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2014

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Orientation-Based Persecution As Grounds For Refugee Status: Policy Implications And Recommendations, Julia Blanche Meister Feb 2014

Orientation-Based Persecution As Grounds For Refugee Status: Policy Implications And Recommendations, Julia Blanche Meister

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.


The Case For Gay Marriage, Richard D. Mohr Feb 2014

The Case For Gay Marriage, Richard D. Mohr

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.


Biochemical Characterization Of The Estrogen Receptor Alpha (Erα) Coactivator E6-Ap, Skp2 And Fbxl6, Wen Zhou Feb 2014

Biochemical Characterization Of The Estrogen Receptor Alpha (Erα) Coactivator E6-Ap, Skp2 And Fbxl6, Wen Zhou

Open Access Dissertations

Many transcription factors undergo transcription-coupled proteolysis. While ligand binding activates ubiquitin-proteolysis of estrogen receptor alpha (ER), mechanisms governing this and its relationship to transcriptional activation were unclear. In this thesis, I present the evidence indicating that different ubiquitin ligases, including E6-AP and SCF/SKP2 regulate ER protein stability and transcriptional activity. SKP2 project support a model in which estrogen-activated CyclinE-CDK2 binds and phosphorylates ER-S341, to prime ER-SCF/SKP2 binding via SKP2-L248QTLL252 in late G1. SKP2 activates ER ubiquitylation and proteolysis. Putative late ER targets were identified by expression profiling, SKP2 knockdown attenuated E2F-1 and BLM induction. SKP2 overexpression, but not coactivator motif …


The Gazette February 5, 2014, Langston University Feb 2014

The Gazette February 5, 2014, Langston University

LU Gazette, 2010-2019

The student newspaper for Langston University


The Cord (February 5, 2014) Feb 2014

The Cord (February 5, 2014)

The Cord

No abstract provided.


An Experimental Study Of Strong Reciprocity In Bacteria, R. Inglis, R. Inglis, Stuart West, Angus Buckling Feb 2014

An Experimental Study Of Strong Reciprocity In Bacteria, R. Inglis, R. Inglis, Stuart West, Angus Buckling

Biology Department Faculty Works

Strong reciprocity, whereby cooperators punish non-cooperators, may help to explain the evolutionary success of cooperative behaviours. However, theory suggests that selection for strong reciprocity can depend upon tight genetic linkage between cooperation and punishment, to avoid the strategy being outcompeted by non-punishing cooperators. We tested this hypothesis using experimental populations of the bacterium Pseudomonas aeruginosa, which cooperate by producing iron-scavenging siderophores and, in this context, punish non-cooperators with toxins. Consistent with theory, we show that cooperative punishers can indeed invade cheats, but only when the traits are tightly linked. These results emphasize that punishment is only likely to be favoured …


A Conceptual Framework For Clutch-Size Evolution In Songbirds, Thomas E. Martin Feb 2014

A Conceptual Framework For Clutch-Size Evolution In Songbirds, Thomas E. Martin

Wildlife Biology Faculty Publications

Causes of evolved differences in clutch size among songbird species remain debated. I propose a new conceptual framework that integrates aspects of traditional life-history theory while including novel elements to explain evolution of clutch size among songbirds. I review evidence that selection by nest predation on length of time that offspring develop in the nest creates a gradient in offspring characteristics at nest leaving (fledging), including flight mobility, spatial dispersion, and self-feeding rate. I postulate that this gradient has consequences for offspring mortality rates and parental energy expenditure per offspring. These consequences then determine how reproductive effort is partitioned among …


We Are...Marshall, February 5, 2014, Office Of Marshall University Communications Feb 2014

We Are...Marshall, February 5, 2014, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.


The Winonan, Winona State University Feb 2014

The Winonan, Winona State University

The Winonan - 2010s

No abstract provided.


Copy Number Variation In Chickens: A Review And Future Prospects, Xiaofei Wang, Shannon Byers Feb 2014

Copy Number Variation In Chickens: A Review And Future Prospects, Xiaofei Wang, Shannon Byers

Biology Faculty Research

DNA sequence variations include nucleotide substitution, deletion, insertion, translocation and inversion. Deletion or insertion of a large DNA segment in the genome, referred to as copy number variation (CNV), has caught the attention of many researchers recently. It is believed that CNVs contribute significantly to genome variability, and thus contribute to phenotypic variability. In chickens, genome-wide surveys with array comparative genome hybridization (aCGH), SNP chip detection or whole genome sequencing have revealed a large number of CNVs. A large portion of chicken CNVs involves protein coding or regulatory sequences. A few CNVs have been demonstrated to be the determinant factors …


Science Café | Nanoscience Playing Soccer With Atoms And Molecules, Feb 5, Ohio University College Of Arts & Sciences Feb 2014

Science Café | Nanoscience Playing Soccer With Atoms And Molecules, Feb 5, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.


Dessa Rose (2014), Lynn Ahren Feb 2014

Dessa Rose (2014), Lynn Ahren

Season 2014-2015

No abstract provided.


Campus Chronicle, Alex Payne, Jesse Garwick, Martina Gutierrez, Logan Lantz, Miriah Masching, Morgan Meier, Megan Miras, Alex Roth, Courtney Swessinger, Andy Langager Feb 2014

Campus Chronicle, Alex Payne, Jesse Garwick, Martina Gutierrez, Logan Lantz, Miriah Masching, Morgan Meier, Megan Miras, Alex Roth, Courtney Swessinger, Andy Langager

Campus Chronicle

No abstract provided.


February 5, 2014 Faculty Senate Minutes, University Of South Carolina Feb 2014

February 5, 2014 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.


The Daily Egyptian, February 05, 2014, Daily Egyptian Staff Feb 2014

The Daily Egyptian, February 05, 2014, Daily Egyptian Staff

February 2014

No abstract provided.


The Evolutionary Function Of Conscious Information Processing Is Revealed By Its Task-Dependency In The Olfactory System, Andreas Keller Feb 2014

The Evolutionary Function Of Conscious Information Processing Is Revealed By Its Task-Dependency In The Olfactory System, Andreas Keller

Publications and Research

Although many responses to odorous stimuli are mediated without olfactory information being consciously processed, some olfactory behaviors require conscious information processing. I will here contrast situations in which olfactory information is processed consciously to situations in which it is processed non-consciously. This contrastive analysis reveals that conscious information processing is required when an organism is faced with tasks in which there are many behavioral options available. I therefore propose that it is the evolutionary function of conscious information processing to guide behaviors in situations in which the organism has to choose between many possible responses.


The Guardian, February 5, 2014, Wright State University Student Body Feb 2014

The Guardian, February 5, 2014, Wright State University Student Body

The Guardian Student Newspaper

Twelve page issue of The Guardian, the official student-run newspaper for Wright State University. The Guardian has been published regularly since March of 1965.


Volume 51, Number 25: February 05, 2014, University Of North Dakota Feb 2014

Volume 51, Number 25: February 05, 2014, University Of North Dakota

University Letter Archive

No abstract provided.


Cwu Faculty Senate Minutes - 02/05/14, Janet Shields Feb 2014

Cwu Faculty Senate Minutes - 02/05/14, Janet Shields

Faculty Senate Minutes

These are the official Central Washington University Faculty Senate minutes for the 02/05/14 meeting.


Variable Facial Plumage In Juvenile Cliff Swallows: A Potential Offspring Recognition Cue?, Allison E. Johnson, Steven Freedberg Feb 2014

Variable Facial Plumage In Juvenile Cliff Swallows: A Potential Offspring Recognition Cue?, Allison E. Johnson, Steven Freedberg

School of Biological Sciences: Faculty Publications

Although the ability to recognize related offspring is essential in the evolution of social behavior, the cues that birds use to identify their own offspring are not fully understood. The Cliff Swallow (Petrochelidon pyrrhonota) is a highly social species that nests in large colonies and exhibits a high incidence of both conspecific brood parasitism and extrapair fertilization, behaviors that can potentially lead to parents investing energy and resources in unrelated offspring, which reduces the parents’ genetic fitness. Because parents continue to feed offspring after they leave the nest, parents also risk investing in unrelated offspring by misidentifying their …


Influence Networks Based On Coexpression Improve Drug Target Discovery For The Development Of Novel Cancer Therapeutics, Nadia M. Penrod, Jason H. Moore Feb 2014

Influence Networks Based On Coexpression Improve Drug Target Discovery For The Development Of Novel Cancer Therapeutics, Nadia M. Penrod, Jason H. Moore

Dartmouth Scholarship

Background: Thedemandfornovelmolecularlytargeteddrugswillcontinuetoriseaswemoveforwardtowardthe goal of personalizing cancer treatment to the molecular signature of individual tumors. However, the identification of targets and combinations of targets that can be safely and effectively modulated is one of the greatest challenges facing the drug discovery process. A promising approach is to use biological networks to prioritize targets based on their relative positions to one another, a property that affects their ability to maintain network integrity and propagate information-flow. Here, we introduce influence networks and demonstrate how they can be used to generate influence scores as a network-based metric to rank genes as potential drug targets. …


The Bg News February 05, 2014, Bowling Green State University Feb 2014

The Bg News February 05, 2014, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. February 05, 2014. Volume 93-Issue 61.


Induction Of Autophagy Restores The Loss Of Sevoflurane Cardiac Preconditioning Seen With Prolonged Ischemic Insult., Mayumi Shiomi, Masami Miyamae, Genzou Takemura, Kazuhiro Kaneda, Yoshitaka Inamura, Anna Onishi, Shizuka Koshinuma, Yoshihiro Momota, Toshiaki Minami, Vincent M. Figueredo, M.D. Feb 2014

Induction Of Autophagy Restores The Loss Of Sevoflurane Cardiac Preconditioning Seen With Prolonged Ischemic Insult., Mayumi Shiomi, Masami Miyamae, Genzou Takemura, Kazuhiro Kaneda, Yoshitaka Inamura, Anna Onishi, Shizuka Koshinuma, Yoshihiro Momota, Toshiaki Minami, Vincent M. Figueredo, M.D.

Division of Cardiology Faculty Papers

Sevoflurane preconditioning against myocardial ischemia-reperfusion injury is lost if the ischemic insult is too long. Emerging evidence suggests that induction of autophagy may also confer cardioprotection against ischemia-reperfusion injury. We examined whether induction of autophagy prolongs sevoflurane preconditioning protection during a longer ischemic insult. Isolated guinea pigs hearts were subjected to 30 or 45 min ischemia, followed by 120 min reperfusion (control). Anesthetic preconditioning was elicited with 2% sevoflurane for 10 min prior to ischemia (SEVO-30, SEVO-45). Chloramphenicol (autophagy upregulator, 300 µM) was administered starting 20 min before ischemia and throughout reperfusion in SEVO-45 (SEVO-45+CAP). To inhibit autophagy, 3-methyladenine (10 …


Contrast Enhancement Using Silica Microspheres In Coherent Anti-Stokes Raman Spectroscopic Imaging, X. Huang, X. N. He, W. Xiong, Y. Gao, L. J. Jiang, Li Liu, Y. S. Zhou, L. Jiang, J. F. Silvain, Yongfeng Lu Feb 2014

Contrast Enhancement Using Silica Microspheres In Coherent Anti-Stokes Raman Spectroscopic Imaging, X. Huang, X. N. He, W. Xiong, Y. Gao, L. J. Jiang, Li Liu, Y. S. Zhou, L. Jiang, J. F. Silvain, Yongfeng Lu

Department of Electrical and Computer Engineering: Faculty Publications

Coherent anti-Stokes Raman scattering (CARS) microscopy is a powerful imaging technique that can provide chemical information of organic and nonorganic materials through vibrational spectroscopy. However, its contrast is not sufficient for monitoring thin film materials. In this study, silica microspheres were employed for enhancing the signal contrast in CARS imaging. One layer of optically transparent silica microspheres was self-assembled onto polymer grating samples to enhance the CARS signals. The highest contrast enhancement factor of 12.5 was achieved using 6.1-μm-diameter microspheres. Finite-difference timedomain method (FDTD) simulation was conducted to simulate the contrast enhancement with silica microspheres of different diameters.


Hotline Press Newspaper Febraury 5, 2014 Vol 29 No 38, Hotline Press Newspaper Feb 2014

Hotline Press Newspaper Febraury 5, 2014 Vol 29 No 38, Hotline Press Newspaper

Hotline Press Newspaper 2014

No abstract provided.


Communicating In A Socially-Aware Network: Impact Of Relationship Types, Basak Guler, Burak Varan, Kaya Tutuncuoglu, Mohamed Nafea, Ahmed A. Zewail, Aylin Yener, Damien Octeau Feb 2014

Communicating In A Socially-Aware Network: Impact Of Relationship Types, Basak Guler, Burak Varan, Kaya Tutuncuoglu, Mohamed Nafea, Ahmed A. Zewail, Aylin Yener, Damien Octeau

Electrical and Computer Engineering Faculty Research & Creative Works

Communication networks are linked to and influenced by human interactions. Socially aware systems should integrate these complex relationship patterns in the network design. This paper studies the impact of friendship and antagonistic relationships between individuals on optimal network propagation policies. We develop a network propagation model for signed networks and determine the optimal policies to influence a target node with an opinion while minimizing the total number of persons against it. We also provide extensions to this problem to elaborate on the impact of network parameters, such as minimum-delay propagation, while limiting the number of persons influenced against the idea …


Monarch Butterfly Populations At Biosphere In Michoacã¡N Down Sharply, Carlos Navarro Feb 2014

Monarch Butterfly Populations At Biosphere In Michoacã¡N Down Sharply, Carlos Navarro

SourceMex

No abstract provided.


The Abcs Of The Ribosome, Kurt Fredrick, Michael Ibba Feb 2014

The Abcs Of The Ribosome, Kurt Fredrick, Michael Ibba

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

An ABC protein that binds the ribosomal exit site suggests a new mechanism for direct regulation of translation in response to changing ATP levels in the cell.


Compounds And Methods For Reducing Oxidative Stress, Thomas Dziubla, J. Zach Hilt, Dipti Biswal, David B. Cochran, Paritosh Wattamwar Feb 2014

Compounds And Methods For Reducing Oxidative Stress, Thomas Dziubla, J. Zach Hilt, Dipti Biswal, David B. Cochran, Paritosh Wattamwar

Chemical and Materials Engineering Faculty Patents

Antioxidant polymeric compounds are provided that comprise a plurality of monomeric portions, where each monomeric portion includes an antioxidant molecule interposed between at least two acrylate molecules, and where at least one acrylate molecule of each monomeric portion is linked by a diamine molecule to an acrylate molecule of an adjacent monomeric portion to thereby form the polymer. Methods of synthesizing polymeric compounds and methods of using the antioxidant polymeric compounds to reduce oxidative stress are also provided.


Minutes, Arts & Sciences Professional Standards Committee Meeting, Tuesday, February 4, 2014, Arts & Sciences Professional Standards Committee Feb 2014

Minutes, Arts & Sciences Professional Standards Committee Meeting, Tuesday, February 4, 2014, Arts & Sciences Professional Standards Committee

Professional Standards Committee Minutes

No abstract provided.