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Clubs - Morehead, Jack D. Ellis

Jack D. Ellis Rowan County History Collection

No abstract provided.

Democratic Deliberation And The Ethical Review Of Human Subjects Research, Govind Persad

Sturm College of Law: Faculty Scholarship

In the United States, the Presidential Commission for the Study of Bioethical Issues has proposed deliberative democracy as an approach for dealing with ethical issues surrounding synthetic biology. Deliberative democracy might similarly help us as we update the regulation of human subjects research. This paper considers how the values that deliberative democratic engagement aims to realize can be realized in a human subjects research context. Deliberative democracy is characterized by an ongoing exchange of ideas between participants, and an effort to justify decisions that bind participants by appeal to reasons that the participants can understand and share. Even when unanimous …

You Are What You Eat, Or Are You? The Challenges Of Translating High-Fat-Fed Rodents To Human Obesity And Diabetes, M. Lai, P. C. Chandrasekera, Neal D. Barnard

Medicine Faculty Publications

Obesity and type 2 diabetes mellitus (T2DM) are rapidly growing worldwide epidemics with major health consequences. Various human-based studies have confirmed that both genetic and environmental factors (particularly high-caloric diets and sedentary lifestyle) greatly contribute to human T2DM. Interactions between obesity, insulin resistance and β-cell dysfunction result in human T2DM, but the mechanisms regulating the interplay among these impairments remain unclear. Rodent models of high-fat diet (HFD)-induced obesity have been used widely to study human obesity and T2DM. With >9000 publications on PubMed over the past decade alone, many aspects of rodent T2DM have been elucidated; however, correlation to human …

Thiamine Pyrophosphokinase Deficiency Causes A Leigh Disease Like Phenotype In A Sibling Pair: Identification Through Whole Exome Sequencing And Management Strategies, Jamie L. Fraser, Adeline Vanderver, Sandra Yang, Taeun Chang, Laura Cramp, Gilbert Vezina, Uta Lichter-Konecki, Kristina Cusmano-Ozog, Patroula Smpokou, Kimberly A. Chapman, Dina Zand

Medicine Faculty Publications

We present a sibling pair with Leigh-like disease, progressive hypotonia, regression, and chronic encephalopathy. Whole exome sequencing in the younger sibling demonstrated a homozygous thiamine pyrophosphokinase (TPK) mutation. Initiation of high dose thiamine, niacin, biotin, α-lipoic acid and ketogenic diet in this child demonstrated improvement in neurologic function and re-attainment of previously lost milestones. The diagnosis of TPK deficiency was difficult due to inconsistent biochemical and diagnostic parameters, rapidity of clinical demise and would not have been made in a timely manner without the use of whole exome sequencing. Molecular diagnosis allowed for attempt at dietary modification with cofactor supplementation …

Nutrition Intervention For Migraine: A Randomized Crossover Trial, Anne E. Bunner, Ulka Agarwal, Joseph F. Gonzales, Francesca Valente, Neal D. Barnard

Medicine Faculty Publications

Background

Limited evidence suggests that dietary interventions may offer a promising approach for migraine. The purpose of this study was to determine the effects of a low-fat plant-based diet intervention on migraine severity and frequency.

Methods

Forty-two adult migraine sufferers were recruited from the general community in Washington, DC, and divided randomly into two groups. This 36-week crossover study included two treatments: dietary instruction and placebo supplement. Each treatment period was 16 weeks, with a 4-week washout between. During the diet period, a low-fat vegan diet was prescribed for 4 weeks, after which an elimination diet was used. Participants were …

Meat Consumption As A Risk Factor For Type 2 Diabetes, Neal D. Barnard, Susan Levin, Caroline Trapp

Medicine Faculty Publications

Disease risk factors identified in epidemiological studies serve as important public health tools, helping clinicians identify individuals who may benefit from more aggressive screening or risk-modification procedures, allowing policymakers to prioritize intervention programs, and encouraging at-risk individuals to modify behavior and improve their health. These factors have been based primarily on evidence from cross-sectional and prospective studies, as most do not lend themselves to randomized trials. While some risk factors are not modifiable, eating habits are subject to change through both individual action and broader policy initiatives. Meat consumption has been frequently investigated as a variable associated with diabetes risk, …

Wonder Drugs To Hot New Diets: Knowledge Is Power! Adult Health Literacy, Adnan Ahmeduddin, Mary Grace Bowring, Kelly Davis, Indra Gomez, Sarah Halle, Courtney Middlebrook, Molly Sadowsky, Lauren Shauger, Lauren Violette

ISCOPES Posters and Presentations

No abstract provided.

Cross-Sectional Association Between The Number Of Missing Teeth And Cardiovascular Disease Among Adults Aged 50 Or Older: Brfss 2010, R Constance Wiener

Faculty & Staff Scholarship

Objective. The relationship between oral health and cardiovascular disease is an emerging area of research. The objective of the current study is to evaluate the association of cardiovascular disease and the number of missing teeth as a risk indicator. Methods. Cross-sectional study design with data on 275,424 respondents aged 50 or older from the 2010 Behavioral Risk Factor Surveillance System survey was used. The dependent variable was self-reported cardiovascular disease. The association between the number of missing teeth and cardiovascular disease was analyzed with multivariable logistic regression. The regression was adjusted for sex, race/ethnicity, age, education, income, dental visits, smoking …

Betting On Bowlers: This Just Isn't Cricket, Erin Gardner Schenk

Denver Journal of International Law & Policy

No abstract provided.

Short And Long-Term Lifestyle Coaching Approaches Used To Address Diverse Participant Barriers To Weight Loss And Physical Activity Adherence, Elizabeth M. Venditti, Judith Wylie-Rosett, Linda M. Delahanty, Lisa L. Mele, Mary A. Hoskin, Sharon Edelstein

GW Biostatistics Center

Background

Individual barriers to weight loss and physical activity goals in the Diabetes Prevention Program, a randomized trial with 3.2 years average treatment duration, have not been previously reported. Evaluating barriers and the lifestyle coaching approaches used to improve adherence in a large, diverse participant cohort can inform dissemination efforts.

Methods

Lifestyle coaches documented barriers and approaches after each session (mean session attendance = 50.3 +/- 21.8). Subjects were 1076 intensive lifestyle participants (mean age = 50.6 years; mean BMI = 33.9 kg/m2; 68% female, 48% non-Caucasian). Barriers and approaches used to improve adherence were ranked by the percentage of …

Cardiometabolic Risk Assessments By Body Mass Index Z-Score Or Waist-To-Height Ratio In A Multiethnic Sample Of Sixth-Graders, Henry S. Kahn, Laure El Ghormli, Russell Jago, Gary D. Foster, Robert G. Mcmurray, John B. Buse, Diane D. Stadler, Roberto P. Trevino, Tom Baranowski, Healthy Study Group

GW Biostatistics Center

Convention defines pediatric adiposity by the body mass index -score (BMIz) referenced to normative growth charts. Waist-to-height ratio (WHtR) does not depend on sex-and-age references. In the HEALTHY Study enrollment sample, we compared BMIz with WHtR for ability to identify adverse cardiometabolic risk. Among 5,482 sixth-grade students from 42 middle schools, we estimated explanatory variations (R²) and standardized beta coefficients of BMIz or WHtR for cardiometabolic risk factors: insulin resistance (HOMA-IR), lipids, blood pressures, and glucose. For each risk outcome variable, we prepared adjusted regression models for four subpopulations stratified by sex and high versus lower fatness. …

Himmelfarb Library Annual Report 2014, George Washington University, Himmelfarb Health Sciences Library

Himmelfarb Library Annual Report

No abstract provided.

The Constitutive Nature Of Non-Profit Advertising And Its Effect On Agency: An Analysis Of The Campaigns Of Childfund International And (Red), Camry Martinez

Honors Theses, 1963-2015

Many rhetorical scholars choose to study the persuasive effectiveness of an advertisement instead of the reality that the ad creates. While this is a beneficial endeavor, in the case of non-profit advertisements it allows for the meaning the advertisements create to be passed over. The meaning is assumed to be positive because the effect of the successful persuasion of the ad results in a beneficial outcome, helping others. The literature review examines rhetoric as constitutive, or capable of creating the meaning of the audience, and then explores how through this constitutive nature an advertisement can affect the agency of an …

Agricultural Research Magazine, Vol. 62, No. 1, January 2014, United States Department Of Agriculture

Agricultural Research Magazine

Forum-Success in Controlling Some Cotton Pests Opens the Door to Others

Diverse Approaches To Tame an Emerging Pest

Mulching and Guar Gum: Substitutes for This Familiar "Binder" Tested

Flower Power Protects Organic Lettuce Fields

Specialty Greens Pack a Nutritional Punch

Pampering Anjou: Studying Storage of a Popular Pear

Chickens Open Wide for Gelatin Bead Vaccine

National Inventory Takes Stock of Crops' Wild Relatives

New Rice Naturally Fends Off Weeds

Locations Featured in This Magazine Issue

Agricultural Research Magazine, Vol. 62, No. 2, February 2014, United States Department Of Agriculture

Agricultural Research Magazine

Forum—Building on the Basics About Soil Carbon A Surprising Supply of Deep Soil Carbon Potatoes Show Promise for Meeting Climate Change Challenges New Tool for Improving Soybeans Test Strip Quickly Detects Botulism-Causing Toxins Taking Purées to a New Level Obesity During Pregnancy: Scientists Explore Impacts on Baby's Bone Health Aspirin-Like Compound Primes Plant Defense Against Pathogens Myelin Matters to Piglet Movement, Reflexes, and Coordination Locations Featured in This Magazine Issue

Agricultural Research Magazine, Vol. 62, No. 3, March 2014, United States Department Of Agriculture

Agricultural Research Magazine

Forum—Fighting Diseases That Threaten the Poultry Industry Reducing the Threat of Exotic Avian Diseases Safer Eggs: New Technique Uses Radio Waves to Zap Salmonella What Makes an Avocado Delicious? Scientists Seek Clues to Fruit's Flavor Cleaning Honeycombs With Ozone Dietary Products: Some are Underresearched, Overmarketed Coats Protect Seeds Planted in Cold, Wet Soils Probiotics for Pigs: Less Manure, Better Health New Reference Provides Uses and Origins of Economically Important Plants Locations Featured in This Magazine Issue

Agricultural Research Magazine, Vol. 62, No. 4, April 2014, United States Department Of Agriculture

Agricultural Research Magazine

Forum-ARS Plays an Integral Role in Combating a Virulent Threat Targeting Pheromones in Fire Ants Male Chromosome Hinders Female Cattle Reproduction Nitrite Significant Role in Nitrous Oxide Emissions from Soil New-and More Economical-Pyrolysis Techniques for Bio-oil Production New Ornamental Tung Tree a Story of Loss and Restorations Fighting a Pernicious Weed with Fire Looking to Wheat's Wild Ancestors to Solve a Modern Problem Locations Featured in This Magazine Issue New Food Ingredient from Rice Bran Oil May Help Make Foods’ Fat Profile More Healthful

Agricultural Research Magazine, Vol. 62, No. 5, May/June 2014, United States Department Of Agriculture

Agricultural Research Magazine

Forum—Valuing U.S. Agriculture Identifying Yellow Perch Gender to Improve Production "Supershedders" Role in Spreading E. coli Scrutinized Transparent Coating for Glass, Plastics—and More—May Have Bright Future Foraging Worms Guarantee Slug Bait Failure Dissecting a Potato Pathogen's Hiding Place in Its Insect Vector Advance May Speed Development of Seed Rot-Resistant Soybeans Taming Extreme Environments by Exploring Algae in Space Pigs Useful in Immune and Obesity Research Controlling Odors and Greenhouse Gas Emissions from Stored Swine Manure New Class of Animal Deworming Agent Locations Featured in This Magazine Issue

Agricultural Research Magazine, Vol. 62, No. 6, July 2014, United States Department Of Agriculture

Agricultural Research Magazine

Forum—Enhancing Food Safety by Supporting Regulatory Agencies and Industry A Lab That Keeps Us All Out of a Pickle Genetic Mapping of Rust-resistance Genes in Sunflower Orange-Fleshed Honeydew Melon: Ripe for Beta-Carotene Analysis Making a Barley Fish Feed Product Details Matter in Modeling Carbon Sequestration and Cropping Systems Reducing Fertilizer Needs by Accounting for Soil Microbes Data Analyses Show How Weather Patterns Can Affect Cattle Production Whacking Weeds Organically Treatment Has Potential to Reduce Allergenicity of Peanuts Locations Featured in This Magazine Issue

Agricultural Research Magazine, Vol. 62, No, 9, October 2014, United States Department Of Agriculture

Agricultural Research Magazine

Forum-Keeping Pace with Agriculture's Challenges New Imaging Techniques Leads to Better Understanding of Freezing in Plants Better Information for Improved Beef Manure Management Improving Trout Resistance to a Deadly Disease Pest's Taster for Fine Wine May Prove Its Undoing Mandarin Oranges: Protecting the Flavor of This Popular Fruit Experimental Website Helps Teens Eat More Veggies Latest Update of USDA's Nutrient Database Released The Greatest Show on Turf Assessing Cotton Fiber Quality From a Tiny Sample A Steady Pace of Cellulosic Ethanol Research in Peoria Using Location Information to Improve Literature Searches Locations Featured in This Magazine Issue

Agricultural Research Magazine, Vol. 62, No. 10, November/December 2014, United States Department Of Agriculture

Agricultural Research Magazine

Forum-The Never Ending Insect Control Contest Fire Ants Are No Match for Poison Frogs Controlling Native Stink Bugs in the Southeast Closing in on Butanol for Biofuel Assessing the Ricks of HoBi-like Virus in Cattle Making Peach Trees Fit Better on the Field Finding Rice Traits That Tackle Climate-change Challenges New Test Count Total Phenolics in Fruits and Vegetables Delicious, Nutritious, and a Colorful Dish for the Holidays! Markers Highlight the Way to Disease Resistance in Peas Your Brain and Comfort Foods: Neuroimages Capture Effect Locations Featured in This Magazine Issue

Kin 248.01: Principles Of Optimal Performance For Athletes, Charles G. Palmer

University of Montana Course Syllabi

No abstract provided.

Ahhs 420.01: Geriatric Health Issues, Gayle A. Hudgins

University of Montana Course Syllabi

No abstract provided.

Descriptive Sensory Analysis And Composition Of Blackberry Genotypes, Bethany Sebesta

Inquiry: The University of Arkansas Undergraduate Research Journal

Consumer interest in blackberries has been increasing due in part to reputed health-promoting factors. Appearance, flavor, and texture attributes of blackberry fruits are important to consumers. The objective of this study was to investigate correlations among sensory and composition attributes of blackberry genotypes from the University of Arkansas Division of Agriculture breeding program. Descriptive panelists evaluated attributes of 20 blackberry genotypes. Composition attributes were evaluated for these and two additional genotypes. ‘Natchez’ had the most pyrenes/berry and the highest levels of total ellagitannins. Selection A-2215 was scored highest for descriptive-evaluated sweetness and had the highest soluble solids content. Total ellagitannins …

Baystate Medical Center Nursing Report - 2014/2015, Christine Klucznik Dnp, Rn

Baystate Medical Center Nursing Report

Baystate Medical Center Nursing Report - 2014/2015

Motivation In Synchronous Hybrid Graduate Business Programs: A Self-Determination Approach To Contrasting Online And On-Campus Students, Nikolaus T. Butz, Robert H. Stupnisky, Erin S. Peterson, Melissa M. Majerus

Education, Health & Behavior Studies Faculty Publications

determination theory; graduate business education

Short-Stay, Under Observation, Or Inpatient Admission?—How Cms’ Two Midnight Rule Creates More Confusion & Concern, Rachel A. Polzin

Saint Louis University Journal of Health Law & Policy

No abstract provided.

Fitness In Animals Correlates With Proximity To Discontinuities In Body Mass Distributions, David G. Angeler, Craig R. Allen, Anna Vila-Gispert, David Almeida

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Discontinuous structure in landscapes may cause discontinuous, aggregated species body-mass patterns, reflecting the scales of structure available to animal communities within a landscape. Empirical analyses have shown that the location of species within body mass aggregations, which reflect this scalespecific organization, is non-random with regard to several ecological phenomena, including species extinctions. The propensity of declining species to have body masses proximate to discontinuities suggests that transition zones between scaling regimes ultimately decreases the ecological fitness for some species. We test this proposition using vulnerable and unthreatened fish species in Mediterranean streams with differing levels of human impact. We show …

Defining Collaborative Science In An Age Of Translational Medicine, Gaetano R. Lotrecchiano

Clinical Research and Leadership Faculty Publications

No abstract provided.

Review Of Hyperuricemia As New Marker For Metabolic Syndrome, Laura Billiet, Sarah Doaty, James D. Katz, Manuel T. Velasquez

Global Health Faculty Publications

Hyperuricemia has long been established as the major etiologic factor in gout. In recent years, a large body of evidence has accumulated that suggests that hyperuricemia may play a role in the development and pathogenesis of a number of metabolic, hemodynamic, and systemic pathologic diseases, including metabolic syndrome, hypertension, stroke, and atherosclerosis. A number of epidemiologic studies have linked hyperuricemia with each of these disorders. In some studies, therapies that lower uric acid may prevent or improve certain components of the metabolic syndrome. There is an association between uric acid and the development of systemic lupus erythematosus; the connection between …