patients with dementia. Knee loading, a form of physical activity, has been found to mimic effects of voluntary exercise. Focusing on serotonergic signaling, we addressed a question: Does local mechanical loading to the skeleton elevate expression of tryptophan hydroxylase 2 (tph2) that is a rate-limiting enzyme for brain serotonin? A 5 min knee loading was applied to mice using 1 N force at 5 Hz for 1,500 cycles. A 5-min treadmill …
Stochasticity In Natural Forage Production Affects Use Of Urban Areas By Black Bears: Implications To Management Of Human-Bear Conflicts, Sharon Baruch-Mordo, Kenneth R. Wilson, David L. Lewis, John Broderick, Julie S. Mao, Stewart W. Breck
Stochasticity In Natural Forage Production Affects Use Of Urban Areas By Black Bears: Implications To Management Of Human-Bear Conflicts, Sharon Baruch-Mordo, Kenneth R. Wilson, David L. Lewis, John Broderick, Julie S. Mao, Stewart W. Breck
United States Department of Agriculture Wildlife Services: Staff Publications
The rapid expansion of global urban development is increasing opportunities for wildlife to forage and become dependent on anthropogenic resources. Wildlife using urban areas are often perceived dichotomously as urban or not, with some individuals removed in the belief that dependency on anthropogenic resources is irreversible and can lead to increased human-wildlife conflict. For American black bears (Ursus americanus), little is known about the degree of bear urbanization and its ecological mechanisms to guide the management of human-bear conflicts. Using 6 years of GPS location and activity data from bears in Aspen, Colorado, USA, we evaluated the degree of bear …
Ara H 6 Complements Ara H 2 As An Important Marker For Ige Reactivity To Peanut, Audrey E. Koid, Martin D. Chapman, Robert G. Hamilton, Ronald Van Ree, Serge A. Versteeg, Stephen C. Dreskin, Stef J. Koppelman, Sabina Wünschmann
Ara H 6 Complements Ara H 2 As An Important Marker For Ige Reactivity To Peanut, Audrey E. Koid, Martin D. Chapman, Robert G. Hamilton, Ronald Van Ree, Serge A. Versteeg, Stephen C. Dreskin, Stef J. Koppelman, Sabina Wünschmann
Department of Food Science and Technology: Faculty Publications
The similarities of two major peanut allergens, Ara h 2 and Ara h 6, in molecular size, amino acid sequence, and structure have made it difficult to obtain natural Ara h 6 free of Ara h 2. The objectives of this study were to purify natural Ara h 6 that is essentially free of Ara h 2 and to compare its IgE reactivity and potency in histamine release assays to Ara h 2. SDS-PAGE of the highly purified allergen (<0.01% Ara h 2) revealed a single 14.5kD band and the identity of Ara h 6 was confirmed by LC-MS/MS. Ara h 6 showed a higher seroprevalence in chimeric-IgE ELISA (n=54), but a weaker biological activity in basophil histamine release assays than Ara h 2. Purified Ara h 6 will be useful for diagnostic IgE antibody assays, as well as molecular and cellular studies to investigate the immunological mechanisms of peanut allergy.
Hypena Opulenta (Erebidae): A European Species For The Biological Control Of Invasive Swallow-Worts (Vincetoxicum Spp.) In North America, Jim Young, Aaron S. Weed
Hypena Opulenta (Erebidae): A European Species For The Biological Control Of Invasive Swallow-Worts (Vincetoxicum Spp.) In North America, Jim Young, Aaron S. Weed
United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications
The moth Hypena opulenta (Christoph, 1877) (Lepidoptera: Erebidae) was approved for release in eastern Canada and is pending approval in the United States of America as a biological control agent of the invasive European swallow-worts (Vincetoxicum spp.). Descriptions of the adult in Noctuidae Europeae do not accurately represent the color morph of the rearing colony so a new description is provided. Also for the first time the larva is described and illustrated and a simple key is provided that separates H. opulenta from most of the Hypena spp. in the Northeastern U.S.
The Effect Of Retinoic Acid On Rai1 And Identification Of Retinoic Acid Receptor Binding Site In Human Rai1, Bingjie Xue
The Effect Of Retinoic Acid On Rai1 And Identification Of Retinoic Acid Receptor Binding Site In Human Rai1, Bingjie Xue
Theses and Dissertations
Previous studies showed haploinsufficiency of RAI1 is the main cause of Smith-Magenis syndrome (SMS). SMS is a developmental neurobehavioral syndrome characterized by intellectual disability, congenital anomalies, obesity, neurobehavioral abnormalities, and disrupted circadian sleep-wake pattern. SMS is caused by deletion or mutation of chromosomal region 17p11.2 that includes RAI1. Studies in the Elsea lab have shown that RAI1 is a dosage-sensitive gene. Haploinsufficiency of RAI1 leads to dysregulation of CLOCK, NR1D2, POMC, and BDNF, which are responsible for circadian rhythm, metabolism, and cognitive development. Based on the data from Elsea’s recent study on zebrafish, rai1 gene expression in zebrafish is regulated …
Assessing The Optimal Virulence Of Malaria‐Targeting Mosquito Pathogens: A Mathematical Study Of Engineered Metarhizium Anisopliae, Bernhard Konrad, Michael R. Lindstrom, Anja Gumpinger, Jielin Zhu, Daniel Coombs
Assessing The Optimal Virulence Of Malaria‐Targeting Mosquito Pathogens: A Mathematical Study Of Engineered Metarhizium Anisopliae, Bernhard Konrad, Michael R. Lindstrom, Anja Gumpinger, Jielin Zhu, Daniel Coombs
School of Mathematical & Statistical Sciences Faculty Publications
Background
Metarhizium anisopliae is a naturally occurring fungal pathogen of mosquitoes. Recently, Metarhizium has been engineered to act against malaria by directly killing the disease agent within mosquito vectors and also effectively blocking onward transmission. It has been proposed that efforts should be made to minimize the virulence of the fungal pathogen, in order to slow the development of resistant mosquitoes following an actual deployment.
Results
Two mathematical models were developed and analysed to examine the efficacy of the fungal pathogen. It was found that, in many plausible scenarios, the best effects are achieved with a reduced or minimal pathogen …
Being Human: How Four Animals Forever Changed The Way We Live, What We Believe, And Who We Think We Are, Jocelyn Mary Brady
Being Human: How Four Animals Forever Changed The Way We Live, What We Believe, And Who We Think We Are, Jocelyn Mary Brady
Dissertations and Theses
Our lives would not be what they are today without animals. From the food we eat, to the clothes we wear, animals provide tangible evidence of their importance every day. But more than that, animals have shaped who we are and what we believe. Often in ways we don't see.
That's what inspired me to write Being Human. This work began as an examination of how humans have altered animals to better match our imaginations and ideals, and too, the way these animals have irrecoverably altered how we live and look at the world. Consider, for example, that before they …
Resveratrol Induces Vascular Smooth Muscle Cell Differentiation Through Stimulation Of Sirt1 And Ampk, Anne Marie Thompson, Kathleen A. Martin, Eva M. Rzucidlo
Resveratrol Induces Vascular Smooth Muscle Cell Differentiation Through Stimulation Of Sirt1 And Ampk, Anne Marie Thompson, Kathleen A. Martin, Eva M. Rzucidlo
Dartmouth Scholarship
Phenotypic plasticity in vascular smooth muscle cells (VSMC) is necessary for vessel maintenance, repair and adaptation to vascular changes associated with aging. De-differentiated VSMC contribute to pathologies including atherosclerosis and intimal hyperplasia. As resveratrol has been reported to have cardio- protective effects, we investigated its role in VSMC phenotypic modulation. We demonstrated the novel finding that resveratrol promoted VSMC differentiation as measured by contractile protein expression, contractile morphology and contraction in collagen gels. Resveratrol induced VSMC differentiation through stimulation of SirT1 and AMPK. We made the novel finding that low or high dose resveratrol had an initially different mechanism on …