Digital Commons Network^™

Investigating The Effects Of Biochemical And Biophysical Signals On Vascular Smooth Muscle Cell Differentiation, Ruikai Chen

All Dissertations

In blood vessel engineering, an optimal bioartifical scaffold can be characterized as a 3D tubular structure with high porosity for nutrient diffusion and enough mechanical strength to sustain in vivo dynamic environment. The luminal surface of the scaffold is supposed to have a continuous layer of endothelial cell that is ideally non-immunogenic and non-thrombogenic while the media layer of the construct is assigned for the ingrowth of vascular smooth muscle cell which can provide structural integrity and contractility. While reconstructing endothelial cell layer has been at the center of interest in most polymeric vascular replacements related research, growing VSMCs has …

Perceived Health Status, Health Values And Health Goals As Influences On Individual Pursuit Of Dtc Genome Testing: Implications For Healthcare Of Ill & Healthy, Carolyn Marie Dachs Farrell

All Dissertations

This dissertation examines an individual’s perceived health status, and health values, as influences on self-initiated health action, specifically the pursuit of Direct-to-consumer (DTC) genome testing. Motivation for this independent health action may also have implications for other individual health behaviors, including the potential for positive changes that are lasting rather than temporary. Health Capability, the conceptual framework, supports individual health values and goals, ability to access valued healthcare services and includes measures of health status. However, Health Capability lacks an operationalized mapping of its major concepts. This dissertation proposes and evaluates an original concept mapping and relationships. An overview of …

Structure-Property Relationship Of Nanomodified Mesophase Pitch-Based Carbon Fibers, Rebecca Marie Alway Cooper

All Dissertations

Mesophase pitch-based carbon fibers are known for their excellent thermal and electrical conductivity, high tensile modulus, moderate tensile strength, but poor compressive strength. This collection of properties results from the texture and crystalline structure (together known as microstructure) of the fibers. Fiber microstructure, in turn, develops during processing due to the discotic nature of the mesophase pitch precursor. In prior studies, such important parameters as the size and shape of capillaries in the spinneret, spinning temperature and carbonization temperature have been varied to produce fibers with different microstructures and properties. In this dissertation, the primary research goal was to investigate …

The Effects Of Secondary Trapping Mechanisms On Geologic Storage Of Carbon Dioxide, Catherine Ruprecht

All Dissertations

The goal of this Dissertation is to further the understanding of secondary trapping mechanisms in geologic CO₂ storage systems to improve storage design and security. This Dissertation takes the form of three chapters. The objective of the first chapter was to analyze the storage performance of supercritical and brine saturated CO₂ injection strategies to determine their advantages and disadvantages on distribution and immobilization of CO₂ and pressure buildup. Results showed dissolved CO₂ injection was favorable in terms of storage security in all cases as it resulted in smaller areal extents on the caprock and did not …

Consumer Acceptance And Willingness To Pay For Genetically Modified Rice In China: A Double Bounded Dichotomous Choic Contingent Valuation Survey Calibrated By Cheap Talk, Jing Jin

Graduate Theses and Dissertations

Considering population growth, limitations on land and water resources, and contamination to the ecosystem due to agricultural activities, current rice production in China is facing pressure to fulfill national demand. Self-sufficiency of rice has been a long-held political objective of the Chinese government and it is national goal to maintain the equilibrium between the national production and consumption or even achieve a supply surplus in rice. With the developing bio-technology of genetic modification (GM), scientists believe that using genetically modified cultivars may ease the pressure mentioned above. However, both the government and the people are very cautious about large-scale cultivation …

Managing Devil Facial Tumour Disease In Tasmanian Devils (Sarcophilus Harrisii): An Investigation Of Heat Shock Proteins As Potential Vaccine Adjuvants, Monika Payerhin

Independent Study Project (ISP) Collection

The world’s largest carnivorous marsupial, the Tasmanian devil (Sarcophilus harrisii), is facing extinction from a deadly, highly communicable cancer that has already decimated over 85% of devil populations in the wild: devil facial tumour disease (DFTD). DFTD cells effectively evade recognition by the immune system, and every devil that contracts the disease dies from it. Many attempts have been made at developing a vaccine that could help save this now-threatened species. Heat shock proteins have been linked to enhanced immune recognition of pathogens, making them potential candidates for acting as adjuvants to such a vaccine against DFTD. In this study, …

Premature Births And Maternal Health: An Analysis Of Risk Factors That Affect The Rate Of Prematurity / Los Nacimientos Prematuros Y La Salud Materna: Un Análisis De Los Factores De Riesgo Que Afecta La Tasa De Prematuridad, Alexandria Mickler

Independent Study Project (ISP) Collection

Research Question: What are the major socio-demographic risk factors influencing the rate of preterm birth in Valparaiso, Chile? Objectives: The objective of this study is to identify risk factors that influence the rate of preterm birth in an urban population of women living in Valparaiso, Chile. This study aims to understand whether a relationship exists between socio-demographic characteristics, such as economic level, education, lifestyle, access to medical attention and resources and the risk of prematurity. The outcomes of this study seek to determine the major biological, cultural, and social relationships and identify at-risk social groups. Additionally, this study considers the …

The Children Of Lehi And The Jews Of Sepharad, Shon D. Hopkins, D. Chad Richardson

BYU Studies

The Book of Mormon strongly asserts a gathering, not only of Lehi's scattered seed but also of the "Jews." Both Lehi (quoting Joseph of Egypt) and the Old Testament prophet Ezekiel prophesied of a running together of the children of Joseph and the children of Judah. This paper proposes one way in which this prophesied unification of Joseph and Judah into "one nation" may have been in part fulfilled, namely in a joining of the Jews of Sepharad (Sephardic Jews) with the children of Lehi. This occurred when the Sephardic Jews (coming primarily from Spain and Portugal) intermarried with the …

Mitt, Greg Whiteley, Hunter Phillips

BYU Studies

Independent of political ideology, the 2012 election signified the apex of the "Mormon Moment," a period during which The Church of Jesus Christ of Latter-day Saints occupied a greater space in the public consciousness than perhaps ever before. This moment was defined largely by Republican candidate Mitt Romney, arguably the most wellknown Mormon to those outside the Church. His ascendance to the presidential nomination was a historic moment for the Church and its members, for whom national relevance represents a major shift in their self-awareness. Despite his own ubiquity during the election cycle, Romney remains an enigma to the average …

The Mormons: An Illustrated History Of The Church Of Jesus Christ Of Latter-Day Saints, Roy A. Prete, Herman Du Toit

BYU Studies

Many predicted that the printed book would be doomed by developments in digital media. Far from it. This sumptuously illustrated "coffee table" hardcover publication by Merrell, an independent British publisher, testifies to the value of the printed book. The materiality of the medium emphasizes the synthesis of the complex visual and textual content of this publication--stressing the fact that this is a book and not a digital file after all. Stephen Hales Creative Inc., a design company in Provo, Utah, was responsible for the appealing visual design and layout of the book. The hard cover and dust jacket are both …

Full Issue, Byu Studies

BYU Studies

No abstract provided.

Analyzing Shakespeare’S Plays In A Network Perspective, Vikas Thotakuri

Student Work

Networks are popular models for representing interactions between entities in systems, such as in sociology, bioinformatics, and epidemiology. The entities in the networks are represented as vertices and their pair-wise interactions are represented as edges [1]. Many network metrics such as degree centrality (number of connections of an entity) and betweenness centrality (number of shortest paths passing through the entity) have been developed to rank the entities according to their importance [7] [10].Social networks are generally modeled on only one type of relation. Groups are open-ended, which means the number of participants and the time frame are not finite. Time …

The Eastern Echo, December 1, 2014, Eastern Michigan University

EMU Student Newspaper: The Normal News & The Eastern Echo

No abstract provided.

Virginia Accomplishments Since The 2008 Climate Action Plan Release, Center For Coastal Resources Management, Virginia Institute Of Marine Science, Governor's Climate Change And Resiliency Update Commission

2014, Adaptive Planning for Flooding and Coastal Change in Virginia: Next Steps for the Commonwealth

No abstract provided.

December 2014 Commencement Program, Bowling Green State University

Commencement Programs

No abstract provided.

Sexual Violence And Sub-Saharan Migrants In Morocco: A Community-Based Participatory Assessment Using Respondent Driven Sampling, Ines Keygnaert, Abdessamad Dialmy, Altay Manço, Jeroen Keygnaert, Nicole Vettenburg, Kristien Roelens, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Background: The European Union contracted Morocco to regulate migration from so-called “transit migrants” from Morocco to Europe via the European Neighbourhood Policy. Yet, international organisations signal that human, asylum and refugee rights are not upheld in Morocco and that many sub-Saharan migrants suffer from ill-health and violence. Hence, our study aimed at 1) investigating the nature of violence that sub-Saharan migrants experience around and in Morocco, 2) assessing which determinants they perceive as decisive and 3) formulating prevention recommendations.

Methods: Applying Community-Based Participatory Research, we trained twelve sub-Saharan migrants as Community Researchers to conduct in-depth interviews with peers, using Respondent …

Experimental Validation Of A New Distributed Cooperative Control Algorithm For Multi-Agent Systems With Switching Communication Topologies And Time-Delays, Junzhen Shao

Doctoral Dissertations and Master's Theses

In this thesis, we present practical experimental results to demonstrate a control law for consensus of multiagent systems with switching topologies and time delays. The nonlinear control law utilizes discontinuous cooperative control gains and uses contraction mapping to achieve consensus of multiagent systems. The testing platform we used consists of a number of mobile robots and software simulations both in Matlab and Microsoft Studio C++. We present the effectiveness of the control law design by Aria mobile robots with applications in distributed cooperative formation control. Computer simulations and hardware experiments presented include point consensus control and formation control, both with …

Human Behavior During Spaceflight: Evidence From An Analog Environment, Kenny Mikael Arnaldi

Doctoral Dissertations and Master's Theses

Spaceflight offers a multitude of stressors to humans living and working in space, originating from the external space environment and the life-support system. Future space participants may be ordinary people with different medical and psychosocial backgrounds who may not receive the intense spaceflight preparation of astronauts. Consequently, during a mission, a space participant’s mood and behavior could differ from a trained astronaut. This study was an exploratory research project that used an artificial habitat to replicate an orbital environment and the activities performed by humans in space. The study evaluated whether the type of environment affects mood and temperament. Two …

Multi-­‐Method Assessment Of Isil, Michael Nagata, Ali Abbas, Scott Atran, Bill Braniff, Andrew Bringuel, Muayyad Al-Chalabi, Sarah Canna, Jocelyne Cesari, Jacquelynn Chinn, Jon Cole, Steven Corman, Jonathon Cosgrove, Allison Astorino-Courtois, John Crowe, Richard Davis, Natalie Flora, James Giordano, Craig Giorgis, Mackenzie Harms, Benjamin Jensen, Richard John, Randy Kluver, Larry Kuznar, Gina Ligon, Leif Lundmark, Clark Mccauley, William H. Moon, Sophia Moskalenko, Dan Myers, Ryan Pereira, Stacy Pollard, Philip Potter, Hammad Sheikh, Johannes Siebert, Peter Simi, Lee Slusher, Anne Speckhard, Jason Spitaletta, Laura Steckman, Shalini Venturelli, Jeff Weyers, Lydia Wilson, Detlof Von Winterfeldt

Sociology Faculty Articles and Research

"The contents of this paper reflect some of the work that Dr. Cabayan and his colleagues are doing to help us understand and comprehend this “intangible power” across a unique enterprise of academicians, scientists, policy intellectuals, current and former Foreign Service, military, and intelligence professionals. Most importantly, their efforts to improve our comprehension will enable us to adjust our efforts, our operations, our investments, and our risk-­‐calculations to more effectively contest it and the organization that wields it. I am grateful for their tireless work in this regard, and I commend it to the reader."

Cloning And Expression Of A Tobacco Stearoyl-Acp Desaturase Gene Sbip24 And Its Interaction With Sabp2 In Sa Pathway, Amin J. Ferdous

Electronic Theses and Dissertations

Salicylic acid binding protein 2 (SABP2) that converts methyl salicylate to salicylic acid (SA) plays an obligatory role in the SA-mediated disease resistance pathway in plants. SABP2 interacts with SBIP24 in a yeast two-hybrid screening. SBIP24 belongs to the stearoyl-acyl carrier protein-desaturase protein family. To biochemically characterize the SBIP24, it was cloned from tobacco leaves using RT-PCR and expressed in E. coli. Recombinant SBIP24 was affinity purified using Ni-NTA chromatography. RT-PCR was performed to determine the role of SABP2 in modulating the expression SBIP24. TMV infected transgenic C3 (control tobacco plant containing empty silencing vector) and 1-2 (SABP2-silenced) …

Impulsivity, Venturesomeness, And Pride: Potential Moderators Of The Relationship Between Childhood Trauma, Substance Use, And Physical Aggression, Joshua P. Hatfield

Electronic Theses and Dissertations

Impulsivity, venturesomeness, and pride variables were examined as potential moderators of the associations between childhood trauma and physical aggression, alcohol use and physical aggression, and drug use and physical aggression. Participants (n = 457) were college students recruited from a university in the Southeast. It was hypothesized that childhood trauma, alcohol use, and drug use would be associated with increased scores of physical aggression. In addition, it was hypothesized that impulsivity, venturesomeness, authentic pride, and hubristic pride would moderate these relationships. Linear, multivariate hierarchical regression analyses were used to examine these variables as potential moderators. Hypotheses concerning hubristic pride as …

Gender Similarities And Differences In Experiences Of Public School Administrators, Marcia D. Fawver

Electronic Theses and Dissertations

The purpose of study was to examine similarities and differences in experiences between male and female high school principals and district administrators in addition to similarities and differences in leadership style and skills. This was an in-depth study with participants working in the same district and matched with descriptors such as age, similar position, and time served. Therefore the statement of the problem for the present study is what similarities and differences in experiences exist between male and female high school principals and district administrators in addition to similarities and differences in leadership style and skills.

Two male high school …

A Comprehensive Study Of The Effects Of Neurotoxins On Noradrenergic Phenotypes, Neuronal Responses And Potential Intervention By Antidepressants In Noradrenergic Cells, Yan Wang

Electronic Theses and Dissertations

It has been reported that locus coeruleus (LC) degeneration precedes the degeneration of other neurons in the brain in some neurodegenerative diseases like Alzheimer’s disease (AD) and Parkinson’s disease (PD). However, the precise mechanisms of neurodegeneration remain to be elucidated. N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP4) has been widely used as a noradrenergic neurotoxin in the development of AD and PD animal models for specific LC degeneration. However, the precise mechanism of action of DSP4 remains unclear. An increased systemic DNA damage caused by neurotoxin or oxidative stress has been found to be related to the pathogenic development of neurodegeneration. The process of neurodegeneration …

Identification, Cloning, And Expression Of Tobacco Responsive To Dehydration Like Protein (Rd22), Sbip-355 And Its Role In Sabp2 Mediated Sa Pathway In Plant Defense, Hanadi Abdulaali Almazroue

Electronic Theses and Dissertations

Abscisic acid (ABA) induces RD22, responsive to dehydration stress gene. Salicylic acid (SA) has been the focus of research due to its role against pathogens and abiotic stress. Interaction between ABA and SA signaling pathways is still poorly understood. SA-Binding Protein 2 (SABP2) converts methyl salicylate to SA. An attempt was made to identify proteins that interact with SABP2 using a yeast 2-hybrid screening. Several interactors were identified. One of them, SA-Binding Protein 2 Interacting Protein-355 (SBIP-355), showed high homology to RD22. Bioinformatic approaches showed that SBIP-355 contains a BURP domain. Phylogenetic analysis reveals that SBIP-355 clustered into the …

The Wolf Attacks: A History Of The Russo-Chechen Conflict, Christina E. Baxter

Electronic Theses and Dissertations

In the 1990s and early 2000s, the Chechens fought against the Russians for independence. The focus in the literature available has been on the wars and the atrocities caused by the wars. The literature then hypothesizes that the insurgency of today is just a continuation of the past. They do not focus on a major event in Chechen history: the Soviet liquidation of the Chechen-Ingush Autonomous Soviet Socialist Republic in 1944. It is this author’s assertion that the liquidation of the Chechen-Ingush ASSR forever changed the mindset of the people because it fractured a society that was once unified. This …

Winter 2014

Common Knowledge (2013-2019)

Notes from the dean; SNL opens door to the Illinois Supreme Court for one alumna; SNL helps alumnus land his dream career; Alumnus explores practical applications of the internet of things; SNL fosters lifelong curiousity--and an interest in post-impressionist art--in one alumnus; Alumna uses theatre to garner awareness about mental health issues; SNL's creative problem-solving methods help one alumnus craft his business solutions; SNL inspires lifelong career of social activism; Alumna looks to expand Chicago's tourism market; In memoriam Kumiko "Kumi" Watanuki EdD

Solar Brine Concentrator, Aric Gregory Fisher

Chemical Engineering Undergraduate Honors Theses

In arid regions of the United States potable water is a valuable resource and is sometimes produced using energy intensive processes by removing salts from brackish water. Task 4 provides a solar option for producing potable water from brackish water; in competing in Task 4, H2OGS has developed a simple, cost effective solar desalination process to provide these regions with necessary, potable water. H2OGS’ design takes into account WERC requirements, including cost, energy usage, worker safety, and easily obtained materials. U.S. government regulatory requirements are also taken into account as the proposed location for this process is Alamogordo, New Mexico. …

Werc: Solar Brine Concentrator, Sarah K. Haley

Chemical Engineering Undergraduate Honors Theses

In arid regions of the United States potable water is a valuable resource and is sometimes produced using energy intensive processes by removing salts from brackish water. Task 4 provides a solar option for producing potable water from brackish water; in competing in Task 4, H2OGS has developed a simple, cost effective solar desalination process to provide these regions with necessary, potable water. H2OGS’ design takes into account WERC requirements, including cost, energy usage, worker safety, and easily obtained materials. U.S. government regulatory requirements are also taken into account as the proposed location for this process is Alamogordo, New Mexico. …

Effect Of Nedd4 Haploinsufficiency On Insulin Sensitivity, Adiposity And Neuronal Behaviors, Jingjing Li

Theses and Dissertations (ETD)

The neural precursor cell expressed developmentally down-regulated gene 4 (NEDD4) is a HECT-type E3 ubiquitin ligase that has received broad attention in recent years. Many of its reported substrates are active players in metabolism, implying a potential role of NEDD4 itself in metabolic regulation. Since homozygous Nedd4 deletion leads to embryonic or perinatal lethality, we investigated the function of NEDD4 in metabolic regulation in vivo, using Nedd4- haploinsufficient mice in a high fat diet-induced obesity (HFDIO) model.

Our studies show that Nedd4-haploinsufficient mice fed a normal diet (ND) exhibited decreased body weight in both genders and proportionally reduced tissue mass …

Black Reflections: One Girl’S Exploration Of African-American Culture, Zoë Johnson

Senior Honors Theses

No abstract provided.