Digital Commons Network^™

Transient Elastography In Hepatitis B Virus Infection. Liver Stiffness Discrepancy Due To Sampling Location, Ting Wu, Lan Li, Hongwu Wang, Xiaoping Luo, Qin Ning

Saudi Medical Journal

OBJECTIVE: To investigate the variability in liver stiffness (LS), measured by transient elastography, and determine the possible influencing factors in hepatitis B virus infection. METHODS: This cross-sectional study was conducted at the Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China from March to June 2010. Three successful measurements at different sites in 123 patients were obtained, and the LS discrepancy was calculated. The influence of clinical data on the discrepancy was also assessed. RESULTS: The LS discrepancy was 1.3 (0.2-16.5) kPa and independently increased with a fibrosis stage: 0.9 …

Early Prevention Of Childhood Caries With Maternal Xylitol Consumption, Najlaa M. Alamoudi, Azza G. Hanno, Abdullah S. Almushayt, Mohammad I. Masoud

Saudi Medical Journal

OBJECTIVE: To evaluate the effect of maternal xylitol consumption on children9s salivary mutans streptococci (MS) level, caries activity, and plaque accumulation in contrast with maternal fluoride varnish in a group of mother-child pairs. METHODS: In this randomized controlled trial, the study subjects were 60 mother-child pairs recruited from the pediatric dentistry clinic and the hospital well baby clinic at King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia. The sample was recruited on the basis of maternal high salivary MS levels, and a child aged 10-36 months. The subjects were randomly assigned to experimental and control groups. Mothers in the experimental …

Paleoparasitological Studies On Mummies Of The Joseon Dynasty, Korea, Min Seo, Adauto Araújo, Karl J. Reinhard, Jong Yil Chai, Dong Hoon Shin

Karl Reinhard Publications

Paleoparasitology is the application of conventional or molecular investigative techniques to archeological samples in order to reveal parasitic infection patterns among past populations. Although pioneering studies already have reported key paleoparasitological findings around the world, the same sorts of studies had not, until very recently, been conducted in sufficient numbers in Korea. Mummified remains of individuals dating to the Korean Joseon Dynasty actually have proved very meaningful to concerned researchers, owing particularly to their superb preservation status, which makes them ideal subjects for paleoparasitological studies. Over the past several years, our study series on Korean mummies has yielded very pertinent …

Nutrition Transition In California: Examination Of The Nutrition Profile, Desiree Rodriguez

Social Sciences

No abstract provided.

Chlorovirus Skp1 And Core Ankyrin-Repeat Protein Interplay And Mimicry Of Cellular Ubiquitin Ligase Machinery, Eric Andrew Noel

School of Biological Sciences: Dissertations, Theses, and Student Research

The ubiquitin-proteasome system is a common target of several unrelated viruses that have evolved convergent strategies to redirect host ubiquitin machinery to serve their own needs. Members of the genus Chlorovirus, a group of large dsDNA viruses that infect certain freshwater chlorella-like green algae, encode a conserved Skp1 homolog and ankyrin-repeat (ANK) proteins, some of which contain C-terminal domains characteristic of cellular F-boxes or related viral PRANC domains. These observations suggested that this unique combination of chlorovirus proteins either interact with or imitate the key components of the SCF (Skp1-Cul1-F-box) ubiquitin ligases. Using mass spectrometry, we identified two functional …

Limiting What We Can Eat: A Bridge Too Far?, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

Innovative mayors across America are seeking to shape personal decisions about diet and physical activity, taking a page from tobacco control. But attempts to limit personal choices of what to eat have drawn the ire of vocal critics and sometimes the rebuke of judges, with former New York City mayor Michael Bloomberg’s limit on soda portions becoming a key flash point. The public broadly accepts state power to control infectious diseases, but often draws a line at limiting dietary choices. The author wants to dispel some of the well-worn arguments in the obesity wars.

Prevalence, Determinants, And Management Of Chronic Kidney Disease In Karachi, Pakistan - A Community Based Cross-Sectional Study., Saleem Jessani, Rasool Bux, Tazeen Jafar

Community Health Sciences

BACKGROUND:

Chronic kidney disease (CKD) is increasing being recognized as a global public health problem. However, there is dearth of information on the prevalence, determinants, and management of CKD from low- and middle-income countries. The objectives of the study were to determine the 1) prevalence of CKD; 2) socio-demographic and clinical factors associated with CKD; and 3) the existing management of these patients with regards to blood pressure control, and use of antihypertensive medications.

METHODS:

We conducted a cross-sectional study on 2873 participants aged ≥ 40 years in 12 representative communities in Karachi, Pakistan. The primary outcome was clinically significant …

What Clinical Approaches Have Service Providers Observed To Be Most Effective When Treating Young Survivors Of Human Sex Trafficking?, Elisa Lopez

Electronic Theses, Projects, and Dissertations

Human sex trafficking of minors is generally thought of as a problem that occurs in third world countries; however recent incidents have begun to shine a light on domestic sex trafficking happening in the United States. Qualitative interviews were conducted with seven participants who work with this population and explored treatment approaches they have observed to be effective when treating victims. The common theme was the use of Trauma Focused-Cognitive Behavioral Therapy (TF-CBT), especially when gathering information surrounding the trauma. It is important to note that although TF-CBT has been observed to be effective it does not meet all of …

Oceano Community Health Plan, Eugene Phillip Brennan

Master's Theses

ABSTRACT

Oceano Community Health Plan

Phillip Brennan

Recent, mounting research shows that chronic disease, the leading causes of death and primary driver of health care costs, cannot be effectively addressed through education or preventative health alone. A physical environment that promotes health—through access to healthy food, opportunities for physical activity, quality housing, transportation options, and safe schools—is an integral part of making our communities healthier. This research and accompanying Healthy Community Plans will serve as a way for the County to begin looking in-depth at the ways the built environment (our streets, parks, and neighborhoods) contribute or detract from the …

Commencement, Philadelphia (2014), Philadelphia College Of Osteopathic Medicine

Commencements

No abstract provided.

The Common Bacterial Pathogenes Isolated From Blood Culture In Paediatric Patients, Khalidah K. Abbas, Wifaq . M. Ali Al-Wattar, Atika A. Jasim

Baghdad Science Journal

Fever is a common illness in the pediatric age group ,the causes could be viral ,bacterial and fungal , this study was focused on bacterial pathogens as gram positive like Staphylococci, coagulase positive or negative ,Streptococci and gram negative like E-coli , Klebsialla ,Proteus, Pseudomonas, Burkhoderia , Acinetobacter and others like Pusturella ,E-alkalescendiaper, Haemophillus influenza and yeast like candida . Four thousand and seventy eight blood samples (4078)were collected in a period between January 2011 and the end of May 2012 at the child welfare hospital ,all the samples were cultured on suitable culture media and then biochemical tests were …

Determination Of Total Phenol, Antioxidant And Antimicrobial Activities Of Avena Sativa And Ocimum Basilicum, Farah D. Salim, Sundus H. Ahmed, Anaam M. Abd, Shatha Z. Skben, Nuha Az. Ramadhan

Baghdad Science Journal

The present study investigated the total content of phenolic compounds, antioxidant and antimicrobial activities of water extracts oat (Avena sativa) and basil (Ocimum basilicum), medicinal plants. The Folin-ciocalteu reagent assay was used to estimate the total phenolic content of plants extract. The antioxidant capacity of the plants extract was tested by ferric reducing/antioxidant power Assay (FRAP) and ferric reducing scavenging activity using DPPH method, and the antimicrobial activity was measured against [Staphylococcus epidermidis; Staphylococcus aureus; Proteus spp.; Klebsiella spp.; Escherichia coli; Candida albicans] as tester strains. The total phenolic content of Avena sativa and Ocimum basilicum extracts revealed that the …

Effect Study The Of Acute Toxoplasmosis On Some Blood And Serum Parameters In Pregnant Women In Baghdad City, Hanaa K. Hamad

Baghdad Science Journal

In this study therate of infection in acute and chronic Toxoplasma gondiiparasite that causes toxoplasmosiswas determined. This studywasIncluded 120 blood samplesthat collectedfrom pregnant women revisions to some clinics and laboratories in Baghdad civilas well as 10 blood samples fromnon-infected women as a control group.All bloodsamples were collectedin the first three months ofthepregnancyperiodfor detection toxoplasmosisbyusing serological tests of testkit(Toxo,IgG.,Toxo,IgM).To detect antibodies specialized type of IgG &IgM in acute and the chronicinfectionby Electro Clia manner usinga Roche Cobas e411. The results showed that the total infection rate was (55.83)%, therate ofinfection in acute (17.5)% While the rate of chronic infection was (38.33)%. …

Biological Activity And Protease Inhibitor From Watery Extract Of Lentil (Lens Culinaris) Against Some Bacterial Species, Khulood A Al-Khafaji, Salman A. Hammood, Sahar G Omran, Manal A Hassan, Husham J Yaseen, Abood H, Suhaila G. Ali

Baghdad Science Journal

Biological activity substances was investigated in watery extract of lentil which found to contain phenols, tannin, saponins and resins while, flavons, terpens and steroids were not exist in the extract details explained that 5%, 10% of lentil extract largly inhibited the growth of Psedumonas aeruginosa then Escherichia coli and Bacillus subtilis. The growth of both Staphylococcus aureus and Salmonella typhimurium were slightly affected by all extract concentration. Extracellular protease were screened in all bacterial species under study. Complete inhibition was achieved for extracellular protease while different percentage of protease inhibition were seen for intracellular proteases.

Drug Resistant Tuberculosis: Challenges Of Urbanization, Rumina Hasan

Department of Pathology and Laboratory Medicine

No abstract provided.

Household Malaria Knowledge And Its Association With Bednet Ownership In Settings Without Large–Scale Distribution Programs: Evidence From Rural Madagascar, Paul J. Krezanoski, Alexander C. Tsai, Davidson H. Hamer, Alison B. Comfort, David Bangsberg

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background Insecticide–treated bednets are effective at preventing malaria. This study focuses on household–level factors that are associated with bednet ownership in a rural area of Madagascar which had not been a recipient of large–scale ITN distribution.

Methods Data were gathered on individual and household characteristics, malaria knowledge, household assets and bednet ownership. Principal components analysis was used to construct both a wealth index based on household assets and a malaria knowledge index based on responses to questions about malaria. Bivariate and multivariate regressions were used to determine predictors of household bednet ownership and malaria knowledge.

Results Forty–seven of 560 households …

Stc.Unm: The Impact Of Start-Up Companies On The New Mexico Economy, Bureau Of Business And Economic Research

BBER Publications

STC.UNM (STC) is the technology transfer and economic development organization of the University of New Mexico. STC, a nonprofit corporation formed to protect and commercialize faculty inventions, asked the Bureau of Business and Economic Research (BBER) to conduct a study of the economic impact on New Mexico of start-up companies using STC technologies. BBER conducted similar analyses in 2011 and 2004. BBER found that in 2013, these start-up companies attracted $17.5 million in venture capital money to the state; had sales of $3.6 million; paid over $5.9 million in salary and benefits to 83 employees, with an average compensation of …

Individual, Disease, And Work-Related Factors Associated With Work Patterns, Presenteeism And Sick Pay Policy Of The Colorectal Cancer Survivor After Treatment, Kristin A. Roper

Graduate Doctoral Dissertations

Participation of colorectal cancer survivors (CRC) in the workforce has been described by clinicians, survivors, and researchers as a way to improve mood, quality of life (QOL), and survival. Maintaining self-esteem and financial independence have also been attributed to continued employment of the CRC survivor. The purpose of this cross-sectional survey was to describe patterns of employment of the CRC survivor and to examine the individual, disease, and work-related factors that influence presenteeism and perceived adequacy of sick pay (ASP) policy. The Conceptual Model of Nursing and Health Policy and the Pathways to Work Life Recovery guided the design, selection …

Identification Of Genes Required For Soil Survival In Burkholderia Thailandensis By Transposon-Directed Insertion Site Sequencing, Ah Bishop, Pa Rachwal

School of Biological and Marine Sciences

Transposon-directed insertion site sequencing was used to identify genes required by Burkholderia thailandensis to survive in plant/soil microcosms. A total of 1,153 genetic loci fulfilled the criteria as being likely to encode survival characteristics. Of these, 203 (17.6 %) were associated with uptake and transport systems; 463 loci (40.1 %) coded for enzymatic properties, 99 of these (21.4 %) had reduction/oxidation functions; 117 (10.1 %) were gene regulation or sensory loci; 61 (5.3 %) encoded structural proteins found in the cell envelope or with enzymatic activities related to it, distinct from these, 46 (4.0 %) were involved in chemotaxis and …

Partially-Latent Class Models (Plcm) For Case-Control Studies Of Childhood Pneumonia Etiology, Zhenke Wu, Maria Deloria-Knoll, Laura L. Hammitt, Scott L. Zeger

Johns Hopkins University, Dept. of Biostatistics Working Papers

In population studies on the etiology of disease, one goal is the estimation of the fraction of cases attributable to each of several causes. For example, pneumonia is a clinical diagnosis of lung infection that may be caused by viral, bacterial, fungal, or other pathogens. The study of pneumonia etiology is challenging because directly sampling from the lung to identify the etiologic pathogen is not standard clinical practice in most settings. Instead, measurements from multiple peripheral specimens are made. This paper considers the problem of estimating the population etiology distribution and the individual etiology probabilities. We formulate the scientific …

Pneumonia Pada Anak Balita Di Indonesia, Athena Anwar, Ika Dharmayanti

Kesmas

Pneumonia adalah penyakit infeksi yang merupakan penyebab utama kematian pada balita di dunia. Riset Kesehatan Dasar (Riskesdas) tahun 2007 melaporkan bahwa kematian balita di Indonesia mencapai 15,5%. Penelitian ini bertujuan untuk mengidentifikasi faktor determinan terjadinya pneumonia pada balita di Indonesia. Desain penelitian ini adalah potong lintang dengan menggunakan data Riskesdas 2013. Kriteria sampel adalah balita (0 – 59 bulan) yang menjadi responden Riskesdas 2013. Variabel dependen adalah kejadian pneumonia balita, sedangkan variabel independennya adalah karakteristik individu, lingkungan fisik rumah, perilaku penggunaan bahan bakar, dan kebiasaan merokok. Penetapan kejadian pneumonia berdasarkan hasil wawancara, dengan batasan operasional diagnosis pneumonia oleh tenaga kesehatan …

Investigating The Role Of Social Environmental Stress And Implicit Motives In Predicting Salivary Alpha-Amylase Reactivity To The Social Competence Interview, Jun A. He

Theses - ALL

Salivary alpha-amylase is emerging as a promising proxy for assessing sympathetic-adrenal-medullary (SAM) axis activity. However, it is not known whether a brief semi-structured behavioral assessment, such as the social competence interview (SCI), also elicits alpha-amylase changes. I hypothesized that (1) the SCI would elicit alpha amylase reactivity, (2) social environmental stress (i.e, high levels of exposure to violence during childhood and low perceived community social status) would predict the alpha-amylase response to the interview and (3) that agonistic striving would mediate the relationship between social environmental stress and amylase reactivity. The study sample was comprised of healthy young adults aged …

Electrochemical Control Of Bacterial Persister Cells, Tagbo Herman Roland Niepa

Dissertations - ALL

The emergence of antibiotic-resistant bacteria has presented an increasing challenge to infection control. Conventional methods of antibacterial treatment involving high dose of antibiotics or surgical intervention have proven insufficient for eradicating persistent infections, such as those associated with medical implants. It is well recognized that bacterial populations commonly contain a small percentage of phenotypic variants, known as persister cells, which are metabolically inactive and extremely tolerant to antibiotics. When the antibiotic treatment is stopped, surviving persister cells can regenerate the bacterial population with a similar percentage of persister cells. Thus, persistence presents a great challenge to curing chronic infections.

In …

Hiv And Sti Risk For Young Blacks In High Prevalence Areas: Implications For Health Equity In Communities Hosting Historically Black Colleges And Universities (Hbcus), Tanya Telfair Leblanc, Madeline Y. Sutton, Peter Thomas, Wayne A. Duffus

Journal of Health Disparities Research and Practice

Background

Every year, thousands of young, black, high school graduates who are seeking higher education, attend one of the 105 historically black colleges and universities (HBCUs) located primarily in the south and east. The objective of the research was to examine the geographic proximity of HBCUs to areas of high HIV and STI disease burden among college age people to assess infectivity of potential sex partners in the areas surrounding HBCUs.

Methods

We examined the 14 states reporting the greatest HIV diagnoses burden among persons age 20-24 years old and STI burden among persons age 15 to 24 years old …

Editor's Notes, Melva V. Thompson-Robinson, Marya Shegog

Journal of Health Disparities Research and Practice

No abstract provided.

Practice-Based Learning: Opportunities And Implications For Stem Education, Glen P. Mays

Health Management and Policy Presentations

This presentation examines how practice-based research strategies have been used to produce new knowledge and stimulate learning about how to improve the organization, financing, and delivery of public health services. I consider how practice-based research strategies can be adapted to advance knowledge and practice related to science, technology, engineering and mathematics (STEM) education and application.

Enhancing Student Learning Outcomes Through Increased Predeparture Preparation For Study Abroad, Catherine J. Raleigh

Capstone Collection

Numerous studies have shown that each year, more students in the United States choose to study abroad. Some universities have even taken steps to make international study a requirement. Similar to the increased competitiveness for students to attend and thereafter, to stand out in college, making the most of one’s overseas experience, going to more exotic locations and delving deeper into the local culture, will follow in this pattern as a means to be more competitive upon graduation. Increased awareness of the needs of students studying abroad will need to be addressed and students across the spectrum of both mental …

Localization And Functional Analysis Of Dictyostelium Discoideum Gtpases, Rabs And Rab2, Katherine V. Maringer

Theses and Dissertations

Dictyostelium discoideum is a simple eukaryotic amoeba that has proven useful in studying various aspects of endosomal and lysosomal membrane trafficking, as well as development. The Rab family of small molecular weight GTPases has been implemented in several cellular processes to include various vesicle trafficking roles, cell-cell signaling, and development. This study focuses on the localization and function of two Dictyostelium GTPases, RabS, and Rab2 which we hypothesized to both localize to the Golgi, and the contractile vacuole system. Expression of GFP-tagged DdRab2, and DdRabS proteins revealed similar localization to ER-Golgi membranes as well as the contractile vacuole system. Microscopic …

A Global Compendium Of Human Dengue Virus Occurrence, Jane P. Messina, Oliver J Brady, David M. Pigott, John S. Brownstein, Anne Hoen, Simon Hay

Dartmouth Scholarship

A global geographic database of human dengue virus occurrence was produced to generate a global risk map and associated burden estimates1. Herein we present the database, which comprises occurrence data linked to point or polygon locations, derived from peer-reviewed literature and case reports as well as informal online sources. Entries date from 1960 to 2012. We describe all data collection processes in full, as well as geo-positioning, database management and quality-control procedures. This is the most comprehensive database of confirmed human dengue infection to-date, consisting of 8,309 geo-positioned occurrences in total.

Equine Arteritis Virus Does Not Induce Interferon Production In Equine Endothelial Cells: Identification Of Nonstructural Protein 1 As A Main Interferon Antagonist, Yun Young Go, Yanhua Li, Zhenhai Chen, Mingyuan Han, Dongwan Yoo, Ying Fang, Udeni B. R. Balasuriya

Veterinary Science Faculty Publications

The objective of this study was to investigate the effect of equine arteritis virus (EAV) on type I interferon (IFN) production. Equine endothelial cells (EECs) were infected with the virulent Bucyrus strain (VBS) of EAV and expression of IFN-β was measured at mRNA and protein levels by quantitative real-time RT-PCR and IFN bioassay using vesicular stomatitis virus expressing the green fluorescence protein (VSV-GFP), respectively. Quantitative RT-PCR results showed that IFN-β mRNA levels in EECs infected with EAV VBS were not increased compared to those in mock-infected cells. Consistent with quantitative RT-PCR, Sendai virus- (SeV-) induced type I IFN production was …